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1.
Rev. bras. med. esporte ; 27(3): 295-298, July-Sept. 2021. graf
Article in English | LILACS | ID: biblio-1288566

ABSTRACT

ABSTRACT Introduction Skeletal muscle injuries account for 10% to 50% of treadmill sports injuries. Insulin-like growth factor (IGF) is a family of polypeptides with both insulin-like anabolic and growth-promoting effects. Sports play a vital role in the recovery of skeletal muscle injuries. Objective The paper analyzes the ability of insulin-like growth factor 1 (IGF-1) to repair skeletal muscle injury caused by treadmill exercise. Method We injected drugs under the wound after exercise-induced injury in rats. The control group was injected with saline, and the experimental group was injected with an insulin-like growth factor. We conduct histological and electron microscopic structural analysis of rats, Results: After an injury, the experimental group formed a basal lamina protective film earlier than the control group, activated myoblasts, formed myofilaments, formed myotubes, and fused into muscle fibers earlier than the control group. The healing quality was also better. The experimental group was endogenous. The mRNA content of sex IGF-1 and IGF-2 both increased earlier than the control group. Conclusion Local injection of exogenous insulin-like growth factor-1 can stimulate the proliferation of myoblasts and accelerate the post-traumatic repair process of skeletal muscle caused by treadmill sports. Level of evidence II; Therapeutic studies - investigation of treatment results.


RESUMO Introdução As lesões do músculo esquelético representam de 10% a 50% das lesões em esteira esportiva. O fator de crescimento semelhante à insulina (IGF) é uma família de polipeptídeos com efeitos anabólicos e de promoção do crescimento semelhantes à insulina. Os esportes desempenham um papel vital na recuperação de lesões musculares esqueléticas. Objetivo o artigo analisa a capacidade do fator de crescimento semelhante à insulina 1 (IGF-1) em reparar lesões musculares esqueléticas causadas por exercícios em esteira. Método Injetamos drogas sob a ferida após lesão induzida por exercício em ratos. O grupo controle foi injetado com solução salina e o grupo experimental foi injetado com um fator de crescimento semelhante à insulina. Realizamos análises histológicas e microscópicas eletrônicas estruturais de ratos. Resultados Após a lesão, o grupo experimental formou um filme protetor da lâmina basal mais cedo do que o grupo controle, mioblastos ativados, miofilamentos formados, miotubos formados e fundidos em fibras musculares mais cedo do que o grupo controle. A qualidade da cura também foi melhor. O grupo experimental era endógeno. O conteúdo do sexo IGF-1 e IGF-2 mRNA aumentou mais cedo do que no grupo de controle. Conclusão A injeção local de fator de crescimento semelhante à insulina 1 exógeno pode estimular a proliferação de mioblastos e acelerar o processo de reparo muscular esquelético pós-traumático causado por esportes em esteira. Nível de evidência II; Estudos terapêuticos: investigação dos resultados do tratamento.


RESUMEN Introducción Las lesiones del músculo esquelético representan del 10% al 50% de las lesiones deportivas en cinta. El factor de crecimiento semejante a la insulina (IGF) es una familia de polipéptidos con efectos anabólicos y estimulantes del crecimiento semejantes a la insulina. Los deportes juegan un papel vital en la recuperación de las lesiones del músculo esquelético. Objetivo El artículo analiza la capacidad del factor de crecimiento semejante a la insulina 1 (IGF-1) para reparar la lesión del músculo esquelético causada por el ejercicio en cinta. Método inyectamos drogas debajo de la herida después de una lesión inducida por el ejercicio en ratas. Al grupo de control se le inyectó solución salina y al grupo experimental se le inyectó un factor de crecimiento semejante a la insulina. Realizamos análisis estructurales histológicos y microscópicos electrónicos de ratas, Resultados: Después de una lesión, el grupo experimental formó una película protectora de la lámina basal antes que el grupo de control, activó mioblastos, formó miofilamentos, formó miotubos y se fusionó en fibras musculares antes que el grupo de control. La calidad de curación también fue mejor. El grupo experimental fue endógeno. El contenido de ARNm de IGF-1 e IGF-2 de sexo aumentaron antes que en el grupo de control. Conclusión La inyección local de factor de crecimiento semejante a la insulina 1 exógeno puede estimular la proliferación de mioblastos y acelerar el proceso de reparación postraumático del músculo esquelético causado por los deportes en cinta. Nivel de evidencia II; Estudios terapéuticos: investigación de los resultados del tratamiento.


Subject(s)
Humans , Male , Rats , Wound Healing/drug effects , Insulin-Like Growth Factor I/administration & dosage , Muscle, Skeletal/injuries , Acute Disease , Muscle, Skeletal/drug effects , Muscle, Skeletal/ultrastructure , Disease Models, Animal
2.
Rev. bras. med. esporte ; 27(spe2): 54-57, Apr.-June 2021. graf
Article in English | LILACS | ID: biblio-1280093

ABSTRACT

ABSTRACT Soft tissue injury is the most common disease in orthopedics, and it is also the most easily neglected disease in sports. Without timely and effective treatment, it is easy to develop into malignant strain and seriously affect life and sports. In view of this, the aim of this study is to analyze the effect and mechanism of traditional Chinese medicine gel in treating such injuries in the light of the characteristics of sports-related soft tissue injury. The right gastrocnemius muscle injury was simulated in 36 adult male rats. Chinese medicine gel and tincture were used to treat it. The contents of interleukin, alanine aminotransferase, blood urea nitrogen and prostaglandin E2 in the blood of rats under different courses of treatment were analyzed to explore recovery in four rats. The results showed that the levels of interleukin and prostaglandin E2 in the blood of rats treated with drugs were significantly lower than those in the control group (p<0.05), indicating that both drugs have obvious therapeutic effects on soft tissue injury. The content of interleukin in the blood of the Chinese medicine gel group was slightly lower than that of the tincture group, indicating that the Chinese medicine gel could affect the recovery of soft tissue injury by affecting leukocyte interleukin. This result is helpful in the treatment of soft tissue injury in sports and to further improve the therapeutic effect of traditional Chinese medicine gel.


RESUMO A lesão dos tecidos moles é a doença mais comum na ortopedia, e é também a doença mais facilmente negligenciada nos esportes. Sem tratamento ágil e eficaz, facilmente evolui para luxações malignas, afetando seriamente a vida e a prática de esportes. Em vista disso, o objetivo deste estudo é analisar o efeito e o mecanismo do gel da medicina tradicional chinesa no tratamento de tais lesões, com base nas características da lesão dos tecidos moles relacionada à prática esportiva. Estimulou-se lesão do músculo gastrocnêmio direito em 36 ratos adultos. O gel e a tintura chinesa foram usados para o tratamento. Foram analisados os conteúdos de interleucina, alanina aminotransferase, ureia sanguínea azoto e prostaglandina E2 no sangue dos ratos sob diferentes tratamentos, de modo a explorar a recuperação de quatro ratos. Os resultados mostraram que os níveis de interleucina e prostaglandina E2 no sangue dos ratos tratados com medicamentos eram significativamente inferiores aos do grupo controle (p<0.05), indicando que ambos os fármacos têm efeitos terapêuticos óbvios sobre lesões dos tecidos moles. O teor de interleucina no sangue do grupo gel chinês medicinal mostrou-se ligeiramente inferior ao do grupo tintura, indicando que o gel medicinal chinês pode afetar a recuperação da lesão nos tecidos moles, afetando o leucócito interleucina. Este resultado é útil para o tratamento de lesões dos tecidos moles relacionadas à prática esportiva e para melhorar ainda mais o efeito terapêutico do gel da medicina chinesa tradicional.


