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1.
Alerta (San Salvador) ; 5(1): 50-56, ene. 28, 2022.
Article in Spanish | LILACS, BISSAL | ID: biblio-1354461

ABSTRACT

Las tecnologías de información y comunicación suponen un avance para la sociedad. Hoy en día, los dispositivos móviles proveen servicios convenientes para la cotidianidad, facilitando la comunicación, el ocio y las relaciones interpersonales, sin embargo, se describe que su uso excesivo influye en la aparición de síntomas como ansiedad, comportamientos adictivos y alteraciones del sueño. De todos los usuarios de estas tecnologías, los adolescentes son un grupo especialmente afectado, debido al fácil acceso a estas desde edades muy tempranas y la consecuente integración a su vida diaria. Por lo que se pretende determinar el papel del uso de dispositivos móviles en el desarrollo de trastornos del sueño en adolescentes. Pese a sus efectos deletéreos, se ha observado que el uso de estas tecnologías puede ocasionar sensación de bienestar y apoyo social en algunos usuarios, particularmente cuando promueve la interacción con sus pares. El uso excesivo de las tecnologías, en especial horas antes de dormir, se relaciona con un patrón de sueño anómalo, se ha identificado que los trastornos del sueño más prevalentes en los usuarios son el insomnio y la somnolencia diurna excesiva


Information and communication technologies represent an advance for society. Nowadays, mobile devices provide convenient services for everyday life, facilitating communication, leisure and interpersonal relationships, however, it is described that their excessive use influences the appearance of symptoms such as anxiety, addictive behaviors and sleep disturbances. Of all the users of these technologies, adolescents are a particularly affected group, due to the easy access to them from a very early age and the consequent integration into their daily lives. Therefore, it is intended to determine the role of the use of mobile devices in the development of sleep disorders in adolescents. Despite their deleterious effects, it has been observed that the use of these technologies can cause a feeling of well-being and social support in some users, particularly when it promotes interaction with their peers. The excessive use of technologies, especially hours before bed, is related to an abnormal sleep pattern, it has been identified that the most prevalent sleep disorders in users are insomnia and excessive daytime sleepiness


Subject(s)
Sleep Wake Disorders , Technology , Adolescent , Behavior, Addictive , Disorders of Excessive Somnolence , Sleep Initiation and Maintenance Disorders , Anxiety , Sleep , Computers, Handheld
2.
Rev. Méd. Inst. Mex. Seguro Soc ; 59(6): 551-559, 01-dic-2021. ilus, tab, graf
Article in Spanish | LILACS | ID: biblio-1357567

ABSTRACT

Introducción: el buen sueño es esencial para la salud física y mental a lo largo de la vida. Sin embargo, existen pocos reportes sobre los problemas del sueño que enferentan las personas mayores que viven en la comunidad. Objetivo: describir la prevalencia de los principales problemas de sueño y su relación con condiciones médicas en las personas mayores que viven en la comunidad. Material y métodos: estudio transversal descriptivo con 1678 personas de 60 años y más, derechohabientes del Instituto Mexicano del Seguro Social (IMSS) en la Ciudad de México. Se evaluó la duración del sueño, la calidad del sueño, la somnolencia diurna, el insomnio y el riesgo de apnea obstructiva de sueño, junto con algunas variables sociodemográficas y condiciones médicas. Resultados: las personas mayores reportaron dormir, en promedio, 6.04 (± 1.5) horas por noche; el 49.1% tenía baja calidad del sueño y el 19.1% experimentaba somnolencia diurna; el 30.8% presentó insomnio y el 27.5% tenía riesgo de apnea obstructiva del sueño. Se observó un patrón de mayor prevalencia de problemas de sueño en las personas mayores con depresión, deterioro cognitivo, dificultades para realizar actividades básicas de la vida diaria y en quienes consumían medicamentos para el sistema nervioso. Conclusiones: este estudio mostró que las personas mayores duermen pocas horas, tienen baja calidad de sueño y prevalencia alta de trastornos del sueño. La identificación y el tratamiento de los problemas del sueño en las personas mayores debe ser una prioridad en el IMSS.


Background: Good sleep is essential for physical and mental health throughout life. However, there are few reports describing the sleep problems experienced by community-dwelling older people. Objective: To describe the prevalence of sleep disorders and their relationship with medical conditions in community-dwelling older people. Methods: Cross-sectional study with 1678 older people (60 years and over) from the Mexican Institute of Social Security (IMSS) in Mexico City. Sleep duration, sleep quality, daytime sleepiness, insomnia and risk of obstructive sleep apnea were evaluated, alongside with sociodemographic variables and medical conditions. Results: Participants self-reported an average sleep duration of 6.04 (± 1.5) hours per night, approximately half had poor sleep quality (49.1%), and 2 out of 10 experienced daytime sleepiness (19.1%); one third had insomnia (30.8%) and risk of obstructive sleep apnea (27.5%). A pattern of higher prevalence of sleep problems was observed in older adults with depression, with cognitive impairment, with difficulties in basic activities of daily living and in those taking medications for the nervous system. Conclusions: This study showed that older people sleep few hours, have low sleep quality, and have a high prevalence of sleep disorders. The identification and treatment of sleep disordes in older people should be a priority in the IMSS.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Aged, 80 and over , Mental Health , Cross-Sectional Studies , Sleep Apnea, Obstructive , Geriatrics , Mexico , Sleep Wake Disorders , Aging , Disorders of Excessive Somnolence , Sleep Initiation and Maintenance Disorders , Nervous System
3.
Rev. bras. neurol ; 57(4): 31-39, out.-dez. 2021. tab, ilus
Article in English | LILACS-Express | LILACS | ID: biblio-1359225

ABSTRACT

There is a known relationship between seizures and sleep deprivation that increases epileptiform abnormalities and slow waves expressed in the EEG, but chronic insomnia, greater in patients with epilepsy (PWEs) than in healthy control, supposedly has a different mechanism linked to a hyperarousability state with increased rapid EEG activity and associated "restless REM". Therefore, there is a complex interaction at various levels between insomnia and epilepsy that may play a role in seizure presentation. The recognized interconnection between mood and anxiety disorders and insomnia should also advise special care in the management of psychiatric comorbidities in PWEs. This article raises questions related to the interaction between the brain basis of insomnia and epilepsy and the triggers of seizures, particularly sleep deprivation.


