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1.
J. Health Biol. Sci. (Online) ; 10(1): 1-7, 01/jan./2022. tab, ilus
Article in Portuguese | LILACS | ID: biblio-1411397

ABSTRACT

Objetivo: avaliar a eficiência de filtros de tratamento de água, usando carvão ativado de diferentes fontes de resíduo de biomassa. Métodos: trata-se de um estudo experimental, descritivo, de caráter quantitativo, realizado no Centro Universitário Católica de Quixadá, Ceará-Brasil, durante o período de janeiro a junho de 2018. Foram preparados filtros de carvão ativados e, posteriomente, sua eficiência no tratamento de água foi avaliada. Resíduos de descarte de madeira, a entrecasca do coco verde, a casca do fruto do caju e do colmo de bambu foram usados como fonte de matéria-prima. O filtro de tratamento de água foi montado, usando o método coluna de cromatografia, adicionando areia e algodão como outros meios filtrantes. Parâmentros físico-químicos foram utilizados na avaliação da eficiência dos filtros construídos. Resultados: a análise de componente principal selecionou dois componentes da qualidade de água, explicando 80,081% da variância total. O coeficiente de correlação cofenética de r=0.9572 indica que o dendograma estimado foi bom, considerando os parâmetros de qualidade da água. Entre os filtros, o bambu apresentou-se como melhor resposta entre filtros testados, sendo responsável pela redução de diversos fatores como cor, turbidez, dureza total e sódio. Conclusão: os fitros de carvão ativado derivado do descarte de madeira e da entrecasca do fruto do caju obtiveram pouca influência na melhoria da qualidade da água, em relação à amostra controle.


Objective: to evaluate the efficiency of water treatment filters using activated carbon from different sources of biomass residue. Methods: this is a descriptive experimental study of a quantitative nature carried out at the Centro Universitário Católica de Quixadá, Ceará-Brazil, during the period from January to June 2018. Activated carbon filters were prepared, and subsequently, their efficiency in water treatment was evaluated. Wood waste, green coconut husk, cashew nut shell, and bamboo stem were used as a source of raw material. The water treatment filter was assembled using the column chromatography method by adding sand and cotton as other filter media. Physicochemical parameters were used to evaluate the efficiency of the built filters. Results: principal component analysis selected two water quality components, explaining 80.081% of the total variance. The cophenetic correlation coefficient of r=0.9572 indicates that the estimated dendrogram was good, considering the water quality parameters. Among the filters, bamboo showed the best response among the filters tested, being responsible for the reduction of several factors such as color, turbidity, total hardness, and sodium. Conclusion: activated carbon filters derived from discarded wood and cashew nut shells had little influence on improving water quality compared to the control sample.


Subject(s)
Water , Charcoal , Water Purification , Reference Standards , Therapeutics , Waste Products , Water Quality , Filters , Principal Component Analysis
2.
Rev. Ciênc. Plur ; 8(3): 28520, out. 2022. ilus, tab
Article in Portuguese | LILACS, BBO | ID: biblio-1399335

ABSTRACT

Introdução:Em dezembro de 2019 na China, o SARS-CoV-2 foi identificado e declaradocomopandemiapelaOrganização Mundial da Saúde.Suatransmissibilidade entrehumanos e evoluçãocomestabilidade clínicaehemodinâmica, aumentam o risco dodesenvolvimento delesões por pressãonos pacientes mais críticos.Objetivo:Identificar os principais cuidados hospitalares para manter a integridade da pele nos pacientes com COVID-19propensos a lesão por pressão. Metodologia:Estudo descritivo do tipo revisão integrativa realizado nas bases: Literatura Latino-Americana de Ciências da Saúde, Base de Dados de Enfermagem,Scientific Eletronic Library OnlineeBiblioteca Nacional de Medicina dos Estados Unidoscom osdescritores COVID-19, Lesão por pressão, Assistência ao pacienteePadrões de referência. Os critérios de inclusãoforamtextos completosdisponíveis gratuitamente, publicados entre 2019 e2021, que compartilhassem da temáticaem adultos e/ou idosos.Foramexcluídos artigos incompletos,plataformas pagas, cartae notas editor, reflexões e os artigos duplicados foram contabilizados uma vez, o idioma de origem não foi fator excludente.Resultados:Foram identificados 398 artigos potencialmente relevantes e 7 foram selecionados. As principais práticas relacionadas a prevenção de lesões por pressão em pacientes com COVID-19 apontamintervenções como o uso de checklist, avaliação periódica da pele,definiçãodo risco de desenvolvimento de lesão por pressão, mudança de decúbito conforme tolerância do paciente, uso de superfície para redistribuição de peso, cobertura profilática multicamadase controle da umidade da pele. Conclusões:As principais práticasparaevitar aslesões por pressãonos pacientes com COVID-19 no ambiente hospitalarestãoassociadas como cuidado direto ou indiretamente ligados a pele,adoção de medidas preventivas e sistemáticas dentro da realidade clínica e hemodinâmica dos pacientes (AU).


Introduction:In December 2019, in China, SARS-CoV-2 virus was identified and a pandemic was declared by the World Health Organization. Its transmissibility among humans and evolution with clinical and hemodynamic stability increases the risk of developingpressure injuries in the most critical patients.Objective:To identify the main hospital care to maintain skin integrity in COVID-19patients prone to pressure injuries.Methodology:A descriptive study of integrative review carried out in the following bases: Latin-American Health Sciences Literature, Nursing Database, Scientific Electronic Library Online and the National Library of Medicine of the United States, with the descriptors COVID-19, Pressure Injuries, Patient Care and Benchmarks. Inclusion criteria were full texts available for free, published between 2019 and 2021, which shared the subject matter in adults and/or elderly people. Incomplete articles, paid platforms, editor'sletter and notes, and reflections were excluded; duplicate articles were counted once. The source language was not an excluding factor.Results:398 potentially relevant articles were identified, 7 were selected. The main practices related to the prevention of pressure injuries in patients with COVID-19 point to interventions such as the use of checklists, periodic skin assessment, definition of the risk of developing pressure injuries, change of decubitus according to the patient's tolerance, use of surface for weight redistribution, multi-layer prophylactic coverage and skin moisture management.Conclusions:The main practices to avoid pressure injuries in patients with COVID-19in the hospital environment are associated with care directly or indirectly linked to the skin, adoption of preventive and systematic measures within the clinical and hemodynamic reality of patients (AU).


