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1.
Odontol. Clín.-Cient ; 20(1): 68-73, jan.-mar. 2021. ilus, tab
Article in Portuguese | LILACS, BBO | ID: biblio-1367957

ABSTRACT

A queilite actínica (QA) é uma desordem potencialmente maligna que se desenvolve principalmente no lábio inferior, decorrente da exposição crônica a luz solar. O objetivo desse estudo é elucidar, a partir de uma revisão da literatura, as abordagens não cirúrgicas mais atuais para o tratamento da QA. Foi realizada uma busca nas bases de dados PubMed, Scielo e Cochrane, sendo obtidos 280 artigos e após aplicação dos critérios de elegibilidade, foram utilizados no presente traba lho 16 estudos. Várias abordagens, como, diclofenaco sódico, mebutato de ingenol, imiquimode, 5-fluorouracil, fludroxicortida e terapia fotodinâmica, são apontadas e estudadas como forma de tratamento para a QA. Entretanto, faltam trabalhos para que se estabeleça um consenso sobre a terapêutica não-cirúrgica mais adequada... (AU)


Actinic cheilitis (AC) is a potentially malignant disorder that develops mainly on the lower lip, result ing from a chronic exposure to sunlight. The objective of this study is to elucidate, from a literature review, the most current non-surgical approaches for the treatment of AC. A search was performed in the PubMed, Scielo and Cochrane databases, obtaining 280 papers and after applying the eligibility cri teria, 16 studies were used in the present study. Various approaches, such as diclofenac sodium, ingenol mebutate, imiquimod, 5-fluorouracil, fludroxycortide and photodynamic therapy are pointed out and studied as a form of treatment for AC. However, there is a lack of work to establish a consensus on the most appropriate non-surgical therapy... (AU)


Subject(s)
Photochemotherapy , Cheilitis/drug therapy , Conservative Treatment , Lip Diseases , Sunlight , Lip
2.
Gac. méd. Méx ; 157(2): 127-132, mar.-abr. 2021. tab
Article in Spanish | LILACS | ID: biblio-1279091

ABSTRACT

Resumen Objetivo: Conocer la prevalencia de las conductas exposición y protección solar en un grupo de adolescentes y compararlos con un grupo de adultos en la Ciudad de México. Material y métodos: Estudio transversal descriptivo en estudiantes de 16 a 18 años y en adultos mayores de 18 años. Resultados: Se encuestaron 748 alumnos, 60 % mujeres y 40 % hombres. El 90 % busca la sombra, el 70.1 % evita exponerse al sol de las 10 a las 16 horas y el 30.6 % usa filtro solar. De 620 adultos, 67.5 % mujeres y 32.4 % hombres, el 82.6 % buscan la sombra, el 60.2 % evita el sol de las 10 a las 16 horas y el 48.1 % utiliza filtro solar. El 72.9 % de adultos y el 80.8 % de adolescentes se exponen al sol debido a actividades domésticas. Discusión: Existe una tendencia similar en las conductas de protección y exposición solar en adolescentes y adultos. Es alta la prevalencia de uso de fotoprotector en adultos en comparación con los adolescentes.


Abstract Objective: To know the prevalence of sun exposure and protection behaviors in a group of adolescents and to compare them with a group of adults in Mexico City. Material and methods: Descriptive, cross-sectional study in students aged 16 to 18 years and in adults older than 18 years. Results: Seven-hundred and forty-eight students were surveyed; 60 % were females and 40 % males; 90 % seek shade, 70.1 % avoid exposing themselves to the sun from 10.00 to 16.00 hours and 30.6 % use sunscreen. Out of 620 adults, 67.5 % were women and 32.4 % were men; 82.6 % seek shade, 60.2 % avoid the sun from 10.00 to 16.00 hours and 48.1% use sunscreen; 72.9 % of adults and 80.8 % of adolescents are exposed to the sun due to domestic activities. Discussion: There is a similar trend in sun protection and exposure behaviors in adolescents and adults. The prevalence of sunscreen use in adults is high in comparison with adolescents.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Young Adult , Radiation Protection/methods , Sunlight/adverse effects , Sunscreening Agents/administration & dosage , Health Behavior , Students/statistics & numerical data , Time Factors , Cross-Sectional Studies , Health Surveys , Age Factors , Mexico
3.
Arch. latinoam. nutr ; 71(1): 5-12, mar. 2021. tab, graf
Article in Spanish | LILACS, LIVECS | ID: biblio-1283237

