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1.
Rev. pediatr. electrón ; 16(3): 28-32, oct. 2019. ilus
Article in Spanish | LILACS (Americas) | ID: biblio-1046286

ABSTRACT

INTRODUCCIÓN La peritonitis meconial (PM) es una peritonitis localizada o generalizada, aséptica, química o de cuerpo extraño; producto del paso de meconio a la cavidad peritoneal y esta correlacionada con la perforación prenatal del tracto digestivo. Se presenta en 1 de cada 30.000 recién nacidos (RN). El diagnostico ecográfico prenatal mejora los resultados perinatales, el hallazgo más frecuente es la ascitis. La PM requiere un tratamiento multidisciplinario urgente, la mayoría es de resolución quirúrgica. OBJETIVO Dar a conocer una patología infrecuente, que requiere un alto grado de sospecha diagnostica para otorgar un manejo perinatal específico y oportuno. Caso clínico Primigesta de 29 años sin antecedentes mórbidos, cursando embarazo controlado de 36+5 semanas. En control ecográfico se evidencia ascitis fetal. Se hospitaliza en alto riesgo obstétrico, descartando patología metabólica e infecciosa. A las 37 semanas por cesárea de urgencia, se obtiene RN con distensión abdominal y hepatomegalia. En laparotomía exploradora se evidencia asas intestinales indemnes. En re intervención se encuentra hernia de íleon distal perforada, se confecciona ostomia, evoluciona favorablemente y es dado de alta. DISCUSIÓN Es fundamental considerar la PM dentro de los diagnósticos diferenciales de ascitis fetal. Un diagnóstico oportuno mejora los resultados perinatales y permite prevenir posibles complicaciones.


INTRODUCTION Meconial peritonitis (PM) is localized or generalized peritonitis, aseptic, chemical or strange body; a product of meconium steps to the peritoneal cavity and is correlated with prenatal perforation of the digestive tract. It occurs in 1 in 30,000 newborns. Prenatal ultrasound diagnosis improves perinatal outcomes, the most frequent finding is ascites. PM requires urgent multidisciplinary treatment, most of cases need surgical resolution. OBJECTIVE To present an infrequent pathology, which requires a high degree of diagnostic suspicion to grant a specific and timely perinatal management. Clinical case Pregnant 29 years old woman without morbid history, 36 weeks of controlled pregnancy. Ultrasound control shown fetal ascites. He is hospitalized at high obstetric risk, ruling out metabolic and infectious pathology. At 37 weeks by emergency caesarean section, is obtained a baby boy with abdominal distension and hepatomegaly. In exploratory laparotomy there are undamaged intestinal handles. In re intervention it is noted herniated perforated distal ileum, ostomy is made. Patient evolves favourably and is discharged. DISCUSSION It is essential consider PM within the differential diagnoses of fetal ascites. An opportune diagnosis improves the perinatal results and could avoids possible complications.


Subject(s)
Humans , Female , Pregnancy , Infant, Newborn , Adult , Peritonitis/diagnosis , Peritonitis/etiology , Prenatal Diagnosis , Meconium , Peritonitis/surgery , Ascites/diagnosis , Diagnosis, Differential
2.
Arq. bras. med. vet. zootec. (Online) ; 71(5): 1518-1524, set.-out. 2019. tab, ilus
Article in Portuguese | LILACS (Americas), VETINDEX | ID: biblio-1038661

ABSTRACT

Nocardiose é causada por bactérias do gênero Nocardia do subgrupo Actinomycetos, que são Gram-positivas aeróbicas, filamentosas e podem apresentar ramificações. O diagnóstico baseia-se na presença de lesão inflamatória, com o microrganismo morfologicamente compatível, associada ao isolamento e à identificação microbiológica e molecular. Este trabalho tem por objetivo relatar um caso de nocardiose em canino, que desenvolveu inflamação piogranulomatosa peritoneal seis meses após ovariossalpingo-histerectomia. O animal apresentava hipertermia, distensão abdominal, taquipneia, polidipsia, hiporexia, mucosas hipocoradas e fezes pastosas. Os achados laboratoriais evidenciaram anemia leve e leucocitose por neutrofilia com desvio à esquerda e hipoalbuminemia. Uma massa na região mesogástrica e efusão peritoneal foram evidenciadas por meio da ultrassonografia abdominal. O líquido foi classificado como exsudato piogranulomatoso, e o animal submetido à laparotomia exploratória para lavagem abdominal e remoção da massa. Após procedimentos terapêuticos, ocorreu piora clínica e óbito. Peritonite piogranulomatosa foi a principal alteração anatomopatológica a qual foi associada à Nocardia spp. Molecularmente, a espécie isolada se aproxima da N. concava, por meio da análise filogenética. Essa espécie já foi descrita como causa de infecção em humanos na Ásia, no entanto não há registros na literatura na espécie canina, sendo este o primeiro relato.(AU)


Nocardiosis is caused by an aerobic, gram-positive, ramificated and filamentous bacteria of the Nocardia genus, subgroup Actinomycetos. The diagnosis is based on the presence of the inflammatory lesions with the morphologically compatible microorganism associated with microbiological and molecular isolation and identification. The objective of this work is to report a case of nocardiosis in a canine that developed peritoneal pyogranulomatous inflammation six months after ovariosalpingohisterectomy. The animal had hyperthermia, abdominal distention, tachypnea, polydipsia, hyporexia, hypocorous mucosae and pasty feces. The laboratory findings revealed mild anemia and leukocytosis due to neutrophilia with left deviation and hypoalbuminemia. A mass in the mesogastric region and peritoneal effusion were evidenced by abdominal ultrasonography. The fluid was classified as pyogranulomatous exudate and the animal underwent exploratory laparotomy for abdominal lavage and mass removal. Despite the therapeutic procedures and clinical alterations the dog died. Piogranulomatous peritonitis was the main anatomopathological alteration which was associated with Nocardia spp. Molecularly, the isolated species approaches the N. concava species through phylogenetic analysis. This specie was described as a cause of infection in humans in Asia; however, there are no records in literature on the canine species, being this the first report.(AU)


Subject(s)
Animals , Female , Dogs , Peritonitis/surgery , Peritonitis/diagnosis , Peritonitis/veterinary , Nocardia Infections/diagnosis , Nocardia Infections/veterinary
3.
Zagazig University Medical Journal ; 25(3), p.317-325, tab., 2019
Article in English | AIM (Africa) | ID: afr-200346

