ABSTRACT
SUMMARY: The aim of this systematic review was to assess the histological effects of platelet-rich plasma (PRP) on temporomandibular joint osteoarthritis (TMJ-OA) in animal models. A systematic search was performed using PubMed, WoS, EMBASE, Science Direct and SCOPUS databases. The inclusion criteria were experimental studies in animal models that evaluated the use of PRP as a treatment for TMJ-OA with or without arthrocentesis/arthroscopy. Comparison was made to a healthy control group or to other treatment. The variables evaluated were the histological effects of the treatments, characteristics of the primary articles, characteristics of the sample studied and the risk of bias. The systematic search identified 120 studies. Eventually 5 studies were included in the analysis. Four of the studies showed a statistically significant repair in joint tissues and improvement of cartilage thickness in animals treated with PRP. The global risk of bias was unclear. The results of this systematic review suggest that PRP treatment in TMJ-OA has benefits at the histological level in cartilage, articular disc and articular bone tissue in animal models. However, due to the low number of studies and the risk of bias, further research is needed to recommend its use.
El objetivo de esta revisión sistemática fue evaluar los efectos histológicos del plasma rico en plaquetas (PRP) en la osteoartritis de la articulación temporomandibular (ATM-OA) en modelos animales. Se realizó una búsqueda sistemática en las bases de datos PubMed, WoS, EMBASE, Science Direct y SCOPUS. Los criterios de inclusión fueron estudios experimentales en modelos animales que evaluaran el uso de PRP como tratamiento para la ATM-OA con o sin artrocentesis/ artroscopia. La comparación se realizó con un grupo de control sano o con otro tratamiento. Las variables evaluadas fueron los efectos histológicos de los tratamientos, las características de los artículos primarios, las características de la muestra estudiada y el riesgo de sesgo. La búsqueda sistemática identificó 120 estudios. Finalmente se incluyeron 5 estudios en el análisis. Cuatro de los estudios mostraron una reparación estadísticamente significativa en los tejidos articulares y una mejora del grosor del cartílago en los animales tratados con PRP. El riesgo global de sesgo fue incierto. Los resultados de esta revisión sistemática sugieren que el tratamiento con PRP en la ATM-OA tiene beneficios a nivel histológico en el cartílago, el disco articular y el tejido óseo articular en modelos animales. Sin embargo, debido al escaso número de estudios y al riesgo de sesgo, se necesitan investigaciones adicionales para recomendar su uso.
Subject(s)
Animals , Osteoarthritis/therapy , Temporomandibular Joint/anatomy & histology , Temporomandibular Joint Disorders/therapy , Platelet-Rich Plasma/physiology , Disease Models, AnimalABSTRACT
El objetivo de registrar los movimientos mandibulares es obtener parámetros relevantes que permitan evaluar el estado de la articulación temporomandibular (ATM) y de los músculos involucrados en la masticación. El movimiento mandibular se debe a un conjunto complejo de rotaciones y traslaciones tridimensionales realizadas por la ATM, limitado por los ligamentos y las superficies articulares de estas, y por la morfología y la alineación de los dientes, cuando la mandíbula se desplaza sobre estos límites, se llaman movimientos bordeantes mandibulares. El objetivo de este artículo es realizar una descripción actualizada de los movimientos mandibulares a través de articulografía electromagnética. Los movimientos mandibulares bordeantes se clasifican según el plano del espacio en que se muevan, de esta manera tenemos movimientos bordeantes en el plano sagital, en el plano horizontal y el plano frontal, y en cada plano dibujan un polígono distinto, llamados polígonos de Posselt. Estos polígonos pueden ser registrados mediante Articulografía electromagnética, gracias a esta tecnología también se pueden extraer algunos parámetros interesantes, como por ejemplo: la trayectoria total recorrida por la mandíbula al describir cada polígono, rangos de desplazamiento en cada plano, área total de cada polígono de Posselt. La apertura mandibular se mide como la distancia entre los márgenes incisales de los incisivos centrales superiores e inferiores en apertura máxima más la sobremordida. El análisis de esta es una parte importante del examen clínico en odontología, ya que una apertura limitada puede ser resultado de trastornos en la articulación temporomandibular, fibrosis oral submucosa, enfermedad reumática o trauma facial. Las mediciones tridimensionales que se obtienen gracias a la Articulografía electromagnética, son apropiados para determinar los rangos normales de apertura, su exactitud permite la realización de investigaciones en el área, abriendo un amplio campo en el análisis de los movimientos mandibulares.
SUMMARY: The objective of recording mandibular movements is to obtain relevant parameters that allow the evaluation of the state of the temporomandibular joint (TMJ) and of the muscles involved in mastication. Mandibular movement is due to a complex set of three-dimensional rotations and translations performed by the TMJ, limited by the ligaments and their articular surfaces, and by the morphology and alignment of the teeth, when the mandible moves over these limits, they are called mandibular border movements. The aim of this article is to provide an updated description of mandibular movements through electromagnetic articulography. Mandibular border movements are classified according to the plane of space in which they move, thus we have border movements in the sagittal plane, in the horizontal plane and the frontal plane, and in each plane they draw a different polygon, called Posselt polygons. These polygons can be recorded by electromagnetic articulography, thanks to this technology some interesting parameters can also be extracted, such as: the total trajectory covered by the mandible when describing each polygon, displacement ranges in each plane, total area of each polygon of Posselt. Mandibular opening is measured as the distance between the incisal edges of the upper and lower central incisors at maximum opening plus the overbite. The analysis of mandibular opening is an important part of the clinical examination in dentistry as a preliminary evaluation, since limited opening can be the result of temporomandibular joint disorders, submucous oral fibrosis, rheumatic disease or facial trauma. The three-dimensional measurements that are obtained thanks to the electromagnetic Articulography, are appropriate to determine the normal ranges of opening, its accuracy allows the realization of investigations in the area, opening a wide field in the analysis of mandibular movements. Analysis of mandibular opening is an important part of the clinical examination in dentistry, since limited opening can be the result of temporomandibular joint disorders, oral submucous fibrosis, rheumatic disease, or facial trauma. Analysis of mandibular opening is an important part of the clinical examination in dentistry, since limited opening can be the result of temporomandibular joint disorders, oral submucous fibrosis, rheumatic disease, or facial trauma. The three-dimensional measurements that are obtained thanks to the electromagnetic Articulography, are appropriate to determine the normal ranges of opening, its accuracy allows the realization of investigations in the area, opening a wide field in the analysis of mandibular movements.