Introducción: Endiciembre de 2019, en China, el SARS-CoV-2 fue identificado y declarado pandemia por laOrganización Mundial de la Salud. Su transmisibilidad entre humanos y la evolución conestabilidad clínica yhemodinámica aumentan el riesgo de desarrollar lesiones por presión en lospacientes más críticos. Objetivo:Identificar los principales cuidados hospitalarios para mantener la integridad de la piel en pacientes con COVID-19propensos a lesiones por presión. Metodología:Estudio descriptivo del tipo "revisiónintegradora" realizado em las bases de datos: Literatura Latinoamericana de Ciencias de la Salud, Base de Datos de Enfermería, ScientificEletronic Library Online (Biblioteca Electrónica Científica en Línea) y Biblioteca Nacional de Medicina de los EstadosUnidos con los identificadores COVID-19, Lesión por Presión, Atención al Paciente y Estándares de Referencia. Loscriterios de inclusión fueron textos completos disponiblesde forma gratuita, publicados entre el 2019 y 2021, quecompartieron el tema en adultos y/o ancianos.Se excluyeronlos artículos incompletos, las plataformas pagadas,las cartas y las notas del editor y las reflexiones. Los artículos duplicados se contaron una vez. El idioma de origenno fue un factor de exclusión. Resultados:Se identificaron un total de 398 artículos potencialmente relevantes, 7fueron seleccionados. Las principales prácticasrelacionadas con la prevención de lesiones por presión em pacientes con COVID-19 apuntan a intervenciones como el uso de checklist, evaluación periódica de la piel,riesgo de lesión por presión, cambio de decúbito según tolerancia del paciente, uso desuperficie para redistribución de peso, cobertura profiláctica multicapa y control de la humedad de la piel.Conclusiones:Lasprincipales prácticas para evitar lesiones por presión en pacientes con COVID-19 en el ámbitohospitalario se asocian con cuidados directa o indirectamente vinculados a la piel, adopción de medidaspreventivas y sistemáticas dentro de la realidad clínica y hemodinámica de los pacientes (AU).


Subject(s)
Reference Standards , Pressure Ulcer/nursing , Pressure Ulcer/prevention & control , Patient Care , COVID-19 , Risk Factors , Nursing Care
3.
Lima; Perú. Ministerio de Salud. Instituto Nacional de Salud. Centro Nacional de Salud Pública; 1 ed; Set. 2022. 12 p. ilus.(Serie Nota Técnica, 037).
Monography in Spanish | LILACS, LIPECS, MINSAPERU, INS-PERU | ID: biblio-1402629

ABSTRACT

La presente publicación describe las recomendaciones internacionales emitidas a la fecha, respecto al uso de mascarillas en la población general y si éstas señalaban usar doble mascarilla, una sola mascarilla o sólo un respirador (KN95 o N95). De la revisión de 11 documentos emitidos por organismos y autoridades sanitarias internacionales, se identificó que tanto el uso de una mascarilla o un respirador (incluyendo N95 o KN95) ha sido incluido en las recomendaciones para su uso en población general. Independientemente del dispositivo, se ha coincidido en que lo fundamental es el uso adecuado del mismo, que se ajuste bien a la cara, que se pueda usar constantemente y esté disponible. Las opciones, en orden descendente de acuerdo al nivel de protección son: respiradores aprobados por NIOSH, respiradores tipo KN95 con buen ajuste, mascarillas quirúrgicas desechables y en último lugar las mascarillas de tela de múltiples capas con buen ajuste y varilla nasal. La OMS, el CDC de Estados Unidos, el CDC de la Unión Europea y el gobierno de Canadá han precisado los estándares que deben ser cumplidos


Subject(s)
Reference Standards , Ventilators, Mechanical , Protective Factors , COVID-19 , Masks , N95 Respirators
4.
Lima; Perú. Ministerio de Salud. Dirección General de Intervenciones Estratégicas en Salud Pública. Dirección de Salud Mental; 1 ed; Ago. 2022. 34 p. ilus.
Monography in Spanish | LILACS, LIPECS, MINSAPERU | ID: biblio-1392066

ABSTRACT

La presente publicación describe los parámetros técnicos estandarizados, para la evaluación de la afectación psicológica de personas, en caso de haber sido víctimas de violencia contra las mujeres y los integrantes del grupo familiar y para contribuir a la recuperación integral y oportuna de las personas víctimas de violencia contra las mujeres e integrantes del grupo familiar que acuden a las Instituciones Prestadoras de Servicios de Salud (IPRESS)


Subject(s)
Reference Standards , Stress, Psychological , Mental Health , Domestic Violence , Risk Assessment , Victims Identification , Psychosocial Impact , Violence Against Women
5.
Article in Spanish | LILACS-Express | LILACS, CUMED | ID: biblio-1410309

ABSTRACT

En el presente trabajo se realiza la estandarización del procedimiento espectrofotométrico de determinación de polisacárido capsular e intermedios de Neisseria meningitidis serogrupo X, mediante la determinación de los grupos fosfodiéster presentes en su estructura, por el método de Chen. Se realizó un análisis de los siguientes criterios para la estandarización: linealidad, precisión (repetibilidad y precisión intermedia) y exactitud. Se demostró mediante el diseño experimental y los procedimientos estadísticos empleados que el método es lineal (r > 0,99), el coeficiente de variación del factor respuesta < 5 por ciento, la desviación estándar relativa de la pendiente < 2 por ciento, no existiendo diferencia estadísticamente significativa entre el intercepto de la ecuación con respecto a cero; exacto, porque no existe diferencia estadísticamente significativa entre la concentración determinada en un material de trabajo y su concentración nominal; también demostró ser repetible, pues el coeficiente de variación de las concentraciones de la muestra evaluada (2,44; 2,43; 0,88 por ciento para las concentraciones bajas, medias y altas, respectivamente) es inferior al 3 por ciento y no existen diferencias estadísticamente significativas entre las medias de los resultados obtenidos por dos analistas, evaluados durante cuatro días a tres niveles de concentración. La precisión intermedia es satisfactoria(AU)