ABSTRACT

Background: Spontaneous Bacterial Peritonitis (SBP) is the most frequent bacterial infection in cirrhotic patients with ascites. The mortality rate in those patients ranges from 40-70%.Aim: to assess level of serum and ascetic fluid polymorph nuclear leucocytes (PMN), high sensitive C reactive protein (hs-CRP) in patients with SBP before and after treatment. Methods: A cohort study was done on 114 patients SBP admitted in the Internal Medicine, Faculty of Medicine, Zagazig University during the period from December 2017 to September 2018. All patients were subjected to full history taking, thorough clinical examination, routine laboratory investigation, ultrasonography and ascitic fluid sampling. They was followed up for 5 days from starting treatment by parenteral third generation cephalosporin and peripheral blood (PMN), serum (hs-CRP), ascitic fluid PMN and hs-CRP were measured again.Results: the largest percentage of the patients were male, had posthepatitic C cirrhosis and child C score. There was statistically non-significant difference between antibiotic responders and non-responders regarding peripheral blood PMN before or five days after antibiotic use. There was statistically non-significant difference in ascitic fluid PMN, serum and ascitic fluid hs-CRP before treatment while the difference is significant between both groups regarding them five days after treatment. Percent change in serum hs-CRP was equal to that of ascitic fluid PMN. Percent change in ascitic fluid hs-CRP was comparable to that of ascitic fluid PMN. Conclusion: Serum and ascitic fluid hs-CRP level can be considered as alternative prognostic markers in cirrhotic patients with SBP.


Subject(s)
Peritonitis/diagnosis , Peritonitis , /metabolism , Prognosis , Egypt
4.
Rev. cuba. cir ; 57(4): e732, oct.-dic. 2018. tab
Article in Spanish | LILACS (Americas) | ID: biblio-991048

ABSTRACT

Introducción: Las peritonitis secundarias son frecuentes y tienen una alta letalidad. Objetivo: Determinar los factores determinantes de la letalidad por peritonitis secundaria en la unidad de terapia intensiva del Hospital Dr. Agostinho Neto; desde 2015 hasta 2017. Método: Se realizó un estudio prospectivo y longitudinal con todos los pacientes egresados con diagnóstico de peritonitis secundaria (n= 70). Se agruparon según fueron egresados vivos o fallecidos. Se estudiaron las siguientes variables: edad, sexo, antecedentes patológicos personales, características de la peritonitis (manifestaciones clínicas, causa, resultado del cultivo de secreciones peritoneales, complicaciones, antimicrobianos utilizados y escalas de gravedad). Para el análisis estadístico se utilizó la frecuencia absoluta, el porcentaje y riesgo absoluto. Resultados: Los pacientes se caracterizaron sobre todo por presentar fiebre, leucocitosis con desviación izquierda y por la realización del control foco séptico peritoneal (100 por ciento); en los fallecidos, los más común fue que presentaron fallo multiorgánico, en el líquido peritoneal se aisló un microorganismo de la especie Acinetobacter y manifestaron inmunodepresión, variables para las que la letalidad asociada fue de 94,7 por ciento, 80,0 por ciento y 71,4 por ciento, respectivamente. Conclusiones: Los factores más asociados a la letalidad fueron los siguientes: fallo multiorgánico, hipoxemia menor o igual a 85 mmHg y/o saturación periférica de oxígeno menor o igual 90 por ciento, tiempo evolución manifestaciones clínicas antes de la cirugía mayor o igual 24 horas, choque séptico, edad mayor o igual 60 años, presión intra abdominal poscirugía mayor o igual 21 cm H2O, origen colónico de la peritonitis y la presencia de fluido peritoneal fecaloideo(AU)


ABSTRACT Introduction: Secondary peritonitis is frequent, with high mortality indexes. Objective: To establish the determining factors of the secondary peritonitis mortality in the intensive care unit of Dr Agostinho Neto hospital. Method: A prospective longitudinal study was conducted in all the patients discharged from hospital with diagnosis of secondary peritonitis (n=70). They were grouped into dead or alive patients. The following variables were studied: age, sex, personal pathological history and characteristics of peritonitis (clinical signs, causes, results of the peritoneal secretion culture, complications, antimicrobials used in treatment and severity scales). The statistical analysis was based on absolute frequencies, percentages and absolute risk. Results: The patients were characterized by presenting with fever and leukocytosis with left deviation and by performance of peritoneal septic focus control (100 percent). The multi-organ failure was common in dead patients. Acinetobacter species microorganism was isolated in the peritoneal fluid in addition to presenting immunosuppression; the associated mortality rates for these variables were 94.7 percent, 80 percent and 71.4 percent, respectively. Conclusions: The most associated factors to mortality were multi-organ failure, hypoxemia lower than or equal to 90 percent, time of progression, clinical signs present for 24 hours or longer before the surgery, septic shock, age of 60 years or older, post-surgery intra-abdominal pressure equal to or over 21 cm H2O, colonic origin of peritonitis and presence of fecaloid peritoneal fluid(AU)


Subject(s)
Humans , Peritonitis/diagnosis , Intensive Care Units/statistics & numerical data , Hypoxia/mortality , Multiple Organ Failure/mortality , Prospective Studies , Longitudinal Studies
5.
Rev. habanera cienc. méd ; 17(1): 91-102, ene.-feb. 2018. ilus
Article in Spanish | LILACS (Americas), CUMED | ID: biblio-901802

ABSTRACT

Introducción: La peritonitis postoperatoria es una de las complicaciones más frecuentes que se presenta tras procederes laparoscópicos. Objetivo: Caracterizar la evolución de los pacientes complicados con peritonitis después de un proceder laparoscópico. Material y método: Se realizó un estudio observacional descriptivo de los pacientes con peritonitis ingresados en la terapia intensiva, del Centro Nacional de Cirugía de Mínimo Acceso, desde septiembre de 2010 hasta diciembre de 2015. Se analizaron algunas variables demográficas, procederes laparoscópicos que se complicaron con este diagnóstico, complicaciones clínicas, antibioticoterapia utilizada, tipo de nutrición y la escala de evaluación fisiológica APACHE II como predictor de pronóstico. La información se obtuvo de las historias clínicas. Las variables cualitativas se resumieron utilizando frecuencias absolutas y porcentajes. Para las cuantitativas se utilizó la media y la desviación estándar. Resultados: Se complicaron con peritonitis 26 de 298 pacientes ingresados en el período (8,7 ), la edad media fue de 60 años, predominó el sexo femenino (57,7 por ciento). Se complicaron más con este diagnóstico los pacientes perforados postcolonoscopia (50 por ciento). El disbalance hidroelectrolítico (73,1 por ciento) fue la complicación asociada más frecuente. Se usó precozmente la nutrición enteral en 57,7 por ciento y los antibióticos más utilizados fueron ceftriaxone, amikacina y metronidazol. Predominó la evolución favorable a pesar que el score APACHE II se mantuvo en valores elevados. Conclusiones: Las perforaciones intestinales después de una colonoscopía tienen un alto riesgo de sufrir peritonitis secundaria, pero si se realiza un diagnóstico y tratamiento precoz su evolución es favorable(AU)


