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2.
Rev. otorrinolaringol. cir. cabeza cuello ; 79(4): 437-441, dic. 2019. graf
Article in Spanish | LILACS | ID: biblio-1058720

ABSTRACT

RESUMEN El melanoma mucoso maligno es un tumor neuroectodérmico de menos del 5% de las neoplasias nasosinusales. Es un tumor de mal pronóstico clásicamente su promedio de supervivencia a cinco años es cercano al 28% y 17,5% a diez años, siendo aún peor cuando existe metástasis en cuello. Se presentan a continuación dos casos de melanoma mucoso en cavidad nasal y senos paranasales, el primero mujer 58 años con melanoma septal llevada a septotomía abierta más quimioterapia y radioterapia adyuvante, con recurrencia en cuello submaxilar derecho tratada con vaciamiento supraomohioideo actualmente sin recurrencia; el segundo hombre de 40 años con antecedente de resección melanoma septal quien presenta nuevo melanoma región etmoidal izquierda luego de su primera cirugía y es llevado a resección endoscópica transnasal sin tratamiento adyuvante por decisión del paciente.


ABSTRACT Sinonasal mucosal melanoma is a neuroectodermic tumor account less 5% of nasosinusal tumors. It has a poor prognosis with a five-year average survival near 28% and 17.5% to 10 years; if neck metastasis is even worst. Here we present two clinical cases. First one a woman 58 years old with septal melanoma who receives an open septectomy with chemotherapy and radiotherapy with submaxillary recurrence treated with supraomohyoid neck dissection. The second case, a man 40 years old with previous septal melanoma surgery who has an ethmoid sinus recurrence and receives transnasal endoscopic surgery without adjuvant therapy by patient desire.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Melanoma/pathology , Nasal Mucosa/pathology , Paranasal Sinus Neoplasms/pathology , Paranasal Sinus Neoplasms/therapy , Nasal Obstruction/etiology , Nose Neoplasms/pathology , Nose Neoplasms/therapy , Radiotherapy, Adjuvant , Melanoma/therapy , Nasal Mucosa/surgery
3.
Braz. j. otorhinolaryngol. (Impr.) ; 85(6): 698-704, Nov.-Dec. 2019. tab, graf
Article in English | LILACS | ID: biblio-1055503

ABSTRACT

Abstract Introduction: Sinonasal organising haematoma is a recently described, rare, benign inflammatory condition, which closely resembles malignancy in its clinical presentation. Objective: To describe the clinical features of organising haematoma and to review the evolution of surgical options successfully used. Methods: A retrospective review of charts of all patients with a histopathological diagnosis of sinonasal organising haematoma was performed. Results: Six (60%) of the 10 patients were male with a mean age of 47.4 years. All patients had unilateral disease with recurrent epistaxis as the presenting symptom. Maxillary sinus was the most commonly involved sinus. There was no history of trauma in any of the patients. Hypertension (80%) was the most commonly associated comorbidity. Contrast-enhanced CT scan of the paranasal sinuses showed heterogeneous sinus opacification with/without bone erosion. Histopathological examination was diagnostic. Complete endoscopic excision was done in all patients resulting in resolution of the disease. Conclusion: Awareness of this relatively new clinical entity and its evaluation and treatment is important for otolaryngologists, maxillofacial surgeons and pathologists alike. Despite the clinical picture of malignancy, histopathological features of benign disease can safely dispel such a diagnosis.


