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Rev. argent. cir. plást ; 27(2): 86-89, 20210000. fig
Article in Spanish | LILACS, BINACIS | ID: biblio-1357903


El objetivo de este trabajo es normatizar el uso de la terapia de presión negativa de heridas complejas en neonatos. La iniciativa surge a partir de la negativa de nuestros proveedores locales de proporcionarnos el material del sistema VAC (cicatrización asistida por vacío), por temor a las posibles complicaciones por su uso en neonatos y escasa bibliografía al respecto. Se presentan 2 casos tratados en neonatos entre 2018 y 2021, y se acompaña de revisión bibliográfica encontrada, de diferente etiología. Con las conclusiones obtenidas, se pretende establecer al VAC como una herramienta terapéutica eficaz en neonatos, de igual manera que se aplica, en toda herida compleja que lo requiera, sin importar la edad del paciente

The goal of this work is to standardize the use of negative pressure therapy for complex wounds in newborns. The initiative arises from the refusal of our local suppliers to provide us with the VAC (vacuum-assisted healing) system material, for fear of possible complications from its use in newborns and little literature about it. There are 2 cases treated in neonates between 2018 and 2021, and it is accompanied by found bibliographic review of different etiology. With the conclusions obtained, it is intended to establish the VAC as an effective therapeutic tool in neonates, just as it is applied, in any complex wound that requires it, regardless of the age of the patient

Humans , Infant, Newborn , Wound Healing , Wounds and Injuries/therapy , Negative-Pressure Wound Therapy/methods , Wound Closure Techniques
Clinics ; 76: e2355, 2021. tab, graf
Article in English | LILACS | ID: biblio-1153933


OBJECTIVES: To evaluate the efficacy of autologous platelet-rich plasma (PRP) gel in the treatment of refractory pressure injuries and its effect on wound healing time and quality of life of patients. METHODS: A random number table method was used to group 102 patients with refractory pressure injuries into either a control group (CG) (51 cases) receiving negative pressure wound therapy (NPWT) or a study group (SG) (51 cases) receiving NPWT+PRP gel. RESULTS: The total efficacy rate in the SG (92.16%) was higher than that in the CG (76.47%) (p<0.05). The SG exhibited lower visual analog scale (VAS) scores and pressure ulcer scale for healing (PUSH) scores, smaller wound sizes and depths, and shorter wound healing times than the CG after 21 days of treatment (p<0.05). After 6 months of treatment, the SG scored higher than the CG on the psychological, physiological, social functions, and daily activity domains on the World Health Organization Quality of Life (WHOQOL-BREF) scale (p<0.05). The incidence of postoperative complications in the SG (13.73%) was not significantly different from that of the CG (7.84%) (p>0.05). CONCLUSION: In the treatment of refractory pressure injuries, PRP gel can accelerate wound healing, reduce wound pain, shorten the treatment cycle, regulate tissue inhibitor matrix metalloproteinase-1 (TIMP-1) and matrix metalloproteinase-9 (MMP-9) levels and the expression of specific proteins in granulation tissue, reduce the levels of the inflammatory factors interleukin-1β (IL-1β), IL-8, and tumor necrosis factor-α (TNF-α), and improve the quality of life of patients without increasing complications.

Humans , Pressure Ulcer , Platelet-Rich Plasma , Negative-Pressure Wound Therapy , Quality of Life , Wound Healing
Article in Chinese | WPRIM | ID: wpr-880432


Negative pressure wound therapy has become an important technology in the global field of wound care, and the development of this technology is inseparable from the development and application of negative pressure wound care products. Based on the characteristics of the negative pressure wound therapy products, this paper discusses the key contents that should be considered in the design and evaluation of the negative pressure wound protection products from the aspects of physical and chemical properties, biocompatibility, intended use and risk warning information, in order to provide reference for the development and technical review of such products.

Bandages , Negative-Pressure Wound Therapy
Rev. med. Risaralda ; 26(1): 92-96, ene.-jun. 2020. graf
Article in Spanish | LILACS, COLNAL | ID: biblio-1127007


Resumen Objetivo: Reportar un caso sobre el uso de la terapia de presión negativa como tratamiento alternativo en el manejo de una úlcera vascular arterial de miembros inferiores. Métodos: Por medio de la historia clínica, se revisó los registros previos de una paciente en un centro de atención médica de tercer nivel en Popayán, Colombia. Posteriormente, se realizó una revisión sistemática bibliográfica a través de las bases de datos de Pubmed, ScienceDirect y Scielo. Resultados: La terapia de presión negativa favoreció el proceso de cicatrización, permitiendo el cierre de la herida. Conclusiones: Actualmente, este sistema se considera un apoyo fundamental en el tratamiento de las heridas complejas, las cuales suponen un reto terapéutico importante.

Abstract Objective: To report a case about the use of the Negative-pressure wound therapy as an alternative treatment for arterial vascular ulcers presented in the lower limbs. Methods: The patient's records were reviewed based on her medical history in a tertiary referral care center in Popayan, Colombia. Subsequently, a systematic literature review was conducted through the Pubmed database, ScienceDirect, and Scielo. Results: The use of Negative-pressure wound therapy favored the lesion healing process. Conclusions: Nowadays, this system is considered as an essential treatment for complex wounds, which represent a major therapeutic challenge.

