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1.
Revista brasileira de ciência e movimento ; 29(1): [1-23], nov. 2021. tab, ilus
Article in Portuguese | LILACS | ID: biblio-1344082

ABSTRACT

: Este estudo investigou o impacto de 5 semanas de treinamento pliométrico em membros superiores e inferiores sobre o desempenho físico em estudantes de Educação Física. Foram recrutados 16 estudantes do sexo masculino de 18 a 23 anos divididos em 2 grupos (Controle e Treino). O grupo Treino foi submetido ao treinamento pliométrico de membros superiores e inferiores por 5 semanas com 3 sessões/semana de 30-40 minutos/sessão, composta de 10 exercícios de braço e perna (10-20 repetições/exercício). Antes e imediatamente após o programa de treinamento pliométrico, os indivíduos foram avaliados por parâmetros antropométricos (peso, estatura, índice de massa corporal e percentual de gordura), nível de flexibilidade e desempenho físico (forças de toque e de ataque, salto vertical, sprint de 20 m e agilidade). Dados de flexibilidade e desempenho físico foram avaliados por análise de covariância (ANCOVA), além da correlação de Pearson entre as variáveis de desempenho físico após 5 semanas de treinamento. O grupo Treino exibiu maior ganho de desempenho no salto vertical quando comparado ao grupo Controle (p< 0,05). Todavia, não foi observada diferença significativa entre os grupos Treino e Controle nos ganhos de força de toque e de ataque, no desempenho do teste de sprint de 20 m, no teste de agilidade e de flexibilidade (p> 0,05). Houve correlação positiva entre os testes de forças de toque e de ataque com o salto vertical (p< 0,001, r= 0,633; e p< 0,001, r= 0,639; respectivamente), como também correlação dos testes salto vertical com os testes de velocidade (p< 0,001, r= -0,768) e agilidade (p< 0,002, r= -0,537) após o treinamento. Conclui-se que 5 semanas de treinamento pliométrico de membros superiores e inferiores exibiram melhora no desempenho do salto vertical de estudantes de Educação Física, bem como observou-se correlação entre os parâmetros neuromusculares anaeróbicos de membros inferiores e superiores após o período de treinamento.(AU)


This study investigated the impact of 5 weeks of plyometric training on upper and lower limbs on physical performance parameters in Physical Education students. Sixteen male college students aged 18 to 23 years were divided into 2 groups (Control and Training). The Training group was submitted to 5 weeks of plyometric training for upper and lower limbs, with 3 sessions per week for 30-40 minutes per session. Training sessions consisted of 10 arm and leg exercises (10-20 repetitions per exercise). Anthropometric parameters (weight, height, body mass index and body fat percentage), level of flexibility and physical performance (touch and attack strength, vertical jump, 20m sprint, agility) were assessed before and immediately after the plyometric training program. Flexibility and physical performance data were assessed by covariance analysis (ANCOVA), in addition to Pearson's correlation among physical performance parameters after 5 weeks of training. The Training group showed a greater gain in the vertical jump performance when compared to the Control group. However, no significant difference was observed between the Training and Control groups for touch and attack strength gains, for 20 m sprint performance gains, and for agility and flexibility test gains. There was a positive correlation between the tests of touch and attack strengths with vertical jump performance. There was also positive correlation between touch and attack strength with vertical jump (p< 0.001, r= 0.633; e p< 0,001, r= 0.639; respectively), and between vertical jump performance and 20m sprint performance (p< 0.001, r= -0,768) and agility test after training (p< 0.002, r= -0,537). It is concluded that 5 weeks of plyometric training for upper and lower limbs showed improvement in the vertical jump performance in Physical Education students. There was also a correlation between the anaerobic neuromuscular parameters of lower and upper limbs after the training period.(AU)


Subject(s)
Humans , Male , Adolescent , Adult , Reaction Time , Athletic Performance , Resistance Training , Plyometric Exercise , Physical Education and Training , Students , Anthropometry , Lower Extremity , Upper Extremity , Mentoring
2.
Rev. cuba. invest. bioméd ; 40(1): e856, ene.-mar. 2021. tab, graf
Article in Spanish | LILACS, CUMED | ID: biblio-1289444

ABSTRACT

Introducción: La identificación de variables antropométricas relacionadas con el rendimiento en un deporte representa un interés en común para los profesionales de la salud y el deporte. Objetivo: Determinar la influencia del índice de masa corporal, la masa grasa y la masa libre de grasa en la velocidad con cambios de dirección en jóvenes futbolistas. Métodos: Se aplicó un estudio descriptivo de tipo correlacional con un enfoque cuantitativo y una muestra a conveniencia conformada por 21 futbolistas. Para valorar la velocidad con cambios de dirección se utilizó el Test de sprint 20 metros con cambios de dirección y el porcentaje de grasa corporal por medio de un monitor OMRON® BF-306. Los datos fueron analizados en el paquete estadístico PSPP en el cual se aplicó la prueba de normalidad de Shapiro-Wilk y el coeficiente correlacional de Pearson (95 por ciento de confianza y un p-valor de 0,05). Resultados: Los resultados reflejaron una distribución normal (p > 0,05); sin embargo, no se obtuvieron relaciones significativas entre el índice de masa corporal (r = -0,29), masa grasa (r = -0,06) y masa libre de grasa (r = 0,06; p > 0,05) con el rendimiento en la prueba de velocidad con cambios de dirección. Conclusiones: Este estudio permitió establecer que no existe relación significativa entre el índice de masa corporal, masa grasa y masa libre de grasa con el rendimiento de la velocidad con cambios de dirección en jóvenes futbolistas(AU)


Introduction: Identification of anthropometric variables related to performance in a given sport is a common topic of interest to health and sports professionals. Objective: Determine the influence of body mass index, fat mass, and fat-free mass on change of direction speed in young soccer players. Methods: A correlational descriptive quantitative study was conducted of a convenience sample of 21 soccer players. Change of direction speed was measured with the Meters Swerve Sprint Test, whereas body fat percentage was evaluated with an OMRON® BF-306 monitor. The data were analyzed with the statistical package PSPP, with application of the Shapiro-Wilk normality test and Pearson's correlational coefficient (confidence interval 95 percent and p-value 0,05). Results: Results show a normal distribution (p > 0,05). However, a significant relationship was not found between body mass (r = -0,29), fat mass (r = -0,06) and fat-free mass (r = 0,06; p > 0,05), and performance in the swerve speed test. Conclusions: The study found that there is not a significant relationship between body mass index, fat mass and fat-free mass, and change of direction speed in young soccer players(AU)


Subject(s)
Humans , Male , Female , Soccer , Sports , Body Mass Index , Adipose Tissue , Adiposity , Reaction Time , Confidence Intervals , Anthropometry/methods , Epidemiology, Descriptive , Correlation of Data
3.
Adv Rheumatol ; 61: 10, 2021. tab, graf
Article in English | LILACS | ID: biblio-1152740