Subject(s)
Humans , Temporomandibular Joint/physiology , Electromagnetic Phenomena , Mandible/physiologyABSTRACT
Disfunção Temporomandibular é um termo utilizado para indicar alterações e doenças das articulações temporomandibulares (ATM) e estruturas anexas responsáveis por sua função. Prevalente na população geral, seus sintomas causam desconforto e limitação da função mandibular, repercutindo diretamente na qualidade de vida de seus portadores. Dentre as alterações que compõem este grupo de doenças, destacam-se os desarranjos internos da ATM, para os quais o tratamento cirúrgico pode estar indicado. A Artroscopia da ATM, procedimento diagnóstico e terapêutico caracterizado pela introdução de óticas de pequeno calibre nos compartimentos articulares vem ganhando espaço e indicação como primeira opção terapêutica devido aos seus bons resultados e mínima invasividade. No entanto, sua dificuldade técnica, alto custo, necessidade de instrumentais específicos e sistema de videocirurgia ainda são fatores limitadores para a indicação desta pelos profissionais atuantes. Nosso objetivo foi validar, por meio de um estudo com simuladores realísticos validados e 10 examinadores qualificados de diferentes níveis de atuação, o uso de plataforma de adaptação de ótica para smartphone em artroscopia da ATM, afim de qualificar a resolução das imagens obtidas e grau de ergonomia durante seu uso por meio de classificação em três scores. Como resultados, obtivemos em geral, para qualidade da imagem 77,5% de nota máxima e 22,5% nota intermediaria e para ergonomia 62,5% de nota máxima e 37,5% de nota intermediaria. Concluímos que a plataforma é viável para a indicação de artroscopia de ATM em nível I e possível de ser utilizada em nível II.
Subject(s)
Arthroscopy , Temporomandibular Joint , SmartphoneABSTRACT
Chronic protracted TMJ dislocation refers to a condition in which the joint is displaced from its articulation and fixated in that position (open locked) without reduction. The Hippocratic Manoeuvre is usually unsuccessful with a high failure rate, making treatment of this condition very challenging. This article reports a case of TMJ dislocation not amenable to traditional closed reduction method but which was successfully treated using direct application of reduction forceps on the angle of the mandible. The technical aspects of the procedure and post-operative management were also highlighted.
Subject(s)
Temporomandibular Joint , Surgical Instruments , Mandibular DiseasesABSTRACT
Objective: the aim of this study was to evaluate the efficacy of ultrasonography in diagnosis of tempromandibular joint soft tissue injury after mandibular osteosynthesis. Material and Methods: ten male patients (20 joint) with age ranged between 20-28 years were collected from those attending the outpatient clinic of Oral and Maxillofacial Surgery Department, Al-Kuwait Hospital, Sana'a University. Patients were divided into two groups according to the number of fracture line in the mandible. All patients were randomly assigned to diagnosis of the soft tissue changes of temporomandibular joint by either ultrasonography or magnetic resonance image preoperatively, after 2 weeks and 3 months postoperatively. Results: preoperatively, there was moderate agreement between ultrasonography and magnetic resonance image in the diagnosis of abnormal findings in both groups, the difference was not statistically significant. In group I, ultrasonography of the temporomandibular joint didn't detect any abnormal findings after mandibular osteosynthesis, meanwhile, magnetic resonance image recorded abnormal findings 40% and 20% after 2 weeks and 3 months respectively. In group II, the diagnosis of abnormal findings was the same (80%) pre and postoperatively by using magnetic resonance image however, the percent ofabnormal findings was reduced from 60% preoperatively to 40% postoperatively by using ultrasonography. Conclusion: the ultrasonographic image was not able to identify or diagnosis the disc position changes after indirect trauma. However, it had to some extent a role in the identification and diagnosis of effusion in temporomandibular joint. (AU)
Objetivo: o objetivo deste estudo consistiu em avaliar a eficácia da ultrassonografia no diagnóstico de lesões nos tecidos moles da articulação temporomandibular após a osteossíntese mandibular. Material e Métodos: dez pacientes do sexo masculino (no total de 20 indivíduos) de idades entre 20 e 28 anos foram selecionados do serviço ambulatorial do Departamento de Cirurgia Oral e Maxilo-facial, Hospital Al-Kuwait, Universidade de Sana'a. Os indivíduos incluídos foram distribuídos em dois grupos, de acordo com o número de linhas de fratura presentes na mandíbula. Todos os pacientes foram aleatoriamente alocados e divididos, com base no diagnóstico das alterações dos tecidos moles da articulação temporomandibular por ultrassonografia ou ressonância magnética no pré-operatório e em intervalos de 2 semanas e 3 meses no pós-operatório. Resultados: no pré-operatório, houve uma concordância moderada entre a ultrassonografia e a ressonância magnética no diagnóstico de achados anormais em ambos os grupos; a diferença não foi estatisticamente significativa. No grupo I, a ultrassonografia da articulação temporomandibular não revelou quaisquer achados anormais após a osteossíntese mandibular, enquanto a ressonância magnética registou achados anormais em 40% e 20% dos casos após 2 semanas e 3 meses, respectivamente. No grupo II, o diagnóstico das anormalidades por ressonância magnética foi o mesmo (80%) no pré e pós-operatório; contudo, a percentagem de casos anormais por ultrassonografia foi reduzida de 60% no pré-operatório para 40% no pós-operatório. Conclusão: a imagem ultrassonográfica não foi capaz de detectar alterações de posição do disco após trauma indireto. Entretanto, em certa medida, contribuiu para a identificação e diagnóstico de efusão na articulação temporomandibular (AU)
Subject(s)
Humans , Temporomandibular Joint , Wounds and Injuries , Magnetic Resonance Spectroscopy , Ultrasonography , Mandibular FracturesABSTRACT
