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1.
Article in Spanish | LILACS | ID: biblio-1535455

ABSTRACT

Introducción: La espirometría es una prueba de función pulmonar usada en la valoración de programas de rehabilitación para evaluar exposiciones a tóxicos y alérgenos, en estudios epidemiológicos y en el desarrollo de ecuaciones de referencia en poblaciones específicas; estos valores pueden variar de acuerdo con la altura. Objetivo: Establecer las diferencias entre los valores de referencia de espirometría forzada en población adulta residentes en alturas mayores y menores a 1500 metros sobre el nivel del mar. Métodos: Revisión sistemática, se encontraron 536 estudios, se evaluaron 66 en texto completo, 33 en calidad metodológica con las listas de chequeo Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies y Quality Assessment of Case-Control Studies; 21 estudios fueron seleccionados para la revisión y 12 surtieron metanálisis. Resultados: Se contó con 48 923 participantes de alturas entre 2,4 y 4440 m s. n. m. Hay diferencias iniciales al relacionar la altura (+/-1500 m s. n. m) con el VEF1 (hombres: DM 0,29; IC: 0,03-0,55; mujeres: DM 0,27; IC: -0,07-0,60) y los valores de referencia con el sexo: CVF (DM 1,31; IC: 1,24-1,37) y VEF1 (DM: 1,03; IC: 0,95-1,11). Se reportó alta heterogeneidad y riesgo de sesgo de publicación. Discusión: Estas diferencias se dan en función de aspectos antropométricos y fisiológicos como la aclimatación y el envejecimiento pulmonar. Los mecanismos que influyen en estos cambios son la adaptación genética, molecular, fisiológica y anatómica, que permiten compensar los efectos de la hipoxia aguda o crónica, lo cual aumenta la ventilación alveolar y los valores espirométricos. Conclusiones: Los valores de referencia de espirometría varían de acuerdo con la altura (mayores en alturas > 1500 m s. n. m) y el sexo (más elevados en hombres). Es necesario contar con evidencias más amplias y contundentes en la temática.


Introduction: Spirometry is a lung function test used in the evaluation of rehabilitation programs to evaluate exposures to toxics and allergens in epidemiological studies and in the development of reference equations in specific populations; these values may vary according to height. Objective: To establish the differences between the reference values of forced spirometry in the adult population living at altitudes greater than and less than 1,500 meters above sea level. Methods: Systematic review a total of 536 studies were found; 66 were assessed in full text and 33 were assessed for methodological quality using the Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies and Quality Assessment of Case-Control Studies checklists; 21 studies were selected for the review and 12 provided meta-analyses. Results: There were 48,923 participants from heights between 2.4 and 4,440 m.a.s.l. There are initial differences when relating height (+/-1,500 m.a.s.l.) with FEV1 (men: MD 0.29; CI: 0.03-0.55; women: MD 0.27; CI: -0.07-0 .60); and the reference values with gender: FVC (MD 1.31, CI: 1.24-1.37) and FEV1 (MD: 1.03, CI: 0.95-1.11). High heterogeneity and risk of publication bias are reported. Discussion: These differences occur based on anthropometric and physiological aspects such as acclimatization and lung aging. The mechanisms that influence these changes are genetic, molecular, physiological and anatomical adaptations that allow compensation for the effects of acute or chronic hypoxia, which increases alveolar ventilation and spirometric values. Conclusions: The spirometry reference values vary according to height (higher at heights >1,500 m.a.s.l.) and sex (higher in men). It is necessary to have broader and more convincing evidence on the subject.


Subject(s)
Humans , Reference Values , Spirometry , Pulmonary Medicine , Adult , Altitude , Demography , Meta-Analysis , Systematic Review
2.
Article in English | LILACS | ID: biblio-1551161

ABSTRACT

Objective: Evaluate the spirometry pattern of patients who persisted with respiratory symptoms after infection with SARS-Cov-2. Methods: Cross-sectional, observational, retrospective study in a single center, approved by the local Ethics Committee (registration number: 5,120,720). Patients who underwent spirometry due to Post-Covid Syndrome were evaluated to analyze the spirometric pattern presented. The following were collected: exam identification data, sex, age, symptom time, the need for mechanical ventilation, and quality of spirometry, in addition to the following exam parameters: FVC, FEV1, FEV1/FVC, FEV 25-75/FVC, and FEV 75, evaluating the Lower Limit of Normality, pre-bronchodilator and post-bronchodilator values. Results: Data from 72 patients were collected. Of these, 55.5% of patients had spirometry results within normal limits. The most frequent respiratory alteration was obstructive respiratory disorder, present in 29.2% of the patients. Conclusions: The presence of dyspnea in patients with normal spirometry may indicate further evaluation of lung function and other etiologies for dyspnea (AU).


Objetivo: Avaliar o padrão de espirometria de pacientes que persistiram com sintomas respiratórios após a infecção pelo SARS-CoV-2. Métodos: Estudo transversal, observacional e retrospectivo realizado em um único centro, aprovado pelo Comitê de Ética local (número do parecer: 5.120.720). Foram avaliados pacientes submetidos a espirometria devido à Síndrome Pós-Covid, a fim de analisar o padrão espirométrico apresentado. Os seguintes dados foram coletados: identificação do exame, sexo, idade, tempo de sintomas, necessidade de ventilação mecânica, qualidade da espirometria, além dos seguintes parâmetros do exame: CVF, VEF1, VEF1/CVF, VEF 25-75/CVF e VEF 75, avaliando o Limite Inferior da Normalidade, valores pré-broncodilatador e pós-broncodilatador. Resultados: Foram coletados dados de 72 pacientes. Destes, 55,5% apresentaram resultados espirométricos dentro dos limites normais. A alteração respiratória mais frequente foi o distúrbio ventilatório obstrutivo, presente em 29,2% dos pa-cientes. Conclusões: A presença de dispneia em pacientes com espirometria dentro da normalidade pode indicar uma avaliação adicional da função pulmonar, assim como outras etiologias para a dispneia (AU).


Subject(s)
Humans , Male , Female , Respiratory Function Tests , Spirometry , Dyspnea , Post-Acute COVID-19 Syndrome
3.
Int. j. morphol ; 41(5): 1485-1491, oct. 2023. ilus, tab
Article in Spanish | LILACS | ID: biblio-1521047

ABSTRACT

Los pacientes con COVID-19 subsidiarios de ventilación mecánica (VM), evolucionan con consecuencias funcionales en la musculatura ventilatoria y apendicular que no necesariamente se abordan de manera diferenciada. El objetivo de esta investigación fue evaluar el impacto de un programa de recuperación funcional en estos pacientes y determinar si las intervenciones afectan de manera diferenciada a las funciones ventilatorias y musculatura apendicular, utilizando pruebas de bajo costo. Se evaluaron 47 pacientes con COVID-19 que estuvieron en VM. Posterior a una espirometría basal se les realizó; presión inspiratoria máxima (PIMáx), fuerza de prensión palmar (FPP), prueba de pararse y sentarse (PPS) y Prueba de caminata en 6 minutos (PC6m), antes y después del plan de intervención. Este programa incluyó ejercicios aeróbicos y de fuerza supervisados por dos sesiones semanales de 60 minutos durante 3 meses. Después del programa, se observaron mejoras significativas en la capacidad vital forzada (CVF), el volumen espiratorio en el primer segundo (VEF1) y la PIMáx. Se encontraron relaciones significativas entre estas mediciones y la distancia recorrida de la PC6m, la FPP y la PPS. En conclusión, el programa de recuperación funcional en pacientes con COVID-19 que requirieron VM, beneficia tanto la función ventilatoria como la fuerza muscular apendicular. Las pruebas de fuerza muscular apendicular pueden ser útiles para evaluar la recuperación ya que pueden entregar información diferenciada de sus rendimientos. Por último, se necesita más investigación para comprender mejor la respuesta de estos pacientes a la rehabilitación.