ABSTRACT

Abstract Background: Fibromyalgia is a chronic pain disorder characterized by widespread musculoskeletal symptoms, primarily attributed to sensitization of somatosensory system carrying pain. Few reports have investigated the impact of fibromyalgia symptoms on cognition, corticomotor excitability, sleepiness, and the sleep quality — all of which can deteriorate the quality of life in fibromyalgia. However, the existing reports are underpowered and have conflicting directions of findings, limiting their generalizability. Therefore, the present study was designed to compare measures of cognition, corticomotor excitability, sleepiness, and sleep quality using standardized instruments in the recruited patients of fibromyalgia with pain-free controls. Methods: Diagnosed cases of fibromyalgia were recruited from the Rheumatology department for the cross-sectional, case-control study. Cognition (Mini-Mental State Examination, Stroop color-word task), corticomotor excitability (Resting motor threshold, Motor evoked potential amplitude), daytime sleepiness (Epworth sleepiness scale), and sleep quality (Pittsburgh sleep quality index) were studied according to the standard procedure. Results: Thirty-four patients of fibromyalgia and 30 pain-free controls were recruited for the study. Patients of fibromyalgia showed decreased cognitive scores (p = 0.05), lowered accuracy in Stroop color-word task (for color: 0.02, for word: 0.01), and prolonged reaction time (< 0.01, < 0.01). Excessive daytime sleepiness in patients were found (< 0.01) and worsened sleep quality (< 0.01) were found. Parameters of corticomotor excitability were comparable between patients of fibromyalgia and pain-free controls. Conclusions: Patients of fibromyalgia made more errors, had significantly increased reaction time for cognitive tasks, marked daytime sleepiness, and impaired quality of sleep. Future treatment strategies may include cognitive deficits and sleep disturbances as an integral part of fibromyalgia management.(AU)


Subject(s)
Humans , Fibromyalgia/diagnosis , Cognition , Chronic Pain , Sleep Hygiene , Cortical Excitability , Reaction Time , Pain Measurement/instrumentation , Case-Control Studies , Cross-Sectional Studies , Stroop Test , Observational Study
4.
Rev. CEFAC ; 23(2): e1220, 2021. tab, graf
Article in English | LILACS | ID: biblio-1155329

ABSTRACT

ABSTRACT Purpose: to analyze forward masking in normally hearing young people, by using frequency-following responses. Methods: the synthetic syllable /da/ was used for the recordings of ten individuals, in the following conditions: /da/ with no masking, and /da/ after 4, 16, 32, and 64 milliseconds of masking. F-test (ANOVA) was applied for repeated measures with the Greenhouse-Geisser correction to compare testing conditions. For significant differences, multiple comparisons (between pairs of conditions) and Bonferroni correction were used. Data normality was verified by applying the Shapiro-Wilk test, and statistical significance was used at 5%. Results: wave latencies of all masking conditions were compared with those of no masking. A latency delay was observed in the transient region of the response (PV and A) in all masking conditions, except for 64 milliseconds. Latency delay also occurred for waves PW, PX, and PY, which corresponded to the sustained region of the response. Conclusion: forward masking was observed, by using frequency-following responses with /da/ syllable in four intervals (4, 16, 32, and 64 ms) of preceding masking. Forward masking was more evident in the transient region of the response than in the sustained one. This study highlights the importance of electrophysiological testing in temporal processing assessment.


Subject(s)
Pitch Perception/physiology , Evoked Potentials/physiology , Reaction Time , Cross-Sectional Studies , Electrophysiological Phenomena
5.
Acta Physiologica Sinica ; (6): 286-294, 2021.
Article in Chinese | WPRIM | ID: wpr-878257

ABSTRACT

Many studies have shown that high-altitude exposure could significantly influence human cognition, and the approaches which could enhance the human cognition in high-altitude hypoxia environment attract great attention. In the present study, we recruited a total of 60 subjects who had been migrated to Tibet University as adults for more than one year. These participants were randomly divided into the experimental group and the control group. The participants in the experimental group were instructed to complete a hyperbaric oxygen treatment, and those in the control group just completed a wait condition. By using the attention network test (ANT), the changes of the attention function before and after a single session of hyperbaric oxygen treatment were explored. The results showed that single hyperbaric oxygen treatment significantly improved the orienting function of attention, with an obvious post-intervention effect, but not the alerting and conflict function of attention. We also found a strong association between alerting function and conflict function after the end of intervention, suggesting the change of the overall performance of attention function. The present findings might suggest that the improvement of attention function by a single session of hyperbaric oxygen intervention is derived from the increase of general cognitive resources, rather than the transfer of cognitive resources within the attention system.


Subject(s)
Adult , Humans , Hyperbaric Oxygenation , Orientation , Oxygen , Reaction Time , Tibet , Transients and Migrants
6.
Article in Chinese | WPRIM | ID: wpr-888221

ABSTRACT

Transcranial direct current stimulation (tDCS) is a non-invasive low-current brain stimulation technique, which is mainly based on the different polarity of electrode stimulation to make the activation threshold of neurons different, thereby regulating the excitability of the cerebral cortex. In this paper, healthy subjects were randomly divided into three groups: anodal stimulation group, cathodal stimulation group and sham stimulation group, with 5 subjects in each group. Then, the performance data of the three groups of subjects were recorded before and after stimulation to test their mental rotation ability, and resting state and task state electroencephalogram (EEG) data were collected. Finally, through comparative analysis of the behavioral data and EEG data of the three groups of subjects, the effect of electrical stimulation of different polarities on the three-dimensional mental rotation ability was explored. The results of the study found that the correct response time/accuracy rate and the accuracy rate performance of the anodal stimulation group were higher than those of the cathodal stimulation and sham stimulation groups, and there was a significant difference (


Subject(s)
Electric Stimulation , Electroencephalography , Frontal Lobe , Humans , Reaction Time , Transcranial Direct Current Stimulation
7.
CoDAS ; 33(2): e20190207, 2021. tab, graf
Article in Portuguese | LILACS | ID: biblio-1249608

ABSTRACT

RESUMO Objetivo Identificar e analisar quais são os achados característicos dos Potenciais Evocados Auditivos Corticais (PEAC) em crianças e/ou adolescentes com Transtorno do Espectro do Autismo (TEA) em comparação do desenvolvimento típico, por meio de uma revisão sistemática da literatura. Estratégia de pesquisa Após formulação da pergunta de pesquisa, foi realizada uma revisão da literatura em sete bases de dados (Web of Science, Pubmed, Cochrane Library, Lilacs, Scielo, Science Direct, e Google acadêmico), com os seguintes descritores: transtorno do espectro autista (autism spectrum disorder), transtorno autístico (autistic disorder), potenciais evocados auditivos (evoked potentials, auditory), potencial evocado P300 (event related potentials, P300) e criança (child). A presente revisão foi cadastrada no Próspero, sob número 118751. Critérios de seleção Foram selecionados estudos publicados na integra, sem limitação de idioma, entre 2007 e 2019. Análise dos dados: Foram analisadas as características de latência e amplitude dos componentes P1, N1, P2, N2 e P3 presentes nos PEAC. Resultados Foram localizados 193 estudos; contudo 15 estudos contemplaram os critérios de inclusão. Embora não tenha sido possível identificar um padrão de resposta para os componentes P1, N1, P2, N2 e P3, os resultados da maioria dos estudos demonstraram que indivíduos com TEA podem apresentar diminuição de amplitude e aumento de latência do componente P3. Conclusão Indivíduos com TEA podem apresentar respostas diversas para os componentes dos PEAC, sendo que a diminuição de amplitude e aumento de latência do componente P3 foram as características mais comuns.