Há uma relação conhecida entre crises epilépticas e privação de sono que aumenta as anormalidades epileptiformes e as ondas lentas expressas no EEG, mas a insônia crônica, maior em pacientes com epilepsia (PCE) do que no controle saudável, supostamente tem um mecanismo diferente ligado a um estado de hiperexcitabilidade com aumento da atividade rápida do EEG e associado "REM inquieto". Consequentemente, existe uma complexa interação em vários níveis entre a insônia e a epilepsia que pode desempenhar um papel na apresentação das crises. A reconhecida interligação entre transtornos de humor e ansiedade com a insônia também deve aconselhar um cuidado especial no manejo das comorbidades psiquiátricas do PCE. Este artigo levanta questões relacionadas à interação entre a base cerebral da insônia e da epilepsia e os desencadeadores de crises epilépticas, principalmente a privação do sono.


Subject(s)
Humans , Adult , Sleep Deprivation , Epilepsy/complications , Epilepsy/diagnosis , Sleep Initiation and Maintenance Disorders/physiopathology , Sleep Initiation and Maintenance Disorders/epidemiology , Seizures/etiology , Sleep Wake Disorders , Prevalence , Risk Factors , Sleep Initiation and Maintenance Disorders/etiology , Mental Disorders
4.
SMAD, Rev. eletrônica saúde mental alcool drog ; 17(4): 74-82, out.-dez. 2021. ilus, tab
Article in Portuguese | LILACS, INDEXPSI | ID: biblio-1347843

ABSTRACT

OBJETIVO: o objetivo deste estudo foi investigar possíveis associações entre Burnout, uso de hipnóticos e qualidade do sono em estudantes de medicina. MÉTODO: foi realizado um estudo transversal quantitativo com estudantes de medicina de um centro universitário do nordeste do Brasil, com metodologia de Aprendizagem Baseada em Problemas (ABP). O Maslach Burnout Inventory-Student Survey, o Pittsburgh Sleep Quality Index (PSQI) e um questionário sociodemográfico foram aplicados entre os alunos do pré-internato do curso. RESULTADOS: o estudo incluiu 523 alunos e encontrou 48 (9,2%) com critérios de diagnóstico tridimensional para Síndrome de Burnout (SB). A má qualidade do sono e o uso de hipnóticos para dormir foram associados à SB (p < 0,001 e p = 0,003, respectivamente). Não houve diferenças estatísticas quanto à idade, sexo, religião, estado civil, financiamento escolar e realização de trabalho remunerado, entre indivíduos com e sem SB. CONCLUSÃO: houve associação entre SB, uso de hipnóticos e má qualidade do sono em estudantes de medicina pré-internato.


OBJECTIVE: the aim of this study was to investigate possible associations between Burnout, use of hypnotics and sleep quality among medical students. METHOD: a cross-sectional quantitative study was conducted among medical students of a university center of northeastern Brazil, with the problem-based learning (PBL) methodology. The Maslach Burnout Inventory-Student Survey, the Pittsburgh Sleep Quality Index (PSQI) and a sociodemographic questionnaire were applied among pre-clerkship students of the course. RESULTS: the study included 523 students and found 48 (9.2%) with tridimensional diagnosis criteria for Burnout syndrome (BS). Poor sleep quality and use of hypnotic drugs for sleep were associated with BS (p < 0.001 and p = 0.003, respectively). There were no statistical differences in age, gender, religion, marital status, student financing and performing paid work, between individuals with and without BS. CONCLUSION: there was an association between BS, use of hypnotics and poor sleep quality among pre-clerkship medical students.


OBJETIVO: el objetivo de este estudio fue investigar las posibles asociaciones entre el síndrome de Burnout, el uso de hipnóticos y la calidad del sueño entre estudiantes de medicina. MÉTODOS: se realizó un estudio cuantitativo transversal entre estudiantes de medicina de un centro universitario del noreste de Brasil, con metodología de aprendizaje basado en problemas (ABP). Se aplicó el Maslach Burnout Inventory-Student Survey, el Pittsburgh Sleep Quality Index (PSQI) y un cuestionario sociodemográfico entre los estudiantes de pre-administrativo del curso. RESULTADOS: el estudio incluyó a 523 estudiantes y encontró 48 (9,2%) con criterios de diagnóstico tridimensional de síndrome de Burnout (SB). La mala calidad del sueño y el uso de fármacos hipnóticos para dormir se asociaron con SB (p <0,001 y p = 0,003, respectivamente). No hubo diferencias estadísticas en edad, sexo, religión, estado civil, financiamiento de los estudiantes y realización de trabajo remunerado, entre individuos con y sin SB. CONCLUSIÓN: hubo asociación entre SB, uso de hipnóticos y mala calidad del sueño entre los estudiantes de medicina antes de la rotación clínica.


