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1.
Rev. cuba. cir ; 59(2): e957, abr.-jun. 2020.
Article in Spanish | LILACS, CUMED | ID: biblio-1126419

ABSTRACT

RESUMEN La pandemia actual COVID-19 ha afectado la población mundial con cifras alarmantes de contaminados y fallecidos, con un agotamiento de los recursos logísticos de los sistemas de salud. No serán pocos los pacientes sospechosos o confirmados de esta enfermedad que necesitarán tratamiento quirúrgico impostergable. El objetivo del estudio es exponer un conjunto de medidas para garantizar la mejor atención de estos pacientes, reducir la posibilidad de contagio entre pacientes, del personal sanitario y el desarrollo de complicaciones postoperatorias. Se realizó una revisión de la literatura actualizada sobre el tema en formato digital, en publicaciones en idioma inglés y español. La reorganización de los servicios quirúrgicos es necesaria para garantizar la mejor atención a los pacientes, salvaguardar al personal sanitario y utilizar adecuadamente los recursos del sistema de salud(AU)


ABSTRACT The current COVID-19 pandemic has affected the world population with alarming numbers of contaminated and fatalities, with a depletion of the logistical resources of health systems. There will be few suspected or confirmed patients of this disease who will need urgent surgical treatment. The objective of the study is to present a set of measures to guarantee the best care of these patients, reduce the possibility of contagion between patients, health personnel and the development of postoperative complications. A review of the updated literature on the subject was carried out in digital format, in publications in English and Spanish. The reorganization of surgical services is necessary to guarantee the best care for patients, safeguard health personnel, and use the resources of the health system properly(AU)


Subject(s)
Humans , Health Personnel/standards , Coronavirus Infections/diagnosis , Abdomen, Acute/surgery , Postoperative Complications/prevention & control , Review Literature as Topic , Databases, Bibliographic
2.
Int. j. morphol ; 38(3): 552-557, June 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1098286

ABSTRACT

La colecistectomía laparoscópica es el tratamiento de elección de la colelitiasis; sin embargo, se acompaña de comorbilidades y no está exenta de complicaciones mayores que pueden ser letales; la identificación del trígono cistohepático con disección y ligadura de la arteria cística son pasos obligatorios de la cirugía; la identificación de las variaciones de la arteria cística y los conductos biliares pueden minimizar las eventuales complicaciones. Al protocolo preoperatorio se implementó una angiotomografía con Tomógrafo Siemens Somatón Sensation ® de 64 cortes para identificar la arteria cística en pacientes con colelitiasis de la Unidad de Cirugía General del Hospital de Especialidades Teodoro Maldonado Carbo IESS de Guayaquil. Se escogieron 60 pacientes femeninos en forma aleatoria (edades 19-70 años, promedio 44,25 años) y la muestra se dividió en dos grupos de 30; al grupo estudio se aplicó angiotomografía hasta un mes antes de la cirugía y al grupo control se le aplicó el protocolo convencional. Se evaluó morbilidades relacionadas con: hemorragia operatoria por lesión de la arteria cística y en el posoperatorio: infección de herida operatoria, íleo y drenaje. La angiotomografía permitió identificar la arteria cística en el preoperatorio y contribuyó a disminuir comorbilidades que acompañan a la colecistectomía laparoscópica.


Laparoscopic cholecystectomy is the treatment of cholelithiasis of choice; however, it is accompanied by comorbidities and is not exempt from major complications that can be lethal; the identification of the cystohepatic trigone with dissection and ligation of the cystic artery are mandatory steps of surgery; the identification of the variations of the cystic artery and the bile ducts can minimize the possible complications. The preoperative protocol was implemented with an angiotomography with Siemens Somatón Sensation ® 64-slice Tomograph to identify the cystic artery in patients with cholelithiasis of the General Surgery Unit of the Teodoro Maldonado Carbo IESS Specialty Hospital of Guayaquil. 60 female patients were chosen at random (ages 19 -70 years, average 44.25 years) and the sample was divided into two groups of 30; Angiotomography was applied to the study group up to one month before surgery and the conventional protocol was applied to the control group. Morbidities related to: operative haemorrhage due to cystic artery and postoperative injury: operative wound infection, ileus and drainage were evaluated. Angiotomography allowed to identify the cystic artery in the preoperative period and contributed to decrease comorbidities that accompany laparoscopic cholecystectomy.


Subject(s)
Humans , Female , Adult , Middle Aged , Aged , Young Adult , Cholelithiasis/surgery , Celiac Artery/diagnostic imaging , Computed Tomography Angiography/methods , Postoperative Complications/prevention & control , Preoperative Care , Cholelithiasis/diagnostic imaging , Comorbidity , Celiac Artery/anatomy & histology , Cholecystectomy, Laparoscopic
3.
Rev. Hosp. Ital. B. Aires (2004) ; 40(1): 4-10, mar. 2020. ilus, tab
Article in Spanish | LILACS | ID: biblio-1100756

ABSTRACT

Se realizó un estudio prospectivo y descriptivo, incluyendo 103 pacientes que fueron tratados por cáncer de laringe en etapa inicial (T1-T2) con cirugía transoral. De ellos, 55 se diagnosticaron en estadio T1, 16 en estadio T1-b y 32 en estadio T2. El control local inicial (CLI) en pacientes con tumores malignos de laringe estadificados T1 fue 91%, el control local con rescate (CLR) 96%, la preservación de la función de la laringe (PFL) 93% y la sobrevida específica 96%. En T1-b, el CLI fue 81%, el CLR 94%, la PFL 94% y la sobrevida específica 94%. En T2, el CLI fue 63%, el CLR 94%, la PFL 72% y la sobrevida específica 78%. La cirugía transoral en cáncer de laringe con T inicial tiene resultados oncológicos similares a otros tratamientos (cirugía externa o radioterapia), pero consideramos que es la mejor opción por su baja morbilidad, menor duración del tratamiento, y porque deja abiertas todas las posibilidades para tratar posibles recurrencias. (AU)


A prospective and descriptive study was conducted, including 103 patients who were treated for early stage laryngeal cancer (T1-T2) with transoral surgery. Of these, 55 were diagnosed in stage T1, 16 in stage T1-b and 32 in stage T2. The initial local control (CLI) in patients with malignant T1 laryngeal tumors was: 91%, local control with rescue (CLR) 96%, preservation of larynx function (PFL) 93% and specific survival 96%. In T1-b the CLI was 81%, the CLR 94%, the PFL 94% and the specific survival 94%. In T2 the CLI was 63%, the CLR 94%, the PFL 72% and the specific survival 78%. Transoral surgery in laryngeal cancer with initial T has oncological results similar to other treatments (external surgery or radiotherapy), but we consider that it is the best option because of its low morbidity, shorter duration of treatment, and because it leaves open all the possibilities to treat possible recurrences. (AU)