Aim: This study aimed to evaluate the relationship between clinical findings and some factors such as age, gender, and remaining teeth on the anatomy of the temporomandibular joint in order to diagnose normal variations from abnormal cases. Methods: In this cross-sectional study, cone-beam computed tomography (CBCT) images of 144 patients referring to Tabriz Dental School for various reasons were selected and evaluated. The different aspects of the clinical parameters and the morphology of the condyle were evaluated on coronal, axial, and sagittal views. The CBCT prepared using the axial cross-sections had been 0.5 mm in thickness. The sagittal cross-sections had been evaluated perpendicular to the lengthy axis of the condyle at a thickness of 1 mm and the coronal cross-sections had been evaluated parallel to the lengthy axis of the condyle at a thickness of 1 mm. Data were analyzed with descriptive statistical methods and t-test, chi-squared test, using SPSS 20. The significance level of the study was p < 0.05. Results: There was a significant relationship between the condyle morphology, number of the teeth, and mastication side (p = 0.040). There were significant relationships between the condyle morphology, age between 20-40, and occlusion class I on the all the three views (coronal, axial, sagittal) (p = 0.04), (p = 0.006), (p = 0.006). Also, significant relationships were found in the condyle morphology and location of pain according to age, the number of remaining teeth, and gender. (p = 0.046) (p = 0.027) (p = 0.035). Conclusion:There are significant relationships between the clinical symptoms and condyle morphology based on age, gender, and the number of remaining teeth. The clinical finding that has the most significant relationship between the condyle morphology, remaining teeth (9-16 teeth), all of the age range (20-80 year), and gender was mastication side
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Temporomandibular Joint/anatomy & histology , Cone-Beam Computed Tomography , Mandibular Condyle/anatomy & histologyABSTRACT
Objetivo: Avaliar os casos nos quais os pacientes apresentassem SVNP na ATM, incluindo aspectos clínicos, imaginológicos, histopatológicos e tratamento. Metodologia: Trata-se de uma revisão integrativa com dados obtidos nas bases de dados SciELO, PubMed, Medline e Lillacs entre 1982 e 2021, através dos descritores: "Case report", "Temporomandibular Joint", "Pigmented Villonodular Synovitis". Critérios de inclusão: estudos de relato de caso, textos completos disponíveis, idiomas de publicação em inglês, português ou espanhol. Critérios de exclusão: estudos sem presença de aspectos clínicos, relatos não localizados na ATM, artigos de metanálise, revisão sistemática e de literatura, ensaios clínicos, capítulos de livro, dissertações e teses. Dos 156 resultados, apenas 23 compuseram a revisão. Resultados: Como tratamento, a ressecção total através da cirurgia aberta é recomendada. Os sintomas mais comuns foram: dor na mastigação, trismo, dor pré auricular, dormência, parestesia, perca auditiva e inchaço da glândula parótida. Conclusão: Os aspectos imaginológicos revelam erosão de fossa glenóide e côndilo, histopatologicamente, células gigantes com depósito de hemossiderina, e o tratamento recomendado, ressecção via cirurgia aberta com posterior curetagem... (AU)
Objective: To evaluate the cases in which patients presented PVNS in the TMJ, including clinical, imaging, histopathological and treatment aspects. Methodology: This is an integrative review with data obtained from the SciELO, PubMed, Medline and Lillacs databases between 1982 and 2021, using the descriptors: "Case report", "Temporomandibular Joint", "Pigmented Villonodular Synovitis". Inclusion criteria: case report studies, full texts available, languages of publication in English, Portuguese or Spanish. Exclusion criteria: studies without the presence of clinical aspects, reports not located in the TMJ, meta analysis articles, systematic and literature reviews, clinical trials, book chapters, dissertations and theses. Of the 156 results, only 23 made up the review. Results: As a treatment, total resection through open surgery is recommended. The most common symptoms were: chewing pain, trismus, pre-auricular pain, numbness, paresthesia, hearing loss and parotid gland swelling. Conclusion: The imaging findings reveal erosion of the glenoid fossa and condyle, histopathologically, giant cells with hemosiderin deposits, and the recommended treatment, resection via open surgery with subsequent curettage... (AU)
Objetivo: Evaluar los casos en que los pacientes presentaron SVNP en la ATM, incluyendo aspectos clínicos, imagenológicos, histopatológicos y tratamiento. Metodología: Se trata de una revisión integradora con datos obtenidos de las bases de datos SciELO, PubMed, Medline y Lillacs entre 1982 y 2021, utilizando los descriptores: "Caso clínico", "Articulación temporomandibular", "Sinovitis villonodular pigmentada". Criterios de inclusión: estudios de casos clínicos, textos completos disponibles, idiomas de publicación en inglés, portugués o español. Criterios de exclusión: estudios sin aspectos clínicos, informes no localizados en la ATM, artículos de metanálisis, revisiones sistemáticas y de literatura, ensayos clínicos, capítulos de libros, disertaciones y tesis. De los 156 resultados, 23 conformaron la revisión. Resultados: Como tratamiento se recomienda la resección total mediante cirugía abierta. Los síntomas más frecuentes fueron: dolor masticatorio, trismus, dolor preauricular, entumecimiento, parestesia, hipoacusia e inflamación de glándula parótida. Conclusión: Los hallazgos imagenológicos revelan erosión de fosa glenoidea y cóndilo, histopatológicamente células gigantes con depósitos de hemosiderina y el tratamiento recomendado, resección abierta con posterior curetaje... (AU)
Subject(s)
Humans , Male , Female , Synovitis, Pigmented Villonodular/surgery , Temporomandibular Joint , Giant Cells , Synovitis, Pigmented Villonodular , Curettage , Glenoid CavityABSTRACT
Temporomandibular disorder (TMD) is recognized for its high prevalence, presenting characteristic signs and symptoms. Cervical spine pain is present in 70% of diagnosed TMD cases. Aim To verify if women with TMD present changes in isometric muscle strength in the scapula elevation. Methods This is an observational, cross-sectional study. Thirty-five women, aged 22.89±2.04 years, were divided into the TMD group (TMDG), diagnosed with TMD according to the DC/TMD, and control group (CG), with asymptomatic individuals. The volunteers accessed a online link by the smartphone in order to answer questions on personal data, the Fonseca Anamnestic Index (FAI), Neck Disability Index (NDI), and Masticatory preference. In all participants, evaluation of the force of the scapula elevation muscles was performed, using a load cell model MM-100 (Kratos® SP, Brazil). Data were analyzed descriptively using the maximum, mean, and standard deviation and a two-way ANCOVA test was applied for all variables. A significance level of 5% was considered. Results There were no statistically significant differences between the TMDG and CG for the maximal and mean muscle strength of scapular elevation. There were statistically significant differences in FAI (p <0.001*) between the CG and the TMDG. Conclusion Based on the results, it was not possible to confirm the hypothesis that women diagnosed with TMD present lower isometric strength during scapular elevation (right/left).