Humans , Female , Middle Aged , Ulcer , Lower Extremity , Negative-Pressure Wound Therapy , Pressure , Therapeutics , Wounds and Injuries , Tertiary Healthcare , Alkalies
Rev. bras. cir. cardiovasc ; 35(1): 50-57, Jan.-Feb. 2020. tab, graf
Article in English | LILACS | ID: biblio-1092468


Abstract Introduction: Negative pressure wound therapy (NPWT) has significantly improved outcomes in individuals with superficial and deep sternal wound dehiscence (SWD). We report our experience with NPWT to evaluate factors influencing effectiveness, duration of treatment and postoperative hospital stay. Methods: We reviewed 92 patients with postoperative SWD following a median sternotomy. Patients were divided into 2 groups: those with a superficial SWD (Group 1; 72, 78%) and those with a deep SWD (Group 2; 20, 28%). Group 1 was further divided into 3 subgroups based on NPWT duration. Results: In both groups, none of the preoperative characteristics examined showed a significant association with longer NPWT duration. In Group 2, there was a trend for postoperative bleeding and neurological complications to be associated with longer treatment duration. In the entire series, staph infection resulted a weak predictor of NPWT duration. In each Group 1 subgroup and in Group 2, treatment days were compared with duration of hospitalization until discharge. Mean post-NPWT hospital stay was 6 days in subgroup 1, 12 days in subgroup 2 and 20 days in subgroup 3 (P<0.0001). At a median 3-year follow-up, there were 4 late deaths, none related to wound complications. No cases of SWD recurrence were observed. Conclusion: Our results confirm the effectiveness of NPWT in SWD management, while excessive treatment duration might have a negative impact on the length of hospital stay. Further studies are needed to define an optimal use of NPWT protocol.

Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Negative-Pressure Wound Therapy , Staphylococcus aureus , Surgical Wound Infection , Retrospective Studies , Treatment Outcome , Sternotomy
Nigerian Medical Practitioner ; 78(1-2): 24-32, 2020.
Article in English | AIM, AIM | ID: biblio-1267991


Pressure ulcers are quite distressing, and they cut across all age groups. Aside from increasingmortality, it results in protracted hospital stay and an upsurge in the consumption of healthcare resourcesPressure ulcers are considered to be essentially preventable, but in order to prevent them it is important to identify the people most at risk and deliver timely preventative care. In case of severe acute respiratory distress syndrome (ARDS), as in coronavirus dis­ease 2019 (COVID-19) affected patients, prone position and invasive ventilation improve the clinical status of this group of patients. This form of therapy is associated with an increased risk of facial pressure ulcers. When pressure ulcer occurs, appropriate documentation of each ulcer and staging of the ulcer are essential for good wound assessment.Treatment involves, assessing the nutritional needs of the patient, management of infections, removal of necrotic tissue, maintenance of a moist environment for wound healing, and possibly surgery

Crush Injuries , Debridement , Negative-Pressure Wound Therapy , Nutritional Sciences , Pressure Ulcer
Rev. colomb. cir ; 35(4): 614-620, 2020. fig, tab
Article in Spanish | LILACS | ID: biblio-1147905


Introducción. La terapia de presión negativa es un recurso utilizado cada vez con mayor frecuencia en el manejo de heridas complejas en pediatría. El objetivo de este estudio fue describir la experiencia con esta terapia en diferentes situaciones clínicas. Métodos. Se llevó a cabo un estudio descriptivo retrospectivo en un grupo de pacientes pediátricos en quienes se utilizó la terapia de presión negativa entre el año 2010 y el 2015. Se analizaron las variables sociodemográficas, los diagnósticos que indicaron la terapia, el tiempo de uso, sus complicaciones y la mortalidad. Resultados. Se incluyeron 41 pacientes. La terapia se indicó en 39 casos con heridas localizadas en el abdomen, en uno con infección de los tejidos blandos perianales y en otro con una herida de esternotomía infectada. De las heridas abdominales, 14 fueron por complicaciones relacionadas con apendicitis aguda, 6 por enfermedades relacionadas con megacolon, 5 por obstrucción intestinal, 4 para el manejo de fístulas, 4 por enterocolitis necrosante del recién nacido, 3 por pancreatitis aguda y 3 por otras causas. El tiempo promedio de uso de la terapia fue de 7 días. Se presentaron fallas en el sistema de vacío en dos pacientes, pero no hubo complicaciones por el uso de la terapia. Dos pacientes fallecieron por complicaciones relacionadas con su enfermedad de base. Conclusión. La terapia de presión negativa es un recurso efectivo en el manejo de heridas complejas en la población pediátrica

Introduction. Negative pressure therapy is an increasingly used resource in the management of complex wounds in pediatrics. The objective of this study was to describe the experience with this therapy in different clinical situations. Methods. A retrospective descriptive study was conducted in a group of pediatric patients who received negative pressure therapy between 2010 and 2015. We analyzed the sociodemographic variables, the diagnoses that indi-cated the therapy, the time of use of the therapy, complications and mortality. Results. A total of 41 patients were included. Therapy was indicated in 39 cases with wounds located in the ab-domen, in one with infection of the perianal soft tissues, and in another with an infected sternotomy wound. Of the abdominal wounds, 14 were due to complications related to acute appendicitis, six due to diseases related to megacolon, five due to intestinal obstruction, four for the management of fistulas, four due to necrotizing enterocolitis of the newborn, three due to acute pancreatitis, and three due to other causes. The average time of use of the therapy was 7 days. Vacuum system failures occurred in two patients, but there were no complications from the use of therapy. Two patients died of complications related to their underlying disease.Conclusion. Negative pressure therapy is an effective resource in the management of complex wounds in the pediatric population

