Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 285
Filter
1.
Arq. bras. cardiol ; 117(3): 426-434, Sept. 2021. tab
Article in English, Portuguese | LILACS | ID: biblio-1339193

ABSTRACT

Resumo Fundamento: A fibrilação ou flutter atrial (FFA) é a arritmia cardíaca sustentada mais comum. Existem poucos dados sobre a epidemiologia da FFA na América do Sul. Objetivo: O presente estudo procurou descrever a epidemiologia clínica da FFA e o uso de anticoagulantes na avaliação da linha de base do Estudo Longitudinal da Saúde do Adulto (ELSA-Brasil). Métodos: Foram analisados dados de 13.260 participantes do ELSA-Brasil. A FFA foi definida pelo eletrocardiograma ou por autorrelato. Modelos de regressão logística foram construídos para analisar fatores associados à FFA. Este estudo também analisou se idade e sexo estavam associados ao uso de anticoagulantes para evitar acidente vascular cerebral. O nível de significância foi de 5%. Resultados: A idade mediana foi de 51 anos, e 7.213 (54,4%) participantes eram mulheres. A FFA foi detectada em 333 (2,5%) participantes. O aumento da idade (razão de chances [RC]:1,05; intervalo de confiança de 95% [IC95%]: 1,04-1,07), hipertensão (RC:1,44; IC95%:1,14-1,81) coronariopatia (RC: 5,11; IC95%:3,85-6,79), insuficiência cardíaca (RC:7,37; IC95%:5,00-10,87) e febre reumática (RC:3,38; IC95%:2,28-5,02) foram associadas à FFA. Dos 185 participantes com FFA e pontuação no CHA2DS2-VASc≥2, apenas 20 (10,8%) usavam anticoagulantes (50,0% entre aqueles com FFA no eletrocardiograma de linha de base). O uso de anticoagulantes nesse grupo foi associado a maior idade (1,8% vs 17,7% naqueles com idade ≤ 54 e ≥ 65 anos, respectivamente; p=0,013). Observou-se uma tendência ao menor uso de anticoagulantes em mulheres (7,1% vs. 16,4% em mulheres e homens, respectivamente; p=0,055). Conclusões: No recrutamento do ELSA-Brasil, 2,5% dos participantes tinham FFA. O baixo uso de anticoagulantes era comum, o que representa um desafio para os cuidados de saúde nesse cenário.


Abstract Background: Atrial fibrillation or flutter (AFF) is the most common sustained cardiac arrhythmia. Limited data can be found on AFF epidemiology in South America. Objective: The present study sought to describe the clinical epidemiology of AFF and the use of stroke prevention medication in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) baseline assessment. Methods: This study analyzed data from 13,260 ELSA-Brasil participants. AFF was defined according to ECG recording or by self-report. Logistic regression models were built to analyze factors associated with AFF. This study also analyzed if age and sex were associated with anticoagulant use for stroke prevention. Significance level was set at 5%. Results: Median age was 51 years and 7,213 (54.4%) participants were women. AFF was present in 333 (2.5%) participants. Increasing age (odds ratio [OR]:1.05; 95% confidence interval [95%CI]: 1.04-1.07), hypertension (OR:1.44; 95%CI: 1.14-1.81), coronary heart disease (OR: 5.11; 95%CI: 3.85-6.79), heart failure (OR:7.37; 95%CI: 5.00-10.87), and rheumatic fever (OR:3.38; 95%CI: 2.28-5.02) were associated with AFF. From 185 participants with AFF and a CHA2DS2-VASc score ≥2, only 20 (10.8%) used anticoagulants (50.0% among those with AFF in the baseline ECG). Stroke prevention in this group was associated with a higher age (1.8% vs 17.7% in those aged ≤ 54 and ≥ 65 years, respectively; p=0.013). A trend towards a reduced anticoagulant use was observed in women (7.1% vs. 16.4% in women and men, respectively; p=0.055). Conclusions: At the ELSA-Brasil baseline, 2.5% of the participants had AFF. The lack of stroke prevention was common, which is an especially challenging point for healthcare in this setting.


Subject(s)
Humans , Male , Female , Adult , Aged , Atrial Fibrillation/diagnosis , Atrial Fibrillation/epidemiology , Stroke/diagnosis , Stroke/prevention & control , Stroke/epidemiology , Cross-Sectional Studies , Risk Factors , Longitudinal Studies , Risk Assessment , Electrocardiography , Self Report , Middle Aged , Anticoagulants/therapeutic use
2.
Horiz. enferm ; 32(1): 55-63, 2021. tab
Article in Spanish | LILACS, BDENF | ID: biblio-1224722

ABSTRACT

INTRODUCCIÓN: El Accidente cerebrovascular corresponde a una patología súbita, que requiere de atención inmediata, donde se ve comprometida una región cerebral por obstrucción de un vaso sanguíneo, en la mayoría de los casos. OBJETIVOS: Determinar el nivel de conocimiento respecto al accidente cerebrovascular que presenta la población masculina de 25 a 55 años del condominio Las Palmas de Maipú en el año 2020, Identificar si la población masculina reconoce signos, síntomas, factores de riesgos y acciones a tomar frente a un ACV. MÉTODOS: Estudio transversal, descriptivo, Se reclutaron 80 participantes masculinos residentes de condominio Las Palmas de Maipú, Chile. Instrumento y mediciones: Cuestionario tipo encuesta, considerando como variable primaria el nivel de conocimientos de la población y secundaria las variables sociodemográficas. RESULTADOS: Se evaluaron 80 participantes masculinos con rango etario de 25 a 55 años, se obtuvo como resultado un relativo conocimiento respecto a los ACV, reconociéndolo como una emergencia médica (93%), que requiere de un tratamiento oportuno (85%). No obstante, se evidencia un déficit de conocimiento sobre los factores de riesgos asociados a un ACV (30%). CONCLUSIONES: Se evidencia que la población masculina estudiada, si bien distingue la importancia clínica de un ACV, existe un déficit de conocimiento sobre los factores predisponentes para la presencia de este, lo que resulta relevante a considerar en la prevención de un evento cerebrovascular.


INTRODUCTION: Stroke corresponds to a sudden pathology, which requires immediate attention, where a brain region is compromised by obstruction of a blood vessel, in most cases. OBJECTIVES: Determine the level of knowledge regarding stroke in the male population aged 25 to 55 years of the Las Palmas de Maipú condominium in 2020, Identify if the male population recognizes signs, symptoms, risk factors and actions to be taken. to a stroke. METHODS: Cross-sectional, descriptive study. 80 male participants were recruited from the Las Palmas de Maipú condominium, Chile. Instrument and measurements: Survey-type questionnaire, considering the level of knowledge of the population as the primary variable and the sociodemographic variables as secondary. RESULTS: 80 male participants with an age range of 25 to 55 years were evaluated, a relative knowledge regarding stroke was obtained as a result, recognizing it as a medical emergency (93%), which requires timely treatment (85%). However, there is evidence of a deficit in knowledge about the risk factors associated with stroke (30%). CONCLUSIONS: It is evident that the male population studied, although it distinguishes the clinical importance of a stroke, there is a deficit of knowledge about the predisposing factors for its presence, which is relevant to consider in the prevention of a cerebrovascular event.