Subject(s)
Humans , Female , Adult , Scapula , Temporomandibular Joint , Muscle Strength , Isometric ContractionABSTRACT
O complexo de desordens hiperostóticas é uma condição rara e autolimitante, que tem as mesmas características histopatológicas, que cursa com proliferação óssea de caráter não neoplásico. Acomete cães jovens de raças distintas, com variabilidade quanto ao tipo de proliferação óssea e quanto aos ossos acometidos. O complexo é composto pela osteopatia craniomandibular, hiperostose da calota craniana e osteodistrofia hipertrófica. Podendo estar presente nos ossos da calota craniana, mandíbulas, coluna cervical e esqueleto apendicular. O presente relato, descreveu o quadro de uma cadela, da raça American Bully, não castrada, três meses de idade, que foi atendida com queixa de aumento de volume doloroso das mandíbulas, hiporexia e sialorreia há 15 dias, apresentando ao exame físico, amplitude de movimento diminuída e sensibilidade dolorosa da articulação temporomandibular, espessamento firme bilateral do crânio em região de fossa temporal, espessamento palpável de consistência firme das mandíbulas e crepitação respiratória. Após avaliação clínica e realização de exames complementares, chegou-se ao diagnóstico presuntivo, de complexo de desordens hiperostóticas. Foi instituído como conduta terapêutica o suporte analgésico, sendo eficaz para a manutenção das necessidades fisiológicas até a paciente alcançar a fase adulta. O prognóstico para esta paciente foi considerado bom, uma vez que não havia indícios de anquilose da articulação temporomandibular e/ou manifestações neurológicas.
The complex of hyperostotic disorders is a rare and self-limiting condition, which has the same histophatological characteristics, which courses with non-neoplastic bone proliferations. It affects young dogs of different breeds, with variability the bones affected. The complex is composed of craniomandibular osteopathy, calvarial hyperostotic syndrome and hypertrophic osteodystrophy. It may be present in the bones of the skullcap, jaws, cervical spine and appendicular skeleton. The present report describes the condition of a female dog, American Bully breed, entire, three months old, with a complaint of painful swelling of the jaws, hyporexia and drooling for 15 days, presenting on physical examination, reduced amplitude and pain of the temporomandibular joint, bilateral firm thickening of the skull in the temporal fossa region, palpable firm-consistent thickening of the mandibles and respiratory crackle. After clinical evaluation and complementary tests, a presumptive diagnosis of hyperostotic disorders complex was reached. It was instituted pain management as a treatment, being effective for the maintenance of physiological needs until the patient reaches the adulthood. The prognosis for this patient was considered good, since there was no evidence of temporomandibular joint ankylosis and/or neurological manifestations.
Subject(s)
Animals , Dogs , Temporomandibular Joint/abnormalities , Bone Development , Hyperostosis/veterinary , Craniomandibular Disorders/veterinary , Dogs/abnormalities , Facial Bones/pathology , Analgesics/therapeutic useABSTRACT
A articulação temporomandibular está vunerável a várias condições de anormalidades já bastante conhecidas, dentre elas, o deslocamento do disco articular sem redução, considerado pela literatura o mais comum das patologias desta região. A deterioração do quadro pode ser um indicativo da necessidade cirúrgica. Em específico, no deslocamento de disco sem redução, o reposicionamento definitivo pode ser adquirido através de discopexia e artrocentese. O presente trabalho tem como objetivo relatar um caso clínico de deslocamento de disco articular bilateral sem redução, apresentando a importância da fisioterapia associada à abordagem cirúrgia na recuperação da função mandibular, bem como, reforçar a importância de uma abordagem conjunta entre análise clínica e imaginológica para resolução de casos. Paciente feminino cursando com diversos sintomas em face e pescoço de forma progressiva ao longo de dois anos foi submetida a cirurgia na articulação temporo-mandibular, onde foi feita a discopexia através de ancoragem dos discos articulares com parafusos. A avaliação física, assim como, a imaginológica, ajudaram na confirmação do diagnóstico. A abordagem cirurgica adotada no tratamento deste caso foi descrita na literatura desde o final do século XIX. Conclui-se que, o método utilizado no tratamento do deslocamento de disco sem redução deve ser baseado nos sinais e sintomas do paciente, cuja abordagem deve ser readequada de acordo com as mudanças do quadro apresentado. Nesta análise, a abordagem cirúrgica associada à fisioterapia específica para as estruturas musculoesquelética da face trouxeram resultados positivos(AU)
The temporomandibular joint is responsible for several well-known conditions of abnormalities, among them, the joint disc displacement without reduction, considered by the literature the most common pathology of this region. Deterioration of the condition may be indicative of surgical need. Specifically, in displacement disc without reduction, definitive repositioning can be achieved through discopexy and arthrocentesis. The aim of the present study is to report a case of unilateral articular disc displacement without reduction, as well the importance of physiotherapy associated with the surgical approach in the recovery of mandibular function, as well as reinforcing the importance of a joint approach between clinical and imaging analysis for case resolution. Female patient with several symptoms in the face and neck progressively over two years, underwent surgery in the temporomandibular joint, where discopexy was performed by anchoring the articular discs with screws. The physical assessment, as well as the imaging, helped to confirm the diagnosis. The surgical approach adopted in the treatment of this case has been described in the literature since the end of the 19th century. In conclusion, the method used to treat articular disc displacement without reduction should be based on the patient's signs and symptoms, whose approach should be readjusted according to the changes in the presented picture. In this analysis, the surgical approach associated with specific physiotherapy for the musculoskeletal structures of the face brought positive results(AU)