ABSTRACT

La vitamina D es esencial para el funcionamiento del organismo. Su deficiencia puede estar asociada tanto a patologías óseas, como a otras afecciones sistémicas. La prevalencia de la hipovitaminosis está aumentando, en todas las edades, incluidos niños y adolescentes. El objetivo del presente estudio fue evaluar los niveles sanguíneos de vitamina D en niñas colombianas, analizando también la dieta, la actividad física y la exposición solar. Se realizó un estudio descriptivo transversal con 52 niñas sanas prepúberes de Pasto (Colombia), entre 7 y 10 años. Se analizaron los niveles de albúmina, calcio, fósforo, magnesio, calcitriol (1,25 dihidroxicolecalciferol) y calcidiol (25 hidroxicolecalciferol). Se realizaron encuestas sobre hábitos alimentarios, actividad física y exposición solar. El 51,1% de las niñas evaluadas presentó insuficiencia de 25-OH-VITD y el 40% presentó deficiencia (< 20 ng/mL). Ninguna niña se encontraba en desnutrición u obesidad, el 10% se encontraba en riesgo de bajo peso (IMC ≤ -1DE y > -2DE), el 4 % presentaba sobrepeso (≥ +1DE y < +2DE), y el 34 % se encontraban en riesgo de talla baja (T/E: -1 y -2 DE). La ingesta media de calorías/día fue inferior a las recomendadas. Se observó una ingesta deficiente de vitamina D, calcio y magnesio (p > 0,05), así como de fibra (p > 0,05). Se pone de manifiesto una deficiencia de vitamina D en las niñas evaluadas a pesar de tener una actividad física y una exposición solar adecuadas. Además, se observan ingestas deficientes de fibra, calcio, magnesio y vitamina D. Habría por tanto que asegurar la ingesta e incluso suplementar para evitar problemas de salud en la edad adulta(AU)


Vitamin D is essential for the body to function. Its deficiency can be associated with bone pathologies as well as other systemic conditions. The prevalence of hypovitaminosisis increasing, in all ages, including children and adolescents. The objective of this study was to evaluate blood levels of vitamin D in Colombian girls, also analyzing diet, physical activity and sun exposure. A descriptive cross-sectional study was carried out with 52 healthy prepubertal girls from Pasto (Colombia), between 7 and 10 yearsold. The levels of albumin, calcium, phosphorus, magnesium, calcitriol (1.25 dihydroxycholecalciferol) and calcidiol (25 hydroxycholecalciferol) were analyzed. Surveys were conducted one a ting habits, physicalactivity and sun exposure. 51.1% of the girls evaluated presented 25-OH-VITD insufficiency and 40% presented deficiency (<20 ng / mL). None of the girls were under nourished or obese, 10% were at risk of low weight (BMI ≤ -1SD and> -2SD), 4% were overweight (≥ + 1DE and <+ 2DE), and 34% were they were at risk of short stature (T / E: -1 and -2 SD). The average calorie intake / day was lower than recommended. A deficient intake of vitamin D, calcium and magnesium (p> 0.05), as well as fiber (p> 0.05) was observed. A vitamin D deficiency is evident in the girls evaluated despite adequate physical activity and sun exposure. In addition, deficient intakes of fiber, calcium, magnesium and vitamin D are observed. Therefore, it would be necessary to ensure the intake and even supplement to avoid health problems in adulthood(AU)


Subject(s)
Humans , Female , Child , Sunlight , Vitamin D Deficiency/blood , Exercise , Diet , Vitamin D Deficiency/epidemiology , Cross-Sectional Studies , Colombia/epidemiology , Eating
4.
Braz. j. biol ; 80(4): 891-896, Oct.-Dec. 2020. tab, graf
Article in English | LILACS | ID: biblio-1142545

ABSTRACT

Abstract Baculoviruses are considered as effective bio pesticides except of being not active under sunlight conditions. The aim of this study is to evaluate the capability of moringa extract to prolong virus activity under Egyptian field conditions especially that Moringa proved to be strong protective material under previous investigation under laboratory conditions the addition of moringa filters were tested on tomato plant foliage. Results are based on leaf bioassay using Spodoptera littoralis test insect and its nuclepolyhedrovirus (SpliNPV) as standard materials. The Original Activity Remaining (OAR) and Lethal Infectivity Time to 50% (LIT50) were estimated after exposure to natural sunlight. cacao and green tea were tested as comparative materials, which proved to be effective as virus protective agent in earlier investigations. The results showed that moringa additive at 10% sustained 50% of virus activity for 193.53 hours and 62.05 and 23.023 hours post application for cacao and green tea; respectively. While virus alone treatment lasts for only 17.551 hours. Moringa generally available, relatively cheap; it also has been tested and proved to be non-toxic, safe, and friendly to the environment. The obtained results showed the activity of moringa water extract in prolonging the virus activity under field application.


Resumo Os baculovírus são considerados como biopesticidas eficazes, exceto por não estarem ativos sob condições de luz solar. O objetivo deste estudo é avaliar a capacidade do extrato de moringa para prolongar a atividade do vírus sob condições de campo egípcias, tendo em vista que Moringa provou ser um material protetor forte sob investigação anterior em condições de laboratório a adição de filtros moringa foram testados na folhagem de plantas de tomate. Os resultados são com base em bioensaios foliares utilizando o inseto-teste Spodoptera littoralis e seu vírus de poliedrose nuclear (VPNSl) como materiais padrões. A Atividade Original Restante (AOR) e o Tempo de Infectividade Letal até 50% (LIT50) foram estimados após a exposição à luz solar natural. Cacau e chá verde foram testados como materiais comparativos, que se mostraram eficazes como agentes protetores do vírus em investigações anteriores. Os resultados mostraram que a moringa aditiva a 10% sustentou 50% da atividade viral por 193,53 horas e 62,05 e 23,023 horas após a aplicação de cacau e chá verde, respectivamente. Enquanto o tratamento sozinho do vírus dura apenas 17,551 horas, a moringa geralmente está disponível, e é relativamente barata; e a mesma também foi testada e provou ser não tóxica, segura e propícia ao meio ambiente. Os resultados obtidos mostraram a atividade do extrato aquosa da moringa no prolongamento da atividade do vírus sob aplicação em campo.


