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2.
Article in Korean | WPRIM | ID: wpr-759636

ABSTRACT

OBJECTIVES: This study examined the relationship between the presence of allergic rhinitis and the nutritional intake levels of Korean infants. METHODS: The study involved a total of 1,214 infant subjects aged 1~5 months from the 2013~2016 KNHNES (Korea National Health and Nutrition Examination Survey). The Subjects were classified into two groups based on the presence of allergic rhinitis: Non-allergic rhinitis infants (NARI, n=1,088) and allergic rhinitis infants (ARI, n=126). The general characteristics and family history of allergies, nutrient intake status, nutrient supplement intake, and breast milk and baby food start period data of the two groups were compared. All statistical analyses accounted for the complex sampling design effect and sampling weights. RESULTS: The mean age was 0.5 years old in the ARI group compared to the NARI group. In the residence, the rate of urban was higher in ARI. The family history revealed a significant difference between the two groups, particularly those of mothers rather than fathers. The nutrient intake levels were high in energy, phosphorus, sodium, potassium, iron, riboflavin, niacin, and polyunsaturated fatty acids. Breastfeeding was significantly higher in the ARI group than in the NARI group. The baby food start period was 0.3 months earlier in NARI group than in ARI group. The height, body weight, and birth weight were higher in ARI group than NARI group. The result of Odds ratio analysis showed that excess energy, protein, calcium, phosphorus, iron, riboflavin, and niacin intake increases the risk of allergic rhinitis. CONCLUSIONS: These results can be used as data to develop nutrition guidelines for allergic rhinitis infants.


Subject(s)
Birth Weight , Body Height , Breast Feeding , Calcium , Fathers , Fatty Acids, Unsaturated , Humans , Hypersensitivity , Infant , Iron , Korea , Milk, Human , Mothers , Niacin , Nutrition Policy , Nutrition Surveys , Odds Ratio , Phosphorus , Potassium , Rhinitis , Rhinitis, Allergic , Riboflavin , Sodium , Weights and Measures
3.
Article in English | WPRIM | ID: wpr-765651

ABSTRACT

OBJECTIVE: To examine the effect of niacin on the progression of carotid intima-media thickness (IMT) in patients with high level of lipoprotein (Lp) (a). METHODS: Patients at low-density lipoprotein-cholesterol goal but with Lp (a) >25 mg/dL and mean carotid IMT >0.75 mm were included. Eligible patients were randomized at a 1:2 ratio into one of two groups for 24 months: control or 1,500 mg extended release niacin. The primary study outcomes were the percentage changes in mean and maximal carotid IMT. The percentage change in lipid profiles including Lp (a) was analyzed as a secondary study outcome. RESULTS: Among 96 randomized patients, 31 completed the study (mean age: 65 years; male: 44%). At follow-up, the percentage change in mean carotid IMT was not significantly different between the two groups (−1.4%±15.5% and −1.1%±7.3% in the control and niacin groups, respectively, p=0.95). The percentage change in maximal carotid IMT was also similar in the two groups (0.7%±16.5% and −4.4%±11.6%, respectively, p=0.35). Elevation of high-density lipoprotein-cholesterol tended to be higher in the niacin group (p=0.07), and there was a significant difference in the percentage change in hemoglobin A1c between the two groups (−1.9%±2.2% and 3.3%±6.7%, respectively, p=0.02). Reduction of Lp (a) was greater in the niacin-treated group compared to placebo, but the difference was not statistically significant. CONCLUSION: Treatment with niacin for two years did not inhibit the progression of carotid intima-media thickening in patients with high Lp (a) level. However, this study may have been underpowered to evaluate the primary study outcome.


Subject(s)
Arteries , Carotid Artery Diseases , Carotid Intima-Media Thickness , Drug Therapy , Follow-Up Studies , Humans , Lipoprotein(a) , Lipoproteins , Male , Niacin
4.
Journal of Bone Metabolism ; : 151-160, 2019.
Article in English | WPRIM | ID: wpr-764255

ABSTRACT

BACKGROUND: The correlations between the amount of daily fiber intake and bone mineral densities (BMDs) in Korean adult population were investigated in our study. METHODS: Utilizing the Korean National Health and Nutrition Examination Survey in 2011, multivariable linear regression was performed to explore the association between fiber consumption and BMD of lumbar vertebrae 1 to 4 (L1–4 total), L1, L2, L3, and L4 vertebrae, femur neck, femur total, and trochanter. All models were adjusted for age, body mass index, vitamin D level, smoking, physical activity, alcohol use, contraceptive use, hormonal replacement therapy, consumption of carbohydrate, protein, fat, calcium, phosphate, iron, thiamine, riboflavin, niacin, and vitamin C. RESULTS: In males aged between 18 and 45, fiber intake significantly increased BMDs of L1 (coefficient β=0.004, P=0.040) and L2 (β=0.004, P=0.038) while daily protein consumption significantly lowered BMDs of femur neck (β=−0.001, P=0.009), femur total (β=−0.001, P=0.008), and trochanter (β=−0.001, P=0.008). In males aged 65 and older, nutrient intake shows no significant correlations with BMDs except fat consumption was inversely associated with BMD of trochanter (β=−0.001, P=0.017). In females aged between 18 and 45, fiber intake shows no significant relationship with BMDs while daily fat consumption significantly increased BMDs of L1 (β=0.001, P=0.028), L2 (β=0.001, P=0.024), L3 (β=0.001, P=0.033), and L1–4 total (β=0.001, P=0.017). CONCLUSIONS: Fiber intake was a protective factor of lumbar spine (L1 and L2) BMD in male aged between 18 and 45 but not in female participants of any age groups.


