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1.
Article in Chinese | WPRIM | ID: wpr-879031

ABSTRACT

It is the core of the development for Chinese patent medicine enterprises to cultivate large varieties of Chinese patent medicine, and the selection of potential "seed" products is the prerequisite for the cultivation strategy. By constructing the evaluation model from multiple dimensions of value and risk, we can conduct specialized evaluation of Chinese patent medicines to effectively, professionally and objectively select the "seed" products with large variety cultivation potential. In this paper, the establishment of a multidimensional evaluation system would be discussed from the aspects of drug naming and prescription composition, safety risk and supply guarantee of raw materials and medicinal materials, competition situation, access to policy catalogue, scientific and technological support, clinical evidence and recognition, systematical and standardized collection of information on product instructions, quality standards, policy catalogue, scientific and technological literature, market competition and clinical application of Chinese patent medicines. Through the objective evaluation index and the range of objective index, the multi-dimensional evaluation model on values and risks of Chinese patent medicine products was discussed. Based on this model, a batch of Chinese patent medicine products can be quickly and comprehensively analyzed, and quantitative comparison can be formed among different types and fields of products. According to the evaluation results of the model and the comprehensive evaluation of experts, high-quality "seed" products can be selec-ted, laying a solid foundation for the next step of large variety cultivation. With use of this model, we can further clarify the external competitive advantages and internal priority levels of each product, and provide support for enterprises to optimize product structure and improve product strategic layout.


Subject(s)
China , Drugs, Chinese Herbal/adverse effects , Medicine, Chinese Traditional , Nonprescription Drugs/adverse effects , Quality Control
2.
Article in English | IMSEAR | ID: sea-144762

ABSTRACT

Background & objectives: Several studies have reported adverse drug events ranging from 5 to 35 per cent in all age group from outpatient setting. However, adverse drug reactions (ADRs) particularly among a large sample of ambulatory elderly patients in India has not been reported. This study has attempted to identify ADRs and assessed their causality, preventability and severity, and also their risk factors in Indian ambulatory elderly patients. Methods: A 2 year long term prospective study included 4005 ambulatory elderly patients (60 yr or above; either sex) at a public teaching hospital. Suspected ADRs were assessed for causality, preventability and severity using Naranjo's probability scale, modified Schumock and Thornton's criteria, and modified Hartwig's criteria, respectively. Results: Of the total 4005 prescriptions, 406 were identified with ADRs, giving the occurrence of 10 per cent ADRs in elderly. The total number of ADRs was 422 in 406 prescriptions. Type A ADRs accounted for 46 per cent of the total ADRs. Majority of the ADRs (88.6%) were classified as ‘probable’. The definitely preventable reactions were 22 per cent. The percentage of moderate reaction was 16 per cent. Only 1.6 per cent ADRs was severe in nature. The most common type of ADR was peripheral oedema. The most commonly offending class of drug was cardiovascular drugs (57.6%). Using logistic regression analysis, the risk factors which contributed to ADRs were age above 80 yr (OR=1.7), prescription of multiple drugs (OR=1.8), longer duration of treatment (OR=2.28) and multiple diagnoses (OR=1.8). Interpretation & conclusions: In this study, 10 per cent ambulatory elderly patients were found to have ADRs. This indicates that the elderly patients should be closely monitored for ADRs, to avoid clinically significant harmful consequences. The awareness of risk factors of ADRs would help physicians to identify elderly patients with greater risk of ADRs and, therefore, might benefit from ADRs monitoring and reporting programme.


Subject(s)
Adverse Drug Reaction Reporting Systems , Aged , Aged, 80 and over , Ambulatory Care/statistics & numerical data , Drug-Related Side Effects and Adverse Reactions/epidemiology , Drug-Related Side Effects and Adverse Reactions/etiology , Female , Humans , India/epidemiology , Male , Nonprescription Drugs/adverse effects , Prescription Drugs/adverse effects , Risk Factors
3.
Medical Principles and Practice. 2010; 19 (3): 182-187
in English | IMEMR | ID: emr-98433

