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1.
Fisioter. Mov. (Online) ; 36: e36101, 2023. tab, graf
Article in English | LILACS | ID: biblio-1421467

ABSTRACT

Abstract Introduction People with multiple sclerosis (MS) present wide and varied symptoms. Objective To investigate the impact of MS on subjects' motor and respiratory functions. Methods One hundred one participants were enrolled in this study. The subjects had previous diagnosis of relapsing-remittent MS (n = 48) or presented no neurologic diseases (n = 53, control group). Assess-ments involved mobility (Timed Get Up and Go) and balance (Berg Balance Scale) tests. A force platform was used to evaluate postural stabilometry. Respiratory functions were assessed with a portable spirometer and a digital manovacuometer. Data analyses were carried out with Student´s t-tests, chi-square, and Pearson correlation index. Significance was set at 5%. Results Compared to control peers, participants with MS showed higher motor dysfunctions affecting mobility, balance, and postural stability. Spirometry indicated normal parameters for pulmonary flows and lung capacities in both groups. The manovacuometer, differently, pointed to a respiratory muscle weakness in 48% of participants with MS. Correlation analyses highlighted that respiratory functions are more associated to dynamic than to static motor tests. Conclusion Pathological changes in MS lead to motor dysfunction on mobility, balance and postural stability. Respiratory tests showed normal pulmonary flows and lung capacities in patients with MS, but with commitment of respiratory muscle strength. Respiratory functions were more impacted by dynamic tasks rather than static motor tasks.


Resumo Introdução Pessoas com esclerose múltipla (EM) apresentam sintomas amplos e variados. Objetivo Investigar o impacto cau-sado pela EM nas funções motoras e respiratórias. Métodos Cento e um participantes foram incluídos neste estudo. Os sujeitos tinham diagnóstico prévio de EM remitente-recorrente (n = 48) ou não apresentavam doenças neurológicas (n = 53, grupo controle). As avaliações envolveram testes de mobilidade (Timed Get Up and Go) e equilíbrio (Berg Balance Scale). Uma plataforma de força foi utilizada para avaliar a estabilometria postural dos sujeitos. As funções respiratórias foram avaliadas com um espirômetro portátil e um manovacuômetro digital. A análise dos dados foi realizada pelos testes t de Student, qui-quadrado e pelo índice de correlação de Pearson. Nível de significância foi estipulado em 5%. Resultados Comparados com controles saudáveis, participantes com EM apresentaram maiores disfunções motoras que afetam mobilidade, equilíbrio e estabilidade postural. A espirometria indicou parâmetros nor-mais para fluxos pulmonares e capacidades pulmonares em ambos os grupos. A manovacuômetria, diferentemente, apontou fraqueza dos músculos respiratórios em 48% dos participantes com EM. Análises de correlação destacaram que as funções respiratórias estão mais associadas a testes motores dinâmicos do que a testes estáticos. Conclusão As alterações patológicas na EM levam à disfunção motora na mobilidade, no equilíbrio e na estabilidade postural. Os testes respiratórios mostraram padrões normais para fluxos pulmonares e capacidades pul-monares em pacientes com EM, mas com comprometimento da força muscular respiratória. As funções respiratórias foram mais afetadas por tarefas motoras dinâmicas do que por tarefas estáticas.


Subject(s)
Humans , Spirometry , Motor Activity , Multiple Sclerosis , Respiratory Function Tests , Lung Volume Measurements
2.
Rev. Univ. Ind. Santander, Salud ; 54: e302, Dec. 2022. tab, graf
Article in Spanish | LILACS | ID: biblio-1407009

ABSTRACT

Resumen Introducción: Las enfermedades no transmisibles ocupan el primer lugar de morbimortalidad en el departamento de Boyacá según las recientes estadísticas, en este grupo de enfermedades se encuentra la Enfermedad Pulmonar Obstructiva Crónica (EPOC) situación probablemente derivada de la actividad económica y ocupacional de la región. Objetivo: Caracterizar los pacientes con EPOC clínicamente estable de algunos municipios del departamento de Boyacá. Identificar los factores de riesgo. Determinar el tratamiento farmacológico y no farmacológico. Establecer características espirométricas de la población estudiada. Métodos: Estudio transversal descriptivo con muestreo aleatorio probabilístico entre febrero de 2016 a diciembre de 2018. Resultados: Se seleccionaron 248 pacientes con diagnóstico espirométrico confirmado, predominó el sexo masculino 52,8%, la edad promedio fue de 75 años, talla promedio de 1,55cm y peso promedio de 60Kg. Respecto a características demográficas el 88,3% tiene apoyo familiar y el 56,5% alcanzó escolaridad básica primaria. Respecto a la gravedad de la EPOC el 42,3% se clasificó como GOLD 1, 42,7% GOLD 2, 13,3% GOLD 3 y 1,6% GOLD 4; no se establecieron diferencias significativas en los parámetros CVF y VEF1/CVF entre grupos, mientras que VEF1 disminuyó en todos los grupos. Se observó que la medicación que reciben es en forma de monoterapia, terapia doble o terapia triple. Conclusiones: Se evidenció que casi la mitad de los pacientes en los cuatro grupos reportó contaminación del aire en espacios cerrados, aspecto similar a la exposición laboral a material particulado; no se evidenciaron diferencias significativas en los parámetros CVF y relación VEF1/CVF entre los grupos; se observó las medidas no farmacológicas se enfocan en vacunación y oxigenoterapia y las medidas farmacológicas en la administración de monoterapia y terapia triple en mayor proporción; finalmente, alrededor del 20% de los pacientes de cada uno de los grupos no reciben tratamiento farmacológico.


Abstract Introduction: Non-communicable diseases occupy the first place in morbimortality in the department of Boyaca according to recent statistics, in this group of diseases is Chronic Obstructive Pulmonary Disease (COPD) situation probably derived from the economic and occupational activity of the region. Objective: To characterize patients with clinically stable COPD in some municipalities of the Department of Boyaca. To identify risk factors. To determine pharmacological and non-pharmacological treatment. To establish spirometric characteristics of the studied population. Methods: Descriptive cross-sectional study with probabilistic random sampling between February 2016 and December 2018. Results: 248 patients with confirmed spirometric diagnosis were selected, male sex predominated 52.8%, average age was 75 years, average height of 1.55cm and average weight of 60Kg. Regarding demographic characteristics, 88.3% had family support and 56.5% had primary schooling. Regarding COPD severity, 42.3% were classified as GOLD 1, 42.7% GOLD 2, 13.3% GOLD 3 and 1.6% GOLD 4; no significant differences were established in FVC and FEV1/FVC parameters between groups, while FEV1 decreased in all groups. It was observed that the medication they receive is in the form of monotherapy, dual therapy or triple therapy. Conclusions: It was evidenced that almost half of the patients in the 4 groups reported indoor air pollution, an aspect similar to occupational exposure to particulate matter; no significant differences were evidenced in FVC parameters and FEV1/FVC ratio between groups; non-pharmacological measures focus on vaccination and oxygen therapy and pharmacological measures in the administration of monotherapy and triple therapy in greater proportion; finally, about 20% of patients in each of the groups do not receive pharmacological treatment.


