Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 420
Filter
1.
Lima; Perú. Ministerio de Salud; 1 ed; Mar. 2022. 54 p. ilus.
Monography in Spanish | MINSAPERU, LILACS, LIPECS, MINSAPERU | ID: biblio-1362742

ABSTRACT

En el presente rotafolio encontrará conceptos básicos sobre la salud respiratoria y la tuberculosis, sus síntomas, su forma de contagio y las medidas preventivas a realizar en la familia y el domicilio


Subject(s)
Respiration Disorders , Tuberculosis , Tuberculosis, Multidrug-Resistant , Disease Prevention
2.
Lima; Perú. Ministerio de Salud. Dirección General de Intervenciones Estratégicas en Salud Pública. Dirección de Prevención y Control de Tuberculosis. Dirección de Promoción de la Salud; 1 ed; Feb. 2022. 44 p. ilus.
Monography in Spanish | MINSAPERU, LILACS, LIPECS, MINSAPERU | ID: biblio-1357751

ABSTRACT

La cartilla, a través de fichas pedagógicas, te brinda información sobre los conceptos básicos de la salud respiratoria y todo lo que necesitas saber como agente comunitario para que realices la promoción de la salud a las personas afectadas con tuberculosis, a sus familias y la comunidad de su entorno inmediato


Subject(s)
Patient Escort Service , Respiration Disorders , Respiratory Tract Infections , Tuberculosis , Tuberculosis, Multidrug-Resistant , Community Health Workers , Patient-Centered Care , Disease Prevention , Health Promotion
3.
Lima; Perú. Ministerio de Salud. Dirección General de Intervenciones Estratégicas en Salud Pública. Dirección de Prevención y Control de Tuberculosis. Dirección de Promoción de la Salud; 1 ed; Feb. 2022. 128 p. ilus.
Monography in Spanish | MINSAPERU, LILACS, LIPECS, MINSAPERU | ID: biblio-1357755

ABSTRACT

La publicación, cuyos contenidos se agrupan en cinco sesiones: sesión 1, "Prácticas y entornos para mantener la salud respiratoria"; sesión 2, "Conociendo la tuberculosis"; sesión 3, "Prevenimos la tuberculosis"; sesión 4, "Importancia de la adherencia al tratamiento de la tuberculosis"; sesión 5 "¡Nos preparamos para nuestras visitas domiciliarias!" en el caso de la modalidad presencial y "¡Nos preparamos para acompañar a la Persona Afectada por Tuberculosis - PAT y su familia!" en la modalidad virtual. Asimismo, se plantea desde el enfoque del aprendizaje de adultos, elaborado para la modalidad presencial y modalidad virtual, a partir de una metodología activa participativa. Las sesiones consideran diversas dinámicas, cuya aplicación es flexible por lo que pueden adaptarse de acuerdo a las características de cada grupo


Subject(s)
Patient Escort Service , Respiration Disorders , Respiratory Tract Infections , Tuberculosis , Health Knowledge, Attitudes, Practice , Health Personnel , Tuberculosis, Multidrug-Resistant , Community Health Workers , Patient-Centered Care , Health Promotion
4.
Pesqui. vet. bras ; 42: e06839, 2022. tab, ilus
Article in English | LILACS, VETINDEX | ID: biblio-1356554

ABSTRACT

This study describes the spontaneous and experimental salinomycin poisoning associated with the use of florfenicol and warns about the effects of the administration of antibiotics to animals that receive ionophores in the feed as growth promoters. A batch with 1,200 finishing pigs fed a diet containing 30ppm of salinomycin received florfenicol (60ppm via feed) to control respiratory diseases. Twenty-seven pigs had difficulty walking, tip-toe walking, muscle tremors, and anorexia seven days after the start of treatment. Twenty-two animals died, 10 recovered, and two were sent to the Laboratory of Animal Pathology of CAV-UDESC to be necropsied. The experimental reproduction of the disease was carried out to clarify the possible influence of florfenicol on salinomycin poisoning using 12 pigs divided into four groups with three animals each, treated for 16 days with diets containing no additives (Group 1), 50ppm of salinomycin (Group 2), 40ppm of florfenicol (Group 3), and 50ppm of salinomycin and 40ppm of florfenicol (Group 4). Only animals in Group 4 became ill. The clinical disease was reproduced from the ingestion of 24.67mg/kg/LW of salinomycin and 19.74mg/kg/LW of florfenicol. Both natural and experimental salinomycin poisoning associated with the use of florfenicol caused a condition of myopathy characterized in histology by hyaline degeneration and floccular necrosis of skeletal fibers, with macrophage infiltrate, associated with the figures of regeneration in skeletal muscles and multifocal areas of the proliferation of fibroblasts, being more intense in the longissimus dorsi and semimembranosus muscles. Therefore, florfenicol can cause the accumulation of ionophore salinomycin in the animal organism, resulting in a condition of toxic myopathy.(AU)