ABSTRACT

To study the prevalence and attitude of using nonprescription corticosteroids [oral or parenteral formulation of glucocorticosteroids] in Basrah, Iraq. A face-to-face model structured interview was used to collect information from 682 patients between January 2006 and December 2008. The following information was obtained: age, gender, marital status, smoking, drinking of alcohol, occupation, educational level, social class and place of residence. Of the 682 [2.6%] subjects using nonprescription corticosteroids most were females: 471 [69%]; married: 567 [83%]; of low social class: 430 [63.1%]; lived in the city center: 475 [69.6%]. The majority [569, 83.5%] thought that corticosteroid use was safe and 463 [68.0%] did not feel guilty for using such medications. About half of them [377, 55.3%] were still using drugs at the time of presentation. Three hundred and fifty-seven [52.4%] reported that physicians advised them for the first time to use corticosteroids and the remaining 325 [42.2%] used it to become beautiful or marry. Three hundred and sixty-four [53.4%] patients obtained the drug from the pharmacy and 252 [36.9%] from street vendors. Weight gain was the main indication for use in 342 [50.1%] patients. Almost all had some features of corticosteroid side effects. This study showed high use of nonprescription corticosteroid in Basrah, Iraqi. We therefore recommend educational programs to alert the population of the untoward side effects of corticosteroids


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged , Nonprescription Drugs/adverse effects , Health Knowledge, Attitudes, Practice , Adrenal Cortex Hormones , Sex Factors , Outpatient Clinics, Hospital/statistics & numerical data , Age Factors , Socioeconomic Factors , Cross-Sectional Studies
4.
Braz. oral res ; 23(supl.1): 64-70, 2009.
Article in English | LILACS | ID: lil-528431

ABSTRACT

Tooth discoloration is commonly found in the dental clinic and tooth bleaching has been considered the preferred esthetic alternative, being more conservative, safe and with predictable results. Supervised home-use of 10 percent Carbamide Peroxide (CP) bleaching with custom-trays is the most common bleaching procedure dispensed by dentists to their patients. The good results obtained with this technique stimulated the flourishing of new products and techniques. Over-the-counter (OTC) bleaching products appeared as a low-cost alternative to bleach discolored teeth without dentist supervision. Different OTC products are available in supermarkets, drug stores or on the Internet, including rinses, paint-on brushes, toothpastes, chewing guns, dental floss, and whitening strips. There is lack of clinical evidence regarding the safety and effectiveness of these products, being most of the studies supported by the manufacturers'. Basically, toothpastes, chewing gums, and dental floss are removal agents of superficial stains. Rinses and paint-on brushes with low levels of hydrogen peroxide have some whitening effect, but without clinical relevance. Strips present similar esthetic results and side-effects, compared to bleaching with 10 percent CP using trays; however, the studies have financial support from the manufacturers and were based on short term evaluations. Legislation varies widely in different countries regarding OTC dental bleaching. Concerns have appeared due to the potential abusive use of these self-medication agents, especially in young patients, with potential harmful results. Dentists should be acquainted with this kind of products to be able to inform their patients. In conclusion, there is a need for independent clinical trials to provide sufficient evidence regarding the use of OTC bleaching products.


Subject(s)
Humans , Dental Devices, Home Care/standards , Nonprescription Drugs/administration & dosage , Oxidants/administration & dosage , Peroxides/administration & dosage , Tooth Bleaching/standards , Urea/analogs & derivatives , Chewing Gum , Clinical Trials as Topic , Dental Devices, Home Care/economics , Dentifrices/administration & dosage , Hydrogen Peroxide/administration & dosage , Mouthwashes/administration & dosage , Nonprescription Drugs/adverse effects , Nonprescription Drugs/economics , Oxidants/adverse effects , Peroxides/adverse effects , Self Medication , Treatment Outcome , Toothpastes/administration & dosage , Urea/administration & dosage , Urea/adverse effects
6.
Salud pública Méx ; 50(supl.4): s453-s462, 2008. ilus
Article in Spanish | LILACS | ID: lil-500419

ABSTRACT

OBJETIVO: Se presenta el método para diseñar etiquetas de medicamentos centrados en el usuario, aplicado a un analgésico pediátrico. MATERIAL Y MÉTODOS: El Communication Research Institute (CRI) de Australia desarrolló este método, consistente en seis etapas que cubren todos los aspectos relacionados con el diseño de una etiqueta. Para aplicarlo por primera vez al analgésico pediátrico en México, y en sociedad con el CRI, el Centro de Estudios Avanzados de Diseño realizó diversos ajustes, como la modificación del nivel de desempeño o la inclusión de preguntas al protocolo. RESULTADOS: La aplicación de este método a la etiqueta del analgésico mejoró sustancialmente la localización y comprensión de la información del medicamento en "usuarios en riesgo", lo cual garantiza que el público general obtendrá la información adecuada para automedicarse correctamente. CONCLUSIONES: La aplicación del método llevó a firmar, en 2005, las Guías de etiquetado para medicamentos de libre acceso en México.