Resumo Introdução: Hematoma nasossinusal em organização é uma condição inflamatória benigna rara, recentemente descrita, que se assemelha a lesões malignas em sua apresentação clínica. Objetivo: Descrever as características clínicas do hematoma em organização e analisar a evolução das opções cirúrgicas usadas com sucesso. Método: Foi feita a revisão retrospectiva dos prontuários de todos os pacientes com diagnóstico histopatológico de hematoma nasossinusal em organização. Resultados: Seis (60%) dos 10 pacientes eram do sexo masculino, com média de 47,4 anos. Todos os pacientes apresentavam doença unilateral com epistaxe recorrente como sintoma de apresentação. O seio maxilar era o mais comumente afetado. Não havia histórico de trauma em qualquer dos pacientes. Hipertensão (80%) foi a comorbidade mais comumente associada. A tomografia computadorizada dos seios paranasais com contraste mostrou opacificação heterogênea do seio com/sem erosão óssea. O exame histopatológico foi diagnóstico. A excisão endoscópica completa foi feita em todos os pacientes, resultou na resolução da doença. Conclusão: A conscientização a respeito dessa entidade clínica relativamente nova e sua avaliação e tratamento são importantes para os otorrinolaringologistas, cirurgiões buco-maxilo-faciais e patologistas. Apesar do quadro clínico de malignidade, as características histopatológicas da doença benigna podem descartar com segurança esse diagnóstico.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Paranasal Sinus Neoplasms/pathology , Nose Neoplasms/pathology , Hematoma/pathology , Paranasal Sinus Neoplasms/surgery , Paranasal Sinus Neoplasms/diagnostic imaging , Tomography, X-Ray Computed , Nasal Obstruction/diagnostic imaging , Epistaxis/diagnostic imaging , Nose Neoplasms/surgery , Nose Neoplasms/diagnostic imaging , Retrospective Studies , Hematoma/surgery , Hematoma/diagnostic imaging , Maxillary Sinus/surgery
5.
Int. j. morphol ; 35(2): 745-750, June 2017. ilus
Article in Spanish | LILACS | ID: biblio-893049

ABSTRACT

Los osteomas fronto-etmoidales son los tumores benignos más frecuentes de los senos paranasales, pudiendo evolucionar con complicaciones por compresión de estructuras adyacentes. Se presenta el caso de una paciente de 63 años de edad, que consultó por aumento de volumen nasofrontal, cefalea y diplopía. Tras el examen clínico, se evidenció una asimetría facial con lateralización del bulbo ocular derecho y exoftalmo. La tomografía de los senos paranasales mostró una lesión que ocupa parcialmente el seno frontal, etmoidal y parte de la cavidad nasal. Los cuidados anatómicos y planificación quirúrgica se desarrollaron en un modelo estereolitográfico mientras que la cirugía de exéresis total se realizó con ayuda del sistema piezoeléctrico. El examen histológico confirmó el diagnostico de osteoma. Se obtuvo una reconstrucción exitosa, recuperando totalmente simetría y función ocular.


Fronto-ethmoidal osteomas are the most frequent benign tumors of the paranasal sinuses, and may evolve with complications by compression of adjacent structures. The case is a 63-year-old female patient, who consulted about increased nasofrontal volume, headache and diplopia. After the clinical exam, she presented a facial asymmetry with lateralization of the right eyeball and exophthalmus. Computed tomography of the sinuses showed a lesion that partially occupies the frontal sinus, ethmoidal sinus and part of the nasal cavity. The anatomical care and surgical planning was developed in a stereolithographic model while the total excision surgery was performed with the help of the piezoelectric system. Histological examination confirmed the diagnosis of osteoma. A successful reconstruction is obtained, fully recovering symmetry and ocular function.


Subject(s)
Humans , Female , Middle Aged , Ethmoid Bone/surgery , Frontal Sinus/surgery , Osteoma/surgery , Paranasal Sinus Neoplasms/surgery , Piezosurgery/methods , Surgery, Computer-Assisted , Ethmoid Bone/pathology , Frontal Sinus/pathology , Models, Anatomic , Osteoma/pathology , Paranasal Sinus Neoplasms/pathology , Patient Care Planning
6.
Rev. AMRIGS ; 61(1): 64-67, jan.-mar. 2017. ilus
Article in Portuguese | LILACS | ID: biblio-849262

ABSTRACT

Introdução: O Schwannoma é uma neoplasia benigna com origem nas células de Schwann presentes na bainha de nervos autossômicos periféricos. Localiza-se cranial ou extracranial. Na cabeça e pescoço constitui 30 a 45% dos casos extracraniais, sendo que 4% deles estão localizados no nariz e seios paranasais. Relato do caso: Paciente feminina, 37 anos, realizou tomografia de crânio após queda para investigar trauma cranioencefálico. Esta identificou velamento de seios paranasais à esquerda. O achado motivou a investigação da hiposmia e obstrução nasal à esquerda de longa data. À rinoscopia anterior, observou-se lesão expansiva polipoide ocupando a fossa nasal, não permitindo a passagem do nasofibroscópio. Tomografia computadorizada evidenciou lesão ocupando totalmente a fossa nasal esquerda, velamento do seio maxilar e células etmoidais anteriores e posteriores à esquerda. Realizou-se exérese endoscópica da lesão, que tinha provável origem no recesso esfenoetmoidal. A biópsia transoperatória com congelação observou lesão inflamatória. A confirmação do diagnóstico de Schwannoma foi feita pelo anatomopatológico e imuno-histoquímica, que evidenciou alta reatividade à proteína S-100. Discussão: As lesões intranasais unilaterais apresentam inúmeras possibilidades diagnósticas. Os sintomas são inespecíficos e os exames de imagem pouco esclarecedores. Neste relato, a tomografia sugeriu pólipo de Killian ou papiloma invertido pela unilateralidade da lesão. Porém, as características histopatológicas e a imunorreatividade à proteína S-100 auxiliaram na confirmação diagnóstica. Conclusão: O Schwannoma intranasal faz parte do diagnóstico diferencial das lesões intranasais. O exame histopatológico e a imunohistoquímica são de extrema importância para confirmação diagnóstica frente à inespecificidade dos sintomas e achados radiológicos (AU)