Subject(s)
Humans , Male , Female , Spirometry , Therapeutics , Risk Factors , Pulmonary Disease, Chronic Obstructive
3.
Rev. Ciênc. Méd. Biol. (Impr.) ; 21(2): 172-179, out.2022. fig, tab
Article in Portuguese | LILACS | ID: biblio-1399795

ABSTRACT

Objetivo: estudos sugerem uma associação entre a doença periodontal e a doença pulmonar obstrutiva crônica (DPOC). O objetivo deste estudo foi avaliar a condição periodontal em pacientes com DPOC. Metodologia: Este estudo transversal incluiu 33 pacientes com DPOC e 30 pacientes sem DPOC (grupo controle). Todos os pacientes realizaram espirometria e foram examinados por um dentista. A condição periodontal foi avaliada através dos seguintes índices: número de dentes, índice de placa (IP), índice de sangramento gengival (IG), profundidade de sondagem (PS), PS dos sítios doentes (PSD), nível de inserção clínica (NIC), NIC dos sítios doentes (NICD) e percentual de sítios doentes (NICDP). Para análise estatística foram utilizados o teste de qui-quadrado de Pearson, o testet de Student, análise de regressão logística e cálculo do odds ratio. Resultados: O grupo DPOC apresentou maiores IP (p=0,01), NIC (p=0,001) e NICDP (p<0,001), com odds ratio de 1,2 (95%IC: 1,023­1,408). Conclusões: Os pacientes com DPOC apresentaram pior condição periodontal. Mais estudos são necessários para esclarecer o papel da terapia periodontal no protocolo de acompanhamento dos pacientes com DPOC


Objective: evidence suggests an association between periodontal disease and chronic obstructive pulmonary disease (COPD). The aim of this study was to evaluate the periodontal status in patients with COPD. Methods: this cross-sectional study included 33 patients with COPD and 30 patients without COPD (control group). All patients underwent spirometry and were examined by a dentist. Periodontal status was evaluated by the following indexes: number of teeth, plaque index (PI), gingival bleeding index (GBI), probing depth (PD), PD of diseased sites (PDD), clinical attachment level (CAL), CAL of diseased sites (CALD) and percentage of diseased sites (CALDP). The findings were analyzed under Pearson's chi-square test, independent samples t test and logistic regression with odds ratio. Results: the COPD group had higher PI (p = 0,01), CAL (p = 0,001) and CALDP (p <0,001), and the odds ratio for patients with COPD was 1.2 (95% CI: 1,023-1,408). Conclusions: patients with COPD present worse periodontal status. More studies are needed in order to clarify the role of periodontal therapy in the management of COPD.


Subject(s)
Humans , Male , Female , Adult , Periodontal Diseases , Oral Health , Pulmonary Disease, Chronic Obstructive , Chronic Periodontitis , Spirometry , Cross-Sectional Studies
4.
Medicina (Ribeirao Preto, Online) ; 55(3)set. 2022. ilus, tab
Article in English | LILACS | ID: biblio-1401851

ABSTRACT

Introdução: intervenções musicais, como canto coral, têm caráter artístico e são capazes de promover benefícios psicológicos e fisiológicos. Não há estudos na literatura sobre a repercussão do canto coral em parâmetros do sistema respiratório de escolares cantores, em comparação aos não cantores. Objetivo: comparar parâmetros do sistema respiratório entre crianças e adolescentes cantores de coral e não cantores. Método: estudo observacional transversal quantitativo incluiu escolares de 7 a 14 anos, constituindo o grupo intervenção alunos de canto coral (GCC) pareados com escolares não cantores (GNC) como controles. Realizou-se avaliação antropométrica, seguida de espirometria e manovacuometria, segundo recomendações da American Thoracic Society. Para comparação entre os grupos considerou-se os valores espirométricos absolutos e valores preditos, assim como para força de musculatura respiratória. Aplicou-se teste de Shapiro-Wilk e conduziu-se os testes U de Mann-Witney e Teste-T independente, com nível de significância de 5%. Resultados: participaram 40 crianças (95% meninas), 20 em cada grupo, com idade média de 11,25±1,80 anos no GNC e 11,20±1,64 anos no GCC. Volume expiratório forçado no primeiro segundo em porcentagem do predito (VEF1%) se apresentou maior no GNC (98,58±12,62%), em comparação ao GCC (87,10±8,84%) (p=0,001), por sua vez, GCC apresentou maior valor absoluto de pico de fluxo expiratório (PFE) (GNC:4,21±0,99l/s x GCC: 4,95±1,29l/s; p=0,048). Conclusão: os escolares cantores de canto coral não apresentaram melhores parâmetros de função pulmonar e FMR, em comparação aos não cantores (AU)


Introduction: musical interventions, such as choral singing, are artistic in character and are capable of promoting psychological and physiological benefits. There are no studies in the literature on the repercussion of choir on respiratory system parameters of practicing students compared to non-singers. Objective: compare respiratory system parameters between choir and non-choir children and adolescents. Method: cross-sectional observational study included students from 7 to 14 years old, with the intervention group constituted students of choir singing (GCC) paired with non-singing students (GNC). Anthropometric assessment was performed, followed by spirometry and manovacuometry, according to ATS recommendations. For comparison between groups, absolute spirometric values and predicted values were considered, as well as respiratory muscle strength. Shapiro-Wilk test was applied and the Mann-Witney U test and independent T-test were conducted, with a significance level of 5%. Results: 40 children (95% girls) participated, 20 in each group, with a mean age of 11.25 ± 1.80 years in the GNC and 11.20 ± 1.64 years in the GCC. Forced expiratory volume in the first second as a percentage of predicted (FEV1%) was higher in GNC (98.58 ± 12.62%) compared to GCC (87.10 ± 8.84%) (p = 0.001), GCC presented the highest absolute value of peak expiratory flow (PEF) (GNC: 4.21 ± 0.99l/s x GCC: 4.95 ± 1.29l/s; p=0.048). Conclusion: schoolchildren singing in the choir did not present better parameters of pulmonary function and FMR, compared to non-singers (AU)


Subject(s)
Humans , Child , Spirometry , Physical Therapy Modalities , Singing
5.
Rev. cuba. med ; 61(1)mar. 2022.
Article in Spanish | LILACS-Express | LILACS, CUMED | ID: biblio-1408973

