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1.
Rev. ADM ; 79(1)ene.-feb. 2022. ilus
Article in Spanish | LILACS | ID: biblio-1362118

ABSTRACT

El angioleiomioma (AL) es una neoplasia benigna, bien circunscrita y de crecimiento lento, que representa 5% de las neoplasias de tejidos blandos y cuya etiología es desconocida. Se origina del músculo liso, mayormente de las paredes de los vasos sanguíneos; su localización es más frecuente en extremidades, siendo raros en la región de cabeza y cuello, y más aún en cavidad bucal. Histológicamente la lesión se caracteriza por ser un nódulo bien encapsulado con proliferación de fascículos de músculo liso maduro alrededor de la luz de los vasos sanguíneos, cuyas células suelen ser positivas a marcadores de inmunohistoquímica como alfa actina de músculo liso, desmina, HHF35, miosina, calponina y H-caldesmon. El tratamiento actual es la escisión quirúrgica completa con una tasa de recurrencia prácticamente nula. El objetivo es resaltar la importancia del diagnóstico y el manejo correcto de las lesiones intraorales a través de la presentación de un caso clínico de un leiomioma vascular localizado en región nasolabial, además de hacer la revisión de la literatura correspondiente (AU)


The angioleiomyoma (AL) is a benign neoplasm, well circumscribed and slow growing, that represents 5% of the soft tissue neoplasms, whose etiology is unknown. It originates from smooth muscle, mostly from the walls of blood vessels; regarding its location, it more frequently appears in the extremities, being rare in the head and neck region, and even more so in the oral cavity. Histologically, the lesion is characterized by being a well encapsulated nodule with proliferation of mature smooth muscle bundles around the lumen of the blood vessels, whose cells are usually positive for immunohistochemical markers such as alpha smooth muscle actin, desmin, HHF35, myosin, calponin and H-caldesmon. The current treatment is complete surgical excision having zero recurrence rate. The objective of the following article is to educate on the importance of correct diagnosis and management of intraoral lesions through the presentation of a clinical case of a vascular leiomyoma located in the nasolabial region, in addition to reviewing the corresponding literature (AU)


Subject(s)
Humans , Female , Adult , Soft Tissue Neoplasms , Angiomyoma , Muscle, Smooth , Biopsy , Mexico
4.
Autops. Case Rep ; 12: e2021353, 2022. tab, graf
Article in English | LILACS | ID: biblio-1360151

ABSTRACT

Pleomorphic hyalinizing angiectatic tumor (PHAT) of soft tissues is a rare, non-metastatic tumor of unknown etiology and uncertain behavior, which may recur locally. There are few reports on this condition, and due to the rarity of the disease, its lineage has not yet been fully elucidated. The present study aims to report the case of an unusual entity observed for the first time in vulval topography. A female patient, 83 years old, presented with a tumor in the vulvar region that had evolved for approximately 4 months. Magnetic resonance imaging showed an expansive perineal formation of 8.5 × 3.5 cm, and a hemivulvectomy with a flap rotation was performed. The review of the slides revealed a mesenchymal lesion without significant atypia, which was richly vascularized. In the areas of interest, the immunohistochemical (IHC) study demonstrated positivity for CD34, estrogen, and progesterone receptors; it was negative for the other tested markers. Morphological findings associated with the IHC staining panel supported the diagnosis of PHAT. The main morphological features of PHAT are clusters of ectatic vessels of different sizes that show deposits of subendothelial and intraluminal fibrin. Fusiform and pleomorphic cells randomly arranged in leaves or long fascicles intermingle these vessels. It is essential to recognize this entity and consider it among the differential diagnoses of a mesenchymal lesion, given the wide variety of entities that comprise this group of lesions.


Subject(s)
Humans , Female , Aged, 80 and over , Soft Tissue Neoplasms/pathology , Vulvar Neoplasms/pathology , Diagnosis, Differential
5.
Arch. argent. pediatr ; 119(4): e349-e352, agosto 2021. ilus
Article in Spanish | LILACS, BINACIS | ID: biblio-1281786

ABSTRACT

El rabdomiosarcoma es el tumor maligno de partes blandas más frecuente en la edad pediátrica. Puede afectar cualquier localización anatómica. El subtipo histológico alveolar suele causar lesiones en las extremidades en niños de mayor edad. Los sitios metástasicos más frecuentes son el pulmón, la médula ósea, el hueso y los ganglios linfáticos. Describimos el caso de un paciente con rabdomiosarcoma alveolar (RA) con metástasis cardíaca, una presentación poco frecuente de la patología.