OBJECTIVE: This study presents the application of a method to design medicine labels centred in the user and applied to a Mexican children's analgesic. MATERIAL AND METHODS: The method was developed by the Communication Research Institute (CRI) of Australia and consists of six stages that thoroughly consider all aspects related to medicine labels. This method was applied for the first time in Mexico by CRI and by the Centre for Advanced Studies in Design (CEAD), but it required a number of modifications to adjust it, like modifying the label's performance requirements and incorporating different questions to the protocol. RESULTS: The application of this method to the children's analgesic improved significantly the localization and comprehension of the information by "users at risk", which guarantees that the general public will get adequate information for correct self-medication. CONCLUSIONS: The application of this method led to sign the Guides for OTC labels in Mexico in 2006.


Subject(s)
Adult , Child , Child, Preschool , Humans , Infant , Male , Anti-Inflammatory Agents, Non-Steroidal , Drug Labeling/methods , Nonprescription Drugs , Patient Education as Topic/methods , Self Medication , Anti-Inflammatory Agents, Non-Steroidal/administration & dosage , Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Anti-Inflammatory Agents, Non-Steroidal , Comprehension , Educational Status , Health Knowledge, Attitudes, Practice , Medication Errors/prevention & control , Nonprescription Drugs/administration & dosage , Nonprescription Drugs/adverse effects , Nonprescription Drugs , Parents/psychology , Reading , Risk
7.
Article in Korean | WPRIM | ID: wpr-182811

ABSTRACT

BACKGROUNDS/AIMS: In Korea, interests in health and health care costs have been increased along with the increase of mean survival rate and income level. The aim of this study is to investigate the actual condition of drug medication and burden of health care cost. METHODS: A total of 1,434 subjects in four tertiary medical centers were enrolled in this study. The questionnaires were obtained between March 2005 and September 2005. Based on this information, the actual condition of drug medication and health care cost were analyzed. RESULTS: The mean age of the subjects was 55.0+/-11.4 years (16-87 years). The male and female ratio was 1.74:1. The subjects with drug medication except for doctor's prescription are presently 26.6% and were 40.9% in the past. Traditional medicine (39.6%) and health food (29.9%) are more frequently used than herbal medicine (5.8%) and medical supplies (4.2%) now. In the past, herbal medicine (14.6%) was more frequently used compared with the present. The side effects of drug medication were developed in 90 subjects (7.5%). The total mean health care costs were 895,000 won/year, the herbal medicine, 834,000 won/year, the health food, 950,000 won/year, and the traditional medicine, 324,000 won/year. CONCLUSIONS: In this study, the subjects with other drug medications without doctor's prescription were as high as ever. The frequency of the use of the herbal medicine was decreased. However, the frequency for the use of the health food and traditional medicine have relatively increased. The side effects and additional large amounts of health care costs were occurred.


Subject(s)
Adolescent , Adult , Adverse Drug Reaction Reporting Systems , Aged , Aged, 80 and over , Dietary Supplements/adverse effects , Female , Health Care Costs , Health Surveys , Humans , Korea , Liver/injuries , Liver Diseases/chemically induced , Male , Middle Aged , Nonprescription Drugs/adverse effects , Plants, Medicinal/adverse effects , Self Medication/adverse effects
8.
Article in English | IMSEAR | ID: sea-46602

ABSTRACT

Over the counter (OTC) drugs are commonly used by pregnant women. Most OTC drugs are safe in pregnancy but some have unproven safety and may adversely affect the growing foetus. The safety profile of some of the medication may change according to the gestational age of the foetus. Because an estimated 10% or more of the birth defects results from maternal drug exposure, the US Food and Drug Administration (FDA) has assigned a risk category to each drugs. Among the commonly used OTC drugs Acetaminophen, Chlorpheniramine, Kaolin and Pectin preparations and most antacids have a good safety record. The drugs like H2 blockers; Pseudoephedrine and Atropine/Diphenoxylate should be used with caution. The risk and benefit while using OTC drugs in pregnancy has to be assessed.