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Laryngeal Neoplasms/surgery , Neoplasm Recurrence, Local/prevention & control , Postoperative Complications/prevention & control , Surgical Procedures, Operative/methods , Vocal Cords/pathology , Voice Quality , Tracheostomy/statistics & numerical data , Laryngeal Neoplasms/classification , Laryngeal Neoplasms/diagnosis , Laryngeal Neoplasms/physiopathology , Laryngeal Neoplasms/mortality , Laryngeal Neoplasms/radiotherapy , Prospective Studies , Epiglottis/pathology , Duration of Therapy , Intubation, Gastrointestinal/statistics & numerical data
4.
Rev. cir. (Impr.) ; 72(1): 30-35, feb. 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1092887

ABSTRACT

Resumen Introducción Los Programas de Recuperación Mejorada (PRM) en cirugía colorrectal disminuyen las complicaciones y acortan la estadía hospitalaria. La implementación de un PRM representa un desafío en nuestro sistema de salud público, dado la alta demanda y recursos limitados. Objetivo Evaluar el efecto en la estadía hospitalaria (EH) posterior a la implementación de un PRM en cirugía colorrectal electiva en un hospital público. Materiales y Método Estudio retrospectivo, que incluyó pacientes entre 15 y 85 años operados electivamente de resecciones colorrectales en un hospital público entre 1 de enero de 2015 y 31 de diciembre de 2016. Se compararon dos grupos: 1) total de pacientes operados electivamente 1 año posterior a la implementación del PRM (post-PRM) y 2) total de pacientes operados electivamente un año previo a la implementación de PRM (pre-PRM), en términos de EH, reingresos, complicaciones y mortalidad a 30 días. Se realizó análisis de tiempo a evento para comparar la EH entre ambos grupos. Resultados Un total de 144 pacientes fueron incluidos: 92 en el grupo post-PRM y 52 en el grupo pre-PRM. No hubo diferencias clínicas entre ambos grupos. La mediana de EH en el grupo post-PRM fue 2 días menor que en el grupo control (5 vs 7 días, test de log-rank, p = 0,03). No hubo diferencia en complicaciones, reingresos ni mortalidad. Conclusión La implementación de un PRM en cirugía colorrectal electiva en un hospital público se asocia a una disminución de la EH sin aumento de morbimortalidad.


Background Enhanced Recovery Programs (ERP) in colorectal surgery has proved to decrease complications and shorten hospital stay. The implementation of an ERP could be a difficult task in a high-demanding public health system with limited resources. Aim Evaluate the effect on length of stay (LOS) after the implantation of an ERP for colorectal surgery in a resource-limited public hospital. Materials and Method This retrospective study included patients aged 15-85 years who underwent elective colorectal surgery at a resource-limited public hospital in Chile between January 1, 2015 and December 31, 2016. We compared two groups: (1) total number of patients operated electively after 1-year of ERP implementation (post-ERP group) and (2) total number of patients electively operated 1-year previous ERP (pre-ERP group) in terms of LOS, readmissions, complications, and 30-day mortality. A time to event analysis was performed to evaluate differences in LOS. Results A total of 144 patients were included in this study: 92 in the post-ERP group and 52 in the pre-ERP group. There were no clinical differences between groups. The median LOS in the post-ERP group was 2 days lower than that in the control group (5 vs 7 days, log-rank test p = 0.03). There were no differences in complications, readmissions, and 30-day mortality. Conclusions The implementation of an ERP for colorectal surgery in a resource-limited hospital was associated with decreased LOS without increasing morbidity.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Program Evaluation , Colonoscopy/rehabilitation , Length of Stay , Postoperative Complications/prevention & control , Colorectal Neoplasms/surgery , Colonoscopy/methods , Perioperative Care/methods , Recovery of Function
5.
Rev Rene (Online) ; 21: 43167, 2020. tab
Article in English, Portuguese | LILACS, BDENF | ID: biblio-1087328

ABSTRACT

Objetivo: identificar a realização de atividades congruentes com os padrões de qualidade dos cuidados de enfermagem por enfermeiros especialistas em enfermagem médico-cirúrgica, no contexto hospitalar. Métodos: estudo descritivo, concretizado em 36 hospitais, no qual participaram 259 enfermeiros especialistas em enfermagem médico-cirúrgica. Para coleta de dados, usou-se de questionário, posteriormente analisado por meio de estatística descritiva. Resultados: os enfermeiros participantes avaliaram com melhores escores as atividades relativas às dimensões responsabilidade e rigor, satisfação do cliente e prevenção de complicações; e com menores escores, as atividades integradas nas dimensões promoção da saúde, readaptação funcional e bem-estar e autocuidado. Conclusão: embora os achados evidenciem atuação dos enfermeiros especialistas na área de enfermagem médico-cirúrgica que tende a ser coerente com os padrões de qualidade, sinalizaram-se lacunas no exercício profissional e potencialidades que podem subsidiar o processo de qualificação desses profissionais, alertar os gestores e qualificar a assistência de enfermagem. (


Objective: to identify the performance of activities con-gruent with the quality standards of nursing care by expert nurses in medical-surgical nursing, in the hospital context. Methods: a descriptive study, carried out in 36 hospitals, in which 259 nurses specialized in medical-surgical nursing participated. For data collection, a questionnaire was used, later analyzed using descriptive statistics. Results: the par-ticipating nurses evaluated activities related to the dimen-sions of responsibility and rigor, customer satisfaction and prevention of complications with better scores; and with lo-wer scores, activities integrated in the dimensions of health promotion, functional readaptation and well-being and self--care. Conclusion: although the findings show the perfor-mance of expert nurses in the medical-surgical nursing area that tends to be consistent with quality standards, gaps in professional practice and potentialities that can support the qualification process of these professionals were signaled, alert managers and qualify nursing care


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Quality Assurance, Health Care , Medical-Surgical Nursing , Hospitals , Nursing Care , Portugal , Postoperative Complications/prevention & control , Self Care , Patient Satisfaction , Health Promotion , Intraoperative Complications/prevention & control
6.
Cuenca; s.n; Universidad de Cuenca; 2020. 41 p. ilus; tab. CD-ROM.
Thesis in Spanish | LILACS | ID: biblio-1102646