ABSTRACT

Introducción: La enfermedad pulmonar obstructiva crónica es uno de los padecimientos pulmonares más frecuente a nivel mundial. Tiene repercusión sobre la mortalidad, causa importante discapacidad y afecta un número considerable de sujetos en edad productiva. La hipertensión pulmonar es una complicación usual de las enfermedades respiratorias crónicas y en particular de la pulmonar obstructiva crónica. Objetivo: Caracterizar a pacientes con enfermedad pulmonar obstructiva crónica y sospecha de hipertensión pulmonar. Métodos: Se realizó un estudio descriptivo, prospectivo en 50 pacientes atendidos en el Hospital Neumológico Benéfico Jurídico desde noviembre 2016 a enero 2018. Se analizaron variables tales como la edad, el sexo, la prueba de función ventilatoria, la radiografía de tórax, el electrocardiograma y el ecocardiograma. Resultados: De 700 pacientes portadores de enfermedad pulmonar crónica, se sospechó hipertensión pulmonar en 7 por ciento y fue confirmada en 34. Las frecuencias por sexo fueron similares y primaron los mayores de 60 años. El 41,6 por ciento de los pacientes tuvo afectación respiratoria severa, 70,6 por ciento presentó hipertensión pulmonar ligera y 64,7 por ciento tenía disnea grado 3. Los índices kappa entre las técnicas utilizadas para el diagnóstico de la hipertensión pulmonar superaron la cifra de 0,74. Conclusiones: La frecuencia de hipertensión pulmonar en pacientes con enfermedad pulmonar obstructiva crónica fue elevada. Primaron pacientes con afectación severa de la función respiratoria e hipertensión pulmonar ligera. El grado de enfermedad pulmonar obstructiva crónica no determinó la severidad de hipertensión pulmonar. Los mayores valores de concordancia entre las técnicas diagnósticas se obtuvieron para la radiografía y el ecocardiograma(AU)


Introduction: Chronic obstructive pulmonary disease is one of the most frequent, worldwide. It has impact on mortality, causing significant disability and affecting a considerable number of subjects of productive age. Pulmonary hypertension is a common complication of chronic respiratory diseases, particularly chronic obstructive pulmonary disease. Objective: To describe patients with chronic obstructive pulmonary disease and suspected pulmonary hypertension. Methods: A descriptive, prospective study was carried out in 50 patients treated at Benéfico Jurídico Pneumological Hospital from November 2016 to January 2018. Variables such as age, sex, ventilatory function test, chest X-ray, electrocardiogram and the echocardiogram were analyzed. Results: Out of 700 patients with chronic lung disease, pulmonary hypertension was suspected in 7 por ciento and confirmed in 34. The frequencies by sex were similar and those older than 60 years prevailed. 41.6 por ciento of the patients had severe respiratory involvement, 70.6 por ciento had mild pulmonary hypertension and 64.7 por ciento had grade 3 dyspnea. The kappa indices between the techniques used for the diagnosis of pulmonary hypertension exceeded the figure of 0.74. Conclusions: The frequency of pulmonary hypertension in patients with chronic obstructive pulmonary disease was high. Patients with severe impairment of respiratory function and mild pulmonary hypertension predominated. The degree of chronic obstructive pulmonary disease did not determine the severity of pulmonary hypertension. The highest concordance values between diagnostic techniques were obtained for radiography and echocardiography(AU)


Subject(s)
Humans , Male , Female , Spirometry/methods , Echocardiography/methods , Pulmonary Disease, Chronic Obstructive/epidemiology , Hypertension, Pulmonary/epidemiology , Epidemiology, Descriptive , Prospective Studies
6.
Rev. bras. med. fam. comunidade ; 17(44): 3105, 20220304. ilus, tab
Article in Portuguese | LILACS, ColecionaSUS | ID: biblio-1399860

ABSTRACT

Introdução: As doenças respiratórias crônicas estão entre os principais problemas de saúde pública no mundo. Mesmo sendo sensíveis ao tratamento na Atenção Primária à Saúde, são a terceira principal causa de morte no Brasil. Os serviços de telemedicina apresentam-se como aliados importantes dos profissionais de saúde no que tange ao manejo de doenças respiratórias como a asma e a doença pulmonar obstrutiva crônica. Objetivo: Avaliar a adequabilidade de um serviço de telemedicina diagnóstica em espirometria considerando os indicadores de oferta, utilização e cobertura populacional no estado do Rio Grande do Sul. Resultados: No período estudado, o serviço ofertou 27.672 exames de telespirometria aos usuários do Sistema Único de Saúde do Rio Grande do Sul encaminhados por médicos da Atenção Primária à Saúde. A utilização esteve abaixo de 50% da oferta em todas as macrorregiões de saúde do estado. Conclusões: O estudo demonstrou que a capacidade instalada pelo serviço esteve adequada para atender à demanda populacional do Rio Grande do Sul, no entanto a baixa utilização do serviço pode estar associada ao desconhecimento sobre ele e à dificuldade em reconhecer essas doenças por parte dos profissionais de saúde da Atenção Primária à Saúde.


Introduction: Chronic respiratory diseases are among the main public health problems in the world. Despite being sensitive to treatment in Primary Health Care, they are the third leading cause of deaths in Brazil. Telemedicine services present themselves as important allies of health professionals regarding the management of respiratory diseases such as asthma and chronic obstructive pulmonary disease. Objective: to evaluate the adequacy of a telemedicine diagnostic service in spirometry considering the indicators of supply, use and population coverage in the state of Rio Grande do Sul. Results: In the studied period, the service offered 27,672 telespirometry tests to users of the Brazilian Unified Health System referred by Primary Health Care physicians; the use was under 50% in relation to the offer in all health macro-regions of the state. Conclusions: The study demonstrated that the capacity installed by the service was adequate to meet the demand of the population in Rio Grande do Sul. However, the low usage of the service may be associated with lack of knowledge about the service and the difficulty to recognize these diseases by health professionals in Primary Health Care.


Introducción: Las enfermedades respiratorias crónicas están entre los principales problemas de salud pública en el mundo. Aunque son sensibles al tratamiento en la Atención Primaria de Salud, son la tercera principal causa de muerte en Brasil. Los servicios de telemedicina se presentan como aliados importantes de los profesionales de la salud en lo que respecta al manejo de enfermedades respiratorias como asma y Enfermedad Pulmonar Obstructiva Crónica. Objetivo: evaluar la adecuación de un servicio de telemedicina diagnóstica en espirometría considerando los indicadores de oferta, utilización y cobertura poblacional en el estado de Rio Grande do Sul. Resultados: En el período estudiado, el servicio ofertó 27.672 exámenes de telespirometría a los usuarios del Sistema Único de Salud del RS encaminados por médicos de la atención primaria de salud, la utilización estuvo por debajo del 50% de la oferta en todas las macrorregiones de salud del Rio Grande do Sul. Conclusiones: El estudio demostró que la capacidad instalada por el servicio estuvo adecuada para atender la demanda poblacional de Rio Grande do Sul, sin embargo, la baja utilización del servicio puede estar asociada al desconocimiento del servicio y a la dificultad de reconocer estas enfermedades por parte de los profesionales de salud de la atención primaria de salud.


