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1.
Int. j. med. surg. sci. (Print) ; 8(2): 1-17, jun. 2021. tab, ilus, graf
Article in English | LILACS | ID: biblio-1284420

ABSTRACT

Background: Echocardiographic predictors for new onset heart failure in patients with ischemic heart disease with reduced left ventricular ejection fraction (HFrEF) or with preserved left ventricular ejection fraction (HFpEF) in Ethiopian and Sub-Saharan African is not well-known.Methods: Two hundred twenty-eight patients with ischemic heart disease were retrospectively recruited and followed. Analysis on baseline clinical and echocardiographic characteristics of patients, and risk factors for new onset HFpEF and new onset HFrEF were done. The exclusion criteria were known heart failure at baseline and those who did not have echocardiography data.Results: During the follow up period, heart failure developed in 62.2% (61/98) of ischemic heart disease patients with preserved left ventricular ejection fraction and in 70.1% (92/130) of ischemic heart disease patients with reduced left ventricular ejection fraction. We did not find significant difference between HFrEF and HFpEF in time to new onset heart failure. Systolic blood pressure, diastolic blood pressure, diabetes, left atrium and diastolic left ventricular dimension had significant association with new onset HFrEF on univariate regression analysis. Whereas new onset HFpEF was significantly associated with age, sex, presence of hypertension, Systolic blood pressure and diastolic left ventricular dimension. On cox regression analysis diastolic left ventricular dimension was associated with both new onset HFpEF and HFrEF. Age, diabetes, and dimension of left atrium were also associated with HFrEF.Conclusion: This cohort study in ischemic heart disease patients suggests a key role for the diastolic left ventricular dimension, left atrium size, diabetes, sex and age as predictors of new onset HFrEF and HFpEF. Strategies directed to prevention and early treatment of diabetes, dilatation of left ventricle and left atrium may prevent a considerable proportion of HFrEF or HFpEF.


Antecedentes: Los predictores ecocardiográficos de nuevos eventos de insuficiencia cardiaca en pacientes con cardiopatía isquémica con fracción de eyección ventricular preservada (HFpEF) o con fracción de eyección ventricular reducida (HFrEF) no son bien conocidos en la Africa etíope y subsahariana.Métodos: Doscientos veintiocho pacientes con cardiopatía isquémica fueron reclutados y seguidos retrospectivamente. Se realizaron análisis sobre las características clínicas y ecocardiográficas basales de los pacientes, así como los factores de riesgo para un nuevo evento de HFpEF y un nuevo evento de HFrEF. Los criterios de exclusión fueron insuficiencia cardíaca conocida al inicio del estudio y aquellos que no tenían datos de ecocardiografía.Resultados: Durante el período de seguimiento, la insuficiencia cardíaca se desarrolló en el 62,2% (61/98) de pacientes con cardiopatía isquémica con fracción de eyección ventricular izquierda preservada y en el 70,1% (92/130) de pacientes con cardiopatía isquémica con fracción de eyección ventricular izquierda reducida. No encontramos diferencias significativas entre HFrEF y HFpEF en el tiempo hasta la nueva aparición de insuficiencia cardíaca. La presión arterial sistólica, la presión arterial diastólica, la diabetes y las dimensiones de la aurícula iquierda y del ventrículo izquierdo en diástole tuvieron una asociación significativa con nuevos eventos de HFrEF en el análisis de regresión univariada. Mientras que un nuevo evento de HFpEF se asoció significativamente con la edad, el sexo, la presencia de hipertensión, la presión arterial sistólica y la dimensión ventricular izquierda diastólica. En el análisis de regresión de cox, la dimensión ventricular izquierda diastólica se asoció con HFpEF de nuevo inicio y HFrEF. La edad, la diabetes y la dimensión de la aurícula izquierda también se asociaron con HFrEF. Conclusión: Este estudio de cohorte en pacientes con cardiopatía isquémica sugiere un papel clave para la dimensión ventricular izquierda diastólica, el tamaño de la aurícula izquierda, la diabetes, el sexo y la edad como predictores de un nuevo evento de HFrEF y HFpEF. Las estrategias dirigidas a la prevención y el tratamiento temprano de la diabetes, la dilatación del ventrículo izquierdo y la aurícula izquierda pueden prevenir una proporción considerable de HFrEF o HFpEF.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Echocardiography/methods , Myocardial Ischemia/diagnostic imaging , Stroke Volume , Tobacco Use Disorder , Multivariate Analysis , Predictive Value of Tests , Regression Analysis , Retrospective Studies , Cohort Studies , Follow-Up Studies , Ventricular Function, Left , Age Factors , Myocardial Ischemia/physiopathology , Risk Assessment/methods , Heart Disease Risk Factors
2.
Säo Paulo med. j ; 139(2): 170-177, Mar.-Apr. 2021. tab, graf
Article in English | LILACS | ID: biblio-1181006

ABSTRACT

ABSTRACT BACKGROUND: Healthcare institutions are confronted with large numbers of patient admissions during large-scale or long-term public health emergencies like pandemics. Appropriate and effective triage is needed for effective resource use. OBJECTIVES: To evaluate the effectiveness of the Pandemic Medical Early Warning Score (PMEWS), Simple Triage Scoring System (STSS) and Confusion, Uremia, Respiratory rate, Blood pressure and age ≥ 65 years (CURB-65) score in an emergency department (ED) triage setting. DESIGN AND SETTING: Retrospective study in the ED of a tertiary-care university hospital in Düzce, Turkey. METHODS: PMEWS, STSS and CURB-65 scores of patients diagnosed with COVID-19 pneumonia were calculated. Thirty-day mortality, intensive care unit (ICU) admission, mechanical ventilation (MV) need and outcomes were recorded. The predictive accuracy of the scores was assessed using receiver operating characteristic curve analysis. RESULTS: One hundred patients with COVID-19 pneumonia were included. The 30-day mortality was 6%. PMEWS, STSS and CURB-65 showed high performance for predicting 30-day mortality (area under the curve: 0.968, 0.962 and 0.942, respectively). Age > 65 years, respiratory rate > 20/minute, oxygen saturation (SpO2) < 90% and ED length of stay > 4 hours showed associations with 30-day mortality (P < 0.05). CONCLUSIONS: CURB-65, STSS and PMEWS scores are useful for predicting mortality, ICU admission and MV need among patients diagnosed with COVID-19 pneumonia. Advanced age, increased respiratory rate, low SpO2 and prolonged ED length of stay may increase mortality. Further studies are needed for developing the triage scoring systems, to ensure effective long-term use of healthcare service capacity during pandemics.


Subject(s)
Humans , Male , Female , Aged , Aged, 80 and over , Pneumonia/diagnosis , Pneumonia/epidemiology , Triage/methods , Risk Assessment/methods , Emergency Service, Hospital/statistics & numerical data , Early Warning Score , COVID-19/therapy , Turkey , Uremia/etiology , Uremia/epidemiology , Blood Pressure , Retrospective Studies , Respiratory Rate/physiology , Pandemics , SARS-CoV-2 , COVID-19/diagnosis , COVID-19/epidemiology
3.
Int. j. morphol ; 38(6): 1645-1650, Dec. 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1134492

