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1.
J. bras. psiquiatr ; 70(3): 236-244, jul.-set. 2021. tab
Article in English | LILACS-Express | LILACS | ID: biblio-1350951

ABSTRACT

OBJECTIVE: The executive functions (EF) and emotion regulation (ER) and their relationship with the substance use disorder (SUD) were analyzed. METHODS: A cross-sectional design was used. The sample consisted of 130 volunteers divided into three groups: group 01 (n = 60), composed of participants who did not meet the diagnostic criteria for any type of SUD; group 02 (n = 51), with users with alcohol and/ or tobacco use disorder; group 03 (n = 19), with users with multiple substance use disorder, including at least one illicit substance. RESULTS: Group 02 presented worse performance in EF and ER when compared to group 01, and showed a significant correlation between the working memory and the use of maladaptive ER. Group 03 showed great losses in EF and ER when compared to the other groups. CONCLUSION: This study supports the idea that EF, ER and SUD are related. In addition, it was observed that people with SUD had worse performance in EF and ER when compared to people without SUD, greater damage being observed in people with SUD of polysubstances.


OBJETIVO: Analisaram-se as funções executivas (FE) e a regulação emocional (RE) e a sua relação com o transtorno por uso de substâncias (TUS). MÉTODOS: Utilizou-se um delineamento transversal. A amostra foi composta por 130 voluntários, divididos em três grupos: grupo 01 (n = 60), composto pelos participantes que não preenchiam os critérios diagnósticos para nenhum tipo de TUS; grupo 02 (n = 51), com os entrevistados com TUS de álcool e/ou cigarro; grupo 03 (n = 19), com os voluntários com TUS de polissubstâncias, incluindo pelo menos uma substância ilícita. RESULTADOS: O grupo 02 apresentou pior desempenho nas FE e na RE, quando comparado ao grupo 01, e exibiu uma correlação significativa entre a memória de trabalho e o uso de RE desadaptativa. O grupo 03 apresentou maior prejuízo nas FE e na RE, quando comparado aos demais grupos. CONCLUSÃO: Este estudo apoia a ideia de que as FE, a RE e o TUS estão relacionados. Além disso, observou-se que as pessoas com TUS apresentaram pior desempenho nas FE e na RE, quando comparadas com as pessoas sem o TUS, sendo as com TUS de polissubstâncias com maior prejuízo.


Subject(s)
Humans , Male , Adult , Young Adult , Substance-Related Disorders/complications , Drug Users , Executive Function , Emotional Regulation , Tobacco Use Disorder , Illicit Drugs , Cross-Sectional Studies , Surveys and Questionnaires , Analysis of Variance , Alcohol-Related Disorders/complications , Memory Disorders/etiology
3.
Washington; Organización Panamericana de la Salud; dic. 09, 2020. 18 p. tab..
Non-conventional in English, Spanish | LILACS | ID: biblio-1150960

ABSTRACT

Los eventos que causan un grado de estrés importante, como la pandemia de COVID-19, constituyen un factor de riesgo para la aparición, agudización o recaída de toda una gama de trastornos mentales, neurológicos y por consumo de sustancias psicoactivas, en especial en los grupos de población más vulnerables. En los estudios de ámbito nacional en la Región de las Américas se describe un aumento del desasosiego, la depresión, la ansiedad y el insomnio, entre otros, como resultado de la pandemia de COVID-19. Además, los casos de COVID-19 dan lugar a varias complicaciones neurológicas y mentales.Los eventos que causan un grado de estrés importante, como la pandemia de COVID-19, constituyen un factor de riesgo para la aparición, agudización o recaída de toda una gama de trastornos mentales, neurológicos y por consumo de sustancias psicoactivas, en especial en los grupos de población más vulnerables. En los estudios de ámbito nacional en la Región de las Américas se describe un aumento del desasosiego, la depresión, la ansiedad y el insomnio, entre otros, como resultado de la pandemia de COVID-19. Además, los casos de COVID-19 dan lugar a varias complicaciones neurológicas y mentales. Para comprender la repercusión de la pandemia en los servicios para los trastornos mentales, neurológicos y por consumo de sustancias psicoactivas, la OMS elaboró una encuesta, que fue realizada por la OMS y la OPS y se envió a los puntos focales de salud mental designados para ello en los ministerios de salud de todos los Estados Miembros de la OMS. Este informe utiliza los datos presentados por los Estados Miembros de la OPS en respuesta a la encuesta para presentar un panorama general de la repercusión de la COVID-19 en tales servicios en la Región de las Américas. Esta información será útil para fundamentar la planificación y las respuestas destinadas a atenuar los efectos de la pandemia por los países de la Región.


Major stressors such as the COVID-19 pandemic represent risk factors for the development, exacerbation and relapse of a range of mental, neurological and substance use (MNS) disorders, particularly in the most vulnerable groups. National studies from the Region of the Americas, demonstrate increases in distress, depression, anxiety, and insomnia, among other conditions, as a result of the COVID-19 pandemic. Furthermore, COVID-19 itself is associated with neurological and mental complications. This report is based on the results of a survey, developed by the World Health Organization (WHO) and implemented by the WHO and the Pan American Health Organization (PAHO), which was sent to designated mental health focal points in ministries of health of all WHO Member States. It uses data submitted by PAHO Member States in response to the survey to provide an overview of the impact of COVID-19 on MNS services in the Region of the Americas. This information will help to inform planning and response to mitigate the effects by countries in the Region.


Subject(s)
Humans , Pneumonia, Viral/psychology , Social Isolation/psychology , Mental Health , Immunization Programs/organization & administration , Coronavirus Infections/psychology , Substance-Related Disorders/complications , Pandemics/prevention & control , Mental Disorders/epidemiology , Americas/epidemiology
4.
Rev. Bras. Saúde Mater. Infant. (Online) ; 20(1): 313-317, Jan.-Mar. 2020. tab, graf
Article in English | LILACS, SES-SP | ID: biblio-1136409

ABSTRACT

Abstract Objectives: evaluate changes in the use of psychoactive substances (PAS) throughout pregnancy. Methods: longitudinal study, with pregnant women users of PAS at a prenatal follow-up. Results: 76 pregnant women used: tobacco (84.2%, n=64), alcohol (73.7%, n=56), cocaine (27.6%, n=21), marijuana (26.3%, n=20) and crack (13.1%, n=10). Spontaneous interruption had occurred in 60% (n=6) of crack users, 57.1% (n=12) of cocaine and 50% (n=28) of alcohol. After the Brief Intervention, 78.9% (15 of the total of 19) of alcohol users and 70% (7 of the total of 10) of marijuana users discontinued the consumption and there was a reduction in smoking cigarettes. Conclusions: the spontaneous reduction in the consumption of PAS and after the interventions, pregnancy is a window of opportunity to reduce the use of drugs.