Rhabdomyosarcoma is the most common malignant soft tissue tumor in pediatric age. It can affect any anatomical location. Alveolar histological subtype usually presents lesions on the extremities in older children. The most common metastatic sites are the lung, bone marrow, bone and lymph node. We describe a case of alveolar rhabdomyosarcoma with cardiac metastasis in a pediatric patient, a rare presentation of the pathology.


Subject(s)
Humans , Male , Child , Soft Tissue Neoplasms/pathology , Rhabdomyosarcoma, Alveolar/pathology , Foot Diseases/pathology , Heart Neoplasms/secondary , Rhabdomyosarcoma, Alveolar/diagnosis , Rhabdomyosarcoma, Alveolar/therapy , Ventricular Septum , Foot Diseases/diagnosis , Foot Diseases/drug therapy , Heart Neoplasms/diagnosis , Heart Neoplasms/drug therapy , Neoplasm Staging
6.
Rev. bras. ciênc. vet ; 28(3): 142-145, jul./set. 2021. il.
Article in Portuguese | LILACS, VETINDEX | ID: biblio-1363958

ABSTRACT

Os retalhos cutâneos são técnicas de escolha para reconstrução de grandes defeitos. Objetivou-se relatar o emprego do retalho de padrão axial da artéria torácica lateral em paciente com ferida cirúrgica ocasionada imediatamente após exérese de neoformação na região da articulação do cotovelo. Foi atendido paciente canino macho, 10 anos, pesando 12 kg, apresentando neoformação em tecidos moles, de grande volume, localizada na região medial do cotovelo. Como tratamento definitivo, implementou-se a exérese marginal da neoplasma seguida de reconstrução com a técnica de retalho de padrão axial da artéria torácica lateral. A técnica possibilitou completa síntese e oclusão do defeito, obtendo-se ótima recuperação pós operatória, não sendo observada deiscência de sutura ou necrose do retalho. Conclui-se que a implementação do retalho da artéria torácica lateral foi uma técnica viável na reconstrução em cotovelo após a exérese do neoplasma no paciente relatado, observando resultados satisfatórios quanto aos aspectos funcionais e cosméticos, após o período cicatricial.


Skin flaps are suitable methods of wound closure in large cutaneous defects. I The present study aims to report the use of lateral thoracic axial pattern flap to repair an elbow wound secondary to a neoplasm resection. A 10-year-old male dog weighing 12 kg was presented with a large soft tissue neoplasm in the medial aspect of the elbow. The patient underwent surgical resection of the neoplasm using the lateral thoracic cutaneous flap to achieve a complete defect closure, resulting in an excellent postoperative wound healing without suture failure or skin flap necrosis. It is concluded that the implementation of the lateral thoracic artery flap was a viable technique in elbow reconstruction after neoplasm excision in the reported patient, with satisfactory results regarding functional and cosmetic aspects after the healing period.


Subject(s)
Animals , Dogs , Soft Tissue Neoplasms/veterinary , Reconstructive Surgical Procedures/veterinary , Dogs/surgery , Free Tissue Flaps/veterinary , Surgery, Veterinary , Thoracic Arteries/surgery , Elbow , Surgical Wound/veterinary
7.
Oncol. (Guayaquil) ; 31(1): 86-92, Abril 30, 2021.
Article in Spanish | LILACS | ID: biblio-1222729

ABSTRACT

Introducción: El condrosarcoma mesenquimal extraesquelético (CME), corresponde al 1% de todos los tumores malignos de los tejidos blandos. Se localizan principalmente en la región de la cabeza y cuello, sobre todo en la órbita, y en la duramadre del cráneo, seguida de las extremidades inferiores particularmente a nivel del muslo. La ubicación pectoral es rara, motivo de reporte. Reporte de caso: Paciente hombre de 38 años quien desarrolla un nódulo de aproximadamente 2 cm de diámetro localizado en región pectoral derecha con dolor mínimo a la palpación y crecimiento rápido. Dos meses después, al momento la de resección, el nódulo mide 7.5x 6.5 x 3.5 cm, y pesa 106g. Presenta aspecto lobulado, color café grisáceo, al corte es de consistencia cauchosa y superficie blanquecina nodular con áreas centrales de aspecto mineralizado/calcificado. Se procesa 6 cortes de parafina y se diagnostica como condrosarcoma mesenquimal (CM). Evolución: El paciente fue egresado y está en control por consulta externa no ha desarrollado recidivas hasta el momento. Conclusiones: El crecimiento acelerado de una masa de consistencia cartilaginosa se correlacionó en este paciente con la presencia de un condrosarcoma mesenquimal extraesquelético.