Subject(s)
Adult , Ascorbic Acid , Body Mass Index , Bone Density , Calcium , Dietary Fiber , Female , Femur , Femur Neck , Humans , Iron , Linear Models , Lumbar Vertebrae , Male , Motor Activity , Niacin , Nutrition Surveys , Osteoporosis , Protective Factors , Riboflavin , Smoke , Smoking , Spine , Thiamine , Vitamin D
5.
Article in English | WPRIM | ID: wpr-760635

ABSTRACT

BACKGROUND/OBJECTIVES: The leaves of Moringa oleifera (MO) and Moringa stenopetala (MS) commonly grown in Ethiopia possess potential nutritional and medicinal value. The aim of this study was to evaluate the nutritional and functional characteristics of the dried leaf powder from two Moringa species to develop sustainable nutritional supplements for Ethiopians from locally grown plant sources. SUBJECTS/METHODS: Freshly harvested and air-dried MO and MS leaves were authenticated and the nutritional contents, such as protein, ash, lipids, and selected vitamins and minerals, were analyzed using standard analytical procedures. Amino acid compositions were also determined by an amino acid analyzer. Nine-week-old mice were randomly divided into four groups to investigate the anti-obesity effects of Moringa. The first group was fed a basal diet, the second group a high-fat diet, and the others were fed a high-fat diet containing 0.1% Moringa leaf powder from each species. After seven weeks, serum indices related to lipid profiles from each mouse were analyzed. RESULTS: The present study revealed high protein (28–29%) and ash (7–11%) contents. Glutamic acid, aspartic acid, proline, and leucine were the most abundantly found amino acids in both species. The predominant minerals in the leaf powder were calcium (826–1,530 mg/100 g), potassium (794–904 mg/100 g), and magnesium (286-431 mg/100 g). Pyridoxine (475.06 mg/100 g) and vitamin E (34.2 mg/100 g) were found only in MS. Niacin was found only in MO at 32.21 mg/100 g, whereas ascorbic acid was found in both species (3.89 and 6.19 mg/100 g dry weight for MO and MS, respectively). The results of the animal study showed that mice on a high-fat diet containing 0.1% MO leaf powder alleviated the elevation of cholesterol, triglycerides, and low-density lipoprotein cholesterol induced by the high fat diet. MO was more effective than MS in preventing hypercholesterolemia and fat deposition. CONCLUSIONS: The findings in this work confirmed that Moringa leaves of both MO and MS possessed high nutritional value but MO was better at preventing the harmful effects of the high-fat diet than MS.


Subject(s)
Amino Acids , Animals , Ascorbic Acid , Aspartic Acid , Calcium , Cholesterol , Diet , Diet, High-Fat , Ethiopia , Glutamic Acid , Hypercholesterolemia , Leucine , Lipoproteins , Magnesium , Mass Screening , Mice , Minerals , Miners , Moringa oleifera , Moringa , Niacin , Nutritive Value , Plants , Potassium , Proline , Pyridoxine , Triglycerides , Vitamin E , Vitamins
6.
Article in English | WPRIM | ID: wpr-760633

ABSTRACT

BACKGROUND/OBJECTIVES: The elderly are reported to have a high prevalence of nutritional anemia when they have lower intakes of nutrients or chronic diseases. This study was conducted to compare nutritional status according to nutritional anemia and to determine associations between nutritional anemia and chronic diseases in Korean elderly. MATERIALS/METHODS: This study utilized data on 3,258 elderly aged ≥ 65 years gathered during the 6(th) Korea National Health and Nutrition Examination Survey 2013–2015. Subjects were divided into nutritional anemia (NA) group (n = 415) and non-NA group (n = 2,843) by hemoglobin concentration. Nutrient intakes were assessed using dietary intake data obtained using the 24-hour recall method. The odds ratios (ORs) for nutritional anemia by chronic diseases were determined. Statistical analysis was performed using SPSS Ver. 23.0. RESULTS: Of 3,258 subjects, 12.7% had nutritional anemia. Intakes of potatoes, pulses, and mushrooms by males and potatoes, fruits, meats, eggs, and seafood by females were significantly lower in NA group than in non-NA group. The proportion of the subjects whose intakes of protein, vitamin A, vitamin B₁, vitamin B₂, niacin, and iron less than estimated average requirement (EAR) were significantly higher in NA group compared to non-NA group. After adjusting for age, the number of family members, energy intake, and alcohol drinking, ORs for nutritional anemia in the subjects with diabetes and myocardial infarction or angina pectoris were significantly higher by 1.74 times and 1.59 times as compared to the subjects without those diseases, respectively. However, ORs for nutritional anemia in the subjects with obesity, abdominal obesity, and hypertriglyceridemia were significantly lower by 0.64 times, 0.60 times, and 0.59 times as compared to the subjects without those diseases, respectively. CONCLUSIONS: The results of this study suggested that nutritional management should be done to enable the Korean elderly to consume foods with high hematopoietic nutrients density to prevent nutritional anemia. Korean elderly need to make regular efforts to check for nutritional anemia.