SUMMARY: Patients with COVID-19 requiring mechanical ventilation (MV) evolve with functional consequences in the ventilatory and appendicular muscles that are not necessarily addressed in a differentiated manner. The objective of this research was to evaluate the impact of a functional recovery program in these patients and determine if the interventions differentially affect ventilatory functions and appendicular muscles, using low- cost tests. 47 patients with COVID-19 who were on MV were evaluated. After a baseline spirometry, they were performed; maximum inspiratory pressure (MIP), handgrip strength (HGS), sit to stand test (STST) and 6-minute walk test (6MWT), before and after the intervention plan. This program included supervised aerobic and strength exercises for two weekly 60-minute sessions for 3 months. After the program, significant improvements were observed in forced vital capacity (FVC), expiratory volume in the first second (FEV1) and MIP. Significant relationships were found between these measurements and the distance traveled of the 6MWT, the HGS and the STST. In conclusion, the functional recovery program in patients with COVID-19 who required MV benefits both ventilatory function and appendicular muscle strength. Appendicular muscle strength tests can be useful to evaluate recovery since they can provide differentiated information about your performances. Finally, more research is needed to better understand the response of these patients to rehabilitation.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Pulmonary Ventilation/physiology , Recovery of Function , COVID-19/rehabilitation , Respiration, Artificial , Spirometry , Walking , Hand Strength , Maximal Respiratory Pressures
4.
Acta neurol. colomb ; 39(2)jun. 2023.
Article in Spanish | LILACS | ID: biblio-1533486

ABSTRACT

Introducción: El compromiso respiratorio en la enfermedad de Pompe es una de sus manifestaciones más frecuentes, tiene un impacto negativo en la calidad de vida y facilita la aparición de múltiples complicaciones. Se puede presentar como parte evolutiva de la enfermedad o incluso ser el síntoma inicial de la patología. Contenidos: La presentación clínica del compromiso respiratorio en la enfermedad de Pompe se caracteriza por disnea, ortopnea, cefalea y tos, y sus cambios paraclínicos incluyen hipercapnia, policitemia, elevación del índice de apnea/hipopnea, así como disminución de la capacidad vital y de las presiones inspiratoria y espiratorias máximas. El compromiso respiratorio es causado principalmente por disfunción muscular (especialmente el diafragma) y alteración de la regulación del sistema nervioso central. Conclusiones: Es fundamental la valoración acuciosa inicial de los patrones respiratorios y por supuesto su seguimiento, el cual dependerá del tipo de progresión de la disfunción respiratoria (rápida o lenta) o del requerimiento específico para cada paciente (ventilación no invasiva o invasiva).


Introduction: Respiratory compromise in Pompe disease is one of the most frequent manifestations, which has a negative impact on quality of life and leads to multiple complications. This can occur as an evolutionary part of the disease, or even be the initial symptom of the pathology. Contents: Its clinical presentation is characterized by dyspnea, orthopnea, headache, and cough, and its paraclinical changes include hypercapnia, polycythemia, elevated apnea/hypopnea index, decreased vital capacity, and decreased maximum inspiratory and expiratory pressures. Respiratory compromise is caused mainly by muscular dysfunction (especially the diaphragm) and alteration of regulation of the central nervous system. Conclusions: An initial careful assessment of respiratory patterns is essential, and of course their follow-up, that will depend of the type of progression of respiratory dysfunction (rapid or slow) or the specific requirement for each patient (non-invasive or invasive ventilation).


Subject(s)
Spirometry , Glycogen Storage Disease Type II , Vital Capacity , Noninvasive Ventilation , Apnea , Polysomnography , Dyspnea
5.
Rev. Ciênc. Méd. Biol. (Impr.) ; 22(1): 12-17, jun 22, 2023. tab
Article in Portuguese | LILACS | ID: biblio-1442751

ABSTRACT

Introdução: em março de 2020, a pandemia do SARS-CoV-2 foi declarada pela OMS, contabilizando mais de seis milhões de mortes e 600 milhões de casos confirmados. São necessários estudos para compreender a persistência dos sintomas após a infecção aguda, que podem se correlacionar com a gravidade inicial da doença. Objetivo: avaliar e comparar as características clínicas, espirométricas e radiológicas dos pacientes acometidos pela síndrome pós-COVID, estratificados conforme gravidade da infecção aguda pelo SARS-CoV-2. Metodologia: trata-se de estudo de corte transversal, realizado a partir de consultas ambulatoriais em amostra de conveniência. O estudo incluiu 232 pacientes, atendidos de novembro de 2020 a outubro de 2021. Os pacientes foram divididos em 2 grupos: com COVID-19, sem internamento em unidade de terapia intensiva; e com internamento em unidade de terapia intensiva. Resultados: foram avaliados 232 pacientes acometidos pela COVID-19, sendo 69,4% do sexo feminino; idade média de 50 ± 12,8 anos. As comorbidades mais frequentes foram hipertensão arterial sistêmica (44,0%) e diabetes mellitus (21,1%). Dos pacientes estudados, 45,7% foram internados durante a fase aguda da doença, sendo que cinquenta (21,6%) foram alocados em unidade de terapia intensiva (UTI). Em relação à espirometria, o padrão de distúrbio restritivo foi verificado apenas nos pacientes internados em UTI. Na tomografia de tórax, o padrão de pneumonia em organização foi associado a pacientes que precisaram de internamento em unidade de terapia intensiva. Conclusão: este estudo evidencia que o distúrbio ventilatório restritivo e a presença de pneumonia em organização tiveram associação com quadros iniciais mais graves.


Introduction: in March 2020, the SARS-CoV-2 pandemic was declared by the WHO, accounting for more than six million deaths and 600 million confirmed cases. Studies are required to understand the persistence of symptoms after acute infection, which may correlate with the initial severity of the disease. Objective: to evaluate and compare the clinical, spirometric and radiological characteristics of patients affected by the post-COVID syndrome, stratified according to the severity of the acute infection by SARS-CoV-2. Methodology: this is a cross-sectional study, carried out from outpatient consultations in a convenience sample. The study included 232 patients, seen from November 2020 to October 2021. Patients were divided into 2 groups: with COVID-19, without admission to an intensive care unit; and with admission to the intensive care unit. Results: 232 patients affected by COVID-19 were evaluated, 69.4% of whom were female; average age of 50 ± 12.8 years. The most common comorbidities were systemic arterial hypertension (44.0%) and diabetes mellitus (21.1%). Of the patients studied, 45.7% were hospitalized during the acute phase of the disease, and fifty (21.6%) were allocated to an intensive care unit (ICU). Regarding spirometry, the pattern of restrictive disorder was verified only in patients admitted to the ICU. On chest tomography, the pattern of organizing pneumonia was associated with patients who required admission to the intensive care unit. Conclusion: this study shows that restrictive ventilatory disorder and the presence of organizing pneumonia were associated with more severe initial conditions.