ABSTRACT

Abstract: Background: hernia is one of the most frequent pathologies in General Surgery, a common reason for surgical consultation, the resolution of this pathology currently has extensive debates about the surgical approach related to open or laparoscopic hernioplasty, with advantages and disadvantages exposed to each. Objective: to determine the prevalence and factors associated with complications of inguinal posthernioplasty at the Vicente Corral Moscoso and José Carrasco Arteaga Hospitals, 2018-2019.Material and methods: It's analytical, cross-sectional study. 240 clinical records that met the inclusion criteria were reviewed. Data were collected using a form and were tabulated in the SPSS version 15 program. The qualitative variables were analyzed with frequency and percentage and the quantitative variables with arithmetic mean and standard deviation, the associated factors were analyzed with Odds Ratio, 95% CI, Chi square and binary logistic regression (p <0.05).Results: 240 patients who had the inclusion criteria were analyzed, the majority were men (81.7%), the mean age was 53.4 years SD ± 16.57. The prevalence of postoperative complications was 27.5%, with those occurring within the first 24 hours being more frequent with 15.8%. Among the factors associated with statistical significance were: male sex (OR 4.6; 95% CI 1.5-13.5; p <0.00) and surgical technique (OR 3.4; 95% CI 1.2-9; p <0.01).Conclusions: prevalence of postoperative complications was similar to the literature consulted and was associated with factors such as: male sex and surgical technique.


Subject(s)
Humans , Female , Middle Aged , Herniorrhaphy/instrumentation , Hernia, Inguinal/diagnosis , Postoperative Complications/prevention & control , Contraindications, Procedure
7.
Rev. méd. Minas Gerais ; 30: e-3012, 2020.
Article in Portuguese | LILACS | ID: biblio-1118030

ABSTRACT

Introdução: A prática do jejum pré-operatório se consolidou no século XX e prosseguiu praticamente inalterada até os anos 80, onde passou a ser reestruturada. Diante disso, o presente artigo tem o intuito de realizar uma revisão sobre o jejum pré operatório orientado na literatura comparando-o com o que é encontrado dentro da realidade brasileira. Metodologia: Trata-se de um estudo de revisão da literatura, de natureza exploratória, realizada por meio de pesquisa de artigos científicos, dissertações e teses disponíveis nas bases de dados online. Resultados: a American Society of Anesthesiologists desenvolveu a Task "Force on Preoperative Fasting" que estabelece para líquidos claros um jejum mínimo de 2 horas e para dieta leve de 6 horas. No Brasil, um estudo com 3.175 pacientes revelou que 46% deles jejuaram por um período superior a 12 horas. Discussão: Além de não aumentar a possibilidade de danos, observa-se que a redução do tempo de jejum pré-operatório está associada a benefícios no processo de recuperação do paciente. Dentre as causas para o jejum prolongado nas instituições de saúde do Brasil estão o atraso nas operações, a transferência de horário e de período ou o seu adiamento para o próximo dia. Conclusão: o aprimoramento do jejum pré-operatório é necessário, tendo como estratégia a melhor comunicação entre equipes médicas e de enfermagem e o paciente atendido nas instituições hospitalares. (AU)


Background: The practice of preoperative fasting was consolidated in the twentieth century and remained unchanged until the 1980s, when it was questioned. Therefore, the present article aims to review the preoperative fasting oriented in the literature comparing it with what is found in Brazilian reality. Methods: This is an exploratory literature review study, conducted through research of scientific articles, dissertations and theses available in online databases. Results: The American Society of Anesthesiologists has developed the Task Force on Preoperative Fasting, which establishes for clear liquids a minimum fasting of 2 hours and 6 hours for a light diet. In Brazil, a study with 3,175 patients revealed that 46% of them fasted for more than 12 hours. Discussion: In addition to not increasing the possibility of damage, it is observed that the reduction of preoperative fasting time is associated with benefits in patient's recovery process. Causes of prolonged fasting in Brazilian health institutions include delayed operations, changes on time and period, or postponement to the next day. Conclusions: the improvement of preoperative fasting is necessary, having as strategy a better communication between medical and nursing teams and the patients treated at hospitals. (AU)


Subject(s)
Humans , Fasting , Preoperative Period , Physician-Patient Relations , Postoperative Complications/prevention & control , Time Factors , Intraoperative Complications/prevention & control , Nurse-Patient Relations
8.
Rev. Pesqui. (Univ. Fed. Estado Rio J., Online) ; 12: 971-976, jan.-dez. 2020. graf, tab
Article in English, Portuguese | LILACS, BDENF | ID: biblio-1119071

ABSTRACT

Objetivos: Identificar os fatores de risco pré e pós-operatórios relacionados ao desenvolvimento de mediastinite entre pacientes submetidos à cirurgia cardíaca em um hospital da cidade do Rio de Janeiro, caracterizar a população estudada e analisar a relação entre os fatores de risco e a incidência de mediastinite nos pacientes submetidos à cirurgia cardíaca. Método: Estudo descritivo, abordagem quantitativa, em que foram identificados os fatores de risco para mediastinite em pacientes que realizaram cirurgia cardíaca em um hospital do Rio de Janeiro. Resultados: Obteve-se um n de 192 pacientes, de maioria homens, na faixa etária de 50 a 69 anos e em sobrepeso. Diabetes mellitus e tabagismo foram as comorbidades mais frequentes, e CRVMC a cirurgia mais realizada, 4 pacientes apresentaram mediastinite. Conclusão: A identificação destes fatores contribui para elaboração de estratégias de prevenção para mediastinite, e na implementação de cuidados de enfermagem no pré e pós-operatório de cirurgias cardíacas


Objectives: To identify pre and postoperative risk factors related to the development of mediastinitis among patients submitted to cardiac surgery at a hospital in the city of Rio de Janeiro, to characterize the study population and to analyze the relationship between risk factors and the incidence of mediastinitis in patients undergoing cardiac surgery. Method: descriptive study, quantitative approach, in which the risk factors for mediastinitis were identified in patients who underwent cardiac surgery in a hospital in Rio de Janeiro. Results: a n of 192 patients, mostly males, aged 50 to 69 years and overweight were obtained. Diabetes mellitus and smoking were the most frequent comorbidities, and CRVMC the most performed surgery, 4 patients had mediastinitis. Conclusion: the identification of these factors contributes to the elaboration of prevention strategies for mediastinitis, and the implementation of nursing care in the pre and postoperative period of cardiac surgeries