RESUMEN La lesión de los tejidos blandos es la enfermedad más común en la ortopedia, y es también la enfermedad más fácilmente descuidada en los deportes. Sin tratamiento ágil y eficaz, fácilmente evolucionan a luxaciones malignas, afectando seriamente la vida y la práctica de deportes. En vista de eso, el objetivo de este estudio es analizar el efecto y el mecanismo del gel de la medicina tradicional china en el tratamiento de tales lesiones, con base en las características de la lesión de los tejidos blandos relacionada a la práctica deportiva. Se estimuló lesión del músculo gastrocnemio derecho en 36 ratones adultos. El gel y la tintura china fueron usados para el tratamiento. Fueron analizados los contenidos de interleucina, alanina aminotransferasa, urea sanguínea, nitrógeno y prostaglandina E2 en la sangre de los ratones bajo diferentes tratamientos, de modo de explorar la recuperación de cuatro ratones. Los resultados mostraron que los niveles de interleucina y prostaglandina E2 en la sangre de los ratones tratados con medicamentos eran significativamente inferiores a los del grupo control (p<0.05), indicando que ambos fármacos tienen efectos terapéuticos obvios sobre lesiones de los tejidos blandos. El tenor de interleucina en la sangre del grupo gel chino medicinal se mostró ligeramente inferior al del grupo tintura, indicando que el gel medicinal chino puede afectar la recuperación de la lesión en los tejidos blandos, afectando el leucocito interleucina. Este resultado es útil para el tratamiento de lesiones de los tejidos blandos relacionadas a la práctica deportiva y para mejorar aún más el efecto terapéutico del gel de la medicina china tradicional.


Subject(s)
Animals , Rats , Ointments/therapeutic use , Muscle, Skeletal/injuries , Medicine, Chinese Traditional , Athletic Injuries/drug therapy , Blood Urea Nitrogen , Dinoprostone/blood , Interleukins/blood , Treatment Outcome , Alanine Transaminase/blood , Disease Models, Animal
3.
Int. j. morphol ; 38(5): 1288-1295, oct. 2020. tab, graf
Article in English | LILACS | ID: biblio-1134438

ABSTRACT

SUMMARY: The aim of this study was to evaluate the effects of stretching and therapeutic ultrasound (TUS) on desmin and laminin contents of rat muscle after contusion. Male Wistar rats (n = 35, 8-9 weeks of age, 271 ± 14g body weight) were divided into five groups: Control group (CG) (n= 03); Injured group (IG) (n= 8); Injured + ultrasound group (IUSG) (n= 8); Injured+stretching group (ISG) (n= 8); Injured +ultrasound + stretching group (IUSSG) (n= 8). The application of ultrasound started 72 hours after the contusion, using the 50 % pulsed mode, 0.5 W/cm2, 5 min, once a day, for five consecutive days. Passive manual stretching was started on the tenth day after injury, with four repetitions of 30 s each and 30 s rest between repetitions, once a day, five times per week, for a total of ten applications. After 22 days, the rats were euthanazied and the gastrocnemius of both limbs removed for desmin and laminin immunohistochemistry morphometric measurement. Analysis was conducted using ANOVA one way post-hoc Tukey to parametric data and Kruskall-Wallis for non-parametric data. The IUSSG animals showed a larger area of desmin than ISG (p<0.05). It was found a decrease in laminin comparing IUSG to IG. However, laminin area was higher in ISG than all groups (p<0.05). UST isolated or in combination with stretching influenced gastrocnemius regeneration in different manners. While stretching applied isolated enhanced gastrocnemius regeneration noticed by the increase in laminin area, in combination with TUS strengthened the muscle healing rising desmin area.


RESUMEN: El objetivo de este estudio fue evaluar los efectos del estiramiento y la ecografía en los contenidos de desmina y laminina del músculo de rata después de la lesión. Ratas Wistar macho (n = 35, 8-9 semanas de edad, 271 ± 14 g de peso corporal) se dividieron en cinco grupos: grupo de control (CG) (n = 03); Grupo lesionado (GL) (n = 8); Lesionado + grupo de ultrasonido (LGU) (n= 8); Lesionado + grupo de estiramiento (LGE) (n = 8); Lesionado + ultrasonido + grupo de estiramiento (LUGE) (n = 8). La aplicación de ultrasonido comenzó 72 horas después de la lesión, usando el modo pulsado al 50 %, 0,5W / cm2, 5 min, una vez al día, durante cinco días consecutivos. El estiramiento manual pasivo se inició el décimo día después de la lesión, con cuatro repeticiones de 30 seg cada una y 30 seg de descanso entre repeticiones, una vez al día, cinco veces por semana, para un total de diez aplicaciones. Las ratas fueron sacrificadas después de 22 días, y se extrajo el músculo gastrocnemio de ambos miembros para la medición morfométrica de desmina y laminina a través de inmunohistoquímica. El análisis se realizó utilizando ANOVA unidireccional Tukey post-hoc para datos paramétricos y Kruskall-Wallis para datos no paramétricos. Los animales LUGE mostraron un área mayor de desmina que LGE (p <0,05). Se encontró una disminución en la laminina comparando LGU con GL. Sin embargo, el área de laminina fue mayor en LGE que en todos los grupos (p <0,05). El tratamiento con ultrasonido aislado o en combinación con estiramiento influyó en la regeneración del músculo gastrocnemio de diferentes maneras. Si bien el estiramiento aplicado, en combinación con tratamiento de ultrasonido, fortaleció el área de desmina, la regeneración del músculo gastrocnemio mejoró por el aumento en el área de laminina aumentando la curación muscular.


Subject(s)
Animals , Male , Rats , Ultrasonic Therapy/methods , Muscle, Skeletal/pathology , Contusions/therapy , Muscle Stretching Exercises/methods , Immunohistochemistry , Analysis of Variance , Laminin/analysis , Rats, Wistar , Muscle, Skeletal/injuries , Desmin/analysis
4.
Int. j. morphol ; 38(5): 1392-1397, oct. 2020. graf
Article in English | LILACS | ID: biblio-1134454

ABSTRACT

SUMMARY: Severe muscle injuries are common in accidents and have a delayed recovery of muscle integrity. In these cases, muscle suture surgery is the standard treatment. However, Platelet Rich Plasma (PRP), has been widely used in orthopedic injuries due to its growth factors. Thus, the objective of the study will be to analyze the association of suture and PRP techniques in the collagen and tenacity of the injured muscle. Were used seventy rats, divided into five groups: control (C), injury control (CI), injury and suture (IS), injury and PRP (IP), injury, suture, and PRP (ISP). Were sectioned approximately 50 % of the width and 100 % of the thickness of the gastrocnemius muscle. The homologous PRP was applied 24h after the injury. On the 7th day after the injury, the animals were euthanized and their muscles subjected to mechanical testing to measure tenacity or collagen analysis to calculate the ratio between type I and III collagen. The results show a significant decrease (p <0.05) in the values of the relationship between collagens in all injured groups (CI, IS, IP, ISP) compared to group C. In injured groups, the tenacity was significantly (p <0.05) reduced compared to the control group, with no observed difference between treatments and injured groups. The amount of collagen in the injured area has increased, but it did not affect the tenacity of the muscles, which was reduced.


RESUMEN: Las lesiones musculares graves son comunes durante los accidentes y la integridad del músculo está sujeta a una larga recuperación. En esos casos la cirugía, para la sutura del músculo, es el tratamiento común, no obstante el plasma rico en plaquetas (PRP) ha sido utilizado recientemente en lesiones ortopédicas, debido a sus factores del crecimiento. El objetivo del estudio fue analizar la asociación de las técnicas de sutura y PRP en la histología y tenacidad de músculo lesionado. Fueron utilizadas 70 ratas distribuidas en cinco grupos: control (C), control lesión (CL), lesión y sutura (LS), lesión y PRP (LPRP), lesión, sutura y PRP (LSPRP). Aproximadamente en la lesión, el 50 % de la longitud y el 100 % del espesor del músculo gastrocnemio fueron seccionados. El PRP homólogo fue aplicado 24 horas después de la lesión. En el 7º día después de la lesión los animales fueron eutanasiados y las muestras fueran sometidas al ensayo mecánico para la medición de la tenacidad y análisis del colágeno, para realizar el cálculo de la relación entre los colágenos I y III. Los resultados demostraron una reducción significativa (p<0,05) en los valores de la relación entre los colágenos en todos los grupos lesionados en relación al grupo C. La tenacidad fue (p<0,05) reducida significativamente en los grupos lesionados en relación al grupo control, sin diferencia entre los tratados. En la lesión muscular hubo disminución de los valores de colágeno, aunque en los tratamientos se observó elevación de la cantidad de colágeno en la área lesionada, esta no tuvo efecto en la tenacidad de los músculos que fue disminuida en la lesión.