Subject(s)
Humans , Male , Female , Middle Aged , SARS-CoV-2 , Pneumonia , Spirometry , Tomography , Cross-Sectional Studies
6.
Int. j. morphol ; 41(2): 437-444, abr. 2023. ilus, tab
Article in Spanish | LILACS | ID: biblio-1440312

ABSTRACT

Los objetivos del presente estudio fueron primero evaluar la asociación de dimensiones antropométricas de tórax y tronco con índices espirométricos, segundo, ajustar una ecuación de predicción con dimensiones antropométricas de tronco y tercero, comparar nuestro modelo predictivo con dos ecuaciones diagnósticas. Se evaluaron 59 estudiantes universitarios entre 20 y 40 años, de ambos sexos, sin hábito tabáquico. Las variables consideradas fueron: edad, sexo, peso, estatura, diámetro transverso de tórax, diámetro anteroposterior de tórax, perímetro de tórax, altura de tórax, altura de tronco, flujo espiratorio máximo (FEM), volumen espiratorio forzado en el primer segundo (VEF1) y capacidad vital forzada (CVF). Se utilizó el análisis de regresión múltiple para estimar los valores espirométricos en función de las variables demográficas y antropométricas. La CVF y el VEF1 tienen asociación lineal directa con el diámetro transverso de tórax, altura de tórax, perímetro de tórax y altura de tronco. Se ajustó una ecuación de regresión lineal múltiple que indicó que es posible estimar la CVF y el VEF11 en función de la altura de tronco y el perímetro de tórax para ambos sexos. Estas variables son capaces de explicar el 74 % de los valores de CVF y el 68 % de los valores de VEF1. Al comparar los valores obtenidos por nuestras ecuaciones predictivas con las ecuaciones de referencia nacional observamos que nuestros resultados son más cercanos a los de Quanjer et al. (2012) que a los de Knudson et al. (1983). La altura de tronco y el perímetro de tórax tienen asociación directa con el VEF1 y CVF y son buenos predictores del VEF1 y CVF en estudiantes universitarios. Nuestros valores estimados son más cercanos a las ecuaciones de Quanjer et al. (2012) en comparación a las estimaciones de Knudson (1983).


SUMMARY: The purposes of the present study were first to evaluate the association between anthropometric dimensions of the thorax and trunk with spirometric indices, second, to fit a prediction equation with anthropometric dimensions of the trunk, and third, to compare our predictive model with two diagnostic equations. Fifty-nine university students between 20 and 40 years old, of both sexes and non-smokers were recruited. Variables considered were age, sex, weight, height, chest transverse diameter, chest anteroposterior diameter, chest perimeter, chest height, trunk height, maximum expiratory flow (PEF), forced expiratory volume in the first second (FEV1) and forced vital capacity (FVC). Multiple regression analysis was used to estimate spirometric values based on demographic and anthropometric variables. FVC and FEV1 have a direct linear association with chest transverse diameter, chest height, chest circumference, and trunk height. A multiple linear regression equation was fitted, indicating that it is possible to estimate FVC and FEV1 as a function of trunk height and chest girth for both sexes. These variables can explain 74% of the FVC values and 68% of the FEV1 values. Comparing the values obtained by our predictive equations with the national reference equations, we observe that our results are closer to those of Quanjer et al. (2012) than to those of Knudson et al. (1983). Trunk height and chest circumference have a direct association with FEV1 and FVC and are good predictors of FEV1 and FVC in university students. Our estimated values are closer to Quanjer et al. (2012) than Knudson et al. (1983) prediction equations.


Subject(s)
Humans , Male , Female , Adult , Young Adult , Spirometry , Anthropometry , Torso/anatomy & histology , Torso/physiology , Thorax/anatomy & histology , Thorax/physiology , Vital Capacity/physiology , Forced Expiratory Volume/physiology , Regression Analysis
7.
Rev. am. med. respir ; 23(1): 50-53, mar. 2023. graf
Article in Spanish | LILACS, BINACIS | ID: biblio-1514922

ABSTRACT

Paciente femenina de 22 años con antecedente de asma bronquial desde la infancia. Fue derivada al servicio de broncoscopia para ser evaluada por sospecha de tumor endoluminal. Trae a la consulta una espirometría normal. En la tomografía de tórax, se observa una lesión endoluminal en el bronquio fuente izquierdo (BFI). Además de disminución volumétrica del campo pulmonar izquierdo con lateralización mediastínica homolateral y herniación del pulmón derecho hacia la izquierda. En el examen físico, se constataron sibilancias generalizadas en el campo pulmonar izquierdo, sin otra alteración.


Subject(s)
Female , Spirometry
8.
Rev. Pesqui. Fisioter ; 13(1)fev., 2023. tab, ilus
Article in English, Portuguese | LILACS | ID: biblio-1531232

ABSTRACT

INTRODUCTION: Diaphragm is the primary inspiratory muscle and it plays an essential role in controlling the spine during postural control. In nonspecific low back pain, the diaphragm muscle becomes weak, due to which the pulmonary functions may decrease. To the best of our knowledge there is a scarcity of literature in regard to the effect of low back pain on pulmonary parameters. Thus, the study is aimed to evaluate the pulmonary function in patients with non-specific low back pain. METHODS: One hundred and thirteen patients with non-specific low back pain and 113 BMI matched normal individuals as a comparison group aged 18-40 years of male and female genders were recruited by purposive sampling method for this prospective cross-sectional study. The non-specific back pain group included participants diagnosed with non-specific low back pain with pain intensity > 3 on VAS scale and duration > 3 months. After initial screening and assessment, anthropometric characteristics were recorded. Then, the pulmonary function test (FEV1, FVC, FEV1/ FVC, PEFR, SVC, MVV) were recorded in both groups. RESULT: Kolmogorov-Smirnov test was used for normality assessment and data was found to be not normally distributed. Non parametric data was represented as median and IQR (Inter Quartile Range). Between groups data analysis was performed by using MannWhitney U test and the effect size was computed for the study variables. P < 0.05 was considered as statistically significant. There was a significant difference in pulmonary function values of FEV1, FEV1/FVC, PEFR, SVC, MVV. There was no significant difference in age and BMI of the participants of both groups. CONCLUSION: There exist significant differences in pulmonary function in patients with non-specific low back pain.


INTRODUÇÃO: O diafragma é o principal músculo inspiratório e desempenha um papel essencial no controle da coluna durante o controle postural. Na dor lombar inespecífica, o músculo diafragma torna-se fraco, podendo as funções pulmonares diminuir. Até onde sabemos, há escassez de literatura a respeito do efeito da dor lombar nos parâmetros pulmonares. Assim, o estudo tem como objetivo avaliar a função pulmonar em pacientes com dor lombar inespecífica. MÉTODOS: Cento e treze pacientes com dor lombar inespecífica e 113 indivíduos normais pareados com IMC como grupo de comparação com idades entre 18 e 40 anos, dos gêneros masculino e feminino, foram recrutados por método de amostragem proposital para este estudo transversal prospectivo. O grupo de dor nas costas inespecífica incluiu participantes com diagnóstico de dor lombar inespecífica com intensidade de dor > 3 na escala VAS e duração > 3 meses. Após triagem e avaliação inicial, as características antropométricas foram registradas. Em seguida, foram registrados os testes de função pulmonar (VEF1, CVF, VEF1/CVF, PFE, CVL, VVM) em ambos os grupos. RESULTADO: O teste de Kolmogorov-Smirnov foi utilizado para avaliação da normalidade e os dados não apresentaram distribuição normal. Os dados não paramétricos foram representados como mediana e IQR (intervalo interquartil). A análise dos dados entre grupos foi realizada pelo teste U de Mann-Whitney e o tamanho do efeito foi calculado para as variáveis do estudo. < 0,05 foi considerado estatisticamente significativo. Houve diferença significativa nos valores de função pulmonar de VEF1, VEF1/CVF, PFE, CVL, VVM. Não houve diferença significativa na idade e no IMC dos participantes de ambos os grupos. CONCLUSÃO: Existem diferenças significativas na função pulmonar em pacientes com dor lombar inespecífica.