Introduction: Endoscopic dilatation is the first therapeutic option to eliminate benign esophageal stenosis and improve the symptoms and the quality of life of those patients who suffer from it. Objective:To describe the results of endoscopic dilatation in patients with benign esophageal stenosis treated in the National Center for Endoscopic Surgery from January 2015 to December 2016. Material and Methods:A case series longitudinal observational study was conducted in 59 patients with benign esophageal stenosis. Dilatations were done with Savary-Gilliard bougie and balloons. Results:The mean age was 52,5 years, and the condition predominated in 37 male patients (62,7 percent). Post-surgical, peptic, and caustic were the most frequent etiologies with 25, 14, and 6 cases, respectively. Short stenosis predominated in 51 cases. Bougies were used in 48 patients for a total of 149 dilatations, corresponding to a mean of 3,1 dilatations/ patients. Correction of the stenosis was made in 1-3 sessions in 47 percent of patients; 11 cases were dilated with balloon, corresponding to a mean of 1- 3 dilatations/ patients. Four patients from the group that were dilated with Savary-Gilliard bougies showed refractoriness. A perforation, and two bleedings occurred. After the dilatations, dysphagia improved or disappeared in 93,2 percent of patients. Conclusions:Endoscopic therapy through dilatation of benign esophageal stenosis indicated to be a good alternative method in achieving corrections in a few dilatation sessions, with a low number of complications, and an improvement of the dysphagia(AU)


Subject(s)
Humans , Male , Female , Peritonitis/surgery , Peritonitis/diagnosis , Peritonitis/prevention & control , Early Diagnosis , Clinical Evolution/methods , Epidemiology, Descriptive , Laparoscopy/methods , Critical Care/methods , Observational Study
6.
REME rev. min. enferm ; 21: [1-7], 2017. tab
Article in English, Portuguese | LILACS (Americas), BDENF | ID: biblio-907933

ABSTRACT

Objetivo: analisar a taxa das peritonites no Serviço de Diálise Peritoneal de um Hospital-Escola e conhecer o perfil dos pacientes do programa de diálise peritoneal. Metodologia: estudo observacional, descritivo, retrospectivo, de natureza quantitativa, realizado no serviço de diálise no interior de São Paulo de janeiro a dezembro de 2015. RESULTADOS: dos 39 pacientes em diálise peritoneal, 51,3% eram do sexo masculino, 64,1% não idosos, 51,3% procediam de outros municípios, 69,2% aposentados, 66,7% estavam em diálise peritoneal ambulatorial contínua, 43,6% estavam em tratamento de um a dois anos e 79,5% não estavam na lista de transplante, sendo 41% em virtude de início recente na terapia. Dos 20 pacientes que apresentaram peritonite, 50% tiveram dois episódios no ano, 20% causados por Staphylococcus aureus. Em 90% o antibiótico foi administrado por via endovenosa, 95% tiveram associação de antibióticos, sendo os mais comuns ceftazidima, vancomicina e cefalotina. Dos 90% dos pacientes que saíram da terapia, 65% eram do sexo feminino, 55% moravam no município da instituição de tratamento, 70% eram aposentados e 65% estavam em diálise peritoneal ambulatorial contínua, com média de idade de 56 anos (DP=14,6 anos) e média de 1,7 ano de tratamento. A taxa de peritonite em diálise peritoneal ambulatorial contínua e diálise peritoneal automatizada foi de 2,79% e em diálise peritoneal intermitente 13,33%. CONCLUSÃO: a maioria dos pacientes que teve peritonite eram mulheres. A média de peritonites foi maior entre as pessoas com menos idade e menos tempo de tratamento e 90% dos pacientes saíram da terapia.


Objective: analyze peritonitis rates in the Peritoneal Dialysis Service of a university hospital and identify the profile of patients attending the peritoneal dialysis program. Methods: This observational, retrospective, and descriptive study with a quantitative approach was conducted at adialysis service in the interior of São Paulo, Brazil, from January to December 2015. Results: Of the 39 patients on peritoneal dialysis, 51.3% were men;64.1% were non-elderly patients; 51.3% were from towns other than where the service was located; 69.2% were retired; 66.7% were in continuous ambulatory peritoneal dialysis; the duration of treatment of 43.6% ranged from one to two years; 79.5% were not on the transplant waiting list;and 41% had recently started therapy. Of the 20 patients presenting peritonitis, 50% had two episodes and 20% of the episodes were causedby Staphylococcus aureus. The antibiotic was administered intravenously in 90% of the patients; antibiotics were associated with ceftazidime, vancomycin or cephalothin (the most common ones) in 95%. Among those who dropped out of therapy (90%): 65% were women, 55% lived in thesame town as the health facility; 70% were retired; 65% were undergoing continuous ambulatory peritoneal dialysis, and were aged 56 years old onaverage, while treatment duration was 1.7 years on average. The peritonitis rate among those on continuous ambulatory peritoneal dialysis andautomated peritoneal dialysis was 2.79%, while 13.33% were on intermittent peritoneal dialysis. Conclusion: Most patients with peritonitis werewomen, lived in the same town as the facility, were retired and underwent continuous ambulatory peritoneal dialysis, and treatment duration was1.7 years on average, and 90% of the patients dropped out of therapy.