Resumo Objetivos: avaliar mudanças no uso de substâncias psicoativas (SPA) durante a gravidez. Métodos: estudo longitudinal, com gestantes usuárias de SPA em seguimento pré-natal. Resultados: 76 gestantes, que utilizavam: tabaco (84,2%, n=64), álcool (73,7%, n=56), cocaína (27,6%, n=21), maconha (26,3%, n=20) e crack (13,1%, n=10). Houve interrupção espontânea em 60% (n=6) das usuárias de crack, 57,1% (n=12) de cocaína e 50% (n=28) de álcool. Após Intervenção Breve, cessaram o consumo 78,9% (15 do total de 19) das usuárias de álcool e 70% (7 do total de 10) de maconha, e as tabagistas diminuíram o número de cigarros. Conclusões: a redução do consumo de SPA espontânea e após intervenções reforçam a gravidez como janela de oportunidade para abordagem do uso de drogas.


Subject(s)
Humans , Female , Pregnancy , Pregnancy Complications , Prenatal Care , Psychotropic Drugs , Illicit Drugs , Pregnancy, High-Risk , Substance-Related Disorders/complications , Crisis Intervention , Smoking Reduction , Alcohol Drinking , Marijuana Smoking , Longitudinal Studies , Crack Cocaine , Cocaine , Maternal-Child Health Services
5.
Medwave ; 20(2): e7853, 31-03-2020.
Article in English, Spanish | LILACS | ID: biblio-1095856

ABSTRACT

INTRODUCCIÓN: La Unidad de Corta Estadía Infanto-juvenil del Hospital Psiquiátrico del Salvador (Valparaíso, Chile) y sus pacientes poseen características clínicas y sociales diferentes a las reportadas por la escasa literatura nacional al respecto. OBJETIVOS: Describir el funcionamiento la unidad, las características sociofamiliares y clínicas de sus pacientes y analizar los factores asociados a su evolución clínica. MÉTODOS: Estudio transversal que describió el universo de pacientes hospitalizados durante tres años. Las variables se recogieron desde una base de datos anonimizada. Se evaluó la evolución clínica dentro del año posterior al egreso hospitalario. RESULTADOS: El modelo de atención de la unidad presenta los componentes biomédico, psicodinámico y ecológico. Se analizaron 98 pacientes, 70,4% hombres, con edad promedio de 11,5 ± 2,3 años. Un 82,6% perteneció al nivel socioeconómico bajo y 35,7% estaba desescolarizado; 98,9% presentó disfunción familiar y 91,8% de los padres portaba alguna psicopatología. Los motivos de ingreso más frecuente fueron riesgo de hetero y autoagresión. Los diagnósticos de egreso más frecuente fueron trastornos de conducta, depresivos y del desarrollo de la personalidad. El tiempo de estadía promedio fue de 41,8 ± 31,1 días. Los fármacos más utilizados fueron antipsicóticos y estabilizadores del ánimo. Un 47% tuvo una buena evolución clínica, 27% regular y 26% insatisfactoria. El único factor que se asoció a esta última fue haber tenido prescrito un antidepresivo durante la hospitalización. El factor que consistentemente se vinculó al reingreso a lo largo de un año, fue el haber presentado trastorno por consumo de sustancias. El abandono a tratamiento se relacionó con haber presentado un trastorno de conducta al egreso hospitalario y a tener padres con antecedente de suicidio o suicidio consumado. CONCLUSIONES: El perfil de pacientes de esta unidad corresponde a pacientes de nivel socioeconómico bajo, psicopatología severa, conducta desadaptativa, disfunción familiar y frecuente psicopatología parental. El trastorno por consumo de sustancias es un factor significativamente asociado al reingreso hospitalario.


INTRODUCTION: Patients of the Short-stay Child and Adolescent Unit of the Del Salvador Psychiatric Hospital (Valparaíso, Chile) exhibit different clinical and social characteristics compared to literature reports of other national centers, although published data are scarce. OBJECTIVES: To describe the operation of the Unit, the socio-familial and clinical characteristics of its patients and analyze factors associated with their clinical evolution. METHODS: We performed a cross-sectional study to describe the patients hospitalized over a three-year period. Variables were registered in an anonymized database. Clinical evolution was evaluated over the year following hospital discharge. RESULTS: The Unit's model of care can be described as involving biomedical, psychodynamic, and ecological components. We included 98 patients, of which 70.4% were male, and the average age was 11.5 ± 2.3 years. 82.6% were of low socioeconomic status, and 35.7% did not attend school; 98.9% presented family dysfunction, and 91.8% of parents had a history of psychopathology. The most frequent reason for admission was the risk of harm to self or others. The most frequent discharge diagnoses were behavioral, depressive, and personality development disorders. The average length of stay was 41.8 ± 31.1 days. The most commonly used pharmacological agents were antipsychotics and mood stabilizers. Regarding clinical evolution in the first year post-discharge, 47% were evaluated as positive, 27% regular, and 26% unsatisfactory. The factor associated with an unsatisfactory clinical course was having had in-patient antidepressants. Re-admission during the first year post-discharge was associated with comorbid substance use disorder. Treatment noncompliance was associated with a history of behavioral disorder at hospital discharge and having parents with a history of suicide or consummated suicide. CONCLUSIONS: The patient profile is one of low socioeconomic status, severe psychopathology, maladaptive behavior, family dysfunction, and parental psychopathology. Substance use disorder is also associated with readmission.