Subject(s)
Animals , Male , Rats , Collagen/analysis , Muscle, Skeletal/injuries , Platelet-Rich Plasma , Muscular Diseases/therapy , Sutures , Rats, Wistar , Soft Tissue Injuries/therapy , Collagen Type I/analysis , Collagen Type III/analysis
5.
Int. j. morphol ; 38(3): 804-810, June 2020. tab, graf
Article in English | LILACS | ID: biblio-1098323

ABSTRACT

Honey is a natural antioxidant that its protective effects have been proven against ischemia-reperfusion (IR) injury. The aim of this study was to evaluate the ameliorative effect of Persian Honey, Apis mellifera meda skorikov, on gastrocnemius muscle IR injury. Eighty adult male Sprague-Dawley rats weighing 250-300 g were used. They were divided into ten groups (N=8 per group). The ischemia was conducted with a silk suture 6-0 using the slipknot technique. All groups were rendered in ischemic for 3 h, and reperfused for various times of 3 days (3-day reperfusion), 7 days (7-day reperfusion), 14 days (14-day reperfusion), and 28 days (28-day reperfusion). Half of the groups had experimental honey (5 %) treatment immediately after ischemia. After reperfusion, the rats, based on the grouping, were killed with high doses of anesthetic, and the gastrocnemius muscles were removed and fixed. After the tissue processing, the evaluation of edema and mast cells infiltration was performed with hematoxylin-eosin and toluidine blue staining, respectively. TNF-α was detected with immunohistochemistry method. The amount of TNF-α as an index of acute inflammatory except the 3rd day significantly decreased on the other day of reperfusion (7th, 147th and 287th days). The mast cells infiltration was significantly decreased on 77th and 147th days. The tissue edema was decreased significantly in honey administrated group in the comparison with placebo groups. Honey administration can reduce damage caused by ischemia-reperfusion in the rat gastrocnemius muscle.


La miel es un antioxidante natural; sus efectos protectores han sido probados contra la lesión por isquemiareperfusión (IR). El objetivo de este estudio fue evaluar el efecto de mejora de la miel persa Apis mellifera meda skorikov, en la lesión por IR del músculo gastrocnemio. Se utilizaron 80 ratas Sprague-Dawley macho adultas con un peso entre 250 y 300 g divididas en diez grupos (N = 8 por grupo). La isquemia se realizó con una sutura de seda 6-0 utilizando la técnica slipknot permaneciendo isquémicos durante 3 h. La reperfusión se realizó durante varios tiempos de 3 días, 7 días (reperfusión de 7 días), 14 días (reperfusión de 14 días) y 28 días (28 días reperfusión). La mitad de los grupos recibió tratamiento experimental con miel (5 %) inmediatamente después de la isquemia. Después de la reperfusión, las ratas, fueron sacrificadas con altas dosis de anestésico, y los músculos gastrocnemios fueron removidos y fijados. Después de procesar el tejido, se realizó la evaluación del edema y la infiltración de mastocitos se realizó con tinción de hematoxilina-eosina y azul de toluidina, respectivamente. TNF-α se detectó con el método de inmunohistoquímica. La cantidad de TNF-α como índice de inflamación inflamatoria aguda, excepto en el tercer día, disminuyó significativamente al día siguiente de la reperfusión (7, 14 y 28 días). La infiltración de mastocitos disminuyó significativamente a los 7 y 14 días. El edema tisular disminuyó significativamente en el grupo administrado con miel en comparación con los grupos placebo. El tratamiento con miel puede reducir el daño causado por la isquemia-reperfusión en el músculo gastrocnemio de la rata.


Subject(s)
Animals , Male , Rats , Reperfusion Injury/complications , Apis mellifica/administration & dosage , Muscle, Skeletal/injuries , Honey , Immunohistochemistry , Reperfusion Injury/drug therapy , Apis mellifica/pharmacology , Rats, Sprague-Dawley , Muscle, Skeletal/drug effects , Protective Agents
6.
Salud trab. (Maracay) ; 28(1): 35-45, jun. 2020. tab
Article in Spanish | LILACS, LIVECS | ID: biblio-1104332

ABSTRACT

El presente artículo identificó la prevalencia de síntomas de trastornos músculo esquelético relacionados al trabajo en extremidades superiores y su relación con algunos factores de riesgo vinculados al desempeño de las tareas, factores psicosociales, sexo, edad y antigüedad laboral. Utilizando un diseño exploratorio, correlacional y una muestra por conveniencia de 45 trabajadores (hombres/mujeres). Se exploró la presencia de síntomas mediante el cuestionario nórdico estandarizado para población chilena; la repetitividad, postura forzada, fuerza y algunos factores ambientales mediante la norma técnica para identificación y evaluación de factores de riesgo de Trastornos Musculo esqueléticos relacionados con el trabajo del Ministerio de Salud chileno, los factores psicosociales mediante el cuestionario de SUSESO-ISTAS 21 versión breve, y la edad, sexo y antigüedad laboral mediante una ficha propuesta por los autores. Los resultados (año 2017) muestran que el 8 % de los trabajadores no manifestó síntomas en extremidad superior y espalda. Que 48.9% de trabajadores sintomáticos son hombres y menores de 45 años (55.6%) de antigüedad laboral inferior de 5 años (73.4%). No se observó diferencias estadísticas entre exigencia psicosocial y presencia de síntomas de Trastornos Musculo esqueléticos. No obstante el 51.6% de los trabajadores sintomáticos de Trastornos Musculo esqueléticos, tenía nivel alto de riesgo psicosocial para la dimensión doble presencia. Se concluye que para el control y la prevención Trastornos Musculo esqueléticos en el trabajo es imprescindible el conocimiento de la población laboral a proteger y adoptar un enfoque biopsicosocial amplio que genere información para actuar racionalmente y con expectativas de solución(AU)


This study measured the prevalence of musculoskeletal symptoms related to work using the upper extremities and their relationship to risk factors linked to task performance, psychosocial risk factors, sex, age and length of employment. The study design was exploratory and correlational, conducted in a convenience sample of 45 workers. The presence of symptoms was explored using the Nordic Musculoskeletal Questionnaire for a Chilean population, along with repetitiveness, forced posture, strength. Environmental factors were explored using the standard identification and evaluation of risk factors based on the Work-related Musculoskeletal Disorders inventory (TMERT in Spanish) of the Chilean Ministry of Health. Psychosocial factors were explored using the short version (21 items) of the Psychosocial Risk of the Workplace (SUSESOISTAS in Spanish) questionnaire, which explores age, sex and length of employment. Results in 2017 show that 8% of workers reported no symptoms in the upper extremity or back. In addition, 48.9% of symptomatic workers were men under 45 years of age (55.6%), with less than 5 years of employment (73.4%). No statistically significant differences were observed between psychosocial demands and presence of musculoskeletal symptoms. However, 51.6% of workers with musculoskeletal symptoms had high levels of psychosocial risk for the dual presence. We conclude that specific knowledge of the working population is essential in order to protect them and to control and prevent musculoskeletal disorders at work. In addition, a comprehensive biopsychosocial approach that generates information to act rationally and with expectations of finding solutions must be adopted(AU)


Subject(s)
Humans , Back , Occupational Risks , Risk Factors , Muscle, Skeletal/injuries , Upper Extremity , Task Performance and Analysis , Surveys and Questionnaires , Occupational Groups
7.
Rev. bras. ortop ; 54(1): 6-12, Jan.-Feb. 2019. tab, graf
Article in English | LILACS | ID: biblio-1003600

ABSTRACT

Abstract Objectives To correlate the mean time of return of athletes to sport after acute injury of the thigh muscle with hematoma that was punctured or not. Methods Study based on clinical intervention, controlled and non-randomized with 20 amateur and professional athletes, divided into moderate and total or subtotal thighs lesions, according with the Munich Consensus Statement. Nine athletes were included in the intervention group and 11 athletes in the control group. In the intervention group, the athletes were submitted to a puncture of the hematoma, associated to physical therapy; the control group did only physical therapy. The variable mean time of return to sport was analyzed using the Mann-Whitney test and a significance level of 5% (p < 0.05; 95% confidence interval [CI]) was established. Results The mean group was composed mostly of men, eight of them were amateur athletes. There were three women, two of whom were amateur athletes. The average age of participants was 34.70 ± 12.79 years. There were 13 patients with posterior thigh lesions, 5 with anterior lesions and two with adductor lesions. Considering all injuries, the mean time of return to sport was of 48.50 ± 27.50 days in the intervention group. In the control group, this period was of 102.09 ± 52.02 days, showing a statistically significant difference between them (p = 0.022). Conclusion In the present study, hematoma drainage in athletes with moderate and total or subtotal muscle injuries associated with hematomas decreased their return time to sport.