Subject(s)
Agaricales , Aged , Alcohol Drinking , Anemia , Angina Pectoris , Chronic Disease , Eggs , Energy Intake , Female , Fruit , Humans , Hypertriglyceridemia , Iron , Korea , Male , Meat , Methods , Myocardial Infarction , Niacin , Nutrition Surveys , Nutritional Status , Obesity , Obesity, Abdominal , Odds Ratio , Ovum , Prevalence , Seafood , Solanum tuberosum , Vitamin A , Vitamins
7.
Article in English | WPRIM | ID: wpr-760615

ABSTRACT

BACKGROUND/OBJECTIVES: The aim of this study was to analyze specific foods influencing absolute nutrient intake and between-person variations of nutrient intake among Korean preschoolers. SUBJECTS/METHODS: This study included 2,766 participants aged 1–5 years in the 2009–2013 Korea National Health and Nutrition Examination Surveys. Dietary data were obtained from a 24-h dietary recall method. Major food sources of absolute nutrient intake were evaluated based on percent contribution of each food. To assess the contribution of specific foods to between-person variations in nutrient intake, stepwise multiple regressions were performed and cumulative R2 was used. RESULTS: White rice and milk were main food sources of energy, protein, carbohydrate, phosphorus, iron, potassium, thiamin, riboflavin, and niacin. The percentage of fat contributed by milk was 21.3% which was the highest, followed by pork, soybean oil, and egg. White rice accounted for 25% and 40% of total variability in total energy and carbohydrate intakes, respectively. About 39% of variation in calcium intake was explained by milk while 40% of variation in phosphorous intake was explained by cheese. The top 10 foods contributing to between-person variations in nutrient intakes were similar with food items that mainly contributed to absolute nutrient intakes. The number of foods explaining 90% of absolute amounts of nutrient intakes varied from 28 for vitamin A to 80 for iron. CONCLUSIONS: This study identified specific foods that contributed to absolute nutrient intakes and between-person variations in nutrient intakes among Korean preschoolers. Our findings can be used to develop dietary assessment tools and establish food-based dietary guidelines for young children.


Subject(s)
Calcium , Cheese , Child , Diet , Humans , Iron , Korea , Methods , Milk , Niacin , Nutrition Assessment , Nutrition Policy , Nutritional Status , Ovum , Phosphorus , Potassium , Red Meat , Riboflavin , Soybean Oil , Vitamin A
8.
Article in English | WPRIM | ID: wpr-741700

ABSTRACT

BACKGROUND/OBJECTIVES: The NAD+ precursor nicotinamide riboside (NR) is a type of vitamin B3 found in cow's milk and yeast-containing food products such as beer. Recent studies suggested that NR prevents hearing loss, high-fat diet-induced obesity, Alzheimer's disease, and mitochondrial myopathy. The objective of this study was to investigate the effects of NR on inflammation and mitochondrial biogenesis in AML12 mouse hepatocytes. MATERIALS/METHODS: A subset of hepatocytes was treated with palmitic acid (PA; 250 µM) for 48 h to induce hepatocyte steatosis. The hepatocytes were treated with NR (10 µM and 10 mM) for 24 h with and without PA. The cell viability and the levels of sirtuins, inflammatory markers, and mitochondrial markers were analyzed. RESULTS: Cytotoxicity of NR was examined by PrestoBlue assay. Exposure to NR had no effect on cell viability or morphology. Gene expression of sirtuin 1 (Sirt1) and Sirt3 was significantly upregulated by NR in PA-treated hepatocytes. However, Sirt1 activities were increased in hepatocytes treated with low-dose NR. Hepatic pro-inflammatory markers including tumor necrosis factor-alpha and interleukin-6 were decreased in NR-treated cells. NR upregulated anti-inflammatory molecule adiponectin, and, tended to down-regulate hepatokine fetuin-A in PA-treated hepatocytes, suggesting its inverse regulation on these cytokines. NR increased levels of mitochondrial markers including peroxisome proliferator-activated receptor γ coactivator-1α, carnitine palmitoyltransferase 1, uncoupling protein 2, transcription factor A, mitochondrial and mitochondrial DNA in PA-treated hepatocytes. CONCLUSIONS: These data demonstrated that NR attenuated hepatic inflammation and increased levels of mitochondrial markers in hepatocytes.