Objetivo: analizar la tasa de peritonitis en el servicio de diálisis peritoneal de un hospital escuela; conocer el perfil de los pacientes del programa dediálisis peritoneal. Metodología: Estudio observacional, descriptivo, retrospectivo, cuantitativo realizado en el servicio de diálisis de un hospital delinterior del estado de São Paulo, entre enero y diciembre de 2015. Resultados: De los 39 pacientes en diálisis peritoneal, 51,3% eran varones, 64,1% noancianos, 51,3% venían de otros municipios, 69,2% jubilados, 66,7% en diálisis peritoneal continua ambulatoria, 43,6% en tratamiento entre uno y dosaños,79,5% no estaban en la lista de trasplantes y, entre ellos, 41% habían reiniciado recientemente el tratamiento. De los 20 paciente que presentaron peritonitis, 50% tuvieron dos episodios en el año, 20% causado por Staphylococcus aureus. En 90%, el antibiótico se administró vía venosa, 95%tuvieron asociación de antibióticos, siendo los más comunes ceftazidima, vancomicina y cefalotina, y 90% de los pacientes interrumpieron la terapia,65% eran mujeres, 55% vivían en el municipio de la institución de tratamiento, 70% eran jubilados y 65% estaban en CAPD con promedio de 56 añosde edad y 1,7 años de tratamiento. La tasa de peritonitis en diálisis peritoneal continua ambulatoria y diálisis peritoneal automatizada fue de 2,79%y en diálisis peritoneal intermitente 13,33%. Conclusión: Entre los pacientes con peritonitis, la mayoría eran mujeres, el promedio de peritonitis fuemayor entre las personas más jóvenes y con menos tiempo de tratamiento y 90% de los pacientes interrumpieron el tratamiento.


Subject(s)
Humans , Male , Female , Peritoneal Dialysis , Peritonitis/diagnosis , Peritonitis/epidemiology , Peritonitis/prevention & control , Renal Insufficiency, Chronic/complications , Socioeconomic Factors
7.
Gastroenterol. latinoam ; 28(2): 85-87, 2017.
Article in Spanish | LILACS (Americas) | ID: biblio-1118650

ABSTRACT

Spontaneous bacterial peritonitis (SBP) is a frequent and severe complication in cirrhotic patients. Listeria monocytogenes is a rare cause of SBP, which should be suspected in individuals with impaired immunity such as advanced liver disease and inadequate response to standard antibiotic therapy. We report a case of a 72 year-old patient with liver cirrhosis secondary to alcohol consumption, asymptomatic carrier of Hepatitis B virus, diabetes Type II and coronary artery disease; who is admitted with a diagnosis of hepatic encephalopathy and suspicion of spontaneous bacterial peritonitis receiving empiric antibiotic treatment with ceftriaxona. Initially he showed clinical response but a few days later he got worse. Ascitic culture confirmed infection by Listeria monocytogenes. Antibiotic treatment was adjusted but patient continued deteriorating progressively, and finally died due to renal dysfunction.


La peritonitis bacteriana espontánea (PBE) es una complicación frecuente y grave en los pacientes cirróticos. Listeria monocytogenes es una causa poco frecuente de PBE, que debe sospecharse en individuos con inmunidad alterada como es la enfermedad hepática avanzada y con respuesta inadecuada a terapia antibiótica habitual. Presentamos el caso de un paciente de 72 años con antecedentes de cirrosis hepática secundaria a consumo de alcohol, portador asintomático del virus de la Hepatitis B (VHB), diabético tipo II y cardiópata coronario. Se hospitaliza por encefalopatía hepática secundaria a PBE, recibe tratamiento antibiótico empírico con ceftriaxona con respuesta clínica inicial y deterioro posterior. Cultivo de líquido ascítico confirma infección por Listeria monocytogenes. Pese a ajuste de tratamiento antibiótico, continúa empeorando y finalmente fallece por disfunción renal.


Subject(s)
Humans , Male , Aged , Peritonitis/drug therapy , Listeria monocytogenes/drug effects , Liver Cirrhosis/complications , Anti-Bacterial Agents/administration & dosage , Anti-Bacterial Agents/therapeutic use , Peritonitis/diagnosis , Peritonitis/microbiology , Treatment Outcome , Listeriosis/microbiology , Listeria monocytogenes/isolation & purification , Liver Cirrhosis, Alcoholic/complications , Liver Diseases/drug therapy
8.
Cir. parag ; 40(1): 21-24, mayo. 2016.
Article in Spanish | LILACS (Americas), BDNPAR | ID: biblio-972583

ABSTRACT

Las lesiones vesicales son causadas por traumatismos cerrados de alta energía que interrumpen la pelvis ósea, un golpe directo a una vejiga distendida, lesiones penetrantes o causas iatrogénicas varias. 1 Se presenta el caso de una paciente de sexo femenino, joven, con patología de base en estudio por el Servicio de Urología, quien en el contexto del diagnóstico de dicha patología fue sometida a un procedimiento urológico invasivo (RTU), con abdomen peritoneal 24hs después del procedimiento. En el acto quirúrgico se constató aproximadamente 1000cc de orina y perforación vesical de 1cm de diámetro con mucosa exteriorizada hacia cavidad peritoneal. Se realizó biopsia de la mucosa vesical, rafia de la perforación en un plano, lavado y aspirado de cavidad por videolaparoscopía, y colocación de drenaje tubular y sonda vesical en permanencia.


Bladder injuries are caused by high energy blunt trauma thatdisrupt the pelvis bone, a direct blow to a distended bladder, penetratinginjuries or some iatrogenic causes. The case of a youngfemale patient, underlying pathology study by the Department ofUrology, who in the context of diagnosis of this disease underwenta urological invasive procedure (TUR), with peritoneal abdomenpresents 24 hours after the procedure. During surgery it was foundabout 1000cc of urine and bladder perforation 1 cm in diameterwith externalized mucosa into peritoneal cavity. Biopsy of bladdermucosa, closure of defect with absorbable material and drainage ofthe cavity was performed entirely by videolaparoscopy.


Subject(s)
Female , Humans , Adult , General Surgery , Peritonitis/diagnosis , Peritonitis/surgery
9.
Journal of Infection and Public Health. 2016; 9 (2): 192-197
in English | IMEMR (Eastern Mediterranean) | ID: emr-176303

ABSTRACT

Nocardia asteroides is a rare pathogen in peritoneal dialysis-related peritonitis. We report on a 13-year-old female with Nocardia asteroides peritonitis complicated by an intra-abdominal abscess. Linezolid was administered intravenously for 3 months and followed by oral therapy for an additional 5 months with close monitoring for adverse effects. The patient was discharged after 3 months of hospitalization on hemodialysis. The diagnosis and management of such cases can be problematic due to the slow growth and difficulty of identifying Nocardia species. The optimal duration of treatment for Nocardia peritonitis is not known. Linezolid can be used for prolonged periods in cases of trimethoprim/sulfamethoxazole-resistant cases with close monitoring for adverse effects


Subject(s)
Humans , Female , Adolescent , Peritonitis/diagnosis , Peritoneal Dialysis , Pediatrics , Linezolid/therapeutic use , Abdominal Abscess , Tomography, X-Ray Computed
10.
Arq. gastroenterol ; 52(3): 195-199, July-Sep. 2015. tab
Article in English | LILACS (Americas) | ID: lil-762877

