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1.
Chinese Medical Journal ; (24): 439-447, 2020.
Article in English | WPRIM | ID: wpr-877917

ABSTRACT

BACKGROUND@#Texture analysis (TA) can quantify intra-tumor heterogeneity using standard medical images. The present study aimed to assess the application of positron emission tomography (PET) TA in the differential diagnosis of gastric cancer and gastric lymphoma.@*METHODS@#The pre-treatment PET images of 79 patients (45 gastric cancer, 34 gastric lymphoma) between January 2013 and February 2018 were retrospectively reviewed. Standard uptake values (SUVs), first-order texture features, and second-order texture features of the grey-level co-occurrence matrix (GLCM) were analyzed. The differences in features among different groups were analyzed by the two-way Mann-Whitney test, and receiver operating characteristic (ROC) analysis was used to estimate the diagnostic efficacy.@*RESULTS@#InertiaGLCM was significantly lower in gastric cancer than that in gastric lymphoma (4975.61 vs. 11,425.30, z = -3.238, P = 0.001), and it was found to be the most discriminating texture feature in differentiating gastric lymphoma and gastric cancer. The area under the curve (AUC) of inertiaGLCM was higher than the AUCs of SUVmax and SUVmean (0.714 vs. 0.649 and 0.666, respectively). SUVmax and SUVmean were significantly lower in low-grade gastric lymphoma than those in high grade gastric lymphoma (3.30 vs. 11.80, 2.40 vs. 7.50, z = -2.792 and -3.007, P = 0.005 and 0.003, respectively). SUVs and first-order grey-level intensity features were not significantly different between low-grade gastric lymphoma and gastric cancer. EntropyGLCM12 was significantly lower in low-grade gastric lymphoma than that in gastric cancer (6.95 vs. 9.14, z = -2.542, P = 0.011) and had an AUC of 0.770 in the ROC analysis of differentiating low-grade gastric lymphoma and gastric cancer.@*CONCLUSIONS@#InertiaGLCM and entropyGLCM were the most discriminating features in differentiating gastric lymphoma from gastric cancer and low-grade gastric lymphoma from gastric cancer, respectively. PET TA can improve the differential diagnosis of gastric neoplasms, especially in tumors with similar degrees of fluorodeoxyglucose uptake.


Subject(s)
Fluorodeoxyglucose F18 , Humans , Lymphoma, Non-Hodgkin , Positron Emission Tomography Computed Tomography , Positron-Emission Tomography , ROC Curve , Radiopharmaceuticals , Retrospective Studies , Stomach Neoplasms/diagnostic imaging
2.
Braz. j. infect. dis ; 23(6): 451-461, Nov.-Dec. 2019. tab, graf
Article in English | LILACS | ID: biblio-1089312

ABSTRACT

ABSTRACT Background: Papiliotrema laurentii is one of several non-neoformans cryptococci that have rarely been associated with human infection, since it was previously considered saprophyte and thought to be non-pathogenic to humans. Nevertheless, increasing number of reports of human infection have emerged in recent years, mostly in oncologic patients. Aim: To report a case of a female patient with pyloric obstructive cancer with a catheter-related Papiliotrema laurentii blood stream infection and systematically review the available evidence on P. laurentii infection in humans. Methods: Retrieval of studies was based on Medical Subject Headings and Health Sciences Descriptors, which were combined using Boolean operators. Searches were run on the electronic databases Scopus, Web of Science, MEDLINE (PubMed), BIREME (Biblioteca Regional de Medicina), LILACS (Latin American and Caribbean Health Sciences Literature), Cochrane Library for Systematic Reviews and Opengray.eu. There was no language or date of publication restrictions. The reference lists of the studies retrieved were searched manually. Results: The search strategy retrieved 1703 references. In the final analysis, 31 references were included, with the description of 35 cases. Every patient but one had a previous co-morbidity - 48.4 % of patients had a neoplasm. Amphotericin B was the most used treatment and only a single case of resistance to it was reported. Most patients were cured of the infection. Conclusion: P. laurentii infection in humans is usually associated to neoplasia and multiple co-morbidities, and amphotericin B seems to be a reliable agent for treatment.


