Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 25
Filter
1.
Mem. Inst. Oswaldo Cruz ; 114: e190260, 2019. tab, graf
Article in English | LILACS | ID: biblio-1040612

ABSTRACT

BACKGROUND Sporotrichosis is a subcutaneous mycosis caused by dimorphic pathogenic fungi belonging to the Sporothrix genus. Pathogenic Sporothrix species typically produce melanin, which is known to be a virulence factor. OBJECTIVES The aim of this study was to perform phenotypic, genotypic, and virulence analyses of two distinct Sporothrix brasiliensis strains isolated from the same lesion on a patient from Rio de Janeiro. METHODS AND FINDINGS Genotypic analyses by partial sequencing of the calmodulin, β-tubulin, and chitin synthase genes, as well as polymerase chain reaction (PCR)-fingerprinting by T3B, M13, and GACA, showed that the isolates were very similar but not identical. Both isolates had similar phenotypic characteristics and effectively produced melanin in their yeast forms, accounting for their ability of causing disease in a murine sporotrichosis model. Remarkably, isolate B was albino in its environmental form but caused more severe disease than the pigmented A isolate. CONCLUSIONS These findings indicate that the patient was infected by two genetically and biologically distinct S. brasiliensis that vary in their production of melanin in their environmental forms. The results underscore the importance of characterizing phenotypically different isolates found in the same clinical specimen or patient.


Subject(s)
Humans , Animals , Mice , Sporotrichosis/pathology , Sporotrichosis/virology , Sporothrix/pathogenicity , Antifungal Agents/pharmacology , Phenotype , Sporothrix/drug effects , Sporothrix/genetics , Virulence , Microbial Sensitivity Tests , Polymerase Chain Reaction , DNA Fingerprinting , Disease Models, Animal , Genotype , Mice, Inbred BALB C
2.
An. bras. dermatol ; 93(5): 743-745, Sept.-Oct. 2018. graf
Article in English | LILACS | ID: biblio-949943

ABSTRACT

Abstract: Atypical mycobacterial infections are caused by mycobacteria other than those from the M. tuberculosis complex and M. leprae. Its incidence has increased progressively, with considerable increase of scientific publications on the subject. Only 10% of the cases present with cutaneous infections, most of them related to surgical interventions and aesthetic procedures. We present a case of mycobacteriosis due to automotive accident that presented a diagnostic challenge due to its clinical presentation with lesions of sporotrichoid progression in the lymphatic system.


Subject(s)
Humans , Male , Adult , Sporotrichosis/pathology , Accidents, Traffic , Skin Diseases, Bacterial/pathology , Mycobacterium Infections, Nontuberculous/pathology , Sporotrichosis/diagnosis , Sporotrichosis/microbiology , Skin Diseases, Bacterial/microbiology , Medical Illustration , Mycobacterium Infections, Nontuberculous/complications
3.
Rev. chil. infectol ; 35(1): 83-87, 2018. graf
Article in Spanish | LILACS | ID: biblio-899780

ABSTRACT

Resumen La esporotricosis es la micosis subcutánea o por implantación más frecuente en México. Se comunica el caso de una esporotricosis cutánea-fija preauricular que simuló una celulitis bacteriana atípica, en una paciente anciana sin antecedente de traumatismo. La biopsia mostró un granuloma supurativo con presencia de levaduras escasas. En el cultivo se identificó Sporothrix schenckii que se confirmó por biología molecular. Se trató con itraconazol obteniéndose una curación clínica y micológica. Se presenta el caso de presentación atípica, proveniente de una zona semidesértica con clima extremo.


Sporotrichosis is the most common subcutaneous or implantation mycosis in Mexico. The case of a preauricular cutaneous-fixed sporotrichosis simulating atypical bacterial cellulitis is reported in an elderly patient with no history of trauma. The biopsy showed a suppurative granuloma with scarce yeast. Sporothrix schenckii was identified in the culture and confirmed by molecular biology. She was treated with itraconazole and a clinical and mycological cure was obtained. The case of atypical presentation is presented, coming from a semi-arid zone with extreme weather.