ABSTRACT

BackgroundSpontaneous bacterial peritonitis is defined as an ascetic fluid infection without an evident intra-abdominal surgically treatable source. Spontaneous bacterial peritonitis is one of the severe complications in patients with cirrhosis and ascites. Without early antibiotic treatment, this complication is associated with high mortality rate; therefore, early diagnosis and treatment of spontaneous bacterial peritonitis is necessary for survival. Leukocyte esterase reagent can rapidly diagnose the spontaneous bacterial peritonitis.ObjectiveThis study aimed to find out the diagnostic accuracy of leukocyte esterase dipstick test for the diagnosis of spontaneous bacterial peritonitis.MethodsA single centered hospital-based cross-sectional study was conducted during July 2013 to August 2014 on children with cirrhotic liver disease and ascites who were admitted in the Department of Pediatric Gastroenterology in Nemazee Hospital affiliated to Shiraz University of Medical Sciences (Iran). All patients underwent abdominal paracentesis, and the ascitic fluid was processed for cell count, leukocyte esterase reagent strip test (Combiscreen SL10) and culture. Spontaneous bacterial peritonitis was defined as having a polymorphonuclear count (PMN ≥250/m3) in ascitic fluid. Sensitivity, specificity, positive predictive value and negative predictive value of leukocyte esterase test were calculated according to the formula.ResultsTotally, 150 ascitic fluid sample of cirrhotic male patients (53.2%) and their mean age (4.33±1.88 years) were analyzed. Biliary atresia (n=44, 29.4%) and idiopathic neonatal hepatitis (n=29, 19.3%) were the most frequent etiology of cirrhosis. Also, abdominal pain (68.6%) and distension (64%) were the most common presenting complaint. Of all cases, 41patients (27.35%) were diagnosed to have spontaneous bacterial peritonitis (PMN ≥250/mm3). Sensitivity and specificity of leukocyte esterase reagent test according to PMNs ≥250mm3 were 87.80% and 91.74%, also on ascitic fluid culture results were 88.23% and 77.44%. Positive predictive value and negative predictive value of this test in PMNs ≥250mm3 were 80% and 95.23% and in cases with positive culture 33.33% and 98.09% were obtained, respectively. Efficiency of leukocyte esterase reagent test in diagnosing spontaneous bacterial peritonitis, according to PMNs ≥250mm3 and culture results were 90.66% and 78.66%.ConclusionThe leukocyte esterase strip test may be used as rapid test for diagnosis of spontaneous bacterial peritonitis due to its high diagnostic validity.


ContextoA peritonite bacteriana espontânea é definida como uma infecção do fluido ascítico sem evidente origem intra-abdominal cirurgicamente tratável. A peritonite bacteriana espontânea é uma das complicações graves em pacientes com cirrose e ascite. Sem tratamento antibiótico precoce, esta complicação é associada com alta taxa de mortalidade. Portanto, o diagnóstico precoce e tratamento de peritonite bacteriana espontânea são necessários para a sobrevivência. O reagente de esterase de leucócitos pode rapidamente diagnosticar a peritonite bacteriana espontânea.ObjetivoEste estudo teve como objetivo descobrir a acurácia diagnóstica do teste com tiras de esterase de leucócitos para o diagnóstico de peritonite bacteriana espontânea.MétodosUm estudo transversal hospitalar unicêntrico foi realizado entre julho de 2013 e agosto de 2014 em crianças com cirrose hepática e ascite que foram admitidas no Departamento de Gastroenterologia Pediátrica no Hospital de Nemazee afiliado à Universidade de Ciencias Médicas de Shiraz (Irã). Todos os pacientes foram submetidos a paracentese abdominal, e o líquido ascítico foi processado para contagem de células, teste de tira de reagente de esterase de leucócitos (Combiscreen SL10) e cultura. Peritonite bacteriana espontânea foi definida como tendo uma contagem de polimorfonucleares (PMN ≥250/m3) no líquido ascítico. Sensibilidade, especificidade, valor preditivo positivo negativo do teste de esterase de leucócitos foram calculados de acordo com a fórmula.ResultadosForam analisados um total de 150 amostras de líquido ascítico de pacientes cirróticos; (53,2%) eram do sexo masculino e sua média de idade (4,33±1,88 anos). A atresia biliar (n=44, 29,4%) e hepatite neonatal idiopática (n=29, 19,3%) foram as etiologias mais frequentes de cirrose. Além disso, dor abdominal (68,6%) e distensão (64%) foram as queixas mais comuns de apresentação. De todos os casos, 41 (27,35%) foram diagnosticados com peritonite bacteriana espontânea (PMN ≥250/mm3). A sensibilidade e especificidade do teste de reagente de esterase de leucócitos segundo PMN ≥250mm3 foi de 87,80% e 91,74% e, para os resultados de cultura de líquido ascítico, de 88,23% e 77,44%. Valor preditivo positivo e valor preditivo negativo do teste em PMN ≥250mm3 foi de 80% e 95,23% e em casos com cultura positiva 33,33% e 98,09%, respectivamente. A eficiência do teste de reagente esterase de leucócitos no diagnóstico de peritonite bacteriana espontânea, de acordo com resultados de ≥250mm3 e cultura PMN, foi de 90,66% e 78,66%.ConclusãoO teste de tiras de esterase de leucócitos pode ser usado como um teste rápido para diagnóstico de peritonite bacteriana espontânea, devido a sua alta validade diagnóstica.


Subject(s)
Female , Humans , Male , Ascites/complications , Carboxylic Ester Hydrolases , Liver Cirrhosis/complications , Peritonitis/diagnosis , Peritonitis/etiology , Reagent Strips , Ascitic Fluid , Ascites/microbiology , Bacterial Infections/microbiology , Cross-Sectional Studies , Peritonitis/microbiology , Sensitivity and Specificity
11.
Gac. méd. espirit ; 17(2): 65-73, mayo.-ago. 2015. ilus, graf, mapas, tab
Article in Spanish | LILACS (Americas) | ID: lil-759138

ABSTRACT

Fundamento: La peritonitis secundaria a apendicitis aguda perforada por esquistosomiasis es una entidad muy rara, pocos casos han sido descritos en la literatura; esta parasitosis proviene de zonas endémicas y con tratamiento antihelmíntico remite hasta su curación, evitando su propagación y complicaciones, que son mortales en estadíos avanzados. Objetivo: Describir el caso de un paciente con peritonitis secundaria a apendicitis aguda perforada por esquistosomiasis. Presentación de caso: Hombre filipino, saludable, de 42 años, con dolor abdominal difuso e intenso de cinco días de evolución, acompañado de vómitos y fiebre e intensa reacción peritoneal, constatada al examen físico, en la tomografía computarizada contrastada de abdomen se visualizó el apéndice engrosado así como colección de líquido intraabdominal. Se realizó laparotomía exploradora, apendicectomía y lavado de la cavidad abdominal. El estudio histopatológico informó, apendicitis perforada con presencia de huevos de Schistosoma en las paredes del apéndice Conclusiones: El paciente evolucionó favorablemente y sin complicaciones posoperatorias, se egresó a los diez días después de terminado el tratamiento antibiótico y antihelmíntico con prazicuantel.