Subject(s)
Humans , Male , Adult , Middle Aged , Health Knowledge, Attitudes, Practice , Stroke/diagnosis , Chile , Cross-Sectional Studies , Risk Factors , Educational Status , Men's Health
3.
ABC., imagem cardiovasc ; 34(3)2021. ilus
Article in Portuguese | LILACS | ID: biblio-1292756

ABSTRACT

O sinal RAC (retroaortic anomalous coronary ou artéria coronária anômala retroaórtica) é um achado desconhecido, descrito ao ecocardiograma transtorácico como uma estrutura tubular ecogênica, localizada na face atrial do sulco atrioventricular. Apresentamos um caso onde o sinal RAC se apresenta na ecocardiografia transesofágica (ETE). O conhecimento do sinal RAC e a avaliação com ETE aumentam a sensibilidade e a especificidade e conferem a oportunidade de avaliar características anatômicas de alto risco, importantes na avaliação do risco de morte súbita.(AU)


Subject(s)
Humans , Middle Aged , Myocardial Ischemia/etiology , Coronary Vessel Anomalies/genetics , Stroke/diagnosis , Death, Sudden/etiology , Heart Defects, Congenital , Sinus of Valsalva/abnormalities , Echocardiography/methods , Echocardiography, Transesophageal/methods
4.
Rev. Méd. Clín. Condes ; 31(5/6): 487-490, sept.-dic. 2020. ilus
Article in Spanish | LILACS | ID: biblio-1224145

ABSTRACT

OBJETIVO Informar Sobre Un Caso De Infarto Simultáneo Cardio-Cerebral Y Sus Características, Comparado Con Lo Descrito En La Actualidad. CASO CLÍNICO Paciente Femenina De 64 Años, Con Infarto Simultáneo Cardio-Cerebral (Isquemia En Territorio De Arteria Cerebral Media Derecha Y Elevación Del Segmento St En Cara Antero Inferior), Tratada Con Fibrinólisis. RESULTADOS Evoluciona Con Sensorio Fluctuante, Requiriendo Intubación Orotraqueal Y Manejo En Unidad De Terapia Intensiva Por Sangrado Cerebral CONCLUSIONES El infarto simultáneo cardio-cerebral es infrecuente y representa un desafío para el equipo de salud a fin de evitar que el manejo temprano de una condición retrase la otra


OBJETIVE To Report On A Case Of Simultaneous Cardio-Cerebral Infarction And Its Characteristics, Compared With What Is Currently Described. CLINICAL CASE A 64-year-old female patient with simultaneous cardio-cerebral infarction (ischemia in the territory of the right middle cerebral artery and elevation of the st segment in the lower anterior aspect), treated with fibrinolysis. RESULTS It evolves with fluctuating sensory, requiring orotracheal intubation and management in intensive therapy unit due to cerebral bleeding. CONCLUSIONS The Simultaneous Cardio-Cerebral Infarction Is Infrequent And Represents A Challenge For The Health Team In Order To Avoid That The Early Management Of One Condition Delays The Other


Subject(s)
Humans , Female , Middle Aged , Stroke/complications , Myocardial Infarction/complications , Stroke/diagnosis , Stroke/therapy , Electrocardiography , Myocardial Infarction/diagnosis , Myocardial Infarction/therapy
5.
Med. infant ; 27(2): 92-100, Diciembre 2020. Tab, ilus
Article in Spanish | LILACS, BINACIS, UNISALUD | ID: biblio-1147907

ABSTRACT

Introducción: La incidencia de ACV (Accidente Cerebrovascular) en niños es de 2-13/100.000 niños por año, siendo una de las 10 causas más frecuentes de muerte en la infancia. La misma varía entre 6-40% dependiendo de las series publicadas y de los subtipos de ACV. Existen diferencias importantes entre el ACV en niños y adultos, ya que las características neurológicas y de la hemostasia son muy distintas en cada grupo. En niños deben ser investigados múltiples factores de riesgo que a menudo se superponen entre sí. Materiales y métodos: Trabajo descriptivo retrospectivo por revisión de historias clínicas, de una población de niños con diagnóstico de ACV ingresados en UCIP en un período de 10 años. Resultados: Se confirmó el diagnóstico de ACV en un total de 84 pacientes. El 70,24% de la población correspondía a ACVH (Accidente Cerebrovascular Hemorrágico) y un 29,76% ACVI (Accidente Cerebrovascular Isquémico). El 60,71 % eran masculinos. La mediana del tiempo entre el inicio de los síntomas y el ingreso a UCIP, en ambos grupos fue de 1 día con rango entre 1-17 días para los ACVH y 1-9 para los ACVI. Se evaluaron variables clínicas, de diagnóstico y de tratamiento según ambos tipos de ACV. Conclusión: El ACV requiere de un abordaje multidisciplinario. La realización de neuro-imágenes es un pilar fundamental para el diagnóstico y no debe ser pospuesto. El monitoreo y tratamiento está enfocado en minimizar el daño en el parénquima cerebral circundante (AU)


Introduction: The incidence of stroke in children is 2-13/100,000 children a year, being one of the 10 most common causes of death in childhood. Mortality varies between 6 and 40% depending on the series reported and according to the different subtypes of stroke. There are important differences between childhood and adult stroke, as the neurological features and characteristics of hemostasis vary greatly. In children, multiple risk factors that often overlap should be investigated. Material and methods: A retrospective descriptive review of the clinical records of a series of patients with stroke admitted to the pediatric intensive care unit (PICU) over a period of 10 years was conducted. Results: The diagnosis of stroke was confirmed in 84 patients; 70.24% had hemorrhagic and 29.76% ischemic stroke. Overall, 60.71% were boys. Median time between symptom onset and admission to the PICU was one day in both groups, ranging from 1-17 días for those with hemorrhagic and from 1-9 days for those with ischemic stroke. Clinical, diagnostic, and treatment variables were evaluated for both types of stroke. Conclusion: Stroke requires a multidisciplinary approach. Neuroimaging is essential for the diagnosis and should not be postponed. Monitoring and treatment is focused on minimizing damage to the surrounding brain parenchyma (AU)


Subject(s)
Humans , Infant , Child, Preschool , Child , Adolescent , Intensive Care Units, Pediatric , Cerebral Hemorrhage , Brain Ischemia , Stroke/surgery , Stroke/classification , Stroke/diagnosis , Stroke/etiology , Stroke/epidemiology , Stroke/diagnostic imaging , Retrospective Studies
6.
Rev. bras. neurol ; 56(3): 11-14, jul.-set. 2020. tab
Article in Portuguese | LILACS | ID: biblio-1120376