Subject(s)
Humans , Female , Aged , Stomach Neoplasms/diagnostic imaging , Catheter-Related Infections/diagnostic imaging , Stomach Neoplasms/microbiology , Stomach Neoplasms/therapy , Biopsy , Vancomycin/therapeutic use , Tomography, X-Ray Computed , Fluconazole/therapeutic use , Amphotericin B/therapeutic use , Bacteremia/microbiology , Cryptococcus/isolation & purification , Catheter-Related Infections/etiology , Catheter-Related Infections/microbiology , Catheter-Related Infections/drug therapy , Piperacillin, Tazobactam Drug Combination/therapeutic use , Anti-Bacterial Agents/therapeutic use
3.
Rev. Assoc. Med. Bras. (1992) ; 64(11): 1002-1006, Nov. 2018. tab, graf
Article in English | LILACS | ID: biblio-976793

ABSTRACT

SUMMARY OBJECTIVE: This study retrospectively reviewed 46 cases of gastric gastrointestinal stromal tumors treated by endoluminal endoscopic full-thickness resection (EFR) microsurgery in our gastrointestinal endoscopy center. We aimed to evaluate the EFR for the treatment of gastric gastrointestinal stromal tumors originating from the muscularis propria. METHODS: A total of 46 patients with gastric gastrointestinal stromal tumors originated from the muscularis propria layer from January 2012 to June 2015 were treated with EFR. The patients were followed up with gastroscope and computed tomography (CT) for evaluation of therapeutic effect and safety. RESULTS: EFR was successfully accomplished to remove all tumors in 46 patients. The mean procedure time was 82.5±39.8min (56-188min). Except in 3 leiomyomas, pathological examination confirmed gastrointestinal stromal tumor (GIST) in 43 cases. None of the patients had occurred bleeding, peritonitis and other complications after EFR. Thereafter, all patients were followed up with gastro-scope after 1, 6,12 months. CONCLUSIONS: EFR is effective and safe for patients with gastric gastrointestinal stromal tumors originated from muscularis propria layer and has the advantage of less invasive treatment and higher tumor resection rate. It should be considered for further application.


RESUMO OBJETIVO: Este estudo revisou retrospectivamente 46 casos de tumores gástricos estromáticos gastrointestinais tratados por microcirurgia endoluminal endoscópica de ressecção completa (EFR) em nosso centro de endoscopia gastrointestinal. Pretendemos avaliar a EFR para o tratamento de tumores gastrointestinais estromáticos originários da muscularis própria. MÉTODOS: Um total de 46 pacientes com tumores gástricos estromáticos gastrointestinais originários da camada muscular própria, de janeiro de 2012 a junho de 2015, foi tratado com EFR. Os pacientes foram acompanhados com gastroscópio e tomografia computadorizada (TC) para avaliação de efeitos terapêuticos e segurança. RESULTADOS: A EFR foi realizada com sucesso para remover todos os tumores em 46 pacientes. O tempo médio de procedimento foi de 82,5±39,8 min (56-188 min). Exceto em três leiomiomas, exame patológico confirmou tumor estromal gastrointestinal (Gist) em 43 casos. Em nenhum paciente ocorreu sangramento, peritonite e outras complicações após EFR. Posteriormente, todos os pacientes foram acompanhados com gastroscópio após um, seis e 12 meses. CONCLUSÕES: A EFR é eficaz e segura para pacientes com tumores gastrointestinais originários da camada muscular própria e tem a vantagem de ser um tratamento menos invasivo e com maior taxa de ressecção tumoral. Deve ser considerada para posterior aplicação.


Subject(s)
Humans , Male , Female , Adult , Aged , Young Adult , Stomach Neoplasms/surgery , Gastrointestinal Stromal Tumors/surgery , Endoscopic Mucosal Resection/methods , Gastrectomy/methods , Gastric Mucosa/surgery , Leiomyoma/surgery , Stomach Neoplasms/diagnostic imaging , Retrospective Studies , Treatment Outcome , Gastrointestinal Stromal Tumors/diagnostic imaging , Gastric Mucosa/pathology , Leiomyoma/pathology , Middle Aged
4.
Rev. cuba. invest. bioméd ; 37(1): 32-46, ene.-mar. 2018. tab
Article in Spanish | LILACS, CUMED | ID: biblio-991089