Subject(s)
Respiratory Muscles , Spirometry , Low Back Pain
9.
Fisioter. Mov. (Online) ; 36: e36101, 2023. tab, graf
Article in English | LILACS | ID: biblio-1421467

ABSTRACT

Abstract Introduction People with multiple sclerosis (MS) present wide and varied symptoms. Objective To investigate the impact of MS on subjects' motor and respiratory functions. Methods One hundred one participants were enrolled in this study. The subjects had previous diagnosis of relapsing-remittent MS (n = 48) or presented no neurologic diseases (n = 53, control group). Assess-ments involved mobility (Timed Get Up and Go) and balance (Berg Balance Scale) tests. A force platform was used to evaluate postural stabilometry. Respiratory functions were assessed with a portable spirometer and a digital manovacuometer. Data analyses were carried out with Student´s t-tests, chi-square, and Pearson correlation index. Significance was set at 5%. Results Compared to control peers, participants with MS showed higher motor dysfunctions affecting mobility, balance, and postural stability. Spirometry indicated normal parameters for pulmonary flows and lung capacities in both groups. The manovacuometer, differently, pointed to a respiratory muscle weakness in 48% of participants with MS. Correlation analyses highlighted that respiratory functions are more associated to dynamic than to static motor tests. Conclusion Pathological changes in MS lead to motor dysfunction on mobility, balance and postural stability. Respiratory tests showed normal pulmonary flows and lung capacities in patients with MS, but with commitment of respiratory muscle strength. Respiratory functions were more impacted by dynamic tasks rather than static motor tasks.


Resumo Introdução Pessoas com esclerose múltipla (EM) apresentam sintomas amplos e variados. Objetivo Investigar o impacto cau-sado pela EM nas funções motoras e respiratórias. Métodos Cento e um participantes foram incluídos neste estudo. Os sujeitos tinham diagnóstico prévio de EM remitente-recorrente (n = 48) ou não apresentavam doenças neurológicas (n = 53, grupo controle). As avaliações envolveram testes de mobilidade (Timed Get Up and Go) e equilíbrio (Berg Balance Scale). Uma plataforma de força foi utilizada para avaliar a estabilometria postural dos sujeitos. As funções respiratórias foram avaliadas com um espirômetro portátil e um manovacuômetro digital. A análise dos dados foi realizada pelos testes t de Student, qui-quadrado e pelo índice de correlação de Pearson. Nível de significância foi estipulado em 5%. Resultados Comparados com controles saudáveis, participantes com EM apresentaram maiores disfunções motoras que afetam mobilidade, equilíbrio e estabilidade postural. A espirometria indicou parâmetros nor-mais para fluxos pulmonares e capacidades pulmonares em ambos os grupos. A manovacuômetria, diferentemente, apontou fraqueza dos músculos respiratórios em 48% dos participantes com EM. Análises de correlação destacaram que as funções respiratórias estão mais associadas a testes motores dinâmicos do que a testes estáticos. Conclusão As alterações patológicas na EM levam à disfunção motora na mobilidade, no equilíbrio e na estabilidade postural. Os testes respiratórios mostraram padrões normais para fluxos pulmonares e capacidades pul-monares em pacientes com EM, mas com comprometimento da força muscular respiratória. As funções respiratórias foram mais afetadas por tarefas motoras dinâmicas do que por tarefas estáticas.


Subject(s)
Humans , Spirometry , Motor Activity , Multiple Sclerosis , Respiratory Function Tests , Lung Volume Measurements
10.
Neumol. pediátr. (En línea) ; 18(1): 12-13, 2023. ilus
Article in Spanish | LILACS | ID: biblio-1442719

ABSTRACT

Tradicionalmente se ha definido la respuesta broncodilatadora (RB) positiva como una mejoría ≥ de 12 % del VEF1. En el año 2022 se publica una Guía sobre la interpretación de función la pulmonar de la Sociedad Americana de Tórax y la Sociedad Europea de Enfermedades Respiratorias, donde se propone que la RB debe expresarse como el cambio porcentual del VEF1 en relación con el VEF1 predicho y que un cambio ≥ 10 % indica una RB positiva. Las sociedades científicas en Chile están evaluando estas recomendaciones para decidir su adecuada implementación en pediatría.


Traditionally, a positive bronchodilator (BR) response has been defined as a ≥ 12% improvement in FEV1. In the year 2022, a Guide on the interpretation of pulmonary function of the American Thoracic Society and the European Society of Respiratory Diseases was published, where it was proposed that BR should be expressed as the percent change in FEV1 relative to predicted FEV1 and that a change ≥ 10% indicates a positive BR. Scientific societies in Chile are evaluating these recommendations to decide their proper implementation in pediatrics.


Subject(s)
Humans , Child , Respiratory Tract Diseases/physiopathology , Spirometry , Bronchodilator Agents/pharmacology , Forced Expiratory Volume
11.
Rev. chil. enferm. respir ; 39(3): 2016-225, 2023. tab, graf
Article in Spanish | LILACS | ID: biblio-1521830

ABSTRACT

Introducción: Se han informado patrones de deterioro temprano de la función pulmonar en el asma pediátrica. Nuestro objetivo fue identificar las trayectorias de la función pulmonar en la espirometría, desde la edad preescolar hasta la edad escolar. Materiales: Estudio prospectivo realizado entre el 2016 y el 2021. Se reclutaron pacientes con asma persistente a quienes se les realizó oscilometría de impulso (IOS)-espirometría al inicio y después de 3 años. La espirometría anormal se definió de acuerdo con las guías ATS/ERS. Métodos: se utilizó χ2 y ANOVA para comparar las características clínicas y promedios de parámetros de la espirometría e IOS entre trayectorias. Resultados: 86 pacientes, promedio de edad 5,3 y 8,3 años en su primera y segunda evaluación. El 70,9% de los pacientes mantuvo la espirometría normal en ambas evaluaciones (trayectoria 1), el 9,3% presentó espirometría preescolar anormal que normalizó en la edad escolar (trayectoria 2) y el 19,8% espirometría en anormal en ambas evaluaciones (trayectoria 3). La trayectoria 3 registró menor peso promedio al nacer (2,4 kg vs 3,02 kg p = 0,04), mayor promedio de exacerbaciones (5,3 vs 2,01 p = 0,00002), mayor promedio de hospitalizaciones (0,61 vs 0,16 p = 0,04), parámetros promedio más bajos en espirometría (relación VEF1/CVF %, relación VEF0,75/CVF %, VEF0,75 L, VEF0,5 L), promedios más bajos en X5 kPa/Ls y más altos en AX kPa/Ls, que la trayectoria 1. Conclusiones: La trayectoria 1 fue la más frecuente, con persistencia de función pulmonar normal. La trayectoria 3, la segunda más frecuente, inició seguimiento con función pulmonar disminuida en la espirometría y disfunción de vía aérea pequeña en el IOS que se mantuvo en la edad escolar. Los niños que siguieron la trayectoria 3 tuvieron menor peso al nacer, más exacerbaciones y hospitalizaciones que los niños de la trayectoria 1.