O presente trabalho descreve as intoxicações espontânea e experimental por salinomicina associada ao uso de florfenicol e alerta sobre os efeitos da administração de antibióticos aos animais que recebem ionóforos na ração como promotores de crescimento. Um lote com 1.200 suínos em fase de terminação, alimentados com ração contendo 30ppm de salinomicina, recebeu florfenicol (60ppm via ração) para o controle de doenças respiratórias. Sete dias após o início do tratamento, 27 suínos apresentaram dificuldade de locomoção, "caminhar em brasa", tremores musculares e anorexia. Vinte e dois animais morreram, 10 recuperaram-se e dois foram encaminhados ao Laboratório de Patologia Animal (CAV-UDESC) para serem necropsiados. Para esclarecer a possível influência do florfenicol na toxicidade da salinomicina foi realizada a reprodução experimental da doença utilizando 12 suínos, divididos em 4 grupos com 3 animais cada, tratados por 16 dias com rações contendo: Grupo 1 = sem aditivos, Grupo 2 = 50ppm de salinomicina, Grupo 3 = 40ppm de florfenicol e Grupo 4 = 50ppm de salinomicina e 40ppm de florfenicol. Somente os animais do Grupo 4 adoeceram. A doença clínica foi reproduzida a partir da ingestão de 24,67mg/kg/PV de salinomicina e 19,74 mg/kg/PV de florfenicol. Tanto a intoxicação natural quanto a experimental por salinomicina associada ao uso de florfenicol provocaram um quadro de miopatia caracterizado na histologia por degeneração hialina e necrose flocular das fibras esqueléticas, com infiltrado macrofágico, associada às figuras de regeneração na musculatura esquelética e áreas multifocais de proliferação de fibroblastos, sendo mais intensas nos músculos longissimus dorsi e semimembranoso. Conclui-se que, o florfenicol tem a capacidade de ocasionar o acúmulo do ionóforo salinomicina no organismo animal, resultando em um quadro de miopatia tóxica.(AU)


Subject(s)
Animals , Poisoning/veterinary , Sus scrofa , Myotoxicity/etiology , Ionophores/toxicity , Anti-Bacterial Agents/toxicity , Respiration Disorders/veterinary , Diet/veterinary , Animal Feed
5.
Arch. pediatr. Urug ; 92(2): e214, dic. 2021. tab
Article in Spanish | LILACS, BNUY, UY-BNMED | ID: biblio-1339134

ABSTRACT

Las enfermedades neuromusculares (ENM) afectan los distintos componentes de la unidad motora. Desde el diagnóstico deben ser seguidos por un equipo interdisciplinario, donde el neumólogo pediátrico desempeña un papel importante en la valoración de la pérdida de fuerza muscular cuando afecta a la musculatura respiratoria o de la vía aérea superior. Objetivos: conocer las diferentes enfermedades neuromusculares atendidas en el Centro Hospitalario Pereira Rossell, analizar las características de la población y describir los resultados de los principales estudios solicitados por la policlínica de neumológica pediátrica. Metodología: estudio descriptivo, analítico y retrospectivo de los pacientes con enfermedad neuromuscular atendidos en el Centro Hospitalario Pereira Rossell entre el 1/6/2006 y el 31/12/2019. Resultados: las patologías neuromusculares más frecuentemente encontradas fueron distrofias musculares, miopatías, distrofia miotónica de Steinert y atrofia muscular espinal. No tienen diagnóstico definitivo 21/73 pacientes. La espirometría mostró una alteración restrictiva en la mayoría de los pacientes. Para descartar trastornos respiratorios del sueño se realizó oximetría nocturna con gasometría al despertar. La hipoventilación nocturna y las apneas obstructivas fueron las alteraciones encontradas. En 12/73 se inició ventilación no invasiva. Conclusiones: los pacientes con ENM experimentan un deterioro progresivo de la función respiratoria que contribuye a una elevada tasa de morbimortalidad. La evaluación y seguimiento regular de la función respiratoria junto con estudios de sueño, son fundamentales para el inicio oportuno de ventilación no invasiva.


