ABSTRACT
Abstract Introduction: General anesthesia causes pulmonary atelectasis within few minutes of induction. This can have significant impact on postoperative outcome of cancer patients undergoing prolonged reconstructive surgeries. Objective: The purpose of this study was to evaluate the impact of sonographically detected perioperative atelectasis on the need for postoperative oxygen supplementation, bronchodilator therapy and assisted chest physiotherapy in patients undergoing free flap surgeries for head and neck carcinoma. Methods: Twenty eight head and neck cancer patients underwent bilateral pulmonary ultrasonographic assessments before and after lung surgery. Lung ultrasound scores, serum lactate, and PaO2/FiO2 ratio were measured both at the beginning and at end of the surgery. Patients were scanned in the supine position and the number of single and confluent B lines was noted. These values were correlated with the need for oxygen therapy, requirement of bronchodilators and total weaning time to predict the postoperative outcome. Other factors affecting weaning were also studied. Results: Among twenty eight patients, seven had mean lung ultrasound score of ≥10.5 which correlated with prolonged weaning time (144.56±33.5min vs. 66.7±15.7min; p = 0.005). The change in lung ultrasound score significantly correlated with change in PaO2/FiO2 ratio (r = −0.56, p = 0.03). Elevated total leukocyte count >8200 ΜL and serum lactate >2.1 mmoL/L also predicted prolonged postoperative mechanical ventilation. Conclusion: This preliminary study detected significant levels of perioperative atelectasis using point of care lung ultrasonography in head and neck cancer patients undergoing long duration surgical reconstructions. Higher lung ultrasound scores highlighted the need for frequent bronchodilator nebulizations as well as assisted chest physiotherapy and were associated with delayed weaning. We propose more frequent point of care lung ultrasonographic evaluations and use of recruitment maneuvers to reduce the impact of perioperative pulmonary atelectasis.
Resumo Introdução: A anestesia geral causa atelectasia pulmonar poucos minutos após sua indução. Isso pode ter um impacto significativo no resultado pós-operatório de pacientes com câncer submetidos a cirurgias reconstrutivas prolongadas. Objetivo: Avaliar o impacto das atelectasias perioperatórias detectadas por ultrassonografia na necessidade de suplementação pós-operatória de oxigênio, terapia broncodilatadora e fisioterapia respiratória assistida em pacientes com carcinoma de cabeça e pescoço submetidos a cirurgias com uso de retalho livre. Método: Foram submetidos a avaliações ultrassonográficas pulmonares bilaterais antes e após a cirurgia 28 pacientes com câncer de cabeça e pescoço. Os escores de ultrassonografia pulmonar, lactato sérico, razão PaO2/FiO2 foram medidos no início e no fim da cirurgia. Os pacientes foram avaliados na posição supina e o número de linhas B confluentes e únicas foi observado. Esses valores foram correlacionados com a necessidade de oxigenoterapia, necessidade de broncodilatadores e tempo total de desmame para predizer o resultado pós-operatório. Outros fatores que afetam o desmame também foram estudados. Resultados: Entre os 28 pacientes, sete apresentaram escore médio de ultrassonografia pulmonar ≥ 10,5, que se correlacionou com o tempo de desmame prolongado (144,56 ± 33,5 minutos vs. 66,7 ± 15,7 minutos; p = 0,005). A mudança no escore de ultrassonografia pulmonar correlacionou-se significantemente com a mudança na razão PaO2/FiO2 (r = −0,56, p = 0,03). A contagem total elevada de leucócitos > 8200 uLe o nível de lactato sérico >2,1 mmoL/L também previram ventilação mecânica pós-operatória prolongada. Conclusão: Este estudo preliminar detectou um nível significante de atelectasia perioperatória com ultrassonografia pulmonar no local de atendimento em pacientes com câncer de cabeça e pescoço submetidos a reconstruções cirúrgicas de longa duração. Escores mais altos de ultrassonografia pulmonar enfatizaram a necessidade de nebulizações broncodilatadoras frequentes e fisioterapia respiratória assistida e foram associados a desmame tardio. Propomos avaliações ultrassonográficas pulmonares mais frequentes no local de atendimento e o uso de manobras de recrutamento para reduzir o impacto das atelectasias pulmonares perioperatórias.
Subject(s)
Humans , Pulmonary Atelectasis/etiology , Pulmonary Atelectasis/therapy , Pulmonary Atelectasis/diagnostic imaging , Plastic Surgery Procedures/adverse effects , Free Tissue Flaps , Head and Neck Neoplasms/surgery , Head and Neck Neoplasms/complications , Head and Neck Neoplasms/diagnostic imaging , Postoperative Complications , Bronchodilator Agents , Ultrasonography/adverse effects , Lactates , LungABSTRACT
Abstract Sclerosing mediastinitis (SM), previously named chronic fibrosing mediastinitis, is an inflammatory process that in its end-stage results to sclerosis around the mediastinal structures. SM is quite rare and has been correlated with inflammatory and autoimmune diseases, as well as malignancy. SM may either present in a mild form, with minor symptoms and a benign course or in a more aggressive form with severe pulmonary hypertension and subsequent higher morbidity and mortality. The diagnosis of SM may be difficult and quite challenging, as symptoms depend on the mediastinal structure that is mainly involved; quite often the superior vena cava. However, practically any mediastinal structure may be involved by the fibrotic process, such as the central airways, as well as the pulmonary arteries and veins, leading to obstruction or total occlusion. The latter may be impossible to undergo proper surgical excision of the lesion, and is considered to be a real challenge to the surgeon. We herein report a case of SM that presented with arterial and venous compression. The imaging appearance was that of unilateral pulmonary edema, associated with lung collapse. The case is supplemented by a non-systematic review of the relevant literature.