Resumo Objetivos Comparar o tempo médio de retorno dos atletas ao esporte após lesão muscular aguda da coxa com hematoma que foi ou não puncionado. Métodos Estudolongitudinal de intervenção clínica, controlado e não randomizado, com participação de 20 atletas amadores e profissionais com lesão muscular aguda do tipo parcial moderada ou (sub)total na região da coxa, segundo a classificação do Consenso de Munique. Nove atletas foram incluídos no grupo intervenção e 11 no grupo controle. Os atletas do grupo intervenção foramsubmetidos a punção do hematoma e fisioterapia e os do grupo controle, apenas a fisioterapia. A variável tempo de retorno ao esporte foi analisada como teste deMann-Whitney e o nível de significância usado foi 95% (p < 0,05). Resultados A população estudada foi composta principalmente por homens, dos quais oito eram praticantes de esportes no nível amador. Três mulheres, das quais duas eram amadoras, foram incluídas no estudo. A média de idade dos participantes foi de 34,70 ± 12,79 anos. Houve 13 indivíduos com lesões na região posterior da coxa, cinco comlesões na região anterior e dois com lesões na região adutora. Considerando todas as lesões, o tempo médio de retorno ao esporte foi de 48,50 ± 27,50 dias no grupo intervenção. Já no grupo controle, esse intervalo foi de 102,09 ± 52,02 dias (p = 0,022). Conclusão No presente estudo, a punção do hematoma muscular mostrou-se efetiva em abreviar o tempo de retorno ao esporte dos atletas com lesões musculares parciais moderadas e (sub)totais associadas a hematomas. Abstract Objectives To correlate the mean time of return of athletes to sport after acute injury of the thigh muscle with hematoma that was punctured or not.


Subject(s)
Humans , Male , Female , Thigh , Drainage , Muscle, Skeletal/injuries , Athletes , Hematoma
8.
Article in Spanish | LILACS, BINACIS | ID: biblio-1048313

ABSTRACT

Introducción: El Tennis Leg o pierna de tenista se llama a el desgarro de la unión miotendinosa distal del gemelo interno, con o sin la formación de hematoma interfascial. Objetivo: Evaluar los resultados de la evacuación del hematoma bajo guía ecográfica con o sin aplicación de plasma rico en plaquetas (PRP). Material y métodos: Se evaluaron retrospectivamente una serie de pacientes con cuadro de pierna de tenista con menos de un mes de evolución a los cuales se le realizó la aspiración del hematoma interfascial bajo guía ecográfica. A un grupo se les aplicó PRP interfascial y en la lesión y a otro grupo no. Se documentó la recidiva del hematoma, tiempo retorno deportivo y complicaciones. Resultados: Se evaluaron 17 pacientes con un seguimiento de 4,7 años (2,1 - 6,3) a nueve se les aplicó PRP (grupo A) y a ocho no se les aplicó PRP (grupo B). En el grupo B, cuatro pacientes (50%) presentaron una recidiva y dos de ellos (25%) una re-recidiva. El grupo A no presentó recidiva del hematoma. El tiempo de retorno al deporte fue para el grupo A de 9,6 semanas (7,8 ­ 12,2) y para el grupo B de 14,3 semanas (8,2 ­ 17,2). Dos pacientes (22,22%) del grupo A y cuatro pacientes (50%) del grupo B presentaron una fibrosis interfascial. Conclusión: Creemos que la evacuación ecoguiada del hematoma interfascial en pacientes con pierna de tenista, es un procedimiento válido para evitar complicaciones. La posterior aplicación del PRP interfacial y en el foco del desgarro disminuye el riesgo de recidiva del hematoma y acorta el tiempo de retorno al deporte. Nivel de evidencia: IV


Introduction: Tennis Leg, or the tear of the distal myotendinous junction of the inner calf muscle, with or without interfascial hematoma, is a frequently underdiagnosed injury. Objective: To evaluate the results of hematoma aspiration under ultrasound guidance, with or without the application of platelet-rich plasma (PRP). Material and methods: A number of patients with a clinical presentation of Tennis Leg were retrospectively evaluated. Those who presented with the case within the last 30 days were included. Ultrasound-guided aspiration of the interfascial hematoma was performed. Only one group received interfascial PRP and into the injury, while the other group did not. Recurrence of the hematoma, return-to-sport time and complications were documented. Results: Seventeen patients were evaluated with an average follow-up time of 4.7 years (2.1 - 6.3). Nine patients (group A) received a PRP injection whereas 8 (group B) did not. In group B, 4 patients (50%) presented with a recurrence of the hematoma and 2 patients (25%) with a re-recurrence of such lesion. On the other hand, group A did not experience a recurrence of the hematoma. On average, the return-to-sport time was 9.6 weeks (7.8 - 12.2) for group A and 14.3 weeks (8.2 - 17.2) for group B. Finally, 2 patients (22.22%) in group A and 4 patients (50%) in group B presented with interfascial fibrosis. Conclusion: We believe that ultrasound-guided aspiration of the interfascial hematoma in Tennis Leg is a fundamental procedure. The application of interfascial PRP and into the tear, lowers the risk of recurrence and reduces the return-to-sport time. Level of evidence: IV


Subject(s)
Athletic Injuries , Muscle, Skeletal/injuries , Platelet-Rich Plasma , Hematoma , Leg Injuries
9.
Rev. bras. med. esporte ; 24(6): 418-421, Nov.-Dec. 2018. tab, graf, ilus
Article in English | LILACS | ID: biblio-977843

ABSTRACT

OBJECTIVE: To analyze fibrous scar tissue inhibition capacity with the use of losartan, hydrocortisone and acetylsalicylic acid. METHOD: The sample consisted of 120 male heterogeneic Wistar rats with a muscle laceration model. The rats were divided into four groups of 30 animals each: control group, losartan group, ASA group and hydrocortisone group. The animals were anesthetized and a 2.5 cm longitudinal incision was made in the left thoracolumbar paravertebral region. The muscles were subjected to a Grade III lesion caused by applying Kelly hemostatic forceps for 60 seconds, followed by sectioning with scissors. The skin was sutured with 3-0 nylon monofilament thread. The animals were placed in individual cages with plenty of food and water. The losartan group received losartan diluted in water at a dose of 0.1 mg/mL (10 mg/kg/day), the ASA Group received a 3 mg/mL ASA solution (300 mg/kg/day), and the hydrocortisone group received a 0.2 mg/mL hydrocortisone solution (20 mg/kg/day). RESULTS: The control, losartan, hydrocortisone and aspirin groups had a fibrotic area of 0.95 ± 0.35 mm, 0.55 ± 0.34 mm, 0.93 ± 0.33 mm, and 0.66 ± 0.36 mm, respectively. We observed a significantly smaller fibrotic area in the losartan group compared to the control (p=0.01) and hydrocortisone (p=0.01) groups. There were no significant differences among the other groups. CONCLUSION: The healing of striated skeletal muscle produced less fibrous scar tissue when exposed to losartan in comparison to the control group or the hydrocortisone group. Level of Evidence I; Randomized double-blind placebo-controlled study.