Subject(s)
Humans , Male , Female , Child , Adolescent , Substance-Related Disorders/complications , Hospitalization , Mental Disorders/complications , Mental Disorders/psychology , Mental Disorders/therapy , Patient Readmission , Suicide , Antipsychotic Agents , Family , Chile , Cross-Sectional Studies , Hospitals, Psychiatric
6.
Ciênc. Saúde Colet ; 24(12): 4707-4716, dez. 2019. tab
Article in Spanish | LILACS | ID: biblio-1055739

ABSTRACT

Resumen Esta etnografía se realizó en Barcelona, ciudad que ofrece diferentes recursos de ocio homosexual, como las saunas gay. El objetivo fue analizar desde los estudios sobre género y masculinidades, cómo se articula la sexualidad, la percepción sobre la infección por VIH y otras infecciones de transmisión sexual (ITS), y las medidas preventivas en trabajadores sexuales masculinos (TSM) usuarios de saunas gay. Se realizaron 10 entrevistas en profundidad y observación entre 2012 y 2016. Las prácticas de sexo seguro son más frecuentes con clientes, mientras que las de riesgo se realizan más con parejas no comerciales. La orientación sexual juega un rol relevante, los homosexuales asumen más prácticas de riesgo en el trabajo sexual que los heterosexuales. Consumo de drogas o la escasez de redes de apoyo se relacionaron con mayor vulnerabilidad social y conductas de riesgo. Contraer el VIH aún genera miedo, mientras que tener otras ITS se percibe como parte de la vida sexual de un hombre. El TSM afianza una masculinidad con múltiples parejas sexuales, breadwinner y por otra parte, cuestiona un modelo heteronormativo. Las intervenciones para la prevención del VIH e ITS en este colectivo, deberían considerar los determinantes sociales como las precarias alternativas laborales y el ofrecer mayor soporte social.


Abstract This ethnography was conducted in Barcelona, a city that provides different gay leisure resources, such as gay saunas. We aimed to analyze from studies on gender and masculinities, how sexuality, perception of HIV infection and other sexually transmitted infections (STIs), and preventive measures are articulated in gay sauna male sex workers (MSW). Ten in-depth interviews and observation were conducted between 2012 and 2016. Safe sex practices are more frequent with clients, while risk practices are carried out more with non-commercial partners. Sexual orientation plays an important role. Homosexuals assume riskier practices in sex work than heterosexuals. Drug use or lack of support networks were associated with higher social vulnerability and risk behaviors. Contracting HIV still creates fear, while having other STIs is perceived as part of a man's sexual life. The MSW affirms masculinity with concurrent sexual partners, breadwinner, and on the other hand, questions a heteronormative model. Interventions for the prevention of HIV and STIs in this group should consider social determinants such as inferior work alternatives and the provision of more significant social support.


Subject(s)
Humans , Male , Adult , Young Adult , Steam Bath , Sexually Transmitted Diseases/prevention & control , Safe Sex/psychology , Unsafe Sex/psychology , Masculinity , Sex Workers/psychology , Social Support , Spain , Sexually Transmitted Diseases/transmission , HIV Infections/prevention & control , HIV Infections/transmission , Homosexuality, Male , Heterosexuality , Substance-Related Disorders/complications , Qualitative Research , Interpersonal Relations , Anthropology, Cultural
7.
Rev. bras. enferm ; 72(6): 1692-1698, Nov.-Dec. 2019. tab
Article in English | LILACS, BDENF | ID: biblio-1042179

ABSTRACT

ABSTRACT Objective: To evaluate the relation between the consumption of alcohol and other drugs and school absenteeism in high school students of public schools in the 30 days prior to data collection. Method: Cross-sectional study of quantitative character conducted from May to September 2017, with 282 high school students of public schools of Mossoró-RN. We used a closed questionnaire with questions about drug consumption as our instrument of analysis. We performed hierarchical binary logistic regression by using the SPSS 20.0. Results: In bivariate analysis, the relation between absenteeism and drug consumption patterns proved to be significant to those who engage in heavy episodic drinking of alcohol and in the use of tobacco, inhalants and marijuana. The adjusted regression model only included the variables tobacco and heavy episodic drinking of alcohol. Conclusion: The hierarchical binary logistic regression analysis corroborated with absenteeism outcomes, explaining it in 12.3% of cases.


RESUMEN Objetivo: Evaluar la relación entre el consumo de alcohol y de otras drogas y el absentismo escolar en estudiantes de la enseñanza media pública durante 30 días anteriores a la recolección de datos. Método: Estudio transversal, cuantitativo, realizado entre mayo y septiembre de 2017, en el cual participaron 282 adolescentes, estudiantes de escuelas públicas de enseñanza media de la ciudad de Mossoró (RN, Brasil). Se utilizó un cuestionario cerrado con preguntas sobre el consumo de drogas. Se realizó una regresión logística binaria jerarquizada con el auxilio del SPSS 20.0. Resultados: En el análisis bivariado, la relación entre el absentismo escolar y los patrones de consumo de drogas se mostró significativa para quienes tenían un consumo excesivo episódico de alcohol y un consumo de tabaco, de inhalantes y de marihuana. El modelo de regresión ajustado incluyó solamente las variables consumo excesivo episódico de alcohol y consumo de tabaco. Conclusión: El análisis de la regresión logística binaria jerarquizada se mostró ajustada para el resultado del absentismo escolar, lo que explica el 12,3% de los casos.


RESUMO Objetivo: Avaliar a relação do consumo de álcool e outras drogas com o absenteísmo escolar em estudantes do ensino médio público nos 30 dias anteriores à coleta. Método: Estudo transversal, quantitativo, realizado de maio a setembro de 2017, com 282 adolescentes, estudantes de escolas públicas de ensino médio de Mossoró-RN. Utilizou-se um questionário fechado com questões sobre o uso de drogas. Realizou-se regressão logística binária hierarquizada com o apoio do SPSS 20.0. Resultados: Na análise bivariada, a relação entre o absenteísmo escolar e os padrões de consumo de drogas se mostrou significativa para aqueles com prática de beber pesado episódico de álcool e uso de tabaco, inalantes e maconha. O modelo de regressão ajustado incluiu apenas as variáveis beber pesado episódico de álcool e tabaco. Conclusão: A análise da regressão logística binária hierarquizada se mostrou ajustada para o desfecho do absenteísmo escolar, explicando-o em 12,3% dos casos.