Subject(s)
Asthma , Spirometry , Telemedicine , Pulmonary Disease, Chronic Obstructive
7.
Article in Portuguese | LILACS | ID: biblio-1368463

ABSTRACT

RESUMO: Objetivo: avaliar o comportamento de parâmetros do sistema respiratório durante internação para antibioticoterapia intravenosa (AIV) como tratamento da exacerbação pulmonar aguda (EPA) em escolares com fibrose cística (FC). Métodos: estudo do tipo analítico observacional, before-after, realizado no Hospital Infantil Joana de Gusmão, Florianópolis ­ Santa Catarina. Foram incluídas crianças com diagnóstico de FC, entre seis e 15 anos, em internação para tratamento da exacerbação pulmonar aguda, no início (T1), durante (T2) e ao final (T3) da internação foi conduzida avaliação de escores específicos de EPA, dados antropométricos e realizada avaliação dos parâmetros do sistema respiratório pelo sistema de oscilometria de impulso (IOS) e espirometria. Foram obtidos, em prontuário, dados de colonização bacteriana, genótipo, gravidade da doença (Escore de Schwachman-Doershuk-ESD) e espirometria mais recente em estabilidade clínica. Aplicou-se o teste Shapiro-Wilk para análise da distribuição dos dados e os testes ANOVA de medidas repetidas, teste de Friedman, teste T pareado e Wilcoxon, com nível de significância de 5%. Resultados: participaram 16 crianças/adolescentes (68.8% meninas, 12.88±1.67anos). Houve aumento dos parâmetros da espirometria e dados antropométricos (p<0.005) no T3, bem como redução dos escores de EPA e do X5 (p<0.005) no T3. Conclusão: os dados apresentados nesse trabalho mostram melhora dos escores de EPA, dados antropométricos, parâmetros da espirometria e do parâmetro de recolhimento elástico do IOS (X5).RESUMODescritores: Fibrose cística, Exacerbação dos sintomas, Testes de função pulmonar, Mecânica respiratória. (AU)


ABSTRACT: Objective: Evaluate the respiratory system parameters of children with cystic fibrosis (CF) during hospitalization for acute pulmonary exacerbation (APE) treatment. Methods: observational study before-after that occurred at the CF reference center. There were included children with cystic fibrosis (CF) between six to 15 years old hospitalized due to APE. The registration of the APE clinical scores, anthropometric data, and respiratory system (IOS and spirometry) evaluation occurred at the beginning (T1), during (T2), and at the end (T3) of the hospitalization. There were registered pathogens, genetic mutation, disease severity (Schwachman-Doershuk Score), and the most recent spirometry when they were clinically stable. The Shapiro-Wilk test was applied to analyze data distribution, and the repeated measure ANOVA, Friedman test, Tpaired test, and Wilcoxon test were performed to compare data, with a significance level set at 5%. Results: sixteen children/adolescents participated in the study (68.8% girls, 12.88±1.67 years old). The spirometric parameters, X5 parameter, and anthropometric data increased (p<0.005) and the APE scores decreased (p<0.005) at T3. Conclusion: APE scores, anthropometric data, spirometric parameters, and IOS elastic recoil parameter (X5) improved at the end of hospitalization.ABSTRACTKeywords: Cystic fibrosis, Symptom flare up, Respiratory function tests, Respiratory mechanics.1. Universidade do Estado de Santa Catarina ­ UDESC ­ Florianópolis, (SC) ­ Brasil https://doi.org/10.11606/issn.2176-7262.rmrp.2022.183755Tayná Castilho1, Renata Maba Gonçalves Wamosy1, Camila Isabel Santos Schivinski1Este é um artigo publicado em acesso aberto (Open Access) sob a licença Creative Commons Attribution, que permite uso, distribuição e reprodução em qualquer meio, sem restrições, desde que o trabalho original seja corretamente citado. (AU)


Subject(s)
Humans , Male , Female , Child , Adolescent , Oscillometry , Respiratory Function Tests , Spirometry , Respiratory Mechanics , Cystic Fibrosis/therapy , Symptom Flare Up
8.
J. health med. sci. (Print) ; 8(1): 21-27, ene.-mar. 2022. graf, tab
Article in Spanish | LILACS | ID: biblio-1391830

ABSTRACT

El estudio de la función pulmonar en los deportistas de alto rendimiento es importante para el correcto manejo del entrenamiento y así evitar la frecuencia de la fatiga muscular respiratoria. Lo anterior reviste mayor importancia en el fútbol, debido al elevado esfuerzo desplegado por los deportistas en sus diferentes posiciones. Determinar el efecto del entrenamiento deportivo sobre la función pulmonar en deportistas de fútbol de la división sub-20 de un equipo deportivo local de la ciudad de Pereira. Se realizó un estudio descriptivo con 40 deportistas del equipo de fútbol de la división sub-20 de la ciudad de Pereira, Colombia. A todos se les realizó la prueba de espirometría, donde se identificó su función pulmonar teniendo relevancia en la relación VEF1/CVF. Los resultados encontrados refieren que la posición más frecuente en la población estudiada es la de volante, los parámetros recolectados de la relación VEF1/CVF muestran normalidad de su función pulmonar. Los deportistas de alto rendimiento realizan la ventilación a grandes volúmenes de aire corriente y menor frecuencia respiratoria, debido, al constante estímulo a que someten el centro respiratorio y al desarrollo de los músculos respiratorios aumentando la elasticidad tóraco-pulmonar mejorando la mecánica ventilatoria, favoreciendo por tanto la ventilación alveolar, por tal razón es importante incluir dentro del entrenamiento físico y de acondicionamiento, los ejercicios respiratorios.


The study of lung function in high-performance athletes is important for the correct management of training and thus avoiding the frequency of respiratory muscle fatigue. This is more important in soccer, due to the high effort deployed by athletes in their different positions. To determine the effect of sports training on lung function in soccer athletes from the U20 division of a local sports team in the city of Pereira. A descriptive study was carried out with 40 athletes from the soccer team of the sub20 division of the city of Pereira, Colombia. All of them underwent the spirometry test, where their lung function was identified, having relevance in the FEV1 / CVF relationship. The results found refer that the most frequent position in the study population is that of a steering wheel, the parameters collected from the FEV1 / FVC ratio show normal lung function. High-performance athletes perform ventilation with large volumes of running air and a lower respiratory rate, due to the constant stimulation of the respiratory center and the development of the respiratory muscles, increasing thoracopulmonary elasticity, improving ventilatory mechanics, favoring Both alveolar ventilation, for this reason it is important to include breathing exercises within physical training and conditioning.


Subject(s)
Humans , Respiratory Function Tests/methods , Athletes/statistics & numerical data , Spirometry , Population Characteristics , Epidemiology, Descriptive , Cross-Sectional Studies , Athletic Performance
9.
Neumol. pediátr. (En línea) ; 17(2): 46-51, 2022. ilus
Article in Spanish | LILACS | ID: biblio-1379483

ABSTRACT

La fibrosis quística (FQ) es una enfermedad hereditaria autosómica recesiva, causada por la mutación del gen que codifica la proteína CFTR (cystic fibrosis transmembrane conductance regulator), afecta varios órganos, pero la enfermedad pulmonar es la primera causa de morbimortalidad. El diagnóstico a través del screening neonatal (SNN) y los nuevos tratamientos moduladores del CFTR han aumentado el interés por pesquisar y monitorizar la función pulmonar antes del inicio de los síntomas para lograr un tratamiento adecuado y oportuno con una mejor calidad de vida. Existen numerosas formas de medir la función pulmonar según la edad, colaboración y recursos disponibles. En este artículo se resumen las pruebas clásicas y las más novedosas, como técnicas de imágenes, en la búsqueda de marcadores precoces de daño pulmonar, herramientas con los que cada centro de fibrosis quística debiera contar en la era de tratamientos moduladores del CFTR, que están cambiando el pronóstico de los pacientes con esta enfermedad.