Humans , Negative-Pressure Wound Therapy , Pediatrics , Appendicitis , Enterocolitis, Necrotizing
Rev Assoc Med Bras (1992) ; 66(4): 430-436, 2020. tab, graf
Article in English | SES-SP, LILACS, SES-SP | ID: biblio-1136238


SUMMARY OBJECTIVE To investigate the clinical efficacy of cefazolin sodium pentahydrate combined with vacuum sealing drainage (VSD) in the treatment of open fracture complicated with soft tissue injury. METHODS Sixty-three patients with open fracture complicated with soft tissue injury were divided into observation (n = 33) and control (n = 30) groups. After surgical reduction, fixation, and repair of the fractures, the control group was treated with VSD for 10 days, and the observation group was treated with cefazolin sodium pentahydrate based on VSD for 10 days. The infection control time was recorded. After treatment, the pain of patients was evaluated. Before and after treatment, the serum levels of C-reactive protein (CRP), interleukin (IL)-6, IL-8, tumor necrosis factor α (TNF-α), cortisol, epinephrine, norepinephrine, and glucose were detected. After 6 months of treatment, the total effective rate of the treatment was evaluated. RESULTS The infection control time and Visual Analogue Scale score after treatment in the observation group were significantly lower than in the control group, respectively (P < 0.05). After the treatment, the serum levels of CRP, IL-6, IL-8, TNF-α, cortisol, epinephrine, norepinephrine, and glucose in each group were significantly lower than before the treatment (P < 0.05), and each index in observation was significantly lower than in the control group (P < 0.05). CONCLUSIONS In the treatment of open fractures complicated with soft tissue injury, cefazolin sodium pentahydrate combined with VSD can effectively reduce inflammation and stress, thus improving the treatment efficacy.

RESUMO OBJETIVO Investigar a eficácia clínica do cefazolin penta-hidrato de sódio combinado com drenagem por vedação a vácuo (VSD) no tratamento da fratura exposta complicada com lesão nos tecidos moles. MÉTODOS Sessenta e três doentes com fratura exposta complicada com lesões nos tecidos moles foram divididos em grupos de observação (n=33) e controle (n=30). Após redução cirúrgica, fixação e reparação da fratura, o grupo de controle foi tratado com VSD durante dez dias e o grupo de observação foi tratado com cefazolina penta-hidrato de sódio com base no VSD durante dez dias. O tempo de controle de infecção foi gravado. Após o tratamento, a dor dos doentes foi avaliada. Antes e após o tratamento, foram detectados os níveis séricos de proteína C-reativa (CRP), interleucina (IL)-6, IL -8, fator de necrose tumoral alfa (TNF-α), cortisol, epinefrina, norepinefrina e glicose. Após seis meses de tratamento, a taxa efetiva total de tratamento foi avaliada. RESULTADOS O tempo de controle da infecção e a pontuação da Escala Visual Analógica após o tratamento no grupo de observação foram significativamente inferiores ao do grupo de controle, respectivamente (P<0,05). Após o tratamento, os níveis séricos de CRP, IL-6, IL-8, TNF-α, cortisol, epinefrina, norepinefrina e glicose em cada grupo foram significativamente menores do que antes do tratamento, respectivamente (P<0,05), e cada índice de observação foi significativamente inferior ao do grupo de controle (P<0,05). CONCLUSÃO No tratamento da fratura exposta complicada com lesões nos tecidos moles, o cefazolin penta-hidrato de sódio combinado com VSD pode efetivamente reduzir a inflamação e o estresse, melhorando assim a eficácia do tratamento.

Humans , Cefazolin/therapeutic use , Soft Tissue Injuries , Negative-Pressure Wound Therapy , Fractures, Open/therapy , Anti-Bacterial Agents/therapeutic use , Wound Healing , Drainage , Treatment Outcome
Article in Chinese | WPRIM | ID: wpr-828249


OBJECTIVE@#To investigate the therapeutic effects of vacuum sealing drainage (VSD) combined with antibiotics in treating acute periprosthetic joint infection (PJI).@*METHODS@#From March 2012 to December 2018, there were 11 patients with acute PJI underwent debridement, VSD, antibiotics and retention of implant, including 7 males and 4 females, with an average age of 72.5 years old (ranged, 58 to 88 years old). There were 8 hips and 3 knees. Three patients had sinus tract.@*RESULTS@#There were 2 patients with negative culture result and 9 patients with positive culture result, including 5 cases of methicillin sensitive staphylococcus aureus, 2 cases of methicillin-resistant staphylococcus aureus (MRSA), 2 cases of staphylococcus epidermidis. The mean follow up duration was 28 months (ranged from 8 to 52 months). One case of infection around hip prosthesis failed to be debrided. The time of debridement and replacement of the calcar joint was 84 days. Debridement was successful in 10 cases. At the latest follow up, Harris score of patients with successful debridement of hip periprosthetic infection ranged from 74 to 93, with an average score of 84.1;Knee Society scores of patients with periprosthetic infection were 84, 84, 89.@*CONCLUSION@#For acute infection around the prosthesis within 1 month after knee replacement and 6 weeks after hip replacement, and for bleeding around the prosthesis with acute infection caused by anticoagulant drugs, satisfactory results can be obtained by debridement, VSD and sensitive antibiotics.