Neuromuscular diseases (NMD) affect the different components of the motor system. As of diagnosis, they should be followed by an interdisciplinary team, in which pediatric pulmonologists play an important role in assessing the loss of muscle strength when NMD affects the respiratory or upper airway muscles. Objectives: to learn about the different neuromuscular diseases treated at the Pereira Rossell Hospital Center, to analyze the characteristics of this population and to describe the results of the main studies requested by the pediatric pulmonology clinic. Methodology: descriptive, analytical and retrospective study of patients with neuromuscular disease treated at the Pereira Rossell Hospital Center between 6/1/2006 and 12/31/2019. Results: the most frequent neuromuscular pathologies were muscular dystrophies, myopathies, Steinert's myotonic dystrophy and spinal muscular atrophy. 21/73 patients did not have a definitive diagnosis. Spirometry showed a restrictive alteration in most of the patients. To rule out respiratory sleep disorders, nocturnal oximetry with blood gas was performed upon awakening, with nocturnal hypoventilation and obstructive apneas being the alterations found. In 12/73 non-invasive ventilation was applied. Conclusions: patients with NMD experience a progressive deterioration of respiratory function that contributes to a high rate of morbidity and mortality. Regular evaluation and monitoring of respiratory function, along with sleep studies, are essential for the timely initiation of non-invasive ventilation.


As doenças neuromusculares (DNM) afetam os diferentes componentes da unidade motora. Desde o diagnóstico, os pacientes devem ser acompanhados por uma equipe interdisciplinar, onde o pneumologista pediátrico desempenha um papel importante na avaliação da perda de força muscular quando atinge a musculatura respiratória ou das vias aéreas superiores. Objetivos: conhecer as diferentes doenças neuromusculares tratadas no Centro Hospitalar Pereira Rossell, analisar as características desta população e descrever os resultados dos principais estudos solicitados à policlínica de pneumologia pediátrica. Metodologia: estudo descritivo, analítico e retrospectivo de pacientes com doenças neuromusculares atendidos no Centro Hospitalar Pereira Rossell entre 01/06/2006 e 31/12/2019. Resultados: as patologias neuromusculares mais encontradas foram distrofias musculares, miopatias, distrofia miotônica de Steinert e atrofia muscular espinhal. 21/73 pacientes não tiveram um diagnóstico definitivo. A espirometria mostrou alteração restritiva na maioria dos pacientes. Para afastar distúrbios respiratórios do sono, foi realizada oximetria noturna com gasometria ao despertar, sendo a hipoventilação noturna e as apneias obstrutivas as alterações encontradas. Em 12/73 foi iniciada ventilação não invasiva. Conclusões: os pacientes com DNM experimentam uma deterioração progressiva da função respiratória que contribui para uma alta taxa de morbidade e mortalidade. A avaliação regular e o monitoramento da função respiratória, juntamente com os estudos do sono, são essenciais para o início oportuno da ventilação não invasiva.


Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Neuromuscular Diseases/classification , Neuromuscular Diseases/epidemiology , Respiration Disorders/etiology , Respiration Disorders/therapy , Uruguay/epidemiology , Cross-Sectional Studies , Retrospective Studies , Noninvasive Ventilation , Neuromuscular Diseases/complications , Neuromuscular Diseases/diagnosis
6.
Arch. argent. pediatr ; 119(4): 245-250, agosto 2021. tab, ilus
Article in English, Spanish | LILACS, BINACIS | ID: biblio-1280906

ABSTRACT

Introducción: El aumento de prevalencia de trastornos respiratorios del sueño (TRS) y su relación con obesidad e hipertensión arterial (HTA) ha sido poco explorado en adolescentes. El objetivo de este estudio fue investigar la prevalencia de TRS y ronquido en esta población y analizar su asociación con obesidad e HTA. Población y métodos: Se realizó un estudio descriptivo de corte transversal en una muestra de adolescentes. Se realizaron mediciones de peso, talla, perímetro de cintura y cuello, tensión arterial, y el Cuestionario de Sueño Pediátrico (PSQ, por su sigla en inglés). Resultados: Participaron 826 adolescentes, 58 (7 %) presentaron TRS (varones: 5,8 %; mujeres: 8 %) y 80 (9,7 %) se consideraron roncadores (varones: 10,4 %; mujeres: 9,1 %). Se detectaron sobrepeso y obesidad en 216 (26,2 %) y 149 (18 %) sujetos, respectivamente. Una mayor proporción de sujetos con obesidad presentaron TRS con respecto a quienes no tenían obesidad (12,8 % versus 5,8 %; p = 0,004). La misma asociación fue encontrada para el ronquido (18,2 % versus 7,8 %; <0,001). El 24,6 % dormía menos de 8 horas por día. El 12,6 % presentó valores compatibles con HTA, con una asociación significativa con obesidad y horas de sueño. Conclusión: Se observó una prevalencia elevada de TRS y ronquido en adolescentes y una asociación entre obesidad e HTA, que pone de manifiesto la importancia de abordar esta problemática de manera temprana a fin de evitar complicaciones