Cystic fibrosis (CF) is an autosomal recessive inherited disease, caused by mutation of the gene encoding the CFTR protein (cystic fibrosis transmembrane conductance regulator), affects several organs, but lung disease is the first cause of morbidity and mortality. Diagnosis through neonatal screening (NNS) and new CFTR modulating treatments have increased interest in screening and monitoring lung function before the onset of symptoms to achieve adequate and timely treatment with a better quality of life. There are numerous ways to measure lung function based on age, collaboration, and available resources. This article summarizes the classic and the most innovative tests, which have emerged from imaging techniques in the search for early markers of lung damage, tools that each cystic fibrosis center should have in the era of CFTR modulating treatments, which are changing the prognosis of patients with this disease.


Subject(s)
Humans , Child, Preschool , Child , Adolescent , Respiratory Function Tests/methods , Cystic Fibrosis/physiopathology , Cystic Fibrosis/diagnostic imaging , Oscillometry , Plethysmography , Spirometry , Magnetic Resonance Imaging , Radiography, Thoracic , Tomography, X-Ray Computed , Respiratory System Agents/therapeutic use , Cystic Fibrosis Transmembrane Conductance Regulator , Cystic Fibrosis/drug therapy
11.
Article in English | LILACS, BBO | ID: biblio-1422290

ABSTRACT

Abstract Objective: To quantify and compare respiratory functions and further screen the oral mucosa of tobacco and non-tobacco users. Material and Methods: First control group, non-tobacco users (n=55); Second group, smokers' group (n=168) who currently smoked cigarettes; Third group smokeless/chewing type, tobacco group (n=81); Fourth group, both smokeless and smoking type tobacco users (n=46). Fagerstrom Test for Nicotine Dependences (FTND) and Fagerström Test for Nicotine Dependence-Smokeless Tobacco (FTND-ST) instruments were used to assess nicotine dependence. Subsequently, spirometry and Toluidine Blue (TB) vital staining were performed. Chi-squared and one-way analysis of variance (ANOVA) were used for statistical analysis. Results: Fagerstrom test resulted in 48.8% of subjects with low dependency, followed by an increase in nicotine dependency from low to moderate (29.2%), moderate (15.6%), and highly dependent (6.4%) groups. All respiratory function tests and oral screening confirmed significant changes amongst tobacco and non-tobacco users. The forced vital capacity of non-smoker group was significantly different from other tobacco users' group (p<0.05). Conclusion: Early effects of tobacco use can lead to complications with the respiratory system and oral cavity. Such data can be used to delineate the harm of tobacco and should be used to urge individuals to evade the utilization of tobacco (AU).


Subject(s)
Humans , Male , Adolescent , Adult , Middle Aged , Spirometry/methods , Tobacco Use Disorder , Lung Volume Measurements/instrumentation , Mouth Mucosa/pathology , Nicotine/adverse effects , Chi-Square Distribution , Cross-Sectional Studies/methods , Surveys and Questionnaires , Analysis of Variance , India/epidemiology
12.
In. Soeiro, Alexandre de Matos; Leal, Tatiana de Carvalho Andreucci Torres; Accorsi, Tarso Augusto Duenhas; Gualandro, Danielle Menosi; Oliveira Junior, Múcio Tavares de; Caramelli, Bruno; Kalil Filho, Roberto. Manual da residência em cardiologia / Manual residence in cardiology. Santana de Parnaíba, Manole, 2 ed; 2022. p.966-973, ilus, tab.
Monography in Portuguese | LILACS | ID: biblio-1353818
13.
Rev. colomb. neumol ; 34(1): 29-38, 2022. ilus
Article in Spanish | LILACS, COLNAL | ID: biblio-1396791

ABSTRACT

La presencia de sibilantes refractarios y localizados en una sola área de auscultación en los adultos, sobre todo si están acompañados de anormalidades espirométricas y radiológicas, son a menudo la expresión clínica de una condición que requiere un proceso diagnóstico más profundo, más allá del facilista diagnóstico de asma. Entre estas anomalías se encuentran los anillos vasculares como el divertículo de Kommerel, que es una variante con una prevalencia muy baja y se caracteriza por la presencia de un arco aórtico derecho con una salida de la arteria subclavia izquierda aberrante y que provoca síntomas por la compresión de las estructuras adyacentes a estas. Aportamos en este caso clínico, el proceso diagnóstico de uno de estos hallazgos incidentales: la presencia de sibilantes localizados en una paciente joven, asintomática con una espirometría alterada que podría hacernos sospechar la presencia de broncomalacia, una aspiración de cuerpo extraño, un proceso infeccioso, tumoral o un anillo vascular que pasó desapercibido hasta la edad adulta.


The presence of refractory and localized wheezing in a single area of auscultation in adults, especially if they are accompanied by spirometric and radiological abnormalities, are often the clinical expression of a condition that requires a deeper diagnostic process, beyond the easy diagnosis of asthma. Among these abnormalities are vascular rings such as Kommerell¨s diverticulum, which is a very low prevalence variant and it is characterized by the presence of a right aortic arch with an aberrant exit from the left subclavian artery and that causes symptoms due to compression of the adjacent structures. In this clinical case, we provide the diagnosis process of one of these incidental findings, such as the presence of localized wheezing in a young asyntomatic patient with altered spirometry that could lead us to suspect the presence of bronchomalacia, foreign body aspiration, an infection, tumor or vascular ring that went unnoticed until adulthood.


Subject(s)
Humans , Asthma , Spirometry , Respiratory Sounds , Vascular Ring , Infections
14.
Rev. Méd. Inst. Mex. Seguro Soc ; 59(6): 473-481, dic. 2021. tab
Article in Spanish | LILACS | ID: biblio-1354772

ABSTRACT

Introducción: en las grandes altitudes, el intercambio gaseoso suele estar deteriorado; en la altitud moderada de la Ciudad de México esto no está aún plenamente definido. Objetivo: caracterizar el intercambio gaseoso en la altitud moderada de la Ciudad de México. Material y métodos: mediante un estudio transversal analítico se estudiaron sujetos nacidos y habitantes de la Ciudad de México, de ambos géneros, con edades de 20 a 59 años sin enfermedad cardiopulmonar. Se registraron sus variables demográficas, espirometría simple y de gasometría arterial. Las diferencias en las variables se calcularon con ANOVA de una vía para grupos independientes y ajuste de Bonferroni. Una p < 0.05 se aceptó como significativa. Resultados: se estudiaron 335 sujetos, de los cuales 168 (50.15%) fueron hombres, la edad grupal fue de 45 ± 11 años, con índice de masa corporal 22.97 ± 1.54 Kg/m2. La relación volumen espiratorio forzado en el primer segundo/Capacidad vital forzada (VEF1/CVF) de 91.58 ± 12.86%. La presión arterial de oxígeno fue de 66 ± 5.02 mmHg, el bióxido de carbono: 32.07 ± 2.66 mmHg, la saturación arterial de oxígeno: 93.03 ± 1.80% y la hemoglobina: 14.07 ± 1.52 gr/dL. Conclusiones: la presión arterial de oxígeno y del bióxido de carbono están disminuidos a la altura de la Ciudad de México.