ABSTRACT

RESUMEN: El aumento sostenido en la prevalencia de sobrepeso y obesidad en niños, niñas y adolescentes, causa alarma en la comunidad científica, que observa incrementos importantes en las enfermerdades asociadas a Síndrome Metabólico (SM), en la vida adulta. Chile presenta un 75 % con sobrepeso y obesidad en la población adulta y un 50,9 % en la población estudiantil, con un 66,2 % de sedentarismo. Los objetivos de este trabajo fueron determinar los perfiles antropométricos y su asociación a riesgo metabólico en adolescentes de colegio particular subvencionado de Arica-Chile. El total de los alumnos de enseñanza media, n= 810 (mujeres n= 437 y hombres n= 373), fueron evaluados según: peso, talla, perímetro de cintura, índice cintura-talla (ICT), índice de masa corporal (IMC). A todos ellos se les calculó el riesgo metabólico según protocolos de Ashwell & Gibson (2016) y el IMC según fórmula de Quetelet. Los datos fueron analizados en estadístico para tendencia central, dispersión y porcentajes. Para correlación se utilizó test de Pearson (r>0,5). Los resultados muestran que un 44,1 % de las mujeres y un 37,2 % de los hombres presentan sobrepeso y obesidad. El riesgo metabólico general de la población en estudio fue de 24,6 % (24,7 % y 24,4 % en mujeres y hombres respectivamente). Se observó una alta correlación entre PC / ICT (r= 0,92), IMC / ICT (r= 0,86) y Peso / PC (r= 0,87). Se concluye que las y los adolescentes presentan valores antropométricos alterados que indican altos índices de riesgos metabólicos. Los parámetros más alterados se observan en el segundo año de enseñanza media con porcentajes de sobrepeso y obesidad de 49,1 % en las mujeres versus 33,8 % en los hombres. Independientemente, los hombres presentaron mejores índices morfométricos que las mujeres. Se observaron altas correlaciones (r> 0,5) en todos los parámetros en estudio, asociados a riesgo metabólico. Se sugiere enfocar las intervenciones educativas según sello de vida saludable, incentivando la actividad física y mejorar los hábitos alimenticios en las y los adolescentes escolarizados.


SUMMARY: The sustained increase in the prevalence of overweight and obesity in children and adolescents causes alarm in the scientific community, who observe significant increases in diseases associated with Metabolic Syndrome (MS), in adult life. Chile presents 75 % with overweight and obesity in the adult population and 50.9 % in the student population and with 66.2 % of sedentary lifestyle. The objectives of this work were to determine the anthropometric profiles and their association with metabolic risk in adolescents from a subsidized private school in Arica-Chile. The total of high school students, n = 810 (women n = 437 and men n = 373), were evaluated according to: weight, height, waist circumference, waist-height index (WHI), body mass index (BMI). Metabolic risk was calculated for all of them according to Ashwell & Gibson protocols and BMI according to Quetelet's formula. The data were analyzed in statistics for central tendency, dispersion, and percentages. Pearson test (r> 0.5) was used for correlation. The results show that 44.1 % of women and 37.2 % of men are overweight and obese. The general metabolic risk of the study population was 24.6 % (24.7 % and 24.4 % in women and men, respectively). A high correlation was observed between WC / WHI (r = 0.92), BMI / WHI (r = 0.86) and Weight / WC (r = 0.87). It is concluded that adolescents present altered anthropometric values that indicate high rates of metabolic risks. The most altered parameters were observed in the second year of secondary education with percentages of overweight and obesity of 49.1 % in women versus 33.8 % in men. Regardless, males presented better morphometric indices than females. High correlations (r> 0.5) were observed in all the parameters under study, associated with metabolic risk. It is suggested to focus educational interventions according to the seal of healthy living, encouraging physical activity and improving eating habits in school adolescents.


Subject(s)
Humans , Male , Female , Adolescent , Anthropometry , Risk Assessment/methods , Sedentary Behavior , Metabolic Diseases/etiology , Body Mass Index , Chile , Cross-Sectional Studies , Risk Factors , Education, Primary and Secondary , Overweight , Obesity
4.
Rev. chil. enferm. respir ; 36(2): 85-93, jun. 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1138539

ABSTRACT

INTRODUCCIÓN: En Chile, se estima que 8,5% de los adultos tiene riesgo elevado de síndrome de apnea e hipopnea obstructiva del sueño (SAHOS). OBJETIVO: Estimar el riesgo de SAHOS en funcionarios de la salud. MATERIAL Y MÉTODO: Se consignaron los datos clínicos, antropométricos, presión arterial, cuestionarios STOP-Bang (CSB), índice de Flemons y escalas de Epworth y de Thornton en trabajadores de Clínica Dávila, Santiago, Chile. RESULTADOS: Se evaluaron 1.332 funcionarios, 77,1% mujeres, circunferencia de cuello: 35,7 ± 3,7 cm (26-54), circunferencia de cintura: 89,3 ± 3,7 cm, e índice de masa corporal: 27,5 ± 4,5 (17,5-49,4) kg/m2; 42% tenía sobrepeso y 26% obesidad. El Cuestionario SB los clasificó en tres categorías: Riesgo alto (RA): 43 funcionarios (3,2%), 50 ± 10,5 años; riesgo moderado: 215 (16,1%), 45,6 ± 11,4 años y riesgo bajo: 1.074 (80,6%), 36,2 ± 10,6 años. En hombres, la edad y los puntajes de los cuestionarios de sueño fueron diferentes en las tres categorías de riesgo (p = 0,003 y 0,001). En mujeres, los puntajes de los cuestionarios fueron distintos en los tres grupos de riesgo, no hubo diferencias en la escala de Epworth (p = 0,274), ni en la edad (p = 0,08). La escala Mallampati no permitió predecir el riesgo de SAHOS en ambos sexos. CONCLUSIONES: El cuestionario SB identificó a 9,8% de los hombres con riesgo alto de SAHOS. En los hombres, la edad, cuestionario SB, Flemons, Epworth y Thornton, fueron diferentes en las tres categorías de riesgo de SAHOS. En las mujeres, la edad y escala de Epworth fueron similares en las tres categorías de riesgo.


INTRODUCTION: In Chile, it is estimated that 8.5% of adults are at high risk of Obstructive Sleep Apnea (OSA). OBJECTIVE: To estimate the risk of OSA in health workers. MATERIAL AND METHOD: clinical and anthropometric data, blood pressure, STOP-Bang (CSB) questionnaires, Flemons index and Epworth and Thornton scales were assessed in workers from Clínica Dávila, Santiago, Chile. RESULTS: 1,332 workers were evaluated, 77.1% women, neck circumference: 35.7 ± 3.7 cm (26-54), waist circumference: 89.3 ± 3.7 cm, and body mass index: 27.5 ± 4.5 (17.5-49.4) kg/m2; 42% were overweight and 26% obese. The SB Questionnaire classified them into three risk categories: High risk (HR): 43 workers (3.2%), 50 ± 10.5 years-old; moderate risk: 215 (16.1%), 45.6 ± 11.4 years-old and low risk: 1,074 (80.6%), 36.2 ± 10.6 years-old. In men, age and sleep questionnaire scores were different in the three risk categories (p = 0.003 and 0.001). In women, the sleep questionnaire scores were different in the three risk groups, there were no differences in the Epworth scale (p = 0.274), nor in age (p = 0.08). The Mallampati scale did not allow predict OSA risk in both sexes. CONCLUSIONS: The SB questionnaire identified 9.8% of the men with high risk of OSA. In men, age, SB questionnaire, Flemons index, Epworth and Thornton scale, were different in the three OSA risk categories. In women, the age and Epworth scale were similar in the different risk categories.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged , Young Adult , Health Personnel , Sleep Apnea, Obstructive/epidemiology , Body Mass Index , Logistic Models , Chile , Anthropometry , Prevalence , Prospective Studies , Surveys and Questionnaires , Risk Factors , Age Factors , Risk Assessment/methods , Forecasting
5.
Arq. bras. cardiol ; 114(5): 795-802, maio 2020. tab, graf
Article in Portuguese | LILACS, SES-SP | ID: biblio-1131233

