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1.
Pesqui. vet. bras ; 40(8): 621-629, Aug. 2020. tab, ilus
Article in English | ID: biblio-1135666

ABSTRACT

This study aimed to quantify nasosinusal neoplasms diagnosed in dogs in 20 years (2000-2019) and characterize the main clinical, macroscopic, and histological aspects of these neoplasms. The sex, breed, age, skull conformation, the main clinical signs, and the anatomopathological characteristics (distribution, macroscopy, and histology) were computed. During this period, 49 dogs were affected by neoplasms in these regions, totaling 50 neoplasms (one dog had two neoplasms of different locations and histogenetic origins). Similar amounts of mixed-breed dogs (25/49) and purebred dogs (24/49) were affected, these distributed in 16 breeds. Among purebreds, it was noted that dogs with mesocephalic cranial conformation (12/24) were the most affected, followed by dolichocephalic (10/24) and brachycephalic (2/24). There were 22 cases in males and 27 in females, making a proportion of 1:1.23. There was an age variation from 11 months to 16 years old. The epithelial neoplasms have occurred in older dogs compared to those of other histogenic origins (mesenchymal and other origins/round cells). The main clinical signs were similar between the histogenetic categories, related to the involvement of the upper respiratory tract, sometimes accompanied by nervous signs (when there was brain invasion of nasal neoplasms or vice versa). The possible origin site was mostly in the nasal cavity concerning the paranasal sinuses (and other locations). Invasions occurred in different tissues adjacent to the nasal cavity and paranasal sinuses, resulting in cranial and facial deformities (21/49). The frequency was 48% of epithelial neoplasms, 32% of mesenchymal neoplasms, and 10% of neoplasms with other origins and round cells. The neoplasms most frequently observed, in decreasing order of frequency, were: adenocarcinoma (9/50), squamous cell carcinoma (9/50), transmissible venereal tumor (5/50), osteosarcoma (5/50), chondrosarcoma (4/50), and undifferentiated sarcoma (4/50). Through this study, it was possible to establish the frequency of these neoplasms in 20 years and their clinical, macroscopic, and histological characteristics.(AU)


Este estudo teve como objetivo quantificar os neoplasmas nasossinusais diagnosticados em cães em 20 anos (2000-2019) e caracterizar os principais aspectos clínicos, macroscópicos e histológicos desses neoplasmas. Foram computados sexo, raça, idade, conformação do crânio, principais sinais clínicos e características anatomopatológicas (distribuição, macroscopia e histologia). Nesse período, 49 cães foram acometidos por neoplasmas nessas regiões, totalizando 50 neoplasmas (um cão tinha dois neoplasmas de localização e origens histogenéticas distintas). Foram acometidas quantidades semelhantes de cães sem raça definida (25/49) e de cães com raça definida (24/49), estes distribuídos em 16 raças. Entre os cães com raça definida, notou-se que os cães com conformação craniana mesocefálica (12/24) foram os mais acometidos, seguidos pelos dolicocefálicos (10/24) e braquicefálicos (2/24). Foram observados 22 casos em machos e 27 em fêmeas, perfazendo a relação de 1:1,23. Ocorreu uma variação de idade de 11 meses a 16 anos; tendo os neoplasmas epiteliais ocorrido em cães mais velhos quando comparado aos de outras origens histogênicas (mesenquimais e outras origens/células redondas). Os principais sinais clínicos foram semelhantes entre as categorias histogenéticas, sendo relacionados ao comprometimento do trato respiratório superior, por vezes acompanhados de sinais nervosos (quando houve invasão encefálica de neoplasmas nasais ou vice-versa). O possível local de origem em sua maioria foi na cavidade nasal em relação aos seios nasais (e de outras localizações). Ocorreram invasões para diferentes tecidos adjacentes à cavidade nasal e seios paranasais, tendo como consequência deformidades cranianas e faciais (21/49). A frequência foi de 48% de neoplasmas epiteliais, 32% de neoplasmas mesenquimais e 10% de neoplasmas com outras origens e de células redondas. Os neoplasmas mais frequentemente observados, em ordem decrescente de frequência, foram: adenocarcinoma (9/50), carcinoma de células escamosas (9/50), tumor venéreo transmissível (5/50), osteossarcoma (5/50), condrossarcoma (4/50) e sarcoma indiferenciado (4/50). Com isso, pode-se estabelecer a frequência desses neoplasmas em 20 anos, bem como suas características clínicas, macroscópicas e histológicas.(AU)