Background: At high altitude the gas exchange is impaired, in the moderate altitude of Mexico City they are not yet defined. Objective: To characterize the gas exchange in the moderate altitude of Mexico City. Material and methods: Through an analytical cross-sectional study, subjects born and inhabitants of Mexico City, both genders, aged 20 to 59 years without cardiopulmonary disease, were studied. Their demographic variables, simple spirometry and arterial blood gas were recorded. Differences in variables were calculated with one-way ANOVA for independent groups and Bonferroni adjustment. p < 0.05 was accepted as significant. Results: 335 subjects were studied, 168 (50.15%) men. Group age 45 ± 11 years old, body mass index 22.97 ± 1.54 Kg/m2. Forced expiratory volume ratio in the first second / Forced vital capacity (FEV1/FVC) 91.58 ± 12.86%. The arterial oxygen pressure was: 66 ± 5.02 mmHg, carbon dioxide: 32.07 ± 2.66 mmHg, arterial oxygen saturation: 93.0 3 ± 1.80%, and hemoglobin: 14.07 ± 1.52 gr/dL. Conclusions: The arterial oxygen pressure and carbon dioxide are lowered at the Mexico City altitude.


Subject(s)
Humans , Male , Female , Pulmonary Heart Disease , Blood Gas Analysis , Arterial Pressure , Respiratory Function Tests , Spirometry , Forced Expiratory Volume , Pulmonary Circulation , Cross-Sectional Studies , Circulatory and Respiratory Physiological Phenomena
15.
Rev. Assoc. Méd. Rio Gd. do Sul ; 65(4): 01022105, OUT-DEZ 2021.
Article in Portuguese | LILACS | ID: biblio-1377669

ABSTRACT

RESUMO Introdução: A espirometria é um exame que avalia a função pulmonar,complementando a análise clínica.O objetivo do estudo foi avaliar a associação entre os valores do limite inferior de normalidade (LIN) e ponto de corte fixo na interpretação do distúrbio ventilatório obstrutivo (DVO), utilizando o volume expiratório forçado no 1º segundo (VEF1)/capacidade vital(CV) e VEF1/capacidade vital forçada (CVF) de crianças e adolescentes com doença pulmonar. Métodos: Estudo transversal com 358 testes espirométricos de crianças e adolescentes com doença pulmonar entre 7 e 18 anos de idade foram encaminhados ao Laboratório de Prova de Função Respiratória (LPFR) entre novembro de 2016 e dezembro de 2017. As espirometrias seguiram normas estabelecidas pela American Thoracic Society/European Respiratory Society Task Force (ATS/ERS, 2005). Na classificação do DVO foi utilizado dois critérios de interpretação da relação VEF1/CVF: ponto de corte fixos e o LIN do 50 percentil, considerado padrão ouro. Analisada a concordância através do índice Kappa de Cohen. Resultados: 316 espirometrias,mediana de idade de 12 anos(7-18) e 51,9% do sexo masculino. Observada fraca concordância entre os dois critérios (Kappa igual a 0,30). Pelo LIN do 50 percentil foi possível identificar mais casos de DVO em comparação ao ponto de corte fixo, com p<0,001. Conclusão: Identificamos fraca concordância entre os dois métodos e o LIN foi capaz de classificar mais casos de DVO quando comparados ao ponto de corte fixo. Novos estudos devem ser realizados para conclusão do assunto na faixa etária pediátrica. PALAVRA-CHAVE: Espirometria, obstrução das vias respiratórias, criança, adolescente, diagnóstico


ABSTRACT Introduction: Spirometry is a test that assesses lung function, complementing the clinical analysis. The aim of the study was to evaluate the association between the values of lower limit of normality (LLN) and fixed cut-off point in the interpretation of obstructive ventilatory disorder (OVD), using the forced expiratory volume in the 1st second (FEV1)/vital capacity (VC) and FEV1/forced vital capacity (FVC) of children and adolescents with lung disease. Methods: A cross-sectional study with 358 spirometric tests in children and adolescents with pulmonary disease between 7 and 18 years of age were referred to the Respiratory Function Test Laboratory (LPFR) between November 2016 and December 2017. Spirometry followed the standards established by the American Thoracic Society/European Respiratory Society Task Force (ATS/ERS, 2005). In the classification of OVD, two criteria were used for interpreting the FEV1/FVC ratio: fixed cutoff point and the LLN of the 50th percentile, considered the gold standard. Concordance analysis was through the Cohen's Kappa index. Through the LLN of the 50th percentile, it was possible to identify more cases of OVD compared to the fixed cutoff point, with p<0.001. Conclusion: We found a weak concordance between the two methods, and LLN was able to classify more cases of OVD as compared to the fixed cutoff point. New studies must be carried out to conclude the subject in the pediatric age group. KEYWORDS: Spirometry, airway obstruction, child, adolescent, diagnosis


Subject(s)
Humans , Child , Adolescent , Spirometry , Diagnosis , Airway Obstruction
16.
Rev. chil. enferm. respir ; 37(4): 285-292, dic. 2021. tab
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1388163

ABSTRACT

INTRODUCCIÓN: El incremento del índice de masa corporal afecta la función pulmonar en el asma. Objetivo: determinar si existen diferencias entre asmáticos con estado nutricional normal, sobrepeso y obesidad en cuanto a alteraciones de la oscilometría de impulso (IOS) y espirometría. MÉTODO: Estudio realizado en niños y adolescentes con asma persistente. Se practicó sucesivamente IOS y Espirometría pre y post- broncodilatador según criterios ATS/ERS/SER. Los pacientes se clasificaron en: eutróficos (AE), con sobrepeso (ASP) y obesos (AO). Se compararon promedios de valores basales y con respuesta broncodilatadora (RB) en espirometría e IOS, con análisis de varianzas ANOVA y test de Tukey post hoc. Se consideró un poder de 80% y error α de 5%. RESULTADOS: Se analizaron 559 pacientes, promedio de edad 9,2 años, 50,9% varones. AE 52,4%, ASP 31,3% y AO 16,3%. Se encontraron diferencias significativas entre AO vs AE (X5, AX, D5-20, VEF1/CVF, FEF25-75/CVF, RB VEF1), y entre ASP vs AE (AX, D5-20, VEF1/CVF). También se encontraron diferencias significativas en varones, no encontradas en las mujeres (X5, D5-20, VEF1/CVF, RB CVF, RB VEF1). CONCLUSIONES: Los niños asmáticos con sobrepeso y obesidad, tienen un mayor compromiso de los índices de función pulmonar medida por espirometría e IOS que los asmáticos con estado nutricional normal. Existen diferencias de género en las alteraciones espirometría e IOS.