ABSTRACT

Fundamento: el cáncer gástrico constituye la segunda causa de muerte por cáncer en el mundo. Objetivo: validar el ultrasonido hidrogástrico en el diagnóstico del cáncer gástrico avanzado. Métodos: el ultrasonido hidrogástrico fue realizado por dos observadores independientes a 100 pacientes, 30 con cáncer gástrico avanzado, confirmados por endoscopia y biopsia; y 70 pacientes sin cáncer gástrico. Resultados: por regresión logística se determinó que el engrosamiento de la pared gástrica fue el único signo con valor como predictor de la presencia de CG. La sensibilidad, especificidad, certeza, valor predictivo positivo y valor predictivo negativo del ultrasonido hidrogástrico fueron de 83,3 por ciento; 90, por ciento; 88,0 por ciento; 78,1 por ciento y 92,6 por ciento respectivamente. Conclusiones: el ultrasonido hidrogástrico es una modalidad diagnostica útil en el diagnóstico del cáncer gástrico avanzado(AU)


Background: gastric cancer still remains one of the most common malignancies worldwide. Objective: to validate the Conventional hydrogastric ultrasound in the diagnosis of the advanced gastric cancer. Methods: the hydrogastric ultrasound was carried out by two independent observers 30 with cancer patients with advanced gastric cancer, confirmed by endoscopy and biopsy; and 70 patients without gastric cancer. Results: for logistical regression it was determined that the thickening of the gastric wall was the only sign with value like predictor of the presence of advancedgastric cancer. The sensibility, specificity, certainty, value positive predictive and value negative predictive of the hydrogastric ultrasound in the diagnosis of gastric cancer were of 83,3 percent; 90;0 percent; 88,0 percent; 78,1 percent y 92,6 percent respectively. Conclusions: the Hydrogastric ultrasound is a diagnostic modality useful in the diagnosis of the advanced gastric cancer(AU)


Subject(s)
Humans , Male , Female , Stomach Neoplasms/diagnostic imaging , Ultrasonics/methods , Abdominal Wall/diagnostic imaging , Validation Study
5.
Rev. medica electron ; 39(3): 507-518, may.-jun. 2017.
Article in Spanish | LILACS, CUMED | ID: biblio-902190

ABSTRACT

Introducción: el cáncer gástrico avanzado constituye la segunda causa de muerte por tumores malignos en el mundo. En los últimos cinco años en la provincia de Matanzas existe un incremento de esta patología. Objetivo: determinar el comportamiento clínico epidemiológico del cáncer gástrico avanzado diagnosticado por videoendoscopía, en el departamento de Gastroenterología del Hospital Universitario "Comandante Faustino Pérez Hernández", de Matanzas en el período de enero del 2014 a enero del 2016. Materiales y Métodos: se realizó un estudio observacional, descriptivo y prospectivo en el Departamento de Gastroenterología del Hospital Universitario "Comandante Faustino Pérez Hernández", de Matanzas en el período de enero del 2014 a enero del 2016. El universo los 28 pacientes que presentaron cáncer gástrico avanzado por diagnóstico endoscópico e histológico. Resultados: el grupo de edad más afectado correspondió a los pacientes con 60 años de edad o más (67,9 %). El sexo masculino predominó, un 57,1 %. Los factores de riesgo de mayor incidencia fueron la dieta inadecuada (65 %) y el hábito de fumar (42,9 %). Las manifestaciones clínicas más relevantes fueron la pérdida de peso, la astenia y la acidez. La variedad histica que predominó fue el adenocarcinoma de tipo intestinal y el antro gástrico resultó ser la localización más frecuente. La mayoría de los pacientes tuvieron positivos el test de ureasa para la infección por Helicobacter pylori. (60,7 %). Conclusiones: la infección por Helicobacter pylori constituye una de las principales causas de cáncer gástrico. El diagnóstico y tratamiento precoz de la infección contribuirán a disminuir su incidencia (AU).