ABSTRACT

Resumo Fundamento Múltiplos sistemas de pontuação têm sido elaborados para calcular o risco de eventos cardiovasculares adversos maiores (MACE) em pacientes com dor no peito. Não há dados que avaliem se o escore HEART tem um desempenho superior a TIMI e GRACE para a predição de MACE, especialmente na era de troponina I de alta sensibilidade e em uma população exclusivamente latino-americana. Objetivo Comparar o desempenho dos escores HEART, TIMI e GRACE para a predição de MACE em 30 dias de acompanhamento, em pacientes atendidos com dor no peito no departamento de emergência. Métodos Os escores HEART, TIMI e GRACE foram analisados em 519 pacientes com dor no peito no departamento de emergência. O desfecho primário foi a ocorrência de MACE no período de 30 dias. O desempenho do escore HEART foi comparado com o dos escores TIMI e GRACE utilizando o teste de DeLong, considerando estatisticamente significativos os valores de p de 0,05. Resultados Um total de 224 pacientes (43%) apresentaram MACE no período de 30 dias. A estatística C para os escores HEART, TIMI e GRACE foi de 0,937, 0,844 e 0,797 respectivamente (p < 0,0001). Uma pontuação de 3 ou menos no escore HEART apresentou uma sensibilidade de 99,5% e um valor preditivo negativo de 99% para classificar pacientes de baixo risco de maneira correta; ambos os valores foram mais elevados do que aqueles obtidos pelos outros escores. Conclusão O escore HEART, em um período de 30 dias, prediz eventos cardiovasculares, mais eficazmente, em comparação com os outros escores. Troponinas de alta sensibilidade mantêm a superioridade previamente demonstrada deste escore. Este escore oferece uma identificação mais precisa dos pacientes de baixo risco. (Arq Bras Cardiol. 2020; [online].ahead print, PP.0-0)


Abstract Background Multiple scoring systems have been designed to calculate the risk of major adverse cardiovascular events (MACE) in patients with chest pain. There is no data on whether the HEART score outperforms TIMI and GRACE in the prediction of MACE, especially in the era of high-sensitivity troponin assay and in an exclusively Latin-American population. Objective To compare the performance of the HEART, TIMI, and GRACE scores for predicting major cardiovascular events at 30 days of follow-up, in patients who consult for chest pain in the emergency department. Methods HEART, TIMI, and GRACE scores were analyzed in 519 patients with chest pain at the emergency department. The primary endpoint was the occurrence of MACE within 30 days. The performance of the HEART score was compared with the TIMI and GRACE scores using the DeLong test with p values of 0.05 considered statistically significant. Results A total of 224 patients (43%) had MACE at 30 days. The C statistic for the HEART, TIMI, and GRACE score was 0.937, 0.844, and 0.797 respectively (p < 0.0001). A HEART score of 3 or less had a sensitivity of 99.5% and a negative predictive value of 99% to classify low risk patients correctly; both values were higher than those obtained by the other scores. Conclusion The HEART score more effectively predicts cardiovascular events at 30 days of follow-up compared to the other scores. High-sensitivity troponins maintain this score's previously demonstrated superiority. This score offers more precise identification of low-risk patients. (Arq Bras Cardiol. 2020; [online].ahead print, PP.0-0)


Subject(s)
Humans , Male , Female , Chest Pain/diagnosis , Cardiovascular Diseases/diagnosis , Risk Assessment/methods , Acute Coronary Syndrome/diagnosis , Heart Diseases/diagnosis , Troponin , Severity of Illness Index , Predictive Value of Tests , Prospective Studies , Triage/methods , Emergency Service, Hospital
6.
Med. infant ; 27(1): 17-24, Marzo de 2020. tab
Article in Spanish | LILACS, BINACIS, UNISALUD | ID: biblio-1118590

ABSTRACT

Introducción: El niño hospitalizado se encuentra en estado de vulnerabilidad nutricional. El tamizaje nutricional permite identificar malnutrición y/o el riesgo de desarrollarla, para realizar un abordaje precoz. El Área de Alimentación del Hospital Garrahan desarrolló la "Herramienta de Tamizaje Nutricional Pediátrico" (HTNP), dada la falta de consenso sobre un estándar de oro y para ajustar criterios a la población asistida. El objetivo de esta investigación fue su validación para niños en cuidados intermedios/ moderados. Métodos: estudio prospectivo, descriptivo y transversal. Entre agosto de 2016 y abril de 2018 se reclutaron niños de 1 a 18 años internados en salas de cuidados intermedios/moderados seleccionadas, que cumplieran los criterios de inclusión. Se aplicaron: la HTNP y la valoración nutricional global subjetiva (VNGS) como prueba de comparación. La HTNP consta de tres criterios: Patología de base y motivo de internación- Disminución de peso- Deterioro de la actitud alimentaria. Se define riesgo nutricional si se cumple con dos criterios. Se analizaron: Sensibilidad, especificidad, valor predictivo positivo (VPP) y valor predictivo negativo (VPN), factibilidad y reproducibilidad. Resultados: Se evaluaron 745 niños (50,1% sexo femenino; mediana de edad: 7,2 años). La HTNP detectó riesgo nutricional en 50,7% (n378) de los niños y la VNGS en 48,7% (n363). La HTNP presentó: Sensibilidad 87,3% (IC95% 83,8-90,9), Especificidad 84,0% (IC95% 80,2-87,8), VPP 83,9% (IC95%: 80,0­87,7) y VPN 87,5% (IC95%: 83,9-91,0). Del análisis de reproducibilidad con dos evaluadores independientes (n42) se obtuvo coeficiente kappa de 0,91 (0,74-1,0) y 0,78 (0,5-1,0) respectivamente. Su implementación llevo un promedio de tres minutos y medio (1-5 minutos). Conclusión: La HTNP es un instrumento simple, reproducible, práctico y factible de implementar para identificar pacientes en riesgo nutricional (AU)


Introduction: Hospitalized children are nutritionally vulnerable. Nutritional screening may identify malnutrition and/or the risk of developing malnutrition in order to start early intervention. The Food Services Area of Garrahan Hospital has developed a "Pediatric Nutritional Screening Tool (PNST) because of the lack of consensus on a gold standard and to finetune the criteria to the care population. The aim of this study was to validate the tool in children in intermediate/moderate care. Methods: A prospective, descriptive, cross-sectional study was conducted. Between August 2016 and April 2018 children from 1 to 18 years of age who met the inclusion criteria were enrolled on selected intermediate/ moderate care wards. The PNST was administered together with the Subjective Global Assessment (SGA) as a comparison test. The PNST consists of three criteria: Underlying disease and reason for admission- Weight loss- Deterioration of eating behavior. A patient was defined as being at nutritional risk was defined if two criteria were met. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV), feasibility, and reproducibility were analyzed. Results: 745 children (50.1% female; median age: 7.2 years) were assessed. The PNST detected nutritional risk in 50.7% (n378) and the SGA in 48,7% (n363) of the children. The PNST showed: Sensitivity 87.3% (95%CI: 83.8-90.9), specificity 84.0% (95%CI: 80.2-87.8), PPV 83.9% (95%CI: 80.0­87.7), and NPV 87.5% (95%CI: 83,9-91,0). In a reproducibility analysis with two independent evaluators (n42) kappa coefficients of 0.91 (0.74-1.0) and 0.78 (0.5-1.0) were obtained, respectively. Administration of the tool took a mean of 3.5 inutes (1-5 minutes). Conclusion: The PNST is a simple, reproducible, practical, and feasible tool to use for the identification of patients at nutritional risk (AU)


Subject(s)
Humans , Infant , Child, Preschool , Child , Adolescent , Child Nutrition Disorders/diagnosis , Nutrition Assessment , Child, Hospitalized , Mass Screening/methods , Nutritional Status , Risk Assessment/methods , Cross-Sectional Studies , Prospective Studies
8.
Braz. j. infect. dis ; 24(1): 34-43, Feb. 2020. tab, graf
Article in English | LILACS | ID: biblio-1089324