Subject(s)
Humans , Female , Aged, 80 and over , Sporotrichosis/pathology , Cellulitis/microbiology , Cellulitis/pathology , Ear Diseases/microbiology , Ear Diseases/pathology , Sporotrichosis/drug therapy , Sporothrix/isolation & purification , Biopsy , Treatment Outcome , Itraconazole/therapeutic use , Diagnosis, Differential , Ear Diseases/drug therapy , Antifungal Agents/therapeutic use
4.
Rev. argent. microbiol ; 48(3): 196-199, set. 2016. ilus, tab
Article in Spanish | LILACS | ID: biblio-843163

ABSTRACT

Introducción: La esporotricosis es una infección causada por especies pertenecientes al complejo Sporothrix schenckii. Dependiendo de la especie, estos organismos pueden tener virulencia y formas clínicas diferentes. Objetivo: Verificar la virulencia de una cepa de Sporothrix globosa en un modelo murino usando 2 concentraciones de inóculo, en aplicación intraperitoneal o subcutánea. Materiales y métodos: Estudio experimental no aleatorizado en murinos inoculados con una cepa de S. globosa (CBS 14.076 M), por vía intraperitoneal y subcutánea, a 0,5 y 4 de concentración McFarland. Se utilizaron 18 roedores CF-1 (ISP, Santiago, Chile). Resultados: La cepa estudiada no provocó enfermedad ni lesiones, todos los animales sobrevivieron, no hubo desarrollo de hongos en el cultivo de tejidos y el análisis histopatológico de órganos no mostró alteraciones sugerentes de infección. Conclusiones: La cepa de S. globosa estudiada no presentó virulencia en modelos murinos y no provocó enfermedad al ser inoculada a concentración McFarland 0,5 y 4, tanto por vía intraperitoneal como subcutánea.


Introduction: The sporothricosis disease is an infection caused by species included in Sporothrix schenkii complex. Objective: Verify the virulence of a strain of S. globosa using two different concentrations of inoculum by intraperitoneally and subcutaneously, into a mouse model. Materials and methods: Nonrandomized pilot study, in murine inoculated with a strain of S. globosa (CBS 14.076 M) by intraperitoneally and subcutaneously with inoculum concentrations of 0.5 and 4 McFarland. For this purpose 18 rodents CF-1 (ISP, Santiago, Chile) were used. Results: The studied strain did not induce illness or injury on animals, they all survived and neither the tissue culture nor the histopathological analysis showed fungal growth or suggestive infection by organ abnormalities. Conclusions: The S. globosa strain did not present any virulence enough to cause disease at 0.5 and 4.0 McFarland concentration inoculum when inoculated in both intraperitoneally and subcutaneously, in murine models.


Subject(s)
Animals , Rats , Sporotrichosis/microbiology , Sporothrix/isolation & purification , Virulence , Sporotrichosis/pathology
5.
Rev. chil. infectol ; 33(3): 315-321, jun. 2016. ilus
Article in Spanish | LILACS | ID: lil-791026

ABSTRACT

Introducción: La esporotricosis es una afección endémica en numerosos países latinoamericanos y en el resto del mundo. En Perú se concentra en regiones con clima cálido y húmedo, siendo poco conocida en el resto del país. Objetivo: Describir las características epidemiológicas, clínicas y de laboratorio de esporotricosis en pacientes de un hospital de tercer nivel en Lima-Perú, entre los años 1991 y 2014.Método: Estudio descriptivo, retrospectivo, tipo serie de casos. Resultados: Se incluyeron 94 pacientes, la mayoría de los cuales fueron adultos del sexo masculino. Los lugares de adquisición más frecuentes fueron Cajamarca, Apurímac, y Amazonas. Las formas linfo-cutánea y cutánea fija fueron observadas con mayor frecuencia en adultos y, en especial de localización en los miembros superiores. Las localizaciones en la cabeza y el cuello fueron más frecuentes en niños. Co-morbilidades estuvieron presentes en 15% de pacientes, en particular en aquellos con la forma cutánea diseminada. El 78% de los cultivos procedentes de lesiones cutáneas fueron positivos dentro de siete días, y el tiempo de positividad fue mayor en cultivos de biopsia que en las muestras por raspado-aspirado. Conclusiones: Esporotricosis fue adquirida mayoritariamente en zonas del Perú con pobreza extrema. Las características clínicas, epidemiológicas y de laboratorio no difieren de las reportadas en otros estudios. El tiempo de positividad de los cultivos varía según tipo de muestra, lo que deberá ser mejor evaluado en estudios futuros.