Introduction: the advanced gastric cancer is the second reason of death due to malignant cancer in the world. There it is a surge of this disease in the last five years in the province of Matanzas. Objective: to determine the clinical-epidemiologic behavior of advanced gastric cancer diagnosed by video-endoscopy in the Department of Gastroenterology of the Teaching Hospital "Comandante Faustino Pérez Hernández", of Matanzas, in the period from January 2014 to January 2016. Materials and Methods: an observational, descriptive and prospective study of the department of Gastroenterology of the Teaching Hospital "Comandante Faustino Pérez Hernández", of Matanzas, was carried in the period from January 2014 to January 2016. The universe were 28 patients who had advanced gastric cancer according to the endoscopic and histological diagnosis. Outcomes: the most affected age group was the one of the patients aged 60 years and more (67,9 %).The male sex predominated, with 57,1 %. The risk factors with higher incidence were an inadequate diet (65 %) and smoking (42,9 %). The most relevant clinical manifestations were weight loss, asthenia and heartburn. The predominating histological variety was the intestinal type adenocarcinoma and the gastric antrum was the most frequent location. Most of the patients were positive to the urease test for helicobacter pylori (60,7 %). Conclusions: the infection by Helicobacter pylori is one of the main causes of gastric cancer. The precocious diagnosis and treatment of the infection will favor the reduction of its incidence (AU).


Subject(s)
Humans , Male , Female , Stomach Neoplasms/diagnostic imaging , Capsule Endoscopy/methods , Stomach Neoplasms/diagnosis , Stomach Neoplasms/epidemiology , Helicobacter pylori/pathogenicity , Observational Studies as Topic , Neoplasms/complications , Neoplasms/diagnosis , Neoplasms/epidemiology
6.
Rev. méd. Chile ; 145(4): 533-537, abr. 2017. ilus, tab
Article in Spanish | LILACS | ID: biblio-902507

ABSTRACT

Carney described a disorder characterized by the presence of several uncommon tumors which were pulmonary chondromas, gastric sarcomas and extra-adrenal paragangliomas. We report a 14 year-old girl in whom multiple gastric tumors were discovered during a study of an iron deficiency anemia and was subjected to a partial gastrectomy. At 25 years of age, she developed several pulmonary chondromas and at 33 years, a mediastinal tumor with features of an extra-adrenal paraganglioma was found. At 35 years of age, a total gastrectomy was performed to remove a gastrointestinal stromal tumor with excision of peritoneal and lymph node metastasis. One year later, the patient died due to liver failure secondary to liver metastases.


Subject(s)
Humans , Female , Adolescent , Stomach Neoplasms/diagnosis , Chondroma/diagnosis , Paraganglioma, Extra-Adrenal/diagnosis , Leiomyosarcoma/diagnosis , Lung Neoplasms/diagnosis , Stomach Neoplasms/surgery , Stomach Neoplasms/diagnostic imaging , Tomography, X-Ray Computed , Chondroma/surgery , Chondroma/diagnostic imaging , Fatal Outcome , Paraganglioma, Extra-Adrenal/surgery , Paraganglioma, Extra-Adrenal/diagnostic imaging , Gastrectomy , Leiomyosarcoma/surgery , Leiomyosarcoma/diagnostic imaging , Lung Neoplasms/surgery , Lung Neoplasms/diagnostic imaging
8.
Einstein (Säo Paulo) ; 14(4): 557-560, Oct.-Dec. 2016. tab, graf
Article in English | LILACS | ID: biblio-840277

ABSTRACT

ABSTRACT Liposarcoma is one of the most common soft tissue sarcomas in adults, occurring in 15 to 20% of all patients with sarcoma. Primary liposarcoma of the stomach is rare. We report a case of patient with giant gastric liposarcoma who underwent surgery after a gastrointestinal bleeding. Preoperative hystopathological diagnosis was not established, even after three biopsy attempts. We discuss differential diagnosis, genetic causes, diagnosis strategies and treatment.


RESUMO O lipossarcoma é um tipo comum de sarcomas em adultos, com incidência entre 15 e 20% entre os sarcomas. No entanto, o acometimento do estômago é raro. Relatamos um caso de um lipossarcoma primário gástrico gigante com apresentação clínica de hemorragia digestiva. Foi submetido a tratamento cirúrgico sem diagnóstico definitivo, apesar de três biópsias realizadas. Revisamos diagnósticos diferenciais, influência genética e estratégias diagnósticas e terapêuticas.