Subject(s)
Humans , Male , Female , Adolescent , Alcohol Drinking/adverse effects , Substance-Related Disorders/complications , Absenteeism , Schools/organization & administration , Schools/statistics & numerical data , Students/psychology , Students/statistics & numerical data , Brazil , Alcohol Drinking/psychology , Cross-Sectional Studies , Surveys and Questionnaires , Substance-Related Disorders/psychology
8.
J. oral res. (Impresa) ; 8(5): 378-385, oct. 31, 2019. tab, ilus
Article in English | LILACS, BNUY, BNUY-Odon | ID: biblio-1248139

ABSTRACT

Objective: to determine the oral health status perception of adolescents and young adults in drug dependence treatment. Material and Method: a qualitative research model was proposed. The theoretical sample by saturation consisted of adolescent population and young adults hospitalized in the Portal Amarillo center (the National Drug Information and Reference Center, Montevideo, Uruguay). Inclusion criteria: a) being between 15 and 24 years old. b) being in treatment for drug abuse. Exclusion criteria: a) non-lucid patients. b) non-collaborating patients. Results: participants considered oral health as having clean, white and aligned teeth; and oral disease as the presence of caries, bleeding gums and communicable diseases; chewing, aesthetics and taste were seen as altered functions. Before becoming drug consumers, oral hygiene was regular, after meals and as instructed; once addiction began, hygiene was very irregular at best (if they remember to do it), and without reinforcement of the instruction. Prior to drug consumption, participants were students or held a job; they had a good family life, with a partner or in search of one. After consumption, they report self-marginalization, loss of contact with partners and children, isolation from the family and social discrimination. Addiction makes it difficult for them to access dental care, except in urgent situations. Conclusions: Young people in treatment for drug dependence are aware that addiction damages oral health, deteriorating aesthetics, affecting oral functions, self-esteem and quality of life.


Objetivo: conocer la percepción de adolescentes y adultos jóvenes vinculados al consumo abusivo de drogas a partir de la situación de dependencia. Materiales y Métodos: se planteó un modelo de investigación cualitativo. La muestra teórica por saturación fue población adolescente y adulta joven que se asistió en régimen de internación en el Portal Amarillo. Criterios de inclusión: a) tener entre 15 y 24 años. b) estar en tratamiento por consumo de drogas. Criterios de exclusión: a) pacientes no lúcidos. b) pacientes no colaboradores. Resultados: los participantes refieren como salud bucal tener los dientes limpios, blancos y alineados; como enfermedad caries, sangrado de encías y enfermedades transmisibles; y como funciones alteradas la masticación, la estética y el gusto. Antes de la situación de dependencia la higiene bucal era regular, después de las comidas y con instrucción recibida, a partir de la dependencia la higiene fue muy irregular, si se acordaban y sin refuerzo de la instrucción. Previo al consumo eran individuos integrados al estudio o al trabajo, con vida familiar ordenada, con pareja o en procura de tenerla; posteriormente al consumo relatan automarginación con pérdida de contacto con la pareja e hijos, aislamiento de la familia y discriminación social. El consumo dificulta el acceso a la atención odontológica, excepto en situaciones de urgencia. Conclusion: Las personas jóvenes en tratamiento por dependencia a las drogas perciben el deterioro de su salud bucal a partir de la situación de consumo, alterando la estética, las funciones orales, la autoestima y la calidad de vida.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Young Adult , Oral Health , Substance-Related Disorders/complications , Oral Hygiene , Perception , Uruguay , Dental Health Surveys , Risk Factors
10.
Rev. chil. infectol ; 36(3): 331-339, jun. 2019. tab, graf
Article in Spanish | LILACS | ID: biblio-1013791

ABSTRACT

Resumen Introducción: El tratamiento anti-retroviral (TAR) es indispensable en pacientes con infección por VIH/ SIDA; suprimir la carga viral requiere de un estricto apego a éste, por compromiso del paciente. El fracaso del TAR es primordialmente por falta de adherencia, que puede ser debida a una deficiente calidad de vida y/o a variables psicológicas. Objetivo: Determinar la calidad de vida, variables psicológicas y la adherencia al TAR, en pacientes con infección por VIH/SIDA. Material y Método: Se incluyeron 160 pacientes con diagnóstico de infección por VIH/SIDA y con TAR. Se recabaron los instrumentos MOS SF-36 y VPAD-24, una encuesta demográfica, y datos clínicos. Se hicieron asociaciones cuantitativas y cualitativas entre las variables. Resultados: La adherencia al TAR estuvo asociada con evitar comportamiento depresivo y con ausencia de adicciones. El comportamiento depresivo se encontró asociado con las adicciones. Un 87% de pacientes estaba en el rango de mejor calidad de vida. Por debajo del promedio del puntaje de salud general estuvieron masculinos, con orientación sexual HSH, solteros, en la vitalidad a los ≥ 38 años, en dolor corporal y función social a tres esquemas TAR. Conclusión: La buena adherencia al TAR estuvo asociada a evitar comportamiento depresivo y a la ausencia de adicciones y no se asoció a la calidad de vida.


Background: Antiretroviral treatment (ART) is essential in HIV/AIDS patients. Suppressing viral load requires strict adherence to ART in addition to the patient's commitment to treatment. The failure of ART is mainly due to lack of adherence, which may in turn be due to poor quality of life and/or to psychological variables. Aim: To determine the quality of life and psychological variables and adherence to ART, in patients with HIV/AIDS. Material and Method: 160 patients diagnosed with HIV/AIDS and with ART were included. The MOS SF-36 and VPAD-24 instruments, a socio-demographic survey, and clinical data were collected. Quantitative and qualitative associations were made between the variables. Results: The adherence to ART was associated with avoidance of depressive behavior and with the absence of addictions. Depressive behavior associated with addictions. 87% of patients ranked in the best quality of life. Below the average of the general health score were males, with MSM sexual orientation, single, in vitality at ≥ 38 years, in corporal pain and with social function to three ART schemes. Conclusion: Good adherence to ART was associated with avoiding depressive behavior and with non-addictions and not associated with quality of life.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Quality of Life/psychology , Acquired Immunodeficiency Syndrome/psychology , Antiretroviral Therapy, Highly Active/psychology , Medication Adherence/psychology , Sexual Behavior/psychology , Socioeconomic Factors , Cross-Sectional Studies , Surveys and Questionnaires , Acquired Immunodeficiency Syndrome/complications , Acquired Immunodeficiency Syndrome/drug therapy , Substance-Related Disorders/complications , Anti-Retroviral Agents/therapeutic use , Depression/complications , Depression/psychology , Mexico
12.
Rev. Soc. Bras. Med. Trop ; 52: e20180064, 2019. tab, graf
Article in English | LILACS | ID: biblio-1041582

ABSTRACT

Abstract INTRODUCTION: Female sex workers (FSWs) are considered a bridge for transmission of pathogens from high-risk to general populations. We assessed the epidemiological status of syphilis in FSWs along the Pará highway system. METHODS: Two hundred and twenty-two FSWs were interviewed and samples were analyzed using rapid qualitative tests and real-time polymerase chain reaction. RESULTS: The prevalence of syphilis was high (36.94%). The high rate of prostitution, use of illicit drugs, and search for financial resources increased Treponema pallidum transmission through unprotected sex. CONCLUSIONS: Several characteristics of FSWs were identified, which reinforce the need for measures guaranteeing their health and protection.