ABSTRACT Purpose To identify and analyze what are the characteristic findings of Cortical Auditory Evoked Potentials (CAEP) in children and / or adolescents with Autism Spectrum Disorder (ASD) compared to typical development, through a systematic literature review. Research strategies Based on the formulation of a research question, a bibliographic survey was carried out in seven databases (Web of Science, Pubmed, Cochrane Library, Lilacs, Scielo, Science Direct, and Google Sholar), with the following descriptors: autism spectrum disorder (transtorno do espectro autista), autistic disorder (transtorno autístico), evoked potentials, auditory (potenciais evocados auditivos), event related potentials, P300 (potencial evocado P300) e child (criança). This review was registered in Prospero, under number 118751. Selection criteria Were selected articles published, without language limitation, between 2007 and 2019. Data analysis The characteristics of the latency and amplitude aspects of the P1, N1, P2, N2 and P3 components present in the CAEP. Results 193 studies were located; however, 15 original articles were included the inclusion criteria for this study. Although it has not been possible to identify any pattern of response for the P1, N1, P2 and N2 components, the results of the selected studies have demonstrated that individuals with ASD may present a decrease in amplitude and increase in latency of the P3 component. Conclusion Individuals with ASD may present different responses to the components of the CAEP, and the decrease of the amplitude and increase of the latency of the P3 component were the most common characteristics.


Subject(s)
Humans , Child , Adolescent , Autistic Disorder , Autism Spectrum Disorder , Reaction Time , Acoustic Stimulation , Surveys and Questionnaires , Evoked Potentials, Auditory
8.
Ciênc. cuid. saúde ; 20: e58193, 2021. tab
Article in Portuguese | LILACS, BDENF | ID: biblio-1356104

ABSTRACT

RESUMO Objetivo: analisar perfil, evolução e desfecho dos pacientes atendidos pelo SAMU 192. Método: estudo transversal, exploratório e descritivo. A amostra constou dados de 600 pacientes adultos, atendidos no ano de 2015 pelo SAMU e encaminhados para outro serviço de saúde. Realizou-se análise descritiva para identificar o perfil da população, a evolução e o desfecho intra-hospitalar; teste de correlação entre o tempo resposta no serviço pré-hospitalar e o tempo de internação; e regressão logística múltipla entre o tempo resposta e o desfecho. Utilizou-se p<0,05 como nível de significância. Resultados: predominaram o atendimento de ocorrências clínicas, o sexo masculino e a média de idade de 55,5 anos. Após o atendimento pré-hospitalar, 50,2% dos pacientes permaneceram em observação e 34,8% precisaram de internação hospitalar. O tempo resposta pré-hospitalar apresentou correlação positiva com o tempo de internação. O principal desfecho foi a alta médica, sendo que 41% deles foram encaminhados para continuidade do tratamento. Conclusão: a análise mostrou um perfil de atendimentos a pacientes com idade média de 55 anos e acometidos por doenças de natureza clínica que necessitaram de encaminhamento a uma unidade de saúde, permanecendo em observação hospitalar por até 12h. Esses resultados são importantes para o embasamento de protocolos de fluxo assistencial na RUE, a fim de diminuir a sobrecarga dos serviços terciários.


RESUMEN Objetivo: analizar el perfil, la evolución y el desenlace de los pacientes asistidos por el SAMU 192. Método: estudio transversal, exploratorio y descriptivo. La muestra estuvo compuesta por datos de 600 pacientes adultos, atendidos en el año 2015 por el SAMU y encaminados a otro servicio de salud. Se realizó un análisis descriptivo para identificar el perfil de la población, la evolución y el desenlace intrahospitalario; prueba de correlación entre tiempo de respuesta en el servicio prehospitalario y duración de la hospitalización; y regresión logística múltiple entre el tiempo de respuesta y el desenlace. El nivel de significación utilizado fue p<0,05. Resultados: predominaron la atención a los casos clínicos, el género masculino y la edad promedio de 55,5 años. Después de la atención prehospitalaria, el 50,2% de los pacientes permaneció en observación y el 34,8% necesitó hospitalización. El tiempo de respuesta prehospitalaria se correlacionó positivamente con la duración de hospitalización. El desenlace principal fue el alta médica, con un 41% de ellos encaminado para la continuidad del tratamiento. Conclusión: el análisis mostró un perfil de atención a pacientes con edad promedio de 55 años y afectados por enfermedades clínicas que requirieron encaminamientos a una unidad de salud, permaneciendo en observación hospitalaria hasta 12h. Estos resultados son importantes para el establecimiento de protocolos de flujo asistencial en la RUE, con miras a reducir la sobrecarga de los servicios terciarios.


ABSTRACT Objective: to analyze the profile, the evolution and outcome of patients served by the SAMU 192. Method: cross-sectional, exploratory and descriptive study. The sample consisted of data from 600 adult patients, served in the year 2015 by the SAMU and referred to another health service. Descriptive analysis was performed to identify the population profile, the evolution and the intra-hospital outcome; correlation testing between response time in the pre-hospital service and length of stay; and multiple logistic regression between response time and outcome. It used p<0.05 as the significance level. Results: there was a predominance of care for clinical occurrences, male gender and average age of 55.5 years. After pre-hospital care, 50.2% of the surveyed patients remained under observation and 34.8% required hospitalization. The pre-hospital response time was positively correlated with the length of stay. The main outcome was medical discharge, with 41% of them being referred for the continuity of treatment. Conclusion: the analysis showed a profile of care provided to patients with an average age of 55 years and suffering from clinical diseases that required referral to a health unit, remaining under hospital observation for up to 12 hours. These results are important for the support of care flow protocols in the RUE, in order to reduce the overload of tertiary services.