Subject(s)
Humans , Male , Female , Education, Medical , Education, Medical, Undergraduate , Sleep Aids, Pharmaceutical , Burnout, Psychological , Sleep Initiation and Maintenance Disorders
5.
Rev. enferm. Inst. Mex. Seguro Soc ; 29(3): 174-180, 04-oct-2021. graf, tab
Article in Spanish | LILACS, BDENF | ID: biblio-1357966

ABSTRACT

Introducción: los pacientes con enfermedad renal crónica (ERC), y en específico los que tienen tratamiento renal sustitutivo (TRS), se ven afectados en su ciclo circadiano y en su calidad del sueño. Objetivo: evaluar la calidad del sueño de los pacientes con enfermedad renal crónica que acuden al servicio de Nefrología de una unidad médica de segundo nivel de atención. Metodología: estudio comparativo en pacientes con ERC del servicio de Nefrología, clasificados en tres grupos, dos de ellos en terapia de reemplazo renal (diálisis peritoneal y hemodiálisis) y uno sin terapia de reemplazo renal (prediálisis). Para la calidad del sueño se utilizó la escala de Pittsburgh, se incluyeron datos sociodemográficos y parámetros bioquímicos. Los datos se analizaron median- te comparación de frecuencias con Chi cuadrada, medias con t de Student y ANOVA de un factor. Resultados: se formaron tres grupos: hemodiálisis (n = 75), diálisis peritoneal (n = 58) y prediálisis (n = 71). La edad media fue de 53.5 años; la calidad subjetiva del sueño fue buena en el 48% del total y en el 54.9% de los pacientes en prediálisis (p < 0.05). Al aplicar la escala de Pittsburgh, el 80.4% del total y el 84.5% de los pacientes en diálisis reportaron una calidad de sueño mala. De las siete dimensiones evaluadas, dos fueron diferentes en los tres grupos (p < 0.05). Conclusiones: la percepción del paciente sobre la calidad del sueño habitualmente se sobreestima, lo que indica una adaptación a un sueño ineficiente. Debido a las características de estos pacientes es importante mantener un control de sus parámetros bioquímicos, que también tienen un impacto en la calidad del sueño.


Introduction: In patients with chronic kidney disease (CKD) and specifically with renal replacement therapy (RRT), their circadian cycle and consequently their sleep quality are affected. Objective: To evaluate the quality of sleep in patients with chronic kidney disease attends at the nephrology service. Methods: Comparative study in patients with chronic kidney disease from the nephrology service classified into three groups, two of them had renal replacement therapy (peritoneal dialysis and hemodialysis) and one without renal replacement therapy (predialysis). For the quality of sleep we used the Pittsburgh Scale, sociodemographic data and biochemical parameters were included. Comparison of frequencies with chi-square, means with Student's t and Anova of one factor. Results: Three groups were formed: hemodialysis (n = 75), peritoneal dialysis (n = 58) and predialysis (n = 71). The mean age was 53.5 years; the subjective quality of sleep was "good" in 48.0% of the total and in 54.9% of predialysis patients (p <0.05). When applying the Pittsburgh scale, 80.4% of the total and 84.5 of the dialysis patients reported a "poor" quality of sleep. Of the seven dimensions evaluated, two were different in the three groups (p < 0.05) Conclusions: The patient's perception of the quality of sleep is regularly overestimated, which indicates an adaptation to this dream habit. Due to the characteristics of these patients, it is important to keep a check on their biochemical parameters, which also have an impact on the quality of sleep.


Subject(s)
Humans , Secondary Care , Renal Insufficiency, Chronic , Sleep Initiation and Maintenance Disorders , Peritoneal Dialysis , Mexico , Nephrology
6.
Arq. bras. cardiol ; 117(3): 446-454, Sept. 2021. tab
Article in English, Portuguese | LILACS | ID: biblio-1339176

ABSTRACT

Resumo Fundamento A íntima relação entre a regulação do sono e os eventos cardiovasculares é um dos principais focos de investigação na medicina contemporânea. Hábitos e características do sono interferem na ritmicidade cardíaca e também na expectativa de vida, principalmente em idosos. Objetivo Estimar o risco de óbito e de eventos cardiovasculares em idosos comunitários que apresentam queixa de insônia e sonolência excessiva diurna ao longo de oito anos de seguimento. Método Foi desenhada uma coorte prospectiva com 160 idosos, a primeira onda em 2009 e a segunda em 2017. Os grupos de seguimento foram determinados pela exposição ou não às queixas de insônia primária e a sonolência excessiva diurna, com ou sem ronco. As covariáveis sexo, estado conjugal, depressão, hipertensão e diabetes foram controladas. O desfecho primário foi o óbito e o secundário, os eventos cardiocerebrovasculares (ECV). As probabilidades dos desfechos foram estimadas pelo risco relativo (RR), através da regressão de Poisson, adotando-se α ≤ 0,05. Resultados Registraram-se 40 mortes no período (25,97%:19,04-32,89) e 48 ECVs (30,76%:23,52-38,01). Os homens apresentaram maior risco (RR = 1,88;1,01-3,50) de óbito. A depressão (RR = 2,04;1,06-3,89), a gravidade da insônia (RR = 2,39;1,52-4,56) e a latência do sono entre 16-30 minutos (RR = 3,54;1,26-9,94) e 31-60 minutos (RR = 2,23;1,12-4,47) aumentaram independentemente o risco de óbito em idosos comunitários. Os ECVs foram preditos apenas por idosos hipertensos e/ou diabéticos (RR = 8,30; 1,98-34,82). Conclusão A mortalidade em idosos é influenciada pelo estado emocional e pela dificuldade de dormir, diferentemente dos ECVs, condicionados apenas pelas condições pressóricas arteriais e metabólicas.