Background: Sporothricosis is endemic in numerous Latin American countries and the rest of the world. In Peru is concentrated in regions with warm and humid climate being little known in the rest of the country. Aim: To describe the epidemiological, clinical and laboratory characteristics of patients diagnosed of sporotrichosis in a tertiary-care level hospital in Lima, Peru from 1991 to 2014. Methods: This was a retrospective, case series. Results: Ninety four patients were involved; most of them were male adults. This condition was acquired more frequently in Cajamarca, Apurímac, and Amazonas. Fixed and lymphocutaneous form were the most frequent forms of presentation in adults and were mostly distributed in upper limbs. Lesions located in head and neck were most frequent in children. Comorbidities were present in 15% of patients and were more frequent in those who presented disseminated cutaneous form. Seventy eight percent of cultures from skin lesions were positive within 7 days. The time to positivity of cultures was longer if the sample came from skin biopsies than skin scraping or skin aspiration. Conclusions: Most cases of sporotrichosis were acquired in areas of extreme poverty in Peru. The clinical, epidemiological and laboratory findings were similar to those reported elsewhere. The time to positivity of cultures varies based on the type of skin sample. This finding needs to be further evaluated in studies with an increased number of cases.


Subject(s)
Humans , Male , Female , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Young Adult , Sporotrichosis/pathology , Sporotrichosis/epidemiology , Peru/epidemiology , Socioeconomic Factors , Sporotrichosis/drug therapy , Sporothrix/isolation & purification , Time Factors , Biopsy , Poverty Areas , Retrospective Studies , Tertiary Care Centers/statistics & numerical data , Antifungal Agents/therapeutic use
6.
An. bras. dermatol ; 90(3,supl.1): 84-87, May-June 2015. ilus
Article in English | LILACS | ID: lil-755747

ABSTRACT

Abstract

Sporotrichosis is the most common subcutaneous mycosis. It is caused by the dimorphic fungus Sporothrix schenckii, and the infection is usually acquired by traumatic inoculation. We describe a case of sporotrichosis in an uncommon location with an unusual mode of transmission. A 49-year-old female patient who lived in an urban area of Rio de Janeiro presented with involvement of the left ear. No history of contact with soil, plants or animals was elicited. The suspected source of infection was a pair of handmade wooden earrings. The delay in the diagnosis and treatment resulted in higher morbidity, unsightly scarring and loss of ear lobe.

.


Subject(s)
Female , Humans , Middle Aged , Ear Auricle/pathology , Sporotrichosis/pathology , Delayed Diagnosis , Ear Auricle/microbiology , Itraconazole/therapeutic use , Jewelry/microbiology , Sporotrichosis/transmission , Wood/microbiology
7.
Rev. chil. infectol ; 32(2): 234-237, abr. 2015. ilus
Article in Spanish | LILACS | ID: lil-747527

ABSTRACT

Tuberculosis remains a major global health problem. Cutaneous involvement is a rare manifestation of tuberculosis infection. Sporotrichoid clinical pattern consists of a linear arrangement of nodules along the lymphatic vessels. It is often seen in sporotrichosis. Few cases have been reported of cutaneous tuberculosis presenting as a sporotrichoid clinical pattern. We describe a 84-year-old female with ulcerative nodules on upper extremity caused by Mycobacterium tuberculosis, emphasizing the importance of considering cutaneous tuberculosis in the differential diagnosis of sporotrichoid lesions.