Subject(s)
Adiponectin , alpha-2-HS-Glycoprotein , Alzheimer Disease , Animals , Beer , Carnitine O-Palmitoyltransferase , Cell Survival , Cytokines , DNA, Mitochondrial , Fatty Liver , Gene Expression , Hearing Loss , Hepatocytes , Inflammation , Interleukin-6 , Mice , Milk , Mitochondria , Mitochondrial Myopathies , Niacin , Niacinamide , Obesity , Organelle Biogenesis , Palmitic Acid , Peroxisomes , Sirtuin 1 , Sirtuins , Transcription Factors , Tumor Necrosis Factor-alpha
9.
Article in Korean | WPRIM | ID: wpr-740549

ABSTRACT

PURPOSE: This study examined the food and nutrient intake of Korean elderly according to the anxiety and depressive condition using the data from the Korea National Health and Nutrition Survey (KNHANES) from 2013 to 2015. METHODS: The participants were 3,504 elderly people over 65 years of age (1,523 in men and, 1,981 in women). The dietary information was analyzed using the 24-hour recall data. The anxiety and depressive state was assessed using the self-reported scale EQ-5D in the quality of life dimension. The subjects were divided into the anxiety · depression group (AD) and non-anxiety · depression group (NAD) according to their anxiety and depressive conditions. RESULTS: In the male elderly, the AD group had a significantly lower education and economic level and higher proportion in living alone than the NAD group. The percentage of eating lunch and dinner alone in the male AD group was higher than that of the NAD group. The female AD group showed less a lower frequency of dinner than the NAD group. The male AD group had a lower consumption of total foods, fish and shellfishes, seaweeds, mushrooms, oils and fats, and seasonings than the NAD group. With regard to the nutrient intake, the male elderly NAD group had more sufficient nutrient intakes than the AD group. In particular, the daily intakes of dietary fiber, riboflavin, niacin, potassium and iron were significantly lower in the AD group. To compare with the nutrient density of the two groups, the vitamin C and niacin intakes were lower in the AD group than in the NAD group. Overall, the nutritional status of the male AD group was significantly lower than that of the NAD group. Meanwhile, the female elderly had showed a smaller difference in nutrient intake according to their anxiety and depressive condition. CONCLUSION: These results of this study show that more nutritional education and emotional support are needed to improve the nutritional status and health of the male elderly with anxiety or depression.


Subject(s)
Agaricales , Aged , Anxiety , Ascorbic Acid , Depression , Dietary Fiber , Eating , Education , Fats , Female , Humans , Iron , Korea , Lunch , Male , Meals , NAD , Niacin , Nutrition Surveys , Nutritional Status , Oils , Potassium , Quality of Life , Riboflavin , Seasons , Shellfish
10.
Article in Korean | WPRIM | ID: wpr-740546

ABSTRACT

PURPOSE: This study examined dietary and health characteristics of the young-old and the old-old by food security status. METHODS: The study used data from the 6th (2013 ~ 2015) Korea National Health and Nutrition Examination Survey. The study subjects consisted of 3,948 subjects, of whom 2,445 were the young-old (aged 65 to 74 years) and 1,503 were the old-old (aged 75 years and over). Food security status was evaluated using an 18-item questionnaire. Energy intake, nutrient densities, and prevalence of insufficient nutrient intake were assessed. Food intake was evaluated in terms of the number of food group servings. Dietary behaviors and health status were also assessed. RESULTS: The prevalence of food insecurity among the young-old and the old-old was 10.0% and 11.6%, respectively. Among the young-old, the food insecure group had a significantly higher level of prevalence of insufficient intake for all the nutrients (protein, vitamin A, thiamin, riboflavin, niacin, vitamin C, calcium, phosphorous, and iron) assessed in this study compared with the food secure group. In case of the old-old, significant differences were found only for four nutrients (protein, riboflavin, niacin, and phosphorus) in the prevalence of insufficient nutrient intake between the food secure and the food insecure groups. Kinds of food groups with significantly different numbers of servings by food security status were dissimilar between the two age groups. In both the age groups, the food insecure group consumed a significantly lower number of servings in meat·fish·eggs·legumes and fruits than the food secure group; grains and vegetables intake in the young-old and oils·sweets intake in the old-old differed in the number of servings by food security status. Among the young-old, the prevalence of chewing difficulties in the food insecure group was significantly higher than that of the food secure group, while among the old-old, no significant differences were found by food security status. CONCLUSION: Dietary and health characteristics of the young-old and the old-old differed by food security status. Such differences were more apparent in the young-old than the old-old. Therefore, it is suggested that food and nutrition assistant programs should be designed with consideration of the differences.