Objetivos: Identificar los factores de riesgo pre y postoperatorios relacionados al desarrollo de mediastinitis entre pacientes sometidos a la cirugía cardiaca en un hospital de la ciudad de Río de Janeiro, caracterizar a la población estudiada y analizar la relación entre los factores de riesgo y la incidencia de mediastinitis en los pacientes sometidos a la cirugía cardiaca. Método: Estudio descriptivo, abordaje cuantitativo, en que se identificaron los factores de riesgo para la mediastinitis en pacientes que realizaron una intervención cardiaca en un hospital de Río de Janeiro. Resultados: Se obtuvo un n de 192 pacientes, de mayoría hombres, en el grupo de edad de 50 a 69 años y en sobrepeso. La diabetes mellitus y el tabaquismo fueron las comorbilidades más frecuentes, y CRVMC la cirugía más realizada, 4 pacientes presentaron mediastinitis. Conclusión: La identificación de estos factores contribuye a la elaboración de estrategias de prevención para la mediastinitis, y en la implementación de cuidados de enfermería en el pre y postoperatorio de cirugías cardíacas


Subject(s)
Humans , Male , Female , Child , Adolescent , Adult , Middle Aged , Aged , Postoperative Complications/prevention & control , Thoracic Surgery/statistics & numerical data , Mediastinitis/epidemiology , Postoperative Complications/epidemiology , Surgical Wound Infection/complications , Retrospective Studies , Risk Factors , Mediastinitis/complications
9.
Rev. enferm. UERJ ; 27: e45758, jan.-dez. 2019. ilus
Article in Portuguese | LILACS, BDENF | ID: biblio-1099963

ABSTRACT

Objetivo: identificar e analisar as evidências disponíveis na literatura sobre as complicações de estomia intestinal e pele periestoma. Método: revisão integrativa, em bases virtuais de dados, com inclusão de estudos do tipo ensaio clínico randomizado, publicados nos idiomas inglês, espanhol e português, no período de maio 2013 a maio de 2019. Resultados: foram selecionados 19 estudos e agrupados em três categorias: técnicas cirúrgicas apontando técnicas inovadoras acerca do tipo de suturas, ressecção e exteriorização de alça intestinal, além de reforços para prevenção de hérnias; barreiras de pele e equipamentos coletores, abordando principalmente as barreiras de pele para prevenção e tratamento da dermatite; cuidados de enfermagem mostrando cuidados e programas de acompanhamento, como visitas domiciliares, consultas e programas educativos. Conclusões: As estratégias descritas nos estudos revisados são importantes na medida em que poderão enriquecer o conhecimento do enfermeiro e dessa forma reduzir complicações de estomia e pele periestoma e melhorar a qualidade de vida dessas pessoas.


Objective: to identify and analyze the evidence available in the literature on the complications of intestinal ostomy and peristomal skin. Method: integrative review in virtual databases, including randomized clinical trialstudies published in English, Spanish and Portuguese, from May 2013 to May 2019. Results: 19 studies were selected and grouped into three categories: surgical techniques pointing innovative techniques about the type of sutures, resection and externalization of the intestinal loop, in addition to reinforcements to prevent hernias; skin barriers and collecting equipment, mainly addressing skin barriers for the prevention and treatment of dermatitis; nursing care showing care and follow-up programs such as home visits, consultations, and educational programs. Conclusion: the strategies described in the reviewed studies are important as they may enrich the knowledge of nurses and thus reduce complications of ostomy and peristome skin and improve the quality of life of these people.


Objetivo: identificar y analizar la evidencia disponible en la literatura sobre las complicaciones de la ostomía intestinal y la piel peristomal. Método: revisión integradora en bases de datos virtuales, incluidos estudios de ensayos clínicos aleatorizados publicados en inglés, español y portugués, de mayo de 2013 a mayo de 2019. Resultados: se seleccionaron 19 estudios y se agruparon en tres categorías: técnicas quirúrgicas que apuntan técnicas innovadoras sobre el tipo de suturas, resección y externalización del asa intestinal, además de refuerzos para prevenir hernias; barreras cutáneas y equipos de recolección, principalmente para abordar las barreras cutáneas para la prevención y el tratamiento de la dermatitis; atención de enfermería que muestra programas de atención y seguimiento, como visitas domiciliarias, consultas y programas educativos. Conclusiones: Las estrategias descritas en los estudios revisados on importantes ya que pueden enriquecer el conocimiento de las enfermeras y, por lo tanto, reducir las complicaciones de la ostomía y la piel peristómica y mejorar la calidad de vida de estas personas.


Subject(s)
Humans , Adult , Enterostomy/adverse effects , Enterostomy/nursing , Dermatitis/nursing , Evidence-Based Nursing , Postoperative Complications/nursing , Postoperative Complications/prevention & control , Quality of Life , Dermatitis/prevention & control
11.
Acta cir. bras ; 34(10): e201901002, Oct. 2019. tab, graf
Article in English | LILACS | ID: biblio-1054669

ABSTRACT

Abstract Purpose: To evaluate the effect of garlic on formation of postoperative adhesions in rats. Methods: Twenty-four Sprague dawley rats were divided into three groups. In Group 1 (sham), laparotomy was performed and stitched up. In Group 2 (control), after laparotomy was performed, punctate hemorrhage was induced by cecal abrasion in the cecum and 2 cc of saline was intraperitoneally administered to each rat. In Group 3 (experimental), after laparotomy was performed, punctate hemorrhage was induced by cecal abrasion in the cecum and each rat was intraperitoneally administered a sterile Allium sativum derivative. The rats in all groups were re-laparotomized on postoperative day 7; samples were obtained from the peritoneal tissue surrounding the cecum Results: In Group 3, there was a statistically significant difference in terms of inflammation, lymph node size, and free oxygen radicals; these parameters tended to increase. In terms of fibrosis evaluated using H&E and MT, there was no significant difference between groups 2 and 3. Conclusions: No positive outcomes indicating that Allium sativum reduces intra-abdominal adhesions were obtained. However, it caused severe inflammation in the tissue. Additionally, in immunohistochemical analyses conducted to detect oxidative stress, allium sativum increased the production of free oxygen radicals in the tissue.