Introduction: Schwannoma is a benign neoplasm originating in the Schwann cells present in the sheath of peripheral autosomal nerves. It is located cranially or extracranially. In the head and neck it comprises 30 to 45% of extracranial cases, 4% of which located in the nose and paranasal sinuses. Case report: A 37-year-old female patient underwent skull tomography after a fall to investigate cranioencephalic trauma. This identified veiling of paranasal sinuses on the left. The finding motivated the investigation of long-standing hyposmia and nasal obstruction on the left. At anterior rhinoscopy, an expansive polypoid lesion occupying the nasal fossa was observed, not allowing the nasofibroscope to pass. Computed tomography revealed a lesion totally occupying the left nasal fossa, maxillary sinus veil, and anterior and posterior ethmoid cells on the left. Endoscopic excision of the lesion that was likely to originate in the sphenoethmoidal recess was performed. Intraoperative biopsy with freezing showed an inflammatory lesion. Confirmation of the Schwannoma diagnosis was made by pathology and immunohistochemistry that showed high reactivity to S-100 protein. Discussion: Unilateral intranasal lesions present numerous diagnostic possibilities. The symptoms are nonspecific and imaging exams are not very elucidating. In this report, CT scan suggested a Killian polyp or inverted papilloma due to the unilaterality of the lesion. However, the histopathological characteristics and immunoreactivity to the S-100 protein aided in the diagnostic confirmation. Conclusion: Intranasal Schwannoma is part of the differential diagnosis of intranasal lesions. Histopathological examination and immunohistochemistry are extremely important for diagnostic confirmation in the face of the non-specificity of symptoms and radiological findings (AU)


Subject(s)
Humans , Female , Adult , Neurilemmoma/diagnosis , Nose Neoplasms/diagnosis , Paranasal Sinus Neoplasms/diagnosis , Nasal Cavity/pathology , Neurilemmoma/pathology , Neurilemmoma/surgery , Nose Neoplasms/pathology , Nose Neoplasms/surgery , Paranasal Sinus Neoplasms/pathology , Paranasal Sinus Neoplasms/surgery , Paranasal Sinuses/pathology
7.
Article in Spanish | LILACS | ID: biblio-908138

ABSTRACT

El pseudotumor inflamatorio (PTI) es una entidad no neoplásica, de etiología desconocida, caracterizada por la proliferación de un infiltrado inflamatorio policlonal sobre un estroma de tejido conjuntivo. Pueden ser definidos como lesiones que clínica y radiológicamente simulan neoplasias. El pseudotumor inflamatorio puede causar dolor facial, obstrucción nasal, exoftalmos y discapacidad visual y con frecuencia causa la erosión y destrucción ósea. Los corticoesteroides, la radioterapia y la cirugía se han utilizado como modalidades de tratamiento, solos o en combinación.


The inflammatory pseudotumour (IPT) is a nonneoplastic entity of unknown origin, and is characterised by a proliferation of connective tissue and a polyclonal inflammatory infiltrate. May be defined as lesions that clinically and radiologically simulate neoplasms. Inflammatory pseudotumour sometimes causes facial pain, nasal obstruction, exophthalmos and visual impairment, and often causes bone erosion and destruction. Corticosteroids, radiotherapy and surgery have been used as treatment modalities either on their own or in combination.


O pseudo-tumor inflamatório (PTI) é uma entidade não neoplásica de etiologia desconhecida, caracterizada pela proliferação de um infiltrado inflamatório policlonal em um estroma do tecido conjuntivo. Podem ser definidos como lesões que simulam neoplasias clínica e radiologicamente. O pseudo-tumor Inflamatório pode causar dor facial, obstrução nasal, exoftalmia (olhos saltados), deficiência visual e freqüentemente provoca o desgaste e a destruição óssea. Os cortiçoesteroides, a radioterapia e a cirurgia têm sido usadas como modalidades de tratamento, por si só ou em combinação.