Subject(s)
Humans , Male , Aged , Stomach Neoplasms/pathology , Liposarcoma/pathology , Stomach Neoplasms/surgery , Stomach Neoplasms/diagnostic imaging , Biopsy , Gastrointestinal Stromal Tumors , Diagnosis, Differential , Gastrointestinal Neoplasms , Liposarcoma/surgery , Liposarcoma/diagnostic imaging
11.
Clinics ; 71(4): 199-204, Apr. 2016. tab, graf
Article in English | LILACS | ID: lil-781425

ABSTRACT

OBJECTIVE: To determine whether the gross tumor volume of resectable gastric adenocarcinoma on multidetector computed tomography could predict the presence of regional lymph node metastasis and could determine N categories. MATERIALS AND METHODS: A total of 202 consecutive patients with gastric adenocarcinoma who had undergone gastrectomy 1 week after contrast-enhanced multidetector computed tomography were retrospectively identified. The gross tumor volume was evaluated on multidetector computed tomography images. Univariate and multivariate analyses were performed to determine whether the gross tumor volume could predict regional lymph node metastasis, and the Mann-Whitney U test was performed to compare the gross tumor volume among N categories. Additionally, a receiver operating characteristic analysis was performed to identify the accuracy of the gross tumor volume in differentiating N categories. RESULTS: The gross tumor volume could predict regional lymph node metastasis (p<0.0001) in the univariate analysis, and the multivariate analyses indicated that the gross tumor volume was an independent risk factor for regional lymph node metastasis (p=0.005, odds ratio=1.364). The Mann-Whitney U test showed that the gross tumor volume could distinguish N0 from the N1-N3 categories, N0-N1 from N2-N3, and N0-N2 from N3 (all p<0.0001). In the T1-T4a categories, the gross tumor volume could differentiate N0 from the N1-N3 categories (cutoff, 12.3 cm3), N0-N1 from N2-N3 (cutoff, 16.6 cm3), and N0-N2 from N3 (cutoff, 24.6 cm3). In the T4a category, the gross tumor volume could differentiate N0 from the N1-N3 categories (cutoff, 15.8 cm3), N0-N1 from N2-N3 (cutoff, 17.8 cm3), and N0-N2 from N3 (cutoff, 24 cm3). CONCLUSION: The gross tumor volume of resectable gastric adenocarcinoma on multidetector computed tomography could predict regional lymph node metastasis and N categories.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Young Adult , Stomach Neoplasms/pathology , Adenocarcinoma/secondary , Tumor Burden , Multidetector Computed Tomography/methods , Lymph Nodes/diagnostic imaging , Prognosis , Stomach Neoplasms/surgery , Stomach Neoplasms/diagnostic imaging , Adenocarcinoma/surgery , Adenocarcinoma/diagnostic imaging , Observer Variation , Multivariate Analysis , Retrospective Studies , ROC Curve , Neoplasms, Glandular and Epithelial/pathology , Lymph Nodes/pathology , Lymphatic Metastasis , Neoplasm Staging
12.
Article in English | WPRIM | ID: wpr-165884

ABSTRACT

BACKGROUND/AIMS: This study evaluated the diagnostic efficacy of fluorine-18 fluorodeoxyglucose PET/CT (F-18 FDG PET/CT) for patients with gastric mucosa-associated lymphoid tissue (MALT) lymphoma and examined the association between FDG avidity and the clinical factors affecting lesions. METHODS: Among the patients diagnosed with gastric MALT lymphoma, 16 who underwent a PET/CT for gastric MALT lymphoma were semi-quantitatively and qualitatively tested for FDG avidity of lesions in the stomach. Retrospectively collected data was analyzed to investigate the clinicoradiological factors and endoscopic findings between the patients with positive F-18 FDG PET/CT scans and those with negative scans. RESULTS: Eight of the 16 patients showed FDG avidity. When comparing the size of lesions in the stomach, the patients with FDG avidity had significantly larger lesions than those without (28.8 mm vs. 15.0 mm, p=0.03). The FDG-avid group has a significantly higher rate of positive CT scans than the non-avid group (75% vs. 13%, p=0.03). According to the endoscopic finding of the lesions, FDG avidity was pronounced with 75% of the protruding tumors, and 100% of the erosive-ulcerative types, which are a type of depressed tumors. CONCLUSIONS: When gastric MALT lymphoma is large, when lesions are found using abdominal CT scans, and the macroscopic appearance of a lesion is that of a protruding tumor or erosive-ulcerative type of depressed tumor, there is a high probability that such patients may have a positive F-18 FDG PET/CT scan.