Subject(s)
Humans , Female , Adult , Pulmonary Edema/etiology , Pulmonary Atelectasis/etiology , Sclerosis/complications , Mediastinitis/complications , Pulmonary Edema/diagnostic imaging , Pulmonary Atelectasis/pathology , Pulmonary Atelectasis/diagnostic imaging , Biopsy , Radiography, Thoracic , Tomography, X-Ray Computed , Constriction, Pathologic/pathology , Constriction, Pathologic/diagnostic imaging , Heart Atria/pathology , Heart Atria/diagnostic imaging , Mediastinitis/pathology , Mediastinitis/diagnostic imagingABSTRACT
RESUMEN En la aspiración por cuerpo extraño en vías respiratoria, los síntomas van desde el paro cardiorrespiratorio, tos de intensidad y características variables como obstrucción bronquial difusa o localizada. Como complicación puede aparecer la neumonía y atelectasias. La atelectasia es el colapso de una parte periférica del pulmón o de todo el pulmón, debido a la obstrucción de la vía aérea en bronquios o bronquiolos. El objetivo de este trabajo es presentar un caso clínico y la importancia de la intervención de Enfermería en una Transicional, de 1 año y 9 meses de edad, sexo femenino. Ingresó en la Unidad de Terapia Intensiva del Hospital Pediátrico Provincial de Matanzas, con diagnóstico de aspiración de cuerpo extraño en vías aéreas. El desarrollo de las habilidades prácticas del enfermero intensivista fomenta el razonamiento crítico en aras de brindar cuidados con calidad y enfoque científico que repercuten en la mejoría de los pacientes (AU).
ABSTRACT This paper´s aim is to present a clinical case and the importance of the nursing interventions in a female transitional patient, aged 1 years and 9 months. She entered the Intensive Care Unit of the Provincial Pediatric Hospital of Matanzas, with a diagnosis of foreign body aspiration in the airways. The development of the intensive care nurses´ practical skills promotes the critical reasoning for the sake of giving qualitative care with a scientific approach striking on the improvement of the patients (AU).
Subject(s)
Humans , Female , Infant , Quality of Health Care , Pulmonary Atelectasis/diagnosis , Morbidity , Airway Obstruction/complications , Intensive Care Units , Nursing Care , Oxygen Inhalation Therapy , Pulmonary Atelectasis/complications , Pulmonary Atelectasis/nursing , Pulmonary Atelectasis/etiology , Pulmonary Atelectasis/therapy , Airway Obstruction/etiology , Airway Obstruction/epidemiology , GaggingABSTRACT
Resumen Objetivo: Determinar la frecuencia, tipo y predictores de complicaciones pleuropulmonares en los primeros 30 días de postoperatorio de pacientes intervenidos de cirugía cardiovascular sin apoyo de circulación extracorpórea. Métodos: Se realizó un estudio de cohorte retrospectivo durante el periodo comprendido del 1 de enero de 2013 al 31 de diciembre 2014. Incluyó a todos los pacientes portadores de cardiopatías congénitas intervenidos de cirugía cardiaca con abordaje esternal o torácico, sin soporte de circulación extracorpórea con ingreso registrado a Unidad de Cuidados Intensivos del Hospital de Pediatría del Centro Médico Nacional Siglo XXI, IMSS. Se cuantificó la frecuencia de eventos de las complicaciones pleuropulmonares y se realizó un análisis multivariado de regresión logística para identificar los factores de riesgo asociados a complicaciones pleuropulmonares, calculándose odds ratio (OR) e intervalos de confianza al 95% (IC 95%). Resultados: Se incluyeron un total de 139 pacientes, en los cuales la frecuencia de complicaciones pleuropulmonares fue del 42.4% (n = 59), y los tipos más frecuentes fueron atelectasia (28 eventos), neumonía asociada a ventilador (24 eventos), neumotórax (20 eventos), pudiéndose encontrar más de una complicación por paciente. Los predictores más significativos de complicaciones pleuropulmonares fueron las cardiopatías congénitas cianógenas (OR = 3.58; IC 95%: 1.10-7.50; p = 0.001), el abordaje por toracotomía (OR = 1.46; IC 95%: 1.18-1.12; p = 0.008) y el evento quirúrgico realizado de urgencia (OR = 3.46; IC 95%: 1.51-7.95; p = 0.002). Conclusiones: La principal complicación pleuropulmonar fue la atelectasia lo cual concuerda con lo reportado en la literatura internacional. Los pacientes que presenten alguno de los predictores identificados en el presente estudio deben ser monitorizados de manera especial para prevenir, detectar y/o tratar oportunamente las complicaciones pleuropulmonares tras cirugía cardiaca.
Abstract Objective: To determine the frequency and type of pleuropulmonary complications and their predictors in the first thirty postoperative days of patients undergoing surgery without cardiopulmonary bypass. Methods: A retrospective cohort study was carried out between January 2013 and December 2014. It included all patients with congenital heart disease who underwent cardiac surgery using a sternal or thoracic approach, without cardiopulmonary bypass with a registered admission to a Neonatal or Paediatric Intensive Care. The frequency of events of pleuropulmonary complications and logistic regression analysis was performed, and the adjusted odds ratio (OR) and confidence intervals at 95% (95% CI) were calculated. Results: A total of 139 patients were included. The frequency of pleuropulmonary complications was 42.4% (N = 59), and the most frequent types were atelectasis (28 events), ventilator-associated pneumonia (24 events), pneumothorax (20 events), with more than one complication per patient occasionally being found. Significant risk factors were cyanogenic congenital heart disease (OR = 3.58, 95% CI: 1.10-7.50, P =.001), thoracotomy approach (OR = 1.46, 95% CI: 1.18-1.12, P = .008), and an emergency surgical event (OR = 3.46, 95% CI: 1.51-7.95, P = .002). Conclusions: The main pleuropulmonary complication was atelectasis, which is consistent with that reported in the international literature. Patients with any of the predictors identified in the present study should be closely monitored in order to prevent, detect and/or treat pleuropulmonary complications in a timely manner after cardiac surgery.