Subject(s)
Male , Humans , Middle Aged , Granuloma, Plasma Cell/diagnosis , Granuloma, Plasma Cell/surgery , Epistaxis/therapy , Natural Orifice Endoscopic Surgery , Paranasal Sinus Neoplasms/diagnosis , Paranasal Sinus Neoplasms/pathology , Paranasal Sinus Neoplasms/surgery
8.
Rev. chil. radiol ; 22(4): 164-170, 2016. ilus
Article in Spanish | LILACS | ID: biblio-844623

ABSTRACT

Abstract: Dural metastases are an unusual form of spread in treated sinonasal malignancies. An analysis is presented of 20 cases of dural metastases diagnosed during imaging follow-up in a selection of cases in which anterior craniofacial resection was performed. They included 12 undifferentiated sinonasal carcinomas, 7 olfactory neuroblastomas, and 1 adenoid cystic carcinoma case. Dural metastases appeared on an average of 7.3 years after treatment in olfactory neuroblastoma. The maximum distance from malignancy to dural metastases was 14 cm for olfactory neuroblastoma, and 4.3 cm for undifferentiated sinonasal carcinoma. Dural metastases in the Burr holes were observed in 50% of undifferentiated sinonasal carcinoma, and 29% of olfactory neuroblastomas. Dural metastases presented as a nodular (60%), multinodular (10%), cystic (15%), and plaque (15%) pattern. These are suggestive of a local venous spread mechanism related to tumour rupture during surgery of anterior cranial fossa. Long-term follow-up with cranial inclusion would be indicated, given the possible late and distant presentation of dural metastases.


Resumen: Presentamos las metástasis durales como forma inusual de diseminación de tumores nasosinusales malignos tratados; se revisan 20 casos diagnosticados durante el seguimiento imagenológico a un grupo tratado con resección craneofacial anterior. Evaluamos metástasis durales en 12 carcinomas nasosinusales indiferenciados, 7 neuroblastomas olfatorios y un carcinoma adenoquístico. En neuroblastomas olfatorios aparecieron metástasis durales en promedio 7,3 años postratamiento. La distancia máxima del tumor a la metástasis fue de 14 cm para neuroblastoma olfatorio y de 4,3 cm para carcinoma nasosinusal indiferenciado. Observamos metástasis durales en los agujeros de trepanación en el 50% de los carcinomas nasosinusales indiferenciados y en el 29% de los neuroblastomas olfatorios. Las metástasis durales presentaron patrón nodular (60%), multinodular (10%), quístico (15%) y en placa (15%). Proponemos un mecanismo venoso local de diseminación relacionado a disrupción tumoral o quirúrgica de la fosa craneal anterior. El seguimiento a largo plazo con inclusión craneal estaría indicado por la posible presentación tardía y distante de metástasis durales.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Dura Mater/pathology , Meningeal Neoplasms/diagnostic imaging , Meningeal Neoplasms/secondary , Paranasal Sinus Neoplasms/pathology , Head and Neck Neoplasms/pathology , Retrospective Studies
10.
Rev. otorrinolaringol. cir. cabeza cuello ; 75(2): 167-172, ago. 2015. ilus
Article in Spanish | LILACS | ID: lil-757900

ABSTRACT

El melanoma mucoso se considera un subtipo distinto al cutáneo. El 40% a 50% de los melanomas mucosos están localizados en la cabeza y el cuello, siendo los más frecuentes los nasosinusales y los de cavidad oral; en la porción anterior del tabique nasal y los cornetes inferior y medio. Estas neoplasias se originan de los melanocitos de la mucosa y submucosa nasosinusal. Generalmente se diagnostican tardíamente, frecuentemente con metástasis a distancia. Ante clínica nasosinusal unilateral sospechosa es muy importante una exploración exhaustiva de las vías aerodigestivas superiores y posteriormente, un estudio anatomopatológico. Se presenta a una paciente de 56 años, con historia de epistaxis de repetición de meses de evolución. En la exploración presenta una tumoración polipoidea que ocupa toda la fosa nasal derecha, con desviación septal y deformidad de la pirámide nasal. El estudio anatomopatológico informa de melanoma maligno infiltrante. Durante la hospitalización, la paciente presenta dificultad para caminar y dolor en cadera derecha, siendo diagnosticada por traumatología de fractura basicervical. Durante la cirugía, se envía fragmento óseo de cadera para estudio anatomopatológico, compatible con lesión de sustrato tisular óseo metastatizado por una proliferación celular de morfología e inmunofenotipo de melanoma.