Subject(s)
Animals , Moringa , Sunlight , Water , Plant Extracts/pharmacology , Baculoviridae , Plant Leaves , Egypt
5.
Rev. méd. Minas Gerais ; 30(supl.2): 18-21, 2020.
Article in Portuguese | LILACS | ID: biblio-1151004

ABSTRACT

Introdução: A maculopatia ou retinopatia solar é uma lesão foto-traumática da mácula causada pela observação direta ou indireta de fontes luminosas intensas, que ocorre comumente na presença de distúrbios psíquicos ou após o uso de drogas recreativas. O prognóstico visual varia e a conduta é expectante. Descrição do caso: Paciente V.V.A.M., sexo masculino, 20 anos, estudante, com queixa de escotoma central em ambos os olhos. Nega antecedentes patológicos e oculares. Solicitaram-se tomografia de coerência óptica (OCT) e retinografia, que revelaram uma lesão central, bilateral e simétrica na retina externa. Paciente relatou ter feito uso de Dietilamida de ácido lisérgico (LSD) e, sob influência da droga, ter olhado de forma direta para o sol por aproximadamente 40 minutos. Discussão: O prognóstico da retinopatia solar é variável e relaciona-se com o tempo de exposição e com o comprimento da onda da fonte de luz. A etiopatogênese é explicada pelo dano causado ao epitélio pigmentar da retina (EPR) pela radiação. Conclusões: Deve haver maior orientação ao público sobre os possíveis efeitos danosos de exposição a fontes de luz de origens diversas. Além disso, destaca-se a importância do OCT para a identificação da maculopatia solar. (AU)


Introduction: Solar maculopathy or retinopathy is photo-traumatic damage created on the macula, caused by direct or indirect observation of intense light sources, commonly occurring in the presence of psychic disorders or after the use of recreational drugs. The visual prognosis varies. There is currently no known treatment. Case report: A 20-year-old male with no previous complaints reported central scotoma in both eyes despite 20/20 uncorrected vision. Bilateral, symmetric, central changes could be seen in the macula in fundoscopy. Optical coherence tomography (OCT) confirmed loss of the external retina suggestive of Solar Maculopathy. The patient later claimed to have spent 40 minutes looking directly into the sun after use of Lysergic Acid Diethylamide (LSD). Discussion: The prognosis of solar retinopathy is related to the exposure time and to the wavelength of the light source, with those between 300-350 nm being the most harmful. Its etiopathogenesis is explained by damage caused to the retinal pigment epithelium (EPR) caused by radiation, interrupting the interdigitations between this layer and the external segment of the photoreceptors. Ophthalmoscopically, solar maculopathy is characterized by a small foveolar lesion that might become yellowish in the days following exposure, in the form of exudate or edema, followed by loss of foveal reflex and thinning of the fovea. The initial yellowed lesions are subsequently replaced by a spotted EPR or even by a lamellar orifice. Conclusions: There should be public guidance on the possible harmful effects of exposure to sources of light from diverse origins, as it usually occurs during solar eclipses, after exposure to certain types of lasers or observation of fires since this habit can cause severe and sometimes irreversible visual loss. (AU)


Subject(s)
Humans , Male , Adult , Young Adult , Macular Degeneration , Scotoma , Sunlight/adverse effects , Lysergic Acid Diethylamide , Macular Degeneration/etiology
6.
Article in Korean | WPRIM | ID: wpr-811316

ABSTRACT

PURPOSE: We determined whether elevated serum alkaline phosphatase (ALP) was related to prevalence, location, type, length, and recurrence of pterygium in a population from the Republic of Korea.METHODS: A nationwide cross-sectional dataset, the Korean National Health and Nutrition Examination Survey (2008–2011), was used in this study. All participants were > 30 years of age and underwent the ALP test and ophthalmic evaluation (n = 22,359). One-way analysis of variance, the chi-square test, and Fisher's exact test were used to compare characteristics and outcomes among participants. Multivariable logistic regression was used to examine the possible associations between serum ALP levels and various types of pterygium. Data were adjusted for known risk factors for development of pterygium and ALP elevation (age, sex, residence, sunlight exposure, drinking, smoking, hypertension, diabetes, BMI, AST, ALT, vitamin D, and HDL).RESULTS: The overall prevalence of pterygium was 8.1%, and participants with pterygium had higher levels of serum ALP (p < 0.001). Participants with higher serum ALP had a significantly higher prevalence of all types of pterygium than those in the lower serum ALP quartiles. After adjusting for potential confounding factors, multivariate logistic regression analysis revealed that ALP was associated with the prevalence of pterygium (odds ratio [OR], 1.001; p = 0.038). Trend analysis between the OR and ALP quartiles revealed a linear trend in overall prevalence and in the intermediate type of pterygium. Subgroup analysis revealed a stronger correlation in participants > 50 years of age. One-way analysis of variance revealed an association between the size of pterygium and serum ALP quartile levels. Serum ALP was not associated with recurrence of pterygium.CONCLUSIONS: Increased serum ALP was associated with the prevalence and size of pterygium.