Subject(s)
Humans , Male , Female , Continuity of Patient Care , Emergency Medical Services , Patient Discharge , Reaction Time , Referral and Consultation , Therapeutics , Nursing , Answering Services , Emergencies , Prehospital Care , Health Services , Hospitalization , Length of Stay
9.
Rev. epidemiol. controle infecç ; 10(3): 1-13, jul.-set. 2020. ilus
Article in Portuguese | LILACS | ID: biblio-1247354

ABSTRACT

Justificativa e Objetivos: analisar o Golden time desenvolvido pelo serviço de atendimento móvel de urgência (SAMU) da cidade de Floriano, Piauí, Brasil. Justifica-se por haver poucas produções que enfatizam primordialmente o tempo (Golden Hour), tornando-se imprescindível aos estudantes e profissionais da área, mostrando que ter domínio e conhecimento do mesmo, pode salvar vidas. Métodos: Trata-se de um estudo descritivo, documental e, abordagem quantitativa realizado a partir dos registros na ficha de atendimento referente ao ano de 2018, a partir do levantamento das variáveis das etapas do Golden time, natureza e tempo do evento, e analisados por meio de estatística descritiva e inferencial.O presente estudo atendeu a todos os preceitos éticos com base no parecer de aprovação do comitê de ética (n° 96443518.4.0000.5660) Resultados: O Golden time mais frequentemente, em 58,5% dos casos, desenvolvido pelo SAMU foi de 15 a 30 minutos. As urgências e emergências clínicas em adultos foram os tipos de eventos mais comumente atendidos (35,50%). Conclusão O atendimento de maior frequência do SAMU de Floriano foi os casos de urgência e emergências clinicas em adultos, juntamente com o tempo de 15 a 30min.(AU)


Background and Objectives: analyze the Golden team developed by the mobile emergency service (SAMU) in the city of Floriano, Piauí, Brazil. It is justified because there are few productions that primarily emphasize time (Golden Hour), making it essential for students and professionals in the field, showing that having knowledge and knowledge of it, can save lives. Methods: This is a descriptive, documentary and quantitative approach carried out based on the records in the attendance sheet for the year 2018, based on the survey of the variables of the Golden time stages, nature and time of the event, and analyzed by descriptive and inferential statistics. This study met all ethical principles based on the approval opinion of the ethics committee (n ° 96443518.4.0000.5660). Results: The golden time most often, in 58.5% of cases, developed by SAMU was 15 to 30 minutes. Adult emergencies and /emergencies were the types of events most commonly attended (35.50%). Conclusion: The most frequent service provided by Floriano's SAMU was urgent cases and clinical emergencies in adults, along with the time of 15 to 30 minutes.(AU)


Justificación y Objetivos: analizar el equipo de oro desarrollado por el servicio móvil de emergencia (SAMU) en la ciudad de Floriano, Piauí, Brasil. Se justifica porque son pocas las producciones que enfatizan primordialmente el tiempo (Hora Dorada), por lo que es fundamental para los estudiantes y profesionales del campo, demostrando que tener conocimiento y conocimiento del mismo, puede salvar vidas. Métodos: Se trata de un abordaje descriptivo, documental y cuantitativo realizado a partir de los registros en la hoja de asistencia del año 2018, a partir del relevamiento de las variables de las etapas del tiempo Dorado, naturaleza y tiempo del evento, y analizado mediante estadística descriptiva e inferencial. El presente estudio cumplió con todos los preceptos éticos basados en la opinión de aprobación del comité de ética (n ° 96443518.4.0000.5660).Resultados: El equipo de oro con mayor frecuencia, en el 58,5% de los casos, desarrollado por SAMU fue de 15 a 30 minutos. Las emergencias de adultos y / / emergencias fueron los tipos de eventos más concurridos (35,50%). Conclusión La asistencia más frecuente en SAMU en Floriano fueron casos urgentes y emergencias clínicas en adultos, junto con el tiempo de 15 a 30 minutos.(AU)


Subject(s)
Humans , Reaction Time , Emergency Medical Services
10.
Braz. j. otorhinolaryngol. (Impr.) ; 86(2): 191-200, March-Apr. 2020. tab, graf
Article in English | LILACS | ID: biblio-1132572

ABSTRACT

Abstract Introduction: Brainstem auditory evoked potentials in response to complex sounds, such as speech sounds, investigate the neural representation of these sounds at subcortical levels, and faithfully reflect the stimulus characteristics. However, there are few studies that utilize this type of stimulus; for it to be used in clinical practice it is necessary to establish standards of normality through studies performed in different populations. Objective: To analyze the latencies and amplitudes of the waves obtained from the tracings of brainstem auditory evoked potentials using speech stimuli in Brazilian neonates with normal hearing and without auditory risk factors. Methods: 21 neonates with a mean age of 9 days without risk of hearing loss and with normal results at the neonatal hearing screening were evaluated according to the Joint Committee on Infant Hearing protocols. Auditory evoked potentials were performed with speech stimuli (/da/ syllable) at the intensity of 80 dBNA and the latency and amplitude of the waves obtained were analyzed. Results: In the transient portion, we observed a 100% response rate for all analyzable waves (Wave I, Wave III, Wave V and Wave A), and these waves exhibited a latency <10 ms. In the sustained portion, Wave B was identified in 53.12% of subjects; Wave C in 75%; Wave D in 90.62%; Wave E in 96.87%; Wave F in 87.5% and Wave O was identified in 87.5% of subjects. The observed latency of these waves ranged from 11.51 ms to 52.16 ms. Greater similarity was observed for the response latencies, as well as greater amplitude variation in the studied group. Conclusions: Although the wave morphology obtained for brainstem evoked potentials with speech stimulation in neonates is quite similar to that of adults, a longer latency and greater variation in amplitude were observed in the waves analyzed.


Resumo Introdução: Os potenciais evocados auditivos de tronco encefálico para sons complexos, como, por exemplo, sons de fala, investigam a representação neural desses sons em níveis subcorticais e refletem com fidelidade as características do estímulo. No entanto, existem ainda poucos estudos que usam esse tipo de estímulo e para que possa ser usado na prática clínica é necessário estabelecer padrões de normalidade por meio de estudos em diferentes populações. Objetivo: Analisar as latências e as amplitudes das ondas obtidas nos traçados dos potenciais evocados auditivos de tronco encefálico por estímulo de fala em neonatos brasileiros com audição normal e sem risco auditivo. Método: Foram avaliados 21 neonatos com média de 9 dias, sem risco auditivo segundo o Joint Committe on Infant Hearing e com resultado normal para triagem auditiva neonatal. Fizeram-se potenciais evocados auditivos por estímulo de fala (sílaba /da/) na intensidade de 80 dBNA e analisaram-se a latência e a amplitude das ondas obtidas. Resultados: Na porção transiente observaram-se 100% de ocorrência de resposta para todas as ondas analisáveis (Onda I, Onda III, Onda V e Onda A) e esse conjunto de ondas apresentou latência inferior a 10 ms. Na porção sustentada a frequência de ocorrência da Onda B foi de 53,12%; da Onda C 75%; da Onda D 90,62%; da Onda E 96,87%; da Onda F 87,5% e da Onda O 87,5% e a latência observada dessas ondas variou de 11,51 ms a 52,16 ms. Observou-se maior similaridade nas latências das respostas e maior variação da amplitude no grupo estudado. Conclusões: Embora a morfologia das ondas obtidas para os potenciais evocados de tronco encefálico para o estímulo de fala em neonatos seja bastante semelhante às dos adultos, observou-se maior latência e maior variação da amplitude das ondas analisáveis.