The mucosal melanoma is considered a distinct subtype of cutaneous melanoma. The 40%-50% of cases of mucosal melanomas is located in the head and neck, the most common are found in sinonasal level and in the oral cavity; In the anterior portion of the nasal septum and the inferior and middle turbinates. Those neoplasms originate from the malignant cells found in the mucosa and submucosa. Usually are lately diagnosed, with distant metastases. If suspicious unilateral sinonasal manifestations appears is extremely important to realize an exhaustive exploration of superior aerodigestive vias and a histopathological examination of the lesion. We present a 56 year old with repeated epistaxis of several months of duration. The examination revealed a polypoid tumor occupying the entire right nostril, septal deviation and deformity of the nasal pyramid. Pathological studies reports infiltrating malignant melanoma. During the hospitalization the patient has difficulty walking and pain in the right hip, being diagnosed by Traumatology of fracture basicervical. During the surgery, a bone fragment hip is sent for anathomopathology study which is reported as bone tissue injury support substrate metastasized malignant cell proliferation by immunophenotype and morphology of melanoma.


Subject(s)
Humans , Female , Middle Aged , Melanoma/diagnosis , Melanoma/pathology , Paranasal Sinus Neoplasms/diagnosis , Paranasal Sinus Neoplasms/pathology , Epistaxis/etiology , Hip Fractures , Magnetic Resonance Imaging , Tomography, X-Ray Computed
11.
Säo Paulo med. j ; 132(6): 377-381, Nov-Dec/2014. tab, graf
Article in English | LILACS | ID: lil-726378

ABSTRACT

CONTEXT: Pituitary macroadenomas are rare intracranial tumors. In a few cases, they may present aggressive behavior and invade the sphenoid sinus and nasal cavity, causing unusual symptoms. In this paper, we report an atypical case of pituitary adenoma presenting as a nasal mass. CASE REPORT: The patient was a 44-year-old woman who had had amenorrhea and galactorrhea for ten months, with associated nasal obstruction, macroglossia and acromegaly. Both growth hormone and prolactin levels were increased. Magnetic resonance imaging showed a large mass originating from the lower surface of the pituitary gland, associated with sella turcica erosion and tumor extension through the sphenoid sinus and nasal cavity. Histopathological analysis demonstrated a chromophobe pituitary adenoma with densely packed rounded epithelial cells, with some atypias and rare mitotic figures. There was no evidence of metastases. CONCLUSION: Macroadenoma invading the nasal cavity is a rare condition and few similar cases have been reported in the literature. This study contributes towards showing that tumor extension to the sphenoid sinus and nasopharynx needs to be considered and investigated in order to make an early diagnosis when atypical symptoms like nasal obstruction are present. .


CONTEXTO: Macroadenomas hipofisários são tumores intracraniais raros. Em alguns casos, podem apresentar comportamento agressivo e invadir o seio esfenoidal e a cavidade nasal, causando sintomas não usuais. Neste relato de caso, descrevemos um caso atípico de adenoma hipofisário manifestando-se como uma massa nasal. RELATO DE CASO: A paciente de 44 anos, do sexo feminino, apresentava amenorreia e galactorreia por 10 meses associando-se a obstrução nasal, macroglossia e acromegalia. Os níveis do hormônio de crescimento e de prolactina apresentaram-se aumentados. Ressonância magnética mostrou uma grande massa originada da superfície inferior da glândula hipofisária associada com erosão da sela túrcica e extensão do tumor através do seio esfenoidal e cavidade nasal. Análise histopatológica demonstrou adenoma hipofisário cromófobo com células epiteliais arrendondadas densamente agrupadas com algumas atipias e escassas figuras de mitose. Não houve evidências de metástase. CONCLUSÃO: O macroadenoma invasivo para a cavidade nasal é uma condição rara e há poucos relatos similares descritos na literatura. Este trabalho contribui para mostrar que, na presença de sintomas atípicos como a obstrução nasal, a extensão para o seio esfenoidal e para a nasofaringe deve ser considerada e investigada para um diagnóstico precoce. .