Subject(s)
Alkaline Phosphatase , Cross-Sectional Studies , Dataset , Drinking , Hypertension , Korea , Logistic Models , Nutrition Surveys , Prevalence , Pterygium , Recurrence , Republic of Korea , Risk Factors , Smoke , Smoking , Sunlight , Vitamin D
7.
Article in English | WPRIM | ID: wpr-810963

ABSTRACT

BACKGROUND: Lack of sunlight exposure is the primary reason for the worldwide epidemic of vitamin D deficiency. Although recommended sunlight exposure guidelines exist, there is no evidence regarding whether current guidelines are optimal for increasing vitamin D levels among individuals with vitamin D deficiency.METHODS: Sixty Korean adults aged 20–49 years with serum 25-hydroxyvitamin D (25[OH]D) levels of < 20 ng/mL were randomly assigned to three groups: sunlight exposure (n = 20), vitamin D supplementation groups (n = 20), and daily living (n = 20) for 1 month. The sunlight exposure group had sunlight exposure on 20% to 30% of their body surface areas for 30–60 minutes per day, 3 times a week during the summer season. Vitamin D supplementation was prescribed with 800 IU/day of vitamin D. The serum levels of 25(OH)D were measured at baseline and at 1-month follow-up examinations.RESULTS: The largest change in serum 25(OH)D was observed among the vitamin D supplementation group (+3.5 ng/mL, P < 0.001). The sunlight exposure group showed a slight increase in serum 25(OH)D level, but the absolute increase was less than one-third that of the vitamin D supplementation group (+0.9 ng/mL, P = 0.043). Only two participants in the sunlight exposure reached serum concentrations of 25(OH)D ≥ 20 ng/mL at follow-up. The daily living group showed no difference in vitamin D levels (−0.7 ng/mL, P = 0.516).CONCLUSION: Sunlight exposure was not sufficient to overcome vitamin D insufficiency or deficiency in the current study subjects. Effectiveness of current sunlight exposure guidelines among various populations should be reassessed in larger clinical studies.TRIAL REGISTRATION: Clinical Research Information Service Identifier: KCT0002671


Subject(s)
Adult , Body Surface Area , Follow-Up Studies , Humans , Information Services , Seasons , Solar System , Sunlight , Vitamin D Deficiency , Vitamin D , Vitamins
8.
Arq. bras. med. vet. zootec. (Online) ; 71(6): 2057-2064, Nov.-Dec. 2019. tab, graf
Article in Portuguese | LILACS, VETINDEX | ID: biblio-1055114

ABSTRACT

Objetivou-se avaliar o perfilhamento da Brachiaria brizantha cv. Piatã, como base para identificação das frequências e alturas pós-corte mais adequadas para essa gramínea forrageira. Em um esquema fatorial 2 x 2, foram estudadas combinações entre duas frequências de corte (95% e máxima interceptação de luz, ILmax) e duas alturas pós-corte (15 e 20cm). O delineamento foi em blocos ao acaso, com três repetições, totalizando 12 unidades experimentais de 14m2 cada. Foram avaliadas as taxas de aparecimento (TApP) e de mortalidade (TMoP) de perfilhos, o índice de estabilidade (IE) e a densidade populacional de perfilhos. A maior TApP no dossel sob IL de 95% ocorreu no Verão 1, em comparação às demais épocas. Nos dosséis manejados com ILmax, a TApP foi superior no Verão 1 e no Outono, quando comparados às outras épocas. No Verão 1 e no Final da Primavera e Verão 2, houve as maiores TMoP para as duas frequências de corte avaliadas. No Outono, a TMoP também foi alta no dossel cortado com ILmáx. O IE foi menor durante o Verão 1 no dossel sob ILmax e com 15cm de resíduo (0,995). Porém, nas demais épocas, os valores de índice de estabilidade foram maiores que uma unidade e não foram influenciados pela frequência e altura pós-corte. A densidade populacional de perfilhos foi menor no Verão 1, em comparação às demais épocas. O capim-piatã pode ser desfolhado com qualquer combinação entre as interceptações de luz, 95% e ILmax, e alturas pós-corte, 15 ou 20cm, sem prejudicar a persistência do pasto.(AU)


The aim of this study was to evaluate the tillering of Brachiaria brizantha cv. Piatã, as a basis for identifying the frequencies and post-cutting heights most suitable for this grass. In a 2 x 2 factorial scheme, combinations between two cut frequencies (95% and maximum light interception, IL max ) and two post-cut heights (15 and 20cm) were studied. The experimental design was in randomized blocks with 3 replicates, totaling 12 experimental units of 14m 2 each. Rates of appearance (TAR) and mortality (TMR) of tillers, the stability index and the population density of tillers were evaluated. The highest TAR in the canopy under 95% IL occurred in Summer 1, in comparison to the other seasons. In the canopies managed with IL max , TAR was higher in summer 1 and in autumn, when compared to other seasons. In summer 1 and at the end of spring and summer 2, there were the highest TMR for the two cutoff frequencies evaluated. In autumn, TMR was also high in the canopy cut with IL max . IE was lower during summer 1 in the canopy under IL max and 15cm of residue (0.995). However, at other times, stability index values were greater than one unit and were not influenced by post-cut frequency and height. The population density of tillers was lower in Summer 1, when compared to the other seasons. The piata grass may be defoliated with any combination of light intercepts, 95% and ILmax, and post-cut heights, 15 or 20cm, without impairing the persistence of pasture.(AU)


Subject(s)
Sunlight , Plant Physiological Phenomena , Brachiaria/growth & development
9.
Mem. Inst. Invest. Cienc. Salud (Impr.) ; 17(2): 36-43, ago. 2019. tab, ilus
Article in Spanish | LILACS, BDNPAR | ID: biblio-1008411