ABSTRACT

ABSTRACT Introduction: Multidrug-resistant gram-negative rods (MDR GNR) represent a growing threat for patients with cancer. Our objective was to determine the characteristics of and risk factors for MDR GNR bacteremia in patients with cancer and to develop a clinical score to predict MDR GNR bacteremia. Material and Methods: Multicenter prospective study analyzing initial episodes of MDR GNR bacteremia. Risk factors were evaluated using a multiple logistic regression (forward-stepwise selection) analysis including variables with a p < 0.10 in univariate analysis. Results: 394 episodes of GNR bacteremia were included, with 168 (42.6 %) being MDR GNR. Five variables were identified as independent risk factors: recent antibiotic use (OR = 2.8, 95 % CI 1.7-4.6, p = 0.001), recent intensive care unit admission (OR = 2.9, 95 % CI 1.1-7.8, p = 0.027), hospitalization ≥ 7 days prior to the episode of bacteremia (OR = 3.5, 95 % CI 2-6.2, p = 0.005), severe mucositis (OR = 5.3, 95 % CI 1.8-15.6, p = 0.002), and recent or previous colonization/infection with MDR GNR (OR = 2.3, 95 % CI 1.2-4.3, p = 0.028). Using a cut-off value of two points, the score had a sensitivity of 66.07 % (95 % CI 58.4-73.2 %), a specificity of 77.8 % (95 % CI 71.4-82.7 %), a positive predictive value of 68 % (95 % CI 61.9-73.4 %), and a negative predictive value of 75.9 % (95 % CI 71.6-79.7 %). The overall performance of the score was satisfactory (AUROC 0.78; 95 % CI 0.73-0.82). In the cases with one or none of the risk factors identified, the negative likelihood ratio was 0.18 and the post-test probability of having MDR GNR was 11.68 %. Conclusions: With the growing incidence of MDR GNR as etiologic agents of bacteremia in cancer patients, the development of this score could be a potential tool for clinicians.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Young Adult , Gram-Negative Bacterial Infections/etiology , Bacteremia/etiology , Risk Assessment/methods , Drug Resistance, Multiple, Bacterial , Gram-Negative Bacteria/drug effects , Neoplasms/microbiology , Argentina , Time Factors , Logistic Models , Multivariate Analysis , Predictive Value of Tests , Prospective Studies , Risk Factors , Gram-Negative Bacterial Infections/drug therapy , Statistics, Nonparametric , Anti-Bacterial Agents/therapeutic use , Neoplasms/complications
9.
Article in English | WPRIM | ID: wpr-880299

ABSTRACT

BACKGROUND@#Need to a simple, available, accurate, comprehensive, and valid indicator is felt to assess thermal effects. Therefore, the present study was aimed to develop and validate the environmental heat strain risk assessment (EHSRA) index using structural equation modeling (SEM) based on empirical relations.@*METHODS@#This cross-sectional study was performed on 201 male workers in environments with various climatic conditions. The heart rate and tympanic temperature of the individuals were monitored at times of 30, 60, and 90 min after beginning the work. At these times, values of dry temperature, wet temperature, globe temperature, and air velocity were also measured and metabolism rate and clothing thermal insulation value were estimated. At the end, a theoretical model was depicted in AMOS software and obtained coefficients were applied to develop a novel index. The scores of this indicator were categorized into four risk levels via ROC curves and validate using linear regression analysis.@*RESULTS@#Indirect effect coefficients of the globe temperature, dry temperature, wet temperature, air velocity, metabolism, and clothing thermal insulation variables on the tympanic temperature were computed by 0.77, 0.75, 0.69, 0.24, 0.49, and 0.39, respectively. These coefficients were applied to develop the index. Optimal cut-off points of boundaries between risk levels included 12.02, 15.88, and 17.56. The results showed that the EHSRA index justified 75% of the variations of the tympanic temperature (R@*CONCLUSIONS@#The novel index possesses appropriate validity. It was suggested that this indicator is applied and validated in various environments in the next studies.


Subject(s)
Adult , Environmental Health/methods , Heat-Shock Response , Hot Temperature/adverse effects , Humans , Iran , Latent Class Analysis , Male , Middle Aged , Risk Assessment/methods , Young Adult
10.
Chinese Journal of Traumatology ; (6): 346-350, 2020.
Article in English | WPRIM | ID: wpr-879652

ABSTRACT

PURPOSE@#Boarding is a common problem in the emergency department (ED) and is associated with poor health care and outcome. Imam Khomeini Hospital is the main healthcare center in Urmia, a metropolis in the northwest of Iran. Due to the overcrowding and high patient load, we aim to characterize the rate, cause and consequence of boarding in the ED of this center.@*METHODS@#All medical records of patients who presented to the ED of Imam Khomeini Hospital from August 1, 2017 to August 1, 2018 were retrospectively analyzed. Patients with uncompleted records were excluded. Boarding was defined as the inability to transfer the admitted ED patients to a downstream ward in ≥2 h after the admission order. Demographic data, boarding rate, mortality and triage levels (1-5) assessed by emergency severity index were collected and analyzed. The first present time of patients was classified into 4 ranges as 0:00-5:59, 6:00-11:59, 12:00-17:59 and 18:00-23:59. Descriptive, parametric and non-parametric statistical tests were performed and the risk of boarding was determined by Pearson Chi-square test.@*RESULTS@#Demographic data analysis showed that 941 (58.5%) male and 667 (41.5%) female, altogether 1608 patients were included in this study. Five patients (0.3%) died. The distribution of patients with the triage levels 1-5 was respectively 79 (4.9%), 1150 (71.5%), 374 (23.3%), 4 (0.2%) and 0 (0%). Most patients were of level 2. Only 75 (4.7%) patients required intensive care. The majority of patients (84.2%) were presented at weekdays. The maximum patient load was observed between 12:00-17:59. Of the 1608 patients, 340 (21.1%) experienced boarding within a mean admission time of 13.70 h. Among the 340-boarded patients, 20.1% belonged to surgery, 12.1% to orthopedics, 10.9% to neurosurgery and 10.3% to neurology. The boarding rate was higher in females, patients requiring intensive care and those with low triage levels. Compared with the non-boarded, the boarded patients had a higher mean age.@*CONCLUSION@#The boarding rate is higher in the older and female patients. Moreover, boarding is dependent on the downstream ward sections: patients requiring surgical management experience the maximum boarding rate.


Subject(s)
Age Factors , Chi-Square Distribution , Cross-Sectional Studies , Crowding , Emergency Service, Hospital , Female , Hospital Mortality , Hospitalization/statistics & numerical data , Humans , Iran , Length of Stay , Male , Patient Admission , Retrospective Studies , Risk Assessment/methods , Risk Factors , Sex Factors , Time Factors , Triage
11.
Rev. saúde pública (Online) ; 54: 47, 2020. tab, graf
Article in English | LILACS, BBO | ID: biblio-1101873

ABSTRACT

ABSTRACT OBJECTIVE To use the advantages of a ratio scale with verbal anchors in order to measure the risk perception in the novel coronavirus infection, which causes covid-19, in a health belief model-based questionnaire, as well as its validity and reproducibility. METHOD We used the health belief model, which explores four dimensions: perceived susceptibility (five questions), perceived severity (five questions), perceived benefits (five questions), and perceived barriers (five questions). Additionally, we included a fifth dimension, called pro-health motivation (four questions). The questions composed an electronic questionnaire disseminated by social networks for an one-week period. Answers were quantitative values of subjective representations, obtained by a psychophysically constructed scale with verbal anchors ratio (CentiMax ® ). Mean time for total filling was 12 minutes (standard deviation = 1.6). RESULTS We obtained 277 complete responses to the form. One was excluded because it belonged to a participant under 18 years old. Reproducibility measures were significant for 22 of the 24 questions in our questionnaire (Cronbach's α = 0.883). Convergent validity was attested by Spearman-Brown's split half reliability coefficient (r = 0.882). Significant differences among groups were more intense in perceived susceptibility and severity dimensions, and less in perceived benefits and barriers. CONCLUSION Our health belief model-based questionnaire using quantitative measures enabled the confirmation of popular beliefs about covid-19 infection risks. The advantage in our approach lays in the possibility of quickly, directly and quantitatively identifying individual belief profiles for each dimension in the questionnaire, serving as a great ally for communication processes and public health education.