Subject(s)
Animals , Peritoneal Diseases/prevention & control , Garlic/chemistry , Peritoneal Diseases/pathology , Postoperative Complications/pathology , Postoperative Complications/prevention & control , Fibrosis , Immunohistochemistry , Tissue Adhesions/pathology , Tissue Adhesions/prevention & control , Reproducibility of Results , Rats, Sprague-Dawley , Oxidative Stress/drug effects , Free Radicals/analysis , Laparotomy , Lymph Nodes/drug effects , Lymph Nodes/pathology
12.
Rev. ADM ; 76(5): 267-271, sept.-oct. 2019. ilus, tab
Article in Spanish | LILACS | ID: biblio-1053026

ABSTRACT

Introducción: La odontectomía del tercer molar produce una respuesta metabólica al trauma quirúrgico caracterizada por una importante infl amación del área, por lo que para su control se cuenta con diferentes opciones terapéuticas como la farmacoterapia, crioterapia y laserterapia, así como otras alternativas como la compresión de la región, cuya propuesta presentada en este trabajo es a través de la utilización de un apósito adhesivo facial. Objetivo: Evaluar la efi cacia de la aplicación de un apósito adhesivo facial para el control de la infl amación postquirúrgica de la odontectomía del tercer molar. Material y métodos: Se realizó un ensayo clínico controlado de fase I multicéntrico. Se conformó un grupo de estudio experimental y de control con 10 participantes en cada uno, de ambos sexos, de 18-30 años de edad, sanos y que presentaron un tercer molar inferior izquierdo retenido vertical o mesioangular, clase I o II, posición A o B (Pell y Gregory). Se efectuaron las odontectomías bajo anestesia local y sólo en el grupo experimental se utilizó un apósito adhesivo transparente marca Tegaderm® de 3M, el cual se colocó sobre la mejilla de los pacientes durante 48 horas. La evaluación de la infl amación se realizó con el método de Laskin modifi cado previo al procedimiento, a las 48 horas y en el quinto día postoperatorio. Resultados: El promedio de la longitud de la línea 1 a las 48 horas y al quinto día postoperatorio en el grupo experimental fue menor que en el grupo control siendo las diferencias estadísticamente signifi cativas. En el resto de las líneas, la longitud promedio también fue menor en el grupo experimental; sin embargo, no se encontraron diferencias estadísticamente signifi cativas. Conclusión: Este ensayo clínico no es concluyente respecto a la efi cacia del apósito adherible facial para reducir la infl amación postquirúrgica de la odontectomía del tercer molar (AU)


Introduction: The third molar odontectomy produces a metabolic response to surgical trauma characterized by an important infl ammation of the area, so that, for its control, it has diff erent therapeutic options as the pharmacotherapy, cryotherapy and laser therapy, as well as other alternatives such as compression of the region, whose proposal presented in this work is using a facial adhesive dressing. Objective: Evaluate the eff ectiveness of the implementation of a facial adhesive dressing for the control of postsurgical infl ammation of the third molar odontectomy. Material and methods: It has been made a controlled clinical trial of phase I multicentric. It formed a group of experimental and control study with 10 participants in each one, of both sexes, 18- 30 years of age, healthy and that presented a lower left third molar retained vertical or mesioangular, class I or II, position A or B (Pell and Gregory). Odontectomy were performed under local anesthesia and only in the experimental group used a transparent fi lm dressing Tegaderm® by 3M which was placed on the cheek of the patients for 48 hours. The evaluation of the infl ammation was performed with the method of Laskin modifi ed prior to the procedure, at 48 hours and on the 5th postoperative day. Results: The average of the length of the line 1 to 48 hours and at the 5th postoperative day was lower in the experimental group than in the control group, the diff erences being statistically signifi cant. In the rest of the lines, the average length was also lower in the experimental group, however, there were no statistically signifi cant diff erences. Conclusion: This trial is not conclusive as to the eff ectiveness of the dressing stick coating facial to reduce the postsurgical infl ammation of the third molar odontectomy (AU)


Subject(s)
Humans , Male , Female , Adolescent , Adult , Osteotomy , Pain, Postoperative/prevention & control , Bandages , Inflammation/prevention & control , Molar, Third/surgery , Postoperative Complications/prevention & control , Statistical Analysis , Mexico
13.
Braz. j. otorhinolaryngol. (Impr.) ; 85(5): 551-559, Sept.-Oct. 2019. tab, graf
Article in English | LILACS | ID: biblio-1039282

ABSTRACT

Abstract Introduction: Radiologic evaluation is mandatory to assess the type of endoscopic approach concerning sinonasal pathology and reconstruction of fractured defects before any treatment modalities are instituted related to medial wall of the orbit. Objective: The goal was to provide improved understanding of the lamina papyracea variations and the relationship with the orbital morphometry. Methods: This retrospective study was performed using computed tomography scans of 200 orbits and results were compared with respect to age, sex, laterality and LP variations. Results: Lamina papyracea variations were categorized as type A, 80.5% (161/200); type B, 16% (32/200); type C, 3.5% (7/200). For medial wall the anterior and posterior lamina papyracea heights and angles were found as 17.14 mm, 147.88º and 9.6 mm, 152.72º, respectively. Also, the length of the lamina papyracea, the mean area of the orbital floor, medial wall, lamina papyracea and orbital entrance were 33.3 mm, 7.2 cm2, 6.89 cm2, 4.51 cm2 and 12.46 cm2 respectively. The orbital height and width were measured as 35.9 mm and 39.2 mm respectively. The mean orbital cavity depth was 46.3 mm from optic foramen to the orbital entrance and the orbital volume was 19.29 cm3. We analyzed the morphometric measurements tending to increase with aging and greater in men and the relationship of them with lamina papyracea types. Conclusion: Precise knowledge of the lamina papyracea anatomy using computed tomography is essential for safer and more effective surgery and preforming the dimensions of an implant. In this way, the postoperative complications can be decreased and the best outcome can be provided.