Subject(s)
Ascorbic Acid , Calcium , Diet , Eating , Energy Intake , Food Supply , Fruit , Humans , Korea , Mastication , Niacin , Nutrition Surveys , Prevalence , Riboflavin , Vegetables , Vitamin A
11.
Article in English | WPRIM | ID: wpr-740478

ABSTRACT

BACKGROUND: The health condition of old age is affected by various factors such as economic level, disease condition, and nutrition. With the aging population in Korea, the ratio of single-person households increased rapidly. Research on the health status and nutrition of the elderly in the single-person household is very insufficient. In this study, we compared the health and nutritional status of the elderly by the household type. METHODS: Data from the 2013 to 2014 Korea National Health and Nutrition Examination Survey were used. A total of 2,730 patients were classified into 2 groups (single-person, with family), and general, chronic disease, health behavior, nutrient intake, and food insecurity status were compared by the statistical analysis. RESULTS: Single-person households had a low economic and educational level and a higher percentage of women. In addition, obesity, hypertension, dyslipidemia, stroke, myocardial infarction disease rate was significantly higher. Sing-person households answered that their subjective health status was bad, and their quality of life was low. As a result of analysis of the quality of the diet in the single-person, the intake of protein, calcium, iron, vitamin B2, niacin, and vitamin C was significantly lower. In particular, the intake of calcium was the most insufficient. Food insecurity has also been observed, including the inability to consume diverse and sufficient foods due to economic difficulties. CONCLUSIONS: More attention should be paid to the health of single-person households in elderly population and various policies should be prepared.


Subject(s)
Aged , Aging , Ascorbic Acid , Calcium , Chronic Disease , Diagnostic Self Evaluation , Diet , Dyslipidemias , Family Characteristics , Female , Food Supply , Health Behavior , Humans , Hypertension , Iron , Korea , Myocardial Infarction , Niacin , Nutrition Surveys , Nutritional Status , Obesity , Quality of Life , Riboflavin , Single Person , Stroke
12.
Braz. j. biol ; 78(4): 686-690, Nov. 2018. graf
Article in English | LILACS | ID: biblio-951609

ABSTRACT

Abstract Kiwifruit are a popular fruit worldwide; however, plant growth is threatened by abiotic stresses such as drought and high temperatures. Niacin treatment in plants has been shown to increase NADPH levels, thus enhancing abiotic stresses tolerance. Here, we evaluate the effect of niacin solution spray treatment on NADPH levels in the kiwifruit cultivars Hayward and Xuxiang. We found that spray treatment with niacin solution promoted NADPH and NADP+ levels and decreased both O2·- production and H2O2 contents in leaves during a short period. In fruit, NADPH contents increased during early development, but decreased later. However, no effect on NADP+ levels has been observed throughout fruit development. In summary, this report suggests that niacin may be used to increase NADPH oxidases, thus increasing stress-tolerance in kiwifruit during encounter of short-term stressful conditions.


Resumo Kiwis são uma fruta popular em todo o mundo; No entanto, o crescimento das plantas é ameaçado por estresses abióticos como a seca e as altas temperaturas. O tratamento com niacina em plantas mostrou aumentar os níveis de NADPH, aumentando assim a tolerância a stress abiótico. Aqui, avaliamos o efeito do tratamento com spray de solução de niacina sobre os níveis de NADPH nos cultivares de kiwis Hayward e Xuxiang. Descobrimos que o tratamento por spray com solução de niacina promoveu níveis de NADPH e NADP + e diminuiu a produção de O2·- e os teores de H2O2 nas folhas durante um curto período. Nos frutos, os teores de NADPH aumentaram durante o desenvolvimento precoce, mas diminuíram mais tarde. No entanto, não se observou qualquer efeito nos níveis de NADP + ao longo do desenvolvimento do fruto. Em resumo, este relatório sugere que a niacina pode ser utilizada para aumentar NADPH oxidases, aumentando assim a tolerância ao estresse em kiwis durante o encontro de condições estressantes de curto prazo.