ABSTRACT

La vitamina D es una hormona cumple una función en la regulación de numerosos genes que participan en la proliferación y maduración celular. El objetivo de este trabajo fue determinar la prevalencia de valores inadecuados de esta vitamina en jóvenes sanos de Asunción e identificar los posibles factores de riesgo asociados. Estudio observacional descriptivo basado en datos clínico-epidemiológicos y en la determinación de la 25-hidroxivitamina D (25-OH vitamina D) por el método de quimioluminiscencia (CMIA). Se consideró valor adecuado ≥30 ng/dl, inadecuado por debajo de este rango y deficiente ≤20 ng/dl. El análisis estadístico se realizó con el programa R-proyect. Para establecer factores de riesgo para tener deficiencia de vitamina D se utilizó regresión logística bi y multivariante. Se incluyeron 817 jóvenes universitarios de edad promedio 21 años. La concentración de vitamina D tuvo una media de 25 ± 8 ng/dl, oscilando entre 64,3 y 2,4 ng/dl. El 75,5% de los participantes tenían valores inadecuados de vitamina D. La deficiencia de vitamina D fue significativamente (p = 0,006) más frecuente en mujeres, personas con sobrepeso (p = 0,03), con falta de exposición al sol (p = 0,001) y con sedentarismo (p = 0,0001). Este estudio confirma la elevada prevalencia de valores inadecuados de vitamina D en nuestro país y permite definir un perfil de muy alto riesgo para las jóvenes sedentarias y con sobrepeso, lo que justifica una atención especial de parte de los médicos y las instituciones responsables de la salud pública en nuestro país(AU)


Vitamin D is a hormone that plays a role in the regulation of numerous genes involved in cell proliferation and maturation. The objective of this work was to determine the prevalence of inadequate values of this vitamin in healthy young people of the city of Asunción and to identify the possible risk factors associated with it. Descriptive observational study based on clinical-epidemiological data and in the determination of 25-hydroxyvitamin D (25-OH vitamin D) by the chemiluminescence method (CMIA). It was considered appropriate values ≥30 ng/dl, inappropriate below this range and deficient <20 ng/dl. Statistical analyzes were carried out with the R-project program. To establish the association, bivariate and multivariate logistic regression was used. We included 817 university students with an average age of 21 years. The average value of the vitamin D concentration was 25 ± 8 ng/dl, ranging from 64.3 to 2.4 ng/dl. Inadequate vitamin D values were found in 75.5% of the participants. Vitamin D deficiency was significantly (p <0.006) more frequent in women, overweight people (p <0.03), lack of sun exposure (p = 0.001) and sedentary lifestyle (p = 0.0001). This study confirms the high prevalence of inadequate vitamin D values in our country and allows us to define a very high risk profile for sedentary and overweight young women, which justifies special attention from physicians and institutions responsible for public health in our country(AU)


Subject(s)
Humans , Male , Female , Adolescent , Adult , Vitamin D/blood , Vitamin D Deficiency/epidemiology , Sunlight , Body Weights and Measures , Body Mass Index , Prevalence , Cross-Sectional Studies , Risk Factors , Eating
10.
An. bras. dermatol ; 94(3): 279-286, May-June 2019. tab, graf
Article in English | LILACS | ID: biblio-1011121

ABSTRACT

Abstract: Background: Exposure to UVR provides benefits related to vitamin D synthesis, but also causes harms, since UVB is considered a complete carcinogen. There is no definition of the level of sun exposure and the proportion of exposed body required for proper synthesis of vitamin D in the skin without causing it damage. Objectives: This study aims to analyze the sun exposure index, vitamin D levels and clinical changes in the skin caused by constant sun exposure in the fishermen population. Methods: It is a cross-sectional, observational and analytical study. The sample consisted of fishermen and was calculated in 174 individuals. The questionnaire was applied, the dermatological examination was carried out and the examinations of calcidiol, parathyroid hormone, calcium and phosphorus were requested. Data were expressed as percentages. The comparative analysis was done through the Chi-square test, and the correlations were established through the Pearson's linear coefficient. Results: We observed that there was vitamin D deficiency in a small part of the cases (11.46%), and the frequency of diagnosis of skin cancer was 2.7% of the cases surveyed. Study Limitations: The difficulty in categorizing the sun exposure index. Conclusion: The fact that fishermen expose themselves to the sun chronically and have been exposed to the sun for more than 15 years, between 21 and 28 hours a week, and without photoprotection, were indicative factors for protection against vitamin D deficiency. Chronic exposure to sun and high vitamin levels D may be indicative of protection of this population against skin cancer.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Skin Neoplasms/etiology , Skin Neoplasms/epidemiology , Sunlight , Ultraviolet Rays , Vitamin D/biosynthesis , Vitamin D Deficiency/rehabilitation , Vitamin D Deficiency/epidemiology , Vitamin D/blood , Brazil/epidemiology , Body Mass Index , Nutritional Status , Cross-Sectional Studies , Surveys and Questionnaires , Diet
11.
An. bras. dermatol ; 94(3): 331-333, May-June 2019. graf
Article in English | LILACS | ID: biblio-1011115

ABSTRACT

Abstract: Solar urticaria is a rare form of physical urticaria mediated by immunoglobulin E. The lesions appear immediately after the sun exposure, interfering with the patient's normal daily life. Omalizumab, a monoclonal anti-IgE antibody, has been recently approved for the treatment of chronic spontaneous urticaria, and the latest reports support its role also in the treatment of solar urticaria. Hereby, we report a case of solar urticaria refractory to conventional treatment strategies, with an excellent response to treatment with omalizumab and phototesting normalization.