Abstract Background The close relationship between sleep regulation and cardiovascular events is one of the main focuses of research in contemporary medicine. Sleep habits and characteristics interfere with the cardiac rhythm and also with life expectancy, especially in the elderly. Objective To estimate the risk of death and cardiovascular events in community-dwelling elderly individuals complaining of insomnia and excessive daytime sleepiness over eight years of follow-up. Method A prospective cohort was designed with 160 elderly, with the first wave occurring in 2009 and the second in 2017. Follow-up groups were determined by exposure or not to complaints of primary insomnia and excessive daytime sleepiness with or without snoring. The covariates gender, marital status, depression, hypertension and diabetes were controlled. The primary outcome was death and the secondary outcome was cardio-cerebrovascular events (CCV). Outcome risks were estimated by relative risk (RR) through Poisson regression, adopting α≤0.05. Results There were 40 (25.97%: 19.04-32.89) deaths over the period and 48 (30.76%: 23.52-38.01) CCV. Men had a higher risk (RR = 1.88; 1.01-3.50) of death. Depression (RR = 2.04; 1.06-3.89), insomnia severity (RR = 2.39; 1.52-4.56) and sleep latency between 16-30 minutes (RR = 3, 54; 1.26-9.94) and 31-60 minutes (RR = 2.23; 1.12-4.47) increased the risk of death independently in community-dwelling elderly. CCV were predicted only in the hypertensive and / or diabetic elderly (RR = 8.30; 1.98-34.82). Conclusion Mortality in the elderly is influenced by the emotional state and difficulty in falling asleep, unlike CCVs, which are conditioned only by arterial and metabolic blood pressure conditions.


Subject(s)
Humans , Male , Aged , Disorders of Excessive Somnolence/epidemiology , Sleep Initiation and Maintenance Disorders , Urban Population , Brazil/epidemiology , Prospective Studies , Cohort Studies , Depression/epidemiology
7.
Gac. méd. Méx ; 157(3): 228-233, may.-jun. 2021. tab, graf
Article in Spanish | LILACS | ID: biblio-1346101

ABSTRACT

Resumen Introducción: La pandemia de COVID-19 también ha afectado la salud mental. Objetivo: Evaluar la salud mental de la población mexicana durante la pandemia de COVID-19 mediante la medición de síntomas de estrés, depresión, ansiedad, insomnio y resiliencia. Métodos: Estudio observacional, descriptivo y transversal. Con una encuesta se recabaron datos sociodemográficos y se aplicaron la Depression Anxiety and Stress Scale 21 (DASS 21), la Escala Atenas de Insomnio y la Escala de Resiliencia 14 Ítems (RS-14). Se obtuvieron medidas de tendencia central y de dispersión en las variables cuantitativas, así como frecuencias en las cualitativas. En el análisis bivariado se utilizó la prueba de χ2; el nivel alpha fue 0.05. Resultados: Se analizaron 1667 individuos con edad media de 33.78 ± 10.79 años. En la DASS 21 se encontró una media de 9.7 puntos (normal), 7.10 para ansiedad (normal) y 6.73 para depresión (normal). La Escala Atenas de Insomnio presentó una media de 9.33 puntos (alteración moderada) y la RS-14, 69.13 (resiliencia alta). Conclusiones: La intensidad de la sintomatología fue menor a la esperada en comparación con la registrada en otras poblaciones, probablemente por la alta resiliencia de la población mexicana.


Abstract Introduction: The COVID-19 pandemic has also affected mental health. Objective: To evaluate Mexican population mental health during the COVID-19 pandemic by measuring symptoms of stress, depression, anxiety and insomnia, as well as resilience. Methods: Cross-sectional, descriptive, observational study. A survey was carried out to collect sociodemographic data, and the Depression Anxiety and Stress Scale 21 (DASS 21), Athens Insomnia Scale and the 14-item Resilience Scale (RS-14) were applied. Central tendency and dispersion measures were obtained for quantitative variables and frequencies for qualitative variables. The chi-square test was used for bivariate analysis; alpha level was 0.05. Results: 1,667 individuals with a mean age of 33.78 ± 10.79 years were analyzed. On DASS 21, a mean of 9.7 points (normal) was found, as well as 7.10 for anxiety (normal) and 6.73 for depression (normal). In the Athens Insomnia Scale, a mean of 9.33 points (moderate alteration), and in the RS-14 scale, 69.13 points (high resilience) were obtained. Conclusions: Symptoms' intensity was lower than expected in comparison with that recorded in other populations, probably due to the high levels of resilience of the Mexican population.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Young Adult , Mental Health , Resilience, Psychological , COVID-19/psychology , Anxiety/epidemiology , Psychiatric Status Rating Scales , Stress, Psychological/epidemiology , Cross-Sectional Studies , Surveys and Questionnaires , Depression/epidemiology , Sleep Initiation and Maintenance Disorders/epidemiology , Mexico/epidemiology
8.
Fortaleza; s.n; mar. 2021.
Thesis in Portuguese | LILACS, BDENF | ID: biblio-1252509