ABSTRACT

INTRODUÇÃO: O Acidente Vascular Cerebral (AVC) é uma das principais causas de morbi-mortalidade na América Latina, poucos estudos avaliam o conhecimento da população brasileira sobre o mesmo. OBJETIVO: Avaliar o conhecimento da população de Torres/RS sobre fatores de risco e sinais/sintomas de AVC. MÉTODO: Foi realizado um estudo do tipo transversal de caráter descritivo e exploratório, com entrevista a 375 habitantes, no qual responderam a dois questionários, um sociodemográfico e outro relativo ao conhecimento dos sinais e sintomas do Acidente vascular cerebral. O teste de Qui-Quadrado (χ2) e teste T-student foram realizados para avaliar a associação existente entre as variáveis qualitativas e para verificar diferenças na frequência absoluta e percentual das variáveis. RESULTADOS: A idade média dos participantes foi de 39,7 (+/- 14,6) anos, sendo 230 mulheres, a média de acertos sobre fatores de risco foi de 3.7/11 (34.4%) e de reconhecimento de sinais/sintomas foi de 3,2/10 (32,5%). Em relação aos fatores de risco, Hipertensão Arterial Sistêmica foi descrita por 229 (17,4%) indivíduos e quanto aos sinais/sintomas, o mais descrito foi a Paralisia Facial Central, relatada por 197 (17,2%). Além disso, foi observado que indivíduos com menor nível de instrução, do sexo masculino e com menos de 39 anos, apresentaram um pior desempenho em relação ao conhecimento sobre AVC. CONCLUSÃO: Dessa forma, sugere-se a necessidade de implementar políticas públicas que levem à população informações sobre a importância do reconhecimento destes sinais e sintomas com a necessidade do socorro rápido a este paciente.


INTRODUCTION: Stroke is a leading cause of mortality and disability in Latin America and few paper evaluate the knowledge of brazilian population about this subject. OBJECTIVE: Evaluate the knowledge of Torres/RS about stroke risk factors and signs/symptoms of stroke. METHODS: It was performed a transversal study with 375 inhabitants of Torres, in which they answered two questionnaires, a sociodemographic and the other related to the knowledge of the signs and symptoms of stroke. The Chi-square test (χ2) and the T-student test were performed to assess the association between qualitative variables and to verify differences in the absolute frequency and percentage of variables. RESULTS: The mean age of the participants was 39.7 (+/-14.6) years, (230 were women). The average of correct answers about risk factors was 3.7/11 (34.4%) and recognition of signs/symptoms was 3.2/10 (32.5%). Systemic Arterial Hypertension was the risk factor most recognized by the population (229 individuals). Facial Paralysis reported by 197 individuals was the signs/symptoms most recognized by the Torres population. In addition, it was observed that individuals with a lower level of education, male and under 39 years old, presented a worse performance in relation to knowledge about stroke. CONCLUSION: The implementation of public policies that provide the population information about the importance of the early recognization of stroke signs and symptoms is fundamental for a better result in the care of this disease.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Young Adult , Health Knowledge, Attitudes, Practice , Stroke/diagnosis , Cross-Sectional Studies , Surveys and Questionnaires , Risk Factors
7.
Rev. cuba. med. mil ; 49(1): e494, ene.-mar. 2020. tab, fig
Article in English, Spanish | LILACS, CUMED | ID: biblio-1126686

ABSTRACT

Introduction: The present investigation arises from the insufficiencies in the physical rehabilitation of the hemiparesic patients of the orthopedic center of Viana, in many cases, determined by the low preparation of the physiotherapists for the use of the physical exercises with therapeutic aims. Objective: To elaborate a set of therapeutic physical exercises to favor the physical rehabilitation of patients diagnosed with hemiparesis. Methods: To develop the present investigation, the following methods were used: analytical-synthetic, hypothetical-deductive, inductive-deductive and systemic-structural-functional; and as empirical methods were used document analysis, observation, the Tinetti test and the experiment, which were supported by the survey and interview techniques, as well as by the statistical-mathematical empirical frequency distribution method. Conclusions: The correct selection, dosage and application of the physical therapeutic exercises allowed favoring the physical rehabilitation of two patients diagnosed with hemiparesis of the orthopedic center of Viana, results evaluated by the Tinetti test(AU)


Introducción: La presente investigación surge de las insuficiencias en la rehabilitación física de los pacientes hemiparésicos del centro ortopédico de Viana, en muchos casos, determinadas por la baja preparación de los fisioterapeutas para el uso de los ejercicios físicos con fines terapéuticos. Objetivo: Elaborar un conjunto de ejercicios físicos terapéuticos para favorecer la rehabilitación física de los pacientes diagnosticados con hemiparesia. Métodos: Para desarrollar la presente investigación se utilizaron como métodos teóricos los siguientes: analítico-sintético, hipotético-deductivo, inductivo-deductivo y sistémico-estructural-funcional; y como métodos empíricos se utilizaron el análisis de documentos, la observación, la medición, el test de Tinetti y el experimento, que fueron apoyados por las técnicas de encuesta y entrevista, así como por el método estadístico-matemático distribución empírica de frecuencias. La muestra utilizada estuvo constituida por seis pacientes y tres fisioterapeutas del centro ortopédico de Viana, Luanda, Angola. Resultados: Después del diagnóstico inicial, se elaboró el conjunto de ejercicios físicos terapéuticos, el cual se aplicó desde el mes de mayo hasta el mes de noviembre del 2018, donde se aplicó al medición final, que permitió determinar las mejoras en la rehabilitación física de los pacientes diagnosticados con hemiparesia, al mejorar la marcha y el equilibrio Conclusiones: La correcta selección, dosificación y aplicación de los ejercicios físicos terapéuticos permitió favorecer la rehabilitación física dos pacientes diagnosticados con hemiparesia del centro ortopédico de Viana, resultados evaluados mediante el test de Tinetti(AU)


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Orthopedics , Rehabilitation , Exercise , Dosage , Physical Therapists , Stroke/diagnosis
8.
Arq. neuropsiquiatr ; 78(2): 88-95, Feb. 2020. tab, graf
Article in English | LILACS | ID: biblio-1088994

ABSTRACT

Abstract A larger therapeutic window for stroke treatment requires a significant change in the organization of emergency services, avoiding the increase in number of imaging exams and indirectly the time to treatment. Objective: To highlight the relation between faster clinical evaluation and stroke over-suspicion and consequently excessive imaging acquisition. To identify predictors of ischemic stroke and stroke mimics (SM), aiming for better patient selection for comprehensive neuroimaging and reperfusion therapies. Methods: Retrospective, cohort, observational, single-center study that reviewed all consecutive files of patients presenting with acute neurological symptoms who underwent CT scan or MRI from July 1, 2016 to July 1, 2017. Results: 736 patient files were reviewed. 385 patients (52.3%) presented with confirmed acute ischemic infarct, 93 (12.6%) had another brain lesion mimicking acute ischemia, and 258 (35.1%) had normal imaging. Acute stroke was more frequent in elderly patients with atrial fibrillation, arterial hypertension, or dysarthria or right motor impairment. Stroke mimic was associated with female patients with low vascular risk factors, low NIHSS, and patients with decreased level of consciousness or symptoms suggestive of posterior circulation. Discussion: 47.7% of all patients seen at the stroke unit did not have acute stroke lesions. Clinical assessment data have been used to provide indicators of acute stroke and stroke mimic patients, and symptoms corresponding to acute stroke and stroke mimic seem to be similar in the literature. Conclusion: Considering that the number of patients admitted for stroke treatment will increase even further with a larger therapeutic window for mechanical thrombectomy and for thrombolysis, a diagnostic decision-making algorithm for stroke patients is required in order to reinforce the suspicion of stroke indicating an urgent MRI.


