ABSTRACT
Pleomorphic adenoma is the most common benign neoplasm of salivary glands. Their common location is in parotid gland, however, a lower percentage of these tumors might occur in minor glands. The epidemiology of this tumor shows that adults are the most affected, with rare occurrence in children or adolescents. We present the case report of pleomorphic adenoma located on the palate of a 10 year old. Excisional biopsy of the lesion followed by histopathologic examination of the biopsy specimen revealed ductal structures surrounded by plasmacytoid mioepithelial cells within a myxoid stroma, the final diagnosis corresponded to Pleomorphic Adenoma. Early detection and excision of this lesion in children are important to minimize potential recurrences or malignant transformation.
El adenoma pleomorfo es la neoplasia benigna más común de las glándulas salivales. Su localización común está en glándula parótida, sin embargo, un bajo porcentaje de estos tumores puede ocurrir en glándulas menores. La epidemiología de este tumor muestra que los adultos son los más afectados, con rara ocurrencia en niños o adolescentes. Presentamos el caso de un adenoma pleomorfo localizado en el paladar de un niño de 10 años. La biopsia excisional de la lesión seguida de examen histopatológico de la muestra de biopsia reveló estructuras ductales rodeadas por células mioepiteliales plasmocitóides dentro de un estroma mixoide, siendo el diagnóstico final adenoma pleomorfo. La detección temprana y la excisión de esta lesión en los niños es importante para minimizar las recidivas potenciales o la transformación maligna.
Subject(s)
Humans , Male , Child , Salivary Glands, Minor/pathology , Salivary Gland Neoplasms/diagnosis , Palatal Neoplasms/diagnosis , Adenoma, Pleomorphic/diagnosis , Periosteum/pathology , Tomography, X-Ray Computed , Palate, Hard/pathology , Mouth Mucosa/pathologyABSTRACT
El adenoma pleomorfo es el tumor benigno más frecuente de lasglándulas salivales. Su localización principalmente es en la glándula parótida, pero cuando aparece en una glándula salival menor, el paladar es su localización más común. Presenta un crecimiento lento y continuo; clínicamente se presenta como un nódulo o tumor asintomático, firme y bien delimitado. El diagnóstico se realiza mediante biopsia por aspiración con aguja fi na o biopsia escisional de la lesión, siendo de gran importancia debido a que a pesar de ser una tumoración benigna, en ocasiones puede presentar transformación maligna. El tratamiento consiste en la exéresis completa de la lesión con márgenes sanos. Se presenta el caso de un paciente masculino de 40 años, con una masa en el paladar duro y blando de seis años de evolución. Tras la exéresiscompleta de la lesión, el estudio histopatológico confirmó el diagnósticode adenoma pleomorfo
Pleomorphic adenomas are the most common benign tumor of the minor salivary glands. They are primarily found in the parotid gland, except when they appear in a minor salivary gland, in which case the palate is the most common site. They display a slow, steady growth. Clinically the adenoma appears as a fi rm, well-defi ned, asymptomatic nodule or tumor. Diagnosis is confi rmed by means of fi ne-needle aspiration biopsy or excisional biopsy of the lesion. It is extremely important that they are tested given that, despite their being a benign tumor, they can sometimes become malignant. Treatment consists of the complete excision of the lesion with clean surgical margins. We report the case of a 40-year-old male patient with a mass in the hard and soft palate that had evolved over a period of six years. Following the complete excision of the le-sion, histopathology confi rmed the diagnosis of pleomorphic adenoma.
Subject(s)
Humans , Male , Adult , Adenoma, Pleomorphic/surgery , Adenoma, Pleomorphic/diagnosis , Palatal Neoplasms/surgery , Palatal Neoplasms/diagnosis , Age and Sex Distribution , Adenoma, Pleomorphic/epidemiology , Biopsy, Needle/methods , Histological Techniques , Postoperative Care , Oral Surgical Procedures/methodsABSTRACT
Pleomorphic adenoma (PA) is the most common neoplasm encountered in major and minor salivary glands. Intraorally, it is most frequently developed in the palatal glands. Histologically, it is characterized by a diverse architecture comprised of epithelial stromal elements mixed with mucoid, myxoid, or chondroid fibrohyaline. A PA does not generally present gender bias and can occur at any age with the same clinical behavior. It is usually a round, slow-growing, painless tumor, which is firm upon palpation. We reported two cases of adult patients who were treated using transoral resection at San Juan de Dios Hospital in La Serena.