Introduction: Patterns of early decline in lung function have been reported in pediatric asthma. Our objective was to identify pulmonary function trajectories in spirometry, from preschool age to school age. Materials: Prospective study conducted between 2016 and 2021. Patients with persistent asthma who underwent impulse oscillometry (IOS)-spirometry at baseline and after 3 years were recruited. Abnormal spirometry was defined according to ATS/ERS guidelines. Methods: χ2 and ANOVA was used to compare clinics characteristics and means of IOS-spirometry parameters between trajectories. Results: 86 patients, mean age of 5,3 and 8,3 years in their first and second evaluation. 70.9% of the patients maintained normal spirometry in both evaluations (Track 1), 9.3% presented abnormal preschool spirometry that normalized at school age (Track 2) and 19.8% abnormal spirometry in both evaluations (Track 3). Trajectory 3 had a lower average birth weight (2,4 kg vs 3,02 kg p = 0,04), higher average of exacerbations (5,3 vs 2,01 p = 0,00002), higher average of hospitalizations (0,61 vs 0,16 p = 0,04), lowest averages parameters in spirometry (FEV1/FVC % ratio, FEV0,75/FVC % ratio, FEV0,75 L, FEV0,5 L), lower average in X5 kPa/Ls and higher in AX kPa/Ls, than trajectory 1. Conclusions: Trajectory 1 was the most common, with persistent normal lung function. Trajectory 3, the second most frequent, started follow-up with decreased lung function in spirometry and small airway disfunction in the IOS that were maintained at school age. Children who followed trajectory 3 had lower birth weight, more exacerbations, and hospitalizations than children in trajectory 1.


Subject(s)
Humans , Male , Female , Child, Preschool , Child , Asthma/physiopathology , Oscillometry , Spirometry , Vital Capacity , Forced Expiratory Volume , Prospective Studies , Analysis of Variance
12.
Rev. chil. enferm. respir ; 39(3): 226-232, 2023. tab, graf
Article in Spanish | LILACS | ID: biblio-1521831

ABSTRACT

El asma se caracteriza por su impacto deletéreo que incluye gran coste económico para el sistema de salud. En pacientes con asma mal controlada a pesar del tratamiento, se propone un régimen de mantenimiento con corticoides inhalados y formoterol. El objetivo del presente estudio observacional retrospectivo fue evaluar las modificaciones espirométricas tras el cambio del medicamento controlador en pacientes con asma moderada a severa asistidos en el Hospital Clínico de Magallanes de Punta Arenas, así como también cuantificar la modificación en el número de exacerbaciones graves (consulta a un servicio de urgencia y/u hospitalización por asma). Participaron 61 adultos con asma moderada a severa (mediana de edad: 60 años [rango: 21-87], mujeres: 69,4%; comorbilidad atópica/alérgica: 79%; otras comorbilidades: 46,8%) en los que se cambió el tratamiento con fluticasona/salmeterol 250/25 μg por budesónida/formoterol 160/4,5 μg. No se observaron cambios significativos en los índices espirométricos tras el cambio. Con el tratamiento inicial, el 46,9% presentó ≥ 1 visita a urgencias (total: 50 consultas). Tras el cambio por budesonida/formoterol, el 21% requirió al menos una visita a urgencias (total: 14 consultas; p < 0,01). La proporción de pacientes con ≥ 2 consultas a urgencias fue de 19,7% con el tratamiento basal y de 1,6% tras el cambio a budesonida/formoterol (p < 0,01). No se observaron diferencias significativas en la cantidad de hospitalizaciones. En este estudio del mundo real de pacientes con asma moderada a grave, el cambio del tratamiento a budesonida/formoterol se asoció con reducción significativa de las consultas a urgencias, a pesar de no detectarse cambios de significación estadística en los índices espirométricos habituales.


Asthma is characterized by its deleterious impact, including a high cost to the healthcare system. In patients with poorly controlled asthma despite treatment, a maintenance regimen of inhaled corticosteroids and formoterol is proposed. The aim of this retrospective, observational study was to evaluate the spirometric changes after switching the controller medication in patients with moderate to severe asthma attended in our institution ("Hospital Clínico de Magallanes"), as well as the variation in the number of severe exacerbations (consultation to an emergency department and/or hospitalization for asthma). Sixty-one adults with moderate to severe asthma (median age: 60 years-old [range: 21-87], women: 69.4%; atopic/allergic comorbidity: 79%; other comorbidities: 46.8%) in whom treatment with fluticasone/salmeterol 250/25 μg was switched to budesonide/formoterol 160/4.5 μg participated in our study. No significant changes in spirometric parameters were observed after the replacement treatment. With the initial treatment, 46.9% patients presented ≥ 1 visit to the emergency department (total: 50 visits). After the switch to budesonide/formoterol, 21% required at least one emergency department visit (total: 14 consultations; p < 0.01). The proportion of patients with ≥ 2 emergency department visits was 19.7% with baseline treatment and 1.6% after switching to budesonide/formoterol (p < 0.01). No significant differences were observed in the number of hospitalizations. In this real-world study of moderate to severe asthma patients, switching to budesonide/formoterol was associated with a significant reduction in emergency department visits, despite no statistically significant changes in the usual spirometric parameters.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Young Adult , Asthma/drug therapy , Spirometry , Budesonide/administration & dosage , Formoterol Fumarate/administration & dosage , Bronchodilator Agents/administration & dosage , Drug Administration Schedule , Forced Expiratory Volume , Retrospective Studies , Drug Therapy, Combination , Fluticasone-Salmeterol Drug Combination/administration & dosage
13.
Acta toxicol. argent ; 30(3): 3-3, dic. 2022.
Article in Spanish | LILACS | ID: biblio-1447115

ABSTRACT

Resumen La contaminación del aire interior es un problema de salud pública, ya que afecta a unos 2.600 millones de personas en todo el mundo que siguen cocinando con combustibles sólidos como la madera, los residuos de las cosechas, etc. Esta exposición aumenta el factor de riesgo de desarrollo de enfermedades crónicas. La población indígena es muy susceptible a estar expuesta a mezclas de contaminantes del humo de leña como los Hidrocarburos Aromáticos Policíclicos (HAPs) debido a los métodos tradicionales de cocción. El objetivo de este trabajo fue evaluar la exposición a HAPs por medio de 10 metabolitos hidroxilados en orina de la población indígena de la Huasteca Potosina, mediante cromatografía de gases acoplada a espectrometría de masas; por otro lado, la salud renal y pulmonar fueron evaluadas con una prueba general de orina y la toxina urémica Indoxil sulfato, esta fue evaluada por medio cromatografía líquida de alto rendimiento, y la función pulmonar con una espirometría. Los resultados indican la presencia de metabolitos hidroxilados en el 89,47% de las muestras de orina, los más frecuentes fueron el 1-OH-PIRENO, el 1,2-OH-NAFTALENO. El Indoxil sulfato se presentó en el 100% de las muestras y la media era de 193,4 ± 91,85 gg/L En cuanto a la salud pulmonar, los resultados indican que algunos sujetos presentan patrones respiratorios regulares e irregulares. Estos resultados indican que la población se encuentra expuesta de manera crónica a una mezcla de contaminantes en el aire que podría producir el desarrollo de daño en los pulmones y los riñones y aumentar el riesgo al desarrollo de enfermedades crónicas.