Subject(s)
Aged , Female , Fluorodeoxyglucose F18/chemistry , Gastroscopy , Humans , Lymphoma, B-Cell, Marginal Zone/diagnosis , Male , Middle Aged , Positron Emission Tomography Computed Tomography , Retrospective Studies , Stomach Neoplasms/diagnostic imaging
13.
Gac. méd. espirit ; 15(3): 324-330, sep.-dic. 2013.
Article in Spanish | LILACS | ID: lil-696671

ABSTRACT

Fundamento: el cáncer gástrico es una de las principales causas de muerte. En Cuba la mayoría son diagnosticados en fases avanzadas ensombreciendo el pronóstico. La linitis plástica es una forma de crecimiento submucoso del adenocarcinoma. Objetivo: ofrecer lección a médicos sobre los signos endoscópicos de sospecha y complementarios a utilizar para diagnosticarlo rápidamente. Presentación de caso: paciente que refería epigastralgia, vómitos y pérdida de peso. La radiografía contrastada de estómago evidenció rigidez y defecto de lleno en curvatura mayor y menor. La esofagogastroduodenoscopía mostró ausencia de peristalsis y estenosis de la luz del estómago. En el examen laparoscópico se observó exteriorización del tumor. El diagnóstico definitivo se realizó por macrobiopsia después de la cirugía. Conclusiones: se ha de sospechar la entidad ante un paciente con la clínica sugestiva de tumor y hallazgos endoscópicos como la disminución de la peristalsis y la reducción de la luz del órgano.


Background: gastric cancer is one of the main causes of death. In Cuba most of the cases are diagnosed in advanced stages clouding the outlook. The plastic linitis is a form of submucosal growth adenocarcinoma. Objective: to provide medical lesson on endoscopic signs of suspicion and complementary use to diagnose it quickly. Case Presentation: a patient referred epigastralgia, vomiting and weight loss. The stomach contrasted radiography showed stiffness and squarely defect in major and minor curvature. The esophagogastroduodenoscopy showed absence of peristalsis and stenosis of the light of the stomach. In the laparoscopic exam the tumor externalization was observed. The final diagnosis was carried out by macrobiopsy after surgery. Conclusions: doctors have to suspect the disease in a patient with clinical suggestive features of tumor and endoscopic findings as decreased peristalsis and reduced organ light.


Subject(s)
Humans , Stomach Neoplasms/surgery , Stomach Neoplasms/diagnosis , Stomach Neoplasms/diagnostic imaging , Stomach Neoplasms/complications , Endoscopy, Digestive System/instrumentation
14.
IPMJ-Iraqi Postgraduate Medical Journal. 2010; 9 (1): 36-40
in English | IMEMR | ID: emr-98235

ABSTRACT

The tumor stage of gastric cancer in the preoperative period must be evaluated to choose the type of therapy so the preoperative imaging diagnosis is the basis for a tumor-stage -adapted therapy of each patient. Is to compare between the preoperative staging of gastric cancer which includes the ultrasound scan, CT scan and EUS findings and the postoperative staging which include the histopathological finding and to assess the efficacy of EUS in determining the tumor and lymph node stage of tumor. Prospective study of 32 patients with gastric cancer admitted to the surgical word in the gastroenterology and hepatology teaching hospital, medical city, Baghdad over the period from Nov. 2005 to Nov. 2007 who underwent gastric resection, all the cases were proved to be gastric cancer by endoscopic biopsy or by histopathological examination of the gastric specimen after operative resection, and all the cases radiologically investigated in the preoperative period by abdominal ultrasound, endoluminal ultrasound and abdominal CT scan. Show that there is increase in the staging in 18 [56.25%] cases and same staging in 8 [25%] cases and decrease staging in 6 [18.75%] cases. Endoluminal ultrasound is most accurate preoperative investigation to determine staging of gastric malignancy. Ultrasound and CT scan although it is important in the assessment but they downstage the tumor in about half of cases. So we recommend that EUS is done for all patients with gastric cancer for accurate planning for surgery


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Neoplasm Staging , Prospective Studies , Stomach Neoplasms/diagnostic imaging , Tomography, X-Ray Computed
15.
Article in English | WPRIM | ID: wpr-198280

ABSTRACT

A lymphoepithelioma-like carcinoma, characterized by a carcinoma with heavy lymphocyte infiltration, is one of the histological patterns observed in patients with Epstein-Barr virus (EBV)-associated gastric carcinoma. Less than half of invasive carcinomas with lymphoepithelioma-like histology can grow to make a submucosal mass. These tumors generally have a better prognosis than conventional adenocarcinomas. We report a case of an EBV-associated lymphoepithelioma-like gastric carcinoma that presented as a submucosal mass on multi-detector (MD) CT and correlate them with the pathology.