Aged , Aged, 80 and over , Anti-Bacterial Agents , Arthroplasty, Replacement, Hip , Debridement , Drainage , Female , Hip Prosthesis , Humans , Male , Methicillin-Resistant Staphylococcus aureus , Middle Aged , Negative-Pressure Wound Therapy , Prosthesis-Related Infections , Retrospective Studies , Treatment Outcome
Article in Chinese | WPRIM | ID: wpr-827240


OBJECTIVE@#To explore the clinical effect of vacuum sealing drainage (VSD) technique and Ointment in the treatment of foot skin defect.@*METHODS@#From November 2017 to April 2019, 21 patients (21 feet) with foot skin defect were treated with VSD technique and Ointment. There were 17 males and 4 females, aged from 24 to 60 years old with an average of (37.8±11.2) years, 9 cases caused by traffic accident injury, 6 cases by heavy injury, 6 cases by falling injury. The time from injury to operation was for 3 to 36 (8.6±7.2) h, and the area of foot skin defect was for 20.35 to 83.43(47.2±19.5) cm. All patients underwent debridement or phaseⅠtemporary fixation in emergency, and three-dimensional imagingof the foot was performed by using Mimics software, and the defect area was rendered. The quality of wound healing and complications were observed, and the clinical effect was evaluated by Maryland foot function score.@*RESULTS@#All the 21 patients were followed up for 7 to 17 (10.8±2.7) months. There was no infection or nonunion in all patients. At the final follow-up, the skin margin of the healing site grew tightly, the skin was elastic, the texture was tough, the appearance was no obvious carbuncle. The time of wound healing was for 18 to 63 (41.2±13.3) days. Eight patients underwent stageⅡfixation or/and fusion, and all incisions healed by stageⅠ. According to Maryland's foot scoring, 9 cases got excellent results, 11 good, and 1 middle.@*CONCLUSION@#VSD can effectively remove the necrotic tissue of the wound, provide a smooth drainage of the wound, combine with Ointment to prevent infection and promote the rapid growth of granulation tissue, whose whole treatment cycle was short, the wound healing site was highquality, the limb function was good, and the clinical effect was satisfactory.

Adult , Drainage , Female , Humans , Male , Middle Aged , Negative-Pressure Wound Therapy , Skin Transplantation , Soft Tissue Injuries , General Surgery , Treatment Outcome , Young Adult
Rev. argent. coloproctología ; 30(4): 104-113, dic. 2019. ilus, tab, graf
Article in Spanish | LILACS | ID: biblio-1096799


Introducción: Los pacientes que se presentan con cuadros de peritonitis de origen diverticular (estadios Hinchey III o IV) en un contexto de sepsis severa con inestabilidad hemodinámica (shock séptico) la realización de anastomosis primaria presenta una alta tasa de dehiscencia anastomótica y mortalidad operatoria, aconsejándose la realización de una resección y abocamiento a la manera de Hartmann. Sin embargo, la alta tasa de complicaciones relacionadas a la confección del ostoma, la complejidad de la cirugía de restauración del tránsito intestinal, asociado a que entre el 40 % y el 60 % de los Hartmann no se reconstruyen, ha estimulado a que se intenten otras variables de resolución para esta compleja y grave patología. Diversas publicaciones en los últimos años han propuesto la táctica de "cirugía del control del daño" con el objeto de disminuir la morbimortalidad de estos gravísimos cuadros sépticos y a su vez reducir la tasa de ostomías. El objetivo de este trabajo es presentar nuestra experiencia inicial con esta modalidad de manejo de la peritonitis diverticular Hinchey III/IV sepsis severa e inestabilidad hemodinámica (shock séptico) y realizar una revisión bibliográfica del tema. Material y método: Estudio observacional, descriptivo, de series de casos. Entre noviembre de 2015 y diciembre de 2016. Servicio de coloproctología del complejo médico hospitalario Churruca-Visca de la ciudad de Buenos Aires y práctica privada de los autores. Se utilizó la técnica de laparotomía abreviada y cierre temporal del abdomen mediante un sistema de presión negativa. Resultados: En el periodo descripto se operaron 17 pacientes con peritonitis generalizada purulenta o fecal de origen diverticular. Catorce casos fueron Hinchey III (82,36%) y 3 casos Hinchey IV (17,64%). En 3 casos se observó inestabilidad hemodinámica en el preoperatorio o intraoperatorio. Todos ellos correspondientes al estadio IV de Hinchey. Se describen los 3 casos tratados mediante esta táctica quirúrgica. Discusión: La alta tasa de morbimortalidad de este subgrupo de pacientes incentivó a diversos grupos quirúrgicos a implementar la técnica de control del daño, permitiendo de esta manera estabilizar a los pacientes hemodinámicamente y en un segundo tiempo evaluar la reconstrucción del tránsito intestinal. En concordancia con estas publicaciones, dos de nuestros pacientes operados con esta estrategia, pudieron ser anastomosados luego del segundo lavado abdominal. Conclusión: En pacientes con peritonitis diverticular severa asociado a shock séptico el concepto de laparotomía abreviada con control inicial del foco séptico, cierre temporal del abdomen con sistema de presión negativa y posterior evaluación de la reconstrucción del tránsito intestinal, es muy alentador. Permitiendo una disminución de la morbimortalidad como así también del número de ostomías. (AU)