The present work comprises the standardization a spectrophotometric procedure for assessing Neisseria meningitidis, serogroup X capsular polysaccharide and their intermediates of modification, the phosphodiesters groups present in its structure, based on Chen method. An analysis of the following standardization criteria was performed: linearity, precision (repeatability and intermediate precision) and accuracy. It was demonstrated through the experimental design and the statistical procedures used that the method is linear (r > 0.99), the coefficient of variation of the response factor < 5 percent, the relative standard deviation of the slope < 2 percent, with no statistically significant difference between the intercept of the equation with respect to zero; exact, because there is no statistically significant difference between the concentration determined in a work material and its nominal concentration; it also proved to be repeatable, because the coefficient of variation of the concentrations of the sample (2.44; 2.43; 0.88 percent for low, medium and high concentrations respectively) is less than 3 percent and there is no statistically significant difference between the means of the results obtained by two analysts, evaluated for four days at three concentration levels. Its intermediate precision was satisfactory(AU)


Subject(s)
Humans , Male , Female , Reference Standards , Spectrophotometry/methods , Virulence Factors , Meningococcal Infections/diagnosis , Meningococcal Infections/epidemiology , Phosphodiesterase Inhibitors
6.
RECIIS (Online) ; 16(2): 298-316, abr.-jun. 2022. tab, ilus
Article in Portuguese | LILACS | ID: biblio-1378362

ABSTRACT

Este artigo apresenta reflexões acerca do conjunto de ações do projeto ArboControl em Roraima relatadas, neste estudo, a partir das experiências e práticas de combate à desinformação do Amazoom ­ Observatório Cultural da Amazônia e do Caribe. Para a melhor compreensão das formas de fazer apresentamos, neste estudo, o contexto em que elas ocorrem; os aspectos gerais que pautaram a criação do Amazoom e a sua vinculação à iniciativa nacional do ArboControl; os objetivos e as múltiplas dimensões das práticas comunicativas executadas no âmbito do projeto; os conceitos e as ideias que movimentamos no exercício desse fazer; os métodos e as técnicas que utilizamos; e os principais produtos, os seus processos e os resultados parciais alcançados até o momento. Enfatizamos, a partir das práticas realizadas e do material analisado, a importância da produção de conteúdos próprios (apropriados e apropriáveis), inspirados nos preceitos da educomunicação, capazes de acionar linguagens híbridas, narrativas múltiplas e mais efetivas, na prevenção, no monitoramento e no controle das arboviroses (e de seus vetores).


This article presents some thoughts about the set of actions of the ArboControl project in Roraima, reported in this study, based on the experiences and practices in fighting misinformation by Amazoom ­ Cultural Observatory of the Amazon and the Caribbean. For a better understanding of these ways of doing, we present, in this study, the context in which they occur; the general aspects that guided the creation of Amazoom and its connection to the national initiative of ArboControl; the objectives and the multiple dimensions of the communicative practices implemented in the scope of the project; the concepts and ideas that we put into motion in these practices; the methods and techniques that we employed; and the main products, their processes and partial results achieved so far. We emphasize, based on the accomplished activities and their analyzed material, the importance of producing our own content (appropriate and appropriable), inspired by the principles of educommunication, which are able to engage in hybrid languages, narratives that are multiple and more effective in the prevention, monitoring and control of arboviruses (and their vectors).


Este artículo presenta reflexiones sobre el conjunto de acciones del proyecto ArboControl en Roraima, relatado, en este estudio, a partir de las experiencias y prácticas de Amazoom ­ Observatorio Cultural de la Amazonia y el Caribe ­ en la lucha contra la desinformación. Para una mejor comprensión de estas formas de hacer, presentamos, en este estudio, el contexto en el que se producen; los aspectos generales que guiaron la creación de Amazoom y su vinculación a la iniciativa nacional de ArboControl; los objetivos y las múltiples dimensiones de las prácticas comunicativas ejecutadas en el ámbito del proyecto; los conceptos e ideas que movemos en el ejercicio de este hacer; los métodos y técnicas que utilizamos; y los principales productos, sus procesos y resultados parciales alcanzados hasta el momento. A partir de las prácticas realizadas y del material analizado, destacamos la importancia de la producción de contenidos propios (adecuados y apropiados), inspirados en los preceptos de la educomunicación, capaces de activar lenguajes híbridos, narrativas múltiples y más eficaces en la prevención, el seguimiento y el control de las arbovirosis (y sus vectores).