En la actualidad, la tuberculosis sigue siendo un problema de salud pública en el mundo. El compromiso cutáneo es una manifestación poco frecuente de la infección por Mycobacterium tuberculosis. El patrón esporotricoide se refiere a la disposición lineal de los nódulos cutáneos siguiendo el trayecto de los vasos linfáticos, forma de presentación característica de la esporotricosis, de ahí su nombre. Muy pocos casos han sido reportados sobre tuberculosis cutánea con patrón esporotricoide. Se presenta el caso clínico de una mujer de 84 años con nódulos ulcerativos de disposición lineal en miembro superior causados por Mycobacterium tuberculosis, destacando la importancia de incluir a la tuberculosis cutánea en el diagnóstico diferencial de lesiones con patrón esporotricoide.


Subject(s)
Aged, 80 and over , Female , Humans , Sporotrichosis/pathology , Tuberculosis, Cutaneous/pathology , Diagnosis, Differential , Immunocompromised Host , Mycobacterium tuberculosis/isolation & purification
8.
Dermatol. peru ; 24(2): 123-127, abr.-jun. 2014. ilus
Article in Spanish | LILACS, LIPECS | ID: lil-765237

ABSTRACT

La esporotricosis es una micosis profunda y crónica que afecta la piel y tejido linfático, causada por el hongo Sporothrix schenckii. Es la micosis subcutánea más frecuente en el Perú. Los sitios comúnmente afectados son las extremidades superiores y la cara; esta última localización es la más frecuente en niños. Su diversidad clínica plantea un desafío diagnóstico. Se presentan cuatro casos clínicos de esporotricosis facial en pacientes pediátricos provenientes de Otuzco (La Libertad), un área endémica del norte del país. El diagnóstico se confirmó con cultivo en el que se aisló S. schenckii. El tratamiento de elección fue yoduro de potasio por su coste beneficio. Por su polimorfismo, la esporotricosis, debe ser incluida en el diagnóstico diferencial de las dermatosis faciales crónicas en niños.


Sporotrichosis is a deep and chronic mycosis that affects the skin and lymph tissue, caused by the fungus Sporothrix schenckii. It is the most common subcutaneous mycosis in Peru. Commonly affected sites are the upper extremities and face, the latter being the most common location in children. His clinical diversity poses a diagnostic challenge. We present four cases of facial sporotrichosis in pediatric patients from Otuzco (La Libertad), an endemic area in the north. The diagnosis was confirmed by culture in which S. schencki i was isolated. The treatment of choice was potassium iodide at cost benefit. On the polymorphism, sporotrichosis, should be included in the differential diagnosis of chronic facial dermatosis in children.


Subject(s)
Humans , Sporotrichosis , Sporotrichosis/diagnosis , Sporotrichosis/pathology , Sporotrichosis/therapy , Medical Illustration
9.
Rio de Janeiro; s.n; 2013. xviii,88 p. ilus, graf, tab.
Thesis in Portuguese | LILACS | ID: lil-736938

ABSTRACT

A ocorrência de formas graves de esporotricose felina, aliada a lesões sem granulomas e ricas em estruturas leveduriformes, evidencia a suscetibilidade destes animais para a doença e enfatiza a importância do estudo da sua patogenia. O objetivo deste estudo foi descrever o processo inflamatório e a carga fúngica das lesões em diferentes apresentações clínicas, e sua relação com o perfil de leucócitos no sangue periférico de gatos com esporotricose por meio da técnica de citometria de fluxo (CF) e com a infecção pelo Vírus da Imunodeficiência Felina (FIV) e/ou pelo Vírus da Leucemia Felina (FeLV). Gatos com lesões cutâneas com isolamento de Sporothrix sp. foram incluídos no estudo, separados nos grupos L1, L2 e L3 (lesões em um, dois e três ou mais locais, respectivamente) e submetidos a coleta de sangue e de fragmentos de lesão. O estado geral dos animais foi classificado como bom, regular ou ruim. Ao exame histopatológico, as lesões foram agrupadas de acordo com o processo inflamatório (granulomatoso ou inespecífico), grau de ativação de fagócitos predominantes nos granulomas (macrófagos ou células epitelióides), organização do granuloma (bem formado ou mal formado) e intensidade dos tipos celulares no infiltrado. A carga fúngica foi verificada pelas técnicas de impregnação pela prata de Grocott (IPG) e imuno-histoquímica (IHQ). [...] O processo inflamatório granulomatoso supurativo (PIGS) foi observado em 99 casos. A maioria das lesões, sobretudo no grupo L3, apresentavam granulomas mal formados (pvalor= 0,032) e com predomínio de macrófagos (p-valor=0,010)...