Subject(s)
NADPH Oxidases/drug effects , Actinidia/drug effects , Fruit/drug effects , Niacin/pharmacology , Oxidation-Reduction , Plant Leaves/drug effects , Plant Leaves/metabolism , Free Radicals/metabolism , Fruit/growth & development , NADP/metabolism
13.
Article in Korean | WPRIM | ID: wpr-718559

ABSTRACT

PURPOSE: This study was performed to evaluate the cereal intake status and explore its relationship with the nutritional status of the Korean adults from 2013 ~ 2016, Korean National Health and Nutrition Examination Survey (KNHANES). METHODS: We analyzed dData from the combined 2013 ~ 2016 Korean National Health and Nutrition Examination Survey were analyzed. The analysis included 12,199 adults aged from 19 to 64 years (male, n = 5,127, female, n = 7,072). In this study, according to cereal intake frequency (From food frequency questionnaire), we classified tThe subjects were classified according into the “non-cereal intake (NCI)” group (male, n = 4,290, female, n = 5,578), and “cereal intake (CI)” group (male, n = 837, female, n = 1,494) according to cereal intake frequency (From food frequency questionnaire). RESULTS: Typically, 79.6% of adults did not consume cereals (male 81.6%, female 77.3%);, 13.4% consumed cereals 1–3 times a month (male 12.2%, female 14.8%) and 7.1% consumed cereals more than once a week (male 6.2%, female 7.9%). In the case of both males and females, the nutrient density (nutrient intake per 1,000 kcal) and Index of Nutritional Quality (INQ) of protein, calcium, phosphorous, potassium, vitamin A, vitamin B1, vitamin B2, niacin, and vitamin C in the Non-Cereal group were significantly lower than those of the CI group (respectively, p < 0.01). CONCLUSION: Our These results reveal highlight the low frequency of cereal intake in Korean adults and the better nutritional status in adults who consume cereals. It is hypothesized that tThe data of the present study would is expected to serve as basic data to improve the nutritional status of Korean adults.


Subject(s)
Adult , Ascorbic Acid , Calcium , Edible Grain , Female , Humans , Male , Niacin , Nutrition Surveys , Nutritional Status , Nutritive Value , Potassium , Riboflavin , Thiamine , Vitamin A
14.
Article in English | WPRIM | ID: wpr-716066

ABSTRACT

The dietary behavior of immigrants starts changing upon their arrival in a new country. We evaluated changes in dietary quality of Vietnamese women immigrants in Korea and compared dietary quality with that of Korean women. Fifty-six Vietnamese women immigrants and 56 age-matched Korean women were recruited. Dietary quality were assessed using index of nutritional quality (INQ) and diet quality index-international (DQI-I). Dietary habits were assessed according to 4 dietary behaviors: a prudent, calorie control, dietary fat control, and sodium or salt control diet. DQI-I scores of Vietnamese immigrants decreased after immigration, especially the moderation score, although the variety score increased. Scores were significantly lower than those of Korean subjects (45.1 vs. 64.5; p < 0.001). Vietnamese women immigrants had significantly poorer nutrient balance and calorie intake control, although their fat and sodium control was better than that of Korean woman (p < 0.001). INQs of protein, niacin, phosphorus, iron, zinc were lower in immigrants who had lived longer in Korea than more recent immigrants (p < 0.05). Lower INQs of protein, fiber, vitamin A, B1, B6, C, folate, and phosphorus were related to higher body fat in Vietnamese immigrants (p < 0.05). In conclusion, dietary quality of Vietnamese immigrants decreased after migration, and dietary intake was inadequate compared with that of Korean women. In addition, diet quality of Vietnamese immigrants decreased with length of residence in Korea. There was a negative correlation between diet quality and body fat percent in Vietnamese women immigrants. Findings from this study may help improve diet quality and prevent obesity in Vietnam women immigrants.


Subject(s)
Adipose Tissue , Asian Continental Ancestry Group , Diet , Dietary Fats , Emigrants and Immigrants , Emigration and Immigration , Female , Folic Acid , Feeding Behavior , Humans , Iron , Korea , Niacin , Nutritive Value , Obesity , Phosphorus , Republic of Korea , Sodium , Vietnam , Vitamin A , Zinc
15.
Article in English | WPRIM | ID: wpr-717062

ABSTRACT

Mitochondria are the powerhouses of the cell as well as the primary site of hematopoiesis, which also occurs in the cytoplasm. Hematopoietic stem cells (HSCs) are characterized by a very high turnover rate, and are thus considered to be relatively free from the age-related insults generated by mitochondria. However, HSCs are also subject to these age-related insults, including the incidence of myeloid proliferative diseases, marrow failure, hematopoietic neoplasms, and deterioration of the adaptive human immune system. Recently, NAD⁺ dietary supplements, known as niacin or vitamin B₃, including tryptophan, nicotinic acid, nicotinamide, and the newly identified NAD⁺ precursor nicotinamide riboside, have been shown to play a role in restoring adult stem cell function through the amelioration of mitochondrial dysfunction. This insight motivated a study that focused on reversing aging-related cellular dysfunction in adult mouse muscle stem cells by supplementing their diet with nicotinamide riboside. The remedial effect of nicotinamide riboside enhanced mitochondrial function in these muscle stem cells in a SIRT1-dependent manner, affecting cellular respiration, membrane potential, and production of ATP. Accordingly, numerous studies have demonstrated that sirtuins, under nuclear/mitochondrial control, have age-specific effects in determining HSC phenotypes. Based on the evidence accumulated thus far, we propose a clinical intervention for the restoration of aged HSC function by improving mitochondrial function through NAD⁺ precursor supplementation.