Subject(s)
Humans , Communication , Health Communication , Disinformation , Arbovirus Infections , Reference Standards , Information Dissemination , Projects , Mass Media
8.
Hematol., Transfus. Cell Ther. (Impr.) ; 44(2): 218-224, Apr.-June 2022. tab
Article in English | LILACS | ID: biblio-1385064

ABSTRACT

Abstract Introduction The novel SARS-CoV-2 infection has been spreading around the world since January 2020 causing the Corona Virus Disease 2019. Leukopenia, lymphopenia and hypercoagulability with elevated D- Dimers have been described in COVID-19 patients to date. This study aimed to clarify if some blood parameters can be used as biomarkers to facilitate diagnosis and establish prognosis. Methods: We selected patients who had tested positive for SARS-CoV-2 and had had a hemogram performed between the March 15 and April 15, 2020. Socio-demographic and analytical data were obtained from 274 patients at admission in two Portuguese public hospitals. We then analyzed the hemogram parameters at admission in the intensive care and collected data on patient survival during the SARS-CoV-2 disease follow-up. The data were analyzed using appropriate statistical tests. Results: Patients requiring the intensive care unit (ICU) present an increase in leukocytes and neutrophils (+3.1 × 109/L and +6.4 × 109/L, respectively), a lymphocyte decrease and a platelet rise (-1.6 × 109/L and +60.8 × 109/L, respectively). The erythrocytes, hemoglobin and median globular volume tend to decrease (-0.5 × 1012, - 1.2 g/dL; -3 fL, respectively). The lactic acid dehydrogenase (LDH) at admission was significantly higher (+58.1 U/L). The age, sex, platelets, lymphocyte count neutrophil counts, neutrophil/lymphocyte ratio, erythrocytes and cell hemoglobin concentration mean (CHCM) are independently associated with mortality (odds ratio (OR) = 0.046, p < 0.001; OR = 0.2364, p= 0.045; OR = 9.106, p= 0.001; OR = 0.194, p= 0.033; OR = 0.062, p= 0.003; OR = 0.098, p= 0.002; OR = 9.021, p < 0.001; OR = 7.016, p= 0.007, respectively). Conclusion The hematological data at admission in the health care system can predict the mortality of the SARS-CoV-2 infection and we recommend its use in the clinical decisions and patient prognosis evaluation.


Subject(s)
Humans , Male , Female , Child , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Young Adult , SARS-CoV-2 , COVID-19/mortality , Hematologic Diseases , Reference Standards , Blood Cell Count , Biomarkers , Mortality , Thrombophilia , Intensive Care Units , Leukopenia , Lymphopenia
9.
Article in Spanish | LILACS-Express | LILACS, CUMED | ID: biblio-1408440

ABSTRACT

Introducción: Las mutaciones del gen que codifica para el factor de la tirosina quinasa 3 (FLT3) son de especial importancia en la leucemia mieloide aguda debido a que sirven de guía para la confirmación del diagnóstico, la estimación del pronóstico y la toma de decisiones terapéuticas. Entre las alteraciones más importantes está la duplicación interna en tándem (FLT3-ITD). Objetivo: Exponer los aspectos más relevantes respecto al biomarcador FLT3-ITD en el contexto de la leucemia mieloide aguda. Métodos: Se realizó una búsqueda de artículos científicos actualizados en los idiomas inglés y español, en PubMed, EMBASE, Google Scholar y SciELO. Se seleccionaron artículos publicados en los últimos cinco años. Se revisaron los aspectos más relevantes sobre el biomarcador en el contexto de la leucemia mieloide aguda, su base biológica, el impacto del tamaño de los fragmentos y la carga alélica en la estimación del pronóstico de los pacientes, las nuevas estrategias terapéuticas y los retos en cuanto a los métodos de laboratorio para su diagnóstico. Análisis y síntesis de la información: Más allá de la positividad o no de dicho biomarcador, el tamaño de la duplicación interna en tándem, así como la carga alélica -determinada por la razón alelo mutado/alelo salvaje-, podrían tener un gran impacto en el pronóstico. Sin embargo, persisten diferencias en los criterios para establecer los algoritmos de predicción del riesgo, el punto de corte a utilizar como referencia y el protocolo de laboratorio específico para un estudio más detallado del biomarcador. Conclusiones: La comunidad científica necesita seguir trabajando en el esclarecimiento de la utilidad práctica de estos parámetros, validándolos en series amplias y diversas epidemiológicamente. Se debe determinar el punto de corte exacto para comparar la razón y estandarizar los métodos de laboratorio más adecuados y factibles para su estudio(AU)


ABSTRACT Introduction: Mutations in the tyrosine kinase 3 gene (FLT3) are of special importance in acute myeloid leukemia because they serve as a guide to confirm the diagnosis, estimate the prognosis, and make therapeutic decisions in the patient. Internal tandem duplication (FLT3-ITD) is the most important alteration of this gene. Objective: To present the most relevant aspects regarding the FLT3-ITD biomarker in the context of acute myeloid leukemia. Methods: a search was carried out for updated scientific articles, in English and Spanish, in PubMed, EMBASE, Google Scholar and SciELO. Articles published in the last five years were selected. The most relevant aspects of the biomarker in the context of acute myeloid leukemia, its biological basis, the impact of the size of the fragments and the allelic load in the estimation of the prognosis of the patients, the new therapeutic strategies and the challenges in regarding the laboratory methods for its diagnosis. Information analysis and synthesis: Beyond the biomarker positivity or not, the size of the ITD, as well as the allelic ratio determined by the mutated allele / wild-type allele, could have a great impact on the prognosis of patients. However, differences persist in the criteria for establishing risk prediction algorithms, the cut-off point to be used as a reference, and the specific laboratory protocol for a more detailed study of the biomarker. Conclusions: The scientific community needs to continue working to clarify the practical utility of these parameters, validating them in broad and epidemiologically diverse series. The exact cut-off point should be determined as a reference to compare the relationship and standardize the most suitable and feasible laboratory methods for its study(AU)


Subject(s)
Humans , Reference Standards , Biomarkers , Leukemia, Myeloid, Acute , Residence Characteristics
10.
Rev. Inst. Adolfo Lutz ; 81(Único): e37165, mar.1, 2022. ilus
Article in English | LILACS, ColecionaSUS, SES-SP, VETINDEX, CONASS, SESSP-ACVSES, SESSP-IALPROD, SES-SP, SESSP-IALACERVO | ID: biblio-1393020