Subject(s)
Humans , Male , Female , Infant, Newborn , Reaction Time/physiology , Speech/physiology , Acoustic Stimulation/methods , Evoked Potentials, Auditory, Brain Stem/physiology , Neonatal Screening
11.
Braz. j. otorhinolaryngol. (Impr.) ; 86(2): 185-190, March-Apr. 2020. tab
Article in English | LILACS | ID: biblio-1132564

ABSTRACT

Abstract Introduction: Tinnitus is a central auditory disorder in which different processing systems are involved as a network. One of these networks is memory. Previous studies have demonstrated some deficits in various types of memory in chronic tinnitus. Objectives: The main purpose of the present study was to investigate the semantic memory, which is not yet investigated in the tinnitus population. Methods: In this case-control study, 15 subjects with chronic tinnitus and 16 matched healthy controls were included. 40 semantically related and 40 semantically unrelated word pairs were presented to the participants in a counter-balanced fashion. They were asked to make decision about their semantic relatedness. Then the participants' reaction times and the accuracy of responses were calculated. Results: Mean of reaction times were significantly longer in the tinnitus group (M = 1034 ms, SD = 0.31) compared to the control group (Mean = 1016 ms, SD = 0.13), p < 0.05. However, no significant difference was found for the mean percentage of correct responses between the two groups. Conclusion: The current study provided behavioral evidence that chronic tinnitus can affect the semantic memory. Such behavioral outcomes may provide new insights into more research activities in the field of electrophysiology and neuroimaging in the tinnitus population.


Resumo Introdução: O zumbido é um distúrbio auditivo central, no qual diferentes sistemas de processamento estão envolvidos como em uma rede. Uma dessas redes é a memória. Estudos anteriores demonstraram alguns déficits em vários tipos de memória no zumbido crônico. Objetivos: Investigar a memória semântica, que ainda não foi investigada na população com zumbido. Método: Neste estudo de caso-controle, 15 indivíduos com zumbido crônico e 16 controles saudáveis pareados foram incluídos; 40 pares de palavras semanticamente relacionados e 40 semanticamente não relacionados foram apresentados aos participantes de forma contrabalançada. Eles foram instruídos a tomar decisões sobre sua relação semântica. Em seguida, os tempos de reação dos participantes e a precisão das respostas foram calculados. Resultados: A média dos tempos de reação foi significativamente maior no grupo com zumbido (M = 1,034 ms, DP = 0,31) em comparação ao grupo controle (média = 1,016 ms, DP = 0,13), p< 0,05. Entretanto, nenhuma diferença significante foi encontrada para a porcentagem média de respostas corretas entre os dois grupos. Conclusão: O presente estudo forneceu evidências comportamentais de que o zumbido crônico pode afetar a memória semântica. Tais resultados comportamentais podem levar a novas percepções em mais atividades de pesquisa no campo da eletrofisiologia e neuroimagem na população com zumbido.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Young Adult , Semantics , Tinnitus/complications , Memory Disorders/etiology , Reaction Time , Tinnitus/physiopathology , Word Association Tests , Case-Control Studies , Chronic Disease , Memory Disorders/diagnosis , Memory Disorders/physiopathology
12.
Acta Physiologica Sinica ; (6): 181-189, 2020.
Article in Chinese | WPRIM | ID: wpr-827069

ABSTRACT

Long-term exposure to high altitude affects spatial working memory. Previous studies have focused on the analysis of electroencephalogram (EEG) components in time domain rather than in frequency domain. To explore the influence of long-term high altitude exposure on time dynamic characteristics and neural oscillation process of the spatial working memory, n-back task combined with the technology of event related potential recording was performed on 20 young migrants who grew at low altitude before the age of 18 and moved to high altitude more than three years ago, and 21 young people who had never been to the high altitude. EEG data were recorded, and the time domain and frequency domain analyses were performed. The results showed that the response time was longer and the accuracy rate was lower under the 2-back condition in the high altitude group compared with those in low altitude group. The late positive potential (LPP) amplitude was more negative, P2 amplitude was more positive in the 2-back condition, and the power value of early delta frequency band (1-4 Hz, 160-300 ms) was larger, while the power values of late delta frequency band (1-4 Hz, 450-650 ms) and theta frequency band (4-8 Hz, 450-650 ms) were smaller in the high altitude group compared with those in low altitude group. The results suggested that long-term exposure to high altitude affected the spatial working memory ability of the migrants, which was reflected in the lack of attention resources in the later matching stage, decreased response inhibition ability and information maintenance ability, and thus resulted in impaired spatial working memory.


Subject(s)
Altitude , Brain , Electroencephalography , Humans , Memory, Short-Term , Reaction Time , Spatial Memory , Transients and Migrants
13.
Audiol., Commun. res ; 25: e2268, 2020. tab, graf
Article in Portuguese | LILACS | ID: biblio-1131787

ABSTRACT

RESUMO Objetivo Padronizar os parâmetros de latência e amplitude obtidos com o estímulo Ichirp de banda estreita, na pesquisa dos potenciais evocados auditivos de tronco encefálico nas frequências de 500 Hz, 1 kHz, 2 kHz e 4 kHz. Métodos O estudo foi realizado na Divisão de Saúde Auditiva do Hospital de Reabilitação de Anomalias Craniofaciais, da Universidade de São Paulo. Participaram 20 adultos ouvintes normais, na faixa etária de 18 a 35 anos. Todos os participantes foram submetidos à audiometria tonal limiar, logoaudiometria, imitanciometria e aos potenciais evocados auditivos de tronco encefálico, pesquisados com o estímulo Ichirp de banda estreita, nas frequências de 500 Hz, 1 kHz, 2 kHz e 4 kHz. Resultados Em todas as frequências avaliadas foi observada a função latência-intensidade, ou seja, o aumento na latência da onda V, na medida em que a intensidade do estímulo foi diminuída, bem como a diminuição na latência da onda V com o aumento da frequência avaliada. Além disso, verificou-se a redução na amplitude da onda V com a diminuição da intensidade do estímulo. Constatou-se o nível mínimo de resposta, em todas as frequências, em níveis inferiores aos valores sugeridos pela literatura como critério de normalidade no registro dos potenciais evocados auditivos de tronco encefálico de frequência específica, sendo os maiores valores nas frequências de 500 Hz e 1 kHz. Conclusão Foram obtidos os valores de referência de normalidade para os potenciais evocados auditivos de tronco encefálico em adultos ouvintes normais com o estímulo Ichirp, valores estes que podem contribuir para o aprimoramento do exame, na prática clínica.


ABSTRACT Purpose Standardize the latency and amplitude parameters using the narrow band Ichirp stimulus on Brainstem Auditory Evoked Potential (BAEP) at frequencies of 500 Hz, 1 kHz, 2 kHz and 4 kHz. Methods The study was performed at the Hospital for Rehabilitation of Craniofacial Anomalies (HRAC), Auditory Health Division, University of São Paulo (USP). Twenty normal hearing adults, aged between 18 and 35 years, were submitted to pure tone audiometry, speech audiometry, immittance and to BAEP with narrow band Ichirp stimulus at 500 Hz, 1 kHz, 2 kHz and 4 kHz frequencies. Results In all frequencies evaluated, the latency-intensity function was observed, that is, the increase in the latency of the V wave as the stimulus intensity was decreased, as well as the decrease in the latency of the V wave with the increase of the frequency. In addition, the reduction in the amplitude of the wave V was verified with the decrease of the intensity of the stimulus. The minimum response level, in all frequencies, was found to be lower than the values suggested in the literature as a criterion of normality in frequency - specific BAEP, with the highest values at frequencies of 500 Hz and 1 kHz. Conclusion Normal reference values to BAEP were obtained in normal hearing adults with the narrow band Ichirp stimulus, which may contribute to its improvement in clinical practice.