Resumo Introdução: A avaliação radiológica é mandatória para avaliar o tipo de abordagem endoscópica no tratamento cirúrgico de doença nasossinusal e na reconstrução de fraturas antes de quaisquer modalidades de tratamento relacionadas à parede medial orbital. Objetivo: O objetivo foi proporcionar uma melhor compreensão das variações da lâmina papirácea e a relação com a morfometria orbital. Método: Este estudo retrospectivo foi realizado por meio de tomografia computadorizada de 200 órbitas, e os resultados foram comparados em relação à idade, sexo, lateralidade e variações da lâmina pairácea. Resultados: As variações da lâmina papirácea foram categorizadas como tipo A, 80,5% (161/200); tipo B, 16% (32/200); tipo C, 3,5% (7/200). Para a parede medial, as medidas das alturas anteriores e posteriores da lâmina papirácea e ângulos foram de 17,14 mm, 147,88º e 9,6 mm, 152,72º, respectivamente. Além disso, as medidas do seu comprimento da, da área média do assoalho orbital, e da parede medial, lâmina papyracea e entrada orbital foram: 33,3 mm, 7,2 cm2, 6,89 cm2, 4,51 cm2 e 12,46 cm2, respectivamente. As medidas da altura e da largura orbitais foram 35,9 mm e 39,2 mm, respectivamente. A profundidade média da cavidade orbital foi de 46,3 mm, do forame óptico até a entrada orbital, e o volume orbital foi de 19,29 cm3. Analisamos as medidas morfométricas com tendência a aumentar com o envelhecimento e nos indivíduos do sexo masculino, e a relação das mesmas com os tipos de lâmina. Conclusões: O conhecimento preciso da anatomia da lâmina papirácea por meio de tomografia computadorizada é essencial para uma cirurgia mais segura e eficaz, além de permitir pré-moldar as dimensões do implante. Assim, as complicações pós-operatórias podem ser minimizadas, obtendo-se melhores resultados.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged , Young Adult , Orbit/anatomy & histology , Orbit/diagnostic imaging , Tomography, X-Ray Computed/methods , Endoscopy/methods , Orbit/injuries , Paranasal Sinuses/surgery , Paranasal Sinuses/injuries , Paranasal Sinuses/diagnostic imaging , Postoperative Complications/prevention & control , Retrospective Studies , Ethmoid Bone/injuries , Ethmoid Bone/diagnostic imaging
14.
Rev. bras. anestesiol ; 69(5): 477-483, Sept.-Oct. 2019. tab, graf
Article in English | LILACS | ID: biblio-1057453

ABSTRACT

Abstract Background and objectives: Dilated cardiomyopathy is a state of progressive enlargement of cardiac chambers mainly left ventricle which leads to decreased cardiac output and ultimately cardiac failure. Although it has multifactorial etiology, it is quite common in patients with end stage renal disease who require renal transplant surgery for their cure. Both conditions go side by side and anesthetic management of such cases poses real challenge to anesthesiologist. Strict monitoring and control of cardiac physiology is of utmost importance besides meticulous fluid management, thus preserving renal blood flow on one hand and preventing cardiac failure on other hand. This is the basis of achieving good outcome of the renal transplant surgery. Methods: This is a retrospective observational study done by analysing electronic database of 31 patients with dilated cardiomyopathy who underwent renal transplant surgery. Data was studied in terms of demographics, duration of renal disease, comorbidities mainly hypertension, cardiac echo graphic findings including ejection fraction, medications and post-operative outcome. Results: Most common perioperative complication in this patient population was hypotension (51.61%) followed by pulmonary complications postoperative mechanical ventilation (12.9%) and pulmonary edema (6.45%). High incidence of hypotension may be a causative factor to increased rate of delayed graft functioning (12.9%) and acute tubular necrosis (2.23%) in these patients. Conclusion: Strict monitoring and control of hemodynamic parameters as well as meticulous fluid therapy is the cornerstone in improving outcome in patients with dilated cardiomyopathy undergoing renal transplant surgery.


Resumo Justificativa e objetivos A cardiomiopatia dilatada é um estado de aumento progressivo das câmaras cardíacas, principalmente do ventrículo esquerdo, que leva à diminuição do débito cardíaco e, por fim, à insuficiência cardíaca. Embora tenha etiologia multifatorial, é bastante comum em pacientes com doença renal terminal que precisam de transplante renal para sua cura. Ambas as condições andam lado a lado e o manejo anestésico de tais casos é um verdadeiro desafio para o anestesiologista. A monitoração e o controle rigoroso da fisiologia cardíaca são de extrema importância, além de um meticuloso manejo dos líquidos, o que por um lado preserva o fluxo sanguíneo renal, por outro previne a insuficiência cardíaca. Essa é a base para alcançar o bom resultado da cirurgia de transplante renal. Métodos Este estudo observacional retrospectivo foi feito mediante a análise de prontuários eletrônicos de 31 pacientes com cardiomiopatia dilatada submetidos à cirurgia de transplante renal. Os dados foram avaliados em termos demográficos, duração da doença renal, comorbidades (principalmente hipertensão), achados ecocardiográficos (inclusive fração de ejeção), medicamentos e resultados no pós-operatório. Resultados A complicação perioperatória mais comum nessa população de pacientes foi hipotensão (51,61%), seguida de complicações pulmonares, como ventilação mecânica pós-operatória (12,9%) e edema pulmonar (6,45%). A alta incidência de hipotensão pode ser um fator causador do aumento da incidência de atraso no funcionamento do enxerto (12,9%) e necrose tubular aguda (2,23%) nesses pacientes. Conclusão A monitoração rigorosa e o controle dos parâmetros hemodinâmicos, bem como a fluidoterapia criteriosa, são a pedra angular na melhoria dos resultados em pacientes com cardiomiopatia dilatada submetidos à cirurgia de transplante renal.


Subject(s)
Humans , Male , Female , Adult , Young Adult , Cardiomyopathy, Dilated/complications , Kidney Transplantation , Anesthesia , Kidney Failure, Chronic/surgery , Kidney Failure, Chronic/complications , Postoperative Complications/prevention & control , Retrospective Studies , Monitoring, Intraoperative
15.
Int. arch. otorhinolaryngol. (Impr.) ; 23(3): 338-342, July-Sept. 2019. tab, graf
Article in English | LILACS | ID: biblio-1040026