OBJETIVO: Analisar a capacidade de inibição de formação de tecido cicatricial fibroso com losartana, hidrocortisona e AAS. MÉTODOS: A amostra consistiu em 120 ratos Wistar heterogênicos machos com modelo de laceração muscular. Os ratos foram distribuídos em quatro grupos de 30 animais: grupo controle, grupo losartana, grupo AAS e grupo hidrocortisona. Os animais foram anestesiados e submetidos a uma incisão em sentido longitudinal de 2,5 cm de extensão na região paravertebral toracolombar esquerda, e os músculos sofreram uma lesão grau III com pinça hemostática de Kelly durante 60 segundos e posterior secção com tesoura. A pele foi suturada com nylon monofilamentar 3-0. Os animais foram colocados em gaiolas individuais, com água e alimento à vontade. O grupo losartana recebeu losartana diluída em água na dose de 0,1 mg/ml (10 mg/kg/dia), o grupo AAS recebeu solução de AAS 3 mg/ml (300 mg/kg/dia), o grupo hidrocortisona recebeu solução de hidrocortisona 0,2 mg/ml (20 mg/kg/ dia). RESULTADOS: Os grupos controle, losartana, hidrocortisona e AAS apresentaram área fibrótica de0,95 ± 0,35 mm, 0,55 ± 0,34 mm, 0,93 ± 0,33 mm, 0,66 ± 0,36 mm, respectivamente. Observou-se área fibrótica significativamente menor do grupo losartana em comparação com o grupo controle (p = 0,01) e hidrocortisona (p = 0,01). Nos demais grupos não houve diferença significativa. CONCLUSÃO: A cicatrização do músculo estriado esquelético produziu menos tecido cicatricial fibroso quando exposto à losartana do que quando comparado com o grupo controle ou o grupo hidrocortisona. Nível de Evidência I; Estudo duplo-cego randomizado controlado por placebo.


OBJETIVO: Analizar la capacidad de inhibición de formación de tejido cicatricial fibroso con losartán, hidrocortisona y AAS (ácido acetilsalicílico). MÉTODOS: La muestra consistió en 120 ratas Wistar heterogéneas machos con modelo de laceración muscular. Las ratas fueron distribuidas en cuatro grupos de 30 animales: grupo control; grupo losartán; grupo AAS y grupo hidrocortisona. Los animales fueron anestesiados y sometidos a una incisión longitudinal de 2,5 cm de extensión en la región paravertebral toracolumbar izquierda y los músculos sufrieron una lesión de grado III con pinza hemostática de Kelly durante 60 segundos y posterior sección con tijera. La piel se suturó con monofilamento de nylon 3-0. Los animales fueron dispuestos en jaulas individuales con abundante comida y agua. El grupo losartán recibió losartán diluido en agua a una dosis de 0,1 mg/ml (10 mg/kg/día), el grupo AAS recibió solución de AAS de 3 mg/ml (dosis 300 mg/kg/día), el grupo hidrocortisona recibió solución hidrocortisona de 0,2 mg/ml (20 mg/kg/día). RESULTADOS: Los grupos control, losartán, hidrocortisona y AAS mostraron área fibrótica de 0,95 ± 0,35 mm, 0,55 ± 0,34 mm, 0,93 ± 0,33 mm, 0,66 ± 0,36 mm, respectivamente. Se observó área fibrótica significativamente menor del grupo losartán en comparación con el grupo control (p = 0,01) e hidrocortisona (p = 0,01). En los demás grupos no hubo diferencias significativas. CONCLUSIÓN: La cicatrización del músculo estriado esquelético produjo menos tejido cicatricial fibroso cuando fue expuesto a losartán que cuando fue comparado con el grupo control o el grupo hidrocortisona. Nivel de Evidencia I; Estudio doble ciego aleatorio controlado por placebo.


Subject(s)
Animals , Male , Regeneration/drug effects , Muscle, Skeletal/injuries , Losartan/administration & dosage , Losartan/pharmacology , Fibrosis/drug therapy , Hydrocortisone/administration & dosage , Hydrocortisone/pharmacology , Aspirin/administration & dosage , Aspirin/pharmacology , Analysis of Variance , Transforming Growth Factor beta , Treatment Outcome , Rats, Wistar , Recovery of Function , Animal Experimentation
10.
Int. j. morphol ; 36(4): 1210-1215, Dec. 2018. tab, graf
Article in Spanish | LILACS | ID: biblio-975684

ABSTRACT

El entrenamiento de fuerza, especialmente con alta intensidad de carga, permite aumentar la fuerza y trofismo muscular, pero también se asocia a daño muscular inducido por ejercicio (DMIE). Una nueva modalidad de entrenamiento, combina una baja intensidad de carga con la restricción parcial del flujo sanguíneo (RPFS) alrededor del músculo, siendo prometedor en cuanto el desarrollo de la fuerza y trofismo muscular. El objetivo del estudio fue comparar el rendimiento de fuerza máxima de los músculos cuádriceps e isquiotibiales (FM-Q y FM-I) y marcadores de daño muscular (CK) e inflamación sistémica (PCRus) entre un entrenamiento de baja intensidad de carga con RPFS, versus uno de alta y otro de baja intensidad de carga sin RPFS en jóvenes físicamente activos durante cuatro semanas de entrenamiento. Veintitrés participantes midieron la FM-Q y FM-I previo y al término de la intervención; además, antes del inicio de la primera sesión, y antes y después del término de la última sesión se midió la CK y PCRus. En los tres tipos de entrenamiento se produjeron aumentos equivalentes en la fuerza máxima, a excepción de la FM-Q del entrenamiento con baja intensidad sin RPFS. Solo en el entrenamiento con RPFS la CK y PCRus se modifican al finalizar la intervención, y aun cuando el estrés miocelular parece ser más alto que en los otros tipos de entrenamiento, no indicaría daño muscular.


Strength training, especially with high load intensity, allows increasing muscle strength and trophism, but it is also associated with exercise-induced muscle damage (EIMD). A new training modality, a combination of loading with the partial restriction blood flow (PRBF) around the muscle, being promising in the development of strength and muscular trophism. The aim of the study was to compare the maximum strength (MS) performance of quadriceps and hamstrings (MS-Q and MS-I) and muscle damage biomarkers (Creatine Kinase, CK) and systemic inflammation (high sensitivity - CRP, hs-CRP) between a low intensity load training with PRBF, versus one high and another low load intensity without PRBF in physically active youngsters during four weeks of training. Twenty-three participants measured MSQ and MS-I and the intervention term. In addition, before the start of the first session, before and after the end of the last session, CK and hsCRP were measured. In the three types of training the equivalent benefits in MS are produced, an exception of the MS-Q of low intensity training without PRBF. Only in the training with PRBF, the CK and hsCPR are modified at the end of the intervention, and even though the myocellular stress seems to be higher than in the other types of training, it would not indicate muscle damage.


Subject(s)
Humans , Male , Young Adult , Exercise/physiology , Muscle, Skeletal/injuries , Muscle Strength/physiology , Regional Blood Flow/physiology , C-Reactive Protein , Biomarkers , Muscle, Skeletal/physiopathology , Muscle, Skeletal/blood supply , Inflammation Mediators , Creatine Kinase
11.
Rev. bras. cineantropom. desempenho hum ; 20(2): 190-200, Mar.-Apr. 2018. tab, graf
Article in English | LILACS | ID: biblio-958356

ABSTRACT

Abstract A specific drop jumps (DJs) protocol (using 100 jumps) has been largely used to induce muscle damage. However, it failed to show relevant drop in performance in well-trained individuals. Trained subjects may require a protocol with greater volume to induce decrease of muscle performance. The aim of this study was to assess muscle performance after two DJs damaging protocols with different volumes in well-trained individuals. Eighteen strength and/or power-trained males (4.92 ± 2.78 years of training experience) were randomly assigned into one of two groups: DJ100 (five sets of 20 DJs) or DJ140 (seven sets of 20 DJs), with 2-min of rest interval. DJs were performed from a 60-cm box. After landing, the volunteers performed a maximal vertical rebound jump. Muscle swelling increased significantly on both DJ100 and DJ140 (p < 0.001). Maximal isometric torque (MIT) decreased significantly on both DJ100 (p = 0.005) and DJ140 (p < 0.001). MIT showed no between-group difference on pre-assessment (p = 0.815). However, on post-assessment, MIT was significantly lower on DJ140 than DJ100 (p = 0.043). Countermovement jump (CMJ) decreased significantly on DJ140 (p = 0.001), but not on DJ100 (p = 0.802). There was no between-group difference on pre-assessment (p = 0.978). However, on post-assessment, CMJ was significantly lower on DJ140 than DJ100 (p = 0.038). DJ140 induced greater drop in isometric strength than DJ100 and only DJ140 significantly reduced jump performance. These results demonstrated that well-trained individuals require a great volume of DJs to reduce substantially muscle performance.