ABSTRACT

Pessoas Vivendo com HIV (PVHIV) são particularmente vulneráveis à má qualidade do sono, devido à múltiplos fatores, como a própria doença, estigma e eventos adversos da Terapia Antirretroviral (TARV). O objetivo geral do estudo foi determinar a prevalência de distúrbios do sono em PVHIV e seu impacto na qualidade de vida. Trata-se de um estudo transversal, realizado no ambulatório de infectologia do Hospital São José (HSJ) em Fortaleza, Ceará. Foi calculada amostra de 385 PVHIV, selecionadas pela estratégia do tipo não probabilística por conveniência, sendo convidados a participar do estudo no dia da consulta de rotina. Os critérios de inclusão foram: PVHIV do sexo masculino ou feminino, idade igual ou maior a 18 anos, em TARV por pelo menos três meses. Critérios de exclusão: gestantes, doença mental incapacitante, moradores de rua e privados de liberdade. A coleta de dados ocorreu no período de um ano, por meio de entrevista em consultório privativo, com duração média de 20 minutos, utilizando os instrumentos: 1. Formulário Sociodemográfico, Epidemiológico e Clínico para PVHIV; 2. Índice de Qualidade do Sono de Pittsburgh (PSQI-BR); e 3. Instrumento de Avaliação da Qualidade de Vida para PVHIV (WHOQOL-HIV-Bref). Para análise de dados realizou-se estatística descritiva, análise de regressão logística univariada e multivariada, para determinar a razão de chances (RC) ajustada, precisão (intervalo de confiança de 95% - IC95%) e significância da estimativa (teste de Wald). Empregaram-se testes bicaudais, estabelecendo se o nível de significância em 0,05 (5%), considerando-se estatisticamente significante o valor P<0,05. O software IBM SPSS Statistics versão 23.0 e o software R versão 4.0.3 foram utilizados para procedimentos estatísticos. O projeto foi aprovado pelos Comitês de Ética em Pesquisa da Universidade Federal do Ceará e HSJ, respeitando-se a Resolução n°466/2012 do Conselho Nacional de Saúde. Os resultados mostraram que a prevalência de distúrbios do sono na amostra foi de 43,38% (intervalo de confiança de 95%: 38,43% - 48,33%). Na análise multivariada, apenas o fato de ter filhos (P=0,0054; RC=1,91; IC95%=1,21-3,01), possuir oito anos ou menos de estudo (P=0,0013; RC=2,11; IC95%=1,34-3,34) e não praticar exercício físico regular (P=0,0001; RC=2,61; IC95%=1,61-4,23), constituíram fatores independentes associados à ocorrência de distúrbios do sono em PVHIV. Quando avaliada a percepção geral das pessoas com HIV acerca da qualidade de vida pelo instrumento WHOQOL-HIV-Bref (pergunta 1), categorizando-se em satisfatória (respostas: 4-boa, 5-muito boa) e insatisfatória (respostas: 1-muito ruim, 2-ruim, 3-nem ruim nem boa), teve-se uma prevalência de 34,80% de qualidade de vida insatisfatória. Na análise de regressão logística multivariada, a renda mensal menor ou igual a um salário mínimo (P<0,0001; RC=3,19; IC95%=1,87-5,45), não praticar exercício físico regular (P=0,0032; RC=2,27; IC95%=1,32-3,92), ter distúrbios do sono (P=0,0039; RC=2,04; IC95%=1,26-3,31) e estar desempregado, constituíram fatores independentes associados à qualidade de vida insatisfatória. Quanto à mediana dos escores do instrumento WHOQOL-HIV-Bref, a percepção da qualidade de vida nos Domínios II (Psicológico), III (Nível de Independência) e V (Meio Ambiente) foi considerada intermediária, e superior nos Domínios I (Físico), Domínio IV (Relações Sociais) e Domínio VI (Espiritualidade/Religião/Crenças). Concluiu-se que 43,38% das PVHIV da amostra tinham distúrbios do sono, sobretudo, aqueles com filhos, oito anos ou menos de estudo e que não praticavam exercício físico regular. Na análise da qualidade de vida, 34,80% das PVHIV tiveram percepção insatisfatória, principalmente, aquelas com renda mensal menor ou igual a um salário mínimo, desempregados, sem prática regular de exercício físico e com distúrbios do sono. Os domínios do instrumento WHOQOL-HIV-Bref mais afetados foram o II, III e V, nos quais a percepção acerca da qualidade de vida foi considerada intermediária. (AU)


Subject(s)
Quality of Life , Acquired Immunodeficiency Syndrome , HIV , Health Promotion , Sleep Initiation and Maintenance Disorders
10.
Article in English | AIM, AIM | ID: biblio-1292754

ABSTRACT

Objectives: The COVID-19 pandemic has created significant psychological challenges globally. Evidence has been mounting of greater emotional distress and possible worsening of underlying psychiatric disorders, due to repercussions of COVID-19. In addition, the pandemic has created barriers to access for help, due to social distancing and travel restrictions. Thus, creating a major need for effective interventions that can be accessed safely from home and provide coping tools which can be learned and practiced while in isolation. An App based Yoga of Immortals (YOI) program is one such strategy to help cope with stressful situations. The objective of this study was to investigate if the YOI program can provide significant benefit for depressive and insomnia symptoms. Material and Methods: Participants in this study were asked to complete two brief online but well validated mental health screening tools before intervention. This was followed by a 7-week long YOI intervention. Following the intervention, participants were once again asked to complete the online validated questionnaires. The survey questionnaires included baseline demographic data and validated scales for measuring insomnia severity Insomnia severity Index (ISI) and levels of depression symptoms patient health questionnaire-8, (PHQ-8). All statistical analysis was performed using the Statistical Package for the Social Science. Results: SY YOI intervention of 7 weeks significantly improved the ISI scores as well as PHQ-8 scores in the study population (P < 0.0001 in all comparisons). Conclusion: YOI intervention is an effective intervention strategy for decreasing insomnia and depression symptoms, even during the pandemic


Subject(s)
Humans , Meditation , Depression , Mindfulness , COVID-19 , Sleep Initiation and Maintenance Disorders , Mental Disorders
11.
Article in Chinese | WPRIM | ID: wpr-921687