ABSTRACT

Abstract Introduction The main modalities of surgical treatment for laryngeal cancer include transoral laser microsurgery (TLM), open preservation surgery, and total laryngectomy (TL). In the elderly, for the presence of comorbidities, the surgical approach more appropriate in many cases remains TL. The use of a stapler for the closure of the esophagus has been introduced to reduce surgical time and postoperative complications such as pharyngocutaneous fistula (PCF). Objective In the present study, we have evaluated the effectiveness of the use of the horizontal mechanical pharyngoesophageal closure in patients who underwent TL. Methods This nonrandomized study was performed on consecutive patients with histopathologically proven squamous cell endolaryngeal carcinoma. The TLwas performed using a linear stapler to mechanically suture the pharyngotomy using the semiclosed technique. Results A total of 33 patients underwent TL, and 13 of themunderwent neck dissection. A total of 15 patients (45.4%) were ≤70 years old, and 18 were > 70 years old. Analyzing the results in relation to age, patients > 70 years old showed tumors at an earlier stage than those aged ≤70 years old. Furthermore, in this group there was a greater number of patients who had comorbidities (p = 0.014). In total, we had 2 (6%) cases of PCF in 6.6% in the group ≤70 years old, and in 5.5% of the group > 70 years old (p = 1.00). Conclusions The use of the stapler for the horizontal closure of the pharyngoesophagectomy in the patients subjected to TL is proven to be useful and safe even when used in elderly patients.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Aged, 80 and over , Carcinoma, Squamous Cell/surgery , Laryngeal Neoplasms/surgery , Laryngectomy/methods , Pharynx/surgery , Postoperative Complications/prevention & control , Surgical Staplers , Suture Techniques/instrumentation , Treatment Outcome , Cutaneous Fistula/prevention & control , Esophagus/surgery
16.
Rev. cir. (Impr.) ; 71(4): 366-372, ago. 2019.
Article in Spanish | LILACS | ID: biblio-1058286

ABSTRACT

Resumen El concepto de Recuperación Mejorada Después de Cirugía, Enhanced recovery after Surgery (ERAS), engloba una serie de protocolos para el manejo perioperatorio optimizado en diversas patologías quirúrgicas. Los objetivos de estos protocolos son: mejorar los resultados quirúrgicos, disminuir las complicaciones, reducir los días de hospitalización, disminuir los costos asociados a la intervención y, finalmente, favorecer una rehabilitación más rápida. Para una correcta aplicación de estos protocolos, se requiere la interacción y el trabajo de un equipo multidisciplinario. En este artículo, se realizará una puesta al día de las intervenciones más importantes de los procesos perioperatorios de la cirugía torácica.


The concept of ERAS includes a series of optimized perioperative management protocols in various surgical pathologies. The objectives of these protocols are: improve surgical results, reduce complications, reduce length of in-hospital stay, reduce the associated health care costs and finally, favor a more rapid rehabilitation. For the correct application of these protocols, the interaction and work of a multidisciplinary team is required. In this article, an update will be made of the most important interventions in the perioperative processes of thoracic surgery.


Subject(s)
Humans , Clinical Protocols , Perioperative Care/methods , Postoperative Complications/prevention & control , Perioperative Care/standards , Perioperative Period
17.
Rev. Paul. Pediatr. (Ed. Port., Online) ; 37(2): 161-165, Apr.-June 2019. tab
Article in English | LILACS | ID: biblio-1013280

ABSTRACT

ABSTRACT Objective: To investigate how symptoms vary according to the appendiceal position in pediatric patients and to demonstrate that the laparoscopic approach is safe and effective in any appendiceal location by comparing each location to another. Methods: The medical records of 1,736 children aged 14 or younger who underwent laparoscopic appendectomy over a period of 14 years were analyzed retrospectively. Patients were divided according to the position of the appendiceal tip into four groups: anterior, pelvic, retrocecal and subhepatic. The Kruskal-Wallis and chi-square tests were used with the Bonferroni correction, with a significant p<0.05. Results: The appendiceal location was anterior in 1,366 cases, retrocecal in 248 cases, pelvic in 66 cases and subhepatic in 56 cases. There were no significant differences between the groups in terms of patient age and gender. Abdominal pain was the only symptom with statistically significant differences between the groups. The rate of perforated appendicitis was higher in the subhepatic and pelvic positions. Intraoperative complications and conversions were not statistically significant. Technical difficulties and operative time were higher in subhepatic position. The rate of postoperative complications was similar between the different locations, except for bowel obstruction, which was higher in pelvic appendicitis. Conclusions: The clinical symptoms of appendicitis hardly ever change with the position of the appendix. The laparoscopic approach is safe and effective, regardless the appendiceal location.


RESUMO Objetivo: Investigar como os sintomas variam de acordo com a posição do apêndice em pacientes pediátricos e demonstrar que a laparoscopia é segura e eficaz em qualquer posição do apêndice, comparando-as. Métodos: Os prontuários de 1.736 pacientes pediátricos com idade ≤14 anos submetidos à apendicectomia laparoscópica em um período de 14 anos foram analisados retrospectivamente. Os pacientes foram divididos de acordo com a posição do apêndice: anterior, pélvica, retrocecal e sub-hepático. Os testes de Kruskal-Wallis e do qui-quadrado foram usados com a correção de Bonferroni, sendo significante p<0,05. Resultados: A posição do apêndice era anterior em 1.366 casos, retrocecal em 248 casos, pélvica em 66 casos e sub-hepática em 56 casos. Não houve diferenças significativas entre os grupos quanto às variáveis idade e sexo. A dor abdominal foi a única variável com diferenças estatisticamente significantes entre os grupos. A taxa de apêndice perfurado foi superior nas posições sub-hepática e pélvica. As complicações intraoperatórias e a taxa de conversão não foram estatisticamente significativas. As dificuldades técnicas e o tempo cirúrgico foram superiores em posição sub-hepática. A taxa de complicações pós-operatórias foi semelhante entre as diferentes posições, exceto a obstrução intestinal, que foi superior em posição pélvica. Conclusões: Os sintomas da apendicite dificilmente variam com a posição do apêndice. A laparoscopia é segura e eficaz, independentemente da posição do apêndice.


Subject(s)
Humans , Male , Female , Child , Adolescent , Appendicitis/surgery , Appendix/pathology , Outcome and Process Assessment, Health Care , Appendectomy/adverse effects , Appendectomy/methods , Appendectomy/statistics & numerical data , Appendicitis/diagnosis , Appendicitis/physiopathology , Appendicitis/epidemiology , Postoperative Complications/etiology , Postoperative Complications/prevention & control , Postoperative Complications/epidemiology , Spain/epidemiology , Abdominal Pain/diagnosis , Abdominal Pain/etiology , Laparoscopy/adverse effects , Laparoscopy/methods , Laparoscopy/statistics & numerical data , Operative Time , Intraoperative Complications/epidemiology
18.
Rev. bras. cir. plást ; 34(1): 23-40, jan.-mar. 2019. ilus, tab, graf
Article in Portuguese | LILACS | ID: biblio-994538

ABSTRACT

Introdução: A necessidade de oferecer resultados com maior definição nas abdominoplastias nos compele a evoluir tecnicamente. O objetivo deste trabalho é apresentar a técnica de plicatura em Crossbow com suas três variantes, reforçando o conceito de aproximação vertical e horizontal da aponeurose dos músculos retos e oblíquos abdominais ao mesmo tempo, promovendo dois vetores diferentes de tração, culminando em uma maior definição da parede abdominal, principalmente na região do hipogastro e fossas ilíacas. Métodos: No período entre janeiro de 2016 e fevereiro de 2018, foram realizadas 22 cirurgias exclusivamente com a técnica Crossbow em seus tipos l, ll e lll, tanto em pacientes estéticos como pós-bariátricos. Resultados: Os resultados foram favoráveis tanto do ponto de vista estético, com maior definição do hipogastro, como do ponto de vista clínico, uma vez que nenhum paciente apresentou sinais ou sintomas diferentes de técnicas convencionais. Conclusão: A técnica Crossbow é simples e reprodutível, sendo mais um agregante na armamentária para melhorar a estética abdominal. Apesar de promover o reforço da região hipogástrica, tanto para tratamento primário como secundário desta região, só o aumento da casuística poderá demonstrar as possíveis vantagens do método.