Resumo Um protocolo específico de Drop Jumps (DJs), com 100 saltos, tem sido amplamente utilizado para induzir o dano muscular. Entretanto, este protocolo tem falhado em mostrar uma queda relevante em indivíduos treinados. Objetivou-se avaliar o desempenho muscular após dois protocolos de DJs com diferentes volumes em indivíduos treinados. Dezoito homens treinados em força e/ou potência (4,92 ± 2,78 anos de treinamento) foram aleatoriamente designados em um dos dois grupos: DJ100 (cinco séries de 20 DJs) ou DJ140 (sete séries de 20 DJs), com 2 minutos entre as séries. Os DJs foram executados de uma caixa de 60 cm de altura. Após a aterrisagem, os voluntários executaram um salto vertical máximo. O inchaço muscular aumentou significativamente em ambos os grupos (p < 0,001). O torque isométrico máximo (TIM) reduziu significativamente tanto no DJ100 (p = 0,005) quanto no DJ140 (p < 0,001). O TIM não apresentou diferenças entre grupos no momento pré (p = 0,815). Entretanto, no momento pós, o TIM foi significativamente inferior no DJ140 em relação ao DJ100 (p = 0,043). O salto com contra movimento (SCM) reduziu significativamente no DJ140 (p = 0,001), mas não no DJ100 (p = 0,802). No momento pós, o SCM foi significativamente inferior no DJ140 em relação ao DJ100. O DJ140 induziu uma queda maior na força isométrica em relação do DJ100, e somente o DJ140 reduziu significativamente o desempenho no salto. Esses resultados demonstraram que indivíduos bem treinados requerem um grande volume DJs para reduzir substancialmente o desempenho muscular.


Subject(s)
Humans , Male , Adult , Physical Education and Training/methods , Muscle, Skeletal/injuries , Athletic Performance , Exercise Test
12.
Rev. chil. ortop. traumatol ; 59(1): 10-15, mar. 2018. ilus, graf
Article in Spanish | LILACS | ID: biblio-910114

ABSTRACT

OBJETIVOS: Evaluar macroscópica e histológicamente la cicatrización muscular utilizando Dexametasona (DEX) o Traumeel (TRM), en un modelo experimental animal. MATERIAL Y MÉTODOS: Estudio experimental en 45 ratones BKS. Se seccionó transversal y completamente el cuádriceps derecho en todos los animales. Se definieron 3 grupos de estudio de 15 ratones cada uno, un grupo control, un grupo tratado con Dexametasona y uno con Traumeel. Los animales fueron sacrificados a las 1,2 y 4 semanas después del procedimiento y se les extrajo ambos cuádriceps (derecho como intervención e izquierdo como control) y luego fueron analizados macroscópica e histológicamente por un patólogo calificado, de manera ciega. Los datos se analizaron estadísticamente con el test de Kruskal - Wallis (p < 0,05), utilizando el programa Stata V12.1. RESULTADOS: Macroscopía: A la semana, en todos los grupos se evidenció ausencia de cicatrización con gap persistente. A la segunda semana, se evidencia cicatrización inicial sin gap en todos los grupos. A las 4 semanas todas las muestras estaban cicatrizadas. HISTOLOGÍA: La administración de Dexametasona disminuye el infiltrado inflamatorio y aumenta las fibras regenerativas, pero induce mayor fibrosis y pérdida de masa muscular. La adición de Traumeel aumenta la cantidad de fibras regenerativas, pero incrementa el infiltrado inflamatorio. CONCLUSIONES: A las 4 semanas ninguno de los grupos de estudio presentó regeneración muscular completa, con resultados macroscópicos e histológicos variables.


OBJETIVES: To macroscopically and histologically evaluate a muscle strain healing model, using Dexamethasone and Traumeel. MATERIALS AND METHODS: Experimental study in 45 BKS mice. 3 groups of 15 mice were defined: control group, Dexamethasone treated group and Traumeel treated group. The animals were sacrificed at the 1st, 2nd and 4th week, both quadriceps were resected (right as intervention and left as control) and then analyzed macroscopically and histologically by a qualified and blinded pathologist. Results were analyzed statistically using Kruskal - Wallis test (p<0.05). RESULTS: Macroscopy: the first week, all groups showed absence of healing with persistent gap. At the 2nd week, evidence of initial healing without gap in all groups. By week 4, all samples were healed. HISTOLOGY: Dexamethasone decreased the inflammatory infiltration and increased the regenerative fibers, but induced a higher fibrosis and loss of muscle mass. Traumeel increased the amount of regenerative fibers and the inflammatory infiltration. DISCUSSION: The results of our study fail to define a definitive posture. We observed that Traumeel actually increases the amount of regenerative fibers and contrary to the literature, it increases the inflammatory infiltrate. On the other hand, Dexamethasone showed similar results in both regenerative fibers, fatty infiltration and muscle mass, but with increased necrosis. CONCLUSIONS By the 4th week none of the groups showed complete muscle regeneration with macroscopic and histological variable results.


Subject(s)
Animals , Male , Mice , Dexamethasone/administration & dosage , Minerals/administration & dosage , Muscle, Skeletal/injuries , Muscular Diseases/drug therapy , Plant Extracts/administration & dosage , Disease Models, Animal , Muscle, Skeletal/drug effects , Muscle, Skeletal/pathology , Muscular Diseases/pathology , Quadriceps Muscle , Rupture , Time Factors , Wound Healing/drug effects
13.
Rev. chil. radiol ; 24(1): 22-33, mar. 2018. tab, graf, ilus
Article in Spanish | LILACS | ID: biblio-959570

ABSTRACT

Un gran segmento de la población participa en actividades deportivas. Las lesiones musculares corresponden a aproximadamente un tercio de las lesiones deportivas. Las demandas recreacionales y profesionales de la sociedad moderna exigen un diagnóstico precoz y preciso, para un adecuado tratamiento y seguimiento, dadas las implicancias económicas y mediáticas, especialmente en deportistas de elite. La imagenología tiene un rol fundamental en la evaluación de estas lesiones. Permite evaluar localización, extensión, severidad y estimar pronóstico, así como también el seguimiento para determinar el retorno deportivo. En este artículo se revisa la anatomía microscópica y macroscópica muscular, la fisiología, los tipos de lesiones y su representación en imágenes, tanto en ultrasonido (US), como en resonancia magnética (RM). Se mencionan distintas clasificaciones descritas en la literatura y se propone una nueva nomenclatura y descripción, basada principalmente en la anatomía muscular, la localización y cuantificación de las lesiones.


A large segment of the population participates in sporting activities. Muscle injuries account for approximately one-third of the injuries. The recreational and professional demands of modern society require an early and precise diagnosis of these, for an adequate treatment and follow-up, given the economic and media implications, especially in elite athletes1. Imaging plays a fundamental role in the evaluation of these lesions. It allows evaluation location, extent, severity and estimations of prognosis, as well as the follow-up to determine the return to sport. This article reviews the microscopic and macroscopic muscle anatomy, the physiology, types of lesions and their representation in images, both in ultrasound (US) and magnetic resonance (MRI). Different classifications described in the literature are mentioned and a nomenclature and description is proposed, based mainly on the muscle anatomy, localization and type of injury.