Subject(s)
Animals , Dogs , Paranasal Sinuses/pathology , Paranasal Sinus Neoplasms/veterinary , Paranasal Sinus Neoplasms/epidemiology , Nose Neoplasms/pathology , Nose Neoplasms/veterinary , Nose Neoplasms/epidemiology , Dog Diseases/epidemiology , Nasal Cavity , Carcinoma/veterinary
3.
Pakistan Journal of Otolaryngology-Head and Neck Surgery. 2011; 27 (2): 37-38
in English | IMEMR | ID: emr-118262

ABSTRACT

To analyse the sex and age incidences, clinical presentations and histopathological picture of the benign tumours of nose and paranasal sinuses. Prospective, Longitudinal, Descriptive. GMS Memorial Academy of ENT and HNS,TUTH, Kathmandu, Nepal. 2 years, September 2008 to August 2010. All cases of benign masses of nose and paranasal sinuses who visited the Outpatient department and were undergoing surgical intervention were included. The histological proven malignant masses were excluded from the study. Out of 49 patients, majority of the patients were between 13-20 years [34.69%]. Male:female ratio was 3.9:l.The most common presenting symptoms were unilateral nasal obstruction and nasal bleeding [65.29%]. Inverted papilloma and angiofibroma were the most common tumours [42.84%]. All masses of nose and paranasal sinuses should be subjected to histopathological examination and followed up for two years for assessment of outcome of treatment and monitoring recurrences


Subject(s)
Humans , Adolescent , Young Adult , Male , Female , Paranasal Sinus Neoplasms/pathology , Paranasal Sinus Neoplasms/diagnosis , Nose Neoplasms/diagnosis , Paranasal Sinus Neoplasms/epidemiology , Nose Neoplasms/epidemiology , Prospective Studies
4.
Rev. otorrinolaringol. cir. cabeza cuello ; 70(1): 43-48, abr. 2010. ilus, tab
Article in Spanish | LILACS | ID: lil-577222

ABSTRACT

Introducción: El papiloma invertido es un tumor benigno que afecta fosas nasales y senos paranasales; histológicamente se clasifica en oncocítico, invertido y fungiforme. Los signos y síntomas son obstrucción nasal unilateral, rinorrea, cefalea, epistaxis, anosmia. El diagnóstico de certeza es por anatomía patológica; se utilizan además métodos de diagnóstico por imagen para determinar la extensión tumoral. Existe cierto porcentaje de asociación de esta patología al carcinoma escamoso. El tratamiento es quirúrgico. Objetivo: Evaluar las características clínicas y quirúrgicas de papilomas invertidos operados en la Cátedra de ORL del Hospital de Clínicas de la Facultad de Ciencias Médicas, Universidad Nacional de Asunción, Paraguay (UNA). Material y método: En este trabajo de carácter observacional y descriptivo se estudiaron los casos de papiloma invertido operados en el Hospital de Clínicas entre los años 1994 a 2008, mediante revisión de fichas de casos consecutivos, analizando las cirugías realizadas. Resultados: Treinta casos de los cuales la mayoría fue de estadio II y III de Krause, con una recidiva global del 30 por ciento con una malignización del 17 por ciento. Discusión: En esta serie de pacientes se vio tumores con poca extensión pero con una transformación maligna presente, elevándolos al estadio IV de Krause. Conclusión: Se sugiere intentar la mayor radicalidad posible siempre con el total consentimiento y conocimiento del paciente.


Introduction: Inverted papilloma is a benign tumor that affects nasal cavity and Para nasal sinuses; histologically classified as oncecitas, inverted papillomas and fundiform or exophytic. Signs and symptoms include unilateral nasal obstruction, rhino rhea, headache, epitasis, and anosmia. The certainty diagnosis is given by pathology and in diagnosis are used imaging methods to determine the extent of the tumor. There is a certain percentage of association of this pathology with squamous carcinoma. The treatment is surgical. Aim: To evaluate the clinical and surgical characteristics of inverted papillomas that were operated in the Department of ENTin the Hospital School of Medical Sciences, UNA. Material and method: In this observational and descriptive work were studied cases of inverted papilloma operated at the Hospital from 1994 to 2008, by reviewing records of consecutive cases and analyzing the surgeries performed. Results: 30 cases in which the majority were Stage II and III of Krause, with an overall of 30 percent, relapse with a malignancy of 17 percent. Discussion: In this series of patients we observed tumors with low extension but with malignant transformation which elevated them to stage IVKrause. Conclusión: We suggest trying the most radical possible surgery provided with the fuII consent and knowledge of the patient.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Nose Neoplasms/surgery , Nose Neoplasms/pathology , Papilloma, Inverted/surgery , Papilloma, Inverted/pathology , Age and Sex Distribution , Cross-Sectional Studies , Neoplasm Staging , Nose Neoplasms/epidemiology , Papilloma, Inverted/epidemiology , Otorhinolaryngologic Surgical Procedures/methods , Neoplasm Recurrence, Local/epidemiology , Signs and Symptoms
5.
Article in English | IMSEAR | ID: sea-46564