RESUMO OBJETIVO Neste estudo buscamos utilizar as vantagens de uma escala de razão por ancoragem verbal para medidas da percepção de risco de contágio pelo novo coronavírus, causador da covid-19, em um questionário baseado no modelo de crença em saúde, assim como avaliar sua validade e reprodutibilidade. MÉTODO Utilizamos o modelo de crença em saúde, o qual explora quatro dimensões: percepção individual de susceptibilidade percebida (cinco questões), severidade percebida (cinco questões), benefícios percebidos (cinco questões) e barreiras percebidas (cinco questões). Adicionalmente, incluímos uma quinta dimensão, a qual denominamos motivação pró-saúde (quatro questões). As questões definiram um questionário eletrônico que foi divulgado por redes sociais pelo período de uma semana. As respostas foram valores quantitativos de representações subjetivas, obtidas por meio de uma escala psicofísica de razão com ancoragem verbal (CentiMax ® ). O tempo médio total de preenchimento foi de 12 minutos (desvio-padrão = 1,6). RESULTADOS Obtivemos 277 respostas completas ao formulário. Uma foi excluída por se tratar de participante com menos de 18 anos de idade. Medidas de reprodutibilidade foram significantes para 22 das 24 questões de nosso questionário (α de Cronbach = 0,883). A validade convergente foi atestada pelo coeficiente de correlação de Spearman-Brown split half (r = 0,882). Diferenças significantes entre grupos foram encontradas mais intensamente nas dimensões susceptibilidade percebida e severidade percebida, e menos intensamente para benefícios percebidos e barreiras percebidas. CONCLUSÃO Nosso questionário baseado no modelo de crença em saúde utilizando medidas quantitativas permitiu evidenciar as crenças populares sobre os riscos de contágio por covid-19. A vantagem de nossa abordagem é a possibilidade de se identificar os perfis de crença individuais para cada dimensão do questionário de forma rápida, direta e quantitativa, podendo ser uma grande aliada em processos de comunicação e educação em saúde pública.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Aged , Young Adult , Pneumonia, Viral/psychology , Pneumonia, Viral/transmission , Surveys and Questionnaires/standards , Coronavirus Infections/psychology , Coronavirus Infections/transmission , Risk Assessment/methods , Culture , Betacoronavirus , Reference Values , Socioeconomic Factors , Brazil , Reproducibility of Results , Risk Factors , Pandemics , SARS-CoV-2 , COVID-19 , Middle Aged , Models, Psychological
12.
Rev. bras. epidemiol ; 23: e200026, 2020. tab
Article in Portuguese | LILACS | ID: biblio-1101595

ABSTRACT

RESUMO: Objetivo: Classificar os medicamentos usados durante o parto quanto aos riscos na amamentação, utilizando diferentes fontes e verificando suas discordâncias. Métodos: Estudo transversal inserido na coorte de nascimentos de Pelotas de 2015. Coletaram-se informações sobre o uso de medicamentos, classificando-os quanto ao risco de acordo com: manual do Ministério da Saúde (MS), Organização Mundial da Saúde (OMS), classificação de Newton e Hale e Academia Americana de Pediatria (AAP). Resultados: Participaram 1.409 mães, utilizando 14.673 medicamentos, sendo 143 fármacos diferentes, dos quais 28 tiveram classificação de risco na amamentação discordante. Entre aqueles com classificação discordante estão morfina (64%), classificada pela AAP e OMS como compatível e pelo MS e por Newton e Hale como criterioso; hioscina (23%), criterioso pelo MS e compatível (A) pela AAP; e metoclopramida (18%), compatível pelo MS, de efeitos desconhecidos (D) pela AAP e evitado de acordo com a OMS. Do total de medicamentos, 49,7% foi classificado como compatível com a amamentação. Quase a totalidade das mulheres utilizou ocitocina (97,4%), seguida de lidocaína (75%), cetoprofeno (69%), cefalotina (66%) e diclofenaco (65%), classificados como compatíveis. Conclusão: Houve amplo uso de medicamentos pelas mães durante a internação para o parto, a maioria deles classificada no mesmo grau de risco, e quase a metade classificada como compatível com a amamentação, porém houve discordância entre as fontes para 19,6% dos medicamentos analisados, o que pode colocar em risco a saúde do lactente ou deixar dúvida quanto ao uso do medicamento ou à prática da amamentação.


ABSTRACT: Objective: To classify the drugs used during childbirth in relation to risks in breastfeeding, by using different sources of information and determining their disagreements. Methods: Cross-sectional study, within the 2015 Pelotas Birth Cohort. Information about the use of drugs was collected, classified and compared regarding risk according to: 1) Brazil Ministry of Health Manual (MS), 2) World Organization (WHO), 3) Newton and Hale's classification and 4) American Academy of Pediatrics (AAP). Results: A total of 1,409 mothers participated, and they had used 14,673 medicines, with 143 different drugs, of which 28 showed discordant classification with regard to breastfeeding risk. These 28 drugs included the following: morphine (64%), classified by AAP and WHO as compatible and as judicious use use by MS and Newton and Hale; hyoscine (23%), classified as judicious use by MS and compatible (A) by AAP; and metoclopramide (18%), classified as compatible by MS, of effects unknown (D) by AAP, and should be avoided according to WHO. Of the total drugs, 49.7% were classified as compatible during breastfeeding. Almost all women used oxytocin (97.4%), followed by lidocaine (75%), ketoprofen (69%), cephalothin (66%) and diclofenac (65%), which were classified as compatible. Conclusion: There was extensive use of drugs by mothers in labor during admission, most of the drugs being classified at the same risk and almost half classified as compatible with breastfeeding. However, there was disagreement between the sources for 19.6% of the drugs analyzed, which could endanger the infant's health or leave doubts about the use of the drug or breastfeeding.


Subject(s)
Humans , Female , Adolescent , Adult , Young Adult , Breast Feeding , Risk Assessment/methods , Delivery, Obstetric/adverse effects , Drug-Related Side Effects and Adverse Reactions , Drug Utilization/classification , Hospitalization , World Health Organization , Brazil , Cross-Sectional Studies , Risk Factors , Contraindications, Drug , Middle Aged , Milk, Human/drug effects , Mothers
13.
Einstein (Säo Paulo) ; 18: eAO5480, 2020. tab, graf
Article in English | LILACS | ID: biblio-1133761

ABSTRACT

ABSTRACT Objective: To propose a preliminary artificial intelligence model, based on artificial neural networks, for predicting the risk of nosocomial infection at intensive care units. Methods: An artificial neural network is designed that employs supervised learning. The generation of the datasets was based on data derived from the Japanese Nosocomial Infection Surveillance system. It is studied how the Java Neural Network Simulator learns to categorize these patients to predict their risk of nosocomial infection. The simulations are performed with several backpropagation learning algorithms and with several groups of parameters, comparing their results through the sum of the squared errors and mean errors per pattern. Results: The backpropagation with momentum algorithm showed better performance than the backpropagation algorithm. The performance improved with the xor. README file parameter values compared to the default parameters. There were no failures in the categorization of the patients into their risk of nosocomial infection. Conclusion: While this model is still based on a synthetic dataset, the excellent performance observed with a small number of patterns suggests that using higher numbers of variables and network layers to analyze larger volumes of data can create powerful artificial neural networks, potentially capable of precisely anticipating nosocomial infection at intensive care units. Using a real database during the simulations has the potential to realize the predictive ability of this model.


RESUMO Objetivo: Propor um modelo preliminar de inteligência artificial, baseado em redes neurais artificiais, para previsão do risco de infecção hospitalar em unidades de cuidado intensivo. Métodos: Foi usada uma rede neural artificial, que utiliza aprendizagem supervisionada. A geração dos conjuntos de dados baseia-se em dados derivados do sistema Japanese Nosocomial Infection Surveillance . Estudamos como o Java Neural Network Simulator aprende a categorizar esses pacientes para prever o respectivo risco de infecção hospitalar. As simulações são realizadas com diferentes algoritmos de aprendizagem por retropropagação e diversos grupos de parâmetros, comparando-se os resultados com base na soma dos erros quadráticos e erros médios por padrão. Resultados: O algoritmo de retropropagação com momentum mostrou desempenho superior ao do algoritmo de retropropagação. O desempenho foi melhor com os valores de parâmetros do arquivo xor. README em comparação aos parâmetros default . Não houve falhas na categorização de pacientes quanto ao respectivo risco de infecção hospitalar. Conclusão: Embora esse modelo se baseie em um conjunto de dados sintéticos, o excelente desempenho observado com um pequeno número de padrões sugere que o uso de números maiores de variáveis e camadas de rede para analisar volumes maiores de dados pode criar redes neurais artificiais poderosas, possivelmente capazes de prever com precisão o risco de infecção hospitalar em unidades de cuidado intensivo. O uso de um banco de dados real durante as simulações torna possível a realização da capacidade preditiva desse modelo.