Subject(s)
Adenosine Triphosphate , Adult , Adult Stem Cells , Aging , Animals , Bone Marrow , Cell Respiration , Cytoplasm , Diet , Dietary Supplements , Hematologic Neoplasms , Hematopoiesis , Hematopoietic Stem Cells , Humans , Immune System , Incidence , Membrane Potentials , Mice , Mitochondria , Niacin , Niacinamide , Phenotype , Sirtuins , Stem Cells , Tryptophan , Vitamins
16.
Article in Korean | WPRIM | ID: wpr-766373

ABSTRACT

This study examined the sociodemographic factors, health-related habits, chronic diseases, dietary habits, and nutrient intake according to the self-rated health status in a group aged over 65 years by analyzing the nationally representative Korean survey data. A total of 1,510 subjects were analyzed among the participants of the 2016 Korean National Health and Examination Survey (KNHANES). Statistical analyses for complex samples were performed using the SPSS software package (version 19.0) The study subjects were divided into two groups (healthy group vs. unhealthy group) based on their self-rated health status. The percentage of the healthy group was 66.5%. Gender, age, education level, household income, job (P < 0.001, respectively), marital status, and basic living allowance (P < 0.05, respectively) were significant sociodemographic variables of the self-rated health status. Alcohol consumption (P < 0.01), aerobic physical activity, stress, quality of life, not feeling very well, depression and activity restriction (P < 0.001, respectively) were also significant health-related variables of the self-rated health status. Blood glucose, anemia (P < 0.05, respectively), and chewing problems (P < 0.001) were significant chronic disease-related variables of the self-rated health status. Adequate intakes of protein, dietary fiber, phosphorus, thiamin, niacin, vitamin C (P < 0.001, respectively), calcium, sodium, potassium (P < 0.01, respectively), iron, vitamin A, and riboflavin (P < 0.05, respectively) were also significant variables of the self-rated health status. In complex samples multiple logistic regression analysis, the self-rated health status was influenced significantly by the aerobic physical activity (P < 0.01), stress level (P < 0.05), depression (P < 0.001), quality of life (P < 0.001), not feeling very well (P < 0.001), activity restriction (P < 0.001), chewing problem (P < 0.05), and adequate intake of iron (P < 0.05). These results suggest that activity restriction, mental health, adequate iron intake, and physical activity may be associated with the self-rated health status in the elderly.


Subject(s)
Aged , Alcohol Drinking , Anemia , Ascorbic Acid , Blood Glucose , Calcium , Chronic Disease , Depression , Dietary Proteins , Education , Family Characteristics , Feeding Behavior , Humans , Iron , Logistic Models , Marital Status , Mastication , Mental Health , Motor Activity , Niacin , Nutrition Surveys , Phosphorus , Potassium , Quality of Life , Riboflavin , Sodium , Vitamin A
17.
Article in Korean | WPRIM | ID: wpr-766359

ABSTRACT

This study was conducted to investigate the anthropometric data, serum profiles, food intakes frequency, and nutrient intakes of women aged 30–49 years. The subjects were divided into two groups: drinking group and non-drinking group. For the study, we obtained data for analysis from the combined 2008–2015 Korean National Health and Nutrition Examination Survey (KNHANES). Height and weight were 159.2 cm and 58.1 kg in the drinking group as well as 158.1 cm and 57.7 kg in the non-drinking group, respectively. Obesity percentage in the two groups were 22.5% and 24.8%, respectively. HDL-cholesterol (P < 0.001) and Vitamin D (P=0.0248) levels in the drinking group were significantly higher than those of the non-drinking group. In the drinking group, rates of hypertension, myocardial infarction, and diabetes were significantly lower than those of the non-drinking group. Food and nutrient intakes, including energy, water, protein, fat, retinol, thiamin, riboflavin, and niacin, in the drinking group were significantly higher than those of the non-drinking group. In the two groups, energy, water, fiber, calcium, and potassium intakes were low while Na intakes were extremely high considering KDRIs (Dietary Reference Intakes for Koreans). The mean adequacy ratio (MAR) in the two groups was not significant.