Subject(s)
Abnormalities, Drug-Induced/etiology , Female , Humans , Lactation/metabolism , Maternal-Fetal Exchange , Nonprescription Drugs/adverse effects , Pregnancy , Risk Factors , United States , United States Food and Drug Administration
9.
Rev. ciênc. farm ; 25(2): 135-148, 2004.
Article in Portuguese | LILACS | ID: lil-418904

ABSTRACT

Os laxativos disponíveis no mercado brasileiro são enquadrados pela legislação em vigor na categoria de Venda Sem Prescrição Médica. Os consumidores, consequentemente, realizam automedicação de laxativos, sem considerarem as diferenças no diagnóstico da constipação e a segurança dos laxativos. Avaliar o enquadramento dos laxativos na categoria de Venda Sem Prescrição Médica, mediante revisão bibliográfica sobre constipação e segurança dos laxativos, considerando as especialidades farmacêuticas existentes no Brasil em 2003. Levantamento das especialidades farmacêuticas laxativas existentes no Brasil em 2003, através de publicações específicas. Revisão bibliográfica sobre constipação, segurança dos laxativos e categoria de venda dos medicamentos, através da Internet e livros da farmacologia. Em 2003 estão disponíveis 61 especialidades farmacêuticas laxativas no Brasil, todas enquadradas nas categorias de "Venda Sem Prescrição Médica". O tratamento ideal da constipação depende do entendimento da fisiopatologia desta condição. Foram encontrados dados controversos sobre a associação entre o uso de laxativos estimulantes e câncer colorretal ou disfunção neuromotora do intestino. Os dados controversos são preocupantes diante do número elevado de laxativos encontrados no mercado, além de serem considerados pela legislação atual, que enquadra todos os laxantes na categoria de Venda Sem Prescrição Médica, independentemente do modo de ação


Subject(s)
Cathartics/adverse effects , Cathartics/pharmacology , Cathartics/standards , Nonprescription Drugs/adverse effects , Nonprescription Drugs/standards , Self Medication/adverse effects , Constipation , Colorectal Neoplasms/complications
10.
Article in English | IMSEAR | ID: sea-43187

ABSTRACT

BACKGROUND: Common colds are usually treated by the patients themselves with over-the-counter (OTC) cold medications. Many cough and cold remedies are available and sold freely without prescription. The authors conducted a study to compare the efficacy, adverse effects, the quality of life (QOL) and the patient's opinion and appreciation on the drugs (POD) between Dayquil/Nyquil and Actifed DM plus paracetamol syrup. METHOD: In this prospective, investigator-blinded clinical trial, 120 patients, aged between 15 and 60 years old, with common colds within 72 hours, who accepted the trial and gave informed written consent, were randomized into two treatment groups. One patient was excluded due to evidence of bacterial infection. Fifty-nine patients were treated with Dayquil/Nyquil (D/N group), while the other 60 patients had Actifed DM plus paracetamol (ADM/P group) for three days. On day 1 the patient's demographic data (sex, age, body weight, blood pressure, co-existing diseases/conditions, drug use, and allergy to any drugs), the most prominent symptoms and its duration were recorded. All patients were screened for bacterial infection by physical examination, complete blood count and sinus radiographs. The symptoms (nasal obstruction, rhinorrhea, sneezing, cough, sore throat, fever and headache) and signs (injected nasal mucosa, nasal discharge and pharyngeal discharge) were scored, based on 4-point scale (0 to 3), on days 1 and 4. Changing of the symptoms and QOL were recorded on the diary card. The patient's opinion and appreciation on the drugs (POD) was assessed on day 4. The effectiveness (the ability to lessen the symptoms and signs), QOL and POD between two treatments were compared. RESULTS: The demographic data between the two groups were similar. The four most common prominent symptoms of common colds in our series were cough (47.9%), sore throat (26.17%), rhinorrhea (8.4%) and headache (8.4%). However, both treatments were equally effective in lessening the symptoms (P = 0.426) and signs (P = 0.716) of common cold from days 1 to 4. The adverse effects were significantly higher in ADM/P group than in D/N group (p = 0.006). In contrast, QOL in terms of alertness, freshness and sound sleep improved from day 1 to day 3 in both treatments, but the overall day-3 score was significantly higher in the D/N group than the ADM/P group (1.85 +/- 1.83; 1.25 +/- 1.94: p = 0.024). POD in terms of convenience, flavour of drug, effectiveness of the drug and a need to repeat the drug assessed on day 4, was also significantly higher in the D/N group than the ADM/P group (10.68 +/- 2.56; 8.92 +/- 2.27: p < 0.001). CONCLUSION: Dayquil/Nyquil are as effective as Actifed DM plus paracetamol in controlling the symptoms and signs of the common cold, but have fewer adverse effects. The quality of life assessed during the use of the drugs was significantly higher in the Dayquil/Nyquil group, and according to the patients, they prefered Dayquil/Nyquil more than Actifed DM plus paracetamol.