Subject(s)
Humans , Artificial Intelligence , Cross Infection , Neural Networks, Computer , Risk Assessment/methods , Algorithms , APACHE , Intensive Care Units
14.
Einstein (Säo Paulo) ; 18: eAO5075, 2020. tab
Article in English | LILACS | ID: biblio-1101100

ABSTRACT

ABSTRACT Objective To evaluate the nutritional risk factors in patients eligible for hematopoietic stem cell transplantation. Methods A cross-sectional, descriptive study conducted with patients recruited from an hematology outpatient clinic. Study variables included demographic and clinical data, patient-generated global subjective assessment findings, anthropometric indicators, food intake and oxidative stress levels. The level of significance was set at 5% (p<0.05). Results The sample comprised 72 patients, mean age of 48.93 years (14.5%). Multiple myeloma was the most prevalent condition (51.4%) in this sample. Most patients (55.6%) were overweight according to body mass index and at risk of cardiovascular disease according to waist circumference, conicity index and percentage of body fat. Sarcopenia was associated with risk of cardiovascular disease, hip-to-waist ratio (p=0.021), muscle strength depletion (p<0.001), food intake (p=0.023), reduced functional capacity (p=0.048), self-reported well-nourished status; p=0.044) and inadequate vitamin B6 (p=0.022) and manganese (p=0.026) intake. Elevated oxidative stress, detected in 33.3% of patients in this sample, was not associated with sarcopenia. Conclusion Most patients in this sample were overweight and sarcopenic. Lean mass depletion was associated with risk of cardiovascular disease, reduced muscle strength, food intake changes, reduced functional capacity, self-reported well-nourished status and inadequate intake of vitamin B6 and manganese, but not with oxidative stress.


RESUMO Objetivo Avaliar os fatores de riscos nutricionais em pacientes pré-transplante de célula-tronco hematopoiética. Métodos Estudo transversal, descritivo, realizado com pacientes de um ambulatório de hematologia. As variáveis estudadas foram demográficas, dados clínicos, avaliação subjetiva global produzida pelo próprio paciente, indicadores antropométricos, ingestão alimentar e estresse oxidativo. Os dados foram considerados estatisticamente significativos quando p<0,05. Resultados A amostra do estudo foi constituída por 72 pacientes, com média de idade de 48,93 (14,5%) anos e com mieloma múltiplo (51,4%) como a patologia mais prevalente. Conforme índice de massa corporal, 55,6% dos pacientes encontravam-se com excesso de peso. De acordo com a circunferência da cintura, índice de conicidade e percentual de gordura corporal, houve prevalência de risco para doença cardiovascular. A sarcopenia foi associada ao risco de doença cardiovascular pela relação cintura/quadril (p=0,021), depleção da força muscular (p<0,001), além da ingestão alimentar (p=0,023), da capacidade funcional reduzida (p=0,048) e do diagnóstico de "bem nutrido" (p=0,044), conforme a avaliação subjetiva global, e com consumo inadequado de vitamina B6 (p=0,022) e de manganês (p=0,026). Dentre os avaliados, 33,3% apresentaram estresse oxidativo elevado sem associação com sarcopenia. Conclusão Pacientes do pré-transplante se apresentam, em sua maioria, com excesso de peso, mas com sarcopenia, estando essa ausência de massa magra associada a risco de doença cardiovascular, depleção da força muscular, alteração da ingestão alimentar, redução da capacidade funcional, classificação de "bem nutrido", segundo a avaliação subjetiva global e consumo inadequado de vitamina B6 e manganês, não estando associada a estresse oxidativo.


Subject(s)
Humans , Male , Female , Adult , Nutrition Assessment , Risk Assessment/methods , Hematopoietic Stem Cell Transplantation/adverse effects , Energy Intake/physiology , Cardiovascular Diseases/etiology , Cardiovascular Diseases/physiopathology , Anthropometry , Nutritional Status/physiology , Cross-Sectional Studies , Risk Factors , Oxidative Stress/physiology , Eating/physiology , Overweight/complications , Overweight/physiopathology , Muscle Strength/physiology , Sarcopenia/complications , Sarcopenia/physiopathology , Middle Aged , Multiple Myeloma/surgery , Multiple Myeloma/physiopathology
15.
Summa psicol. UST ; 17(1): 11-19, 2020. tab
Article in Spanish | LILACS | ID: biblio-1129383

ABSTRACT

El presente estudio tuvo como objetivo detectar el nivel de riesgo por consumo de sustancias psicoactivas (SPA) en una muestra de 324 universitarios ingresantes a Psicología en Arequipa ­ Perú, siendo el 73.15% de sexo femenino y 26.85% masculino, con edades que fluctúan entre los 18 y 25 años. Se empleó para ello la prueba ASSIST elaborada por la Organización Mundial de la Salud (OMS), hallando que el 33.02%, 22.53% y 10.49% alcanza un nivel de riesgo moderado en el consumo de tabaco, bebidas alcohólicas y marihuana correspondientemente. Además, el 2.78% presentó un nivel de riesgo alto en el consumo de bebidas alcohólicas. Se concluye que las SPA más consumidas por dichos universitarios son bebidas alcohólicas y tabaco, y que aproximadamente 1 de cada 4 tiene un riesgo moderado a alto de tener problemas por el consumo de alcohol y tabaco


The objective of this study was to detect the level of risk due to consumption of psychoactive substances in a sample of 324 undergraduates entering Psychology in Arequipa - Peru, with 73.15% female and 26.85% male, and ages between 18 and 25 years. The ASSIST test prepared by the World Health Organization (WHO) detected that 33.02%, 22.53% and 10.49% reach a moderate level of risk in the consumption of tobacco, alcoholic beverages and marijuana correspondingly. Besides, 2.78% of a high level of risk in the consumption of alcoholic beverages, concluding that the SPA most consumed by these university students are alcoholic beverages and tobacco; that approximately 1 in 4 has a moderate to high risk of having problems with alcohol and tobacco consumption.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Young Adult , Students/psychology , Universities , Risk Assessment/methods , Substance-Related Disorders/epidemiology , Peru , Cannabis , Cross-Sectional Studies , Risk Factors , Substance-Related Disorders/diagnosis , Tobacco Use , Alcohol Drinking in College
16.
Rev Rene (Online) ; 21: 42053, 2020. ilus
Article in English, Portuguese | LILACS, BDENF | ID: biblio-1087338

ABSTRACT

Objetivo: descrever os elementos constitutivos do cuidado de enfermagem presentes nas escalas de avaliação do risco de lesão por pressão usadas em unidades de terapia intensiva. Métodos: trata-se de uma revisão integrativa da literatura a partir do LILACS, MEDLINE, SCIELO e BDENF. Os descritores utilizados para a busca foram Pressure Ulcer; Decubitus Ulcer; Prevention and Control; Prevention; Intensive Care Units. A amostra final foi constituída por 13 artigos científicos. Resultados: a escala mais utilizada entre os estudos analisados foi Braden. Os elementos constitutivos evidenciados foram avaliação estruturada do risco, avaliação da pele e tecidos, cuidados preventivos com a pele, nutrição, reposicionamento no leito, superfícies de apoio e cuidados com dispositivos médicos. Conclusão: a prevenção de lesões relacionadas às incontinências, avaliação nutricional, intervenções nutricionais com o objetivo de prevenir lesões e os cuidados relacionados a dispositivos médicos são elementos constitutivos do cuidado de enfermagem pouco explorados ou ausentes nas escalas avaliadas