Introduction: Patients presenting with diverticular peritonitis (Hinchey III or IV stages) in a context of severe sepsis with hemodynamic instability (septic shock), performing primary anastomosis has a high rate of dehiscence anastomotic and operative mortality, advising the realization of a resection and ostoma in the manner of Hartmann. However, the high rate of complications related to performing of ostoma, the complexity of intestinal transit restoration surgery, associated with the 40% to 60% of Hartmann reversal not performed, has encouraged other variables to be attempted resolution for this complex and serious pathology. Several publications in recent years have proposed the tactic of "damage control surgery" in order to reduce the morbidity of these serious septic charts while reducing the rate of ostomies. The objective of this study is to present our initial experience with this modality of management of the diverticular peritonitis Hinchey III/IV severe sepsis and hemodynamic instability (septic shock) and to carry out a bibliographic review of the subject. Material and method: Observational, descriptive study of case series. Between November 2015 and December 2016. Coloproctology service of the Churruca-Visca hospital medical complex in the city of Buenos Aires and private practice of the authors. The technique of abbreviated laparotomy and temporary closure of the abdomen was used by a negative pressure system. Results: In the period described, 17 patients with generalized purulent or fecal peritonitis of diverticular origin were operated. Fourteen cases were Hinchey III (82.36%) and 3 cases Hinchey IV (17.64%).In 3 cases, hemodynamic instability was observed in the preoperative or intraoperative period. all of them corresponding to Hinchey's Stage IV. The 3 cases treated using this surgical tactic are described. Discussion: The high morbidity rate of this subgroup of patients encouraged various surgical groups to implement the damage control technique, thus allowing patients to stabilize hemodynamically and in a second time evaluate reconstruction intestinal transit. In line with these publications, two of our patients operated on with this strategy could be anastomosated after the second abdominal wash. Conclusion: In patients with severe diverticular peritonitis associated with septic shock, the concept of abbreviated laparotomy with initial control of the septic focus, temporary closure of the abdomen with negative pressure system and subsequent evaluation of transit reconstruction intestinal, it's encouraging. Allowing a decrease in morbidity as well as the number of ostomies. (AU)

Humans , Male , Female , Middle Aged , Aged , Peritonitis/surgery , Shock, Septic , Diverticulitis, Colonic/surgery , Negative-Pressure Wound Therapy , Laparotomy/methods , Peritonitis/etiology , Reoperation , Peritoneal Lavage , Colostomy/methods , Colostomy/mortality , Acute Disease , Epidemiology, Descriptive , Sepsis , Diverticulitis, Colonic/complications , Abdominal Wound Closure Techniques , Laparotomy/mortality
Coluna/Columna ; 18(3): 246-250, July-Sept. 2019. graf
Article in English | LILACS | ID: biblio-1019781


ABSTRACT Objective To describe the indications and contraindications of negative pressure assisted wound therapy as well as a modification to the negative pressure technique that has been shown to shorten the number of changes of dressings and hospital stay with the early closure of the wound. Methods A review of the existing literature in the databases OVID, PubMed, Cochrane and Medigraphic was carried out in relation to the pressure-assisted closure of wounds. This is a non-invasive and active healing system that uses localized and controlled negative pressure, which consists of a specialized dressing that includes reticulated foam that removes the exudates through a tube to an airtight container. This set forms microdeformations in the wound bed, which are known to cause an important increase in fibroblastic migration and consequently of higher quality tissue, granulation tissue formation and angiogenesis. Results It was found that this method shortens the number of days of hospital stay. The technique describes the primary closure of the wound after intense cleansing and debridement of the non-viable tissue and signs of infection. Conclusions Negative pressure wound therapy is effective for the treatment of deep infections in postsurgical spinal wound, with average time of use of 1 to 4 weeks in the most severe cases. Level of evidence IV; Case Series.

RESUMO Objetivo Descrever as indicações e contraindicações da terapia de cicatrização assistida pela pressão negativa, assim como uma modificação nessa técnica, que demonstrou diminuir o número de recargas de curativos e de internação hospitalar, por meio da manipulação do fechamento precoce de feridas. Métodos Foi realizada uma revisão da literatura, em bases de dados da OVID, PubMed, Cochrane e Medigraphic, sobre a terapia de cicatrização assistida pela pressão negativa. Este é um sistema ativo de cura não invasivo utilizando pressão negativa controlada e localizada, que consiste em um curativo especializado, com a inclusão de uma espuma reticulada que conduz, através de um tubo de exsudado, a um recipiente hermético, formando micro deformações no leito da ferida. A técnica tem provado ser uma importante causa do aumento da migração fibroblástica e, consequentemente, de tecido de qualidade mais elevada, junto com a formação de tecido de granulação e angiogénese. Resultados Em relação à técnica, descreve-se as etapas como forma de fechamento primário da ferida após limpeza intensa, desbridamento da área não viável e das características infecciosas. Além disso, o uso da técnica demonstrou diminuir o número de dias de internação hospitalar. Conclusão Este método de pressão negativa é eficaz para o tratamento de infecções pós-cirúrgicas profundas da coluna vertebral, sendo usado, em média, de um a quatro semanas nos casos mais graves. Nível de evidência IV; Série de Casos.