ntroduction: The increased prevalence of sleep-disordered breathing (SDB) and its association with obesity and hypertension (HTN) have not been thoroughly explored in adolescents. The objective of this study was to investigate the prevalence of SDB and snoring in this population and analyze its association with obesity and HTN. Population and methods: This was a descriptive, cross-sectional study in a sample of adolescents. Weight, height, waist and neck circumference, and blood pressure were measured, and the Pediatric Sleep Questionnaire (PSQ) was administered. Results: A total of 826 adolescents participated, 58 (7 %) had SDB (males: 5.8 %; females: 8 %), and 80 (9.7 %) were considered snorers (males: 10.4 %; females: 9.1 %). Overweight and obesity were detected in 216 (26.2 %) and 149 (18 %) participants, respectively. A higher proportion of subjects with obesity had SDB compared to those who were not obese (12.8 % versus 5.8 %; p = 0.004). The same association was observed with snoring (18.2 % versus 7.8 %; p < 0.001). Also, 24.6 % slept less than 8 hours a day and 12.6 % had values compatible with HTN, with a significant association with obesity and sleep hours. Conclusion: A high prevalence of SDB and snoring was observed in adolescents, together with an association with obesity and HTN, which highlights the relevance of addressing this problem in an early manner in order to prevent complications


Subject(s)
Humans , Male , Female , Adolescent , Sleep Apnea Syndromes , Sleep Wake Disorders , Respiration Disorders , Snoring , Epidemiology, Descriptive , Prevalence , Cross-Sectional Studies , Surveys and Questionnaires , Overweight , Hypertension
7.
Arch. argent. pediatr ; 119(3): S67-S76, Junio 2021. tab
Article in Spanish | LILACS, BINACIS | ID: biblio-1248259

ABSTRACT

El síndrome de apneas e hipoapneas obstructivas del sueño se asocia con una disminución de la calidad de vida, bajo rendimiento escolar y, hasta en el 40% de los niños, trastornos de conducta como hiperactividad, enuresis, ansiedad y depresión. Varios estudios demostraron que la adenoamigdalectomía es efectiva para mejorar o resolver los trastornos respiratorios del sueño. Si bien esta cirugía tiene resultados beneficiosos, no está exenta de riesgos. El dolor y el sangrado posoperatorio son las dos causas principales de morbilidad. Otras complicaciones de la cirugía son las náuseas y los vómitos posoperatorios, el retraso en la alimentación, la deshidratación, la otalgia referida, los cambios en la voz y, raras veces, la muerte.En este artículo se realizan recomendaciones sobre el cuidado posoperatorio de los niños con adenoamigdalectomía


Obstructive sleep apnea and hypopnea syndrome is associated with decreased quality of life, poor school performance and, in up to 40% of children, behavioral problems such as hyperactivity, enuresis, anxiety and depression. Several studies have shown that adenoamygdalectomy is effective in improving or resolving sleep-disordered breathing. While this surgery has beneficial results, it is not without risks. Postoperative pain and bleeding are the two main causes of morbidity. Other complications of surgery include postoperative nausea and vomiting, delayed feeding, dehydration, referred earache, voice changes, and, rarely, death. Recommendations on postoperative care for children undergoing adenoamygdalectomy are mentioned in this article.