Objective: to describe the constituent elements of nursing care present in the pressure injury risk assessment scales used in intensive care units. Methods: this is an integrative literature review based on LILACS, MEDLINE, SCIELO and BDENF. The descriptors used for the search were Pressure Ulcer; Decubitus Ulcer; Prevention and control; Preven-tion; Intensive Care Units. The final sample consisted of 13 scientific articles. Results: the Braden scale was the most used scale among the analyzed studies. The constituent ele-ments highlighted were structured risk assessment, skin and tissue assessment, preventive skin care, nutrition, re-positioning in bed, support surfaces, and care with medical device. Conclusion: the prevention of incontinence-related injuries, nutritional assessment, nutritional interventions aimed at preventing injuries and care with medical devices are constituent elements of nursing care still poorly explo-red or absent in the evaluated scales


Subject(s)
Humans , Pressure Ulcer/prevention & control , Intensive Care Units , Nutrition Assessment , Risk Assessment/methods , Pressure Ulcer/nursing , Equipment and Supplies, Hospital
17.
Rev. bras. ter. intensiva ; 31(4): 490-496, out.-dez. 2019. tab
Article in Portuguese | LILACS | ID: biblio-1058038

ABSTRACT

RESUMO Objetivo: Avaliar a concordância entre o escore NUTRIC modificado e o escore NUTRIC com proteína C-reativa na identificação de pacientes em risco nutricional e na predição da mortalidade entre pacientes críticos. Avaliou-se também o risco de óbito com agrupamento dos pacientes segundo o risco nutricional e a desnutrição detectada pela avaliação subjetiva global. Métodos: Estudo de coorte em pacientes admitidos em uma unidade de terapia intensiva. O risco nutricional foi avaliado por meio do escore NUTRIC modificado e uma versão do escore NUTRIC com proteína C-reativa. Aplicou-se avaliação subjetiva global para diagnóstico de desnutrição. Calculou-se a estatística de Kappa e construiu-se uma curva ROC considerando o NUTRIC modificado como referência. A validade preditiva foi avaliada considerando a mortalidade em 28 dias (na unidade de terapia intensiva e após a alta) como desfecho. Resultados: Estudaram-se 130 pacientes (63,05 ± 16,46 anos, 53,8% do sexo masculino). Segundo o NUTRIC com proteína C-reativa, 34,4% foram classificados como escore alto, enquanto 28,5% dos pacientes tiveram esta classificação com utilização do NUTRIC modificado. Segundo a avaliação subjetiva global, 48,1% dos pacientes estavam desnutridos. Observou-se concordância excelente entre o NUTRIC modificado e o NUTRIC com proteína C-reativa (Kappa = 0,88; p < 0,001). A área sob a curva ROC foi igual a 0,942 (0,881 - 1,000) para o NUTRIC com proteína C-reativa. O risco de óbito em 28 dias estava aumentado nos pacientes com escores elevados pelo NUTRIC modificado (HR = 1,827; IC95% 1,029 - 3,244; p = 0,040) e pelo NUTRIC com proteína C-reativa (HR = 2,685; IC95% 1,423 - 5,064; p = 0,002). Observou-se elevado risco de óbito nos pacientes com alto risco nutricional e desnutrição, independentemente da versão do NUTRIC aplicada. Conclusão: A concordância entre o escore NUTRIC modificado e o NUTRIC com proteína C-reativa foi excelente. Além disto, a combinação da avaliação com um escore NUTRIC mais avaliação subjetiva global pode aumentar a precisão para predição de mortalidade em pacientes críticos.


ABSTRACT Objective: To evaluate the concordance between the modified NUTRIC and NUTRIC with C-reactive protein instruments in identifying nutritional risk patients and predicting mortality in critically ill patients. The risk of death in patient groups was also investigated according to nutritional risk and malnutrition detected by subjective global assessment. Methods: A cohort study of patients admitted to an intensive care unit. Nutritional risk was assessed by modified NUTRIC and a version of NUTRIC with C-reactive protein. Subjective global assessment was applied to diagnose malnutrition. Kappa statistics were calculated, and an ROC curve was constructed considering modified NUTRIC as a reference. The predictive validity was assessed considering mortality in 28 days (whether in the intensive care unit or after discharge) as the outcome. Results: A total of 130 patients were studied (63.05 ± 16.46 years, 53.8% males). According to NUTRIC with C-reactive protein, 34.4% were classified as having a high score, while 28.5% of patients had this classification with modified NUTRIC. According to SGA 48.1% of patients were malnourished. There was excellent agreement between modified NUTRIC and NUTRIC with C-reactive protein (Kappa = 0.88, p < 0.001). The area under the ROC curve was equal to 0.942 (0.881 - 1.000) for NUTRIC with C-reactive protein. The risk of death within 28 days was increased in patients with high modified NUTRIC (HR = 1.827; 95%CI 1.029 - 3.244; p = 0.040) and NUTRIC with C-reactive protein (HR = 2.685; 95%CI 1.423 - 5.064; p = 0.002) scores. A high risk of death was observed in patients with high nutritional risk and malnutrition, independent of the version of the NUTRIC score applied. Conclusion: An excellent agreement between modified NUTRIC and NUTRIC with C-reactive protein was observed. In addition, combining NUTRIC and subjective global assessment may increase the accuracy of predicting mortality in critically ill patients.


Subject(s)
Humans , Male , Female , Adult , Aged , Aged, 80 and over , Nutrition Assessment , Malnutrition/epidemiology , Intensive Care Units , C-Reactive Protein/analysis , Nutritional Status , Reproducibility of Results , Cohort Studies , Longitudinal Studies , Critical Illness/mortality , Risk Assessment/methods , Malnutrition/mortality , Middle Aged
18.
Rev. bras. enferm ; 72(6): 1496-1503, Nov.-Dec. 2019.
Article in English | LILACS, BDENF | ID: biblio-1042194

ABSTRACT

ABSTRACT Objective: to describe the conception of justice of nurses and users regarding the Risk Classification in Emergency Unit; to analyze the conception of justice in the implementation of the Risk Classification in Emergency Unit from the user's recognition; to discuss, from Axel Honneth's Theory of Recognition, justice with the user in the Risk Classification in Emergency Unit. Method: qualitative research of descriptive, exploratory typology, which used action research as a method. Bardin's Content Analysis was carried out. Results: a category was created: "Justice versus Injustice" and three subcategories: "Autonomy/Freedom versus Heteronomy/Subordination"; "Communication versus Hermeneutic Problems"; "Contributions versus Conflicts". Final considerations: Embracement with Risk Classification presents difficulties in its interpretation and effectiveness; there are situations of disrespect that compete against the required ethics. Justice addressed by this study will be achieved by an emergency access system that meets user expectations, recognizing it as a subject of rights.


RESUMEN Objetivo: describir la concepción de justicia de enfermeros y usuarios en la Clasificación de Riesgo en Emergencia; analizar la concepción de justicia en la implementación de la Clasificación de Riesgo en la Emergencia a partir del reconocimiento del usuario; discutir, a partir de la Teoría del Reconocimiento de Axel Honneth, la justicia con el usuario en la Clasificación de Riesgo en Unidad de Emergencia. Método: investigación cualitativa de tipología descriptiva, exploratoria, que utilizó como método la investigación-acción. Análisis de Contenido de Bardin. Resultados: se organizó una categoría: "Justicia versus Injusticia" y tres subcategorías: "Autonomía/Libertad versus Heteronomía/Subordinación"; "Comunicación versus Problemas Hermenéuticos"; "Contribuciones versus Conflictos". Consideraciones finales: Acogida con Clasificación de Riesgo presenta dificultades en su interpretación y efectividad, con situaciones de incumplimiento que concurren contra la ética requerida. La justicia de que trata este estudio será alcanzada por un sistema de acceso a las emergencias que alcance las expectativas del usuario, reconociéndolo como sujeto de derechos.