RESUMEN Objetivo Describir las indicaciones y contraindicaciones de la terapia de cicatrización de heridas asistida por presión negativa, así como una modificación a la técnica de presión negativa que ha demostrado acortar el número de recambio de apósitos y la estancia hospitalaria con el cierre temprano de la herida. Métodos Se realizó una revisión de la literatura existente en las bases de datos OVID, PubMed, Cochrane y Medigraphic en relación a la terapia de cicatrización de heridas asistida por presión negativa. Es un sistema de cicatrización no invasivo y activo que utiliza presión negativa localizada y controlada, que consiste de un apósito especializado que incluye esponja reticulada que elimina los exudados a través de un tubo a un recipiente hermético. Este conjunto forma micro deformaciones en el lecho de la herida, que se sabe que causan aumento importante de la migración fibroblástica y, por consiguiente, tejido de mayor calidad, formación de tejido de granulación y angiogénesis. Resultados Se constató que este método acorta el número de días de estancia hospitalaria. La técnica describe el cierre primario de la herida después de limpieza intensa y desbridamiento del tejido no viable y de los signos de infección. Conclusiones La terapia de heridas por presión negativa es eficaz para el tratamiento de las infecciones profundas de heridas en el postoperatorio de la columna vertebral, con un tiempo promedio de uso de 1 a 4 semanas en los casos más severos. Nivel de evidencia IV, Serie de Casos.

Humans , Spine , Negative-Pressure Wound Therapy , Infections
Rev. argent. cir. plást ; 25(1): 21-27, 20190000. fig
Article in Spanish | LILACS, BINACIS | ID: biblio-1358040


Introducción. Los defectos grandes y complejos de piel cabelluda en los pacientes pediátricos representan un reto para el cirujano plástico que se enfrenta a este tipo de lesiones, debido a la dificultad de las técnicas quirúrgicas disponibles en este grupo de edad. El objetivo primario en el manejo de este tipo de heridas es lograr una cobertura adecuada de la bóveda craneana, con el propósito fundamental de prevenir la exposición y desecación ósea y la sepsis. El objetivo secundario será el resultado estético, en el cual se buscará atenuar la alopecia y esconder las cicatrices. Objetivo. El objetivo de este trabajo es dar a conocer el manejo quirúrgico para la reconstrucción de heridas complejas de cuero cabelludo en forma secuencial con buenos resultados estéticos. Material y métodos. Se presenta el caso de masculino de 1 año quien fue víctima de mordedura de perro, presentando herida de espesor total en piel cabelluda en región parietooccipital, con pérdida de cobertura cutánea, reconstrucción primaria con injerto de espesor parcial y en segundo tiempo quirúrgico el uso de expansores tisulares con fines estéticos. Resultados. Posterior a 8 meses con un total de 4 tiempos quirúrgicos (1- lavado quirúrgico, remodelación de bordes, avance de colgajos locales,toma y aplicación de injerto de espesor parcial con fijación por medio de sistema de presión negativa, 2- retiro de sistema de presión negativa, 3- colocación de expansores, 4- retiro de expansores, avance de colgajo occipital y cierre primario) se obtiene un resultado estético favorable. Conclusiones. El manejo de heridas complejas en piel cabelluda en población pediátrica con injertos de espesor parcial ha demostrado eficacia al lograr una cobertura inmediata del defecto con menor morbilidad que otras técnicas, aún más cuando se apoyan de herramientas como el sistema de presión negativa. La reconstrucción posterior con expansores tisulares es aconsejable para lograr la disminución de secuelas.

Introduction. Large and complex scalp defects in pediatric patients represent a challenge for the plastic surgeon who faces this kind of injuries, due to the difficulty of the surgical techniques available in this age group. The primary goal in the management of this kind of wounds is to achieve adequate coverage of the cranial vault, with the main purpose of preventing bone exposure and sepsis. The secondary goal is to reach an aesthetic result, where alopecia can be attenuated, and the scars hidden. Objective. The objective of this work is to present the sequential surgical management for the reconstruction of complex scalp wounds with adequate aesthetic results. Material and methods. We present the case of a 1-year-old child who was bitten by a dog, presenting a full-thickness wound on the scalp in the parieto-occipital region, with skin coverage loss, primary reconstruction with a partial-thickness graft, and in the second surgical procedure, the use of tissue expanders for aesthetic purposes. Results: After 8 months with a total of 4 surgical procedures (1- antisepsis, edges remodeling, local flaps advance, harvesting and application of partial thickness skin graft with negative pressure system, 2- removal of negative pressure system, 3- placement of tissue expanders, 4- removal of tissue expanders, occipital flap advance and primary closure) a favorable aesthetic result is obtained. Conclusions. The management of scalp complex wounds in the pediatric population with partial thickness skin grafts has demonstrated efficacy by achieving immediate coverage of the defect with lower morbidity than other techniques, even more when using tools such as the negative pressure system, subsequent reconstruction with tissue expanders is an option in order to achieve sequelae reduction