Subject(s)
Humans , Female , Adult , Young Adult , Syphilis/epidemiology , Sex Workers/statistics & numerical data , Socioeconomic Factors , Transportation , Treponema pallidum/genetics , Brazil/epidemiology , Syphilis/diagnosis , Syphilis/transmission , Prevalence , Cross-Sectional Studies , Risk Factors , Substance-Related Disorders/complications , Unsafe Sex , Real-Time Polymerase Chain Reaction , Middle Aged
13.
Braz. oral res. (Online) ; 33: e031, 2019. tab, graf
Article in English | LILACS | ID: biblio-1039304

ABSTRACT

Abstract: Variable rates of HPV infection have been reported in healthy oral mucosa worldwide. The main objective of this study was to detect and genotype HPV infection in users and nonusers of drugs with clinically healthy mucosa from the Northeast Brazil. Samples from 105 patients were amplified using the primers MY09/MY11 and GP5+/GP6+, and genotyping was performed by multiplex-PCR for HPV-6/11, 16 and 18. A total of 81.9% samples were positive. Among drug users, 84.5% presented the virus and 20.4% showed multiple infections. Among non-drug users, 78.7% were positive and 13.5% had multiple infections. Limited information is available on oral HPV in Brazilian population, especially for drug users, and our results showed higher HPV infection rates in both users and nonusers of drugs. More studies and researches focused on drug users including factors like sexual behavior, nutrition and cultural habits are necessary to enhance the comprehension of this relationship, and develop preventive strategies.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Young Adult , Substance-Related Disorders/complications , Substance-Related Disorders/virology , Papillomavirus Infections/etiology , Papillomavirus Infections/epidemiology , Mouth Mucosa/virology , Papillomaviridae/isolation & purification , Risk-Taking , Sexual Behavior , Socioeconomic Factors , Brazil/epidemiology , DNA, Viral , Case-Control Studies , Polymerase Chain Reaction , Prevalence , Cross-Sectional Studies , Prospective Studies , Risk Factors , Sex Distribution , Age Distribution , Risk Assessment , Middle Aged
14.
Rev. bras. epidemiol ; 22(supl.1): e190009, 2019. tab, graf
Article in English | LILACS | ID: biblio-1042215

ABSTRACT

ABSTRACT Introduction: Knowledge about risky sexual behavior among young people has been widely acknowledged as a key tool to controlling the spread of HIV. This article aimed at presenting the risk behavior of Brazilian Army conscripts toward HIV infection according to the country's geographic regions. . Method: We collected data from 37,282 conscripts, aged 17 to 22, during enlistment in the Brazilian Army in 2016. The prevalence of HIV infection, both self-reported and measured through laboratory results, and risk behavior factors were estimated by region. Results: 75% of the sample of conscripts reported to have already started sexual activity, and the average age of their sexual initiation was 15. Condom use varied according to the type of sexual relationship, being lower among steady partners and greater among less stable relationships. HIV prevalence assessed by laboratory tests was 0.12% across the country and the highest prevalence was observed in the North region (0.24%). Alcohol and illicit drug usage was higher in the South region. Discussion: The study allowed the observation of risk behavior monitoring for HIV infection among young Brazilians. Lower condom usage among steady partners may be contributing to an increase in the number of HIV-infected individuals. Conclusion: Results suggest the need to intensify prevention campaigns to disseminate safe sex practices among young people, in addition to the expansion of testing offer to this population.


RESUMO Introdução: O conhecimento do comportamento sexual de risco entre jovens tem sido amplamente reconhecido como ferramenta-chave para controlar a propagação do HIV. Este artigo tem o objetivo de retratar o comportamento de risco dos conscritos do Exército brasileiro à infecção pelo HIV segundo as macrorregiões brasileiras. Métodos: Foram utilizados dados de 37.282 conscritos, entre 17 e 22 anos, durante apresentação ao Exército em 2016. Estimaram-se as prevalências de HIV autorreferida e medida por exame laboratorial, além de indicadores de comportamento de risco, por macrorregiões geográficas. Resultados: Dos conscritos que compuseram a amostra, 75% relatou já ter iniciado atividade sexual, e a média de idade de início foi de aproximadamente 15 anos. O uso do preservativo variou de acordo com o tipo de parceria sexual, sendo menor na relação com parceiros(as) fixos(as) e maior nas parcerias menos estáveis. A prevalência da infecção pelo HIV medida através do diagnóstico laboratorial foi de 0,12% no Brasil, sendo mais prevalente na região Norte (0,24%). O consumo de álcool e drogas ilícitas foi maior na região Sul. Discussão: O estudo permitiu observar o monitoramento do comportamento de risco à infecção pelo HIV entre os jovens brasileiros. O menor uso de preservativo quando a parceria sexual é considerada estável pode estar contribuindo para aumentar o número de indivíduos infectados pelo HIV. Conclusão: Os resultados sugerem a necessidade de campanhas de divulgação para os jovens sobre práticas de sexo seguro, além da ampliação da oferta de testagem nessa população.


Subject(s)
Humans , Male , Adolescent , Adult , Young Adult , HIV Infections/etiology , Health Risk Behaviors , Military Personnel/statistics & numerical data , Sexual Behavior/statistics & numerical data , Brazil/epidemiology , Alcohol Drinking/adverse effects , Alcohol Drinking/epidemiology , HIV Infections/epidemiology , Prevalence , Cross-Sectional Studies , Risk Factors , Condoms/statistics & numerical data , Risk Assessment , Substance-Related Disorders/complications , Substance-Related Disorders/epidemiology , Geography
15.
Article in Spanish | LILACS, BINACIS | ID: biblio-1048475

ABSTRACT

La rotura bilateral y simultánea del tendón cuadricipital es una lesión rara con pocos reportes en la literatura, que suele ocurrir en mayores de 50 años con enfermedades sistémicas crónicas subyacentes. Presentamos el caso de un paciente masculino sano de 32 años con rotura bilateral de tendón cuadricipital durante la práctica de musculación asociada a la administración de anabolizantes esteroideos y el tratamiento realizado