RESUMO Objetivo: descrever a concepção de justiça de enfermeiros e usuários na Classificação de Risco em Emergência; analisar a concepção de justiça na implementação da Classificação de Risco na Emergência a partir do reconhecimento do usuário; discutir, a partir da Teoria do Reconhecimento de Axel Honneth, a justiça com o usuário na Classificação de Risco em Unidade de Emergência. Método: pesquisa qualitativa de tipologia descritiva, exploratória, que utilizou como método a pesquisa-ação. Análise de Conteúdo de Bardin. Resultados: foi organizada uma categoria: "Justiça versus Injustiça" e três subcategorias: "Autonomia/Liberdade versus Heteronomia/Subordinação"; "Comunicação versus Problemas Hermenêuticos"; "Contribuições versus Conflitos". Considerações finais: o Acolhimento com Classificação de Risco apresenta dificuldades em sua interpretação e efetividade, com situações de desrespeito que concorrem contra a ética requerida. A justiça de que trata esse estudo será alcançada por um sistema de acesso às emergências que atinja as expectativas do usuário, reconhecendo-o como sujeito de direitos.


Subject(s)
Humans , Female , Adult , Social Justice , Triage/methods , Risk Assessment/methods , Emergencies/classification , Emergency Service, Hospital , Problem Solving , Time Factors , Communication , Conflict, Psychological , Personal Autonomy , Qualitative Research , Dominance-Subordination , Educational Status , Hermeneutics , Freedom , Middle Aged , Nursing Staff, Hospital
19.
Medicina (B.Aires) ; 79(6): 438-444, dic. 2019. ilus, graf, tab
Article in English | LILACS | ID: biblio-1056751

ABSTRACT

Cardiovascular disease (CVD) is the leading cause of death in Argentina. Computer simulation models allow to extrapolate evidence to broader populations than the originally studied, over longer timeframes, and to compare different subpopulations. The Cardiovascular Disease Policy Model (CVDPM) is a computer simulation state transition model used to represent and project future CVD mortality and morbidity in the population 35 years-old and older. The objective of this study was to update Argentina’s version of the CVDPM. For this purpose, information from the 2010 National Census, the 2013 National Risk Factor Survey, CESCAS I study, and PrEViSTA study were used to update the dynamics of population size, demographics, and CVD risk factor distributions over time. Model projections were later calibrated by comparing them to actual data on CVD events and mortality in the year 2010 (baseline year) in Argentina. Country statistics for people 35 years-old and older reported for 2010 a total of 41 219 myocardial infarctions (MIs), 58 658 strokes, and 281 710 total deaths. The CVDPM, in turn, predicted 41 265 MIs (difference: 0.11%), 58 584 strokes (difference: 0.13%), and 280 707 total deaths (difference: 0.36%) in the same population. In all cases, the final version of the model predicted the actual number of events with an accuracy superior to 99.5%, and could be used to forecast the changes in CVD incidence and mortality after the implementation of public policies.


La enfermedad cardiovascular (ECV) es la principal causa de muerte en Argentina. Los modelos de simulació;n por computadora permiten extrapolar evidencia a poblaciones más amplias que las originalmente estudiadas, a lo largo de períodos prolongados, y comparar diferentes subpoblaciones. El Cardiovascular Disease Policy Model (CVDPM, por sus siglas en ingló;©s) es un modelo de simulació;n utilizado para representar y proyectar la mortalidad y morbilidad por ECV en la població;n de 35 o más aó;±os. El objetivo de este trabajo fue actualizar la versió;n argentina del CVDPM. Para esto, se utilizó; informació;n del Censo Nacional 2010, la Encuesta Nacional de Factores de Riesgo 2013, el estudio CESCAS I, y el estudio PrEViSTA, para actualizar la dinámica del tamaó;±o de la població;n, sus características demográficas, y la distribució;n de factores de riesgo cardiovasculares a lo largo del tiempo. Las proyecciones del modelo se calibraron comparándolas con informació;n sobre eventos de ECV y mortalidad en el aó;±o 2010 (aó;±o de referencia) en Argentina. Las estadísticas argentinas informaron que en 2010 la població;n de 35 o más aó;±os sufrió; un total de 41 219 infartos de miocardio (IM), 58 658 accidentes cerebrovasculares y 281 710 muertes totales. El CVDPM predijo 41 265 IM (diferencia: 0.11%), 58 584 accidentes cerebrovasculares (diferencia: 0.13%) y 280 707 muertes totales (diferencia: 0.36%). En todos los casos, la versió;n final del modelo predijo el nó;ºmero real de eventos cardiovasculares con una precisió;n superior al 99.5%, pudiendo ser utilizado para pronosticar cambios en la incidencia y mortalidad de ECV debidos de la implementació;n de políticas pó;ºblicas.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Computer Simulation , Cardiovascular Diseases/mortality , Mortality/trends , Risk Assessment/methods , Argentina/epidemiology , Time Factors , Calibration , Sex Factors , Incidence , Reproducibility of Results , Risk Factors , Age Factors , Sex Distribution , Age Distribution , Forecasting
20.
Medicina (B.Aires) ; 79(6): 438-444, dic. 2019. ilus, graf, tab
Article in Spanish | LILACS | ID: biblio-1056750

ABSTRACT

La enfermedad cardiovascular (ECV) es la principal causa de muerte en Argentina. Los modelos de simulació;n por computadora permiten extrapolar evidencia a poblaciones más amplias que las originalmente estudiadas, a lo largo de períodos prolongados, y comparar diferentes subpoblaciones. El Cardiovascular Disease Policy Model (CVDPM, por sus siglas en ingló;©s) es un modelo de simulació;n utilizado para representar y proyectar la mortalidad y morbilidad por ECV en la població;n de 35 o más aó;±os. El objetivo de este trabajo fue actualizar la versió;n argentina del CVDPM. Para esto, se utilizó; informació;n del Censo Nacional 2010, la Encuesta Nacional de Factores de Riesgo 2013, el estudio CESCAS I, y el estudio PrEViSTA, para actualizar la dinámica del tamaó;±o de la població;n, sus características demográficas, y la distribució;n de factores de riesgo cardiovasculares a lo largo del tiempo. Las proyecciones del modelo se calibraron comparándolas con informació;n sobre eventos de ECV y mortalidad en el aó;±o 2010 (aó;±o de referencia) en Argentina. Las estadísticas argentinas informaron que en 2010 la població;n de 35 o más aó;±os sufrió; un total de 41 219 infartos de miocardio (IM), 58 658 accidentes cerebrovasculares y 281 710 muertes totales. El CVDPM predijo 41 265 IM (diferencia: 0.11%), 58 584 accidentes cerebrovasculares (diferencia: 0.13%) y 280 707 muertes totales (diferencia: 0.36%). En todos los casos, la versió;n final del modelo predijo el nó;ºmero real de eventos cardiovasculares con una precisió;n superior al 99.5%, pudiendo ser utilizado para pronosticar cambios en la incidencia y mortalidad de ECV debidos de la implementació;n de políticas pó;ºblicas.


Cardiovascular disease (CVD) is the leading cause of death in Argentina. Computer simulation models allow to extrapolate evidence to broader populations than the originally studied, over longer timeframes, and to compare different subpopulations. The Cardiovascular Disease Policy Model (CVDPM) is a computer simulation state transition model used to represent and project future CVD mortality and morbidity in the population 35 years-old and older. The objective of this study was to update Argentina’s version of the CVDPM. For this purpose, information from the 2010 National Census, the 2013 National Risk Factor Survey, CESCAS I study, and PrEViSTA study were used to update the dynamics of population size, demographics, and CVD risk factor distributions over time. Model projections were later calibrated by comparing them to actual data on CVD events and mortality in the year 2010 (baseline year) in Argentina. Country statistics for people 35 years-old and older reported for 2010 a total of 41 219 myocardial infarctions (MIs), 58 658 strokes, and 281 710 total deaths. The CVDPM, in turn, predicted 41 265 MIs (difference: 0.11%), 58 584 strokes (difference: 0.13%), and 280 707 total deaths (difference: 0.36%) in the same population. In all cases, the final version of the model predicted the actual number of events with an accuracy superior to 99.5%, and could be used to forecast the changes in CVD incidence and mortality after the implementation of public policies.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Computer Simulation , Cardiovascular Diseases/mortality , Mortality/trends , Risk Assessment/methods , Argentina/epidemiology , Time Factors , Calibration , Sex Factors , Incidence , Reproducibility of Results , Risk Factors , Age Factors , Sex Distribution , Age Distribution , Forecasting
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