Humans , Male , Infant , Scalp/injuries , Transplantation/methods , Wounds and Injuries/therapy , Bites and Stings/therapy , Tissue Expansion Devices , Reconstructive Surgical Procedures/methods , Negative-Pressure Wound Therapy/methods
Article in English | AIM, AIM | ID: biblio-1272754


Background: Surgical site infections are major complications of coronary artery bypass grafting using bilateral internal thoracic arteries. In this study we reviewed the results of using INPWT for high risk patients with coronary artery bypass grafting (CABG) using bilateral internal mammary arteries. Patients and methods: From January 2013 to December 2016, patients with coronary artery bypass grafting using bilateral mammary arteries were enrolled in this study. Patients were from Kasr El-Einy, Beni-Suef and Fayoum University Hospitals. The total number was 427 patients, where INPWT was used in 161 patient, and conventional sterilized dressing was done in 266 patients. 2 groups were matched for statistical analysis, the first group was the control and the second group was where INPWT was used. Results: The results related to sternal wound infections were similarly attributed to the conventional group (10.9%) and the INPWT group (10.2%) (P=1.00). Patients treated with INPWT had less rate of infection than those with conventional dressing (5.5% versus 10.2%, P= 0.210), this difference was not statistically significant. Interaction tests also showed comparable results for SSI (surgical site infections) among patients with or without significant co-morbidities. Conclusion: This study suggests that the use of INPWT did not decrease the incidence of sternal wound infections in patients who had CABG surgery using bilateral internal mammary harvesting (BIMA). A larger randomized study is needed to evaluate the efficacy of this technique

Coronary Artery Bypass , Egypt , Negative-Pressure Wound Therapy , Surgical Wound Infection
Niger. j. surg. (Online) ; 25(1): 14-20, 2019. ilus
Article in English | AIM, AIM | ID: biblio-1267524


Background: Vacuum-assisted closure (VAC) therapy has been shown to be beneficial in a variety of wounds. However, evidence of its benefit in diabetic foot ulcers (DFUs), especially with respect to Indian population, is sparse. Methodology: This randomized controlled trial included DFUs of Wagner's Grades 1 and 2. Patients were further stratified with respect to DFU size <10 cm and ≥10 cm. Patients with vascular disease, osteomyelitis, and bilateral DFUs were excluded from the study. The enrolled patients were randomized to receive VAC therapy or conventional dressing. The time to wound healing, granulation tissue formation, and complications such as pain, infection, and bleeding were compared between the two groups. Results: A total of sixty patients were randomized, of which 27 in each group were analyzed. The mean time to healing in days was significantly less in VAC group (22.52 vs. 3.85; P < 0.0001). Mean time to achieve 75%­100% granulation tissue cover was significantly less in VAC group (23.33 vs. 32.15; P < 0.0001). Rate of granulation tissue formation was also found to be significantly better in VAC group (2.91 cm2/day vs. 2.16 cm2/day; P = 0.0306). There was no difference between the two groups with respect to wound infection and bleeding which are commonly attributed to VAC therapy. VAC therapy group had significantly lesser pain at week 3 (Visual Analog Scale score 3 vs. 4; P = 0.004). Conclusion: VAC therapy significantly decreases the time to complete wound healing, hastens granulation tissue formation, and reduces the ulcer area compared to conventional dressing. The study did not find any significant increase in the bleeding and infection in the VAC therapy group

Granulation Tissue , India , Negative-Pressure Wound Therapy , Wound Healing
Clinics ; 74: e937, 2019. tab, graf
Article in English | LILACS | ID: biblio-1011913


OBJECTIVE: Despite advances in diffuse peritonitis treatment protocols, some cases develop unfavorably. With the advent of vacuum therapy, the use of laparostomy to treat peritonitis has gained traction. Another treatment modality is continuous peritoneal lavage. However, maintaining this technique is difficult and has been associated with controversial results. We propose a new model of continuous peritoneal lavage that takes advantage of the features and benefits of vacuum laparostomy. METHOD: Pigs (Landrace and Large White) under general anesthesia were submitted to laparostomy through which a multiperforated tube was placed along each flank and exteriorized in the left and lower right quadrants. A vacuum dressing was applied, and intermittent negative pressure was maintained. Peritoneal dialysis solution (PDS) was then infused through the tubes for 36 hours. The stability of peritoneostomy with intermittent infusion of fluids, the system resistance to obstruction and leakage, water balance, hemodynamic and biochemical parameters were evaluated. Fluid disposition in the abdominal cavity was analyzed through CT. RESULTS: Even when negative pressure was not applied, the dressing maintained the integrity of the system, and there were no leaks or blockage of the catheters during the procedure. The aspirated volume by vacuum laparostomy was similar to the infused volume (9073.5±1496.35 mL versus 10165±235.73 mL, p=0.25), and there were no major changes in hemodynamic or biochemical analysis. According to CT images, 60 ml/kg PDS was sufficient to occupy all intra-abdominal spaces. CONCLUSION: Continuous peritoneal lavage with negative pressure proved to be technically possible and may be an option in the treatment of diffuse peritonitis.