El Adenoma Pleomorfo es la neoplasia más común de las glándulas salivales mayores y menores. Intraoralmente las glándulas del paladar son las más afectadas. Histológicamente se caracteriza por una arquitectura variada que comprende elementos epiteliales mezclados con estroma mucoide, mixoide, fibrohialino o condroide, Los AP no suelen presentar predisposición por sexos, pudiendo aparecer a cualquier edad, con el mismo comportamiento clínico. Se presentan habitualmente como una tumoración redondeada de crecimiento lento, indolora y firme a la palpación. Presentamos dos casos de pacientes adultos, quienes fueron tratados mediante resección transoral en el hospital de la Serena.
Subject(s)
Humans , Adult , Female , Aged , Adenoma, Pleomorphic/surgery , Adenoma, Pleomorphic/diagnosis , Palatal Neoplasms/surgery , Palatal Neoplasms/diagnosis , Salivary Gland Neoplasms/surgery , Salivary Gland Neoplasms/diagnosis , Palate, Hard/pathology , Tomography, X-Ray ComputedABSTRACT
The pleomorphic adenoma is the most common salivary gland tumor. A remarkable morphological diversity can exist from one tumor to the next. We present here a case of pleomorphic adenoma of minor salivary glands of the soft palate which had predominantly myoepithelial cells with minimal stroma, ductal cells, or tubular elements.
Subject(s)
Adenoma, Pleomorphic/diagnosis , Adult , Biopsy, Needle/methods , Diagnosis, Differential , Humans , Male , Oral Ulcer/diagnosis , Palatal Neoplasms/diagnosis , Palate, Soft/pathology , Salivary Gland Neoplasms/diagnosis , Salivary Glands, Minor/pathologySubject(s)
Adenocarcinoma/diagnosis , Adenocarcinoma/pathology , Adenocarcinoma/physiopathology , Adenocarcinoma/surgery , Biopsy , Diagnosis, Differential , Humans , Laryngeal Mucosa/pathology , Magnetic Resonance Imaging , Male , Middle Aged , Neoplasm Grading , Otorhinolaryngologic Surgical Procedures , Palatal Neoplasms/diagnosis , Palatal Neoplasms/pathology , Palatal Neoplasms/physiopathology , Palatal Neoplasms/surgery , Palatal Obturators , Recovery of Function , Tomography, X-Ray ComputedABSTRACT
Adenoid cystic carcinoma, an uncommon malignant salivary gland neoplasm, is known for its long clinical course, indolent growth, local recurrence and late distant metastasis. We report an unusual case of adenoid cystic carcinoma of the palate in a 64-year-old woman, undiagnosed for more than 15 years, who presented as malignant pleural effusion.
Subject(s)
Carcinoma, Adenoid Cystic/diagnosis , Carcinoma, Adenoid Cystic/pathology , Carcinoma, Adenoid Cystic/secondary , Female , Humans , Middle Aged , Palatal Neoplasms/diagnosis , Palatal Neoplasms/pathology , Pleural Effusion, Malignant/etiology , Pleural Neoplasms/pathology , Pleural Neoplasms/diagnostic imaging , Pleural Neoplasms/secondaryABSTRACT
A malignant myoepithelioma is one of the rarest salivary gland neoplasms which may either arise de novo or develop within a preexisting pleomorphic adenoma or benign myoepithelioma. The parotid gland is the most common primary site and the palate the most common intra-oral site of occurrence. Herein is present a case of a malignant myoepithelioma arising in the hard palate of a 79-year-old woman. The lesion had been examined by biopsy at another hospital, and diagnosed as a poorly differentiated squamous cell carcinoma. The patient underwent a wide local tumor resection. Examination of the resection specimen showed the characteristic histopathological and immunohistochemical features of a malignant myoepithelioma. Five months after the operation, the patient was well without evidence of recurrence or metastasis.
Subject(s)
Aged , Female , Humans , Immunohistochemistry , Myoepithelioma/diagnosis , Palatal Neoplasms/diagnosis , Palate/pathologyABSTRACT
We describe the enhancement patterns of myoepithelioma in two patients with a soft palate mass. In the first case, helical CT revealed a faintly enhancing mass. Histologically, the tumor was composed of plasmacytoid cells in a background of rich myxoid stroma. Immunostaining for CD34 showed scanty blood vessels. In the second case, helical CT revealed an intensely enhancing mass. Histologically, the mass was a cellular tumor with fibrous stroma. Immunostaining for CD34 also showed frequent blood vessels.