Subject(s)
Adult , Female , Humans , Adenoma/pathology , Nasal Cavity/pathology , Nose Neoplasms/pathology , Paranasal Sinus Neoplasms/pathology , Pituitary Neoplasms/pathology , Sphenoid Sinus/pathology , Adenoma/surgery , Diagnosis, Differential , Human Growth Hormone/blood , Insulin-Like Growth Factor I/analysis , Magnetic Resonance Imaging , Nasal Cavity/surgery , Nasal Obstruction/etiology , Neoplasm Invasiveness/pathology , Nose Neoplasms/surgery , Paranasal Sinus Neoplasms/surgery , Pituitary Neoplasms/surgery , Sphenoid Sinus/surgery
12.
Rev. otorrinolaringol. cir. cabeza cuello ; 73(2): 146-150, ago. 2013. graf, tab
Article in Spanish | LILACS | ID: lil-690559

ABSTRACT

Introducción: El papiloma invertido es un tumor benigno inusual del tracto nasosinusal, caracterizado por el riesgo de recurrencia y transformación maligna. Objetivo: Nuestro objetivo es describir la serie de casos diagnosticados con papiloma invertido del tracto nasosinusal entre 2002 y 2010. Material y método: Se trata de un análisis retrospectivo de los casos nuevos de papiloma invertido del tracto nasosinusal atendidos en nuestro Hospital entre los años 2002 y 2010. Resultados: Se presentaron 25 casos nuevos de papiloma invertido. Los síntomas tenían en promedio 2 años de evolución, siendo la obstrucción nasal y rinorrea los más frecuentes. La etapificación preoperatoria fue realizada mediante tomografía computarizada en 15 pacientes. El abordaje endoscópico fue el preferido. Cincuenta y seis por ciento de los pacientes correspondía a la etapa 2 de la clasificación de Krause. El promedio de seguimiento fue 29 meses. Durante ese periodo, 4 casos presentaron recurrencia, correspondiendo al 16% de nuestra serie. La mitad de ellos presentó displasia o atipia al momento de la recurrencia. Ocurrió 1 caso de transformación maligna, el cual se presentó como un carcinoma indiferenciado. Conclusión: Las características generales son similares a los reportes internacionales. En nuestro medio los pacientes son diagnosticados en etapas avanzadas de la enfermedad, no obstante, el abordaje endoscópico es el método quirúrgico preferido.


Introduction: Inverted papilloma is an unusual benign tumor of the sinonasal tract, characterized by an important risk of recurrence and malignant transformation. Aim: Our objective is to describe the case series diagnosed with inverted papilloma of the sinonasal tract between the years 2002 and 2010. Material and method: A retrospective analysis of new cases of inverted papilloma of the sinonasal tract treated at our Hospital between the years 2002 and 2010. Results: 25 cases of newly diagnosed inverted papilloma presented in our institution. The symptoms had on average 2 years of evolution, being nasal obstruction and rhinorrhea the most frequent. Preoperative staging by computed tomography (CT) was performed in 15 patients. The endoscopic aproach was preferred as surgical approach. 56% of the patients corresponded to stage 2 of Krause classification. Median folow up was 29 months. During that period, 4 patients had recurrence, corresponding to 16% in our series. Half of these patients had dysplasia or atypia at the time of recurrence. 1 case of malignant transformation ocurred, which presented as an undifferentiated carcinoma. Conclusions: General characteristics were similar to those reported in international reports. In our setting, patients are diagnosed in advanced stages of disease, nevertheless, endoscopic approach is the preferred surgery method.


Subject(s)
Humans , Male , Female , Middle Aged , Paranasal Sinus Neoplasms/surgery , Papilloma, Inverted/surgery , Recurrence , Paranasal Sinus Neoplasms/pathology , Tomography, X-Ray Computed , Nasal Obstruction/etiology , Retrospective Studies , Follow-Up Studies , Papilloma, Inverted/pathology , Endoscopy/methods , Neoplasm Staging
13.
Braz. j. otorhinolaryngol. (Impr.) ; 79(1): 13-17, jan.-fev. 2013. tab
Article in Portuguese | LILACS | ID: lil-667969