Subject(s)
Carcinoma/diagnostic imaging , Contrast Media , Diagnosis, Differential , Epstein-Barr Virus Infections/diagnostic imaging , Gastroscopy , Humans , In Situ Hybridization , Male , Middle Aged , Stomach Neoplasms/diagnostic imaging , Tomography, X-Ray Computed
16.
Article in English | WPRIM | ID: wpr-123970

ABSTRACT

Primary gastric carcinoma is the most common cause of linitis plastica. Less frequently, metastatic gastric cancer from the breast, omental metastases and non-Hodgkin lymphoma involving the stomach have been reported to show similar radiographic findings as for linitis plastica. A metastatic gastric cancer from bladder cancer is extremely rare. We present an unusual case, the first to our knowledge, of gastric linitis plastica that resulted from a metastatic urothelial carcinoma of the bladder.


Subject(s)
Diagnosis, Differential , Humans , Linitis Plastica/diagnostic imaging , Male , Middle Aged , Stomach Neoplasms/diagnostic imaging , Tomography, X-Ray Computed , Urinary Bladder Neoplasms/pathology
17.
Article in Korean | WPRIM | ID: wpr-19819

ABSTRACT

BACKGROUND/AIMS: The multidetector computed tomography (MDCT) scanning frequently leads to the incidental discovery of bowel wall thickening. The aim of this study was to determine the utility of gastroscopy and colonoscopy in the management of patients who had incidental discovery of bowel wall thickening on MDCT. METHODS: From May 2006 to March 2008, the abdominal MDCT reports of all patients in Chungbuk National University Hospital were reviewed. Cases with any bowel thickening was selected and then patients who received gastroscopy or colonoscopy after abdominal MDCT were re-selected. RESULTS: Gastroscopy revealed abnormal findings in 22 (95.7%) out of 23 patients, and 10 patients (43.5%) had stomach cancers. Colonoscopy revealed abnormal findings in 35 (85.4%) out of 41 patients, and 12 patients (29%) had malignant tumors. In the patients who had lymph node enlargement (p<0.001), dirty fat infiltration (p=0.025), and irregular wall thickening (p<0.001) on MDCT malignancy was observed more frequently. CONCLUSIONS: We recommend gastroscopy and colonoscopy to patients who had incidentally found bowel wall thickening on MDCT, especially those with lymph node enlargement, dirty fat infiltration, and irregular wall thickening.


Subject(s)
Adult , Aged , Aged, 80 and over , Colonic Neoplasms/diagnostic imaging , Endoscopy, Gastrointestinal , Female , Humans , Intestines/cytology , Male , Middle Aged , Retrospective Studies , Stomach Neoplasms/diagnostic imaging , Tomography, X-Ray Computed/methods
18.
Article in English | WPRIM | ID: wpr-101655

ABSTRACT

OBJECTIVE: We wanted to prospectively evaluate the effect of various positions of the patient on gastric distension and lesion conspicuity during performance of CT gastrography (CTG). MATERIALS AND METHODS: One hundred thirteen consecutive patients with gastric cancer underwent CTG in the 30degrees left posterior oblique (LPO), supine, and prone positions. Two radiologists scored (a grade from 1-4) the degree of gastric distension and the lesion conspicuity according to the three scanning positions and the three gastric portions. Two- (2D) and three-dimensional (3D) images were used for analysis. Finally, these data were compared with the endoscopic findings and surgical results. RESULTS: The mean scores of gastric distension and lesion conspicuity for the LPO and supine positions were higher than those for the prone position (p or = 0.21). As for the gastric upper portion, the mean scores of gastric distension in the prone position were higher than those in the two other positions (p < 0.001). The prone position showed better lesion conspicuity than the two other positions for only one of two cases of gastric cancer in the upper portion of the stomach. CONCLUSION: CTG performed in the LPO position or the supine position combined with CTG performed in the prone position is optimal for achieving good gastric distension and evaluating the lesion conspicuity of gastric cancer.