The occurrence of severe forms of feline sporotrichosis, along with lesions without granulomasand rich in yeast-like forms, demonstrate the susceptibility of these animals to the disease andemphasizes the importance of the study of its pathogenesis. The aim of this study was to describethe inflammatory changes and fungal load at different clinical presentations and its relationshipwith the profile of leukocytes in peripheral blood of cats with sporotrichosis by means of flowcytometry (FC) technique and with Feline Immunodeficiency Virus (FIV) and / or FelineLeukemia Virus (FeLV). Cats presenting cutaneous lesions with isolation of Sporothrix sp. inculture were included. They were separated in groups L1, L2 and L3 (lesions in one, two andthree or more sites, respectively) and were subjected to blood sample collection and to biopsy ofthe lesion. The general condition of the animals was classified as good, fair or poor.Histologically, the lesions were described according to the inflammatory process (granulomatousor nonspecific), degree of activation of predominant phagocytes within the granulomas(macrophages or epithelioid cells), granulomas organization (well-formed or poorly formed) andintensity of cell types within the inflammation. The fungal load was assessed by Grocott silverstain (GSS) technique and immunohistochemistry (IHC). [...] Onehundred and one animals were included: 20 in group L1, 22 in group L2 and 59 in group L3.Histologically, 99 lesions showed suppurative granulomatous inflammation (SGI). Most lesions,specially in the group L3, showed poorly formed granulomas (p-value=0.032) and predominantlymacrophages (p-value=0.010)...


Subject(s)
Humans , Cats , Sporotrichosis/diagnosis , Sporotrichosis/pathology , Flow Cytometry , Immunity, Mucosal
10.
An. bras. dermatol ; 86(6): 1217-1219, nov.-dez. 2011. ilus
Article in Portuguese | LILACS | ID: lil-610434

ABSTRACT

Esporotricose é uma infecção fúngica subcutânea, adquirida por inoculação direta, causada pelo Sporothrix schenckii. Embora a apresentação clássica linfocutânea represente a maioria dos casos, as formas clínicas atípicas e graves têm aumentado em ocorrência. Esporotricose sistêmica e esporotricose cutânea disseminada são variantes raras, usualmente associadas à imunodeficiência celular ou a estados debilitantes. Relatamos o primeiro caso na literatura de lesões molusco-símiles em esporotricose cutaneomucosa múltipla. Os exames micológico direto e histopatológico apresentavam-se ricos em células leveduriformes.


Sporotrichosis is a subcutaneous fungal infection caused by Sporothrix schenckii and acquired by direct inoculation. Although the majority of cases consist of the classic lymphocutaneous presentation, the frequency of atypical and severe clinical forms of the disease has increased progressively. Systemic and disseminated cutaneous sporotrichosis constitute rare variants and such cases are generally associated with cellular immunodeficiency or debilitated states. The present paper describes the first published case of molluscum-like lesions in disseminated mucocutaneous sporotrichosis. Direct mycological examination and histopathology revealed numerous yeast cells.


Subject(s)
Humans , Male , Middle Aged , Sporothrix , Sporotrichosis/microbiology , Sporotrichosis/pathology , Brazil , Fatal Outcome , Skin/pathology , Sporotrichosis/therapy
11.
Rev. Soc. Bras. Med. Trop ; 42(6): 706-710, Dec. 2009. tab
Article in Portuguese | LILACS | ID: lil-539522

ABSTRACT

O estudo objetivou avaliar a atividade in vivo do itraconazol e terbinafina no tratamento da esporotricose cutânea experimental. Foram utilizados 80 ratos Wistar divididos em quatro grupos (TERB20, TERB30, ITRA e CONT) inoculados no coxim plantar esquerdo com 0,2ml de solução contendo 2x103 células de Sporothrix schenckii/ml e tratados com terbinafina (20 e 30mg/kg), itraconazol (10mg/kg) e placebo durante 13 semanas. As lesões do sítio de inoculação foram avaliadas e mensuradas semanalmente, assim como a disseminação das mesmas. Após foi realizada análise micológica e histopatológica. Os resultados demonstraram que os animais do grupo ITRA diferiram estatisticamente em todos os parâmetros avaliados em relação ao CONT. Em relação à terbinafina, não houve diferenças estatísticas entre os grupos tratados e controle. Pode-se confirmar a boa atividade do itraconazol no tratamento da esporotricose e a pouca eficácia da terbinafina nas doses utilizadas, sendo necessários mais estudos com este antifúngico.