Subject(s)
Humans , Male , Female , Child , Tonsillectomy , Adenoidectomy , Postoperative Complications , Respiration Disorders , Adenoids/surgery , Sleep Apnea, Obstructive
9.
Article in English | WPRIM | ID: wpr-888608

ABSTRACT

BACKGROUND@#Ambient fine particle (PM@*METHODS@#A time-stratified case-crossover design was used to analyze YLL from respiratory diseases in the elderly related to ambient PM@*RESULTS@#Each 10 μg/m@*CONCLUSIONS@#Birth season which reflects the early-life PM


Subject(s)
Aged , Aged, 80 and over , Air Pollutants/analysis , Cause of Death , China/epidemiology , Cross-Over Studies , Environmental Exposure/analysis , Humans , Life Expectancy , Particulate Matter/analysis , Respiration Disorders/mortality , Seasons
10.
Article in English | WPRIM | ID: wpr-922191

ABSTRACT

BACKGROUND@#International Labour Organization (ILO) report indicates more than 2.4 million workers die from work-related diseases and accidents each year. Work-related respiratory ailments related to airborne particulate matter such as flour dust are responsible for about 386,000 deaths and 6.6 million illness-adjusted life years. Even though exposure to flour dust together with the extreme expansions of flour mill sectors is a priority health concern, extent of the problem is little investigated in Ethiopia. The aim of this study was to evaluate the magnitude and risk factors of work-related respiratory symptoms among flour mill workers in Bahir Dar City, Ethiopia.@*METHODS@#This study employed a comparative cross-sectional survey of 560 samples (280 exposed group from flour mill workers and 280 unexposed group from office workers) with a stratified random sampling technique. The study was conducted from March to April 2019 in Bahir Dar City, Northwest Ethiopia. We used the British Medical Research Council (BMRC) questionnaire to assess work-related respiratory symptoms. The questionnaire was pretested and interview administered to collect data. Binary logistic regression analysis was fitted to evaluate significant factors of respiratory symptoms at a < 0.05 p value. Adjusted odds ratio (AOR) with a confidence interval (CI) of 95% was calculated to determine a strength of association.@*RESULTS@#All the sampled participants had fully responded to the interview. The median age of exposed and unexposed groups was 28.5 interquartile range (IQR, 20) and 31 (IQR, 15) years, respectively. The prevalence of work-related respiratory symptoms among flour mill workers was substantially higher than that of among controls, 63.9% and 20.7%, respectively (Χ@*CONCLUSION@#Respiratory symptoms emanating from exposure to various flour dusts were significantly higher among flour mill workers than among the control group. Therefore, we recommend the need to effectively implement health and safety programs that account for the reduction of dust at a source, use of engineering controls (e.g., provision of adequate ventilation systems), use of administrative measures (e.g., training program and health surveillance) and provision of a suitable personal protective equipment (PPE). Furthermore, it is vital to integrate workplace health and safety programs to the wider public health policies and strategies to effectively mitigate the burden of work-related respiratory conditions. We also encourage future studies to evaluate concentration of flour dusts combined with physical examinations to establish plausible associations of respiratory symptoms with dusts of flour mill-related origin.


Subject(s)
Adult , Air Pollutants, Occupational/adverse effects , Cross-Sectional Studies , Dust , Ethiopia/epidemiology , Female , Flour , Humans , Male , Occupational Diseases/epidemiology , Particulate Matter/adverse effects , Prevalence , Respiration Disorders/epidemiology , Risk Factors , Surveys and Questionnaires , Workplace , Young Adult
11.
Acta Physiologica Sinica ; (6): 1043-1053, 2021.
Article in Chinese | WPRIM | ID: wpr-921309

ABSTRACT

Lower respiratory tract infection (LRTI) induced by respiratory syncytial virus (RSV) is an important cause of hospitalization for infants. Compared with adults, infants are more likely to cause serious respiratory diseases after RSV infection due to the specific immature airway structure and immune system. The balance of immune resistance and immune tolerance of the host is critical to effective virus clearance and disease control. This paper reviews the relationship between RSV infection and respiratory diseases in infancy, the influence factors of the high pathogenicity of RSV infection in early life, as well as the research progress of anti-RSV therapy, and expands the specific molecular events regulating immune resistance and immune tolerance. We expect to present new ideas for the prevention and treatment of RSV-related respiratory diseases in clinical practice.