ABSTRACT

O papiloma invertido (PI) apresenta diversos tipos de tratamento cirúrgico. A abordagem endoscópica exclusiva tem se mostrado na última década como boa opção em relação à abordagem externa. OBJETIVO: Descrever a amostra dos pacientes com diagnóstico de papiloma invertido, mostrar a experiência do serviço no manejo do tumor e comparar os dados com os da literatura. Forma do Estudo: Estudo de coorte histórica com corte transversal. MÉTODO: Estudo retrospectivo dos prontuários de 17 pacientes operados em um serviço de Rinologia entre 2005 e 2011. Foram avaliados perfil epidemiológico, estadiamento de Krouse, via de acesso cirúrgico, malignização e recorrência pós-operatória e a correlação entre recidivas e estadiamento pré-operatório, via de acesso cirúrgico e malignização. RESULTADOS: Cinco (29,41%) dos pacientes foram classificados como estádio T2 de Krouse, nove (52,94%) como T3 e três (17,65%) como T4. Três (17,65%) pacientes apresentaram malignização e quatro (23,5%) recidiva. Onze pacientes (64,70%) foram submetidos à via endoscópica exclusiva, três (17,6%)à via combinada e três (17,6%) à via aberta. CONCLUSÃO: O acesso endoscópico exclusivo atualmente é um método não só eficaz como também seguro para o tratamento dos estádios mais avançados do PI.


Inverted papilloma (IP) has several treatment avenues. The endoscopic approach in the last decade has proven to be a good option over the traditional approach. OBJECTIVE: Describe the epidemiological profile of patients with inverted Papilloma, describe our experience on managing this tumor and compare our data with the literature. Study Design: Cross-sectional, historical cohort. METHOD: Retrospective study of medical records of 17 patients treated for histopathologicallyconfirmed inverted papilloma between 2005 and 2011. We assessed patients age, gender, tumor side, symptoms, diagnosis, comorbidities and habits, Krouse staging, surgical approach, intraoperative and postoperative, and malignant postoperative recurrence and also the correlation between recurrence with preoperative staging, the surgical approach used, and the presence of malignancy. RESULTS: Five (29.41%) patients were classified as Krouse stage T2, 9 (52.94%) as T3 and 3 (17.65%) as T4. Three (17.65%) patients had malignancy and the recurrence rate was 23.5% (4 pacients). Eleven patients (64.70%) underwent endoscopic approach, 3 (17.6%) the combined aprroach (endoscopic assisted) and 3 (17.6%) external approach. CONCLUSION: The endoscopic approach is currently becoming a method not only effective but also safe for the treatment of more advanced stages of IP.


Subject(s)
Aged , Female , Humans , Male , Middle Aged , Papilloma, Inverted/surgery , Paranasal Sinus Neoplasms/surgery , Cohort Studies , Cross-Sectional Studies , Endoscopy/methods , Neoplasm Staging , Papilloma, Inverted/pathology , Paranasal Sinus Neoplasms/pathology , Retrospective Studies , Treatment Outcome
15.
Int. j. odontostomatol. (Print) ; 6(3): 296-301, 2012. ilus
Article in English | LILACS | ID: lil-676189

ABSTRACT

We present the case of a patient, a 59 year-old man, with Sinonasal Adenoid Cystic Carcinoma. Magnetic resonance exam revealed invasion of the right orbit and brain at the level of the anterior cranial fossa floor. Due to the large volume, we decided to perform radio-chemotherapy treatment to diminish the size of the lesion. On conclusion of the first stage of treatment, reduction in tumor size was confirmed by computerized tomography exam and we decided to perform surgical resection with right ocular globe preservation. At present the patient is under periodic control and without major complications...


Se presenta el caso de un paciente de sexo masculino de 59 años con carcinoma adenoide quístico nasosinusal. El examen de resonancia magnética reveló la invasión de la órbita derecha y el cerebro a nivel del suelo de la fosa craneal anterior. Debido al gran volumen, se decidió realizar el tratamiento de radio-quimioterapia para disminuir el tamaño de la lesión. Al término de la primera etapa del tratamiento, la reducción del tamaño del tumor fue confirmada por el examen de tomografía computarizada y se decidió realizar una resección quirúrgica con preservación del globo ocular derecho. En la actualidad el paciente se encuentra bajo el control periódico y sin mayores complicaciones...