Subject(s)
Humans , Male , Female , Child, Preschool , Child , Pleural Diseases/epidemiology , Postoperative Complications/epidemiology , Cardiac Surgical Procedures/methods , Lung Diseases/epidemiology , Pleural Diseases/etiology , Pleural Diseases/physiopathology , Postoperative Complications/physiopathology , Pulmonary Atelectasis/etiology , Pulmonary Atelectasis/epidemiology , Intensive Care Units, Pediatric , Intensive Care Units, Neonatal , Logistic Models , Retrospective Studies , Cohort Studies , Heart Defects, Congenital/surgery , Lung Diseases/etiology , Lung Diseases/physiopathologyABSTRACT
Abstract Objective: In this study, the efficacy of thoracic ultrasonography during echocardiography was evaluated in newborns. Methods: Sixty newborns who had undergone pediatric cardiac surgery were successively evaluated between March 1, 2015, and September 1, 2015. Patients were evaluated for effusion, pulmonary atelectasis, and pneumothorax by ultrasonography, and results were compared with X-ray findings. Results: Sixty percent (n=42) of the cases were male, the median age was 14 days (2-30 days), and the median body weight was 3.3 kg (2.8-4.5 kg). The median RACHS-1 score was 4 (2-6). Atelectasis was demonstrated in 66% (n=40) of the cases. Five of them were determined solely by X-ray, 10 of them only by ultrasonography, and 25 of them by both ultrasonography and X-ray. Pneumothorax was determined in 20% (n=12) of the cases. Excluding one case determined by both methods, all of the 11 cases were diagnosed by X-ray. Pleural effusion was diagnosed in 26% (n=16) of the cases. Four of the cases were demonstrated solely by ultrasonography, three of them solely by X-ray, and nine of the cases by both methods. Pericardial effusion was demonstrated in 10% (n=6) of the cases. Except for one of the cases determined by both methods, five of the cases were diagnosed by ultrasonography. There was a moderate correlation when all pathologies evaluated together (k=0.51). Conclusion: Thoracic ultrasonography might be a beneficial non-invasive method to evaluate postoperative respiratory problems in newborns who had congenital cardiac surgery.
Subject(s)
Humans , Male , Female , Infant, Newborn , Pleural Effusion/diagnostic imaging , Postoperative Complications/diagnostic imaging , Pulmonary Atelectasis/diagnostic imaging , Cardiac Surgical Procedures/adverse effects , Pulmonary Atelectasis/etiology , Transposition of Great Vessels/surgery , Echocardiography/methods , Radiography, Thoracic/methods , Ultrasonography/methods , Sensitivity and Specificity , Hypoplastic Left Heart Syndrome/surgeryABSTRACT
Se presenta el caso de un paciente masculino de un año de edad, con antecedentes previos de asma bronquial. Refiere la mamá que hacía 11 días el paciente había sufrido una caída, en ese momento se encontraba ingiriendo maní, pasadas unas horas aparece tos seca, la madre consultó al policlínico de su área donde le pusieron tratamiento con prednisona oral por 3 días, con lo cual nota discreta mejoría, sin desaparecer del todo la tos. Al sexto día del evento comenzó a presentar fiebre de 38°C haciendo dos picos al día, los cuales cedían con la administración de Dipirona en tableta. Debido a que los síntomas persistían (tos y fiebre) la madre lleva nuevamente al niño al facultativo, donde le realizaron radiografía de tórax, observando una imagen atelectásica a nivel del pulmón derecho, por lo que deciden remitir al Hospital Juan Manuel Márquez(AU)
The case is presented of a male patient of one year of age, with antecedents of bronchial asthma. His mother referred that 11 days ago the patient had fallen, at the moment when he was consuming peanuts. Some hours later dry cough appears. The mother consulted the area polyclinic, where the patient was prescribed prednisone by oral way for three days, with which she notices some improvement, but cough did not disappear totally. Six days after the event, the patients presented a 100ºF fever with peaks daily, which drifted when dipyrone pills were administered. As long as the symptoms prevailed (cough and fever), the mother takes the child again to the doctors, where he is taken a thorax radiography, which shows an atelectasis image at the right lung level, a reason why he is decided to be referred to Juan Manuel Márquez Hospital(AU)
Subject(s)
Humans , Male , Infant , Pulmonary Atelectasis/etiology , Foreign BodiesABSTRACT
A formação de atelectasias é um dos distúrbios pulmonares responsável pelo maior tempo de internação dos recém-nascidos nas unidades de terapias intensivas e pelo consequente aumento da morbidade. O cateter nasal de alto fluxo tem sido utilizado na faixa etária neonatal, para evitar e/ou expandir áreas pulmonares atelectasiadas, mesmo que até o momento não existam estudos baseados em evidência. Relatamos os casos de dois pacientes do sexo masculino internados por doença neurocirúrgica e abdominal submetidos à ventilação pulmonar mecânica invasiva por 4 e 36 dias, respectivamente. Após a extubação, foram mantidos em oxigenioterapia, quando, então, ambos apresentaram piora clínica e radiológica compatível com atelectasia. Após 24 horas de instalado o cateter nasal de alto fluxo como suporte não invasivo, novos exames radiológicos mostraram a reversão completa da atelectasia. O uso do cateter de alto fluxo mostrou-se eficaz na reversão de atelectasias, podendo ser utilizada como mais uma das terapias ventilatórias não invasivas, evitando, assim, nova intubação.