Introduction: Owing to the need to deliver results with greater definition in abdominoplasties, techniques must evolve. The objective of this study was to introduce the crossbow technique for plication along with its three variants that reinforces the concept of vertical and horizontal alignments of the aponeurosis of the rectus and oblique abdominis muscles at the same time, promotes 2 different traction vectors, and culminates in a greater definition of the abdominal wall, mainly in the hypogastrium and iliac fossa regions. Methods: From January 2016 to February 2018, 22 surgeries were performed exclusively with the types l, ll, or lll crossbow technique, both in esthetic surgery cases and post-bariatric patients. Results: The results were favorable both from the esthetic point of view, with greater definition of the hypogastrium, and from a clinical point of view, as none of the patients showed signs or symptoms different from those of the conventional techniques. Conclusion: The crossbow technique is a simple and reproducible tool in the medical armamentarium to improve abdominal esthetics. Although it promotes the strengthening of the hypogastric region, both for primary and secondary treatments of this region, only a sample size increase can demonstrate the possible advantages of the method.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Postoperative Complications/prevention & control , Abdominal Muscles/surgery , Reconstructive Surgical Procedures/adverse effects , Reconstructive Surgical Procedures/methods , Abdominal Wall/abnormalities , Abdominal Wall/surgery , Aponeurosis/abnormalities , Aponeurosis/surgery
19.
Rev. gaúch. enferm ; 40(spe): e20180218, 2019. tab, graf
Article in Portuguese | LILACS, BDENF | ID: biblio-1004110

ABSTRACT

Resumo OBJETIVO Descrever a implantação do protocolo de termorregulação para procedimentos cirúrgicos em recém-nascido (RN). MÉTODOS Relato de experiência, realizado em uma unidade neonatal em Salvador-BA, no período de janeiro de 2016 a janeiro 2017. O ciclo Plan, Do, Check, Action norteou a construção, a implantação e a aplicabilidade do protocolo. RESULTADOS Implantação do protocolo que possibilitou a redução de eventos adversos por instabilidade térmica durante procedimentos cirúrgicos e introdução de novas tecnologias. CONCLUSÃO O protocolo possibilitou a melhoria e o fortalecimento das práticas assistenciais relacionadas com a cirurgia segura em RN.


Resumen OBJETIVO Describir la implementación del protocolo de termorregulación para procedimientos quirúrgicos en recién nacido (RN). MÉTODOS Relato de experiencia, realizado en una unidad neonatal en Salvador-BA, en el período de enero de 2016 a enero de 2017. El ciclo Plan, Do, Check, Action orientó la construcción, la implementación y la aplicabilidad del protocolo. RESULTADOS Se pudo implementar el protocolo que permitió reducir eventos adversos por inestabilidad térmica durante procedimientos quirúrgicos y se introdujo nuevas tecnologías. CONCLUSIÓN El protocolo permitió una mejora y un fortalecimiento de las prácticas asistenciales, relacionadas con la cirugía segura en RN.


Abstract OBJECTIVE To describe the thermoregulation protocol implementation for newborns (NB). METHODS An experimental report, conducted at a neonatal unit in Salvador, Bahia, from January 2016 to January 2017. The Plan, Do, Check, Action cycle guided the construction, implementation and applicability of the protocol. RESULTS Implementation of the protocol that allowed the reduction of adverse events due to thermal instability during surgical procedures and introduction of new technologies. CONCLUSION The protocol could improve and strengthen the care practices related to safe surgery in newborns.


Subject(s)
Humans , Infant, Newborn , Postoperative Complications/prevention & control , Surgical Procedures, Operative , Clinical Protocols , Perioperative Care/methods , Fever/prevention & control , Hypothermia/prevention & control , Intraoperative Complications/prevention & control , Practice Guidelines as Topic
20.
Acta cir. bras ; 34(1): e20190010000009, 2019. tab, graf
Article in English | LILACS | ID: biblio-983686

ABSTRACT

Abstract Purpose: To evaluate the contribution of ursodeoxycholic acid (UDCA) in the first 12 months after Roux-en-Y gastric bypass in the prevention of gallstone formation. Methods: A community-based clinical trial was conducted. A total of 137 patients were included in the study; 69 were treated with UDCA, starting 30 days after the surgery, at a dose of 150 mg twice daily (300 mg/day) over a period of 5 consecutive months (GROUP A), and 68 were control patients (GROUP B). The patients were followed-up, and ultrasonography was performed to determine the presence of gallstones at various times during follow-up. Demographic, anthropometric and comorbid indicators were obtained. The data were subjected to normality tests and evaluated using appropriate tests. Results: Patients did not differ in their baseline characteristics. Of the 69 patients who used UDCA, only one patient developed cholelithiasis (1%), whereas 18 controls (26%) formed gallstones (OR = 24.4, p <0.001). Also, other factors were found not to influence the formation of calculi, such as pre-operative or postoperative hepatic steatosis or diabetes (p = 0.759, 0.468, 0.956). Conclusion: The results demonstrated that patients who did not use UDCA showed a 24.4-fold greater probability of developing cholelithiasis.


Subject(s)
Humans , Male , Female , Adult , Postoperative Complications/prevention & control , Ursodeoxycholic Acid/therapeutic use , Obesity, Morbid/surgery , Cholagogues and Choleretics/therapeutic use , Gastric Bypass/adverse effects , Gallstones/prevention & control , Postoperative Complications/etiology , Postoperative Complications/drug therapy , Postoperative Period , Stomach/surgery , Gallstones/etiology , Gallstones/drug therapy , Comorbidity , Anthropometry , Prospective Studies
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