Subject(s)
Humans , Infant , Respiration Disorders , Respiratory Syncytial Virus Infections , Respiratory Syncytial Viruses , Respiratory Tract Infections
14.
Rev. chil. neuro-psiquiatr ; 58(3): 259-269, set. 2020. tab, ilus
Article in Spanish | LILACS | ID: biblio-1138580

ABSTRACT

Resumen Los pacientes con Esclerosis múltiples tienen mayor tasa de trastornos del sueño que la población general. Los trastornos del sueño más prevalentes son: somnolencia diurna, insomnio, síndrome de piernas inquietas, trastornos respiratorios del sueño y narcolepsia. Los principales factores involucrados en la calidad del sueño en estos pacientes son la nicturia, dolor inespecífico, depresión, efectos colaterales de las terapias, ubicación de las lesiones y severidad de la enfermedad. La presencia de estos trastornos contribuyen de forma significativa a la reducción en la calidad de vida y funcionalidad diurna. A pesar de su alta frecuencia, está demostrado que los trastornos del sueño en estos pacientes son subdiagnosticados. Esta revisión, busca hacer un repaso de los trastornos del sueño más frecuentes en pacientes con esclerosis múltiple, su fisiopatología y clínica.


Sleep disorders occur in multiple sclerosis patients at higher frequency than the general population. Among sleep disorders; daytime sleepiness, insomnia, restless legs syndrome, sleep disordered breathing and narcolepsy have all been reported to be more frequent in multiple sclerosis patients. Factors that influence the quality of sleep in this population include pain, nycturia, depression, medication effects, location of lesions, and disease severity. Sleep disorders have the potential to negatively impact overall health and quality of life in these patients. Sleep disorders in multiple sclerosis patients are known to be clinically underdiagnosed. High suspicion of this condition is pivotal to prompt diagnosis and treatment. The aim of this paper is to review pathophysiology and clinical aspect of the most frequent sleep disorders in multiples sclerosis patients.


Subject(s)
Humans , Quality of Life , Sleep Wake Disorders , Multiple Sclerosis , Respiration Disorders , Restless Legs Syndrome , Sleep Apnea Syndromes
15.
Medisan ; 24(3)mayo.-jun. 2020. tab
Article in Spanish | LILACS, CUMED | ID: biblio-1125116

ABSTRACT

Introducción: La papilomatosis respiratoria recurrente es una enfermedad infrecuente de la vía aérea que afecta a niños y adultos, causada por el papilomavirus. Objetivo: Caracterizar niños con papilomatosis respiratoria recurrente desde los puntos de vista clínico, epidemiológico y terapéutico, así como evaluar su evolución a corto y mediano plazos. Métodos: Se realizó una investigación observacional, longitudinal y prospectiva de 40 niños con papilomatosis respiratoria recurrente, atendidos en el Servicio de Otorrinolaringología del Hospital Infantil Docente Sur Dr. Antonio María Béguez César de Santiago de Cuba, desde enero del 2010 hasta diciembre del 2016. Resultados: Los pacientes incluidos en el estudio representaron 3,2 % del total de los ingresos. Predominó el sexo masculino (60,0 %); el promedio de edad fue de 8,6 ± 4 años. Existió asociación estadística entre la localización anatómica de las lesiones y el sexo masculino; sin embargo, no hubo dicha asociación con la edad. Las localizaciones orofaríngea (50,0 %) y laríngea (42,5 %) fueron las de mayor observancia. El parto transvaginal se asoció con el mayor número de pacientes que presentaron la citada afección (85,0 %) y el tratamiento con exéresis e interferón se asoció a la evolución satisfactoria en 95,8 % de los afectados. Conclusiones: Las características clínicas y epidemiologias de los pacientes con papilomatosis respiratoria recurrente de esta casuística no difieren del contexto epidemiológico mundial, siendo una entidad de observación poco frecuente, pero no rara en los servicios de pediatría.


Introduction n The recurrent respiratory papillomatosis is an uncommon disease of the airways that affects children and adults, caused by the papillomavirus. Objective: To characterize children with recurrent respiratory papillomatosis from the clinical, epidemiologic and therapeutic points of view, as well as to evaluate their clinical course at short and mid terms. Methods: An observational, longitudinal and prospective investigation of 40 children with recurrent respiratory papillomatosis was carried out, they were assisted in the Otolaryngology Service of Dr. Antonio María Béguez Cesar Teaching Southern Children Hospital in Santiago de Cuba, from January, 2010 to December, 2016. Results: The patients included in the study represented 3.2 % of the total of admissions. The male sex prevailed (60.0 %); the average age was 8.6 ± 4 years. Statistical association existed between the anatomical localization of the lesions and the male sex; however, there was no such association with the age. The oropharyngeal (50.0 %) and laryngeal (42.5 %) localizations were those of more observance. The transvaginal childbirth was associated with the higher number of patients that presented the mentioned disorder (85.0 %) and the treatment with exeresis and Interferon was associated with the satisfactory clinical course in 95.8 % of those affected. Conclusions: The clinical and epidemiological characteristics of patients with recurrent respiratory papillomatosis of this case material don't differ from the world epidemiological context, being an unusual observation entity, but not strange in the pediatrics services.