Animals , Peritoneum/surgery , Peritoneal Lavage/methods , Negative-Pressure Wound Therapy/methods , Laparotomy/methods , Peritoneum/diagnostic imaging , Swine , Vacuum , Tomography, X-Ray Computed , Models, Animal
Acta cir. bras ; 34(9): e201900907, 2019. graf
Article in English | LILACS | ID: biblio-1054696


Abstract Purpose: To describe a case report of FG associated with NPWT in the treatment of complex wound on the distal third of the lower limb with bone exposure. Case Report: A 59-year-old patient with chronic left tibial osteomyelitis since childhood underwent extensive debridement of the distal tibial diaphysis (40% of bone thickness per 10 cm extension) and placement of bioactive glass S53P4. Distal necrosis occurred in the fasciocutaneous flap used as the primary bone coverage. After flap debridement, the case was resolved with FG, directly on the exposed bone and biomaterial, associated with NPWT. Three weeks after the first FG session over bony tissue, 100% granulation was achieved with NPWT. The closure was completed with thin laminated skin graft over the granulated wound area. Discussion: The association of FG and NPWT is not known in the clinical practice. Except for the only one experimental study described by Kao et al.4, the theme was not addressed in the medical literature before. In this clinical case, the result obtained regarding the granulation tissue formation drew attention and prevented the use of more complex flaps such as the microsurgical ones. Accelerated granulation tissue formation was observed, filling an extensive and deep bone defect, even with infected bone and biomaterial. Low morbidity and no complications were observed with the use of FG associated with NPWT. When the grafted fat was compacted with the NPWT, it seemed to behave as a true autologous biological matrix with large amount of cells. To date, scientific studies on fat grafting have focused on the cellular aspect (adipocytes and mesenchymal cells), growth factors and fat differentiation in different tissues. The property of aspirated adipose tissue as a biological matrix seemed to be revealed by the application of NPWT in association with FG. This new roll for the aspirated fat tissue may represent a new research field in plastic surgery.

Humans , Male , Middle Aged , Osteomyelitis/surgery , Wound Healing , Adipose Tissue/transplantation , Negative-Pressure Wound Therapy/methods , Surgical Flaps , Glass
Article in English | WPRIM | ID: wpr-762859


Congenital absent sternum is a rare birth defect that requires early intervention for optimal long-term outcomes. Descriptions of the repair of absent sternum are limited to case reports, and no preferred method for management has been described. Herein, we describe the use of porcine acellular dermal matrix to reconstruct the sternum of an infant with sternal infection following attempted repair using synthetic mesh. The patient was a full-term male with trisomy 21, agenesis of corpus callosum, ventricular septal defect, patent ductus arteriosus, right-sided aortic arch, and congenital absence of sternum with no sternal bars. Following removal of the infected synthetic mesh, negative pressure wound therapy with instillation was used to manage the open wound and provide direct antibiotic therapy. When blood C-reactive protein levels declined to ≤2 mg/L, the sternum was reconstructed using porcine acellular dermal matrix. At 21 months postoperative, the patient demonstrated no respiratory issues. Physical examination and computed tomography imaging identified good approximation of the clavicular heads and sternal cleft and forward curvature of the ribs. This case illustrates the benefits of negative pressure wound therapy and acellular dermal matrix for the reconstruction of absent sternum in the context of infected sternal surgical site previously repaired with synthetic mesh.

Acellular Dermis , Agenesis of Corpus Callosum , Aorta, Thoracic , C-Reactive Protein , Congenital Abnormalities , Down Syndrome , Ductus Arteriosus, Patent , Early Intervention, Educational , Head , Heart Septal Defects, Ventricular , Humans , Infant , Male , Methods , Negative-Pressure Wound Therapy , Physical Examination , Ribs , Sternum , Surgical Mesh , Thoracic Surgery , Wounds and Injuries
Article in Korean | WPRIM | ID: wpr-760158


BACKGROUND AND OBJECTIVES: This study compared two types of skin graft reconstruction for the defect of the radial forearm free flap. SUBJECTS AND METHOD: Ten cases of split-thickness skin graft (STSG) harvested from the thigh were analyzed. Also, ten cases of full-thickness skin graft (FTSG) harvest from the inguinal area applied with vacuum-assisted closure (VAC) system were analyzed. RESULTS: The defect size of the radial forearm was increased more in the STSG group than in the FTSG group (p<0.05). Skin grafts were recovered completely sooner in the FTSG group than in the STSG group although it was not statistically significant (p=0.082). Five complications (pruritus, hypertrophic scar) were found in the donor site in the STSG group (p<0.05). FTSG gave better scores according to the Vancouver Scar Scale in terms of pigmentation, pliability, and height (p<0.05). CONCLUSION: FTSG harvested from the inguinal area with the application of VAC system has many advantages for the defect of the radial forearm free flap although it is usually used for smaller size defects than for STSGs.

Cicatrix , Forearm , Free Tissue Flaps , Humans , Methods , Negative-Pressure Wound Therapy , Pigmentation , Pliability , Reconstructive Surgical Procedures , Skin Transplantation , Skin , Thigh , Tissue Donors , Transplants