Resumo Uma janela terapêutica maior para o tratamento do AVC exige uma mudança significativa na organização dos serviços de emergência, para evitar o aumento do número de exames de imagem e indiretamente o tempo de tratamento. Objetivo: destacar a relação entre avaliação clínica mais rápida e suspeita de acidente vascular cerebral e, consequentemente, aquisição de imagem excessiva, e identificar preditores de acidente vascular cerebral isquêmico e imitações de acidente vascular cerebral (SM), visando uma melhor seleção de pacientes para terapias abrangentes de neuroimagem e reperfusão. Métodos: estudo observacional de coorte retrospectivo, em centro único, que revisou todos os arquivos consecutivos de pacientes com sintomas neurológicos agudos submetidos à tomografia computadorizada ou ressonância magnética de 1 de julho de 2016 a 1 de julho de 2017. Resultados: Foram revisados 736 prontuários. 385 pacientes (52,3%) apresentaram infarto isquêmico agudo confirmado, 93 (12,6%) apresentaram outra lesão cerebral imitando isquemia aguda e 258 (35,1%) apresentaram imagem normal. O AVC agudo foi mais frequente em pacientes idosos com fibrilação atrial, hipertensão arterial, ou disartria ou comprometimento motor direito. A imitação de acidente vascular cerebral foi associada a pacientes do sexo feminino com baixos fatores de risco vascular, NIHSS baixo e pacientes com diminuição do nível de consciência ou sintomas sugestivos de circulação posterior. Discussão: 47,7% de todos os pacientes atendidos na unidade de AVC não apresentaram lesões agudas de AVC. Conclusão: Considerando que o número de pacientes admitidos para tratamento de AVC aumentará ainda mais com uma janela terapêutica maior para trombectomia e trombólise IV, é necessário um algoritmo de tomada de decisão diagnóstica para pacientes com AVC, a fim de reforçar a suspeita de AVC indicando uma imagem cerebral urgente.


Subject(s)
Humans , Female , Aged , Brain Ischemia , Stroke/diagnosis , Diagnosis, Differential , Tomography, X-Ray Computed , Randomized Controlled Trials as Topic , Retrospective Studies , Treatment Outcome
9.
Braz. j. med. biol. res ; 53(12): e9174, 2020. tab, graf
Article in English | ColecionaSUS, LILACS, ColecionaSUS | ID: biblio-1132510

ABSTRACT

We aimed to investigate the association of long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 (lnc-MALAT1) with acute ischemic stroke (AIS), and its association with disease severity, inflammation, and recurrence-free survival (RFS) in AIS patients. One hundred and twenty AIS patients and 120 controls were recruited. Venous blood samples from AIS patients (within 24 h after symptoms onset) and controls (at entry to study) were collected to detect plasma lnc-MALAT1 expression by real-time quantitative polymerase chain reaction. AIS severity was assessed by the National Institutes of Health Stroke Scale (NIHSS) score. Plasma concentrations of inflammation factors (including C-reactive protein (CRP), tumor necrosis factor α (TNF-α), interleukin (IL)-6, IL-8, IL-10, IL-17, and IL-22) were measured and RFS was calculated. lnc-MALAT1 expression was decreased in AIS patients compared to controls, and it had a close correlation with AIS (AUC=0.791, 95% CI: 0.735-0.846). For disease condition, lnc-MALAT1 expression negatively correlated with NIHSS score and pro-inflammatory factor expression (including CRP, TNF-α, IL-6, IL-8, and IL-22), while it positively correlated with anti-inflammatory factor IL-10 expression. Furthermore, lnc-MALAT1 expression was elevated in AIS patients with diabetes. For prognosis, no statistical correlation of lnc-MALAT1 expression with RFS was found, while a trend for longer RFS was observed in patients with lnc-MALAT1 high expression compared to those with lnc-MALAT1 low expression.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Brain Ischemia/diagnosis , Stroke/diagnosis , RNA, Long Noncoding/genetics , Ischemic Stroke , Inflammation
10.
Pan Afr. med. j ; 35(50)2020.
Article in French | AIM, AIM | ID: biblio-1268670

ABSTRACT

Introduction : l'accident vasculaire cérébral (AVC) constitue un problème majeur de santé publique, tant par le nombre de personnes atteintes, que par ses conséquences médicales, sociales et économiques. L'objectif était de dégager les facteurs de mauvais pronostic vital à la phase aiguë de l'AVC artériel. Méthodes: il s'agit d'une étude prospective durant 4 mois portant sur les patients présentant une symptomatologie évocatrice d'AVC aux deux CHU de Sfax, Tunisie. Le suivi a été de 1 mois. Résultats: nous avons colligé 200 patients. Après un mois de suivi, la mortalité était de 19,9%. Les facteurs de mauvais pronostic vital étaient: le sexe masculin, la consommation de tabac, l'antécédent d'AVC, le score de Glasgow bas, le NIHSS élevé, les céphalées, les crises épileptiques symptomatiques aigues, le signe de Babinski, la mydriase, l'aphasie, la déviation conjuguée de la tête et des yeux, les chiffres élevés de pression artérielle systolique (PAS), pression artérielle diastolique (PAD) et pression artérielle pulmonaire (PAP), l'hyperthermie, l'hyperglycémie, l'hyperleucocytose, l'augmentation des CRP, créatinine, urée et la troponine Tc, la nature hémorragique de l'AVC, l'œdème péri lésionnel, l'effet de masse, l'engagement, la topographie sylvienne totale de l'ischémie, la présence de signes précoces d'ischémie, l'hémorragie méningée, l'inondation ventriculaire, l'hydrocéphalie, le recours à une assistance respiratoire, au traitement anti-œdémateux et antihypertenseur, la transformation hémorragique, l'épilepsie vasculaire, les complications infectieuses, métaboliques et de décubitus. Conclusion: l'identification des facteurs prédictifs du devenir vital permet d'optimiser les procédures thérapeutiques et mieux organiser les filières de prise en charge. Une étude comparative sera envisagée afin de mesurer l'impact des mesures correctives


Subject(s)
Prognosis , Stroke/diagnosis , Stroke/epidemiology , Tunisia
11.
Rev. Fac. Cienc. Méd. Univ. Cuenca ; 37(3): 37-44, dic. 2019. tab, ilus
Article in Spanish | LILACS | ID: biblio-1100097