Abstract Interior air pollution is a public health concern, it affects about 2.6 billion people around the world who still cook using solid fuels such as wood, crop wastes, among others. This exposition increases the risk of the development of non-communicable diseases (NCDs). The indigenous population is very susceptible to being exposed to mixtures of pollutants from the wood smoke such as Polycyclic Aromatic Hydrocarbons (PAHs) due to traditional methods of cooking, heating and waste burning. Therefore, the objective of this work was to evaluate the exposure to PAHs through the application of 10 hydroxylated metabolites (OH-PAHs) in the urine of the indigenous population from the Huasteca Potosina, this by gas chromatography coupled to mass spectrometry and to assess renal health of the population at the time of the study, with a general test of urine and through the uremic toxin Indoxyl Sulfate (IS), this by high-performance liquid chromatography, and the and pulmonary health with spirometry. The results indicate the presence OH-PAHs in 89.47% of the urine samples, the most frequent metabolites were 1-OH-PYRENE, 2-OH-NAPTHALENE. IS was present in 100% of the samples in mean concentrations of 193.4 ± 91.85 gg/L. For pulmonary health, the results indicate some subjects have regular and irregular respiratory patterns. These results indicate that the population is highly exposed to a mixture of pollutants in the air that might damage the lungs and kidneys and increase the risk of NCDs development.


Subject(s)
Humans , Male , Female , Middle Aged , Polycyclic Aromatic Hydrocarbons/adverse effects , Air Pollution, Indoor , Health of Indigenous Peoples , Phytoalexins/urine , Spirometry/methods , Mexico
14.
Rev. Ciênc. Méd. Biol. (Impr.) ; 21(2): 172-179, out.2022. fig, tab
Article in Portuguese | LILACS | ID: biblio-1399795

ABSTRACT

Objetivo: estudos sugerem uma associação entre a doença periodontal e a doença pulmonar obstrutiva crônica (DPOC). O objetivo deste estudo foi avaliar a condição periodontal em pacientes com DPOC. Metodologia: Este estudo transversal incluiu 33 pacientes com DPOC e 30 pacientes sem DPOC (grupo controle). Todos os pacientes realizaram espirometria e foram examinados por um dentista. A condição periodontal foi avaliada através dos seguintes índices: número de dentes, índice de placa (IP), índice de sangramento gengival (IG), profundidade de sondagem (PS), PS dos sítios doentes (PSD), nível de inserção clínica (NIC), NIC dos sítios doentes (NICD) e percentual de sítios doentes (NICDP). Para análise estatística foram utilizados o teste de qui-quadrado de Pearson, o testet de Student, análise de regressão logística e cálculo do odds ratio. Resultados: O grupo DPOC apresentou maiores IP (p=0,01), NIC (p=0,001) e NICDP (p<0,001), com odds ratio de 1,2 (95%IC: 1,023­1,408). Conclusões: Os pacientes com DPOC apresentaram pior condição periodontal. Mais estudos são necessários para esclarecer o papel da terapia periodontal no protocolo de acompanhamento dos pacientes com DPOC


Objective: evidence suggests an association between periodontal disease and chronic obstructive pulmonary disease (COPD). The aim of this study was to evaluate the periodontal status in patients with COPD. Methods: this cross-sectional study included 33 patients with COPD and 30 patients without COPD (control group). All patients underwent spirometry and were examined by a dentist. Periodontal status was evaluated by the following indexes: number of teeth, plaque index (PI), gingival bleeding index (GBI), probing depth (PD), PD of diseased sites (PDD), clinical attachment level (CAL), CAL of diseased sites (CALD) and percentage of diseased sites (CALDP). The findings were analyzed under Pearson's chi-square test, independent samples t test and logistic regression with odds ratio. Results: the COPD group had higher PI (p = 0,01), CAL (p = 0,001) and CALDP (p <0,001), and the odds ratio for patients with COPD was 1.2 (95% CI: 1,023-1,408). Conclusions: patients with COPD present worse periodontal status. More studies are needed in order to clarify the role of periodontal therapy in the management of COPD.


Subject(s)
Humans , Male , Female , Adult , Periodontal Diseases , Oral Health , Pulmonary Disease, Chronic Obstructive , Chronic Periodontitis , Spirometry , Cross-Sectional Studies
15.
Medicina (Ribeirao Preto, Online) ; 55(3)set. 2022. ilus, tab
Article in English | LILACS | ID: biblio-1401851

ABSTRACT

Introdução: intervenções musicais, como canto coral, têm caráter artístico e são capazes de promover benefícios psicológicos e fisiológicos. Não há estudos na literatura sobre a repercussão do canto coral em parâmetros do sistema respiratório de escolares cantores, em comparação aos não cantores. Objetivo: comparar parâmetros do sistema respiratório entre crianças e adolescentes cantores de coral e não cantores. Método: estudo observacional transversal quantitativo incluiu escolares de 7 a 14 anos, constituindo o grupo intervenção alunos de canto coral (GCC) pareados com escolares não cantores (GNC) como controles. Realizou-se avaliação antropométrica, seguida de espirometria e manovacuometria, segundo recomendações da American Thoracic Society. Para comparação entre os grupos considerou-se os valores espirométricos absolutos e valores preditos, assim como para força de musculatura respiratória. Aplicou-se teste de Shapiro-Wilk e conduziu-se os testes U de Mann-Witney e Teste-T independente, com nível de significância de 5%. Resultados: participaram 40 crianças (95% meninas), 20 em cada grupo, com idade média de 11,25±1,80 anos no GNC e 11,20±1,64 anos no GCC. Volume expiratório forçado no primeiro segundo em porcentagem do predito (VEF1%) se apresentou maior no GNC (98,58±12,62%), em comparação ao GCC (87,10±8,84%) (p=0,001), por sua vez, GCC apresentou maior valor absoluto de pico de fluxo expiratório (PFE) (GNC:4,21±0,99l/s x GCC: 4,95±1,29l/s; p=0,048). Conclusão: os escolares cantores de canto coral não apresentaram melhores parâmetros de função pulmonar e FMR, em comparação aos não cantores (AU)


Introduction: musical interventions, such as choral singing, are artistic in character and are capable of promoting psychological and physiological benefits. There are no studies in the literature on the repercussion of choir on respiratory system parameters of practicing students compared to non-singers. Objective: compare respiratory system parameters between choir and non-choir children and adolescents. Method: cross-sectional observational study included students from 7 to 14 years old, with the intervention group constituted students of choir singing (GCC) paired with non-singing students (GNC). Anthropometric assessment was performed, followed by spirometry and manovacuometry, according to ATS recommendations. For comparison between groups, absolute spirometric values and predicted values were considered, as well as respiratory muscle strength. Shapiro-Wilk test was applied and the Mann-Witney U test and independent T-test were conducted, with a significance level of 5%. Results: 40 children (95% girls) participated, 20 in each group, with a mean age of 11.25 ± 1.80 years in the GNC and 11.20 ± 1.64 years in the GCC. Forced expiratory volume in the first second as a percentage of predicted (FEV1%) was higher in GNC (98.58 ± 12.62%) compared to GCC (87.10 ± 8.84%) (p = 0.001), GCC presented the highest absolute value of peak expiratory flow (PEF) (GNC: 4.21 ± 0.99l/s x GCC: 4.95 ± 1.29l/s; p=0.048). Conclusion: schoolchildren singing in the choir did not present better parameters of pulmonary function and FMR, compared to non-singers (AU)


Subject(s)
Humans , Child , Spirometry , Physical Therapy Modalities , Singing
16.
Rev. cuba. med ; 61(1)mar. 2022.
Article in Spanish | LILACS, CUMED | ID: biblio-1408973