Subject(s)
Humans , Male , Middle Aged , Sunlight/adverse effects , Urticaria/drug therapy , Anti-Allergic Agents/therapeutic use , Omalizumab/therapeutic use , Photosensitivity Disorders/diagnosis , Photosensitivity Disorders/etiology , Photosensitivity Disorders/drug therapy , Urticaria/diagnosis , Urticaria/etiology
12.
An. bras. dermatol ; 94(2): 157-163, Mar.-Apr. 2019. tab, graf
Article in English | LILACS | ID: biblio-1001134

ABSTRACT

Abstract BACKGROUND: Skin cancer is common in Brazil and is related to sun exposure, among other risk factors. There are no data on the incidence of malignant skin neoplasm in rural workers in western Paraná. OBJECTIVE: To analyze the incidence and profile of rural workers who were diagnosed with skin cancer at a reference service in Cascavel, western Paraná, in the last five years (2011-2016). METHODS: This retrospective cross-sectional study was carried out through a review of the anatomopathological reports of rural workers diagnosed with skin cancer at Cascavel Oncology Center (CEONC), in Cascavel. The following variables were collected: year of diagnosis, age, gender, injury location and histological subtype. RESULTS: A total of 681 cases of malignant epithelial neoplasia were identified, with a higher frequency in the 61-70 age group. Data analysis showed an increase of about 210% in the occurrence of skin cancers in the last 5 years. The cephalic region was the most affected, and the most common histological subtype was nodular basal cell carcinoma. There was no association between gender and location. STUDY LIMITATIONS: This is a retrospective study and analysis of a secondary data bank. CONCLUSION: This study is a regional estimation of the incidence of cutaneous neoplasms and provides evidence of a considerable increase in the number of diagnoses in rural workers from western Paraná, Brazil. Moreover, it is possible to conclude that the sample group studied is at risk of developing skin cancer.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Skin Neoplasms/epidemiology , Carcinoma, Basal Cell/epidemiology , Carcinoma, Squamous Cell/epidemiology , Melanoma/epidemiology , Rural Population/statistics & numerical data , Skin Neoplasms/etiology , Sunlight/adverse effects , Brazil/ethnology , Brazil/epidemiology , Carcinoma, Basal Cell/etiology , Carcinoma, Squamous Cell/etiology , Incidence , Cross-Sectional Studies , Retrospective Studies , Age Distribution , Face , Melanoma/etiology
13.
An. bras. dermatol ; 94(2): 172-181, Mar.-Apr. 2019. tab, graf
Article in English | LILACS | ID: biblio-1001149

ABSTRACT

Abstract BACKGROUND: Excessive sun exposure is the major risk factor for skin cancer. Thus, sun exposure behavior is the major focus for prevention of this disease, since it is potentially modifiable. Increasing the knowledge on sun related habits and other skin cancer risk factors is fundamental in the development of preventive programs, especially when directed to young people. OBJECTIVES: To assess the photoprotection habits and the knowledge about skin cancer in college students. METHODS: We conducted a cross-sectional study from Oct. 16 to Feb. 17, including 371 students from the Federal University of Santa Maria, RS, Brazil, through a self-administered questionnaire. RESULTS: The level of knowledge about skin cancer and photoprotection was unsatisfactory in more than 10% of the students. The occurrence of sunburn was extremely high among students, and 25% reported at least one episode of second degree sunburn. Proper use of sunscreen was referred by only 34% of individuals. Students who reported having received photo education in college were associated with a more consistent use of sunscreen. STUDY LIMITATIONS: health area represented a large part of the sample; instrument validated outside Brazil. CONCLUSIONS: Young people are unaware of basic information about sun protection and exposure. Even among those with proper knowledge, the use of photoprotective measures is very low. The sun exposure has shown to be excessive in most of the students, which makes this population an important target for photo-educational measures.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Young Adult , Students/psychology , Sunlight , Health Knowledge, Attitudes, Practice , Environmental Exposure/statistics & numerical data , Habits , Skin Neoplasms/prevention & control , Sunburn/prevention & control , Sunscreening Agents/therapeutic use , Brazil , Skin Pigmentation , Cross-Sectional Studies , Surveys and Questionnaires/statistics & numerical data
14.
An. bras. dermatol ; 94(1): 56-61, Jan.-Feb. 2019. tab, graf
Article in English | LILACS | ID: biblio-983734