ABSTRACT

El ictus es una de las patologías neurológicas de mayor prevalencia en el país.Objetivo: determinar la eficacia de la intervención educativa en el cambio de conocimientos, actitudes y prácticas frente a los factores de riesgo del ictus.Método: estudio experimental con muestra al azar de intervención en 68 sujetos, quienes recibieron programa educativo y al mismo tiempo actua-ron como control. Se aplicó un cuestionario sobre conocimientos, actitudes y prácticas validado pre y post intervención. Además, se realizó toma de su presión arterial, determinación del índice de masa corporal, perfil lipídico, hemoglobina glicosilada. La efectividad de la intervención educativa se representa como cambio en porcentaje pre y post intervención en un lapso de tres meses.Resultados: la media de edad fue de 61.07 años, 64.7% fueron mujeres, el porcentaje de conocimientos, actitudes y prácticas adecuadas mejoró de 61.36% a 73.7%; de 64.94% a 83.94%; 87.92% y 76.52% respectivamente. La efectividad total fue un incremento del 22%. Las variables cuantitativas como índice de masa corporal, tensión arterial, niveles de perfil lipídico, así como hemoglobina glicosilada no alcanzaron diferencia significativa.Conclusiones: existe una relación directa y eficacia mayor del 20% cuan-do los pacientes son intervenidos educativamente para modificar positiva-mente los conocimientos, actitudes y prácticas sobre los factores de riesgo de ictus.(AU).


Objective: to determine the effectiveness of the educational intervention in the change of knowledge, attitudes and practices regarding ictus.Method: It is a quasi-experimental study with a random sample of intervention in 68 subjects, who received an educational program and at the same time acted as control. A questionnaire on knowledge, attitudes and practices validated before and after intervention was applied.In addition, blood pressure, determination of body mass index, lipid profile and glycosylated hemoglobin were taken. The effectiveness of the educational intervention is represented as a change in pre and post intervention percentage in a period of three months.Results: the average age was 61.07 years, 64.7% were women, the percentage of knowledge, attitudes and appropriate practices improved from 61.36% to 73.7%; from 64.94% to 83.94%; 87.92% and 76.52% respectively. The total effectiveness was an increase of 22%. The quantitative variables such as body mass index, blood pressure, lipid profile levels, as well as glycosylated hemoglobin did not reach a significant difference.Conclusions: there is a direct and efficacy relationship greater than 20% when patients are educated to positively modify knowledge, attitudes and practices on risk factors regarding ictus. (AU).


Subject(s)
Humans , Female , Middle Aged , Aged , Health Knowledge, Attitudes, Practice/ethnology , Stroke/diagnosis , Health Education/classification
12.
Rev. bras. neurol ; 55(3): 22-28, jul.-set. 2019. tab
Article in Portuguese | LILACS | ID: biblio-1022904

ABSTRACT

FUNDAMENTO: A estesiometria é um teste quantitativo para avaliar o desempenho tátil sensorial, verificar o grau de sensibilidade cutânea por meio dos monofilamentos de nylon ao toque leve e à pressão. OBJETIVO: Verificar a utilização dos monofilamentos como instrumento de avaliação da sensibilidade de pacientes com sequela de AVE na literatura. MÉTODO: Estudo de revisão sistemática, realizado com artigos indexados na base de dados PubMed, Lilacs e Scielo, sem limitação por data de publicação, sendo a busca realizada no mês de outubro de 2018. RESULTADOS: Foram elencados dezessete estudos, após análise destes, nove foram excluídos por não preencherem os critérios de inclusão, e oito foram lidos na íntegra. Após leitura dos artigos, foram obtidos os dados referentes a: número da amostra, instrumentos de avaliação, se houve ou não intervenção, e a conclusão do estudo. CONCLUSÃO: Por mais promissor que seja o uso dos monofilamentos para avaliação sensorial, esta revisão mostrou que existem poucos estudos avaliando os pacientes com sequela de AVE com este método de avaliação, principalmente estudos clínicos.


BACKGROUND:The esthesiometry is a quantitative test to evaluate the tactile sensory performance, to verify the degree of cutaneous sensitivity through nylon monofilaments to light touch and pressure. OBJECTIVE: To verify the use of monofilaments as a tool to assess the sensitivity of patients with a sequel to stroke in the literature. METHOD: A systematic review study was carried out with articles indexed in the PubMed, Lilacs and Scielo database, without limitation by date of publication. The search was carried out in October 2018. RESULTS: Seventeen studies were analyzed, after analyzing nine were excluded because they did not meet the inclusion criteria, and eight were read in full. After reading the articles, data were obtained regarding: sample number, evaluation instruments, whether or not there was intervention, and the conclusion of the study. CONCLUSION: As promising as it may be the use of monofilaments for sensory evaluation, this review showed that there are few studies evaluating patients with sequelae of stroke with this method of evaluation, mainly clinical studies.


Subject(s)
Humans , Stroke/complications , Stroke/diagnosis , Neurologic Examination/methods , Sensory Thresholds , Sensitivity and Specificity , Somatosensory Disorders/etiology , Somatosensory Disorders/physiopathology
13.
Gac. méd. boliv ; 42(1): 59-64, jun. 2019. ilus., tab.
Article in Spanish | LILACS, LIBOCS | ID: biblio-1007039

ABSTRACT

OBJETIVOS: describir la experiencia en la implementación del protocolo de trombolisis i.v. en 18 pacientes con Accidente Cerebrovascular (ACV) isquémico en la Unidad de ACV de la Clínica Foianini, concretamente, entre septiembre de 2013 y julio de 2017. MÉTODOS: el estudio tiene un enfoque cuantitativo, tipo descriptivo y retrospectivo. Se revisó las historias clínicas de los pacientes con diagnóstico de ACV isquémico agudo, que fueron tratados con trombolitico intravenoso (Alteplasa) en el servicio UTAC, entre septiembre de 2013 y julio 2017 en Santa Cruz, Bolivia. RESULTADOS: el Tiempo Síntoma-Puerta alcanzo a 62,7 +/- 38 min, mientras que el Tiempo Puerta-Aguja fue de 53,6 +/- 15 min. y Tiempo Síntoma-Aguja 114,6 +/- 43 min. Se registraron complicaciones en 6 (33,3%). promedio de 4,6 +/- 3 días de internación en la clínica, pasando un promedio de 2,8 +/- 2 días en la Unidad de ACV. La tasa de mortalidad fue de 16,6%. Según la Escala Modficada de Rankin, tuvieron un puntaje de 0-1 mRS. CONCLUSIONES: el tiempo Puerta-Aguja en nuestro establecimiento fue de un promedio de 57 minutos, cumpliendo de esta forma la recomendación de la American Heart Association Guidelines 2013, la cual recalca que éste debe ser <60 min13.