ABSTRACT

To evaluate the efficacy and safety of Chinese patent medicines in the treatment of insomnia by frequency network Meta-analysis. Randomized controlled trials of Chinese patent medicines for insomnia were retrieved from CNKI, Wanfang, VIP, SinoMed, PubMed, EMbase and Cochrane Library databases from the time of database establishment to October 2020. The quality of the included RCTs was evaluated according to the Cochrane bias risk standard, and the data was analyzed by RevMan 5.3 and Stata/MP 15.1. A total of 11 kinds of Chinese patent medicines in 27 RCTs were included. According to Meta-analysis, in term of the effective rate, Tianmeng Liquid, Zaoren Anshen Capsules, Shumian Capsules, Shensong Yangxin Capsules, Shenqi Wuweizi Tablets, Shugan Jieyu Capsules, Anshen Bunao Liquid and Qiye Anshen Tablets combined with nonbenzodiazepine drugs(NBZDs) were superior to NBZDs alone. In term of the improvement of Pittsburg sleeping quality index(PSQI) score, Tianmeng Liquid, Shumian Capsules, Shensong Yangxin Capsules, Bailemian Capsules, Shenqi Wuweizi Tablets, Shugan Jieyu Capsules, Yangxue Qingnao Granules and Yindan Xinnaotong Capsules combined with NBZDs were superior to NBZDs alone. In terms of the safety, Shumian Capsules, Shensong Yangxin Capsules, Shenqi Wuweizi Tablets and Qiye Anshen Tablets combined with NBZDs were superior to NBZDs alone. In terms of the avoidance of dizziness and headache, Qiye Anshen Tablets combined with NBZDs were superior to NBZDs alone. The results of Network Meta-analysis indicated that in term of the effective rate, top three optimal medication regimens were NBZDs combined with Shugan Jieyu Capsules, combined with Zaoren Anshen Capsules and combined with Shensong Yangxin Capsules in the order from high to low. With the respect of improvement of PSQI score, top three optimal medication regimens were NBZDs combined with Yangxue Qingnao Granules, combined with Tianmeng Liquid and combined with Yindan Xinnaotong Capsules in the order from high to low. In terms of the safety, top three optimal medication regimens were NBZDs combined with Qiye Anshen Tablets, combined with Shensong Yangxin Capsules and combined with Shenqi Wuweizi Tablets in the order from high to low. In terms of the avoidance of dizziness and headache, top three optimal medication regimens were NBZDs combined with Qiye Anshen Tablets, combined with Zaoren Anshen Capsules and combined with Shumian Capsules in the order from high to low. In terms of the avoidance of fatigue, top three optimal medication regimens were NBZDs combined with Shensong Yangxin Capsules, combined with Shumian Capsules and combined with Qiye Anshen Tablets in the order from high to low. In conclusion, Chinese patent medicines combined with NBZDs can effectively alleviate the symptoms of insomnia with a high safety. However, the conclusion of this study needs to be verified by more high-quality studies because of the low methodological quality of the included studies.


Subject(s)
China , Drugs, Chinese Herbal , Humans , Medicine, East Asian Traditional , Network Meta-Analysis , Nonprescription Drugs , Sleep Initiation and Maintenance Disorders/drug therapy
12.
Article in Chinese | WPRIM | ID: wpr-921563

ABSTRACT

Insomnia is a subjective experience of difficulty in falling asleep and/or maintaining sleep accompanied by the impairment of daytime social functioning due to insufficient sleep quality or quantity to meet normal physiological needs.It has chronic damage to all the human body systems and is the most common sleep disorder.The main mechanism for the occurrence and maintenance of insomnia is the hyperarousal hypothesis,and microarousal,as a cortical arousal,is also involved in the formation of the hyperarousal mechanism.The mechanism and clinical significance of microarousal were reviewed and summarized in this paper in order to guide the clinical work.


Subject(s)
Arousal , Humans , Sleep , Sleep Initiation and Maintenance Disorders
13.
Chinese Acupuncture & Moxibustion ; (12): 1405-1408, 2021.
Article in Chinese | WPRIM | ID: wpr-921066

ABSTRACT

The published literature of insomnia in the elderly treated with acupuncture was retrieved in CNKI, Wanfang and VIP from the date of establishment to December 31, 2019. Association rule analysis and cluster analysis were used to summarize the acupoint selection rules of insomnia in the elderly treated with acupuncture. A total of 37 articles were included, involving 60 acupuncture prescriptions. The most commonly used acupoints were Sanyinjiao (SP 6), Shenmen (HT 7), Anmian (Extra), Baihui (GV 20), Sishencong (EX-HN 1), Neiguan (PC 6), Xinshu (BL 15) and Taixi (KI 3). The most commonly used acupoint combinations were Sanyinjiao (SP 6)-Anmian (Extra)-Baihui (GV 20)-Sishencong (EX-HN 1)-Shenting (GV 24)-Shenmen (HT 7)-Xinshu(BL 15), Xinshu(BL 15)-Pishu (BL 20)-Shenshu (BL 23)-Shenting (GV 24), Zhaohai (KI 6)-Shenmai (BL 62), Taichong (LR 3)-Ganshu (BL 18), Daling (PC 7)-Taixi (KI 3), Neiguan (PC 6)- Zusanli (ST 36) and Guanyuan (CV 4)-Qihai (CV 6)-Zhongwan (CV 12). On the basis of acupoint selection according to disease differentiation, the acupoint selection rules and characteristics of insomnia in the elderly treated with acupuncture are regulating and supplementing the spleen and kidney and treating according to spleen-kidney.