Subject(s)
Papilloma , Respiration Disorders , Child , Respiratory Tract Infections/epidemiology
17.
Acta Physiologica Sinica ; (6): 575-585, 2020.
Article in Chinese | WPRIM | ID: wpr-878203

ABSTRACT

Ferroptosis is a novel form of regulated cell death which is dependent on iron and reactive oxygen species (ROS) and associated with the accumulation of lipid peroxides. It is obviously different from other cell death types in terms of morphology, biochemistry, genetics, etc. Also, it is related to the production of iron catalyzed lipid peroxides which is triggered by non-enzymatic or enzymatic reactions. Ferroptosis has been proved to be involved in hematological diseases, cardio-cerebrovascular diseases, liver and kidney diseases. This paper will review the definition, mechanism, inducers of ferroptosis, as well as the function of ferroptosis in respiratory system. We expect to present a new concept for respiratory research and suggest potential targets for clinical prevention and treatment of respiratory diseases.


Subject(s)
Cell Death , Ferroptosis , Humans , Iron , Reactive Oxygen Species , Respiration Disorders
18.
Article in English | AIM, AIM | ID: biblio-1258602

ABSTRACT

Introduction: Globally respiratory diseases, comprising a broad range of disease conditions due to infectious and non-infectious causes, are a major cause of childhood morbidity and mortality. Thus, identification of the burden of respiratory illness will ensure appropriate interventions towards reducing its attendant morbidity and mortality. The study was conducted to identify the burden, spectrum and outcome of respiratory diseases in hospitalized children at University of Ilorin Teaching Hospital, North-Central Nigeria. Methods: A retrospective descriptive cross-sectional study involving children admitted through the emergency paediatric unit over five years (January 2013-December 2017) was conducted. Data on demography, diagnosis, comorbidities and complications, duration of admission, and outcome were collected and analyzed using SPSS 20. Results: Of the total 7012 children admitted, 1939(27.7%) were due to respiratory diseases with a median age of 16 (interquartile range {IQR} 7-36) months. Males were 994(51.3%) and 945(48.7%) females. Infectious diseases were the most common cause of admission. Pneumonia (50.1%) and aspiration pneumonitis (5.1%) accounted for the highest admissions due to infective and non-infective respiratory diseases respectively. Overall, respiratory diseases accounted for 20.7% (119/574) of the overall mortality among all admissions while the all respiratory disease mortality was 6.1% (119/1939). The major contributors to mortality were pneumonia, aspiration pneumonitis and tuberculosis accounting for 81(68.1%), 12(10.1%) and nine (7.6%) deaths respectively. The median duration of hospital stay was four days [IQR: 2 to 6 days]. A significantly higher proportion of the deaths occurred with four days of admission and 82.4% of the deaths occurred among those aged less than five years. A higher number of females (70, 58.8%) died compared to males (49, 41.2%), p=0.05. Conclusion: Pneumonia and aspiration pneumonitis are major contributors to morbidity and mortality due to respiratory diseases for which interventions towards improving childhood health indices should be prioritized


Subject(s)
Child , Hospitals, Teaching , Nigeria , Pediatrics , Pneumonia , Respiration Disorders
20.
Article in Spanish | LILACS, COLNAL | ID: biblio-1292508