ABSTRACT

Introducción: La enfermedad pulmonar obstructiva crónica es uno de los padecimientos pulmonares más frecuente a nivel mundial. Tiene repercusión sobre la mortalidad, causa importante discapacidad y afecta un número considerable de sujetos en edad productiva. La hipertensión pulmonar es una complicación usual de las enfermedades respiratorias crónicas y en particular de la pulmonar obstructiva crónica. Objetivo: Caracterizar a pacientes con enfermedad pulmonar obstructiva crónica y sospecha de hipertensión pulmonar. Métodos: Se realizó un estudio descriptivo, prospectivo en 50 pacientes atendidos en el Hospital Neumológico Benéfico Jurídico desde noviembre 2016 a enero 2018. Se analizaron variables tales como la edad, el sexo, la prueba de función ventilatoria, la radiografía de tórax, el electrocardiograma y el ecocardiograma. Resultados: De 700 pacientes portadores de enfermedad pulmonar crónica, se sospechó hipertensión pulmonar en 7 por ciento y fue confirmada en 34. Las frecuencias por sexo fueron similares y primaron los mayores de 60 años. El 41,6 por ciento de los pacientes tuvo afectación respiratoria severa, 70,6 por ciento presentó hipertensión pulmonar ligera y 64,7 por ciento tenía disnea grado 3. Los índices kappa entre las técnicas utilizadas para el diagnóstico de la hipertensión pulmonar superaron la cifra de 0,74. Conclusiones: La frecuencia de hipertensión pulmonar en pacientes con enfermedad pulmonar obstructiva crónica fue elevada. Primaron pacientes con afectación severa de la función respiratoria e hipertensión pulmonar ligera. El grado de enfermedad pulmonar obstructiva crónica no determinó la severidad de hipertensión pulmonar. Los mayores valores de concordancia entre las técnicas diagnósticas se obtuvieron para la radiografía y el ecocardiograma(AU)


Introduction: Chronic obstructive pulmonary disease is one of the most frequent, worldwide. It has impact on mortality, causing significant disability and affecting a considerable number of subjects of productive age. Pulmonary hypertension is a common complication of chronic respiratory diseases, particularly chronic obstructive pulmonary disease. Objective: To describe patients with chronic obstructive pulmonary disease and suspected pulmonary hypertension. Methods: A descriptive, prospective study was carried out in 50 patients treated at Benéfico Jurídico Pneumological Hospital from November 2016 to January 2018. Variables such as age, sex, ventilatory function test, chest X-ray, electrocardiogram and the echocardiogram were analyzed. Results: Out of 700 patients with chronic lung disease, pulmonary hypertension was suspected in 7 por ciento and confirmed in 34. The frequencies by sex were similar and those older than 60 years prevailed. 41.6 por ciento of the patients had severe respiratory involvement, 70.6 por ciento had mild pulmonary hypertension and 64.7 por ciento had grade 3 dyspnea. The kappa indices between the techniques used for the diagnosis of pulmonary hypertension exceeded the figure of 0.74. Conclusions: The frequency of pulmonary hypertension in patients with chronic obstructive pulmonary disease was high. Patients with severe impairment of respiratory function and mild pulmonary hypertension predominated. The degree of chronic obstructive pulmonary disease did not determine the severity of pulmonary hypertension. The highest concordance values between diagnostic techniques were obtained for radiography and echocardiography(AU)


Subject(s)
Humans , Male , Female , Spirometry/methods , Echocardiography/methods , Pulmonary Disease, Chronic Obstructive/epidemiology , Hypertension, Pulmonary/epidemiology , Epidemiology, Descriptive , Prospective Studies
17.
Article in Portuguese | LILACS | ID: biblio-1368463

ABSTRACT

RESUMO: Objetivo: avaliar o comportamento de parâmetros do sistema respiratório durante internação para antibioticoterapia intravenosa (AIV) como tratamento da exacerbação pulmonar aguda (EPA) em escolares com fibrose cística (FC). Métodos: estudo do tipo analítico observacional, before-after, realizado no Hospital Infantil Joana de Gusmão, Florianópolis ­ Santa Catarina. Foram incluídas crianças com diagnóstico de FC, entre seis e 15 anos, em internação para tratamento da exacerbação pulmonar aguda, no início (T1), durante (T2) e ao final (T3) da internação foi conduzida avaliação de escores específicos de EPA, dados antropométricos e realizada avaliação dos parâmetros do sistema respiratório pelo sistema de oscilometria de impulso (IOS) e espirometria. Foram obtidos, em prontuário, dados de colonização bacteriana, genótipo, gravidade da doença (Escore de Schwachman-Doershuk-ESD) e espirometria mais recente em estabilidade clínica. Aplicou-se o teste Shapiro-Wilk para análise da distribuição dos dados e os testes ANOVA de medidas repetidas, teste de Friedman, teste T pareado e Wilcoxon, com nível de significância de 5%. Resultados: participaram 16 crianças/adolescentes (68.8% meninas, 12.88±1.67anos). Houve aumento dos parâmetros da espirometria e dados antropométricos (p<0.005) no T3, bem como redução dos escores de EPA e do X5 (p<0.005) no T3. Conclusão: os dados apresentados nesse trabalho mostram melhora dos escores de EPA, dados antropométricos, parâmetros da espirometria e do parâmetro de recolhimento elástico do IOS (X5).RESUMODescritores: Fibrose cística, Exacerbação dos sintomas, Testes de função pulmonar, Mecânica respiratória. (AU)


ABSTRACT: Objective: Evaluate the respiratory system parameters of children with cystic fibrosis (CF) during hospitalization for acute pulmonary exacerbation (APE) treatment. Methods: observational study before-after that occurred at the CF reference center. There were included children with cystic fibrosis (CF) between six to 15 years old hospitalized due to APE. The registration of the APE clinical scores, anthropometric data, and respiratory system (IOS and spirometry) evaluation occurred at the beginning (T1), during (T2), and at the end (T3) of the hospitalization. There were registered pathogens, genetic mutation, disease severity (Schwachman-Doershuk Score), and the most recent spirometry when they were clinically stable. The Shapiro-Wilk test was applied to analyze data distribution, and the repeated measure ANOVA, Friedman test, Tpaired test, and Wilcoxon test were performed to compare data, with a significance level set at 5%. Results: sixteen children/adolescents participated in the study (68.8% girls, 12.88±1.67 years old). The spirometric parameters, X5 parameter, and anthropometric data increased (p<0.005) and the APE scores decreased (p<0.005) at T3. Conclusion: APE scores, anthropometric data, spirometric parameters, and IOS elastic recoil parameter (X5) improved at the end of hospitalization.ABSTRACTKeywords: Cystic fibrosis, Symptom flare up, Respiratory function tests, Respiratory mechanics.1. Universidade do Estado de Santa Catarina ­ UDESC ­ Florianópolis, (SC) ­ Brasil https://doi.org/10.11606/issn.2176-7262.rmrp.2022.183755Tayná Castilho1, Renata Maba Gonçalves Wamosy1, Camila Isabel Santos Schivinski1Este é um artigo publicado em acesso aberto (Open Access) sob a licença Creative Commons Attribution, que permite uso, distribuição e reprodução em qualquer meio, sem restrições, desde que o trabalho original seja corretamente citado. (AU)


Subject(s)
Humans , Male , Female , Child , Adolescent , Oscillometry , Respiratory Function Tests , Spirometry , Respiratory Mechanics , Cystic Fibrosis/therapy , Symptom Flare Up
18.
J. health med. sci. (Print) ; 8(1): 21-27, ene.-mar. 2022. graf, tab
Article in Spanish | LILACS | ID: biblio-1391830

ABSTRACT

El estudio de la función pulmonar en los deportistas de alto rendimiento es importante para el correcto manejo del entrenamiento y así evitar la frecuencia de la fatiga muscular respiratoria. Lo anterior reviste mayor importancia en el fútbol, debido al elevado esfuerzo desplegado por los deportistas en sus diferentes posiciones. Determinar el efecto del entrenamiento deportivo sobre la función pulmonar en deportistas de fútbol de la división sub-20 de un equipo deportivo local de la ciudad de Pereira. Se realizó un estudio descriptivo con 40 deportistas del equipo de fútbol de la división sub-20 de la ciudad de Pereira, Colombia. A todos se les realizó la prueba de espirometría, donde se identificó su función pulmonar teniendo relevancia en la relación VEF1/CVF. Los resultados encontrados refieren que la posición más frecuente en la población estudiada es la de volante, los parámetros recolectados de la relación VEF1/CVF muestran normalidad de su función pulmonar. Los deportistas de alto rendimiento realizan la ventilación a grandes volúmenes de aire corriente y menor frecuencia respiratoria, debido, al constante estímulo a que someten el centro respiratorio y al desarrollo de los músculos respiratorios aumentando la elasticidad tóraco-pulmonar mejorando la mecánica ventilatoria, favoreciendo por tanto la ventilación alveolar, por tal razón es importante incluir dentro del entrenamiento físico y de acondicionamiento, los ejercicios respiratorios.