Subject(s)
Acetaminophen/adverse effects , Adolescent , Adult , Common Cold/drug therapy , Dextromethorphan/adverse effects , Doxylamine/adverse effects , Drug Combinations , Ephedrine/adverse effects , Expectorants/adverse effects , Female , Humans , Male , Middle Aged , Nonprescription Drugs/adverse effects , Patient Satisfaction , Promethazine/adverse effects , Prospective Studies , Quality of Life , Triprolidine/adverse effects
11.
Pediatr. mod ; 36(4): 177-: 180-: 182-178, 180, 181, abr. 2000.
Article in Portuguese | LILACS | ID: lil-311087

ABSTRACT

O presente estudo objetivou analisar a conduta dos balconistas de 25 farmácias da zona urbana de Santa Maria (RS), escolhidas aleatoriamente, em relaçäo ao tratamento da otite média aguda em crianças, patologia frequente na prática diária do otorrinolaringologista e do pediatra. Os resultados mostraram que em apenas oito farmácias foi dada orientaçäo para procurar um médico (32 por cento). No entanto, em sete desses casos o balconista se propôs a vender alguma medicaçäo. Das 24 farmácias onde houve indicaçäo de medicamentos, apenas três balconistas "prescreveram" antibióticos (12,5 por cento). Desses, nenhum o fez de forma totalmente correta. Os autores concluem ser fundamental que haja uma maior conscientizaçäo da populaçäo e dos próprios balconistas em relaçäo aos riscos que podem advir do tratamento inadequado da otite média aguda.


Subject(s)
Humans , Child , Otitis , Pharmacies , Nonprescription Drugs/adverse effects , Interviews as Topic
12.
Braz. j. infect. dis ; 3(5): 180-3, Oct. 1999.
Article in English | LILACS | ID: lil-254762

ABSTRACT

It i an accepted fact that, in many countries, pharmacies are the predominat source of medical advice over-the-counter drugs, and supplies of "prescription-only" drugs for sale without a prescription. To assess the activities conducted by pharmacists or pharmacy counter assistants in response to a common health problem, a cross-sectional study was done at 114 pharmacies in Porto Alegre, Brazil. A fictitious case-history of cough was used by trained personnel entering the pharmacy and the subsequent activities by the pharmacist or pharmacy counter assistant were analyzed. Some kind of medication was provided in 101 (88.5 percent)of the pharmacies. Pharmacists gave medication in 80 percent of pharmacies, and pharmacy assistants in 95.5 percent (p<0.03). The class of medication most frequently dispensed was the expectorants (97 times, 92.4 percent), however, systemic antibiotics were provided in 11 pharmacies (10.5 percent). Of note, the pharmacists provided antibiotics more frequently than did pharmacy assistants (p=0.016). We conclude that pharmacy advice and symptomatic medical care (expectorants) are very common and that pharmacy assistants are more likely than pharmacists to provide medication. Of concern, when pharmacists were the drug dispensers of antibiotics which should be provided by prescription only, drugs were provided without proper diagnosis, and often incorrect dosages. This reflects a pontentially dangerous practice in need of careful evaluation, education and supervision.


Subject(s)
Anti-Bacterial Agents , Antitussive Agents/therapeutic use , Cough/drug therapy , Expectorants/therapeutic use , Nonprescription Drugs/administration & dosage , Nonprescription Drugs/adverse effects , Drug Prescriptions , Self Administration , Drug Monitoring/standards , Pharmacies/standards
13.
Rev. méd. Hosp. Säo Vicente de Paulo ; 10(23): 35-7, jul.-dez. 1998. graf
Article in Portuguese | LILACS | ID: lil-238353

ABSTRACT

Os autores realizaram pesquisa em 27 farmácias de Passo Fundo, apresentando duas situações clínicas fictícias: um caso de diarréia em adulto e um caso de rinite alérgica em criança de 4 anos. De todos os balconistas consultados, apenas 8 (29,6 por cento) orientaram procurar um médico. Vinte e três (85,19 por cento) prescreveram tratamento para rinite alérgica e somente um deixou de receitar medicação para diarréia...