Subject(s)
Calcium , Drinking , Female , Humans , Hypertension , Myocardial Infarction , Niacin , Nutrition Surveys , Obesity , Potassium , Riboflavin , Vitamin A , Vitamin D , Water
18.
Article in English | WPRIM | ID: wpr-716440

ABSTRACT

BACKGROUND/OBJECTIVES: Available data suggest that seasonal changes may influence the nutritional status and overall health of elderly individuals. Therefore, this study was conducted to investigate the effects of seasonal changes and related factors on energy and nutrient intake of older adults. SUBJECTS/METHODS: Individuals aged 65 years or over were prospectively enrolled in this single-center study (male: 11, female: 20). Data were collected between May 2013 and February 2014 during winter, spring, summer and autumn. Food consumption and biochemical parameters were taken during each season to assess the seasonal nutrition status of the elderly. Upon analysis of biochemical parameters (retinol, vitamin D and vitamin C), an high-performance liquid chromatography device was utilized whereas an Immulite 2000 device was utilized during analysis of serum folic acid and parathyroid hormone. RESULTS: Fruit, fat, egg and bread consumption varied seasonally in males and females (P < 0.05). During winter, daily energy intake was found to be greater than in other seasons in males (557 kcal) and females (330 kcal) (P < 0.05). Additionally, carbohydrates, vegetable protein, n-3 fatty acid and sodium intake increased in winter, while the n-6/n-3 ratio increased in summer among males (P < 0.05). Dietary fiber and sodium intake in winter, vitamin C, iron and zinc intake in spring, and cholesterol, retinol, vitamin D and niacin intake in autumn were found to be higher in females when compared to other seasons (P < 0.05). Serum parathyroid hormone level was higher in winter, and vitamin D level was higher in autumn in both genders (P < 0.05). In males, blood folic acid level was higher in winter, while vitamin C level was higher in females, and there was no seasonal variation in retinol concentration (P < 0.05). CONCLUSION: Food consumption and biochemical parameters showed significant seasonal variations in older adults. It is not clear if nutrition plans in older adults will benefit from consideration of seasonal changes in eating habits.


Subject(s)
Adult , Aged , Ascorbic Acid , Bread , Carbohydrates , Cholesterol , Chromatography, Liquid , Dietary Fiber , Eating , Energy Intake , Female , Folic Acid , Fruit , Humans , Iron , Male , Niacin , Nutritional Status , Ovum , Parathyroid Hormone , Prospective Studies , Seasons , Sodium , Plant Proteins, Dietary , Vitamin A , Vitamin D , Vitamins , Zinc
19.
Natural Product Sciences ; : 189-193, 2018.
Article in English | WPRIM | ID: wpr-741619

ABSTRACT

Chemical investigation of the ethyl acetate extract of Gibberella moniliformis JS1055 endophytic fungus derived from a halophyte, Vitex rotundifolia, led to the isolation of nine compounds including 7-butyl-6,8-dihydroxy-3(R)-pent-11-enylisochroman-1-one (1), 7-butyl-6,8-dihydroxy-3(R)-pentylisochroman-1-one (2), 7-butyl-6,8-dihydroxy-3(R)-pentylisochroman-1-one (3), 5α,8α-epidioxyergosta-6,9(11),22-trien-3-ol (4), ergosterol peroxide (5), tetradecanoic acid (6), 8-O-methylfusarubin (7), nicotinic acid (8) and adenosine (9). They were identified by extensive spectroscopic data analysis including 1D, 2D (¹H-¹H COSY, HSQC, HMBC) NMR, and ESIMS. All the isolates (1


Subject(s)
Adenosine , Ergosterol , Fungi , Gibberella , Moniliformis , Myristic Acid , Niacin , Salt-Tolerant Plants , Statistics as Topic , Vitex
20.
Article in English | WPRIM | ID: wpr-739622

ABSTRACT

Stroke patients often experience a walking dysfunction caused by decreased mobility, weakened muscular strength, abnormal posture control, and cognitive dysfunction. Anxiety/depression is the most important and prevalent neuropsychiatric complication of stroke survivors. Brain injury and the presence of malnutrition after stroke contribute to metabolic status and clinical outcome of patients. We examined the level of nutrition intake in stroke patients according to their degree of anxiety/depression. The data were obtained from 2013 to 2015 through the Korea National Health and Nutrition Examination Survey (KNHANES). Study subjects were categorized to either a group having no problem of anxiety/depression (n = 274) or a group having a problem of anxiety or depression (n = 104). The EuroQoL-5 Dimensions Health Questionnaire (EQ-5D) index score was derived from the first description of an individual health status based on the EQ-5D classification system, including mobility, self-care, usual daily activities, pain/discomfort, and anxiety/depression. The mean age was 67.4 years in the normal group and 68.0 years in the anxiety or depression group. In the anxiety or depression group, 39.4% were men vs. 53.3% in the normal group. The total energy intake (p = 0.013), riboflavin (p = 0.041), and niacin (p = 0.038) was significantly higher in stroke patients with no anxiety/depression than those in stroke patients with having an anxiety/depression. The group having no problem of anxiety/depression had significantly higher EQ-5D index compared to the group having a problem of anxiety/depression group (p < 0.001) had. The results suggest the association between nutrition intake, usual activities and pain/discomfort status in the stroke patients with having an anxiety/depression.


Subject(s)
Anxiety , Brain Injuries , Classification , Depression , Energy Intake , Humans , Korea , Male , Malnutrition , Niacin , Nutrition Surveys , Posture , Riboflavin , Self Care , Stroke , Survivors , Walking
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