Subject(s)
Humans , Female , Adult , Temporomandibular Joint Disc , Temporomandibular Joint Disc/injuries , Joint Dislocations , Temporomandibular Joint/injuries , Physical Therapy Modalities , Temporomandibular Joint Disc/surgery , Temporomandibular Joint Disc/diagnostic imaging , ArthrocentesisABSTRACT
Introdução: As limitações das terapias atuais para doenças degenerativas da articulação temporomandibular (ATM) levaram ao aumento do interesse em estratégias regenerativas. A engenharia de tecidos (ET), combinando células-tronco, arcabouços e fatores de crescimento, pode fornecer uma substituição biológica funcional e permanente das estruturas da ATM, além de prevenir o avanço de doenças degenerativas. Objetivo: Este artigo descreve as perspectivas atuais da ET das estruturas da ATM em modelos animais. Metodologia: As abordagens da ET foram categorizadas de acordo com as estruturas primárias da ATM: 1) o disco articular, 2) o côndilo mandibular e 3) a fossa glenóide e eminência articular. Resultados: As áreas com a maior quantidade de estudos são o côndilo mandibular e disco articular, em estudos que abordam o uso de arcabouços tridimensionais, de origem sintética e/ou natural, podendo ou não estar associados a células tronco (diferenciadas ou não) e a fatores de crescimento. Conclusão: A ET da ATM ainda é uma área relativamente nova, em desenvolvimento e em constante avanço. Os avanços tecnológicos desenvolvidos nessa área têm o potencial de auxiliar no desenvolvimento de terapias mais eficientes e menos invasivos... (AU)
Introducción: Las limitaciones de las terapias actuales para las enfermedades degenerativas de la articulación temporomandibular (ATM) han llevado a un mayor interés en las estrategias regenerativas. La ingeniería de tejidos, que combina células, andamios y factores de crecimiento, puede proporcionar un reemplazo biológico funcional y permanente de las estructuras de la ATM, además de prevenir el avance de enfermedades degenerativas. Objetivo: Este artículo describe las perspectivas actuales de la ingeniería de tecidos de las estructuras de la ATM en modelos animales. Metodología: Los enfoques de ingeniería de tejidos se clasificaron según las estructuras primarias de la ATM: 1) el disco articular, 2) el cóndilo mandibular y 3) la fosa glenoidea y la eminencia articular. Resultados: Las áreas con mayor número de estudios son el cóndilo mandibular y el disco articular, en estudios que abordan el uso de estructuras tridimensionales, de origen sintético y/o natural, que pueden o no estar asociadas a células (diferenciadas o no) y con factores de crecimiento. Conclusión: La ingeniería de tejidos de la ATM es todavía un área relativamente nueva, en desarrollo y em constante avance. Los avances tecnológicos desarrollados en esta área tienen el potencial de ayudar en el desarrollo de terapias más eficientes y menos invasivas... (AU)
Introduction: The limitations of current therapies for degenerative diseases of the temporomandibular joint (TMJ) have led to increased interest in regenerative strategies. Tissue engineering (TE), combining stem cells, scaffolds, and growth factors, can provide a functional and permanent biological replacement of TMJ structures, in addition to preventing the advancement of degenerative diseases. Aim: This article describes current TE perspectives of TMJ structures in animal models. Methods: TE approaches were categorized according to the primary TMJ structures: 1) the articular disc, 2) the mandibular condyle, and 3) the glenoid fossa and articular eminence. Results: The areas with the greatest number of studies are the mandibular condyle and articular disc, in studies that address the use of three-dimensional scaffolds, of synthetic and/or natural origin, which may or may not be associated with stem cells (differentiated or not) and with growth factors. Conclusion: TE of the TMJ is still a relatively new, developing, and constantly advancing area. The technological advances developed in this area have the potential to assist in the development of more efficient and less invasive therapies... (AU)
Subject(s)
Humans , Male , Female , Stem Cells , Temporomandibular Joint/surgery , Tissue Engineering , Mandibular Condyle , Technological DevelopmentABSTRACT
Introducción: Los trastornos temporomandibulares constituyen una condición dolorosa que afecta los músculos de la masticación, la articulación temporomandibular, así como varias estructuras anatómicas del sistema estomatognático. Objetivo: Evaluar la efectividad de la electroacupuntura en pacientes con síndrome de dolor miofacial asociado a disfunción de la articulación temporomandibular. Métodos: Se realizó un estudio cuasiexperimental de intervención terapéutica en 80 pacientes asistidos en el Hospital General Docente Dr. Juan Bruno Zayas Alfonso de Santiago de Cuba, desde noviembre del 2018 hasta igual mes de 2021, quienes padecían dolor miofacial por disfunción en las articulaciones temporomandibulares. Estos fueron asignados de forma alterna en dos grupos terapéuticos de 40 integrantes cada uno: el de estudio, al que se le aplicó electroacupuntura, y el de control, el cual recibió medicación farmacológica convencional; luego, se les fue evaluando clínicamente al tercero, quinto, séptimo y décimo días de iniciadas las terapias. Las variables fueron procesadas estadísticamente aplicando el porcentaje como medida de resumen y la prueba de la Χ2 para estimar diferencias en cuanto al tiempo promedio de buena evolución, con un nivel de significación de 0,05. Resultados: Antes de comenzar los tratamientos, el dolor era intenso en la mayoría de los pacientes de ambos grupos; sin embargo, al tercer día de iniciada la intervención terapéutica, la evolución había sido buena en 45,0 % del grupo de estudio y 32,5 % del grupo de control; al quinto día este porcentaje había aumentado a 60,0 en los que recibieron electroacupuntura, pero se mantuvo igual en los que fueron tratados convencionalmente. Al finalizar la intervención se había logrado la recesión o el alivio del dolor miofacial en 97,5 % de los casos y en 90,0 % de los controles. Conclusiones: La electroacupuntura resultó clínicamente más efectiva para paliar el dolor miofacial producido por los trastornos temporomandibulares, con un menor tiempo promedio de buena respuesta terapéutica.