Atelectasis is a pulmonary disorder that lengthens the hospitalization time of newborns in intensive care units, resulting in increased morbidity among these infants. High-flow nasal cannulae have been used in newborns to prevent atelectasis and/or expand pulmonary regions affected by atelectasis; however, to date, no evidence-based data regarding this approach have been reported. In this paper, we report on the cases of two male newborn patients. The first and second patients described in this report were hospitalized for a neurosurgical procedure and the treatment of abdominal disease, respectively, and were subjected to invasive mechanical ventilation for 4 and 36 days, respectively. After extubation, these patients continued receiving oxygen therapy but experienced clinical and radiological worsening typical of atelectasis. In both cases, by 24 hours after the implantation of an high-flow nasal cannulae to provide noninvasive support, radiological examinations revealed the complete resolution of atelectasis. In these cases, the use of an high-flow nasal cannulae was effective in reversing atelectasis. Thus, this approach may be utilized as a supplemental noninvasive ventilatory therapy to avoid unnecessary intubation.
Subject(s)
Humans , Infant, Newborn , Male , Airway Extubation/methods , Oxygen Inhalation Therapy/methods , Pulmonary Atelectasis/therapy , Respiration, Artificial/methods , Intensive Care Units , Pulmonary Atelectasis/etiologyABSTRACT
OBJETIVOS: Analisar os efeitos da exposição à hiperóxia (100% de oxigênio) sobre a histoarquitetura pulmonar de camundongos neonatos. MÉTODOS: Camundongos neonatos da linhagem Balb/c foram expostos à hiperóxia (GH) (100% de oxigênio) (n = 10) em uma câmara (15 x 20 x 30 cm) por 24 horas, com fluxo de 2 L/min. O grupo controle (GC) (n = 10) foi exposto a normóxia em um mesmo tipo de câmara e pelo mesmo tempo. Após a exposição, os animais foram sacrificados por decapitação, os pulmões foram removidos para análise histológica e processados de acordo com a rotina do laboratório. Cortes de 3 µm de espessura foram corados com hematoxilina e eosina (H&E). A análise morfométrica foi realizada com o objetivo de analisar macrófagos presentes na luz alveolar, densidade de superfície (Sv) de trocas gasosas, densidade de volume (Vv) de parênquima pulmonar e áreas de atelectasias. RESULTADOS: Foi verificada diminuição do número de macrófagos alveolares (MØ) no GH (GH = 0,08±0,01 MØ/mm²; GC = 0,18±0,03 MØ/mm²; p = 0,0475), Sv de troca gasosa no GH (GH = 8,08 ± 0,12 mm² /mm³; GC = 8,65 ± 0,20 mm² /mm³; p = 0,0233), Vv de parênquima pulmonar no GH (GH = 54,7/33,5/83,5 %/mm²; GC = 75/56,7/107,9 %/mm²; p < 0.0001) quando comparado com o GC. Entretanto, houve aumento de áreas de atelectasias no GH (GH = 17,5/11,3/38,4 atelectasia/mm²; GC = 14/6,1/24,4 atelectasia/mm²; p = 0,0166) quando comparado com o GC. CONCLUSÃO: Nossos resultados indicam que a hiperóxia promoveu alterações na histoarquitetura pulmonar, aumentando áreas de atelectasia e hemorragia alveolar difusa.
OBJECTIVES: To analyze the effects of exposure to hyperoxia (100% oxygen) on the lung histoarchitecture of neonatal mice. METHODS: Neonatal Balb/c mice were exposed to hyperoxia (HG) (100% oxygen) (n = 10) in a chamber (15 x 20 x 30 cm) for 24 horas ours with a flow of 2 L/min. The control group (CG) (n = 10) was exposed to normoxia in the same type of chamber and for the same time. After exposure, the animals were euthanized by decapitation; the lungs were removed and processed for histological examination according to the laboratory routine. Three-mm thick sections were stained with hematoxylin and eosin (H&E). The morphometric analysis was performed with in order to analyze the macrophages present in the alveolar lumen, surface density (Sv) of gas exchange, volume density (Vv) of lung parenchyma, and areas of atelectasis. RESULTS: A decrease in the number of alveolar macrophages (MØ) was observed in the HG (HG = 0.08±0.01 MØ/mm², CG = 0.18±0.03 MØ/mm², p = 0.0475), Sv of gas exchange in HG (HG = 8.08±0.12 mm² /mm³, CG = 8.65±0.20 mm² /mm³, p = 0.0233), Vv of lung parenchyma in HG (HG = 54.7/33.5/83.5%/ mm²; CG = 75/56.7/107.9%/mm², p < 0.0001) when compared with the CG. However, there was an increase in areas of atelectasis in HG (HG = 17.5/11.3/38.4 atelectasis/mm², CG = 14/6.1/24.4 atelectasis/mm², p = 0.0166) when compared with the CG. CONCLUSION: The present results indicate that hyperoxia caused alterations in lung histoarchitecture, increasing areas of atelectasis and diffuse alveolar hemorrhage.