Introduction: The extraskeletal mesenchymal chondrosarcoma (ESC) corresponds to 1% of all malignant soft tissue tumors. They are located mainly in the head and neck region, especially in the orbit, and in the dura mater of the skull, followed by the lower extremities, particularly at the level of the thigh. Pectoral location is rare, reason for report. Case report: 38-year-old male patient who developed a nodule approximately 2 cm in diameter located in the right pectoral region with minimal pain on palpation and rapid growth. Two months later, at the time of resection, the nodule measures 7.5 x 6.5 x 3.5 cm, and weighs 106g. It has a lobulated appearance, greyish brown color, when cut it is of a rubbery consistency and a nodular whitish surface with central areas of mineralized / calcified appearance. 6 paraffin sections are processed and diagnosed as mesenchymal chondrosarcoma (CM). Evolution: The patient was discharged and is being monitored by an outpatient clinic. He has not developed recurrences to date. Conclusions: The accelerated growth of a mass of cartilaginous consistency was correlated in this patient with the presence of an extraskeletal mesenchymal chondrosarcoma.


Subject(s)
Case Reports , Chondrosarcoma, Mesenchymal , Soft Tissue Neoplasms
8.
Infectio ; 25(1): 63-66, ene.-mar. 2021. tab, graf
Article in Spanish | LILACS, COLNAL | ID: biblio-1154405

ABSTRACT

Resumen La tuberculosis (TB) es una de las enfermedades infecciosas con mayor carga de morbimortalidad a nivel mundial,la presentación pulmonar es la forma más común, sin embargo, las manifestaciones extrapulmonares, especialmente las osteoarticulares, pueden ser difíciles de diagnosticar debido a sus síntomas inespecíficos sugestivos de otras entidades como neoplasias o enfermedades infiltrativas, lo que hace de su diagnóstico un reto clínico. Está enfermedad esta asociada a múltiples factores de riesgo como inmunosupresión, contacto cercano con pacientes con tuberculosis, hacinamiento, residir en zona endémica, entre otros. A continuación, se presentan dos casos de pacientes pediátricos sin compromiso inmune que cursaron con cuadros sugestivos de neoplasias musculoesqueleticas, con hallazgos imagenológicos congruentes, pero con estudios microbiológicos positivos para TB.


Abstract Tuberculosis (TB) is one of the infectious diseases with the highest burden of morbidity and mortality worldwide. Pulmonary presentation is the most common, however, extrapulmonary manifestations, especially osteoarticular, can be difficult to diagnose due to their nonspecific symptoms suggestive of other entities such as neoplasms or infiltrative diseases. Tuberculosis is also associated with multiple risk factors, especially immunosuppression, and among others, household contact with patients with tuberculosis or residing in an endemic area. We present two pediatric patients without immunecompromise, with clinical history suggestive of musculoskeletal neoplasms, with congruent imaging findings, but with positive microbiological studies for TB.


Subject(s)
Humans , Male , Female , Child , Soft Tissue Neoplasms , Tuberculosis , Patients , Communicable Diseases , Risk Factors , Mortality , Immunosuppression , Diagnosis , Neoplasms
9.
An. bras. dermatol ; 96(2): 237-239, Mar.-Apr. 2021. graf
Article in English | LILACS | ID: biblio-1248727

ABSTRACT

Abstract Granular cell tumors (GCTs) are rare soft-tissue neoplasms. GCT immunohistochemistry is positive for S-100, NSE, and CD68. This report describes the case of a 10-year-old male who presented with a dorsal nodule. A biopsy revealed aggregates and sheets of large epithelioid and spindle cells. The cells had abundant eosinophilic granular cytoplasm. Immunohistochemical analysis was positive for CD68, NKI/C3, and synaptophysin; weakly positive for NSE; and negative for S-100, SOX10, HMB45, Melan A, cytokeratin, SMA, EMA, and CD163. The Ki-67 index was less than 1%. A diagnosis of an S-100 negative, cutaneous, benign GCT was determined.