INTRODUCTION: Increased body mass index asthma affects lung function in asthma. Objective: to determine if asthmatics with overweight or obesity have alterations in Impulse oscillometry (IOS) and spirometry compared to eutrophic METHOD: Study carried out in children and adolescents with persistent asthma. IOS-Spirometry pre and post bronchodilator were performed successively according to ATS/ERS/SER criteria. The patients were classified as: eutrophic (AE), overweight (ASP) and obese (OA). Baseline and bronchodilator response (BR) averages were compared in spirometry and IOS with ANOVA and Tukey's post hoc analysis of variance. A power of 80% and α error of 5% were considered. RESULTS: 559 patients were analyzed, mean age 9.2 years, 50.9% male. AE 52.4%, ASP 31.3% and OA 16.3%. Significant differences were found between OA vs AE (X5, AX, D5-20, FEV1/FVC, FEF25-75 / FVC, RB FEV1), and between ASP vs AE (AX, D5-20, FEV1/FVC). Significant differences were also found in men, not women (X5, D5-20, FEV1/FVC, BR FVC, BR FEV1). CONCLUSIONS: Asthmatic children with overweight and obesity have a greater compromise of pulmonary function parameters measured by spirometry and IOS than asthmatics with normal nutritional status. There are gender differences in spirometry and IOS alterations.


Subject(s)
Humans , Male , Female , Child, Preschool , Child , Adolescent , Respiratory Function Tests/methods , Asthma/physiopathology , Lung/physiopathology , Obesity/physiopathology , Oscillometry , Spirometry , Vital Capacity , Forced Expiratory Volume , Nutritional Status , Cross-Sectional Studies , Analysis of Variance , Overweight/physiopathology
17.
Biomédica (Bogotá) ; 41(3): 481-492, jul.-set. 2021. tab, graf
Article in Spanish | LILACS | ID: biblio-1345398

ABSTRACT

Resumen Introducción. El asma es una enfermedad crónica y potencialmente grave. El 80 % de los casos es de origen alérgico, por lo cual la inmunoterapia específica con alérgenos es una alternativa terapéutica que modula el curso natural de la enfermedad. Objetivo. Evaluar el impacto de la inmunoterapia en pacientes pediátricos con asma atendidos en una institución de salud de Colombia. Materiales y métodos. Se hizo un estudio observacional descriptivo con componente analítico de corte transversal. Se incluyeron 62 pacientes con diagnóstico de asma alérgica sensibilizados a ácaros del polvo y en tratamiento, mínimo, con seis dosis de inmunoterapia contra ácaros. El efecto del tratamiento se evaluó mediante la escala de puntuación del ACT (Asthma Control Test), la escala de tratamiento de la GINA (Global Initiative for Asthma) y la espirometría. Resultados. La puntuación de la prueba ACT antes del inicio de la inmunoterapia, correspondía a 30 % de pacientes con asma no controlada, 28 % con buen control y 4 % con asma totalmente controlada. Entre los pacientes con asma no controlada, el 46,7 % logró un buen control y el 23,3 % alcanzó un control total. En cuanto a la percepción de los pacientes sobre la mejoría con la inmunoterapia, el 9,75 % percibió una mejoría menor del 50 %, el 45,2 %, una entre el 50 y el 90 %, en tanto que el 41,9 % refirió una igual o mayor del 90 %. No se encontraron cambios significativos en los valores del volumen espiratorio forzado en un segundo (VEF1) en las espirometrías. Conclusiones. Se observaron cambios significativos en los puntajes del ACT y en la percepción de mejoría de la enfermedad en la población tratada con inmunoterapia específica para ácaros, es decir, que esta tendría un efecto beneficioso en el curso natural de la enfermedad


Abstract Introduction: Asthma is a chronic and potentially serious disease and 80% of the cases have an allergic etiology. In this sense, allergen-specific immunotherapy is an alternative that modulates the natural course of the disease. Objective: To evaluate the impact of immunotherapy in pediatric asthma patients treated at a health institution in Colombia. Materials and methods: We conducted an observational descriptive study with an analytical cross-sectional component. Sixty-two patients diagnosed with allergic asthma sensitized to dust mites and treated with at least 6 doses of mite immunotherapy were included. We assessed the impact of immunotherapy using the Asthma Control Test (ACT), the Global Initiative for Asthma (GINA) treatment scale, and spirometry values. Results: The ACT score before the start reported 30% of patients with uncontrolled asthma, 28% with good control, and 4% with totally controlled asthma. Of the patients with uncontrolled asthma, 46.7% achieved good control and 23.3% total control. Regarding patients' perception of improvement with the immunotherapy, 9.75% perceived a response of less than 50%, 45.2% one between 50% -90%, and 41.9% reported response equal to or greater than 90%. No significant changes in FEV1 values were found in spirometry. Conclusions: Significant changes in the ACT scores and the perception of disease improvement were observed in the population evaluated with specific mite immunotherapy, i.e., it had a positive impact on the natural course of the disease.


Subject(s)
Asthma , Immunotherapy , Pediatrics , Spirometry , Rhinitis , Mites
18.
Rev. Assoc. Méd. Rio Gd. do Sul ; 65(3): 01022105, Jul-Set 2021.
Article in Portuguese | LILACS | ID: biblio-1372389

ABSTRACT

Resumo Introdução:A espirometria é um exame que avalia a função pulmonar,complementando a análise clínica.O objetivo do estudo foi avaliar a associação entre os valores do limite inferior de normalidade(LIN) e ponto de corte fixo na interpretação do distúrbio ventilatório obstrutivo(DVO),utilizando o volume expiratório forçado no 1º segundo(VEF1)/capacidade vital(CV) e VEF1/capacidade vital forçada(CVF) de crianças e adolescentes com doença pulmonar.Métodos:Estudo transversal com 358 testes espirométricos de crianças e adolescentes com doença pulmonar entre 7 e 18 anos de idade foram encaminhados ao Laboratório de Prova de Função Respiratória(LPFR) entre novembro de 2016 e dezembro de 2017. As espirometrias seguiram normas estabelecidas pela American Thoracic Society/European Respiratory Society Task Force(ATS/ERS, 2005).Na classificação do DVO foi utilizado dois critérios de interpretação da relação VEF1/CVF:ponto de corte fixos e o LIN do 50 percentil,considerado padrão ouro.Analisada a concordância através do índice Kappa de Cohen.Resultados:316 espirometrias,mediana de idade de 12 anos(7-18) e 51,9% do sexo masculino.Observada fraca concordância entre os dois critérios (Kappa igual a 0,30).Pelo LIN do 50 percentil foi possível identificar mais casos de DVO em comparação ao ponto de corte fixo, com p<0,001.Conclusão:Identificamos fraca concordância entre os dois métodos e o LIN foi capaz de classificar mais casos de DVO quando comparados ao ponto de corte fixo. Novos estudos devem ser realizados para conclusão do assunto na faixa etária pediátrica. Palavras-chave: Espirometria, Obstrução das Vias Respiratórias, Criança, Adolescente, Diagnóstico.