Subject(s)
Animals , Mice , Inhalation Exposure/adverse effects , Lung/pathology , Macrophages, Alveolar/pathology , Oxygen/toxicity , Animals, Newborn , Hemorrhage/etiology , Lung/cytology , Lung/metabolism , Mice, Inbred BALB C , Models, Animal , Macrophages, Alveolar/metabolism , Oxygen/administration & dosage , Pulmonary Atelectasis/etiology , Pulmonary Atelectasis/pathology , Random Allocation , Statistics, NonparametricABSTRACT
OBJETIVO: La exposición a humo de leña es factor de riesgo para EPOC. A diferencia de la EPOC por cigarrillo (EPOC-C), para un mismo nivel de obstrucción, en la EPOC por leña (EPOC-L), la DLCO está menos disminuida, sugiriendo menos enfisema. Por tanto, el objetivo de este estudio fue comparar los hallazgos en la TCAR en mujeres con EPOC-L y con EPOC- C. MÉTODOS: Veintidós mujeres con EPOC severa (VEF1/CVF < 70% y VEF1 < 50%) fueron divididas en dos grupos: las expuestas a leña (EPOC-L; n = 12) y las expuestas a cigarrillo (EPOC-C; n = 10). Se compararon los dos grupos con respecto al puntaje de enfisema y el compromiso de la vía aérea en la TCAR, las anormalidades funcionales en la espirometría, la DLCO, los volúmenes pulmonares y la resistencia específica de la vía aérea (sRaw). RESULTADOS: Los dos grupos tuvieron VEF1, sRaw e hiperinflación pulmonar similares. En el grupo EPOC-C, hubo mayor disminución de la DLCO y de la DLCO/VA y mayor puntaje de enfisema. En el grupo EPOC-L, no encontramos enfisema significativo en la TCAR. Los hallazgos principales fueron engrosamiento peribronquial, dilataciones bronquiales y atelectasias subsegmentarias. CONCLUSIONES: En pacientes con EPOC-L severa no hay enfisema en la TCAR. El hallazgo más importante es el compromiso severo de la vía aérea. La disminución de la DLCO y del VA con DLCO/VA normal es probablemente determinada por la obstrucción bronquial severa y la mezcla incompleta del gas inspirado en la maniobra de la respiración única de la prueba de difusión.
OBJECTIVE: Wood smoke exposure is a risk factor for COPD. For a given degree of airway obstruction, the reduction in DLCO is smaller in individuals with wood smoke-related COPD than in those with smoking-related COPD, suggesting that there is less emphysema in the former. The objective of this study was to compare HRCT findings between women with wood smoke-related COPD and women with smoking-related COPD. METHODS: Twenty-two women with severe COPD (FEV1/FVC ratio < 70% and FEV1 < 50%) were divided into two groups: those with wood smoke-related COPD (n = 12) and those with smoking-related COPD (n = 10). The two groups were compared regarding emphysema scores and airway involvement (as determined by HRCT); and functional abnormalities-spirometry results, DLCO, alveolar volume (VA), the DLCO/VA ratio, lung volumes, and specific airway resistance (sRaw). Results: There were no significant differences between the two groups in terms of FEV1, sRaw, or lung hyperinflation. Decreases in DLCO and in the DLCO/VA ratio were greater in the smoking-related COPD group subjects, who also had higher emphysema scores, in comparison with the wood smoke-related COPD group subjects. In the wood smoke-related COPD group, HRCT scans howed no significant emphysema, the main findings being peribronchial thickening, bronchial dilation, and subsegmental atelectasis. CONCLUSIONS: Female patients with severe wood smoke-related COPD do not appear to develop emphysema, although they do show severe airway involvement. The reduction in DLCO and VA, with a normal DLCO/VA ratio, is probably due to severe bronchial obstruction and incomplete mixing of inspired gas during the determination of single-breath DLCO.
Subject(s)
Adult , Female , Humans , Bronchial Diseases , Pulmonary Atelectasis , Pulmonary Diffusing Capacity/physiology , Pulmonary Disease, Chronic Obstructive/physiopathology , Pulmonary Emphysema , Smoke/adverse effects , Smoking/adverse effects , Bronchial Diseases/etiology , Cross-Sectional Studies , Pulmonary Atelectasis/etiology , Pulmonary Disease, Chronic Obstructive/etiology , Pulmonary Disease, Chronic Obstructive , Pulmonary Emphysema/etiology , Spirometry , Tomography, X-Ray Computed , WoodABSTRACT
A 35-year-old male non-smoker, presented with a history of recurrent respiratory tract infections, associated with intermittent haemoptysis and haematemesis since childhood. His vital parameters were normal with pulse oximetry saturation of 97% on room air. On physical examination, clubbing was observed. Chest auscultation revealed tubular type of bronchial breath sounds over the right hemithorax.
Subject(s)
Adult , Bronchial Fistula/complications , Bronchiectasis/complications , Dilatation, Pathologic , Esophageal Achalasia/complications , Esophageal Achalasia/diagnostic imaging , Esophagus/pathology , Humans , Male , Pulmonary Atelectasis/etiology , Recurrence , Tomography, X-Ray ComputedABSTRACT
Pseudomembranous necrotizing bronchial aspergillosis (PNBA) is a rare form of invasive aspergillosis with a very poor prognosis. The symptoms are non-specific, and the necrotizing plugs cause airway obstruction. Atelectasis and respiratory failure can be the initial manifestations. Recently, we treated an immunocompromised patient with PNBA, who presented with a sudden onset of atelectasis and acute respiratory failure. There were no preceding signs except for a mild cough and one febrile episode. Bronchoscopy revealed PNBA, and Aspergillus nidulans was cultured from the bronchial wash.
Subject(s)
Adult , Female , Humans , Immunocompromised Host , Invasive Pulmonary Aspergillosis/complications , Leukemia, Myeloid, Acute/complications , Neutropenia/complications , Pulmonary Atelectasis/etiology , Respiratory Insufficiency/etiologyABSTRACT
INTRODUÇÃO: A aplicação de ventilação por dois níveis de pressão positiva (BiPAP®) associada à fisioterapia respiratória convencional (FRC) no pós-operatório (PO) imediato de cirurgia cardíaca pode contribuir para a diminuição das complicações pulmonares. OBJETIVO: Avaliar a segurança e a adesão da aplicação preventiva do BiPAP® associado a FRC no PO imediato de revascularização do miocárdio. MÉTODOS: Vinte e seis pacientes submetidos a revascularização do miocárdio foram aleatoriamente alocados. O Grupo Controle (GC) foi tratado com FRC, o Grupo BiPAP (GB) foi submetido a 30 minutos de BiPAP®, duas vezes ao dia, associado à FRC. A FRC foi realizada em ambos os grupos, duas vezes ao dia. Todos os pacientes foram avaliados quanto: capacidade vital, permeabilidade das vias aéreas, pressões respiratórias máximas, saturação de oxigênio, frequência cardíaca, frequência respiratória, volume minuto, volume corrente, pressões arteriais sistólica e diastólica. As avaliações foram realizadas durante a internação no pré-operatório, imediatamente após a extubação, e na 24ª e 48ª horas após extubação. RESULTADOS: No GC, 61,5 por cento dos pacientes tiveram algum grau de atelectasias, no GB, 54 por cento (P=0,691). A capacidade vital foi estatisticamente maior no GB no PO (P<0,015). Todos os outros parâmetros de ventilometria, gasometria, manovacuometria e hemodinâmicos foram semelhantes entre os grupos. CONCLUSÃO: A cirurgia de revascularização do miocárdio leva à degradação da função respiratória no PO, e a aplicação da ventilação com pressão positiva (BiPAP®) pode ser benéfica para reestabelecer a função pulmonar mais rapidamente, principalmente a capacidade vital, de forma segura, sendo bem aceita pelos paciente, devido ao maior conforto em relação à sensação de dor durante a execução da fisioterapia respiratória.