Subject(s)
Humans , Male , Child , Skin Neoplasms/diagnosis , Soft Tissue Neoplasms , Granular Cell Tumor , Skin , Immunohistochemistry , Biomarkers, Tumor
11.
Article in Chinese | WPRIM | ID: wpr-888308

ABSTRACT

OBJECTIVE@#To analyze the results of percutaneous core needle biopsy for bone tumors in upper limbs with pathologic fracture and to find the possible factors that could impact the results.@*METHODS@#The including criteria for this study was the patients who had received percutaneous core needle biopsy and definitive surgery, whose tumor was located at upper limb with pathologic fracture. From January 2015 to December 2019, seventy-seven patients were enrolled. There were 55 males and 22 females. The median age was 27 years old (range:5 to 88 years old). The tumor located at humerus in 67 cases, radius in 8 cases and ulna in 2 cases. If the pathologic diagnosis of core needle biopsy was the same with the definitive surgery, it was defined as "correct". If the pathologic diagnosis of biopsy for benign or malignant was right but the exact diagnostic name was not the same with definitive surgery, it was defined as "supportive". If the pathologic diagnosis of biopsy for benign or malignant was not correct, it was defined as "wrong". We retrospectively analyzed the accuracy and impact factors for core needle biopsy.@*RESULTS@#The result was "correct" in 63 cases(81.8%), "supportive" in 14 cases(18.2%), and "wrong" in 0 cases. We analyzed the gender, age, location, fracture displacement, the destroyed type for bone tumor, soft tissue mass, fluid area in the tumor as the factors. The results showed the rate for "correct" was significantly higher when the tumor had soft tissue mass (@*CONCLUSION@#The accuracy of percutaneous core needle biopsy for upper limb bone tumor with pathologic is high and acceptable. The biopsy chosen the soft tissue mass area can increase the accuracy.


Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Biopsy, Large-Core Needle , Bone Neoplasms , Child , Child, Preschool , Female , Fractures, Spontaneous , Humans , Male , Middle Aged , Retrospective Studies , Soft Tissue Neoplasms , Upper Extremity , Young Adult
12.
Autops. Case Rep ; 11: e2021322, 2021. graf
Article in English | LILACS | ID: biblio-1285391

ABSTRACT

Only 14 cases of extraskeletal myxoid chondrosarcoma (EMC) of the vulva have been documented in the literature. We report a case of a 63-year-old woman with EMC of the vulva confirmed by both EWSR1 and NR4A3 fluorescence in situ hybridization, the latter of which is a more specific probe for this entity. The unusual location of this tumor of prominent myxoid morphology gave rise to a wide differential diagnosis, which necessitated thorough histologic evaluation and confirmatory ancillary testing in the form of immunohistochemistry and cytogenetic studies. This article aims to review extraskeletal myxoid chondrosarcoma of the vulva and various diagnostic clues to help differentiate it from its histologic mimics. This is the fifth case of vulvar EMC in the literature with confirmation of a NR4A3 gene rearrangement.


Subject(s)
Humans , Female , Middle Aged , Soft Tissue Neoplasms , Vulva/abnormalities , Chondrosarcoma/pathology , RNA-Binding Protein EWS , Diagnosis, Differential , Nuclear Receptor Subfamily 4, Group A, Member 3
13.
Autops. Case Rep ; 11: e2020216, 2021. tab, graf
Article in English | LILACS | ID: biblio-1142395

ABSTRACT

Ossifying fibromyxoid tumor (OFMT) is a rare mesenchymal soft tissue benign neoplasm with an uncertain line of differentiation, which arises most frequently in extremities. The head and neck region involvement is uncommon, with only ten intraoral cases published in the English-language literature. One additional case of OFMT is reported here, including a literature review of intraoral reported cases. A 45-year-old female patient presented a painless nodule involving the buccal mucosa of approximately two years duration, measuring nearly 1.3 cm in maximum diameter. The main histopathological features include ovoid to round cells embedded in a fibromyxoid matrix with a perpheral shell of lamellar bone. Immunohistochemically, the tumor showed immunoreactivity for vimentin and S100. No recurrence has been detected after 7 years of follow-up.