Subject(s)
Aged , Female , Humans , Male , Middle Aged , Contrast Media/administration & dosage , Diagnosis, Differential , Iohexol/analogs & derivatives , Myoepithelioma/diagnosis , Palatal Neoplasms/diagnosis , Palate, Soft/diagnostic imaging , Radiographic Image Enhancement/methods , Rare Diseases , Tomography, Spiral Computed/methodsABSTRACT
Salivary duct carcinoma is a rare high-grade neoplasm that more frequently affects the parotid gland. Though neoplasms of this type are infrequent in minor salivary glands, they are less aggressive and may lead to early diagnosis before distant metastases could occur. Salivary duct carcinoma is also the most frequent epithelial component of carcinosarcoma. The present article reports a case of SDC of the palate in a 26-year-old male and discusses SDC as a malignant epithelial component in carcinosarcoma.
Subject(s)
Adenoma/diagnosis , Adult , Carcinoma/diagnosis , Diagnosis, Differential , Follow-Up Studies , Humans , Male , Palatal Neoplasms/diagnosis , Salivary Ducts/pathology , Salivary Gland Neoplasms/diagnosisABSTRACT
Melanoma is a malignant tumor of melanocytes or their precursor cells. It is the third most common skin cancer and is one of the most biologically unpredictable neoplasms. Sunlight is an important etiological factor in cutaneous melanoma. Oral melanoma is relatively uncommon, exhibiting a definite predilection for palate and maxillary gingiva, and is twice as common in males as in females. We herewith report three cases of oral melanoma out of which two occurred on the palate and one in the maxillary gingiva. Their clinical presentations, histopathology and management are discussed.
Subject(s)
Adult , Connective Tissue/pathology , Epithelium/pathology , Female , Gingival Neoplasms/diagnosis , Humans , Male , Melanins , Melanocytes/pathology , Melanoma/diagnosis , Middle Aged , Palatal Neoplasms/diagnosisABSTRACT
Myoepitheliomas of intraoral minor salivary glands are rare and are usually of plasmacytoid type. Myoepitheliomas are considered difficult to diagnose without the aid of ultrastructural and histochemical studies. Here we present a case report of plasmacytoid type of myoepithelioma of palate that was diagnosed by light microscopic examination alone. Considering the non-specificity of ultrastructural and histochemical findings, it is important to pay attention to typical features of plasmacytoid myoepitheliomas to arrive at a diagnosis.
Subject(s)
Adult , Humans , Male , Myoepithelioma/diagnosis , Palatal Neoplasms/diagnosis , Plasma Cells/pathologyABSTRACT
Leiomyomas are rare tumors of the palate amongst which angiomyomas are the commonest sub-type. Recurrence is rare and prognosis is excellent. Only a few case reports are available in literature. We report a case of angiomyoma of the palate presenting as an encapsulated swelling in the roof of the mouth.
Subject(s)
Adult , Angiomyoma/diagnosis , Humans , Male , Palatal Neoplasms/diagnosisSubject(s)
Adult , Female , Humans , Lymphoma, Non-Hodgkin/diagnosis , Palatal Neoplasms/diagnosis , Palate/pathologyABSTRACT
Presentación de caso clínico de un paciente de sexo femenino, edad 65 años, raza negra; por lesión ubicada en la bóveda palatina de aspecto verrugoso, tipo coliflor, ulcerada, cubierta por una capa blanquecina, sumamente dolorosa, sangrante espontáneamente y sensación "urente" (quemadura). En este caso, lo importante es que la paciente refiere ser fumadora con la candela invertida, "fumar con la candela pa' dentro", desde hace más de treinta años. Esta paciente fue sometida a tratamiento quirúrgico, siendo su diagnóstico definitivo (carcinoma espinocelular de paladar), que por ser una de las características más importantes como fumar con el cigarrillo invertido, merece ser reportado. Asimismo se realizó una revisión bibliográfica de esta entidad patológica y sus características clínicas, tratamiento y pronóstico)
Subject(s)
Humans , Female , Aged , Carcinoma, Squamous Cell/therapy , Palatal Neoplasms/diagnosisSubject(s)
Adolescent , Adult , Humans , Female , Granulosa Cell Tumor/diagnosis , Palatal Neoplasms/diagnosis , Tongue Neoplasms/diagnosis , BiopsyABSTRACT
A case of Kaposi's sarcoma of the palate in a patient who is imunosuppressed following renal transplant is reported
Subject(s)
Humans , Male , Palatal Neoplasms/diagnosis , Kidney Transplantation/adverse effects , Immunosuppression TherapyABSTRACT
Se revisan 62 casos de tumores de Glándulas Salivales accesorias de cavidal oral encontrando que estas neoplasías son más frecuentes en el sexo femenino con una relación 3:2. El 71% de los tumores fueron malignos, siendo el más frecuente el carcinoma mucoepidermoide. De los tumores benignos el más frecuente fué el tumor mixto. El sitio anatómico más frecuentemente afectado fué el paladar