ABSTRACT

The standardization and validation of a multiplex assay requires the combination of important parameters such as sensitivity and specificity, acceptable levels of performance, robustness, and reproducibility. We standardized a multiparametric Dot-blot aimed at the serological screening of paracoccidioidomycosis, histoplasmosis, and aspergillosis. A total of 148 serum were evaluated: 10 from healthy subjects, 36 from patients with paracoccidioidomycosis, 62 from patients with histoplasmosis, and 40 from patients with aspergillosis. It was found that the multiparametric Dot-blot showed a high percentage of cross-reactivity. However, when evaluated individually, in the serological screening of histoplasmosis, a good performance was observed when compared to the double immunodiffusion assay, considered the gold standard test, with 100% co-positivity and 83.3% co-negativity. The performance of serological screening for aspergillosis was not satisfactory when compared to double immunodiffusion, showing 71.4% co-positivity and 100% co-negativity. The evaluation of the stability of nitrocellulose membranes showed that membranes sensitized with H. capsulatum antigen remained stable for 90 days and those sensitized with A. fumigatus antigen for 30 days. We conclude that the use of crude antigens was not suitable for the standardization of the multiparametric Dot-blot assay, due to the high cross-reactivity, and that further tests should be performed with purified proteins (AU).


A padronização e validação de um ensaio multiplex requer a combinação de parâmetros importantes, como sensibilidade e especificidade, níveis aceitáveis de desempenho, robustez e reprodutibilidade. Este trabalho padronizou um Dot-blot multiparamétrico visando a triagem sorológica da paracoccidioidomicose, histoplasmose e aspergilose. Foram avaliadas 148 amostras de soro: 10 de indivíduos saudáveis, 36 de pacientes com paracoccidioidomicose, 62 de pacientes com histoplasmose e 40 de pacientes com aspergilose. Verificou-se que o Dot-blot multiparamétrico apresentou elevado percentual de reatividade cruzada. Entretanto, quando avaliado individualmente, na triagem sorológica da histoplasmose observou-se bom desempenho quando comparado ao ensaio de imunodifusão dupla, considerado o teste padrão ouro, com 100% de co-positividade e 83,3% de co-negatividade. O desempenho da triagem sorológica da aspergilose não foi satisfatório quando comparado a imunodifusão dupla, apresentando 71,4% de co-positividade e 100% de co-negatividade. A avaliação da estabilidade das membranas de nitrocelulose mostrou que membranas sensibilizadas com antígeno de H. capsulatum permaneceram estáveis por 90 dias e as sensibilizadas com antígeno de A. fumigatus, por 30 dias. Concluímos que o uso de antígenos brutos não foi adequado para a padronização do ensaio de Dot-blot multiparamétrico, devido ao alto índice de reatividade cruzada, e que novos testes devem ser realizados com proteínas purificadas (AU).


Subject(s)
Paracoccidioidomycosis , Aspergillosis , Reference Standards , Immunologic Tests , Public Health , Methodology as a Subject , Histoplasmosis , Mycoses/diagnosis
11.
Arch. latinoam. nutr ; 72(1): 60-71, mar. 2022. ilus
Article in Spanish | LILACS, LIVECS | ID: biblio-1368374

ABSTRACT

Los Trastornos de la Conducta Alimentaria (TCA) son una enfermedad mental grave, causante de morbilidad física y psicosocial. Esta enfermedad tiene una mayor prevalencia entre mujeres jóvenes, y en población deportista. La terapia cognitiva conductual (TCC) es el tratamiento actual más adecuado para este tipo de trastornos, no obstante, cada vez son más los programas que incluyen pautas de ejercicio físico (EF) y Terapia Nutricional (TN) para el tratamiento de los TCA. Objetivo. Realizar una revisión sistemática exploratoria de la literatura que permita conocer el estado actual de los programas de intervención a través del EF y la TN para el tratamiento de los TCA. Materiales y métodos. Se realizó una búsqueda y recopilación de documentos científicos mediante un modelo de acumulación de datos y selección de estudios, en la que se utilizaron las bases de datos informatizadas SCOPUS, Web of Science, y PubMed. En todas las bases de datos consultadas, se empleó la misma frase de búsqueda. Para acotar los resultados, se introdujeron una serie de criterios de inclusión y exclusión. Resultados. La revisión contó con cinco documentos relacionados con la temática de estudio, que cumplían los criterios de inclusión. Conclusión. Las intervenciones con EF y TN para el tratamiento de los TCA suponen una reducción en la severidad de la sintomatología de los pacientes. Estos programas se muestran como una herramienta terapéutica alternativa o complementariaa la terapia convencional. Se requieren más estudios que combinen programas de intervención de EF y TN dirigidos a pacientes con TCA(AU)


Eating Disorders (ED) are a severe mental illness that causes physical and psychosocial problems. This illness has a higher prevalence among young women, and between athletes. cognitive behavioural therapy (CBT) is the current treatment for this type of disorder. However, more and more programs are including physical exercise (PE) and nutritional therapy (TN) for eating disorders treatment. Objective. To carry out an exploratory systematic review of the literature that allows us to know the current state of intervention programs through physical exercise and nutritional therapy for the treatment of eating disorders. Materials and methods. For the reference search thesame search phrase was used. The terms were entered in English in the following computerized databases: SCOPUS, Web of Science, and PubMed. To limit the search, four inclusion criteria were introduced. Results. The review included five scientific articles related to the study topic, which met the inclusion criteria. Conclusion. Intervention programs for the treatment of eating disorders that include physical exercise and nutritional therapy are shown as an alternative or complementary tool to conventional therapy. These programs involve a reduction in the severity of ED symptoms and an improvement in anthropometric parameters and physical condition. More studies that combine PE and TN programs for people with ED are required(AU)


Subject(s)
Humans , Exercise , Anorexia Nervosa , Feeding and Eating Disorders , Cognitive Behavioral Therapy , Nutrition Therapy , Bulimia Nervosa , Mental Disorders , Self Concept , Body Image , Morbidity , Reference Standards
12.
Más Vita ; 4(1): 211-220, mar. 2022. tab
Article in Spanish | LILACS, LIVECS | ID: biblio-1372054