Subject(s)
Humans , Female , Middle Aged , Soft Tissue Neoplasms/pathology , Head and Neck Neoplasms/pathology , Mouth
14.
Pesqui. vet. bras ; 40(4): 284-288, Apr. 2020. ilus
Article in English | LILACS, VETINDEX | ID: biblio-1135623

ABSTRACT

Canine soft tissue sarcomas (STS) comprise a heterogeneous group of malignancies that share similar histopathological features, a low to moderate recurrence rate and low metastatic potential. In human medicine, the expression of estrogen receptors (ER) and progesterone receptors (PR) in sarcomas has been studied to search for prognostic factors and new treatment targets. Similar studies have yet to be conducted in veterinary medicine. The objective of this study was therefore to investigate by immunohistochemistry (IHC) the ER and PR expression in a series of 80 cutaneous and subcutaneous sarcomas in dogs with histopathological features of peripheral nerve sheath tumor (PNST) and perivascular wall tumor (PWT). All cases were positive for PR and negative for ER. Tumors of high malignancy grade (grade III) exhibited higher PR expression than low-grade tumors (grade I). Tumors with mitotic activity greater than 9 mitotic figures/10 high power fields also exhibited higher PR expression. In addition, there was a positive correlation between cell proliferation (Ki67) and PR expression. Therefore, it is possible that progesterone plays a greater role than estrogen in the pathogenesis of these tumors. Future studies should explore the potential for selective progesterone receptor modulators as therapeutic agents in canine STS, as well as evaluating PR expression as a predictor of prognosis.(AU)


Sarcomas de tecidos moles (STM) caninos compreendem um grupo heterogêneo de neoplasias malignas, que apresentam alterações histopatológicas similares, baixa a moderada taxa de recorrência e baixo potencial metastático. Em medicina humana, a expressão de receptor para estrógeno (RE) e receptor para progesterona (RP) nos sarcomas tem sido estudada, visando a busca por fatores prognósticos e novos alvos para tratamentos. Na medicina veterinária, ainda não foram realizados estudos similares. O objetivo deste trabalho foi investigar por imuno-histoquímica a expressão de RE e RP em uma série de 80 sarcomas cutâneos e subcutâneos de cães, com características histopatológicas de tumor de bainha de nervo periférico e tumor de parede perivascular. Todos os casos foram positivos para RP e negativos para RE. Tumores de alto grau de malignidade (grau III) exibiram maior expressão deste receptor que os tumores de baixo grau (grau I). Tumores com atividade mitótica maior que 9 figuras mitóticas/10 campos de grande aumento também exibiram maior expressão do RP. Em adição, houve correlação positiva entre o índice de proliferação celular (Ki67) e a expressão de RP. Assim, é possível que a progesterona desempenhe maior papel que o estrógeno na patogênese desses tumores. Futuros trabalhos poderão explorar o potencial dos moduladores seletivos de RP como agente terapêutico em STM caninos, bem como avaliar a expressão de RP como preditiva de prognóstico.(AU)


Subject(s)
Animals , Male , Female , Dogs , Sarcoma , Soft Tissue Neoplasms/veterinary , Receptors, Progesterone , Receptors, Estrogen
15.
Rev. Asoc. Argent. Ortop. Traumatol ; 85(1): 65-73, mar. 2020.
Article in Spanish | LILACS, BINACIS | ID: biblio-1125539

ABSTRACT

Los tumores óseos y de partes blandas localizados en el pie son muy poco frecuentes. El lipoblastoma es una neoplasia benigna de partes blandas rara que se presenta exclusivamente en la población pediátrica, con predilección por el sexo masculino. Su asiento preferente son las extremidades, pero raramente afecta el pie. Presentamos un caso de lipoblastoma de pie en un niño de 13 meses de edad y una revisión de la bibliografía. Nivel de Evidencia: IV


Bone and soft tissue tumors of the feet are uncommon. Lipoblastoma is a rare benign soft tissue tumor, exclusive to the pediatric population, with predilection for boys. Lipoblastomas most commonly occur in the extremities, but rarely affect the foot. We present a case of lipoblastoma occurring in the foot of a 13-month-old boy, as well as our literature review. Level of Evidence: IV