INTRODUCTION: The application of two levels of ventilation by positive pressure (BiPAP®) associated with conventional respiratory therapy (CRT) in postoperative periord of cardiac surgery may contribute to reduction of pulmonary complications. OBJECTIVES: To evaluate the safety and compliance of preventive application of BiPAP® CRT associated with immediate postoperative myocardial revascularization. METHODS: 26 patients undergoing coronary artery bypass grafting were randomly allocated in one of the groups. Patients of the Control Group (CG) were treated only with conventional respiratory therapy, compared to BiPAP group (BG) (in addition to conventional respiratory therapy the patients were subjected to 30 minutes of ventilation by two levels twice a day). The conventional respiratory therapy was held in both groups, twice a day. All patients were evaluated for vital capacity, airway permeability, maximal respiratory pressures, oxygen saturation, heart rate, respiratory frequency, Volume Minute, tidal volume, systolic and diastolic blood pressure. Evaluations were performed during hospitalization preoperatively, immediately after extubation, 24h and 48h after extubation. RESULTS: In CG 61.5 percent of patients had some degree of atelectasias, in comparison to 54 percent of BG (P=0.691). The vital capacity was higher in the GB postoperatively (P<0.015). All the other ventilometric, gasometric, hemodynamic and manometric parameters were similar between groups. CONCLUSION: Coronary artery bypass grafting leads to deterioration of respiratory function postoperatively, and the application of positive pressure ventilation (BiPAP®) may be beneficial to restore lung function more quickly, especially vital capacity, safely, and well accepted by patients due to greater comfort with the sensation of pain during the execution of respiratory therapy.
Subject(s)
Female , Humans , Male , Coronary Artery Bypass/rehabilitation , Positive-Pressure Respiration/methods , Postoperative Care/methods , Pulmonary Atelectasis/prevention & control , Vital Capacity/physiology , Positive-Pressure Respiration/adverse effects , Postoperative Care/adverse effects , Pulmonary Atelectasis/etiologyABSTRACT
La atelectasia es una complicación frecuente en pacientes bajo ventilación mecánica artificial que aumenta la estadía, los costos y la mortalidad de los pacientes en la unidad de cuidados intensivos, representa un problema sin resolver para el paciente ventilado, tiene efecto deletéreo sobre algunos parámetros ventilatorios como la diferencia álveolo-arterial de oxígeno, la relación entre presión de oxígeno y fracción inspirada de oxígeno y la compliancia pulmonar, la broncofibroscopia es efectiva para prevenirla, diagnosticarla y tratarla en este grupo de enfermos. Obtener muestras de secreciones respiratorias para estudios microbiológicos en pacientes ventilados ha sido un tema muy debatido en la literatura médica, disminuir la frecuencia de neumonía asociada a la ventilación mecánica y aislar el germen responsable es muy útil para la elección del antimicrobiano, la broncofibroscopia demuestra ser superior a otras técnicas incluida la aspiración con sondas a ciegas en los pacientes ventilados
Atelectasis is a frequent complication in patients on artificial ventilation which increases the stay, cost and mortality of patients in the intensive care unit is an unsolved problem for the ventilated patient, has deleterious effect on some ventilatory parameters as alveolar-arterial oxygen difference, the relationship between oxygen pressure and fraction of inspired oxygen and lung compliance, bronchoscopy is effective to prevent, diagnose it and treat it in this group of patients. Get samples of respiratory secretions for microbiologic studies in ventilated patients has been a very debated topic in the literature, reducing pneumonia frequency associated with mechanical ventilation and isolate the responsible germ is very useful for the choice of antimicrobial, the bronchoscopy shows be superior to other techniques including aspiration probe blindly in ventilated patients
Subject(s)
Humans , Male , Female , Pulmonary Atelectasis/etiology , Pulmonary Atelectasis/therapy , Bronchoscopy/methods , Mucus/microbiology , Respiratory System , Respiration, Artificial/adverse effectsABSTRACT
Tumores glômicos são raras neoplasias benignas de tecidos moles. Relatamos o caso de um paciente de 32 anos de idade que apresentava atelectasia em lobo superior direito devido a um tumor endobrônquico. O paciente foi submetido a lobectomia superior direita e broncoplastia em cunha. O diagnóstico patológico foi de tumor glômico endobrônquico. Até onde sabemos, essa apresentação com atelectasia em lobo superior direito nunca foi relatada. O tumor glômico deve ser considerado no diagnóstico diferencial de lesões endobrônquicas que causam atelectasia lobar.
Glomus tumors are uncommon benign soft tissue neoplasms. We report the case of a 32-year-old male who presented with right upper lobe atelectasis due to an endobronchial tumor. The patient underwent right upper lobectomy and wedge bronchoplasty. The pathological diagnosis was bronchial glomus tumor. To our knowledge, this presentation (with right upper lobe atelectasis) has never before been reported. Glomus tumor should be considered in the differential diagnosis of endobronchial lesions causing lobar atelectasis.