OBJECTIVE: describe the experience in the implementation of the thrombolysis intravenous protocol in eighteen patients with acute ischemic stroke in the Stroke unit from the Foianini Clinic specifically, between September of 2013 and July of 2017. METHODS: the study has a quantitative, descriptive and retrospective approach. The medical record of the patients with the acute ischemic stroke diagnosis treated with intravenous thrombolytic (Alteplasa) in the UTAC service between September of 2013 and July 2017 in Santa Cruz Bolivia was revised. RESULTS: symptoms-Door time reached to 62.7 +/- 38 minutes. While the time Door- needle time was 53.6 +/- 15 minutes and the time symptoms- needle 114.6 +/- 3 days of internment in the clinic, passing out an average of 2.8 +/- 2 days in the stroke unit. The mortality tax was 16.6%. According to the modified Rankin Scale, it had a 0-1 mRS score. CONCLUSIONS: the time Door-needle in our establishment was an average of 57 minutes, fulfilling in this way the recommendation of the American Heart Association Guidelines 2013, which emphasize that it has to be < 60 minutes.


Subject(s)
Humans , Thrombolytic Therapy , Tissue Plasminogen Activator/administration & dosage , Stroke/diagnosis , Hypertension
14.
Medicina (B.Aires) ; 79(supl.2): 1-46, mayo 2019. ilus, graf, map
Article in Spanish | LILACS | ID: biblio-1012666

ABSTRACT

El accidente cerebrovascular es la tercera causa de muerte y la primera de discapacidad en la Argentina. Los eventos isquémicos constituyen el 80% de los casos. Los accidentes vasculares cerebrales requieren la implementación de protocolos sistematizados que permitan reducir los tiempos en la atención, la morbilidad y mortalidad. En el consenso participaron especialistas de nueve sociedades médicas relacionadas con la atención de pacientes con enfermedad cerebrovascular. Se consensuó un temario separado en capítulos y para la redacción de los mismos se conformaron grupos de trabajo con miembros de diferentes especialidades médicas. Se discutió y acordó para cada tema el nivel de recomendación en base a la mejor evidencia clínica disponible para cada tópico. Se realizó una adaptación al ámbito local de las recomendaciones cuando se consideró necesario. El sistema de la American Heart Association se utilizó para redactar las recomendaciones y su grado de evidencia. La corrección y edición fue realizada por cinco revisores externos, que no participaron en la redacción y con amplia experiencia en enfermedad vascular. Finalizado el documento preliminar, se organizó una reunión general con todos los integrantes de los grupos de trabajo y los revisores para redactar las recomendaciones definitivas. El consenso abarca la atención del paciente con accidente cerebrovascular isquémico en la fase pre-hospitalaria, evaluación inicial en la central de emergencias, terapias de recanalización (trombolisis y/o trombectomía mecánica), craniectomía descompresiva, neuroimágenes y cuidados clínicos en la internación.


Stroke is the third cause of death and the first cause of disability in Argentina. Ischemic events constitute 80% of cases. It requires the implementation of systematized protocols that allow reducing the time of care, morbidity and mortality. Specialists from nine medical societies related to the care of patients with cerebrovascular disease participated in the consensus. A separate agenda was agreed upon in chapters and for the writing of them, work groups were formed with members of different medical specialties. The level of recommendation was discussed and agreed upon for each topic based on the best clinical evidence available for each of them. An adaptation to the local scope of the recommendations was made when it was considered necessary.The American Heart Association system was used to draft the recommendations and their level of evidence. The correction and editing were done by five external reviewers, who did not participate in the writing and with extensive experience in vascular pathology. Once the preliminary document was finalized, a general meeting was held with all the members of the working groups and the reviewers to reach final recommendations. The consensus covers the management of ischemic stroke in the pre-hospital phase, initial evaluation in the emergency center, recanalization therapies (thrombolysis and/ or mechanical thrombectomy), decompressive craniectomy, neuroimaging and clinical care in the hospital.


Subject(s)
Humans , Brain Ischemia/diagnosis , Brain Ischemia/therapy , Brain Ischemia/epidemiology , Stroke/diagnosis , Stroke/therapy , Stroke/epidemiology , Argentina
16.
Medicina (B.Aires) ; 79(2): 90-94, abr. 2019. tab
Article in English | LILACS | ID: biblio-1002613

ABSTRACT

Misdiagnosis is a challenging risk in young patients with ischemic stroke that leads to delayed recognition, prevents thrombolytic therapy and increases morbidity and mortality. To assess the frequency and reasons for misdiagnosis of ischemic stroke in young adults in the emergency department, we retrospectively evaluated 101 consecutive patients. The diagnosis required both the presence of an ischemic lesion in diffusion-weighted MRI as well as neurological symptoms. Twenty-three individuals were misdiagnosed (15 females, mean age 43 years [range 26-55 years]). The most common diagnostic errors included headache/ neck pain n = 11 (48%) and peripheral vertigo n = 4 (17.3%), and the most common missed etiology was arterial dissection (AD) n = 15 (65.2%). The initial diagnosis was made by emergency physicians in 22 persons. The group with misdiagnosis had a significantly higher frequency of AD at 15 vs. 8 (p < 0.01), posterior territory involvement at 12 vs. 6 (p < 0.01), and female predominance. Misdiagnosis occurred in a third of young patients with an ischemic stroke and was more frequent in those with arterial dissection involving the posterior circulation and presenting with non-specific symptoms.


El error diagnóstico es una situación riesgosa en pacientes jóvenes con infarto cerebral, ya que conduce a demora en el reconocimiento, previene la administración de terapia trombolítica e incrementa la morbimortalidad. Para valorar la frecuencia y las razones de errores en esta población, evaluamos retrospectivamente 101 pacientes consecutivos. El diagnóstico de infarto cerebral requirió tanto la presencia de lesión isquémica aguda en resonancia magnética como también la presencia de síntomas neurológicos. Veintitrés pacientes fueron mal diagnosticados (15 mujeres, edad media 43 años, [rango 26-55 años]). El error más frecuente incluyó cefalea/cervicalgia n = 11 (48%) y vértigo periférico n = 4 (17.3%). La etiología menos sospechada fue disección arterial n = 15 (62.2%). La evaluación inicial en 22 pacientes fue realizada por emergentólogos. El grupo con errores tuvo significativamente mayor frecuencia de disección arterial 15 vs. 8 (p < 0.01), afectación del territorio posterior 12 vs. 6 (p < 0.01) y sexo femenino. En conclusión, los errores diagnósticos ocurrieron en un tercio de los pacientes jóvenes con infarto cerebral, y fueron más frecuentes en aquellos con disección arterial, compromiso del territorio posterior y síntomas de presentación inespecífica.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Brain Ischemia/diagnosis , Stroke/diagnosis , Diagnostic Errors/statistics & numerical data , Argentina/epidemiology , Severity of Illness Index , Brain Ischemia/epidemiology , Retrospective Studies , Risk Factors , Age Factors , Statistics, Nonparametric , Risk Assessment , Stroke/epidemiology
17.
Rev. bras. neurol ; 55(1): 18-24, jan.-mar. 2019. tab, ilus
Article in Portuguese | LILACS | ID: biblio-994507