Subject(s)
Humans , Adolescent , Adult , Reaction Time/physiology , Reference Standards , Reproducibility of Results , Evoked Potentials, Auditory, Brain Stem/physiology
14.
Einstein (Säo Paulo) ; 18: eAO5225, 2020. tab
Article in English | LILACS | ID: biblio-1133730

ABSTRACT

ABSTRACT Objective To analyze the latency and the amplitude values of Mismatch Negativity and P300 cognitive potential in children with stuttering, with no auditory complaints, with auditory thresholds within the normality range, comparing them to the findings of a Control Group. Methods A cross-sectional study involving 50 children of both sexes, 15 with stuttering and 35 without stuttering, aged 6 to 11 years, with no diagnosis of ear pathology or other diseases. All children were submitted to peripheral audiological evaluation (meatoscopy, pure tone testing, speech audiometry, and acoustic immittance measures) and a central audiological evaluation (investigation of the Mismatch Negativity and P300 cognitive potential). For the evaluation of fluency, all children with stuttering had a specific history taken and were video recorded in a spontaneous speech. Afterwards, the transcription was done, followed by speech analysis to classify children according the severity of stuttering. Results There was a significant difference in the latencies of Mismatch Negativity and P300 cognitive potential, as well as in the amplitude of Mismatch Negativity. Conclusion There was a significant delay in the latencies of Mismatch Negativity and P300 cognitive potential, as well as increase in the amplitude of the Mismatch Negativity in children with stuttering when compared to children in the Control Group. Changes in the morphology of the waves were found in the Stuttering Group.


RESUMO Objetivo Analisar os valores de latência e amplitude do Mismatch Negativity e potencial cognitivo P300 em crianças com gagueira, sem queixas auditivas, com limiares auditivos dentro dos padrões de normalidade, comparando aos achados de um Grupo Controle. Métodos Estudo transversal, do qual participaram 50 crianças de ambos os sexos, sendo 15 com gagueira e 35 sem gagueira, entre 6 e 11 anos de idade, sem diagnóstico de patologias otológicas ou outras doenças. Todas as crianças realizaram avaliação audiológica periférica (meatoscopia, audiometria tonal, audiometria vocal e medidas de imitância acústica) e avaliação audiológica central (Mismatch Negativity e potencial cognitivo P300). Para avaliação da fluência, as crianças com gagueira realizaram anamnese específica, seguida da filmagem de uma fala espontânea, que foi transcrita e analisada quanto à severidade da gagueira. Resultados Houve diferença significativa nas latências do Mismatch Negativity e do potencial cognitivo P300, assim como na amplitude do Mismatch Negativity. Conclusão Verificou-se atraso nas latências do Mismatch Negativity e potencial cognitivo P300 nas crianças com gagueira, assim como aumento na amplitude do Mismatch Negativity, ao serem comparados com crianças do Grupo Controle. No Grupo com Gagueira foram igualmente identificadas alterações na morfologia das ondas.


Subject(s)
Humans , Male , Female , Child , Auditory Perception/physiology , Auditory Threshold , Stuttering/physiopathology , Evoked Potentials, Auditory/physiology , Reaction Time/physiology , Speech , Case-Control Studies , Cross-Sectional Studies
15.
Rev. chil. pediatr ; 90(6): 617-623, dic. 2019. tab, graf
Article in Spanish | LILACS | ID: biblio-1058192

ABSTRACT

INTRODUCCIÓN: Los exámenes habituales de coagulación evalúan distintos elementos de la hemostasia en forma par cial, y no traducen las interacciones celulares, lo que es especialmente sensible en pacientes críticos. Las técnicas viscoelásticas, como el tromboelastograma (TEG) muestran el proceso de coagulación completo, y están siendo evaluadas como exámenes de la coagulación global. OBJETIVO: determinar la correlación de los exámenes habituales de coagulación con los valores del TEG, en niños atendidos en una unidad de cuidados intensivos (UCI). PACIENTES Y MÉTODO: Se revisaron 238 TEG de pacientes <18 años, con evidencia de alteración de coagulación clínica y/o de laboratorio, hospitalizados en UCI. Se correlacionaron los valores de los parámetros del TEG con cada uno de los valores de los exámenes habituales de coagulación. Los exámenes se obtuvieron según protocolo, utilizando una muestra de sangre de 4,5 ml para TEG con equipo TEG® 5000 Thrombelastograph Hemostasis Sys tem, mediante un transductor electromagnético que permite la medición de la resistencia durante la formación y lisis del coágulo. El recuento de plaquetas se obtuvo utilizando método automatizado o microscopía con contraste de fase; el fibrinógeno, tiempo de protrombina y de tromboplastina parcial activada por métodos nefelométricos. RESULTADOS: 201 TEGs correspondientes a 59 pacientes. Se evidenció una correlación moderada a baja en todos los parámetros medidos. No se encontró co rrelación entre porcentaje de lisis del coágulo, ni firmeza del coágulo. CONCLUSIONES: Existe una baja correlación entre la información entregada por TEG y los exámenes de coagulación habituales, esto sugiere que el TEG aporta información diferente acerca del estado de coagulación de los pacientes críticos evaluados.


INTRODUCTION: Usual coagulation tests partially evaluate different elements of hemostasis, and do not translate cell interactions, which is an especially sensitive issue in critically ill patients. Viscoelastic measurement techniques, such as thromboelastogram (TEG) show the complete coagulation pro cess and are being evaluated as global coagulation tests. OBJECTIVE: To determine the correlation of the usual coagulation tests with the TEG values, in children treated in an intensive care unit (ICU). PATIENTS AND METHOD: We reviewed 238 TEGs of patients under 18 years of age, with evidence of clinical and/or laboratory coagulation alterations, who were hospitalized in the ICU. The TEG para meter values were correlated with each of the usual coagulation test values. The tests were obtained according to the protocol, using a 4.5 ml blood sample for TEG with TEG® 5000 Thrombelastograph Hemostasis System, through an electromagnetic transducer that allows the measurement of resis tance during the clot formation and lysis. Platelet count was obtained using an automated method or phase-contrast microscopy, and fibrinogen levels, prothrombin time, and partial thromboplastin time activated by nephelometric methods. RESULTS: 201 TEGs corresponding to 59 patients were re viewed. A moderate to low correlation was observed in all the measured parameters. No correlation was found between the percentages of clot lysis or clot firmness. CONCLUSIONS: There is a low corre lation between the information provided by TEG and the usual coagulation tests. This suggests that the TEG provides different information about the coagulation status of the evaluated critical patients.