ABSTRACT

El parto constituye un acontecimiento extraordinario en la vida de la mujer, dado precisamente, por ser la culminación del embarazo humano y al unísono, el inicio de una nueva vida, razón por la que se le atribuye especial interés a nivel universal. Objetivo: Analizar el cumplimiento de estándares e indicadores de parto y nacimiento humanizado en el Centro de Salud Tipo C. Materiales y Métodos: Estudio observacional, descriptivo, prospectivo, de corte transversal. Con una población total de pacientes atendidas en el Servicio de Centro Obstétrico del Instituto "Velasco Ibarra", en Machala Ecuador, de enero a diciembre del 2020. Resultados: 743 pacientes tuvieron control prenatal con más de 5 sesiones, el 100% de los partos fue espontaneo, con ruptura anteparto, sin inducción, en su mayoría con las semanas completas. En cuanto a la presentación del parto 996 casos fueron de presentación cefálica. 862 pacientes no tuvieron acompañantes, sino, el grupo sanitario, médicos y enfermeras y solo a 125 se le permitió tener a su pareja. En cuanto a la posición del parto, 908 estuvieron en posición de litotomía (ginecológica), en cuanto a la analgesia, solo 267 y ninguna requirió anestesia, así como tampoco requirieron sangre, sulfato, hierro ni anticonceptivos postparto. Conclusiones: Se precisa la inclusión del componente humanizador e integral para la concepción del parto como un proceso natural y fisiológico, con la combinación científico-humanista en el logro de una atención con calidad y calidez, donde la mujer ecuatoriana protagonice su proceso de parto como un sujeto de cuidado y no como objeto del mismo(AU)


Childbirth is an extraordinary event in a woman's life, given precisely because it is the culmination of human pregnancy and at the same time the beginning of a new life, which is why special interest is attributed to it at a universal level. Objective: To analyze compliance with humanized childbirth and delivery standards and indicators in the Type C Health Center. Materials and Methods: Observational, descriptive, prospective, cross-sectional study. With a total population of patients treated at the Obstetric Center Service of the "Velasco Ibarra" Institute, in Machala Ecuador from January to December 2020. Results: 743 patients had prenatal control with more than 5 sessions, 100% of deliveries were spontaneous with antepartum rupture, without induction and almost all with complete weeks. And in 3, regarding the presentation of delivery, 996 cases were of cephalic presentation. 862 patients did not have companions, but the health group, doctors and nurses and only 125 were allowed to have their partner. As for the position of delivery, 908 were in the lithotomy (gynecological) position, as for analgesia only 267 and none required anesthesia, nor did they require blood, sulfate, iron, or postpartum contraceptives. Conclusions: the inclusion of the humanizing and integral component is required for the conception of childbirth as a natural and physiological process, with the scientific-humanistic combination in achieving care with quality and warmth, where the Ecuadorian woman is the protagonist of her birth process as a a subject of care and not as its object(AU)


Subject(s)
Humans , Female , Pregnancy , Reference Standards , Humanizing Delivery , Reproductive Health , Women's Rights , Pregnancy , Health Personnel , Obstetric Violence
13.
Más Vita ; 4(1): 165-178, mar. 2022. tab
Article in Spanish | LILACS, LIVECS | ID: biblio-1372280

ABSTRACT

Se trata de la recopilación de información sobre estudios que reflejan la situación nutricional en Ecuador, y las comparaciones entre los percentiles ecuatorianos y los que sugiere la Organización Mundial de la Salud (OMS). Estudios refieren que este tipo de comparación difiere de las realidades de un país pues presenta diferente ubicación geográfica y por sus rasgos culturales, que difieren ancestralmente se presentan divergencias entre la alimentación, estilos de vida, bases socioeconómicas, rasgos antropométricos y otras variables que influyen y que han obligado a crear sus propios estándares de comparaciones. Objetivo: Describir la situación nutricional entre los percentiles ecuatorianos y la OMS en adolescentes de 12 años. Materiales y método: Es del tipo cualitativa, descriptiva, donde se recopila información relevante vinculada al descriptor en estudio, por eso la modalidad es tipo documental y descriptiva, transversal y observacional porque se le y observa información relevante de momento y se describe y señalan procedimientos como modelos para otras investigaciones. Resultados: Ecuador como país latinoamericano refleja una situación alimentaria y nutricional de amplio potencial productivo, de grandes oportunidades y capacidades socioeconómicas, necesarios para dar respuestas a las exigencias nutricionales de su población. Sin embargo, la información sobre el estado nutricional de la población infantil refleja el desarrollo del país, con una reducción significativa de la prevalencia de retardo de crecimiento, que prevalecen mucho más en grupos indígenas, por problemas sociales: mortalidad infantil, pobreza, indigencia y analfabetismo. Conclusiones: Estimar valores de desnutrición y sobrepeso a través de comparaciones por los percentiles internacionales (WHO) y los de Estados Unidos no reflejan la realidad de una población que difiere en todo con la de esos estándares comparativos. Por ello el esfuerzo de estudios por crear sus propios estándares nacionales es loable y muestra las realidades de una población(AU)


This is the collection of information on studies that reflect the nutritional situation in Ecuador, and comparisons between Ecuadorian percentiles and those suggested by the World Health Organization (WHO). Studies report that this type of comparison differs from the realities of a country because it has different geographical location and its cultural features, which differ ancestrally, there are divergences between food, lifestyles, socioeconomic bases, anthropometric traits and other variables that influence and that have forced to create their own standards of comparisons. Objective: To describe the nutritional situation between the Ecuadorian and WHO percentiles in 12-year-old adolescents Materials and methods: It is of the qualitative, descriptive type, where relevant information linked to the descriptor in study is collected, so the modality is documentary and descriptive, transversal and observational because relevant information is observed at the moment and procedures are described and indicated as models for another research. Results: Ecuador as a Latin American country reflects a food and nutritional situation with ample productive potential, great opportunities and socioeconomic capacities, necessary to respond to the nutritional demands of its population. However, information on the nutritional status of the child population reflects the development of the country, with a significant reduction in the prevalence of growth retardation, which is much more prevalent in indigenous groups, due to social problems: infant mortality, poverty, indigence and illiteracy. Conclusions: Estimating values of malnutrition and overweight through comparisons by the international percentiles (WHO) and those of the United States do not reflect the reality of a population that differs in everything with that of these comparative standards. That is why the effort of studies to create their own national standards is laudable and shows the realities of a population(AU)