Summary Introduction: Spirometry is a test that evaluates pulmonary function, complementing the clinical analysis. The objective of the study was to evaluate the association between the values ​​of the lower limit of normality (LIN) and fixed cut-off point in the interpretation of obstructive respiratory disorder (OVD) ), using forced expiratory volume in 1 second (FEV1)/vital capacity (VC) and FEV1/forced vital capacity (FVC) of children and adolescents with lung disease.Methods:Cross-sectional study with 358 spirometric tests of children and adolescents with lung disease. between 7 and 18 years of age were referred to the Respiratory Function Testing Laboratory (LPFR) between November 2016 and December 2017. Spirometry followed standards established by the American Thoracic Society/European Respiratory Society Task Force (ATS/ERS, 2005). ).In the OVD classification, two interpretation criteria were used for the FEV1/FVC ratio: fixed cut-off point and the 50th percentile LIN, considered the gold standard. concordance through Cohen's Kappa index. Results: 316 spirometries, median age of 12 years (7-18) and 51.9% male. Weak agreement between the two criteria was observed (Kappa equal to 0.30). LIN of the 50th percentile, it was possible to identify more cases of OVD compared to the fixed cut-off point, with p<0.001.Conclusion: We identified weak agreement between the two methods and the LIN was able to classify more cases of OVD when compared to the cut-off point fixed. New studies must be carried out to conclude the matter in the pediatric age group. Keywords: Spirometry, Airway Obstruction, Child, Adolescent, Diagnosis.


Subject(s)
Humans , Child , Adolescent , Spirometry , Child , Adolescent , Diagnosis , Airway Obstruction
19.
Arch. argent. pediatr ; 119(4): e340-e344, agosto 2021. tab, ilus
Article in Spanish | LILACS, BINACIS | ID: biblio-1281780

ABSTRACT

La acrodisostosis es una displasia esquelética rara, de herencia autosómica dominante, que se caracteriza por la presencia de disostosis facial y periférica, talla baja y diferentes grados de obesidad. La acrodisostosis de tipo 1, secundaria a la mutación heterocigota en el gen PRKAR1A (17q24.2), se caracteriza por la asociación de resistencia hormonal múltiple con anomalías esqueléticas. Su incidencia está infradiagnosticada debido a que comparte rasgos clínicos y de laboratorio con otras entidades como el seudohipoparatiroidismo. Presentamos el caso de una niña de 8 años, con acrodisostosis tipo 1, confirmada mediante estudio genético. Además del fenotipo característico descrito, la talla baja y la resistencia hormonal, la paciente presentó una afectación progresiva de la función pulmonar: un patrón pulmonar obstructivo no reversible. En la literatura revisada, no se han encontrado otros casos que describan esta asociación entre acrodisostosis y afectación respiratoria.


Acrodysostosis is a rare skeletal displasia, of autosomal dominant inheritance, characterized by the presence of facial and peripheral dysostosis, short stature and obesity. Type 1 acrodysostosis is secondary to a mutation in the PRKAR1A (17q24.2) gene, which results in multi hormonal resistance and skeletal anomalities. This syndrome is under-diagnosed as it shares analytical and clinical characteristics with other entities, such as pseudohypoparathyroidism. We report the case of an eight-year-old girl with genetically confirmed type 1 acrodysostosis. In addition to the characteristic phenotype described, the short stature and the hormonal resistance, the patient suffered a progressive lung function deterioration: an irreversible pulmonary obstructive pattern. We have not found in previous literature cases reporting an association between acrodysostosis and lung function impairement.


Subject(s)
Humans , Female , Child , Osteochondrodysplasias/complications , Dysostoses/complications , Lung Diseases, Obstructive/complications , Osteochondrodysplasias/genetics , Osteochondrodysplasias/diagnostic imaging , Spirometry , Diagnosis, Differential , Dysostoses/genetics , Dysostoses/diagnostic imaging , Dyspnea/complications , Mutation/genetics
20.
Cuad. Hosp. Clín ; 62(1): 38-45, jun. 2021. ilus.
Article in Spanish | LILACS | ID: biblio-1284260

ABSTRACT

OBJETIVOS: determinar las principales características demográficas, clínicas, radiológicas y de función pulmonar de los pacientes con bronquiectasias en la Clínica del Pulmón. MATERIAL Y MÉTODOS: estudio observacional, retrospectivo. Se revisaron las historias clínicas de 23 pacientes con diagnóstico de dilataciones bronquiales. RESULTADOS: de los 23 pacientes, con una edad media de 49,4 ± 3,87 años, 13 corresponden al sexo femenino y 10 al sexo masculino, el tiempo de evolución de la enfermedad desde el diagnóstico de la patología inicial es de 17,3 ± 2,92 años. La tuberculosis es la etiología principal en 15 pacientes (65,2%). Las manifestaciones clínicas más frecuentes son la tos y expectoración mucopurulenta por varios años en la mayoría de los pacientes, al que añadimos la disnea y hemoptisis, la auscultación pulmonar revela la presencia de crépitos en 17 pacientes (73,9%). La Tomografía de Tórax de Alta Resolución distingue dos tipos de bronquiectasias: La sacular o quística y la cilíndrica, de localización unilobar, bilobar y multilobar (difuso). La Espirometría Forzada fue indicada en 10 pacientes (43,5%) 7 mujeres y 3 varones, el Síndrome Bronquial Obstructivo fue el hallazgo más frecuente. La asociación de Tetraciclina con Metronidazol indicado en 9 pacientes (39,1%) mejoró el cuadro clínico. La fisiopatología de esta entidad clínica está sujeta a una constante actualización. CONCLUSIONES: en pacientes tosedores crónicos, las bronquiectasias deben tener prioridad diagnóstica, se trata de una patología antigua, pero de actualidad permanente.


The purpose of this document is to determine the main epidemiological and clinical characteristics of patients with bronchiectasis at the Lung Clinic. METHOD: observational, retrospective study. The medical records of 23 patients diagnosed with bronchial dilation were reviewed. RESULTS: the results of the 23 patients studied, with a mean age of 49,4 ± 3,87 years, 13 correspond to the female sex and 10 to the male sex, indicate that the time of evolution of the disease from the diagnosis of the initial pathology is: 17,3 ± 2,92 years. Tuberculosis is the main etiology in 15 patients (65,2%). The most frequent clinical manifestations were cough and mucopurulent expectoration of several years in most of the patients, to which we must add dyspnea and hemoptysis, pulmonary auscultation reveals the presence of crepitus in 17 patients (73,9%). High Resolution Chest Tomography distinguishes two types of bronchiectasis: the saccular or cystic and the cylindrical, the localization is unilobar, bilobar and multilobar (diffuse). Forced spirometry was indicated in 10 patients (43,5%), 7 women and 3 men, Chronic Obstructive Pulmonary Disease is the main diagnosis. The association of Tetracycline with Metronidazole indicated in 9 patients (39,1%) had positive results. The pathophysiology of this clinical entity is subject to constant updating. CONCLUSIONS: in chronic coughing patients, bronchiectasis must have diagnostic priority, it is an old pathology, but it is permanently current


Subject(s)
Humans , Male , Female , Middle Aged , Bronchiectasis , Pulmonary Disease, Chronic Obstructive , Auscultation , Spirometry , Tuberculosis , Dyspnea , Hemoptysis , Metronidazole
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