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Adolescent , Thrombelastography/methods , Critical Illness , Platelet Count , Reaction Time , Time Factors , Blood Coagulation , Blood Coagulation Tests , Intensive Care Units, Pediatric , Retrospective Studies
16.
Acta bioquím. clín. latinoam ; 53(4): 511-524, dic. 2019. graf, tab
Article in Spanish | LILACS | ID: biblio-1124029

ABSTRACT

El objetivo de este trabajo fue establecer el impacto de la implementación de un sistema de gestión de calidad (SGC) en el desempeño del laboratorio de análisis clínicos del Hospital Materno Provincial. Se diseñaron diez indicadores de calidad (IC), que se midieron pre y posimplementación del sistema documental. Se encontró para el indicador solicitud médica incorrecta (SMI) una disminución de 11,2% a 6% cuando se implementó la gestión documental. Para el indicador omisión del diagnóstico (OD), el porcentaje bajó de 41,6% a 27,9% luego de la intervención. Se encontró un 5% de errores en ingreso al sistema informático del laboratorio (EI-SIL) en situación basal y 3,9% posimplementación, mientras que el indicador muestras mal remitidas (MMR) disminuyó de 3,1% a 1,9%. El 58% de los analitos disminuyó el índice de error total (IET) y el 80% aumentó el valor de sigma luego de la intervención. El 61% de los analitos disminuyó el valor de incertidumbre, mejorando de esta manera el desempeño de los métodos analíticos. El porcentaje de valores críticos (VC) comunicados al médico terapeuta antes de los 60 minutos aumentó del 20 al 54% después de la implementación de la gestión documental, mientras que el indicador reimpresión de informes (RI) disminuyó de 5,2 a 1,8%. El tiempo de respuesta (TAT) disminuyó de 164 a 125 minutos. La implementación de un SGC bajo los requisitos de normas internacionales mejoró el conocimiento y funcionamiento de los procesos del laboratorio clínico, evidenciado por la disminución de los errores en las etapas preanalítica, analítica y posanalítica.


The purpose of this study was to analyze the impact of implementing a quality management system (QMS) in the performance of a clinical laboratory of Hospital Materno Provincial. Ten quality indexes (QI) have been designed; they were measured before and after the implementation of the document management system (DMS). For the "incorrect medical application" index, there was a reduction from 11.2% to 6% when the DMS was implemented. For the "diagnostic omission" index, the percentage decreased from 41.6% to 27.9% after the implementation. Five per cent of mistakes were found in the admission of the laboratory computer system in the baseline state and 3.9% of the mistakes were found after implementation of the system. Meanwhile, the "incorrect sent samples" index decreased from 3.1% to 1.9%. Fifty eight per cent of the analytes decreased the total error index and 80% of them increased the sigma value after the intervention. Sixty one per cent of the analytes decreased the uncertainty value, thus improving the performance of analytical methods. The percentage of critical values communicated to the physician before the 60 minutes increased from 20% to 54% after the implementation of the DMS, while the "reprint of reports" index decreased from 5.2% to 1.8%. The turn around time (TAT) decreased from 164 to 125 minutes. The implementation of a QMS, under the requirements of international standards, improved the knowledge and the functioning of different processes of the clinical laboratory. This has been evidenced by the decrease of mistakes in the pre-analytical, analytical and post-analytical phases.


O objetivo deste trabalho foi estabelecer o impacto da implementação de um sistema de gestão de qualidade (SGC) no desempenho do laboratório de análises clínicas do Hospital Materno Provincial. Foram desenhados dez indicadores de qualidade (IQ), que foram medidos antes e depois da implementação do sistema documental. Foi achada uma diminuição de 11,2% para 6% no indicador solicitação médica incorreta, (SMI) quando se aplica a gestão documental. Para o indicador omissão do diagnóstico, a porcentagem baixou de 41,6% para 27,9% após a intervenção. Foram encontrados 5% de erros em entrada ao sistema informático do laboratório (EI-SIL) em situação basal e 3,9% pós-implantação, enquanto que o indicador amostras mal encaminhadas (AME) diminuiu de 3,1% para 1,9%. cincuenta e ocho por ciento dos analitos diminuíram o índice de erro total (IET) e 80% aumentou o valor de sigma após a intervenção. Sesenta e uno por ciento dos analitos diminuiu o valor de dúvidas, melhorando desta maneira o desempenho dos métodos analíticos. A porcentagem de valores críticos (VC) comunicados ao médico terapeuta antes dos 60 minutos aumentou de 20 para 54% depois da implementação da gestão documental, enquanto que o indicador reimpressão de relatórios diminuiu de 5,2 para 1,8%. O tempo de resposta diminuiu de 164 para 125 minutos. A implementação de um SGC sob os requisitos de normas internacionais melhorou o conhecimento e funcionamento dos processos do laboratório clínico, evidenciado pela diminuição dos erros nas etapas pré-analítica, analítica e pós-analítica.


Subject(s)
Organization and Administration , Reaction Time , Reference Standards , Clinical Laboratory Techniques , Quality Management , Indicators (Statistics) , Clinical Laboratory Services , Laboratories , Work , Computer Systems , Knowledge , State , Uncertainty , Diagnosis , Efficiency , Research Report , Missed Diagnosis , Hospitals
17.
Int. braz. j. urol ; 45(6): 1209-1215, Nov.-Dec. 2019. tab
Article in English | LILACS | ID: biblio-1056348

ABSTRACT

ABSTRACT Purpose: To compare the efficacy and safety of available selective serotonin reuptake inhibitors (SSRIs) in order to find the most effective drug with the least number of side effects in treatment of premature ejaculation (PE). Materials and Methods: This study was a randomized clinical trial. Four hundred and eighty patients with PE in the 4 groups referred to Imam Reza hospital Tehran, Iran from July 2018 to February 2019 were enrolled in the study. The patients received sertraline 50mg, fluoxetine 20mg, paroxetine 20mg and citalopram 20mg, every 12 hours daily. The intravaginal ejaculatory latency time (IELT) before treatment, fourth and eighth weeks after treatment was recorded by the patient's wife with a stopwatch. Results: Mean IELT before, 4 and 8 weeks after treatment in four groups were: sertraline 69.4±54.3, 353.5±190.4, 376.3±143.5; fluoxetine 75.5±64.3, 255.4±168.2, 314.8±190.4; paroxetine 71.5±69.1, 320.7±198.3, 379.9±154.3; citalopram 90.39±79.3, 279.9±192.1, 282.5±171.1 seconds, respectively. The ejaculation time significantly increased in all groups (p <0.05), but there was no significant difference between the groups (P=0.75). Also, there was no significant difference in drugs side effects between groups (p >0.05). The most common side effects were drowsiness and dyspepsia, which were not severe enough to cause discontinuation of the drug. Conclusions: All available SSRIs were effective and usually had no serious complications. In patients who did not respond to any of these drugs, other SSRI drugs could be used as a salvage therapy.