Subject(s)
Adult , Humans , Male , Bronchial Neoplasms/complications , Glomus Tumor/complications , Pulmonary Atelectasis/etiology , Bronchial Diseases/diagnosis , Bronchial Neoplasms/pathology , Diagnosis, Differential , Glomus Tumor/pathologyABSTRACT
Myasthenia gravis (MG) is often complicated by respiratory failure, known as a myasthenic crisis. However, most of the patients who develop respiratory symptoms do so during the late course of disease and have other neurological signs and symptoms. However, in some patients respiratory failure is the initial presenting symptom. We report the case of a 68-year-old woman with MG who presented with isolated respiratory failure as her first presenting symptom. As illustrated by this case, it is important to consider neuromuscular disorders in cases of unexplained respiratory failure.
Subject(s)
Aged , Female , Humans , Acute Disease , Electromyography , Myasthenia Gravis/complications , Pulmonary Atelectasis/etiology , Respiratory Insufficiency/etiology , Tomography, Spiral ComputedABSTRACT
Objetivo: Descrever as características clínicas, radiológicas e endoscópicas da aspiração de corpo estranho por menores de 15 anos em um centro de referência em São Luís, MA. Métodos: Estudo descritivo realizado a partir de dados de prontuários dos pacientes atendidos no Hospital Universitário Materno Infantil devido à aspiração decorpo estranho entre 1995 e 2005. Avaliamos 72 casos confirmados de aspiração de corpo estranho em relação à procedência, variáveis biológicas, clínico-radiológicas e endoscópicas. Para verificar se as frequências observadas das variáveis em estudo foram estatisticamente significantes, utilizamos o teste do qui-quadrado. Resultados: A maioria do pacientes era procedente das cidades do interior (55,6%). As maiores frequências das diferentes variáveis estudadas foram as seguintes: faixa etária de 0-3 anos (81,9%); sexo masculino (63,9%); tempo de evolução > 24 h (66,7%); hipotransparência na radiografia de tórax (57,7%); localização do corpo estranho no pulmão direito (41,2%) ou na laringe (20.5%); natureza orgânica do corpo estranho (83,3%); complicação como processo inflamatório localizado (59,4%); edema de glote como complicação do exame endoscópico (47,6%); e sementes(46,6%), espinha de peixe (28,3%) e plásticos (25,5%) como tipos mais frequentes de corpos estranhos aspirados. Não houve óbitos. Conclusões: Cuidados preventivos devem priorizar crianças menores de três anos de idade, do sexo masculino, provenientes de cidades do interior. O acesso dessas crianças às substâncias com risco potencial para aspiração, incluindo os alimentos, deve ser evitado. Exames radiológicos simples e de fácil acesso à população são subutilizados, o que compromete a qualidade do primeiro atendimento.
Objective: To describe the clinical, radiological and endoscopic characteristics of foreign body aspiration among individuals under the age of 15 treated at a referral center in the city of São Luís, Brazil. Methods: This was a descriptive study using data from the medical charts of patients treated for foreign body aspiration at theHospital Universitário Materno Infantil between 1995 and 2005. We investigated 72 confirmed cases of foreign body aspiration, evaluating the place of residence, as well as biological, clinical, radiological and endoscopicvariables. We used the chi-square test to identify statistically significant differences in frequency among thevariables studied. Results: The majority of the patients were from outlying areas (55.6%). The following variables presented the highest frequencies: 0-3 year age bracket (81.9%); male gender (63.9%); evolution > 24 h (66.7%);hypotransparency on chest X-ray (57.7%); foreign body in the right lung (41.2%) or in the larynx (20.5%); organic nature of the foreign body (83.3%); complication in the form of localized inflammation (59.4%); glottal edema as an endoscopic complication (47.6%); and seeds (46.6%), fishbone (28.3%) or plastics (25.5%) as the type of foreign body. There were no deaths. Conclusions: Preventive care should be a priority for male children under the age of 3 living in outlying areas. Such children should not be given access to substances that can be aspirated, including certain foodstuffs. Simple and easily accessible radiological tests have been underused, which jeopardizes the quality of the initial treatment.
Subject(s)
Adolescent , Child , Child, Preschool , Female , Humans , Infant , Male , Bronchoscopy , Foreign Bodies/diagnosis , Larynx , Lung , Brazil , Forced Expiratory Volume , Foreign Bodies/complications , Foreign Bodies , Foreign-Body Reaction/etiology , Hospitals, University , Inhalation , Larynx , Lung , Maternal-Child Health Centers , Pulmonary Atelectasis/etiologyABSTRACT
An aspirated foreign body continues to present serious challenge of airway management to anesthesiologists perioperatively. These patients usually present with respiratory distress and require a high index of suspicion; need prompt assessment and recognition of the potential cause, and emergency management to obtain the best possible outcome. Nasal packing after ENT surgery has been previously reported to result in complications. A nasal pack obstructing left bronchus completely and right bronchus partially, resulting in post obstructive pulmonary edema is reported. This patient had aspirated the nasal pack in recovery room after tracheal extubation. The case highlights the need for close postoperative monitoring in patients with nasal packs, the diagnostic role of fibroptic bronchoscope and therapeutic role of rigid bronchoscope in airway obstruction
Subject(s)
Humans , Male , Pulmonary Atelectasis/etiology , Nose , Airway Obstruction , Pulmonary EdemaABSTRACT
OBJETIVO: Realizar uma revisão da literatura sobre os mecanismos, diagnóstico e tratamento das atelectasias pulmonares em pediatria. MÉTODOS:Efetuou-se uma pesquisa nos bancos de dados eletrônicos Medline e Scielo com os critérios de inclusão: artigos publicados entre os anos de 1960 e 2007, que abordassem a etiologia, fisiopatologia, conseqüências funcionais, avaliação, prevenção, tratamento e complicações das atelectasias pulmonares em pediatria. Palavras-chave: atelectasis, children, pediatrics, mucus plugs, chest physiotherapy; atelectasias, criança, pediatria, fisioterapia respiratória, secreção brônquica. Utilizou-se o escore de Sackett DL, 1989 para a classificação do nível de evidência dos artigos encontrados. RESULTADOS:Foram analisados 45 artigos sobre atelectasias pulmonares, sendo 17 artigos em pediatria. Dos artigos com pacientes pediátricos, 13 estudos com série de casos clínicos, três artigos de revisão da literatura e um relato de caso, demonstrando que poucos artigos abordando atelectasias em pediatria foram publicados no período da pesquisa e que o nível de evidência dos artigos existentes são D e E. CONCLUSÃO: Poucos estudos clínicos foram realizados atualmente para identificar o tratamento mais eficaz para a resolução das atelectasias em pediatria. Embora a prática clínica tenha evoluído no tratamento das mesmas, com o aperfeiçoamento das técnicas de broncoscopia e da fisioterapia respiratória existe a necessidade da realização de estudos clínicos randomizados nesta área.