Background: Secondary peritonitis and acute appendicitis percuss by schistosomiasis is a rare entity , few cases have been described in literature , this parasitoids comes from endemic zones and with an antihelmintic treatment letting up to its cure , avoiding its propagation and complications , which are mortal in advanced stages. Objectives: to describe the case of a patient with Secondary peritonitis and acute appendicitis percuss by schistosomiasis. Case report: A filipine healthy man, 42 years old, with an abdominal diffuse and intense pain of 5 days of evolution, together with vomits, fever and intense peritoneal reaction, palpable in the physical exam, in the contrasted computer tomography of abdomen was observed an enlarged appendix as well as collection of intraabdominal liquid. An explore laparotomy, an appendectomy, a wash of the abdominal cavity, and the histopathology reported percuss appendicitis with presence of schitosoma eggs on the walls of the appendix. Conclusions: The patient evoluted favorably and without post operatory complications, egress 10 days after having finished the antibiotic and the antihelmintic treatment with praziquantel.


Subject(s)
Humans , Appendicitis/surgery , Appendix/surgery , Schistosomiasis , Appendectomy/instrumentation , Peritonitis/diagnosis
13.
Säo Paulo med. j ; 132(4): 205-210, 07/2014. tab, graf
Article in English | LILACS (Americas) | ID: lil-714883

ABSTRACT

CONTEXT AND OBJECTIVE: Spontaneous bacterial peritonitis (SBP) is a severe complication that occurs in 8-27% of hospitalized patients with liver cirrhosis and ascites, with high mortality rates. This study aimed to identify the clinical characteristics associated with SBP. DESIGN AND SETTING: Cross-sectional study, conducted in a public university. METHODS: The study consecutively included individuals with liver cirrhosis and ascites between September 2009 and March 2012. Forty-five patients were included: mean age 53.2 ± 12.3 years, 82.2% male, 73.8% Caucasian, mean Model of End-stage Liver Disease (MELD) score of 19.5 ± 7.2, and 33.3% with SBP. The subjects were divided into two groups: SBP and controls. RESULTS: Comparison between individuals with SBP and controls showed that those with SBP had lower mean prothrombin activity time (36.1 ± 16.0% versus 47.1 ± 17.2%; P = 0.044) and lower median serum-ascites albumin gradient (SAAG) (1.2 versus 1.7, P = 0.045). There was a tendency towards higher mean MELD in the SBP group, not significant (22.2 ± 7.6 versus 17.9 ± 6.7; P = 0.067). There was a strong positive correlation between the neutrophil count in ascitic fluid and serum leukocyte count (r = 0.501; P = 0.001) and a negative correlation between the neutrophil count in ascitic fluid with prothrombin activity time (r = -0.385; P = 0.011). CONCLUSION: A few characteristics are associated with the presence of SBP, especially liver dysfunction, SAAG and peripheral leukocytosis. .


CONTEXTO E OBJETIVO: Peritonite bacteriana espontânea (PBE) é uma complicação grave que ocorre em 8-27% dos pacientes hospitalizados com cirrose hepática e ascite, e apresenta altas taxas de mortalidade. O objetivo deste estudo é identificar as características clínicas associadas à PBE. TIPO DE ESTUDO E LOCAL: Estudo transversal, conduzido em uma universidade pública. MÉTODOS: O estudo incluiu, consecutivamente, indivíduos com cirrose hepática e ascite entre setembro 2009 e março 2012. Foram incluídos 45 indivíduos com média de idade de 53,2 ± 12,3 anos, sendo 82,2% homens, 73,8% brancos, com MELD (Modelo para Doença Hepática Terminal) de 19,5 ± 7,2, e 33,3% com PBE. Os indivíduos foram divididos em dois grupos: PBE e controles. RESULTADOS: Quando se compararam os indivíduos com PBE aos controles, observou-se menor média de tempo de atividade da protrombina (TAP; 36,1 ± 16,0% versus 47,1 ± 17,2%; P = 0,044) e menor mediana de gradiente albumina soro-ascite (GASA; 1,2 versus 1,7; P = 0,045). Houve tendência do grupo com PBE de apresentar maior média de MELD, sem significância estatística (22,2 ± 7,6 versus 17,9 ± 6,7; P = 0,067). Foi observada forte correlação positiva entre neutrófilos do líquido ascítico e contagem sérica de leucócitos (r = 0,501; P = 0,001) e correlação negativa de neutrófilos do líquido ascítico com TAP (r = -0,385; P = 0,011). CONCLUSÃO: Poucas características estão associadas à presença de PBE, em especial a disfunção hepática, o GASA e a leucocitose periférica. .


Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Ascites/complications , Bacterial Infections/diagnosis , Liver Cirrhosis/complications , Peritonitis/diagnosis , Ascitic Fluid , Brazil , Bacterial Infections/etiology , Cross-Sectional Studies , Hospitals, University , Leukocytes , Medical Records , Neutrophils/pathology , Prothrombin Time , Paracentesis/methods , Peritonitis/etiology , Severity of Illness Index
14.
Cir. parag ; 38(1): 18-21, jun. 2014. ilus
Article in Spanish | LILACS (Americas), BDNPAR | ID: biblio-972557