Bilateral and simultaneous rupture of the quadriceps tendon is a rare injury with a few reports in record that usually occurs in people older than 50 years with underlying chronic systemic diseases. We present the case of a healthy 32-year-old male patient with bilateral quadriceps tendon rupture during weight training practice associated to anabolic steroids administration and the treatment provided


Subject(s)
Adult , Tendon Injuries/surgery , Substance-Related Disorders/complications , Quadriceps Muscle/injuries , Anabolic Agents/adverse effects , Knee Injuries/pathology , Rupture , Weight Lifting/injuries
16.
São Paulo; s.n; s.n; 2019. 130 p. ilus, graf.
Thesis in Portuguese | LILACS | ID: biblio-998563

ABSTRACT

Uma das principais dificuldades enfrentadas na dependência à cocaína está relacionada aos sintomas de abstinência, como ansiedade, desejo e irritabilidade. Estes efeitos podem durar meses ou anos após a interrupção do consumo prolongado, fazendo com que o indivíduo volte a procurá-la. Os efeitos recompensadores da cocaína levam a alterações neurobiológicas do sistema mesocorticolímbico dopaminérgico, que se origina na área tegmental ventral e se projeta para o núcleo accumbens, e córtex pré-frontal, áreas intimamente ligadas ao desenvolvimento da dependência. Esses neurônios dopaminérgicos recebem estímulos dos neurônios colinérgicos que contribuem para os aspectos cognitivos da dependência. Devido à complexidade neurobilógica envolvida durante a abstinência, pouco se sabe sobre as alterações no sistema colinérgico muscarínico durante este período no encéfalo, objetivo deste estudo. Para tal, camundongos machos adultos Swiss-Webster foram submetidos à cocaína em padrão agudo em binge (3×30 mg/kg/dia) e cronicamente por escalonamento de dose em binge por 14 dias (3×15 mg/kg/dia nos dias 1-4; 3×20 mg/kg/dia nos dias 5-8; 3×25 mg/kg/dia nos dias 9-12; e 3×30 mg/kg/dia nos dias 13 e 14). A atividade locomotora de cada animal foi avaliada em campo aberto (CA), onde permaneceram no aparato por 60 minutos entre cada administração. Após o período de exposição os animais permaneceram 14 dias em abstinência, a fim de avaliar a ansiedade no labirinto em cruz elevado (LCE). Em seguida os animais foram eutaniasiados, sendo o córtex pré-frontal (CPF), o estriado e o hipocampo dissecados e armazenados a -80ºC para a análise dos receptores dopaminérgicos D1 e D2, receptores colinérgicos muscarínicos M1, M2, M3, M4 e M5 (mAChRs) e moléculas colinérgicas (acetilcolinesterase, AChE; colina acetiltransferase, ChAT e transportador vesicular de acetilcolina, VAChT) por Western Blotting (n=6). Os resultados comportamentais mostraram maior atividade locomotora nos animais tratados com cocaína no tratamento agudo ou crônico, quando comparado ao basal. Mais ainda, a sensibilização comportamental foi detectada a partir do segundo dia de administração de cocaína. No teste de LCE, realizado 14 dias após a interrupção da administração de cocaína, não foi observada diferença estatística entre os animais previamente expostos à cocaína e grupo controle. No CPF observou-se diminuição de D2R, M1 mAChRs e aumento M2 e M4 mAChRs no tratamento agudo; no tratamento crônico houve diminuição de M1 e M5 mAChRs e ChAT. No estriado observou-se aumento de D1R, M1 e M2 mAChRs, ChAT no tratamento agudo; e aumento D1R, VAChT, ChAT e diminuição D2R, M1 e M2 mAChRs no tratamento crônico. Já no hipocampo observou-se aumento de D1R, D2R, M2 mAChRs, VAChT e diminuição M1 mAChRs no tratamento agudo; e aumento de D1R, VAChT e diminuição D2R, M1 mAChRs no tratamento crônico. Nossos resultados mostram envolvimento de processo de neuroplasticidade, tanto no sistema dopaminérgico quanto no colinérgico muscarínico, em ambos os protocolos utilizados, mesmo após 14 dias de abstinência


Una de las dificultades enfrentadas en la dependencia de cocaína son los síntomas de abstinencia, como ansiedad, deseo y irritabilidad. Estos efectos pueden durar meses o años después de la interrupción del consumo prolongado, haciendo que el individuo vuelva a consumirlo. Los efectos recompensadores de la cocaína causa alteraciones neurobiológicas del sistema mesocorticolímbico dopaminérgico, que se origina en el área tegmental ventral y se proyecta hacia el núcleo accumbens y córtex pré-frontal, áreas íntimamente ligadas al desenvolvimiento de la dependencia. Esas neuronas dopaminérgicas reciben estímulos de neuronas colinérgicas la cual contribuyen para los aspectos cognitivos de la dependencia. Debido a la complejidad neurobiológica involucrada durante la abstinencia, poco se sabe sobre las alteraciones del sistema colinérgico muscarínico durante este periodo en el encéfalo, objetivo de este estudio. Por tanto, ratones adultos macho Swiss-Webster fueron sometidos a cocaína en dosis padrón agudo en binge (3×30 mg/kg/día) y crónicamente por escalonamiento de dosis en binge por 14 días (3×15 mg/kg/día en los días 1-4; 3×20 mg/kg/día en los días 5-8; 3×25 mg/kg/día en los días 9-12; y 3×30 mg/kg/día en los días 13 e 14). La actividad locomotora de cada animal fue evaluada en el test de campo abierto (CA), donde permanecieron por 60 minutos entre cada administración. Después del periodo de exposición los animales permanecieron 14 días de abstinencia, a fin de evaluar la ansiedad en el labirinto de cruz elevado (LCE). En seguida los animales fueron eutanasiados, donde el córtex pré-frontal (CPF), estriado y hipocampo fueron disecados y almacenados a -80ºC para analizar los receptores dopaminérgicos D1 e D2, receptores colinérgicos muscarínicos M1, M2, M3, M4 y M5 (mAChRs) y moléculas colinérgicas (acetilcolinesterasa, AChE; colina acetiltransferasa, ChAT y transportador vesicular de acetilcolina, VAChT) por Western Blotting (n=6). Los resultados comportamentales mostraron mayor actividad locomotora en los animales tratados con cocaína en tratamiento agudo y crónico, comparado al control. Por otra parte, la sensibilización comportamental fue detectado a partir de segundo día de administración de cocaína. En la prueba de LCE, realizado después de 14 días de interrupción de la administración de cocaína, no fue observado diferencia estadística entre los animales previamente expuestos a la cocaína y el grupo control. En CPF se observó disminución de D2R, M1 mAChRs y aumento de M2 y M4 mAChRs en tratamiento agudo; en el tratamiento crónico mostro disminución de M1 y M5 mAChRs y ChAT. En el estriado se observó aumento de D1R, M1 y M2 mAChRs, ChAT en el tratamiento agudo; aumento D1R, VAChT, ChAT y disminución de D2R, M1 y M2 mAChRs en el tratamiento crónico. Por último, en el hipocampo se observó aumento de D1R, D2R, M2 mAChRs, VAChT y disminución M1 mAChRs en el tratamiento agudo; aumento de D1R, VAChT y disminución D2R, M1 mAChRs en el tratamiento crónico. Nuestros resultados muestran envolvimiento de procesos de neuroplasticidad, tanto en el sistema dopaminérgico como el sistema colinérgico muscarínico, en ambos protocolos utilizados, después de 14 días de abstinencia