Subject(s)
Infant , Soft Tissue Neoplasms , Lipoblastoma/surgery , Foot/pathology , Foot Diseases
16.
Rev. chil. radiol ; 26(1): 8-11, mar. 2020. ilus
Article in Spanish | LILACS | ID: biblio-1115519

ABSTRACT

Resumen: El hamartoma fibroso de la infancia (FHI) es una lesión rara de tejidos blandos en niños con morfología trifásica característica. El principal problema con estas lesiones es el diagnóstico diferencial con otras masas de tejidos blandos, en particular sarcomas, que requieren un afrontamiento clínico y terapéutico diferente. Presentamos un caso de un infante de 10 meses con un crecimiento asintomático de una masa axilar que, tras realizarse angioresonancia magnética y biopsia se confirmó el diagnóstico de FHI.


Abstract: Fibrous hamartomas of childhood (FHC) are rare soft tissue lesions in infants and young children with characteristic three-phase morphology.The main problem with these lesions is differentiating it from other soft tissue masses, in particular sarcomas, which require a different clinical and therapeutic approach. We present a case of a 10-month-old infant with asymptomatic growth of a left axillary mass that, after magnetic resonance angiography and biopsy, the diagnosis of FHC was confirmed.


Subject(s)
Humans , Female , Infant , Soft Tissue Neoplasms/diagnostic imaging , Hamartoma/diagnostic imaging , Fibrosis , Ultrasonography, Doppler , Magnetic Resonance Angiography , Hamartoma/pathology
17.
Rev. bras. ortop ; 55(1): 125-129, Jan.-Feb. 2020. graf
Article in English | LILACS | ID: biblio-1092676

ABSTRACT

Abstract Soft-tissue tumors are rare in the pediatric population. First described in 1969 as myxoma of the nerve sheath, the neurothekeoma is a benign tumor lesion with presumable origin in the nerve sheath. It occurs mainly in female children and presents as a mass of slow, subcutaneous growth, asymptomatic and without alteration of the local pigmentation. It is predominantly located in the head, neck, and extremities of the upper limbs. This report presents the case of a 16-year-old male with a tumor mass originating from the nerve sheath in the 4th left metacarpal, intraosseous, and relapsed after previous surgical resection 2 years before this observation. A marginal resection of the tumor mass was performed on the distal region of the fourth metacarpal, followed by curettage of the proximal phalanx and filling with structural autologous bone graft. The patient maintained a favorable postoperative clinical evolution, without local pain or range of motion limitation in his fingers. Radiologically, a progressive trabecular filling of the proximal phalanx of the fourth metacarpal was observed. At 17 months of follow-up, the patient is asymptomatic and shows no signs of relapse. The description of this case serves to increase the familiarity with this rare pathology, and aid its diagnosis and treatment.


Resumo Os tumores dos tecidos moles são raros em idade pediátrica. Descrito pela primeira vez 1969 como um mixoma da bainha nervosa, o neurotequeoma é uma lesão tumoral benigna com presumível origem na bainha nervosa. Ocorre maioritariamente em crianças do sexo feminino e apresenta-se como uma massa de crescimento lento, subcutânea, assintomática e sem alteração da pigmentação local. Localiza-se predominantemente na cabeça, no pescoço, e nas extremidades dos membros superiores. Os autores apresentam um caso clínico de um jovem de 16 anos do sexo masculino com massa tumoral com origem na bainha nervosa no 4º metacarpo esquerdo, intraóssea e recidivada após ressecção cirúrgica 2 anos antes do estudo. Foi feita ressecção marginal da massa tumoral localizada sobre a região distal do quarto metacarpo e curetagem da falange proximal e preenchimento com enxerto ósseo autólogo corticoesponjoso. O paciente apresentou uma evolução clínica pós-operatória favorável, sem queixas álgicas e sem limitações da mobilidade dos dedos da mão. Radiologicamente, foi observado preenchimento trabecular progressivo da falange proximal do quarto metacarpo. Aos 17 meses de seguimento, o paciente se encontra assintomático e não apresenta quaisquer sinais de recidiva. Com a descrição deste caso, os autores pretendem aumentar a familiaridade com essa rara patologia, seu diagnóstico e tratamento.