ABSTRACT

Antecedentes: La peritonitis aguda secundaria (PAS) es una emergencia común y su tratamiento fundamental es la intervención quirúrgica. Sin embargo a pesar de los avances en las técnicas quirúrgicas; la antibiótico-terapia y el soporte de los cuidados intensivos conlleva una alta morbilidad y mortalidad, siendo su manejo difícil y complejo. PACIENTES Y MÉTODO: 99 casos de PAS sometidos a laparotomía en el período 2006-2010 (56 varones y 43 mujeres) son analizados de manera retrospectiva en un estudio descriptivo que tiene como objetivo identificar las causas más frecuentes, establecer el porcentaje de certeza diagnóstica preoperatoria, investigar las complicaciones postoperatorias, evaluar factores pronósticos de mortalidad según el índice de Mannheim y determinar la mortalidad. RESULTADOS: La principal causa de peritonitis secundaria fue la apendicular (19%), seguida de peritonitis postoperatoria (17%), en tercer lugar, la perforación de úlcera gastroduodenal, y de asas delgadas (16% cada una), luego, la peritonitis de origen ginecológico (12%), seguidas por las de origen colónico (10%). El tratamiento más frecuente fue el control del foco de contaminación, lavado y secado, con cierre de la cavidad peritoneal (93%). El abdomen abierto, contenido con bolsa de Bogotá se utilizó en 7% de los casos. La mortalidad asociada con la peritonitis secundaria fue de 16%. CONCLUSIONES: Las causas más frecuentes de peritonitis secundaria, fueron, la apendicular, seguidas de las peritonitis postoperatorias. El porcentaje de certeza diagnóstica preoperatoria encontrado en esta serie fue del 27%. Las complicaciones más frecuentes del foco operatorio fueron las dehiscencias de suturas, seguidas de las colecciones a nivel del lecho operatorio


Background: Acute secondary peritonitis (ASP) is a common emergency, its fundamental treatment is surgical intervention, whoever despite the advances on surgical techniques, antibiotic-therapy and intensive care support; mortality and morbidity stay high, while its management remain difficult and complex. PATIENTS AND METHOD: 99 patients with ASP, that underwent laparotomy at the First Department of Surgical Clinics, during the 2006-2010 period (56 males and 43 females) were retrospectively studied with the purpose of identify the main causes, establish the accuracy of preoperative diagnosis, investigate postoperative complications, evaluate prognosis factors of mortality according to the Mannheim index and determinate the mortality. RESULTS: Perforated appendix, was the cause in 19%, follow by postoperative peritonitis (17%), in third place, perforation of the stomach and duodenum and small intestine (16%, each), follow by female internal genital organs (12%) and perforation of the colon (10%). The main treatment was controlling the local point of contamination, with primary close of the peritoneal cavity (93%), Open abdomen contain by Bogotá bag was used in 7% of the cases. The associated mortality was 16%. CONCLUSIONS: Main causes of secondary peritonitis were the appendix, follow by postoperative peritonitis. The preoperative diagnosis accuracy was 27%. The main complications found were suture failure, follow by intra-abdominal collections.


Subject(s)
Male , Female , Humans , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Peritonitis/diagnosis , Peritonitis/mortality , Peritonitis/surgery
15.
Rev. méd. Chile ; 142(2): 255-260, feb. 2014. ilus
Article in English | LILACS (Americas) | ID: lil-710996

ABSTRACT

Lupus peritonitis (LP) is extremely rare. Acute LP is characterized by rapid onset of ascites and severe abdominal pain, in addition to other well-recognized clinical features of a general systemic lupus erythematosus (SLE) fare. Ascites associated with acute LP has been rarely reported as the prominent feature of a SLE fare. We report a 39-year-old woman who developed massive, painful ascites as the presenting manifestation of a SLE fare. Diagnostic workup ruled out the possibility of hepatic, cardiovascular, infectious, or malignant diseases, and confirmed the presence of a SLE fare. The patient was treated with methyl prednisolone and hydroxychloroquine resulting in dramatic improvement of her condition. During ambulatory follow up, she has remained asymptomatic up to the moment of this writing. Adrenal steroids and hydrocychloroquine may be useful for the management of SLE fares in patients with massive, painful ascites due to acute LP.


La peritonitis lúpica es rara. El cuadro agudo se caracteriza por ascitis de comienzo rápido, dolor abdominal severo y otras manifestaciones de una recidiva de un lupus eritematoso sistémico (LES). Sólo ocasionalmente e ha informado que la ascitis y peritonitis lúpica sean las principales manifestaciones de una recidiva lúpica. Presentamos a una mujer de 39 años que presentó ascitis masiva y dolorosa como la primera manifestación de una reactivación lúpica. El estudio diagnóstico descartó problemas hepáticos, pulmonares, cardiacos, cáncer o infecciones y confirmó la reactivación lúpica. La paciente se trató con metilprednisolona y cloroquina, resultando en una mejoría dramática. Al momento de preparar este informe, la paciente permanece asintomática en control ambulatorio. Los corticoides y cloroquina pueden ser medicamentos útiles para el tratamiento de pacientes con ascitis dolorosa y masiva secundaria a peritonitis lúpica.


Subject(s)
Adult , Female , Humans , Ascites/etiology , Lupus Erythematosus, Systemic/complications , Peritonitis/etiology , Ascites/diagnosis , Peritonitis/diagnosis , Tomography, X-Ray Computed
16.
Article in English | WPRIM (Western Pacific) | ID: wprim-22043

ABSTRACT

Spontaneous bacterial peritonitis (SBP) is the most common infection in liver cirrhosis patients, and is not a result of surgery or intra abdominal infection. Argon plasma coagulation (APC) is an endoscopic procedure used with a high-frequency electrical current for control of bleeding from gastrointestinal vascular ectasias including angiodysplasia and gastric antral vascular ectasia. This procedure is known to be safe because it uses a noncontact method. Therefore, tissue injury is minimal and up to two to three millimeters. However, we experienced a case of SBP occurring immediately after performance of APC for control of severe bleeding from angiodysplasia in the colon in a patient with liver cirrhosis and hepatocellular carcinoma.


Subject(s)
Aged , Angiodysplasia/complications , Anti-Bacterial Agents/therapeutic use , Argon Plasma Coagulation , Bacterial Infections/diagnosis , Carcinoma, Hepatocellular/complications , Colonic Diseases/complications , Colonoscopy , Female , Gastrointestinal Hemorrhage/therapy , Gram-Negative Bacteria/isolation & purification , Humans , Liver Cirrhosis/complications , Liver Neoplasms/complications , Peritonitis/diagnosis
18.
Botucatu; s.n; 2013. 49 p. ilus, tab.
Thesis in Portuguese | LILACS (Americas) | ID: lil-756023