The study of lung function in high-performance athletes is important for the correct management of training and thus avoiding the frequency of respiratory muscle fatigue. This is more important in soccer, due to the high effort deployed by athletes in their different positions. To determine the effect of sports training on lung function in soccer athletes from the U20 division of a local sports team in the city of Pereira. A descriptive study was carried out with 40 athletes from the soccer team of the sub20 division of the city of Pereira, Colombia. All of them underwent the spirometry test, where their lung function was identified, having relevance in the FEV1 / CVF relationship. The results found refer that the most frequent position in the study population is that of a steering wheel, the parameters collected from the FEV1 / FVC ratio show normal lung function. High-performance athletes perform ventilation with large volumes of running air and a lower respiratory rate, due to the constant stimulation of the respiratory center and the development of the respiratory muscles, increasing thoracopulmonary elasticity, improving ventilatory mechanics, favoring Both alveolar ventilation, for this reason it is important to include breathing exercises within physical training and conditioning.


Subject(s)
Humans , Respiratory Function Tests/methods , Athletes/statistics & numerical data , Spirometry , Population Characteristics , Epidemiology, Descriptive , Cross-Sectional Studies , Athletic Performance
19.
Rev. Univ. Ind. Santander, Salud ; 54(1): e302, Enero 2, 2022. tab, graf
Article in Spanish | LILACS | ID: biblio-1407009

ABSTRACT

Resumen Introducción: Las enfermedades no transmisibles ocupan el primer lugar de morbimortalidad en el departamento de Boyacá según las recientes estadísticas, en este grupo de enfermedades se encuentra la Enfermedad Pulmonar Obstructiva Crónica (EPOC) situación probablemente derivada de la actividad económica y ocupacional de la región. Objetivo: Caracterizar los pacientes con EPOC clínicamente estable de algunos municipios del departamento de Boyacá. Identificar los factores de riesgo. Determinar el tratamiento farmacológico y no farmacológico. Establecer características espirométricas de la población estudiada. Métodos: Estudio transversal descriptivo con muestreo aleatorio probabilístico entre febrero de 2016 a diciembre de 2018. Resultados: Se seleccionaron 248 pacientes con diagnóstico espirométrico confirmado, predominó el sexo masculino 52,8%, la edad promedio fue de 75 años, talla promedio de 1,55cm y peso promedio de 60Kg. Respecto a características demográficas el 88,3% tiene apoyo familiar y el 56,5% alcanzó escolaridad básica primaria. Respecto a la gravedad de la EPOC el 42,3% se clasificó como GOLD 1, 42,7% GOLD 2, 13,3% GOLD 3 y 1,6% GOLD 4; no se establecieron diferencias significativas en los parámetros CVF y VEF1/CVF entre grupos, mientras que VEF1 disminuyó en todos los grupos. Se observó que la medicación que reciben es en forma de monoterapia, terapia doble o terapia triple. Conclusiones: Se evidenció que casi la mitad de los pacientes en los cuatro grupos reportó contaminación del aire en espacios cerrados, aspecto similar a la exposición laboral a material particulado; no se evidenciaron diferencias significativas en los parámetros CVF y relación VEF1/CVF entre los grupos; se observó las medidas no farmacológicas se enfocan en vacunación y oxigenoterapia y las medidas farmacológicas en la administración de monoterapia y terapia triple en mayor proporción; finalmente, alrededor del 20% de los pacientes de cada uno de los grupos no reciben tratamiento farmacológico.


Abstract Introduction: Non-communicable diseases occupy the first place in morbimortality in the department of Boyaca according to recent statistics, in this group of diseases is Chronic Obstructive Pulmonary Disease (COPD) situation probably derived from the economic and occupational activity of the region. Objective: To characterize patients with clinically stable COPD in some municipalities of the Department of Boyaca. To identify risk factors. To determine pharmacological and non-pharmacological treatment. To establish spirometric characteristics of the studied population. Methods: Descriptive cross-sectional study with probabilistic random sampling between February 2016 and December 2018. Results: 248 patients with confirmed spirometric diagnosis were selected, male sex predominated 52.8%, average age was 75 years, average height of 1.55cm and average weight of 60Kg. Regarding demographic characteristics, 88.3% had family support and 56.5% had primary schooling. Regarding COPD severity, 42.3% were classified as GOLD 1, 42.7% GOLD 2, 13.3% GOLD 3 and 1.6% GOLD 4; no significant differences were established in FVC and FEV1/FVC parameters between groups, while FEV1 decreased in all groups. It was observed that the medication they receive is in the form of monotherapy, dual therapy or triple therapy. Conclusions: It was evidenced that almost half of the patients in the 4 groups reported indoor air pollution, an aspect similar to occupational exposure to particulate matter; no significant differences were evidenced in FVC parameters and FEV1/FVC ratio between groups; non-pharmacological measures focus on vaccination and oxygen therapy and pharmacological measures in the administration of monotherapy and triple therapy in greater proportion; finally, about 20% of patients in each of the groups do not receive pharmacological treatment.


Subject(s)
Humans , Male , Female , Spirometry , Therapeutics , Risk Factors , Pulmonary Disease, Chronic Obstructive
20.
Neumol. pediátr. (En línea) ; 17(4): 122-125, 2022. ilus
Article in Spanish | LILACS | ID: biblio-1427368

ABSTRACT

La displasia broncopulmonar (DBP) es una complicación frecuente en los prematuros extremos. La detención de la alveolarización determina menor volumen pulmonar total, el cual se recupera al menos parcialmente en el trayecto de la vida. La vía aérea se ve afectada en su crecimiento en mayor proporción que los alvéolos, y en los pacientes con displasia severa va a existir hasta la etapa adulta una limitación al flujo aéreo debido a su menor calibre. En este artículo, se describirá el origen, hallazgos característicos y evolución de las alteraciones en la función pulmonar, especialmente, en los pacientes con la nueva DBP.


Bronchopulmonary dysplasia (BPD) is a frequent complication in extremely premature infants. The arrest of alveolarization determines a lower total lung volume, which recovers at least partially during life. The airway is affected in its growth to a greater extent than the alveoli, and in patients with severe dysplasia there will be airflow limitation until adulthood due to its smaller caliber. In this article, the origin, characteristic findings, and evolution of changes in lung function will be described, especially in patients with the new BPD.


Subject(s)
Humans , Infant, Newborn , Adult , Bronchopulmonary Dysplasia/physiopathology , Spirometry , Infant, Extremely Premature
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