Introduction: The temporomandibular disorders constitute a painful condition that affects the mastication muscles, the temporomandibular joint, as well as several anatomical structures of the stomatognathic system. Objective: To evaluate the effectiveness of electroacupuncture in patients with syndrome of miofacial pain associated with temporomandibular joint dysfunction. Methods: A quasi-experiment study of therapeutic intervention in 80 patients assisted in Dr. Juan Bruno Zayas Alfonso Teaching General Hospital from Santiago de Cuba, was carried out from November, 2018 to the same month in 2021, who suffered from miofacial pain due to dysfunction in the temporomandibular joint. These were assigned in an alternating way in two therapeutic groups of 40 members each one: that of study, to which electroacupuncture was applied, and that of control, which received conventional pharmacological medication; then, they were clinically evaluated at the third, fifth, seventh and tenth days after the therapy. The variables were statistically processed applying the percentage as summary measure and the chi-square test to estimate differences as for the average time of good evolution, with a level of significance of 0.05. Results: Before beginning the therapy, the pain was intense in most of the patients of both groups; however, at the third day of the therapies, the evolution had been good in 45.0 % of the study group and 32.5 % of the control group, and the fifth day this percentage had increased at 60.0 in those that received electroacupuncture, but stayed equally in those that were treated conventionally. When concluding the intervention recession or relief of the miofacial pain in 97.5 % of the cases and in 90.0 % of the controls was achieved. Conclusions: The electroacupuncture was clinically more effective than the conventional medication to palliate the miofacial pain caused by the temporomandibular disorders, with a less average time of good therapeutic response.
Subject(s)
Temporomandibular Joint , Temporomandibular Joint Disorders , Electroacupuncture , Facial PainABSTRACT
Introdução: As limitações das terapias atuais para doenças degenerativas da articulação temporomandibular (ATM) levaram ao aumento do interesse em estratégias regenerativas. A engenharia de tecidos (ET), combinando células-tronco, arcabouços e fatores de crescimento, pode fornecer uma substituição biológica funcional e permanente das estruturas da ATM, além de prevenir o avanço de doenças degenerativas. Objetivo: Este artigo descreve as perspectivas atuais da ET das estruturas da ATM em modelos animais. Metodologia: As abordagens da ET foram categorizadas de acordo com as estruturas primárias da ATM: 1) o disco articular, 2) o côndilo mandibular e 3) a fossa glenóide e eminência articular. Resultados: As áreas com a maior quantidade de estudos são o côndilo mandibular e disco articular, em estudos que abordam o uso de arcabouços tridimensionais, de origem sintética e/ou natural, podendo ou não estar associados a células tronco (diferenciadas ou não) e a fatores de crescimento. Conclusão: A ET da ATM ainda é uma área relativamente nova, em desenvolvimento e em constante avanço. Os avanços tecnológicos desenvolvidos nessa área têm o potencial de auxiliar no desenvolvimento de terapias mais eficientes e menos invasivos... (AU)
Introducción: Las limitaciones de las terapias actuales para las enfermedades degenerativas de la articulación temporomandibular (ATM) han llevado a un mayor interés en las estrategias regenerativas. La ingeniería de tejidos, que combina células, andamios y factores de crecimiento, puede proporcionar un reemplazo biológico funcional y permanente de las estructuras de la ATM, además de prevenir el avance de enfermedades degenerativas. Objetivo: Este artículo describe las perspectivas actuales de la ingeniería de tecidos de las estructuras de la ATM en modelos animales. Metodología: Los enfoques de ingeniería de tejidos se clasificaron según las estructuras primarias de la ATM: 1) el disco articular, 2) el cóndilo mandibular y 3) la fosa glenoidea y la eminencia articular. Resultados: Las áreas con mayor número de estudios son el cóndilo mandibular y el disco articular, en estudios que abordan el uso de estructuras tridimensionales, de origen sintético y/o natural, que pueden o no estar asociadas a células (diferenciadas o no) y con factores de crecimiento. Conclusión: La ingeniería de tejidos de la ATM es todavía un área relativamente nueva, en desarrollo y en constante avance. Los avances tecnológicos desarrollados en esta área tienen el potencial de ayudar en el desarrollo de terapias más eficientes y menos invasivas... (AU)
Introduction: The limitations of current therapies for degenerative diseases of the temporomandibular joint (TMJ) have led to increased interest in regenerative strategies. Tissue engineering (TE), combining stem cells, scaffolds, and growth factors, can provide a functional and permanent biological replacement of TMJ structures, in addition to preventing the advancement of degenerative diseases. Aim: This article describes current TE perspectives of TMJ structures in animal models. Methods: TE approaches were categorized according to the primary TMJ structures: 1) the articular disc, 2) the mandibular condyle, and 3) the glenoid fossa and articular eminence. Results: The areas with the greatest number of studies are the mandibular condyle and articular disc, in studies that address the use of three-dimensional scaffolds, of synthetic and/ or natural origin, which may or may not be associated with stem cells (differentiated or not) and with growth factors. Conclusion: TE of the TMJ is still a relatively new, developing, and constantly advancing area. The technological advances developed in this area have the potential to assist in the development of more efficient and less invasive therapies... (AU)
Subject(s)
Animals , Stem Cells , Temporomandibular Joint , Cells , Models, Animal , Tissue Engineering , Intercellular Signaling Peptides and Proteins , Growth and Development , Biological Products , Technological Development , Mandibular CondyleABSTRACT
Introducción: la luxación de la articulación temporomandibular es un desplazamiento del cóndilo fuera de sus posiciones funcionales dentro de la fosa articular y la eminencia articular, la cual ocasiona una pérdida completa de la función articular. La luxación crónica es toda luxación aguda que progresa sin un tratamiento específico y que puede ser de carácter recurrente. La eminectomía es un tratamiento quirúrgico definitivo contra la luxación crónica de articulación temporomandibular. Objetivo: reportar el caso clínico de un paciente masculino, de la tercera década de su vida, con diagnóstico de luxación crónica de la articulación temporomandibular de cinco meses de evolución y presentar una revisión actualizada de la literatura sobre este procedimiento quirúrgico. Caso clínico: el paciente fue tratado quirúrgicamente con eminectomía bilateral. Discusión: la eminectomía es un procedimiento quirúrgico controversial; sin embargo, recientes investigaciones lo catalogan como seguro y efectivo. Conclusión: el caso clínico presentado muestra un buen resultado.