ABSTRACT

Peritonites e infecções do orifício de saída do cateter de diálise representam as principais complicações infecciosas relacionadas à diálise peritoneal, frequentemente respondem pela falência deste método dialítico, portanto com importante impacto na morbidade e mortalidade dos pacientes. Existem associações entre o portador de S. aureus e aumento no risco de infecções nos pacientes tratados por diálise peritoneal. Entretanto, desconhecemos estudos que avaliaram a virulência de Staphylococcus spp. carreados. Fatores de virulência são descritos como responsáveis pelos sintomas e gravidade de diversas infecções causadas por S. aureus. Esses fatores incluem as hemolisinas α, β, γ e δ, lipases, lecitinases, proteases, toxina 1 da Síndrome do Choque tóxico (TSST-1) e as enterotoxinas estafilocócicas (EEs), desoxirribonuclease (DNAse) e de desoxirribonuclease termoestável (TNAse). Este estudo teve como objetivo avaliar se fatores de virulência produzidos por Staphylococcus spp. e as características clinicas e epidemiológicas dos pacientes podem influenciar na ocorrência de infecções relacionadas ao tratamento. Para tal, foram incluídos 32 pacientes tratados por diálise peritoneal na Unidade de Diálise do Hospital das Clínicas da Faculdade de Medicina de Botucatu- UNESP, avaliados primariamente quanto à colonização (culturas de coletas nasais e pele pericateter, em três momentos distintos no período de 12 meses) e subsequentemente foram observados quanto ao risco para a ocorrência de infecções, acompanhados por até 36 meses confirmados com culturas do efluente peritoneal na ocorrência de peritonites e secreção da pele pericateter na vigência de infecção de orifício de saída do cateter...


Peritonitis and infections in the exit orifice of the dialysis catheter represent the main infectious complications related to peritoneal dialysis, and are often responsible for the failure in this dialysis method, therefore with a significant impact on morbidity and mortality of patients. There are associations between the carrier of S. aureus and increased risk of infection in peritoneal dialysis patients. However, studies that evaluated the virulence of Staphylococcus spp. carried are not aware. Virulence factors are described as responsible for the symptoms and severity of different infections caused by S. aureus. These factors include hemolysins α, β, and δ, lipases lecithinases, proteases, toxin 1 in Toxic Shock Syndrome (TSST-1) and staphylococcal enterotoxins (SEs), deoxyribonuclease (DNase) and thermostable deoxyribonuclease (TNAse). This study aimed to evaluate whether virulence factors produced by Staphylococcus spp. and the clinical and epidemiological characteristics of patients may influence the occurrence of infections related to the treatment. In order to do this, 32 patients treated by peritoneal dialysis at the Dialysis Unit of the University Hospital, Botucatu School of Medicine, UNESP, Brazil were included, evaluated primarily by the colonization (cultures collected from the nose and pericatheter skin, at three different times during 12 months) and subsequently were observed regarding the risk for the occurrence of infections, followed by at least 36 months confirmed with cultures from peritoneal effluent in the occurrence of peritonitis and secretion of the pericatheter skin in the occurrence of infection in the outlet orifice of the catheter...


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged, 80 and over , Peritoneal Dialysis/adverse effects , Peritonitis/diagnosis , Staphylococcus aureus/isolation & purification , Staphylococcus aureus/pathogenicity
19.
Esculapio. 2013; 9 (2): 62-65
in English | IMEMR (Eastern Mediterranean) | ID: emr-142826

ABSTRACT

The objective of this study was to evaluate the accuracy of reagent strips for diagnosis of spontaneous bacterial peritonitis [SBP] in cirrhotic patients with ascites, taking polymorphonuclear cell count in ascetic fluid as standard criterion. One hundred and fifty patients having cirrhosis of liver and suspicion of SBP admitted in the medical ward of Services Hospital, Lahore were included in the study. Ascetic fluid of the patients was tested in the hospital laboratory for polymorph nuclear cell count and at the same time leukocyte esterase activity of the fluid was assessed by reagent strips. The sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of reagent strips were calculated. Frequency of SBP in cirrhotic patients with ascites was 28.67%. Specificity, sensitivity, positive predictive value, negative predictive value and diagnostic accuracy of reagent strips for diagnosis of SBP in cirrhotic patients with ascites, taking PMN cell count in ascetic fluid as standard criterion was calculated as 93.02%, 94.39%,86.97%,97.12% and 94% respectively. In view of the results of the current study reagent strip method can be recommended as a rapid and accurate method for diagnosis of SBP in cirrhotic patients


Subject(s)
Humans , Male , Female , Peritonitis/diagnosis , Liver Cirrhosis/complications , Leukocyte Count , Leukocyte Elastase , Peritonitis/etiology , Peritonitis/microbiology , Predictive Value of Tests , Cross-Sectional Studies , Sensitivity and Specificity , Reproducibility of Results
20.
Pakistan Journal of Medical Sciences. 2013; 29 (4): 1028-1032
in English | IMEMR (Eastern Mediterranean) | ID: emr-130369

ABSTRACT

Laparoscopy has gained clinical acceptance in many subspecialties in the last decade. The conventional open surgery for peritonitis carries significant morbidity and mortality. The present study was done to extend and evaluate benefits of minimally invasive surgery in this subset of patients. This was a prospective study spanning over a period of four years. All those patients diagnosed as having peritonitis on clinical assessment and preoperative investigations and those who were stable enough haemodynamically were included in this study. After initial resuscitation for few hours, they underwent diagnostic and therapeutic laparoscopy to identify the cause of peritonitis and to confirm the pathology. All cases were done under general anesthesia, using three standard ports at appropriate sites according to pathology. Patients were treated by different procedures either laparoscopically or with laparoscopic assistance after diagnosis. Operative and post operative data was collected and analyzed. Ninety two cases of peritonitis underwent diagnostic and therapeutic laparoscopy. Mean age of patient was 46.5 years. 24 patients were diagnosed as perforated duodenal, in 14 [58.3%] patients laparoscopic suture repair was done and in 8 [33.3%] small upper midline incision was given and perforation was repaired. Out of 32 patients having perforated appendix, 25 [78.1%] patients laparoscopic appendectomy was done while in 7 [21.8%] perforation was dealt by laparoscopic assistance. Out of 14 patients of ileal perforation 6 [42.8%] with minimal contamination laparoscopic suture was applied, while in 8 [57.1%], perforated loop was brought out by making small window and perforation was closed. All 22 patients with pelvic sepsis needed only aspiration of pus and peritoneal lavage. Only one patient died post operatively and 2 [2.1%] patients developed fistula. 6 [6.5%] patients developed port site infection. Laparoscopic management is feasible, safe and effective surgical option for patients with peritonitis due to different abdominal emergencies in properly selected cases with higher diagnostic yield and a faster postoperative recovery


Subject(s)
Humans , Female , Male , Laparoscopy , Prospective Studies , Peritonitis/diagnosis , Disease Management
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