Subject(s)
Humans , Nonprescription Drugs/adverse effects , Pharmacies
17.
Rev. Fac. Med. Univ. Nac. Nordeste ; 12(2): 6-10, 1995. ilus, tab
Article in Spanish | LILACS | ID: lil-241811

ABSTRACT

Con el objetivo de investigar la magnitud de la prescripción de medicamentos en las farmacias sin receta médica se realizó la visita a 50 establecimientos farmacéuticos de la ciudad de Corrientes seleccionados al azar. La investigación consistió en la simulación de una enfermedad por un grupo de alumnos de la Cátedra de Semiotecnia y Fisiopatología, que concurrían a las farmacias solicitando un tratamiento. Del análisis de los resultados obtenidos se observó que en 45/50 (90 por ciento) farmacias se realizó una prescripción de medicamentos, y solo 5/50 (10 por ciento) indicaron específicamente una consulta médica. Ante la requisitoria, 10 de las 45 que medicaron (20 por ciento) indicaron la consulta luego de un período de tratamiento. Del análisis de las indicaciones, 42 de las 45 (93,33 por ciento) son de medicamentos catalogados como de "venta bajo receta". 86,67 por ciento fueron de antibióticos, en monodrogas o en combinaciones fijas, siendo la indicación más frecuente la de una asociación de uno o dos antibióticos con un analgésico urinario. Las drogas más indicadas fueron combinaciones de dos drogas un quimioterápico con una analgésico urinario (37,78 por ciento), y una combinación de tres drogas o dosis fijas (35,55 por ciento), de dos quimioterápicos con un analgésico urinario. No se pudo establecer una relación de costo con la indicación, ya que los medicamentos indicados no eran los más costosos. Se analizan aspectos relacionados al problema estudiado y se realizan propuestas a fin de tratar de conseguir una utilización más racional de los medicamentos


Subject(s)
Humans , Male , Female , Liability, Legal/economics , Nonprescription Drugs/supply & distribution , Pharmacies/statistics & numerical data , Argentina , Commerce/statistics & numerical data , Economics, Pharmaceutical/statistics & numerical data , Pharmacists/trends , Nonprescription Drugs/adverse effects , Pharmacy Technicians/trends
18.
Carta med. A.I.S. Boliv ; 8(2): 49-55, 1994.
Article in Spanish | LILACS | ID: lil-169951

ABSTRACT

Sintetiza las numerosas contribuciones de los medicamentos y la industria, a la salud de la poblacion mundial, en ambitos medico y economico. Considera los especiales problemas de los medicamentos consumidos por gente saludable, presentando una retrospectiva y cuantitativa vision de los efectos adversos a estos farmacos. Cuestiona las comunes interrogantes: de proque la gente particularmente en el tercer mundo- sigue sufriendo a causa de medicamentos y pagando por inefectivos, inapropiados, innecesrios e inseguros farmacos. provee informacion sobre las consecuencias de la practica no etica de promocion de medicamentos por parte de la Industria Farmaceutica. Alerta sobre la existencia de medicamentos falsos que no solo provocan serios y negativos resultados, como el desperdicio de recursos, sino en la salud de la poblacion, principalmente en paises poblres. Muestra una vez mas, la importancia de adoptar una Politica Nacional de Medicamentos, a fin de resolver estos problemas


Subject(s)
Drug Evaluation/adverse effects , Drug Industry/legislation & jurisprudence , Drug Industry/trends , Bolivia , Drug Contamination/prevention & control , Drug Industry/trends , Nonprescription Drugs/adverse effects
19.
West Indian med. j ; 42(2): 77-8, June 1993.
Article in English | LILACS | ID: lil-130596

ABSTRACT

A case of Cushing's syndrome is described in a woman who self-treated psoriasis with a variety of potent tropical glucocorticoids over 15 years. She was successfully weaned off corticosteroids and was treated with alternative anti-psoriatic drugs. The disappearance, nine months later, of most features of Cushing"s syndrome, and the normal supression of cortisol in response to dexamethasone, excluded endogenous hypercorticolism. The apparent widespread availability across the counter of potent corticosteriods is a cause of concern.


Subject(s)
Humans , Adult , Female , Anti-Inflammatory Agents/adverse effects , Cushing Syndrome/etiology , Nonprescription Drugs/adverse effects , Psoriasis/drug therapy , Self Medication , Substance-Related Disorders
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