Background: Temporo-mandibular joint dislocation is a displacement of the condyle, out of its functional positions within the articular fossa and articular eminence, causing a complete loss of joint function. Chronic dislocation is any acute dislocation that progresses without specific treatment and that can be recurrent. Eminectomy is a definitive surgical treatment for chronic temporomandibular joint dislocation. Objective: To report the clinical case of a male patient in the third decade of his life with a diagnosis of chronic dislocation of the temporomandibular joint of 5 months of evolution and to carry out an updated review of the literature on this surgical procedure. Case Report: The patient was treated surgically with bilateral eminectomy. Discussion: Eminectomy is a controversial surgical procedure; recent research classifies it as safe and effective. Conclusion: The presented clinical case shows a good result.
Subject(s)
Humans , Male , Adult , Joint Dislocations , Temporomandibular Joint , Temporomandibular Joint DisordersABSTRACT
SUMMARY: The temporomandibular joint (TMJ) is the joint between the mandibular condyles, the mandibular fossa and the articular tubercle of the temporal bone. TMJ has been described as a "bicondylar" joint, a term that in current literature is used in multiple and dissimilar contexts. We present a scoping review of the term "bicondylar" as a descriptive term for TMJ in the scientific literature of the last 5 years. After selection according to the inclusion/exclusion criteria, 24 articles were selected for further analysis. The countries with the most publications were Brazil, India and Turkey with 3 articles each. Seven articles (29.17 %) were published by Spanish- speaking authors, six of these written in Spanish. Regarding the use of the term "bicondylar", 50 % of the articles referred to this term but did not explain it; 25 % cited this term to refer to the location in the left and right mandibular condyles; and 25 % the articles use the term and explain it according to the morphology of the articular surfaces. Discrepancies were also detected regarding as to how to consider TMJ: 54.17 % considered that TMJ is a single joint between a single bone (the jaw) and two bones of the cranium, while 45.83 % considered that TMJ are actually two different TMJs that work at the same time. We suggest discussing the appropriate use of the term "bicondylar" to avoid confusion and to be able to adapt and satisfy the needs of both anatomists and clinicians.
RESUMEN: La articulación temporomandibular (ATM) es la articulación entre los cóndilos mandibulares con la fosa mandibular y el tubérculo articular del hueso temporal. La ATM ha sido descrita como una articulación "bicondílea", término que en la literatura actual se utiliza en múltiples y disímiles contextos. Presentamos una revisión con búsqueda sistemática del término "bicondíleo" como término descriptivo de la ATM en la literatura científica de los últimos 5 años. Siguiendo criterios de inclusión/exclusión, se seleccionaron 24 artículos para su posterior análisis. Los países con más publicaciones fueron Brasil, India y Turquía con 3 artículos cada uno. Siete artículos (29,17 %) fueron publicados por autores de habla hispana, seis de ellos escritos en español. En cuanto al uso del término "bicondilar", el 50 % de los artículos se refieren a él, pero no lo explican; un 25 % citó este término para referirse a la ubicación en los cóndilos mandibulares izquierdo y derecho; y el 25 % de los artículos utilizan el término y lo explican según la morfología de las superficies articulares. También se detectaron discrepancias en cuanto a cómo considerar la ATM: el 54,17 % consideró que la ATM es una única articulación entre un solo hueso (la mandíbula) y dos huesos del cráneo, mientras que el 45,83 % consideró que la ATM son en realidad dos ATM diferentes que funcionan al mismo tiempo. Se sugiere discutir el uso adecuado del término "bicondilar" para evitar confusiones y poder adaptar y satisfacer las necesidades tanto de anatomistas como de clínicos.