Subject(s)
Animals , Male , Mice , Substance Withdrawal Syndrome/drug therapy , Receptors, Cholinergic/analysis , Cocaine/adverse effects , Cholinergic Agents/analysis , Anxiety/classification , Brain/abnormalities , Receptors, Dopamine , Substance-Related Disorders/complications
17.
Psiquiatr. salud ment ; 35(3/4): 244-252, jul.-dic. 2018.
Article in Spanish | LILACS | ID: biblio-1005048

ABSTRACT

Se presenta el caso de un paciente de 53 años que padece dos cuadros clínicos, un trastorno por consumo de sustancia (TUS) y un cuadro de depresión mayor con riesgo suicida lo cual en la actualidad se denomina patología dual. Se dedican dos sesiones a la evaluación diagnóstica y funcional y el tratamiento se desarrolla de manera individual y grupal. Se utilizan técnicas de corte cognitivo-conductual: psicoeducación, mindfulness, técnicas cognitivas y de detección del pensamiento o también llamadas de bloqueo. Tras las sesiones de tratamiento los niveles de craving disminuyen, implementa técnicas de bloqueo y cesa el consumo de alcohol y tabaco. Se mantienen sesiones de seguimiento mensual, que tiene por finalidad objetivar el mantenimiento de los logros terapéuticos. Se observa a lo largo de estas sesiones de seguimiento la remisión de total del consumo de alcohol, tabaco y depresión. Se sigue trabajando actualmente en la búsqueda de actividades placenteras que llenen su tiempo libre (uso adecuado de su tiempo libre).


We present the case of a 53-year-old patient who suffers two clinical disorders, a disorder for consumption of substance and a major depression with suicidal risk, which at present is named a dual pathology. We dedicate two sessions to the diagnostic and functional evaluation and the treatment develops in an individual way and grupal. We use cognitive - behavioral technologies: psychoeducation, mindfulness, cognitive technologies and of thought detection or blockade. After the treatment sessions the levels of craving diminish, we implement technologies of blockade, and patient stops the consumption of alcohol and tobacco. There are kept meetings of monthly follow-up, which has for purpose the maintenance of the therapeutic achievements. Is observed along these meetings of follow-up the total remission of the consumption of alcohol, tobacco, and of depression. We continue working nowadays at the search of pleasant activities that fill his free time (suitable use of his free time).


Subject(s)
Humans , Male , Middle Aged , Substance-Related Disorders/diagnosis , Substance-Related Disorders/therapy , Depression/diagnosis , Depression/therapy , Tobacco Use Disorder , Alcohol Drinking , Cognitive Behavioral Therapy , Diagnosis, Dual (Psychiatry) , Substance-Related Disorders/complications , Depression/complications , Mindfulness
18.
Psiquiatr. salud ment ; 35(3/4): 262-267, jul.-dic. 2018.
Article in Spanish | LILACS | ID: biblio-1005052

ABSTRACT

Caso Clínico: Mujer, 23 años. Discapacidad intelectual. Asiste a colegio especial (no lee ni escribe). Institucionalizada. Motivo de ingreso: Paciente ingresa en octubre del 2017 traída por carabineros por ser encontrada en la calle bajo el efecto de múltiples sustancias, con ideación suicida. Días antes fue expulsada del hogar por agresión a cuidadoras. Diagnósticos de ingreso: Discapacidad intelectual moderado. Síndrome suicidal, Trastorno por dependencia a drogas. ¿Esquizofrenia hebefrénica? Evolución: Mantiene desajustes conductuales severos fluctuantes, con serias dificultades para manejar la rabia, lo que la lleva a tener conductas hetero y autoagresivas. Plan de tratamiento: Farmacológico (clozapina), Psicológico (TCC), Social (dispositivo adecuado post-alta). Clozapina para trastornos psicóticos en adultos con discapacidad intelectual. El principal riesgo de atribuir alguno de estos comportamientos a una supuesta "psicosis", es el de "medicalizar" y tratar de forma poco acertada. Es importante descartar factores ambientales y del aprendizaje (hábitos y conductas aprendidas, institucionalización, reacciones ante el estrés agudo.) La prevalencia de abuso y dependencia de sustancias en población con DI va desde el 0,5% al 2,6%. Lo cual es menor que la población general. Pacientes con DI y dependencia a drogas se asocia a otras enfermedades psiquiátricas (42-54%). Se ha informado que las personas con discapacidad intelectual en América Latina a menudo están institucionalizadas y escondidas de la sociedad en instalaciones deficientes y superpobladas.


Clinical Case: Female, 23 years old. Intellectual disability. He attends a special school (she does not read or write). Institutionalized. Reason for admission: Patient enters in October 2017 brought by police officers to be found in the street under the effect of multiple substances, with suicidal ideation. Days before she was expelled from the home because of assaulting caregivers. Admission diagnoses: Moderate intellectual disability. Suicidal syndrome, Disorder due to drug dependence. Hebephrenic schizophrenia? Evolution: Maintains fluctuating severe behavioral imbalances, with serious difficulties in managing rage, which leads to hetero and self-aggressive behaviors. Treatment plan: pharmacological (clozapine), Psychological (CBT), Social (adequate post-hospitalization discharge device). Clozapine for psychotic disorders in adults with intellectual disabilities. The main risk of attributing some of these behaviors to a supposed "psychosis" is that of "medicalizing" and dealing inappropriately. It is important to rule out environmental and learning factors (habits and behaviors learned, institutionalization, reactions to acute stress. The prevalence of substance abuse and dependence in the population with ID ranges from 0.5% to 2.6%. Which is less than the general population. Patients with ID and drug dependence are associated with other psychiatric illnesses (42-54%). It is reported that people with intellectual disabilty in Latin America are often institutionalized and hidden from society in poor and overcrowded facilities.