Subject(s)
Female , Humans , Image Processing, Computer-Assisted/methods , Imaging, Three-Dimensional/methods , Male , Middle Aged , Observer Variation , Posture , Prospective Studies , Stomach/diagnostic imaging , Stomach Neoplasms/diagnostic imaging , Tomography, X-Ray Computed/methods
19.
Rev. AMRIGS ; 48(2): 86-89, abr.-jun. 2004. tab
Article in Portuguese | LILACS | ID: biblio-876506

ABSTRACT

Foram revisados 115 prontuários de pacientes internados no Hospital Nossa Senhora da Conceição, em um período de 2 anos, com diagnóstico de câncer gástrico confirmado histolopatologicamente. A incidência foi maior entre homens (2:1), sendo identificada relação entre câncer gástrico e tabagismo, presente em 58,2% dos pacientes. Não foi possível estabelecer relação etiológica com alcoolismo e com história pessoal ou familiar de outras neoplasias. A apresentação endoscópica mais freqüente foi tumor ulcerado (44,7% dos casos), sendo adenocarcinoma o tipo histopatológico mais prevalente. No estadiamento, 67% dos pacientes que realizaram ecografia ou tomografia abdominal apresentaram alterações que sugeriram a presença do tumor ou sua disseminação e 56,5% dos pacientes apresentavam neoplasia gástrica irressecável no momento do diagnóstico. Novos ensaios clínicos randomizados são necessários para o reconhecimento dos fatores de risco para esta neoplasia e possibilitar o estabelecimento de medidas de prevenção e detecção precoce do câncer gástrico em pacientes de alto risco (AU)


The registers of 115 patients with diagnosis of gastric cancer (histopathologically confirmed) from Hospital Nossa Senhora da Conceição in a 2 year period were studied. The incidence was larger among men (2:1), and a relationship between gastric cancer and tobacco smoking, present in 58,2% of the patients, was identified. It was not possible to establish etiological relationship with alcoholism and personal or family history of another neoplasm. The more frequent endoscopic presentation was ulcerated tumor (44,7% of the cases), being adenocarcinoma the more prevalent histopathologic type. Sixty seven percent of the patients that were submitted to abdominal ecography or tomography presented alterations that suggested the presence of the tumor or its dissemination, and 56,5% of the patients presented irresecable gastric cancer in the moment of the diagnosis. New randomized clinical trials are necessary for the recognition of the risk factors for this neoplasm and then establish prevention measures and early detection of gastric cancer in high risk patients (AU)


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Adenocarcinoma/epidemiology , Gastrointestinal Stromal Tumors/epidemiology , Lymphoma/epidemiology , Stomach Neoplasms/epidemiology , Adenocarcinoma/etiology , Brazil/epidemiology , Lymphoma/etiology , Retrospective Studies , Risk Factors , Stomach Neoplasms/diagnostic imaging , Stomach Neoplasms/etiology
20.
Article in English | IMSEAR | ID: sea-39051

ABSTRACT

OBJECTIVE: To evaluate the sensitivity, specificity and accuracy of the double-contrast upper gastrointestinal series (UGI series) in the diagnosis of gastric cancer. MATERIAL AND METHOD: The authors retrospectively reviewed the radiographs of the double-contrast UGI series for diagnosis of gastric cancer of 84 patients who had pathological confirmation by gastric biopsies and/or operations. RESULTS: The lesions were true positive in 45 patients, true negative in 28 patients, false positive in 8 patients and false nagative in 3 patients. The authors found pathologically proved gastric cancers in 48 patients. They were 42 adenocarcinomas (87.5%), 3 gastric mucosa-associated lymphoid tissue lymphomas (6.2%), one gastrointestinal stromal tumor (2.1%), one squamous cell carcinoma at the distal esophagus involving the cardia (2.1%) and one cancer of the pancreatic head with invading gastric antrum (2.1%). The sensitivity, specificity and accuracy of the present study were 93 per cent, 77 per cent and 86 per cent, respectively. They showed small differences compared to the previous studies. CONCLUSION: The present findings indicate that the double-contrast UGI series has high sensitivity, specificity and accuracy. It should be considered a sensitive technique and initial examination in the diagnosis of gastric cancer.


Subject(s)
Adenocarcinoma/diagnostic imaging , Adult , Aged , Aged, 80 and over , Barium Sulfate/diagnosis , Female , Humans , Lymphoma, B-Cell, Marginal Zone/diagnostic imaging , Male , Middle Aged , Reproducibility of Results , Retrospective Studies , Sensitivity and Specificity , Stomach/diagnostic imaging , Stomach Neoplasms/diagnostic imaging
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