Subject(s)
Humans , Male , Adult , Aged , Young Adult , Citalopram/therapeutic use , Fluoxetine/therapeutic use , Serotonin Uptake Inhibitors/therapeutic use , Paroxetine/therapeutic use , Sertraline/therapeutic use , Premature Ejaculation/drug therapy , Reaction Time/drug effects , Time Factors , Treatment Outcome , Ejaculation/drug effects , Middle Aged
18.
Rev. chil. fonoaudiol. (En línea) ; 18: 1-20, nov. 2019. ilus, tab
Article in Spanish | LILACS | ID: biblio-1095114

ABSTRACT

El presente estudio aborda el impacto de la enfermedad de Parkinson en el procesamiento de información semántica durante una tarea de reconocimiento visual de palabras. Para ello, se comparó el rendimiento de un grupo de pacientes con Parkinson con el rendimiento de sujetos sin daño neurológico en dos experimentos. Se evaluaron los efectos de tiempo de presentación de un prime semántico directo (Experimento 1) y un prime semántico mediado orto-fonológicamente (Experimento 2). Además, se evaluó la influencia de la frecuencia léxica tanto del prime como la palabra target, sobre el acceso léxico. Los participantes estaban divididos en tres grupos (grupo clínico, grupo de control etario, y grupo de adultos jóvenes). Los tres grupos completaron una tarea de decisión léxica de tiempo de reacción en la modalidad go-no-go. Los participantes debían responder presionando una tecla del computador si el estímulo presentado en la pantalla era una palabra. En el caso contrario cuando era una pseudo palabra, los participantes no debían presionar ninguna tecla. Los resultados en base al número de respuestas correctas y los tiempos de reacción muestran dificultades de procesamiento semántico en el grupo clínico. Sin embargo, este grupo mostró ser sensible a la frecuencia de las palabras y los tiempos de presentación de estas. En su conjunto, los resultados son coherentes con la literatura existente, y contribuyen a comprender de mejor manera el déficit lingüístico presente en la enfermedad de Parkinson.


The present study addresses the incidence of Parkinson's disease in the processing of semantic information during visual word recognition tasks. In order to do so, the performance of a group of patients with Parkinson's was compared with the performance of subjects without neurological impairment in two experiments. We evaluate the effects of presentation time of a semantic prime (Experiment 1) and anortho-phonologically mediated semantic prime (Experiment 2), and the impact of the lexical frequency of both the prime and the target words. Participants divided into three groups (a clinical group, an age control group and a group of young adults), completed a reaction time lexical decision task in the go-no-go modality. They had to respond by pressing a computer key if the stimulus presented on the screen was a word. Otherwise, the participants should not press any key. The results, based on response accuracy and reaction times, show a semantic deficit in the clinical group, while this group was, nevertheless, sensitive to the frequency of the words and their presentation time. As a whole, the results are consistent with the existing literature, and contribute to a better understanding of the linguistic deficit present in Parkinson's disease.


Subject(s)
Humans , Parkinson Disease/physiopathology , Semantics , Speech/physiology , Language , Reaction Time , Memory
19.
Ciênc. cogn ; 24(1): 133-143, 15 nov. 2019. ilus, tab
Article in Portuguese | LILACS | ID: biblio-1048030

ABSTRACT

O Neurofeedback é uma técnica de treinamento psicofisiológico não invasivo que estimula o desenvolvimento da autorregulação psíquica e neurofisiológica. Além de ser aplicada com eficiência no tratamento de diversas demandas clínicas, o treinamento com neurofeedback tem sido adotado para modulação funcional do cérebro. O objetivo do presente estudo foi realizar uma revisão sistemática de estudos que tenham investigado efeitos do neurofeedback através de testes com medidas de tempo de reação. As consultas foram realizadas no período entre março e junho de 2018 nas bases de dados Pubmed (US National Library of Medicine) e Web of Science (Science Citation Index Expanded). Adotaram-se os seguintes descritores para a pesquisa ("neurofeedback") AND ("reaction time") AND ("cognitive" OR "cognition"). Após aplicação dos filtros para a seleção, foram encontrados 23 trabalhos, dentre os quais apenas 8 obedeceram aos critérios de elegibilidade. Alguns destes estudos mostram complexos delineamentos metodológicos. Verificou-se também que metade dos trabalhos validados se referem a adultos saudáveis, mas destaca-se também, em menor número, estudos com TDAH


Neurofeedback is a non-invasive psychophysiological training technique that stimulates the development of psychic and neurophysiological self-regulation. In addition to being effectively applied in the treatment of various clinical demands, neurofeedback training protocols have been adopted for functional neuromodulation. The present study aims to carry out a systematic review of studies that have investigated neurofeedback effects through tests measuring reaction times. Consultations of the Pubmed (US National Library of Medicine) and Web of Science (Science Citation Index Expanded) databases were carried out between March and June of 2018. The following descriptors were used in the consultation: ("neurofeedback") AND ("reaction time") AND ("cognitive" OR "cognition"). After applying filters for the selection, 23 papers were found, of which only 8 met the eligibility criteria. Some of these studies present complex methodological delineations. Half of the validated papers were found to refer to healthy adults, but it is worth highlighting studies with ADHD, even though those were found in a smaller number


Subject(s)
Reaction Time , Cognition
20.
Electron. j. biotechnol ; 38: 1-9, Mar. 2019. tab, graf
Article in English | LILACS | ID: biblio-1051273

ABSTRACT

BACKGROUND: Microbial oils produced by diverse microorganisms are being considered as alternative sources of triglycerides for biodiesel production. However, the standalone production of biodiesel from microorganisms is not currently economically feasible. In case of yeasts, the use of low-value nutrient sources in microbial production and the implementation of cost-efficient downstream processes could reduce costs and make microbial lipids competitive with other commodity-type oils in biodiesel production. Industrial biodiesel synthesis from oleaginous seeds is currently based on a multistep process. However, a simple process called in situ transesterification (ISTE), which takes place within the biomass without a previous lipid extraction step, is receiving increasing interest. In this work, the optimal conditions for an ISTE process to obtain biodiesel from previously selected oleaginous yeast (Rhodotorula graminis S1/S2) were defined using the response surface methodology (RSM). RESULTS: Using the RSM approach, the optimal conditions for the maximum yield with minimum reaction time included a methanol-to-biomass ratio of 60:1, 0.4 M H2SO4, and incubation at 70°C for 3 h. The optimized in situ process yield was significantly higher (123%) than that obtained with a two-step method in which fatty acids from saponifiable lipids were first extracted and then esterified with methanol. The composition of the fatty acid methyl ester mixture obtained from R. graminis S1/S2 by ISTE met Uruguayan standards for biodiesel. CONCLUSION: The characteristics achieved by the optimized method make microbial oil a potential alternative for biodiesel production from yeast at an industrial scale.


Subject(s)
Yeasts/metabolism , Biofuels , Reaction Time , Rhodotorula , Biomass , Environment , Esterification , Esters , Fatty Acids , Renewable Energy , Lipids , Methylation
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