Subject(s)
Acupuncture Points , Acupuncture Therapy , Aged , Cell Differentiation , Humans , Publications , Sleep Initiation and Maintenance Disorders/therapy
14.
Article in Chinese | WPRIM | ID: wpr-888156

ABSTRACT

To systematically evaluate the efficacy of oral Chinese patent medicines of Ziziphi Spinosae Semen in the treatment of primary insomnia by using network Meta-analysis. Nine databases(CNKI, Wanfang, VIP, CBM, PubMed, EMbase, Web of Science, Medline and Cochrane Library) were systematically and comprehensively undertaken to identify the literatures published from the establishment of each database to August, 2020. Randomized controlled trials(RCTs) on oral Chinese patent medicine of Ziziphi Spinosae Semen in the treatment of primary insomnia, either alone or in combination with conventional sedative hypnotics, were screened out according to inclusion criteria and exclusion criteria. Literature screening, data extraction and the evaluation of the risk of bias for the included studies were conducted independently by 2 researchers. Traditional Meta-analysis and Bayesian network Meta-analysis were then conducted with use of Stata 15.0 and R software. Finally, a total of 42 RCTs were included, involving 9 kinds of oral Chinese patent medicines and 4 196 patients. The results of Meta-analysis showed that(1) in terms of improving Pittsburgh sleep quality index scale score, the efficacy of the combination of drugs was significantly superior to that of sedative-hypnotics or most of Chinese patent medicines used alone, and Bailemian Capsules combined with sedative-hypnotics had the best effect; both the efficacy of Shenqi Wuweizi Tablets and Compound Zaoren Anshen Capsules alone were significantly superior to that of conventional sedative-hypnotics treatment, and Shenqi Wuweizi Tablets had the best effect.(2)In terms of safety, single use or combined use of Chinese patent medicine had a certain improvement as compared with conventional sedative-hypnotics treatment. Due to the large clinical heterogeneity, the studies could not be combined quantitatively, and no serious adverse reactions occurred in all patients enrolled in the study. The results showed that Chinese patent medicine of Ziziphi Spinosae Semen combined with conventional sedative-hypnotics could significantly improve the short-term sleep quality of patients with primary insomnia. In the comparison among single use of drugs, Shenqi Wuweizi Tablets had the largest possibility for best effect. However, the lack of evidences for international promotion, the influence of different types of sedative-hypnotics treatment and intervention time on the curative effect, and the patients' different acceptance of combined treatment should be considered before clinical application. Limited by the number and quality of the included studies, the above conclusions need to be further verified by more large sample-size and high-quality studies.


Subject(s)
Bayes Theorem , China , Drugs, Chinese Herbal/therapeutic use , Humans , Network Meta-Analysis , Nonprescription Drugs , Semen , Sleep Initiation and Maintenance Disorders/drug therapy
15.
Article in Chinese | WPRIM | ID: wpr-888039

ABSTRACT

The acupoint application of Euodiae Fructus at Yongquan(KI1) can significantly improve the sleep quality of patients with insomnia with berberine as the main effective component for the efficacy. Nineteen active compounds and 203 drug targets were screened out from Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform(TCMSP). After comparison with GeneCards and Online Mendelian Inheritance in Man(OMIM), 24 common genes of diseases and drugs were obtained. STRING 11.0 was used to construct a protein-protein interaction(PPI) network of the overlapping genes, and Matthews correlation coefficient(MCC) was employed to screen the core genes, which were then subjected to enrichment analysis with gene ontology(GO) and Kyoto encyclopedia of genes and genomes(KEGG). The results revealed that the main compounds of Euodiae Fructus, such as berberine and rutaecarpine, participated in the biological processes(such as neurotransmitter receptor activity) by regulating C-reactive protein(CRP), estrogen receptor 1(ESR1), 5-hydroxytryptamine(5-HT) receptor, and interleukin-6(IL-6) to exert sedative, anxiolytic, and antidepressant effects. Sixty 4-week-old SPF mice were randomly divided into a control group, a model group, a positive drug(diazepam tablets) group, and low-, medium-, and high-dose berberine groups. Medication with corresponding drugs was performed for one week. The results demonstrated that berberine was potent in reducing the activities and standing times of mice, down-regulating the levels of CRP and IL-6 mRNA in the hypothalamus, and up-regulating the expression of 5-HT(P<0.01); however, no significant effect on ESR1 was observed. The network of Euodiae Fructus in treating insomnia was constructed by network pharmacology and verified by tests. The findings indicated that the therapeutic efficacy of Euodiae Fructus in treating insomnia was achieved by participating in multiple biological processes, such as neurotransmitter receptor activity, which provided a scientific basis for its clinical application.


Subject(s)
Animals , Databases, Genetic , Drugs, Chinese Herbal/pharmacology , Gene Ontology , Humans , Medicine, Chinese Traditional , Mice , Sleep Initiation and Maintenance Disorders/genetics
16.
Article in Chinese | WPRIM | ID: wpr-888027

ABSTRACT

Huanglian Ejiao Decoction,firstly recorded in Treatise on Febrile Diseases,could be used to treat heat-conversion syndrome of Shaoyin. It has been identified that,the indications of Huanglian Ejiao Decoction include:(1)in modern medicine,it can be used to treat insomnia,arrhythmia,oral ulcer,Xiali,blood syndrome and other diseases;(2)in terms of symptoms and signs,it is mainly used for restlessness,ritability,insomnia,extremely difficult to fall asleep,palpitation,atrial premature beat,ventricular premature beat and other arrhythmias,stomach distension and stuffiness,stomach pain,vomiting,abdominal pain,cramps,lower edge,constipation,blush,red lips,easy bleeding,red tongue,thin or no coating,dry tongue surface,or light red tongue,or dark red,thin white tongue coating,and rapid pulse. It has been also identified that,(1)although the original statement of Huanglian Ejiao Decoction is very simple,it can not only be used according to irritability and insomnia;(2)tongue image is not the key to syndrome differentiation of this prescription;(3)the essence of Shaoyin syndrome is not completely heart kidney Yang deficiency,which is closest to shock in modern medicine,including septic shock,hypovolemic shock and cardiogenic shock;(4)the essential difference between Shaoyin cold and heat conversion syndrome of Shaoyin lies in the different types of shock,in which cardiogenic shock is the main cold type,while septic shock is the main heat shock;(5)heat-conversion syndrome of Shaoyin is more common in the late stage of septic shock,and part of it can be seen in the stage of heart failure combined with sympathetic activation;(6)Dioscoreae Rhizoma and Rehmanniae Radix are often used to replace egg yolk;(7)Huanglian Ejiao Decoction takes effect quickly and the course of treatment is short.