Subject(s)
Reference Standards , Body Weights and Measures , Nutritional Status , Life Style , Nutritional Requirements , Socioeconomic Factors , World Health Organization , Prevalence , Growth and Development
14.
Rev. ciênc. méd., (Campinas) ; 31: e225379, 17 fev. 2022. ilus, tab
Article in Portuguese | LILACS | ID: biblio-1410398

ABSTRACT

O objetivo deste estudo foi identificar e reunir os principais achados disponíveis no começo da pandemia, acerca das alterações laboratoriais de pacientes internados com COVID-19 e discutir a predominância dessas alterações na gravidade do curso da doença. Trata-se de uma revisão sistemática de literatura, restringida a publicações até abril de 2020, utilizando as bases de dados Lilacs e Pubmed. Um total de 381 publicações foram encontradas nas bases de dados consultadas e destas, 17 publicações foram elegíveis para análise conforme os critérios de inclusão e exclusão. Parâmetros laboratoriais como a redução de linfócitos e elevação de D-dímeros, lactato desidrogenase e proteína C reativa parecem estar ligados à infecção pelo SARS-CoV-2 e podem servir como indicadores prognósticos da doença. A linfocitopenia e o aumento de D-dímeros são marcadores relacionados ao agravamento da doença e a desfechos desfavoráveis como óbito.


The objective of this study was to identify and gather the main findings available at the beginning of the pandemic, regarding laboratory alterations of hospitalized patients with COVID-19 and to discuss the predominance of these alterations in the severity of the course of the disease. This is a systematic literature review, restricted to publications until April 2020, using the Lilacs and Pubmed databases. A total of 381 publications were found in the consulted databases and of these, 17 publications were eligible for analysis according to the inclusion and exclusion criteria. Laboratory parameters such as the reduction of lymphocytes and the elevation of D-dimers, lactate dehydrogenase and C-reactive protein appear to be linked to SARS-CoV-2 infection and may serve as prognostic indicators of the disease. Lymphocytopenia and increased D-dimers are markers related to disease worsening and unfavorable outcomes such as death.


Subject(s)
Clinical Laboratory Techniques , Systematic Reviews as Topic , COVID-19 , Reference Standards , Biomarkers
15.
Pensar Prát. (Online) ; 25Fev. 2022. Tab, Ilus
Article in Portuguese | LILACS | ID: biblio-1399113

ABSTRACT

Este estudo objetiva identificar e analisar as proprieda-des psicométricas mais utilizadas em artigos, inseridos nas bases de dados Scopus e Web of Science (WOS) entre os anos de 2016 e 2021, que validaram instrumentos sobre a relação torcedor-time de futebol. Optou-se pelo desenho de pesquisas do tipo Revisão Sistemática, complementado pelo uso do software Bliblioshiny for Bibliometrix. Foram coletados 18 artigos e constatou-se que a validade de conteúdo e a confiabilidade por meio do teste de Alfa de Cronbach foram as propriedades mais utilizadas. A primeira tratou da construção de cada elemento do instrumento e a segunda foi um dos principais parâmetros utilizados na avaliação da confiabilidade de instrumentos do tipo questionário (AU).


This study aims to identify and analyze the most used psychometric properties in articles that validated instruments regarding the supporter/football team relationship found in the Scopus and Web of Science data bases between 2016-2021. To achieve this aim, the research was developed as a Systematic Review complemented by using the Bliblioshiny for Bibliometrix software. Eighteen articles were collected, and our results showed that content validity and the Cronbach's alpha test of reliability were the most used properties. While the former addressed the construction of each element of the instrument, the second was one of the main parameters used to evaluate the reliability of instruments such as questionnaires (AU).


El estudio objetivo identificar y analisar las propiedades psicométricas más utilizadas en los artículos que validaron instrumentos sobre la relación hincha-equipo de fútbol, que se encuentran en las bases de datos Scopus y Web of Science entre los años del 2016-2021. Se optó por el diseño de investigaciones del tipo Repaso Sistemático, complementado por el uso del software Bliblioshiny for Bibliometrix. Han sido recoletados 18 artículos y se constató que la validad de contenido y la confiabilidad por medio del teste de Alfa de Cronbach, han sido las propiedades más utilizadas. La primeira trató de la construcción de cada elemento del instrumento y la segunda fue uno de los principales parámetros utilizados en la evaluación de la confiabilidad de instrumentos del tipo cuestionario (AU).


Subject(s)
Humans , Psychometrics , Soccer , Reference Standards , Research , Software , Football
16.
Article in Chinese | WPRIM | ID: wpr-939767

ABSTRACT

OBJECTIVE@#This paper puts forward suggestions on the development of in vitro diagnostic reagents and supervision measures for the post-marketing products, so as to further improve the quality of in vitro diagnostic reagents and ensure the safety use of medical device.@*METHODS@#This paper summarizes the quality of in vitro diagnostic reagents and analyzes the causes of the problems, according to the results of the national medical device supervision and inspection in 2020.@*RESULTS@#The overall quality of in vitro diagnostic reagents for national medical device supervision and inspection in 2020 is stable and the unqualified detection rate is 1.6%. However, there are some problems. For example, the management of raw materials is unscientific, the faultiness in the preparation of reference materials, the understanding of standards is unthorough, and the management of instructions is unimportance.@*CONCLUSIONS@#It is suggested that manufacturers of in vitro diagnostic reagents should improve the binding force of the quality management system, strengthen the awareness of risk management, attach importance to communicate with regulatory authorities, study standards sufficiently and strengthen the management of instructions. It is also suggested that the regulatory authorities should strengthen supervision and inspection, and further complete the evaluation guidance and standard publicity and implementation.