The aim of this study was to evaluate the in vivo activity of itraconazole and terbinafine for treating experimental cutaneous sporotrichosis. Eighty Wistar rats were used, divided into four groups (TERB20, TERB30, ITRA and CONT). They were inoculated in the left plantar pad with 0.2 ml of solution containing 2x10³ cell/ml of Sporothrix schenckii and treated with terbinafine (20 and 30 mg/kg), itraconazole (10 mg/kg) or placebo for 13 weeks. The lesions at the inoculation site were evaluated and measured weekly, along with their dissemination. Mycological and histopathological analyses were performed subsequently. The results showed that the animals in the ITRA group differed statistically in all parameters evaluated, in relation to CONT. For terbinafine, there were no statistical differences between the treated and control groups. It could be confirmed that itraconazole presented good activity for treating sporotrichosis, while terbinafine was ineffective for this disease at the doses used. However, more studies on the latter antifungal agent are needed.


Subject(s)
Animals , Male , Rats , Antifungal Agents/therapeutic use , Itraconazole/therapeutic use , Naphthalenes/therapeutic use , Sporotrichosis/drug therapy , Drug Evaluation, Preclinical , Rats, Wistar , Sporotrichosis/pathology
12.
Arch. argent. dermatol ; 59(5): 211-215, 2009. ilus
Article in Spanish | LILACS | ID: lil-626083

ABSTRACT

La esporotricosis es una infección micótica profunda de la piel, causada por un hongo dimorfo, es Sporothrix schenckii, que se encuentra en forma saprófita en la naturaleza. Tiene distribución mundial, predominantemente en regiones tropicales y subtropicales. La infección usualmente se produce por inoculación traumática. Las formas de presentación clínicas se clasifican en : cutáneas y extracutáneas. El diagnóstico definitivo se establece por cultivo. El tratamiento de elección es la solución satura de ioduro de potasio; otras alternativas son los derivados asólicos, la anfotericina B y el uso de terapia térmica. Presentamos el caso de un paciente de sexo masculino, de 30 años de edad, oriundo de Bolivia, trabajador rural, que presenta lesiones vegetantes en pie izquierdo de un año de evolución. En el cultivo micológico fue identificado el Sporothrix schenckii, observándose una excelente respuesta al tratamiento con itraconazol.


Subject(s)
Humans , Male , Adult , Sporotrichosis/diagnosis , Sporotrichosis/microbiology , Sporotrichosis/pathology , Antifungal Agents/therapeutic use , Itraconazole/therapeutic use , Skin/pathology
14.
Rev. Soc. Bras. Med. Trop ; 35(6): 655-659, nov.-dez. 2002. ilus, tab
Article in English | LILACS | ID: lil-340067

ABSTRACT

We describe a case report of disseminated cutaneous sporotrichosis as the initial presentation of AIDS in a 24-year-old HIV-positive male patient. He presented multiple ulcerated skin lesions distributed over the face, thorax, legs and arms. Biopsy of one of the cutaneous lesions was suggestive of sporotrichosis and culture isolated Sporothrix schenckii. Itraconazole was started and the lesions progressively resolved after 15 days of medication. The patient was discharged with this medication but he did not return for follow-up. He died three months later in another hospital. Therapy of sporotrichosis in HIV-infected patients remains unclear and the response to therapy is variable. Itraconazole is highly concentrated in the skin and is one of the options for treatment of disseminated sporotrichosis