Subject(s)
Humans , Male , Adolescent , Pain , Soft Tissue Neoplasms , Wounds and Injuries , Biopsy , Bone and Bones , Bone Transplantation , Neurothekeoma , Hand
18.
Article in English | WPRIM | ID: wpr-876614

ABSTRACT

@#We report a case of a 33-years old, nulligravid, diagnosed with mullerian adenosarcoma with sarcomatous overgrowth (MASO), who presented with vaginal bleeding and recurrent endometrial polyp. MASO is a rare type of uterine sarcomas, it is a variant of adenosarcomas with poor prognosis. The index patient underwent primary surgical management with lymphadenectomy with a final stage of IC. Histologic diagnosis was Mulllerian adenosarcoma with sarcomatous overgrowth. A panel of immunostaining for estrogen receptors, progesterone receptors and CD 10 showed diffused positivity for the hormones with loss of CD 10 which is consistent with MASO. The rarity of MASO has a distinctive histologic features which merits meticulous sectioning as the clinical course and management vary. It has a poor prognosis due to its short and fast course of the disease.


Subject(s)
Adenosarcoma , Sarcoma , Uterine Neoplasms , Soft Tissue Neoplasms
19.
Autops. Case Rep ; 10(4): e2020189, 2020. graf
Article in English | LILACS | ID: biblio-1131847

ABSTRACT

Soft tissue tumors are not uncommon in childhood and comprise entities that range from common to very rare malignancies. Infantile fibrosarcoma (IFS) is a rare pediatric malignancy mainly seen in the first two years of life. The data about the incidence of infantile fibrosarcoma occurring in the neck in the Indian subcontinent is scarce. To the best of our knowledge, only one case of infant cervical IFS has been reported previously in the Indian subcontinent. We present another case of an eight-year-old male patient with a rapidly growing mass on the left side of the neck. He was successfully treated with a combined modality of surgery and chemotherapy with a good outcome. Among the soft tissue tumors of childhood, IFS is a rare entity. It has a good prognosis and lesser chance of distant metastasis as compared to adult fibrosarcoma. Though surgical excision is the mainstay of treatment, chemotherapy also has a significant role in the treatment of primary tumor and metastasis. We discuss the stated case to bring to the notice this uncommon cause, which can be considered as a differential diagnosis of upper cervical swellings. A better understanding of this entity would help in early diagnosis and aggressive treatment, reducing the overall morbidity and mortality.


Subject(s)
Humans , Male , Child , Rhabdomyosarcoma , Fibrosarcoma/pathology , Head and Neck Neoplasms , Soft Tissue Neoplasms/pathology , Diagnosis, Differential
20.
Artrosc. (B. Aires) ; 27(2): 69-72, 2020.
Article in Spanish | LILACS, BINACIS | ID: biblio-1118220

ABSTRACT

Se presenta un caso de presentación inusual de hemangioma arteriovenoso trombosado de rodilla, en un paciente de sexo masculino de 54 años de edad quien consulta por dolor en cara anterior e interlínea interna de rodilla izquierda, y episodios de pseudobloqueos. Sin antecedente traumático previo. Debido a la lesión meniscal interna y la sospecha diagnóstica de tumor de partes blandas de rodilla, se indicó el tratamiento quirúrgico combinado, artroscopía para la resolución de la lesión meniscal interna y, por otro abordaje, biopsia escicional con remoción del tumor de partes blandas.El estudio anatomopatológico confirmó el diagnóstico de hemangioma arteriovenoso trombosado. Tipo de estudio: Reporte de caso. Nivel de evidencia: V


We present an unusual case of thrombosed arteriovenous hemangioma of the knee. A 54-year-old male patient, with pain about de left knee, with previous blocking episodes, without prior traumatic history.Due to the internal meniscus lesion and diagnostic suspicion of soft tissue tumor of the knee. Surgical treatment was considered, both, arthroscopy and mini open surgery.Surgical treatment was performed, arthroscopy and biopsy with removal of the soft tissue tumor. Histopathological findings confirmed the diagnosis of thrombosed arteriovenous hemangioma. Type of study: Case report. Level of evidence: V


Subject(s)
Middle Aged , Soft Tissue Neoplasms , Hemangioma, Cavernous/surgery , Hemangioma, Cavernous/diagnosis , Knee Joint/surgery , Knee Joint/pathology
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