ABSTRACT

ARTÍCULO DE INVESTIGACIÓNREVISTA DE INVESTIGACIÓN EN SALUD. UNIVERSIDAD DE BOYACÁ2020;7 (2):118-136. doi: https://doi.org/Rehabilitación Pulmonar en Pacientes con Enfermedad Pulmonar Obstructiva Crónica Flor Á Umbacía-Salas1 , Laura J Silva-Rodríguez2 , Clara L Palencia-Mojica1 , Alba Y Polanía-Robayo1RESUMENIntroducción. La enfermedad Pulmonar Obstructiva Crónica (EPOC) se caracteriza por ser una patología prevenible y tratable, que presenta sintomatología respiratoria permanente por restricción progresiva del flujo aéreo. La rehabilitación pulmonar, ha demostrado mejoría en la actividad física, disminución de la disnea y sintomatología respiratoria, además de mejorar la calidad de vida. El objetivo de este artículo es analizar la evidencia científica disponible sobre la rehabilitación pulmonar en la Enferme-dad Pulmonar Obstructiva. Materiales y métodos. Para la búsqueda bibliográfica se incluyeron artículos de las bases de datos PudMed, Jane, Science Direct, Ovid, Medline, Proquest, publicados en los últimos cinco años con evidencia actualizada en relación a la rehabilitación pulmonar EPOC. Se seleccionaron 53 artículos de interés en la temática cumpliendo con los criterios de inclusión. Resultados. Los artículos seleccionados abordan temática de rehabilitación Pulmonar en EPOC, con aplicación de protocolos que incluyen cuestionarios de evaluación respiratoria. Dentro de los resultados analizados, no se evidencia diferencia demográfica significativa entre los grupos intervenidos, la incidencia de participación es de 100 pacientes para cada programa de rehabilita-ción pulmonar, la media de edad es de 59 años, y los programas de rehabilitación se desarrollan a nivel hospitalario, comunitario y ambulatorio. Conclusiones. Implementar programas de rehabilitación pulmonar en pacientes con EPOC, constituye un elemen-to fundamental en el manejo de esta enfermedad, mostrando efectos benéficos al optimizar sintomatología, capacidad en el ejercicio, control sobre la enfermedad y mejoría en la calidad de vida


Introduction. Chronic Obstructive Pulmonary Disease (COPD) is a preventable and treatable condition with permanent respiratory symptoms and progressive restriction of airflow. Pulmonary rehabilitation has shown improvement in physical activity, decrease in dyspnea and respiratory symptoms, in addition to improving quality of life. The aim of this article is to analyze the available scientific evidence on pulmonary rehabilitation in Obstructive Pulmonary Disease. Materials and methods. For the bibliographic search we included articles from the databases PudMed, Jane, Science Direct, Ovid, Medline, Proquest, published in the last five years with updated evidence related to COPD pulmonary rehabilitation. Fifty-three articles of interest in the field were selected and met the inclusion criteria. Results. The selected articles address the topic of pulmonary rehabilitation in COPD, with application of protocols that include respiratory assessment questionnaires. Within the analyzed results, no signifi-cant demographic difference between the intervened groups is evident, the incidence of participation is 100 patients for each pulmonary rehabilitation program, the average age was 59 years, and the rehabilitation programs are developed at hospital, community and outpatient level. Conclusions. Implementing pulmonary rehabilitation programs in patients with COPD is a fundamental element in the management of this disease, showing beneficial effects by optimizing symptoms, exercise capacity, control over the disease and improvement in quality of life.


Introdução: A Doença Pulmonar Obstrutiva Crônica (DPOC) caracteriza-se por ser uma patologia evi-tável e tratável, que apresenta sintomas respiratórios permanentes devido à restrição progressiva do fluxo de ar. A reabilitação pulmonar tem mostrado melhora na atividade física, diminuição da dispneia e dos sintomas respiratórios, além de melhorar a qualidade de vida. O objetivo deste artigo é anali-sar as evidências científicas disponíveis sobre reabilitação pulmonar na doença pulmonar obstrutiva. Ma-teriais e métodos. Para a busca bibliográfica, foram incluídos artigos das bases de dados PudMed, Jane, Science Direct, Ovid, Medline, Proquest, publicados nos últimos cinco anos com evidências atua-lizadas em relação à reabilitação pulmonar de DPOC. Foram selecionados 53 artigos de interesse no assunto, atendendo aos critérios de inclusão. Resultados: Os artigos selecionados abordam a te-mática da reabilitação pulmonar na DPOC, com a aplicação de protocolos que incluem questionários de avaliação respiratória. Dentre os resultados analisados, não há diferença demográfica significativa entre os grupos intervencionados, a incidência de participação é de 100 pacientes para cada programa de reabilitação pulmonar, a média de idade é de 59 anos, e os programas de reabilitação são desenvol-vidos em nível hospitalar, comunitário e ambulatorial. Conclusões: A implementação de programas de reabilitação pulmonar em pacientes com DPOC cons-titui elemento fundamental no manejo desta doen-ça, apresentando efeitos benéficos pela otimi-zação dos sintomas, capacidade de exercício, controle da doença e melhora da qualidade de vida.


Subject(s)
Rehabilitation , Respiration Disorders , Breathing Exercises , Pulmonary Disease, Chronic Obstructive , Dyspnea
SELECTION OF CITATIONS
SEARCH DETAIL