ABSTRACT

Abstract: Background: Most of the organism's vitamin D (VD) is obtained through the cutaneous synthesis after exposure to the sun's UVB radiation. Sunscreens are indicated for the prevention of actinic damage to the skin, however, there are few clinical trials assessing the synthesis of cutaneous VD in real-life situations of sun exposure with ordinary clothing and usual photoprotection. Objectives: To evaluate the synthesis of VD with suberythemal sun exposure in healthy adults using topical photoprotection (SPF 30). Methods: Quasi-experimental study, conducted at Rio de Janeiro (Brazil), during winter, with 95 healthy adults who had 25-OH-VD checked twice, 24 hours apart, and were exposed to the sun (UVB=20 mJ/cm2), according to a randomized grouping: SC - use of SPF 30 on the face, neck and chest (n=64), NO - no sunscreens (n=10), CO - confined from sun exposure for 24h (n=21). The groups were matched according to the propensity score related to gender, age, phototype, body mass index, glycosylated hemoglobin and baseline levels of VD. The outcome evaluated was the variation (ΔVD) in serum level of 25-OH-VD (ng/ml) between the groups. Results: A statistically significant difference was identified between CO and SC groups [median (p25-p75)]: ΔVD =1.4 (-0.3-3.6) vs. 5.5 (4.8-6.6); p<0.01. There was no difference between SC and NO groups: 5.4 (3.1-6.1) vs. 4.1 (2.5-6.0); p=0.17. Study limitations: Laboratory analysis technique (chemiluminescence) with great variability, loss of food intake standardatization, unbalanced groups. Conclusions: Suberythemal sun exposure with sunscreen (SPF 30) provides similar vitamin D serum variation than without photoprotection in healthy adults.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Sunlight , Sunscreening Agents , Vitamin D/blood , Reference Values , Skin/radiation effects , Time Factors , Vitamin D Deficiency , Statistics, Nonparametric , Luminescent Measurements
15.
Korean Journal of Medicine ; : 353-357, 2019.
Article in Korean | WPRIM | ID: wpr-759948

ABSTRACT

Urticaria is a common cutaneous disease characterized by recurrent and transient wheals and pruritus, sometimes accompanied angioedema. The classification of urticaria is based on the duration of the disease and whether extrinsic triggers are identified or not. Acute urticaria is usually occurred by specific causes, such as drug, food, and infection, etc. Therefore, acute urticaria can be remitted within 6 weeks just by avoiding the exposure to the causes. However, chronic urticaria defined as repeatedly occurred itchy wheals and/or angioedema for at least 6 weeks, has a significant effect on patients' quality of life. Chronic inducible urticaria can be triggered by various physical stimuli including dermographism, delayed pressure, cold, heat, cholinergic stimuli, sunlight, and exercise. Chronic spontaneous urticaria (CSU) is diagnosed when no specific extrinsic cause is identified in the patients. CSU due to autoimmune mechanism accounts for 30–50%, autologous serum skin test and anti-thyroid autoantibody can be evaluated. However, various physical stimuli, emotional or physical stress, drugs, particularly aspirin and non-steroidal anti-inflammatory drugs can exacerbate urticaria in 30–75% of patients with CSU. Allergic diseases and autoimmune diseases are more common in CSU patients than in general populations. To assess the severity of urticaria and to adjust treatment step, urticaria activity score over 7 days, calculated by the number of wheals and the severity of pruritus, is recommended by recent international guidelines.


Subject(s)
Angioedema , Aspirin , Autoimmune Diseases , Classification , Diagnosis , Hot Temperature , Humans , Pruritus , Quality of Life , Skin Tests , Sunlight , Urticaria
16.
Article in Korean | WPRIM | ID: wpr-759629

ABSTRACT

OBJECTIVES: Although the number of laboratory workers is constantly increasing every year, few studies have been conducted on the health and nutritional status of these research workers. This study determined the health status of laboratory workers by analyzing their anthropometric indices, dietary life, vitamin D status and blood clinical indices. METHODS: The subjects consisted of 100 female laboratory workers. This study investigated their diet, anthropometric indices, vitamin D status and blood clinical indices. The subjects were divided into two groups according to their duration of working in a laboratory (<1 year,≥1 year). RESULTS: The average age and body mass index (BMI) of subjects were 23.18 years and 21.51 kg/m2, respectively Those subjects with over 1 year employment (≥1 year) had a significantly higher waist-hip ratio than that of the subjects with the less than 1 year employment (<1 year). The mean serum vitamin D level of all the subjects was 10.04 ng/mL, which is close to a level of vitamin D deficiency. There was a significantly higher average intake of calories in the over 1 year employment group as compared to that of the less than 1 year employment group. The frequency of eating sweet snacks was significantly higher for the over 1 year employment group. The correlation analysis showed a significant positive correlation between the serum 25-(OH)-vitamin D level and the time of exposure to sunlight, while dietary intake of vitamin D did not show correlation with the serum 25-(OH)-vitamin D level. However, the serum 25-(OH)-vitamin D level was also negatively correlated with both the percentage of body fat and visceral fat. CONCLUSIONS: Laboratory workers are a very high risk group in terms of their nutritional status of vitamin D. Therefore, they need greater time of exposure to sunlight as well as increasing their dietary consumption of vitamin D. In addition, it is important for laboratory worker to practice regular and balanced dietary habits in order to maintain a healthy life.