Subject(s)
Indicators and Reagents , Marketing , Reference Standards
17.
Article in Chinese | WPRIM | ID: wpr-936081

ABSTRACT

Tumor spreading through the lymphatic drainage is an important metastatic pathway for rectum and sigmoid colon carcinoma. Regional lymph node dissection, as an important part of radical resection of colorectal cancer, is the main way for patients with colorectal cancer to achieve radical resection and acquire tumor-free survival. The regional lymph nodes of sigmoid cancer include paracolic lymph nodes, intermediate lymph nodes, and central lymph nodes locating at the root of blood vessel, and radical surgery should include lymph node dissection at the above three stations. The lymphatic pathways of metastasis for rectal cancer include longitudinal metastasis within the mesorectum and lateral metastasis beyond the mesorectum. The standard surgical method of rectal cancer is total mesorectal excision (TME) at present, and the resection range includes the metastatic lymph nodes within the mesorectum through the longitudinal pathway. However, there are many different opinions about lateral lymph node dissection(LLND) aiming at the metastatic lymph nodes locating at the lateral space of rectum. The range of lymph node dissection for rectum and sigmoid cancer is a vital factor that determines the prognosis of patients. Insufficient range of dissection can lead to residual metastatic lymph nodes and have serious impacts on the prognosis of patients. Excessive range of dissection can result in greater surgical trauma, prolonged operation time, more blood loss, and higher rate of complication without oncological benefits. Individualizating the appropriate resection range of rectum and sigmoid colon cancer on the basis of standardization and according to the clinical stage and invasion range of tumor demonstrates great significance of ensuring the radical operation, reducing trauma, promoting rehabilitation, protecting the function and improving the prognosis.


Subject(s)
Humans , Lymph Node Excision/methods , Lymph Nodes/pathology , Rectal Neoplasms/pathology , Rectum/pathology , Reference Standards , Sigmoid Neoplasms/surgery
18.
Article in Chinese | WPRIM | ID: wpr-928844

ABSTRACT

Chinese Society of Colorectal Surgery firstly issued guidelines on the chronic constipation in 2008, which played a positive role in the standardization of chronic constipation surgery in China. In recent years, some progress has been made in the basic and clinical researches on chronic constipation. But in terms of clinical practice, there is still a lack of gold standard and high-level clinical research evidence, and surgeons have no authoritative reference in preoperative evaluation, operation selection and efficacy evaluation. In order to further standardize the diagnostic assessment and surgical treatment of chronic constipation, it is necessary to update the guidelines. Based on the published literatures combined with the clinical experience of experts, the "Clinical practice guideline on the evaluation and management of chronic constipation for Chinese adults (2022 edition)" has been formulated, which aims at the common problems in constipation assessment and treatment, is problem-oriented, and puts forward rationalization suggestions on the basis of evidence. It is expected to contribute to the learning and practice on constipation for Chinese surgeons and other relevant medical practitioners, and improve the overall diagnosis and treatment level of constipation surgery in China.


Subject(s)
Adult , Asians , China , Constipation/therapy , Humans , Reference Standards
19.
Article in Chinese | WPRIM | ID: wpr-928167

ABSTRACT

Through literature research and standard retrieval, Corydalis-derived medicinal materials, the origins, and related standards were summarized. Finally, 27 medicinal materials were screened out, involving 71 species(varieties). Among them, only 11 are recorded in Chinese Pharmacopoeia(2020), National Standard for Chinese Patent Drugs·Tibetan Medicine, Tibetan Medicine Standards, and other local standards, including Corydalis Bungeanae Herba and Corydalis Herba. The names and original plants of the medicinal materials are different in different standards, and the phenomena of "same medicinal material with different names" and "same name for different medicinal materials" are prominent. Most standards only include the traits, microscopic identification, and physico-chemical property identification, with unsound quality criteria. Thus, efforts should be made to strengthen the sorting of Corydalis medicinal plants, herbal textual research, and investigation of the resources and utilization. Moreover, via modern techniques, the chemical components and medicinal material basis of different original plants should be explored and sound quality standards should be established to improve the safety and quality of Corydalis-derived medicinal materials. Summarizing Corydalis medicinal plants, Corydalis-derived medicinal materials, and related standards, this study is expected to provide a reference for the standard formulation, quality evaluation, expansion of drug sources, and rational development and utilization of Corydalis resources.


Subject(s)
Corydalis , Drugs, Chinese Herbal/chemistry , Medicine, Chinese Traditional , Medicine, Tibetan Traditional , Plants, Medicinal/chemistry , Reference Standards
20.
Article in Chinese | WPRIM | ID: wpr-928040

ABSTRACT

Against the backdrop of "Internet+" and Made in China 2025, Chinese medicinal processing equipment embraces various opportunities and develops to an unprecedented level. In the 20 years of the new century, the processing equipment has gradually developed in the direction of high efficiency, energy saving, environmental protection, integration, and automation, and this field has tended to highlight the establishment and application of the linkage production line for the processing of Chinese medicinal decoction pieces. Integrating automation control technology, online detection technique, and the internet of things technology, the online detection system of Chinese medicinal processing equipment and the computer information management system of Chinese medicinal proces-sing are the mainstream development trends of Chinese medicinal processing equipment. Standard Chinese medicine processing equipment is the prerequisite for the standardization of processing parameters. A standard system for processing equipment and processing parameters is the key to the modernization of Chinese medicinal decoction pieces. This paper summarized the research and application of Chinese medicinal processing equipment in the 20 years of the 21 st century and predicted the development trend, which is expected to serve as a reference for the technological innovation and development of the processing equipment.


Subject(s)
Automation , Drugs, Chinese Herbal , Medicine, Chinese Traditional , Quality Control , Reference Standards
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