Subject(s)
Drugs, Chinese Herbal/therapeutic use , Gelatin , Humans , Medicine, Chinese Traditional , Sleep Initiation and Maintenance Disorders/drug therapy , Yang Deficiency
17.
Article in Chinese | WPRIM | ID: wpr-887480

ABSTRACT

OBJECTIVE@#To observe the efficacy of @*METHODS@#A total of 58 participants were included. Of them, 29 patients with insomnia were included into an observation group, and 29 healthy participants were included into a control group. The patients in the observation group were treated with @*RESULTS@#The total effective rate was 89.7% (26/29) in the observation group. In the observation group, the scores of PSQI, ISI and DISS, the A, B speed of NCT were all decreased after treatment (@*CONCLUSION@#The


Subject(s)
Acupuncture Therapy , Brain/diagnostic imaging , Emotions , Humans , Magnetic Resonance Imaging , Sleep Initiation and Maintenance Disorders/therapy
18.
Article in Chinese | WPRIM | ID: wpr-879113

ABSTRACT

Based on the research literatures of Passiflora incarnata and the theory of traditional Chinese medicine, the paper discussed the traditional Chinese medicinal properties of P. incarnate, so as to provide a theoretical basis for the compatibility and application of P. incarnata. The literature databases of CNKI, Wanfang, VIP, Web of Science, PubMed and Scopus were selected, and the literatures relating to P. incarnata were reviewed to screen out the scientific research literatures with a high credibility, rational design and reliable conclusions. Foreign pharmacopoeia was consulted, and the listed products were summarized. The traditional Chinese medicine properties of P. incarnata were studied based on 32 clinical trials, 66 pharmacological researches, 64 chemical constituents researches as well as the theory of traditional Chinese medicine. It was preliminarily concluded that the medicinal properties of P. incarnata are sweet, cool, and enter heart, liver channels. The function is mainly to calm the heart and tranquilizing the mind, and calm the liver wind. It is used for hyperactivity of liver-Yang, stagnation of liver-Qi, restlessness of mind, depression, nervousness, insomnia. This paper summarized the source, characteristics of natures, tastes and channel tropism, usage and dosage, function indications of P. incarnata, and defined its clear traditional Chinese medicine property, which lays a theoretical foundation for the compatibility and clinical application of P. incarnata and Chinese medicine.


Subject(s)
Anti-Anxiety Agents , Anxiety , Drugs, Chinese Herbal , Humans , Medicine, Chinese Traditional , Passiflora , Sleep Initiation and Maintenance Disorders/drug therapy
19.
Article in Chinese | WPRIM | ID: wpr-877647

ABSTRACT

OBJECTIVE@#To observe the effect of acupoint application of gel plaster on quality of sleep and life in patients with insomnia.@*METHODS@#A total of 63 patients with insomnia were randomized into a gel plaster group (32 cases, 1 case dropped off) and a placebo plaster group (31 cases). Acupoint application of gel plaster was applied at Yintang (GV 29) and Yongquan (KI 1) in the gel plaster group, placebo plaster was applied at the same acupoints in the placebo plaster group. The treatment was given from bedtime to early moming of the next day, 5 days were as one course, with 2-day interval, totally 4 courses were required in the both groups. Pittsburgh sleep quality index (PSQI), Epworth sleepiness scale (ESS) and Flinders fatigue scale were used to evaluate the sleep quality and fatigue level of the patients in the both groups before and after treatment and at 2 weeks of follow-up. The variations of insomnia TCM syndrome score and the 36-item short-form health survey (SF-36) score before and after treatment were observed.@*RESULTS@#Compared before treatment, the scores of PSQI, ESS and FFS after treatment and at follow-up were decreased in the both groups (@*CONCLUSION@#Acupoint application of gel plaster can effectively improve the quality of sleep and life in patients with insomnia.


Subject(s)
Acupuncture Points , Acupuncture Therapy , Humans , Sleep , Sleep Initiation and Maintenance Disorders/therapy , Treatment Outcome
20.
Article in Chinese | WPRIM | ID: wpr-877646

ABSTRACT

OBJECTIVE@#To observe the clinical effect of electroacupuncture (EA) on aged insomnia, and explore its possible mechanism.@*METHODS@#A total of 60 patients with aged insomnia were randomly divided into an EA group (30 cases) and a sham EA group (30 cases, 1 case dropped off). The patients in the EA group were treated with acupuncture at Baihui (GV 20), Yintang (GV 29), Shenmen (HT 7), Sanyinjiao (SP 6), Xinshu (BL 15) and Shenshu (BL 23), and EA was used at Baihui (GV 20) and Yintang (GV 29), with intermittent wave, 2 Hz in frequency. In the sham EA group, the acupoints and the EA connection acupoints were the same as those in the EA group, 2-3 mm in depth, but no current was connected. The intervention was given 30 min each time, once every other day, 3 times a week for 4 weeks in the both groups. Before and after treatment, the Pittsburgh sleep quality index (PSQI) and Montreal cognitive assessment (MoCA) scale were used to assess sleep quality and cognitive function, and serum melatonin (MT) and dopamine (DA) levels were detected.@*RESULTS@#After treatment, the total score and sub-item scores of PSQI in the EA group were lower than those before treatment (@*CONCLUSION@#Electroacupuncture can improve sleep quality and cognitive function in aged insomnia patients, and its mechanism may be related to regulating serum MT and DA levels.


Subject(s)
Acupuncture Points , Aged , Dopamine , Electroacupuncture , Humans , Melatonin , Sleep Initiation and Maintenance Disorders/therapy
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