ABSTRACT

OBJECTIVE: To evaluate the clinicopathological profile of sinonasal inverted papilloma in a tertiary referral center in eastern part of Nepal. METHODS: A prospective study consisting of total 28 histologically proven cases of sinonasal inverted papilloma was conducted in the ENT department of the center. The study period was from April 2002 to November 2005. RESULT: Out of 28 cases studied, 21 were males and 7 were females with male to female ratio of 3:1. The highest incidence was seen in the 5th and 6th decades of life. The duration of symptoms varied from 5 months to 20 years with mean duration of 3.9 years. The lateral nasal wall and nasal cavity involvement was seen in all 28 cases. Maxillary sinus was involved in 27(96.4%) subjects followed by ethmoid (20), sphenoid (10) and the frontal sinus (7). The principle presenting symptom was nasal obstruction seen in 96.4% of the patients. Twenty two cases were treated by lateral rhinotomy with medial maxillectomy while, orbital exenteration was done in two cases. Associated carcinoma was noticed in 10.15% of all the subjects studied. CONCLUSION: Sinonasal papilloma mostly presented in fifth to six decades of life mainly affecting the male patients. Majority of the patients were treated by lateral Rhinotomy with medial maxillectomy surgery. Early presentation would have given chances for endoscopic surgery.


Subject(s)
Adult , Age Distribution , Female , Humans , Male , Middle Aged , Nasal Cavity , Nepal/epidemiology , Nose Neoplasms/epidemiology , Papilloma, Inverted/epidemiology , Paranasal Sinuses , Prospective Studies , Sex Distribution , Young Adult
6.
Article in English | WPRIM | ID: wpr-162672

ABSTRACT

A high incidence of a T cell phenotype of sinonasal lymphomas in other Asian countries has been associated with a high incidence of Epstein Barr virus (EBV) infection. We analyzed 13 sinonasal and 18 Waldeyer's ring lymphomas for the prevalence of EBV encoded RNA (EBER) using a sensitive and specific in situ hybridization. In addition, we examined the relationship of histologic findings and immunophenotype as well as the location of the lymphomas to the presence of EBV. The EBER was detected in each of 12 sinonasal lymphomas with a T cell immunophenotype. One B cell sinonasal lymphoma was EBER negative. Four of 18 Waldeyer's ring lymphomas were positive for EBER, including two T cell lymphomas. Two of 16 B cell Waldeyer's ring lymphomas were EBER positive. Morphologically, 11 of 20 diffuse large cell lymphomas, 2 diffuse mixed small and large cell lymphomas, 2 of 4 immunoblastic lymphomas and 1 lymphoplasmacytic lymphoma were EBER positive. Four follicular large cell lymphomas were EBER negative. A characteristic angiocentric or angiodestructive pattern was found in most T cell lymphomas and EBER positive cases. These findings indicate that EBV infection is more strongly associated with the T cell immunophenotype, angiocentric pattern and sinonasal location of the lymphoma.


Subject(s)
Adult , Aged , B-Lymphocytes/immunology , Female , Herpesviridae Infections/virology , Herpesvirus 4, Human/genetics , Humans , Immunophenotyping , In Situ Hybridization , Incidence , Lymphoid Tissue/virology , Lymphoma, Non-Hodgkin/epidemiology , Male , Maxillary Neoplasms/epidemiology , Middle Aged , Nasopharyngeal Neoplasms/epidemiology , Nose Neoplasms/epidemiology , Prevalence , RNA, Viral/analysis , Survival Rate , T-Lymphocytes/immunology , Tonsillar Neoplasms/epidemiology , Tumor Virus Infections/virology
7.
West Indian med. j ; 36(3): 181-3, Sept. 1987. ilus
Article in English | LILACS | ID: lil-70844

ABSTRACT

Leiomyoma of the nasal cavity is described in a 32-year-old Trinidadian woman. This is the first such case to be reported in the Commonwalth Carbbean, and the world literature


Subject(s)
Adult , Humans , Male , Female , Leiomyoma/epidemiology , Nose Neoplasms/epidemiology , Nasal Cavity , Trinidad and Tobago
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