Subject(s)
Humans , Athletic Injuries/pathology , Athletic Injuries/diagnostic imaging , Muscle, Skeletal/injuries , Muscle, Skeletal/diagnostic imaging , Athletic Injuries/physiopathology , Magnetic Resonance Imaging , Tomography, X-Ray Computed , Ultrasonography
14.
Braz. j. med. biol. res ; 51(11): e7702, 2018. graf
Article in English | LILACS | ID: biblio-951726

ABSTRACT

When exercises are done in intense or exhaustive modes, several acute biochemical mechanisms are triggered. The use of cryotherapy as cold-water immersion is largely used to accelerate the process of muscular recovery based on its anti-inflammatory and analgesic properties. The present study aimed to study the biochemical effects of cold-water immersion treatment in mice submitted to exercise-induced exhaustion. Swiss albino mice were divided into 4 treatment groups: control, cold-water immersion (CWI), swimming exhaustive protocol (SEP), and SEP+CWI. Treatment groups were subdivided into times of analysis: 0, 1, 3, and 5 days. Exhaustion groups were submitted to one SEP session, and the CWI groups submitted to one immersion session (12 min at 12°C) every 24 h. Reactive species production, inflammatory, cell viability, and antioxidant status were assessed. The SEP+CWI group showed a decrease in inflammatory damage biomarkers, and reactive species production, and presented increased cell viability compared to the SEP group. Furthermore, CWI increased acetylcholinesterase activity in the first two sessions. The present study showed that CWI was an effective treatment after exercise-induced muscle damage. It enhanced anti-inflammatory response, decreased reactive species production, increased cell viability, and promoted redox balance, which could decrease the time for the recovery process.


Subject(s)
Animals , Male , Rabbits , Physical Conditioning, Animal/adverse effects , Physical Conditioning, Animal/physiology , Cryotherapy/methods , Muscle, Skeletal/physiopathology , Muscle, Skeletal/injuries , Immersion/physiopathology , Acetylcholinesterase/analysis , Swimming/injuries , Thiazoles , Time Factors , Cell Survival/physiology , Reproducibility of Results , Reactive Oxygen Species/analysis , Cold Temperature , Fluoresceins/analysis , Myositis/prevention & control , Antioxidants/analysis
15.
Einstein (Säo Paulo) ; 16(1): eAO4137, 2018. tab, graf
Article in English | LILACS | ID: biblio-891463

ABSTRACT

Abstract Objective To analyze the combined effects of the silk protein sericin and swimming exercise on histomorphometry of the plantar muscle in Wistar rats. Methods Forty adult rats were randomly allocated into 5 groups comprising 8 animals each, as follows: Control, Injury, Sericin, Swim, and Swim plus Sericin. Three days after crushing of the sciatic nerve the rats in the Swim and Swim plus Sericin Groups were submitted to swimming exercise for 21 days. Rats were then euthanized and the plantar muscle harvested and processed. Results Cross-sectional area, peripheral nuclei and muscle fiber counts, nucleus/fiber ratio and smallest muscle fiber width did not differ significantly between groups. Morphological analysis revealed hypertrophic fibers in the Swim Group and evident muscle damage in the Swim plus Sericin and Injury Groups. The percentage of intramuscular collagen was apparently maintained in the Swim Group compared to remaining groups. Conclusion Combined treatment with sericin and swimming exercise did not improve muscle properties. However, physical exercise alone was effective in maintaining intramuscular connective tissue and preventing progression of deleterious effects of peripheral nerve injury.


RESUMO Objetivo Analisar o efeito da proteína sericina associada ao exercício físico de natação na histomorfometria do músculo plantar de ratos Wistar. Métodos Foram utilizados 40 ratos adultos divididos aleatoriamente em 5 grupos, com 8 animais cada: Controle, Lesão, Sericina, Natação, Natação e Sericina. Três dias após a compressão do nervo isquiático, os Grupos Natação e Exercício e Sericina foram submetidos ao exercício físico de natação durante 21 dias. Após, os animais foram sacrificados, e o músculo plantar foi processado. Resultados Não houve diferença da área da secção transversa entre os grupos, quantidade de núcleos periféricos, quantidade de fibra, relação núcleo/fibra e diâmetro menor. A análise morfológica revelou que no Grupo Natação ocorreu hipertrofia das fibras, assim como nos Grupos Exercício e Sericina e Lesão, o dano muscular foi evidente. O percentual de conjuntivo intramuscular parece ter sido mantido no Grupo Exercício em relação aos demais grupos. Conclusão A associação da proteína sericina e exercício físico de natação não foi eficiente na melhora das propriedades musculares, embora a aplicação do exercício físico tenha sido eficiente na manutenção do conjuntivo intramuscular, e no não agravamento dos efeitos deletérios consequentes da lesão nervosa periférica.


Subject(s)
Animals , Rats , Physical Conditioning, Animal/physiology , Swimming/physiology , Muscle, Skeletal/innervation , Lower Extremity/innervation , Sericins/pharmacology , Random Allocation , Rats, Wistar , Muscle, Skeletal/injuries , Muscle, Skeletal/pathology , Lower Extremity/injuries , Lower Extremity/pathology , Disease Models, Animal , Nerve Crush
16.
Article in Spanish | LILACS, BINACIS | ID: biblio-995389

ABSTRACT

Introducción: El recto abdominal (RA), es un musculo par, acintado, que tiene como principales funciones la flexión del tronco y la estabilidad del Core. Su desgarro se asocia al deporte de elite y lanzadores, mayormente vinculado con el tenis y su servicio según publicaciones. En voleibol se repiten ciclos de hiperextensión del tronco con sobrecarga excéntrica y consecuente hipertrofia asimétrica del RA contralateral al brazo dominante, asiento de la lesión muscular. Materiales y métodos: Se realizó un estudio descriptivo, retrospectivo de una serie de motivos de consulta de jugadores de la Selección Nacional Argentina masculina mayor de voleibol durante el período comprendido entre 2015 y 2017. Se clasificaron las lesiones en función del retorno al deporte según Paús V. y Torrengo. Los deportistas con desgarro de RA, fueron agrupados evaluando las variables: brazo dominante, RA lesionado, tipo de lesión muscular, gesto deportivo involucrado, situación de competencia durante la lesión, lesión abdominal previa. Resultados: Se evaluaron 386 motivos de consulta, los jugadores centrales fueron los que más consultaron, en el contexto general de lesiones se clasificaron los 10 motivos principales de consulta, las lesiones musculares funcionales (contracturas) fueron las más frecuentes (n97, 25%), el desgarro de RA fue la lesión muscular estructural predominante por encima del gastrocnemio. 6 casos de lesión aguda y 1 caso de recurrencia, la mayoría durante el gesto de ataque y en competencia. Conclusión: De lo analizado en los registros la lesión muscular representó el 42% del total de las lesiones, el desgarro tiene predominio en el recto abdominal representando el 32% de total de las lesiones musculares estructurales. Nivel de evidencia: IV


Introduction: The rectus abdominis (RA), is a pair, curved muscle, whose main functions are trunk flexion and Core stability. His strain is associated with the sport of elite and pitchers, mostly linked to tennis and its service according to publications. In volleyball, cycles of hyperextension of the trunk with eccentric sebrecharge and consequent asymmetric hypertrophy of the RA contralateral to the dominant arm, seat of the muscle injury, are repeated. Materials and methods: A descriptive, retrospective study of a series of reasons for consultation of players of the Argentine National Men's Volleyball Team during the period between 2015 and 2017 was carried out. The injuries were classified according to the return to sport criteria by Páus V. and Torrengo F. The athletes with RA strain were grouped evaluating following variables: Dominant arm, injured RA, type of muscle injury, sports gesture involved, competition situation at injury time, previous abdominal lesion. Results: We evaluated 386 reasons for consultation, the central players were the most consulted, in the general context of injuries were classified the 10 main reasons for consultation, muscle functional injuries (contractures) were the most frequent (n97, 25%), the RA strain was the predominant structural muscle lesion above the gastrocnemius. 6 case of acute injury and 1 case of recurrence. most during the attack gesture and in competition. Conclusion: From the analyzed in the registers the muscular injury represented 42% of the total of the injuries, the strain has predominance in the rectus abdominus representing 32% of the total of the muscular structural injuries. Level of evidence: IV


Subject(s)
Adolescent , Adult , Athletic Injuries , Rectus Abdominis/injuries , Muscle, Skeletal/injuries , Volleyball/injuries , Incidence
17.
Rev. bras. ortop ; 52(6): 743-747, Nov.-Dec. 2017. graf
Article in English | LILACS | ID: biblio-899199

ABSTRACT

ABSTRACT Muscle injury is the most common injury during sport practice. It represents 31% of all lesions in soccer, 16% in track and field, 10.4% in rugby, 17.7% in basketball, and between 22% and 46% in American football. The cicatrization with the formation of fibrotic tissue can compromise the muscle function, resulting in a challenging problem for orthopedics. Although conservative treatment presents adequate functional results in the majority of the athletes who have muscle injury, the consequences of treatment failure can be dramatic, possibly compromising the return to sport practice. The biarticular muscles with prevalence of type II muscle fibers, which are submitted to excentric contraction, present higher lesion risk. The quadriceps femoris is one example. The femoris rectus is the quadriceps femoris muscle most frequently involved in stretching injuries. The rupture occurs in the acceleration phase of running, jump, ball kicking, or in contraction against resistance. Although the conservative treatment shows good results, it is common that the patient has lower muscle strength, difficulty in return to sports, and a permanent and visible gap. Surgical treatment can be an option for a more efficient return to sports.