Subject(s)
Humans , Male , Middle Aged , Carcinoma, Adenoid Cystic/surgery , Carcinoma, Adenoid Cystic/diagnosis , Paranasal Sinus Neoplasms/surgery , Paranasal Sinus Neoplasms/diagnosis , Carcinoma, Adenoid Cystic/pathology , Magnetic Resonance Imaging , Paranasal Sinus Neoplasms/pathology , Tomography, X-Ray Computed
16.
An. bras. dermatol ; 86(4): 779-783, jul.-ago. 2011. ilus
Article in Portuguese | LILACS | ID: lil-600625

ABSTRACT

O papiloma invertido schneideriano é uma neoplasia de origem no epitélio de revestimento que surge da mucosa respiratória revestindo a cavidade nasal e os seios paranasais. Frequentemente, surge como uma lesão unilateral no septo nasal e estende-se secundariamente para o nariz e os seios paranasais. Este trabalho relata um caso incomum desta patologia, com o envolvimento da cavidade oral em um homem branco, de 61 anos de idade, cuja avaliação clínica revelou uma massa vegetante no rebordo alveolar direito da maxila, com duração de aproximadamente 4 meses. Após avaliação radiográfica, constatouse o envolvimento do seio maxilar. A análise microscópica, hibridização in situ e análise imunoistoquímica da peça cirúrgica levaram a um diagnóstico de displasia moderada em PIS associado à infecção por HPV.


Inverted Schneiderian papilloma (ISP) is a neoplasm of epithelial lining origin which arises in the respiratory mucosa that lines the nasal cavity and paranasal sinuses. The inverted Schneiderian papilloma frequently appears as a unilateral lesion in the nasal septum and extends secondarily to the nasal and paranasal sinuses. This paper reports an unusual case of this pathology with involvement of the oral cavity in a 61-year-old white man. Clinical evaluation revealed a vegetating mass in the alveolar ridge of the right maxilla that had been present for approximately 4 months. After radiographic evaluation, involvement of the maxillary sinus was detected. Microscopic evaluation, in situ hybridization and immunohistochemical analysis of the specimen led to a diagnosis of ISP moderate dysplasia associated with HPV infection.


Subject(s)
Humans , Male , Middle Aged , Mouth Neoplasms/pathology , Papilloma, Inverted/pathology , Papillomavirus Infections/complications , Paranasal Sinus Neoplasms/pathology , Immunohistochemistry , In Situ Hybridization , Mouth Neoplasms/diagnosis , Mouth Neoplasms/virology , Neoplasm Invasiveness , Papilloma, Inverted/diagnosis , Papilloma, Inverted/virology , Papillomavirus Infections/diagnosis , Paranasal Sinus Neoplasms/diagnosis , Paranasal Sinus Neoplasms/virology
17.
JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 2011; 21 (5): 309-310
in English | IMEMR | ID: emr-131109

ABSTRACT

Meningiomas are commonly encountered as intracranial brain tumours, but extracranial meningiomas do occur although seen rarely. Here we present a case of extracranial meningioma presenting as a mass over the medial canthus of left eye and the glabella with extension into the left ethmoid sinuses, without any neurological symptoms or signs. The patients underwent surgical excision, plastic surgical reconstruction and adjuvant radiotherapy after 3-dimensional conformal treatment planning


Subject(s)
Humans , Male , Orbital Neoplasms , Ethmoid Sinus , Meningioma/pathology , Paranasal Sinus Neoplasms/pathology
18.
Pakistan Journal of Otolaryngology-Head and Neck Surgery. 2011; 27 (2): 37-38
in English | IMEMR | ID: emr-118262

ABSTRACT

To analyse the sex and age incidences, clinical presentations and histopathological picture of the benign tumours of nose and paranasal sinuses. Prospective, Longitudinal, Descriptive. GMS Memorial Academy of ENT and HNS,TUTH, Kathmandu, Nepal. 2 years, September 2008 to August 2010. All cases of benign masses of nose and paranasal sinuses who visited the Outpatient department and were undergoing surgical intervention were included. The histological proven malignant masses were excluded from the study. Out of 49 patients, majority of the patients were between 13-20 years [34.69%]. Male:female ratio was 3.9:l.The most common presenting symptoms were unilateral nasal obstruction and nasal bleeding [65.29%]. Inverted papilloma and angiofibroma were the most common tumours [42.84%]. All masses of nose and paranasal sinuses should be subjected to histopathological examination and followed up for two years for assessment of outcome of treatment and monitoring recurrences


Subject(s)
Humans , Adolescent , Young Adult , Male , Female , Paranasal Sinus Neoplasms/pathology , Paranasal Sinus Neoplasms/diagnosis , Nose Neoplasms/diagnosis , Paranasal Sinus Neoplasms/epidemiology , Nose Neoplasms/epidemiology , Prospective Studies
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