Subject(s)
Humans , Female , Young Adult , Substance-Related Disorders/diagnosis , Intellectual Disability/diagnosis , Intellectual Disability/therapy , Psychotherapy , Psychotic Disorders , Antipsychotic Agents/therapeutic use , Clozapine/therapeutic use , Substance-Related Disorders/complications , Substance-Related Disorders/therapy , Suicidal Ideation , Intellectual Disability/classification , Intellectual Disability/complications , Intellectual Disability/etiology
19.
West Indian med. j ; 67(4): 323-327, Oct.-Dec. 2018. tab
Article in English | LILACS | ID: biblio-1045863

ABSTRACT

ABSTRACT Objective: To explore the relationship between substance use and depressive symptomatology among adolescents in Colombia. Methods: Adolescents aged 13-19 years from a rural city in Colombia completed the Spanish version of the Alcohol, Smoking and Substance Involvement Screening Test and the Kutcher Adolescent Depression Scale-6 (KADS-6). Results: Regression analyses indicated that gender, having used cannabis, having used sedatives, and having a family member who used illegal drugs were predictive of higher symptom levels of depression according to KADS-6. Conclusion: The results of this study suggested that substance use was associated with depressive symptoms in this sample of Colombian adolescents.


RESUMEN Objetivo: Explorar la relación entre el uso de sustancias y la sintomatologia depresiva entre adolescentes en Colombia. Métodos: Los adolescentes de 13 a 19 años de una ciudad rural en Colombia completaron la versión en español de la Prueba de Detección de Alcohol, Tabaco y Sustancias (ASSIST, en inglés) y la Escala de Depresión pasa Adolescentes de Kutcher-6 (KADS-6, en inglés). Resultados: Los análisis de regresión indicaron que tanto el género, como el haber consumido cannabis, usado sedantes, y tener un miembro de la familia que usó drogas ilegales, fueron predictores de niveles más altos de sintomas depresivos de acuerdo con la escala KADS-6. Conclusión: Los resultados de este estudio sugirieron que el uso de sustancias estaba asociado con sintomas depresivos en esta muestra de adolescentes colombianos.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Adolescent Behavior , Substance-Related Disorders/complications , Depression/etiology , Underage Drinking/statistics & numerical data , Surveys and Questionnaires , Colombia
20.
Rev. bras. ginecol. obstet ; 40(9): 518-526, Sept. 2018. tab, graf
Article in English | LILACS | ID: biblio-977824

ABSTRACT

Abstract Objective To assess the relationship between the use of psychoactive substances during pregnancy and the occurrence of severe maternal morbidity (SMM), perinatal outcomes and repercussions on the neuropsychomotor development of exposed children. Methods A case-control study nested within a cohort of severe maternal morbidity (COMMAG) was performed. Women with SMM were considered cases. Controls were thosewith low-risk pregnancy,without SMMand admitted during the same time period as the cases. Cohort data were collected retrospectively in hospital records for childbirth. A face-to-face interview was also performed with 638 women (323 without SMM and 315 with SMM) and their children of the index pregnancy between 6 months and 5 years after childbirth. During the interview, substance abuse during pregnancy was assessed by a modified question from the Alcohol, Smoking and Substance Involvement Screening Test 2.0 (ASSIST) and the neuropsychomotor development in the children was assessed by the Denver Developmental Screening Test, 2nd edition. Results The prevalence of licit or illicit drug use during pregnancy was ~ 17%. Among drug users, 63.9% used alcohol, 58.3% used tobacco, 9.2% used cocaine/crack and 4.6% used marijuana. There was no association between drug use during pregnancy and SMM, although tobacco use during pregnancy was associated with bleeding, presence of near-miss clinical criteria (NMCC) and alteration in infant development; alcohol use was associated with neonatal asphyxia; and cocaine/crack use was associated with the occurrence of some clinical complications during pregnancy. Conclusion The use of psychoactive substances during pregnancy is frequent and associated with worse maternal, perinatal and child development outcomes.


Resumo Objetivo Avaliar a relação entre o uso de substâncias psicoativas na gestação e a ocorrência de morbidade materna grave (MMG), resultados perinatais e repercussões no desenvolvimento neuropsicomotor das crianças expostas. Métodos Estudo de caso-controle a partir de uma coorte de morbidade materna grave (COMMAG). Mulheres com MMG foram consideradas casos. Controles foram mulheres com gestação de baixo risco, admitidas no mesmo período que os casos. Os dados da coorte foram coletados retrospectivamente em prontuários de internação para o parto e entrevistas presenciais conduzidas com 638 mulheres e seus filhos da gestação-índice, entre 6 meses e 5 anos após o parto. Na entrevista, o uso de substâncias na gestação foi avaliado com uma pergunta modificada introduzida no questionário para triagem do uso de álcool, tabaco e outras substâncias 2.0 (ASSIST, na sigla em inglês) e o desenvolvimento neuropsicomotor das crianças foi avaliado pelo teste de triagem do desenvolvimento Denver II. Resultados A prevalência do uso de drogas lícitas ou ilícitas na gestação foi de cerca de 17%. Das usuárias, 63,9% usaram álcool, 58,3% usaram tabaco, 9,2% usaram cocaína/crack e 4,6% usaram maconha. Não houve associação entre o uso de drogas na gestação eMMG. Contudo, o uso de tabaco foi associado a hemorragia, presença de critérios clínicos de near miss e alteração no desenvolvimento infantil. O uso de álcool foi associado à asfixia neonatal e o uso de cocaína/crack à ocorrência de alguma complicação clínica na gestação. Conclusão O abuso de substâncias lícitas ou ilícitas na gestação é frequente e associado a piores desfechos maternos, perinatais e do desenvolvimento infantil.


Subject(s)
Humans , Female , Pregnancy , Infant , Child, Preschool , Pregnancy Complications/chemically induced , Psychotropic Drugs/adverse effects , Neurodevelopmental Disorders/chemically induced , Severity of Illness Index , Pregnancy Outcome , Case-Control Studies , Retrospective Studies , Substance-Related Disorders/complications
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