RESUMO As lesões musculares são uma das mais comuns ocorridas por traumas nos esportes. Elas constituem 31% de todas as lesões no futebol, 16% no atletismo, 10,4% no rúgbi, 17,7% no basquete e de 22% a 46% no futebol americano. Representam um problema desafiador na traumatologia, já que os músculos lesados se curam vagarosamente e com eventual recuperação incompleta da função. Embora o tratamento conservador resulte em bons resultados funcionais na maioria dos atletas com lesão muscular, as consequências da falha do tratamento podem ser dramáticas, possivelmente atrasam o retorno ao esporte. Os músculos mais frequentemente envolvidos são os biarticulares ou aqueles com maior complexidade estrutural (por exemplo, adutor longo), que são submetidos a contração excêntrica e contêm principalmente fibras de contração rápida (tipo 2). Um representante desse grupo é o quadríceps femoral, que se constitui pelos músculos reto femoral, vasto medial, vasto intermédio e vasto lateral. O reto femoral é o músculo do quadríceps mais envolvido nas lesões por estiramento. É mais lesado nas fases de aceleração do "tiro", salto de explosão, chute da bola ou quando há uma contração contra resistência. Mesmo que o tratamento conservador apresente bons resultados, é comum que o paciente tenha diminuição da força muscular, dificuldade de retorno ao esporte e gap permanente e visível. O tratamento cirúrgico pode ser uma opção para um retorno mais eficiente ao esporte.


Subject(s)
Adult , Middle Aged , Athletic Injuries , Muscle, Skeletal/injuries , Muscles , Orthopedic Procedures , Quadriceps Muscle/injuries
18.
Rev. bras. ortop ; 52(4): 373-382, July-Aug. 2017. tab, graf
Article in English | LILACS | ID: biblio-1042405

ABSTRACT

ABSTRACT Hamstring (HS) muscle injuries are the most common injury in sports. They are correlated to long rehabilitations and have a great tendency to recur. The HS consist of the long head of the biceps femoris, semitendinosus, and semimembranosus. The patient's clinical presentation depends on the characteristics of the lesion, which may vary from strain to avulsions of the proximal insertion. The most recognized risk factor is a previous injury. Magnetic resonance imaging is the method of choice for the injury diagnosis and classification. Many classification systems have been proposed; the current classifications aim to describe the injury and correlate it to the prognosis. The treatment is conservative, with the use of anti-inflammatory drugs in the acute phase followed by a muscle rehabilitation program. Proximal avulsions have shown better results with surgical repair. When the patient is pain free, shows recovery of strength and muscle flexibility, and can perform the sport's movements, he/she is able to return to play. Prevention programs based on eccentric strengthening of the muscles have been indicated both to prevent the initial injury as well as preventing recurrence.


RESUMO As lesões dos músculos isquiotibiais (IT) são as mais comuns do esporte e estão correlacionadas com um longo tempo de reabilitação e apresentam uma grande tendência de recidiva. Os IT são compostos pela cabeça longa do bíceps femoral, semitendíneo e semimembranoso. A apresentação clínica do paciente depende das características da lesão, que podem variar desde um estiramento até avulsões da inserção proximal. O fator de risco mais reconhecido é a lesão prévia. A ressonância magnética é o exame de escolha para o diagnóstico e classificação da lesão. Muitos sistemas de classificação têm sido propostos; os mais atuais objetivam descrever a lesão e correlacioná-la com o seu prognóstico. O tratamento das lesões é conservador, com o uso de medicações anti-inflamatórias na fase aguda, seguido do programa de reabilitação. As lesões por avulsão proximal têm apresentado melhores resultados com o reparo cirúrgico. Quando o paciente está sem dor, apresenta recuperação da força e do alongamento muscular e consegue fazer os movimentos do esporte, está apto para retornar à atividade física. Programas de prevenção, baseados no fortalecimento excêntrico da musculatura, têm sido indicados tanto para evitar a lesão inicial como a recidiva.


Subject(s)
Athletic Injuries , Muscle, Skeletal/injuries , Return to Sport
19.
Acta cir. bras ; 32(5): 369-375, May 2017. tab, graf
Article in English | LILACS | ID: biblio-837706

ABSTRACT

Abstract Purpose: To realize a morphological examination of the musculoskeletal tissue, assessing the effect of a contusion method for the production in rat gastrocnemius, comparing the inflammatory responses generated by different impacts. Methods: For the analysis of a contusion method, twelve female Wistar rats were distributed into four groups. The lesion was generated by 324 g of mass that was dropped from different predetermined heights for each group (30, 45, 60 and 70 cm). Results: In the analysis of musculoskeletal tissue, the response to injury varied according to the mass of the height drop onto the muscle. Only the group that was injured from 70 cm responded with uniform and severe inflammation, whereas the groups 30, 45 and 60 cm showed inflammation in some regions of the tissue with mild and moderate infiltrates. Conclusion: The method with the 324-gram mass dropped from a 70-cm height onto the gastrocnemius muscle of rats seems to be the most suitable for the production of muscle injury in these animals after 72 hours, showing an important inflammatory infiltrate.


Subject(s)
Animals , Female , Muscle, Skeletal/injuries , Contusions/pathology , Disease Models, Animal , Rats, Wistar , Muscle, Skeletal/pathology , Contusions/etiology , Equipment Design/instrumentation , Equipment Design/methods , Inflammation/pathology
20.
Rev. bras. ortop ; 52(1): 11-16, Jan.-Feb. 2017.
Article in English | LILACS | ID: biblio-844087

ABSTRACT

ABSTRACT Hamstring injuries are among the most frequent in sports. The high relapse rate is a challenge for sports medicine and has a great impact on athletes and sport teams. The treatment goal is to provide the athlete the same functional level as before the injury. Thus, functional rehabilitation is very important to the success of the treatment. Currently, several physical therapy modalities are used, according to the stage of the lesion, such as cryotherapy, laser therapy, therapeutic ultrasound, therapeutic exercise, and manual therapy. However, the evidence of the effectiveness of these modalities in muscle injuries is not fully established due to the little scientific research on the topic. This article presents an overview of the physiotherapy approach in the rehabilitation of hamstring muscle injuries.


RESUMO As lesões dos isquiotibiais estão entre as mais frequentes do esporte. A alta taxa de recidivas representa um desafio para a medicina esportiva e apresenta grande impacto para atletas e clubes esportivos. O objetivo do tratamento é proporcionar ao atleta o mesmo nível funcional anterior à lesão. Dessa forma, a reabilitação funcional é muito importante para o sucesso do tratamento. Atualmente, usam-se várias modalidades fisioterápicas de acordo com o estágio da lesão: crioterapia, laserterapia, ultrassom terapêutico, terapia manual e cinesioterapia. Entretanto, as evidências da eficácia dessas modalidades nas lesões musculares ainda não estão completamente estabelecidas, devido à baixa investigação científica sobre o tema. O presente artigo apresenta uma revisão sobre a abordagem fisioterápica na reabilitação das lesões musculares de isquiotibiais.


Subject(s)
Athletic Injuries , Muscle Stretching Exercises , Muscle, Skeletal/injuries , Physical Therapy Modalities
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