Subject(s)
Adult , Humans , Male , AIDS-Related Opportunistic Infections/pathology , Sporothrix/isolation & purification , Sporotrichosis/pathology , AIDS-Related Opportunistic Infections/drug therapy , AIDS-Related Opportunistic Infections/microbiology , Antifungal Agents/therapeutic use , Fatal Outcome , Itraconazole/therapeutic use , Sporotrichosis/drug therapy
15.
HU rev ; 25/26(3/1): 203-20, set. 1999-abr. 2000. ilus
Article in Portuguese | LILACS | ID: lil-296293
17.
Arch. argent. dermatol ; 46(4): 175-82, jul.-ago. 1996. ilus
Article in Spanish | LILACS | ID: lil-177421

ABSTRACT

Se realiza una descripción histopatológica de las micosis profundas de mayor frecuencia en el Noroeste Argentino, con una pequeña referencia clínica y del medio ambiente en que se desarrollan las mismas


Subject(s)
Humans , Actinomycosis/pathology , Blastomycosis/pathology , Chromoblastomycosis/pathology , Histoplasmosis/pathology , Mycetoma/pathology , Mycoses/pathology , Paracoccidioidomycosis/pathology , Sporotrichosis/pathology , Mycetoma/diagnosis , Mycetoma/etiology , Mycoses/classification , Mycoses/complications , Nocardia/pathogenicity
18.
Rev. bras. oftalmol ; 54(12): 31-5, dez. 1995. ilus
Article in Portuguese | LILACS | ID: lil-280026

ABSTRACT

Os autores relatam o isolamento de Sporothrix schenckii no humor aquoso de uma paciente de 12 anos, portadora de esporotricase cutânea e extracutânea sistêemico. A dificuldade de tratamento dessa forma de apresentaçäo da micose é discutida e comparada com a literatura, apesar dos dados serem escassos.


Subject(s)
Humans , Female , Child , Aqueous Humor/microbiology , Aqueous Humor/parasitology , Sporothrix/isolation & purification , Sporothrix/pathogenicity , Sporotrichosis/parasitology , Sporotrichosis/pathology , Uveitis, Anterior/complications , Uveitis, Anterior/pathology , Uveitis, Anterior
19.
Dermatol. rev. mex ; 39(1): 34-6, ene.-feb. 1995. ilus
Article in Spanish | LILACS | ID: lil-151320

ABSTRACT

Paciente con esporotricosis sistémica y diabetes mellitus con una historia negativa de evento traumático, previo a la aparición de las lesiones. Estudio histopatológico con una gran cantidad de elementos fúngicos. El paciente empeoró progresivamente hasta su fallecimiento, a pesar de tratamiento con anfotericina-B


Subject(s)
Middle Aged , Humans , Male , Diabetes Mellitus/complications , Sporotrichosis/mortality , Sporotrichosis/pathology
20.
Rev. argent. micol ; 15(2): 7-11, mayo-ago. 1992. ilus
Article in Spanish | LILACS | ID: lil-122880

ABSTRACT

Ratas endocriadas se infectaron por vía intraperitoneal y en la cola con una suspensión de conidios de Sporothrix schenckii. Los frotis coloreados con May Grunwald-Giemsa y Gram Nicolle, así como los cultivos de macerados de los órganos que se biopsiaron: hígado, bazo, pulmón y glándula suprarrenal y de la cola manifestaron a los l5 días de inoculación una diseminación del hongo; no así a los 30 días de infección, excepto el material correspondiente a la cola que presentó en ese tiempo elementos de S.schenckii. Los estudios inmunológicos realizados permitieron la estandarización del exoantígeno preparado, se detectaron anticuerpos en los sueros de las ratas a los 15 y 30 días posteriores a la inoculación. Las intradermorreacciones realizadas en los animales provocaron una buena respuesta frente al exoantígeno preparado. De esta forma, se comprueba que la rata es un animal adecuado para la infección experimental y la estandarización de antígenos de S.schenckii


Subject(s)
Animals , Female , Rats , Allergy and Immunology , Antigens, Fungal/isolation & purification , Antigens, Fungal/immunology , Sporothrix/isolation & purification , Sporotrichosis/diagnosis , Sporotrichosis/immunology , Sporotrichosis/pathology , Rats, Inbred Strains/immunology , Research
SELECTION OF CITATIONS
SEARCH DETAIL