Subject(s)
Adipose Tissue , Body Mass Index , Diet , Eating , Employment , Female , Feeding Behavior , Humans , Intra-Abdominal Fat , Nutritional Status , Snacks , Sunlight , Vitamin D Deficiency , Vitamin D , Vitamins , Waist-Hip Ratio
17.
Article in English | WPRIM | ID: wpr-762546

ABSTRACT

BACKGROUND: The risk factors for renal cancer include smoking, obesity, hypertension, and exposure to trichloroethylene. Recent studies have shown that low sunlight exposure increases the risk of developing a range of cancers, including renal cancer. Given that most of the daytime is spent at work, a lack of occupational sunlight exposure can be a risk factor for renal cancer. Therefore, this study examined the relationship between occupational sunlight exposure and the incidence of renal cancer. METHODS: This was a university hospital-based case-control study on renal cancer. Of the 706 newly diagnosed patients with renal cell carcinoma (RCC), 633 cases were selected; 73 who had no occupational history were excluded. In addition, 633 controls were selected from the general population after 1:1 matching with respect to sex, age (within 5 years), and residential area (constituency-level). Information on sunlight exposure by the occupational group was referred to data from France. To estimate the association between occupational sunlight exposure and the RCC risk, the odds ratios (ORs) were calculated using conditional logistic regression analysis. RESULTS: Sunlight exposure was divided into quartiles and the risk of RCC was analyzed. The adjusted OR of RCC (OR: 0.664, 95% confidence interval: 0.449–0.983) was significantly lower for the Q4 group than Q1 group but the Q2 and Q3 groups did not show significant results. The risk of RCC tended to decrease with increasing exposure to sunlight (p for trend < 0.028). CONCLUSIONS: Higher occupational sunlight exposure reduces the risk of RCC.


Subject(s)
Carcinoma, Renal Cell , Case-Control Studies , France , Humans , Hypertension , Incidence , Kidney Neoplasms , Logistic Models , Obesity , Occupational Groups , Odds Ratio , Risk Factors , Smoke , Smoking , Sunlight , Trichloroethylene
18.
Article in English | WPRIM | ID: wpr-764999

ABSTRACT

No abstract available.


Subject(s)
Internet , Sunlight
19.
Journal of Bone Metabolism ; : 193-199, 2019.
Article in English | WPRIM | ID: wpr-764251

ABSTRACT

BACKGROUND: Despite daily vitamin D recommendations, women with osteoporosis may not achieve optimal 25-hydroxy-vitamin D (25[OH]D) levels. We retrospectively evaluated the effect of education and vitamin D supplementation (1,000 IU/day) in Korean women with osteoporosis. METHODS: Sixty-one women with osteoporosis who were taking cholecalciferol (800–1,000 IU/day) were enrolled during 2011 to 2012. Forty patients (education only, Edu group) were educated on the importance of >30 min sunlight exposure daily while taking vitamin D. Twenty-one patients (education with vitamin D supplementation, Add group) were prescribed 1,000 IU/day cholecalciferol (total 1,800–2,000 IU/day) plus education. Patients were divided into 3 groups according to serum 25(OH)D status: deficiency (<20 ng/mL), insufficiency (20–30 ng/mL), and sufficiency (≥30 ng/mL). Furthermore, 25(OH)D levels were compared at baseline and after intervention for 3 months. RESULTS: The median (interquartile range) serum 25(OH)D concentration at baseline was 25.10 (18.95–33.60) ng/mL. The mean (±standard error) differences in 25(OH)D levels from baseline to post-intervention were 19.85±3.86 and 31.73±4.82 ng/mL in the Edu group and Add group, respectively. Eighteen patients (29.5%) had vitamin D deficiency, 25 (41.0%) had insufficiency, and 18 (29.5%) had sufficient levels. Optimal 25(OH)D (30 ng/mL or more) was achieved in 54.5% and 95.2% patients in the Edu group and Add group, respectively (P=0.003). CONCLUSIONS: We consider that vitamin D concentration should be measured on a regular basis in order to maintain an optimal level of vitamin D concentration, and education and supplementation is needed if not sufficient.


Subject(s)
Cholecalciferol , Education , Female , Humans , Osteoporosis , Postmenopause , Retrospective Studies , Sunlight , Vitamin D Deficiency , Vitamin D , Vitamins
20.
Article in Chinese | WPRIM | ID: wpr-774581

ABSTRACT

The study is aimed to investigate the effects of light intensities on growth,photosynthetic physiology,antioxidant systems and chemical composition of Viola yedoensis and provide cultivation references for V.yedoensis.Five groups of V.yedoensis were planted under five light intensities conditions,namely 100%,80%,50%,35%,5%of full sunlight,and then morphological index,growth,chlorophyll fluorescence parameters,photosynthetic parameters and antioxidant enzyme system indexes were measured during harvest.The results showed that there was no significant difference in the biomass of V.yedoensis among 35% -100%full sunlight,but the biomass of those were significantly higher than that in the 5%full sunlight treatment(P<0.05).The net photosynthetic rate,transpiration rate,stomatal conductance,intercellular CO_2 concentration and water use efficiency increased firstly and then decreased with the decrease of light intensity;F_m,F_v/F_mand Yield in 5% full sunlight treatment were significantly lower than those in the other four groups(P<0.05).The structure of chloroplast was normal under light intensity ranged from 50%to 100% full sunlight.The lamellar concentration of chloroplast matrix decreased and the starch granules decreased in 35% full sunlight treatment,and the margin of lamellar layer of chloroplast and substrate were blurred,and the starch granules were small and the number of starch granules decreased significantly under 5% full sunlight.MDA content in 5%full sunlight treatment was significantly higher than those in the other four groups(P<0.05).The total coumarin content and total flavonoid content decreased with the decrease of light intensity.In summary,the light in-tensity range suitable for the growth of V.yedoensis is wide(ranging from 35% to 100% full sunlight).The content of flavonoids and coumarins is positively correlated with light intensity.


Subject(s)
Biomass , Chlorophyll , Chloroplasts , Photosynthesis , Plant Leaves , Sunlight , Viola
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