OBJECTIVE: To review the literature about mechanisms, diagnosis and treatment of atelectasis in the pediatric patient. METHODS: An electronic data search was carried out in Medline and Scielo using the following inclusion criteria for articles published between 1960 and 2007 about: atelectasis etiology, physiopathology, functional consequences, evaluation, prevention, treatment and complications, in pediatrics. The used key words were atelectasis, children, pediatrics, mucus plugs, chest physiotherapy; RESULTS: 45 pulmonary atelectasis articles were analyzed, 17 of them in pediatrics. Of the pediatric, 13 were case series, 3 literature reviews and one a case report. This demonstrates that there were few articles on atelectasis during the reviewed period and that these articles were at the D and E evidence level. CONCLUSION: No clinical trials were performed to identify s the most efficient treatment for atelectasis in the pediatric patient. Although clinical practice for treatment of atelectasis has evolved, mostly due to improvement of bronchoscopy and chest physiotherapy techniques, there is still a need to perform randomized clinical trials to address treatment of atelectasis in the pediatric patient.
Subject(s)
Child , Humans , Pulmonary Atelectasis , Clinical Trials as Topic/statistics & numerical data , Evidence-Based Medicine/standards , Pulmonary Atelectasis/diagnosis , Pulmonary Atelectasis/etiology , Pulmonary Atelectasis/physiopathology , Pulmonary Atelectasis/prevention & controlABSTRACT
OBJETIVO: Avaliar a incidência e o risco de complicações pulmonares em crianças submetidas a intervenção fisioterapêutica pré e pós-operatória nas cirurgias cardíacas, bem como comparar com aquelas submetidas apenas a intervenção fisioterapêutica pós-operatória. MÉTODOS: Ensaio clínico aleatório, que incluiu 135 pacientes de zero a 6 anos com cardiopatias congênitas, submetidos à cirurgia cardíaca. Os pacientes foram aleatorizados para grupo intervenção (G1), que realizou fisioterapia pré e pós-operatória, ou para grupo controle (G2), somente fisioterapia pós-operatória. Para comparar as variáveis entre os grupos foi utilizado o teste de Mann-Whitney e o Qui quadrado. Foi calculado o risco absoluto e sua magnitude por meio do número necessário para tratar. A significância estatística foi estipulada em 5% (P<0,05). RESULTADOS: No G1, 17 (25%) pacientes tiveram complicação pulmonar e, no G2, foram 29 (43,3%) (p=0,025). A complicação mais freqüente foi pneumonia e, dos 17 pacientes do G1 que complicaram, sete (10,3%) desenvolveram pneumonia, seis (8,8%) atelectasia e quatro (5,9%) associação das duas. No G2, 13 (19,4%) pacientes tiveram pneumonia, oito (11,9%), atelectasia, e oito (11,9%), pneumonia associada à atelectasia. A redução do risco absoluto para o desfecho primário foi de 18,3% e o número necessário para tratar foi calculado em 5,5. CONCLUSÃO: A fisioterapia respiratória pré-operatória reduziu significativamente o risco de desenvolvimento de complicações pulmonares no pós-operatório de cirurgia cardíaca pediátrica.
OBJECTIVE: To evaluate the occurrence and risk of pulmonary complications in children who underwent pre-and postoperative physiotherapeutic intervention in cardiac surgeries, as well as to compare these patients to those who underwent only postoperative physiotherapeutic intervention. METHODS: A randomized controlled trial was performed with 135 patients from 6 years of age and younger with congenital heart disease who had undergone cardiac surgery. Patients were randomly assigned to the intervention group (G1) in which they underwent pre- and postoperative physiotherapy or to the control group (G2) in which they underwent only postoperative physiotherapy. Mann-Whitney and the Chi-square tests were used to compare the variables between the groups. The magnitude of the absolute risk was calculated by the number of patients needed to treat. Statistical significance was set at 5% (P<0.05). RESULTS: 17 patients (25%) in G1, and 29 patients (43.3%) in G2 presented pulmonary complications (P= 0.025), pneumonia was the most frequent complication, and among the 17 patients in G1, seven (10.3%) developed pneumonia, six (8.8%) developed atelectasis, and four (5.9%) presented complications due to both complications. In G2, 13 patients (19.4%) developed pneumonia, eight (11.9%) developed atelectasis, and eight (11.9%) developed pneumonia associated with atelectasis. Absolute risk reduction for the primary outcome was of 18.3% and the number of needed to treat was 5.5. CONCLUSION: Preoperative respiratory physiotherapy significantly reduced the risk of pulmonary complications in postoperative pediatric cardiac surgery.