ABSTRACT

INTRODUÇÃO: O acidente vascular encefálico (AVC), um importante problema de saúde pública, pode ter consequências catastróficas para o indivíduo e seus familiares. Cuidados paliativos (CP) são promovidos por equipe multiprofissional, com intuito de prevenir e aliviar sofrimentos de pacientes com doença ameaçadora à vida e de seus familiares. OBJETIVOS: Identificar necessidades de CP em pacientes com AVC agudo grave e seus familiares. MÉTODOS: Uma revisão sistemática foi conduzida nas bases de dados: MEDLINE, PubMed, SciELO, LILACS, DOAJ e Cochrane, em artigos publicados no período de 2000 a 2018. RESULTADOS: Dos 114 artigos encontrados na busca inicial, 16 foram selecionados após aplicação de critérios de inclusão e exclusão. Mostraram discussões sobre prognóstico; prevalência de sintomas e principais barreiras de comunicação. Foi evidenciado que estes pacientes e seus familiares têm necessidades multidimensionais não atendidas. O principal motivo para solicitar CP foi a abordagem de diretivas avançadas de vontade e de cuidados de fim-de-vida. CONCLUSÃO: Há indicação e beneficio à inserção de cuidados paliativos em pacientes acometidos por AVC agudo grave. Para isto, são fundamentais: o trabalho interdisciplinar da equipe de saúde, boa comunicação, estratégias educacionais e deliberação política.


BACKGROUND: Stroke, an important public health problem, can have catastrophic consequences for the individual and his or her family. Palliative care (PC) is promoted by a multiprofessional team to prevent and alleviate the suffering of patients with life-threatening illness and their relatives. OBJECTIVES: To identify needs to PC in severe acute stroke patients and their relatives. METHODS: A systematic review was conducted in the databases MEDLINE, PubMed, SciELO, LILACS, DOAJ and Cochrane in articles published from 2000 to 2018. RESULTS: Of the 114 articles found in the initial search, 16 were selected after application of inclusion and exclusion criteria. They showed discussions about prognosis; prevalence of symptoms and main communication barriers. It was evidenced that these patients and their families have multidimensional needs not met. The main reason for requesting PC was an approach to end-of-life decision-making and end-of-life care. CONCLUSION: There is indication and benefit the insertion of palliative care in patients affected by severe acute stroke. For this, the interdisciplinary work of the health team, good communication, educational strategies and political deliberation are fundamental.


Subject(s)
Humans , Aged , Palliative Care/methods , Patient Care Team , Stroke/complications , Stroke/diagnosis , Stroke/therapy , Professional-Family Relations , Prognosis , Terminal Care , Acute Disease , Patient-Centered Care
18.
Arch. cardiol. Méx ; 89(1): 5-11, Jan.-Mar. 2019. tab, graf
Article in English | LILACS | ID: biblio-1038470

ABSTRACT

Abstract Introduction: Carotid disease, measured as carotid intima-media thickness (CIMT) and carotid plaque (CP), is associated with major adverse cardiac and cerebrovascular events (MACCE) in people without the previous atherosclerotic disease; however, there are few published data in patients undergoing coronary angiography. The aim of the study is to determinate if the carotid disease is associated with MACCE after coronary angiography. Methods: A total of 390 consecutive patients underwent coronary angiography after exercise echocardiography and carotid ultrasonography between 2002 and 2013. MACCE was defined as stroke, myocardial infarction due to atherosclerosis progression or death due to a stroke or cardiac event. Results: Two patients were lost (0.5%). During a mean follow-up of 6.0 years (standard deviation of 2.9), 52 patients (13.4%) suffered MACCE. 1, 5, and 10 years, event-free survival was 96.4% (1.0), 88.7% (1.7), and 81.4% (2.8), respectively. Event rates at 10 years were higher in the CP group (23.2% vs. 10.2%, p = 0.013) and in the CIMT > 0.9 mm group (25.9% vs. 13.3%, p = 0.023). Multivariate analysis showed smoking habit (hazard ratio [HR] 2.51, 95% confidence interval [CI] 1.36-4.62, p = 0.003), glomerular filtration rate (HR 0.98, 95% CI 0.98-0.99), aortic stenosis (HR 2.99, 95% CI 1.24-7.21, p = 0.014), incomplete/no coronary revascularization (HR 1.97, 95% CI 1.06-3.67, p = 0.033), insulin treatment (HR 2.63, 95% CI 1.30-5.31, p = 0.006), and CP (HR 2.36, 95% CI 1.02-5.44, p = 0.044) as predictors of MACCE. Conclusions: CP is an independent predictor of MACCE in patients undergoing coronary angiography.


Resumen La enfermedad carotídea, definida como grosor de íntima media (GIMC) y placa (PC), se asocia con eventos adversos cardiacos y cerebrovasculares (EACC) en sujetos sin aterosclerosis previa; sin embargo hay pocos datos en pacientes sometidos a coronariografía. El objetivo del estudio es determinar si la enfermedad carotídea se asocia a EACC en pacientes remitidos a coronariografía Métodos: Entre 2002 y 2013 390 pacientes fueron sometidos a coronariografía tras ecocardiograma de esfuerzo y ecografía carotídea. Se definió EACC como accidente cerebrovascular, infarto de miocardio por progresión aterosclerótica o muerte por accidente cerebrovascular o causa cardiaca. Resultados: Durante un seguimiento medio de 6 años (desviación estándar 2, 9) se registraron 2 pérdidas y 52 eventos (13,4%). La supervivencia media libre de eventos a uno, cinco y diez años fue 96.4% (1.0), 88.7% (1.7) y 81.4% (2.8). Hubo mayor número de eventos a 10 años en el grupo de PC (23.2% frente 10.2%, p = 0.013) y GIMC > 0.9 mm (25,9% frente 13.3%, p = 0.023). En el análisis multivariado los predictores de EACC fueron tabaquismo (hazard ratio [HR] 2.51, intervalo de confianza [IC] al 95% 1.36-4.62, p = 0.003), filtrado glomerular renal (HR 0.98 IC95% 0.98-0.99), estenosis aórtica (HR 2.99, IC 95% 1.24-7.21, p = 0.014), revascularización incompleta/no revascularización (HR 1.97, IC 95% 1.06-3.67, p = 0.033), tratamiento con insulina (HR 2.63, IC 95% 1.30-5.31, p = 0.006) y PC (HR 2.36, 95%CI 1.02-5.44, p = 0.044). Conclusiones: La PC es un predictor independiente de EACC en pacientes sometidos a coronariografía.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Carotid Artery Diseases/complications , Coronary Angiography , Stroke/etiology , Plaque, Atherosclerotic/complications , Myocardial Infarction/etiology , Carotid Artery Diseases/diagnosis , Survival Analysis , Retrospective Studies , Risk Factors , Follow-Up Studies , Disease Progression , Stroke/diagnosis , Stroke/mortality , Myocardial Infarction/diagnosis
19.
Medwave ; 19(6): e7668, 2019.
Article in English, Spanish | LILACS | ID: biblio-1007971

ABSTRACT

Resumen Introducción Las enfermedades cerebrales vasculares son la primera causa específica de muerte y discapacidad en Chile. Objetivo Analizar características epidemiológicas de pacientes hospitalizados con diagnóstico de accidentes vasculares cerebrales en el Complejo Asistencial Víctor Ríos Ruiz. Metodología Estudio observacional, transversal. Se analizaron los egresos hospitalarios con diagnóstico de accidentes vasculares cerebrales entre 2014 y 2017. Se recolectaron datos sobre el diagnóstico de accidentes vasculares cerebrales mediante registro CIE 10, datos demográficos, tipo de accidentes vasculares cerebrales y datos respecto de la letalidad y estadía intrahospitalaria. Las variables cuantitativas fueron expresadas mediante promedios y desviación estándar (± DS) mientras que las variables categóricas fueron evaluadas mediante frecuencias absolutas y relativas. Las diferencias entre las variables fueron analizadas mediante T de Student y ANOVA de un factor. Se consideraron resultados significativos los valores p < 0,05. Resultados Se caracterizó un total de 1856 egresos, 58,6% fueron hombres, edad media de 66,9 (± 13,9) años y estadía media de 10,4 (± 16,7) días. En mujeres, la edad media fue 69,9 (± 16) años y estadía media 11,1 (± 16,5) días. El 55,5% correspondió a accidentes vasculares cerebrales isquémicos y 17,4% accidentes vasculares cerebrales hemorrágicos. Los principales factores de riesgo fueron hipertensión arterial (72%) y diabetes mellitus (33%). La letalidad intrahospitalaria global fue de 10,6%. Tanto la letalidad y estadía prolongada estuvieron asociadas a hemorragia subaracnoidea y accidentes vasculares cerebrales hemorrágicos (valor p < 0,05). Conclusiones La prevalencia de accidentes vasculares cerebrales es similar en hombres y mujeres. La hipertensión arterial fue el factor de riesgo más prevalente. A pesar de que el accidente vascular cerebral isquémico fue el más frecuente, la hemorragia subaracnoidea y el accidente cerebral vascular hemorrágico fueron relacionados con una mayor letalidad y estadía prolongada.


Abstract Introduction Stroke is the leading cause of death and disability in Chile. Objective To analyze the epidemiological characteristics of hospitalized patients with a diagnosis of stroke in our hospital unit (Complejo Asistencial Víctor Ríos Ruiz). Methods We performed an observational, cross-sectional study. We included patients who were discharged from our hospital with a diagnosis of stroke between 2014 and 2017. We extracted data on stroke-related ICD codes, demographic variables, types of stroke, case fatality rates, and hospital stay. Quantitative variables were expressed as averages with standard deviation (± SD), and categorical variables were expressed as absolute and relative frequencies. Differences were analyzed using Student t-distribution and ANOVA. We defined a p-value of < 0.05 as statistically significant. Results In total, 1856 patients were discharged of which 58.6% were male, with an average age of 66.9 (± 13.9) years, and an average stay of 10.4 (± 16.7) days. In the female population, the average age was 69.9 (± 16), and the average hospitalization was 11.1 (± 16.5) days. 55.5% of stroke cases was ischemic, and 17.4% was hemorrhagic. The main risk factors were hypertension (72%) and type 2 diabetes (33%). We found an overall in-hospital case fatality rate of 10.6%. Both the case fatality rate and prolonged in-hospital stay were associated with subarachnoid hemorrhage and hemorrhagic stroke (p < 0.05). Conclusions Prevalence of stroke is similar in both men and women. Hypertension was the leading risk factor associated with acute stroke. Although ischemic stroke was the most frequent diagnosis, both subarachnoid hemorrhage and hemorrhagic stroke were related to an increased case fatality rate and a more extended hospital stay.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Aged, 80 and over , Stroke/epidemiology , Diabetes Mellitus, Type 2/epidemiology , Hospitalization , Hypertension/epidemiology , Subarachnoid Hemorrhage/epidemiology , Chile , Prevalence , Cross-Sectional Studies , Risk Factors , Diagnosis-Related Groups , Stroke/diagnosis , Stroke/etiology , Intracranial Hemorrhages/epidemiology , Length of Stay
20.
Audiol., Commun. res ; 24: e2024, 2019. tab, graf
Article in Portuguese | LILACS | ID: biblio-989408

ABSTRACT

RESUMO Objetivos Identificar estudos que tenham abordado as avaliações do processamento auditivo central, eletrofisiológicas e/ou comportamentais, em crianças e adolescentes acometidos por acidente vascular cerebral. Estratégia de pesquisa Conduziu-se uma busca no mês de julho de 2017, usando os descritores: stroke , auditory perception, childhood, child, children e evoked potentials auditory nas bases de dados PubMed, Scopus e SciELO. Critérios de seleção Foram selecionados artigos em inglês e português, publicados até julho de 2017, sem limitação de data inicial. Os artigos deveriam apresentar abordagem metodológica que referisse achados da avaliação do processamento auditivo central, em crianças e adolescentes com diagnóstico de acidente vascular cerebral. Resultados Inicialmente, foram encontrados 15 estudos, resultando na seleção de três artigos que atendiam aos critérios de inclusão e que foram considerados relevantes para a amostra deste estudo. Devido ao fato de que nenhum dos estudos incluídos tenha utilizado os potenciais evocados auditivos de longa latência em suas avaliações audiológicas, optou-se por realizar uma segunda busca, com os descritores: stroke AND children AND evoked potentials, auditory, nas mesmas bases de dados. Com estes descritores, obteve-se 36 artigos e, destes, apenas um artigo foi selecionado, de acordo com os critérios de inclusão estabelecidos. Conclusão Foram verificados poucos estudos na literatura, que tenham avaliado o processamento auditivo central em crianças e adolescentes acometidos por acidente vascular cerebral. Não obstante, salienta-se a importância dos estudos encontrados para contribuição nos processos de diagnóstico e de monitoramento terapêutico dessa população.


ABSTRACT Purpose To identify studies that have addressed Central Auditory Processing (CAP), through electrophysiological and/or behavioral tests, in children and adolescents affected by Stroke. Research strategy A search was conducted in July 2017, using the descriptors: "stroke ", auditory perception", "childhood ", "child" and " evoked potentials, auditory" in PubMed, Scopus and SciELO databases. Selection criteria Articles written in English, Portuguese and Spanish, published until July 2017, without start date limitation. The articles should present a methodological approach that refers to the findings of central auditory processing assessment in children and adolescents diagnosed with stroke. Results First, 15 studies were found, and three of them were selected because they met the inclusion criteria and were considered relevant for the sample of the present study. As none of the included studies used LLAEP in their audiological assessments, a second search was performed with the descriptors: "stroke" AND " children" AND "evoked potentials, auditory " in the same databases. A total of 36 papers were found with these descriptors but only one paper was selected, according to the established inclusion criteria. Conclusion Few studies in the literature have assessed central auditory processing in children and adolescents with stroke. Nevertheless, the studies are important for diagnos and therap monitoring in this population.


Subject(s)
Humans , Child , Adolescent , Auditory Perception , Stroke/diagnosis , Electrophysiology , Evoked Potentials, Auditory
SELECTION OF CITATIONS
SEARCH DETAIL