Subject(s)
Humans , Temporomandibular Joint/anatomy & histology , Terminology as Topic , Mandibular CondyleABSTRACT
Abstract Objective: To assess the association between temporomandibular disorder (TMD) with sociodemographic factors, health-related factors, and oral conditions in adolescents. Material and Methods: This cross-sectional study was developed with 89 adolescents between 13 to 18 years. TMD diagnosis was obtained by the Research Diagnostic Criteria for Temporomandibular Disease (RDC/TMD) Axis I. Diagnoses of chronic pain, depression, presence of non-specific physical symptoms, including pain and anxiety, were obtained by the RDC/TMD Axis II. The feeling of happiness was measured by the Subjective Happiness Scale. Socio-economic and demographic characteristics were collected through self-administered questionnaires. Patients were examined for dental caries, dental trauma, malocclusion, and tooth wear. Parents answered a sociodemographic, economic, and general health questionnaire. Data were submitted to descriptive statistics, and a logistic regression model was used to assess the association between TMD and the socio-economic, demographic, health-related, and clinical variables. Results: TMD prevalence was 42%. TMD was associated to skin color (p=0.040), use of medications in the past year (p = 0.020) and previous dental trauma (p=0.030). Also, it tended to be associated with the presence of probable awake bruxism (p=0.053). Conclusion: Sociodemographic factors, health-related factors, and oral conditions play a role in TMD, with nonwhite adolescents, those who had used medications in the past year and/or had previous dental trauma having a greater chance of present this disorder (AU).
Subject(s)
Humans , Male , Female , Adolescent , Temporomandibular Joint , Temporomandibular Joint Dysfunction Syndrome/epidemiology , Adolescent , Sociodemographic Factors , Temporomandibular Joint Disorders/diagnosis , Logistic Models , Cross-Sectional Studies/methods , Surveys and QuestionnairesABSTRACT
Resumo Diversas manobras já foram descritas para o acesso ao segmento distal cervical da artéria carótida interna ou à bifurcação carotídea alta; entretanto, há divergências na sistematização dessas técnicas. O objetivo deste estudo é revisar as técnicas descritas e propor um protocolo prático que auxilie na seleção da técnica mais adequada para cada caso. Para isso, foi realizada uma busca nas bases de dados PubMed Central, Biblioteca Virtual em Saúde e SciELO por artigos sobre o tema, em língua inglesa ou portuguesa, publicados entre os anos de 1980 e 2021. Entre as manobras descritas, parece razoável que as duas etapas iniciais sejam a abordagem ao músculo esternocleidomastóideo, seguida pela secção/retração do ventre posterior do músculo digástrico. Caso necessário, a subluxação mandibular temporária unilateral é um recurso adicional e preferível à divisão do aparato estiloide, devido ao menor potencial de morbidade. Exposições ainda mais amplas podem ser obtidas com as osteotomias mandibulares.
Abstract Several different maneuvers have been described for obtaining access to the distal cervical segment of the internal carotid artery or to a high carotid bifurcation. However there are different approaches to systematization of these techniques. The objective of this study is to review the techniques described and propose a practical protocol to support selection of the most appropriate technique for each case. The review is based on the results of database searches on PubMed Central, the Virtual Health Library (BVSalud), and SciELO for articles on the subject published in English or Portuguese from 1980 to 2021. Among the different maneuvers described, it appears reasonable that the first two steps should be to obtain access at the sternocleidomastoid muscle, followed by section or retraction of the digastric muscle posterior belly. If needed, temporary unilateral mandibular subluxation is an additional resource that is preferable to division of the styloid apparatus process, because of its lesser potential for morbidity. Even wider exposure can be obtained using mandibular osteotomies.
Subject(s)
Vascular Surgical Procedures/methods , Carotid Artery, Internal/surgery , Temporomandibular Joint/surgery , Carotid Artery, Internal/anatomy & histology , Mandibular Osteotomy/methodsABSTRACT
Los contactos mediotrusivos son aquellos contactos oclusales que se encuentran entre las vertientes in- ternas de las cúspides linguales maxilares y las inter- nas de las cúspides bucales mandibulares del lado de no trabajo durante los movimientos de lateralidad. Estos contactos mediotrusivos podría desencadenar trastornos temporomandibulares, afectando la oclu- sión y la articulación temporomandibular. El objetivo de este estudio es analizar las caracterís- ticas y la relación entre los contactos mediotrusivos con la articulación temporomandibular y la oclusión en pacientes que consultan al Servicio de Oclusión y ATM del Hospital Odontológico de la Facultad de Odontología de la Universidad Nacional del Nordeste (AU)
Mediotrusive contacts are those occlusal contacts that are found between the internal slopes of the maxillary lingual cusps and the internal slopes of the mandibular buccal cusps on the non-working side during laterality movements. These mediotrusive contacts could trigger temporomandibular disorders affecting occlusion and temporomandibular joint. The objective of this study was to analyze the characteristics and relationship of mediotrusive contacts with occlusion and the temporomandibular joint, in patients who consult the Occlusion and TMJ Service of the Dental Hospital of the Faculty of Dentistry of the National University of the Northeast (AU)
Subject(s)
Humans , Male , Female , Adult , Facial Pain , Temporomandibular Joint Disorders , Dental Occlusion , Argentina , Schools, Dental , Temporomandibular Joint/physiopathology , Prospective Studies , Dental Service, Hospital , Masticatory Muscles/physiopathologyABSTRACT
ABSTRACT Introduction: Temporomandibular disorder (TMD) refers to a group of conditions that compromise the harmonious movement and function of the temporomandibular joint, masticatory muscles, and associated structures. The etiopathogenesis of TMD is multifactorial but not well-understood, with the role of genetic factors still being unclear. Objective: This review aims to summarize the results of studies that evaluated TNF-α levels and the -308G/A TNF-α polymorphism in TMD patients. This study emphasizes the importance of a more selective treatment involving TNF-α inhibitors that can potentially reduce inflammation and pain, and improve quality of life. Methods: The MEDLINE/PubMed database, Cochrane Library, and Web of Science database were searched for case-control studies published until September 2020 that compared levels of TNF-α or presence of its -308G/A polymorphism in TMD patients and healthy individuals. Results: Six case-control studies were identified with a total of 398 TMD patients, aged between 12 and 78 years. The control group consisted of 149 subjects, aged between 18 and 47 years. The occurrence of TMD was predominant in females. Majority of studies found high TNF-α levels in TMD patients, compared to the control group. One of these studies found a positive correlation between the GA genotype and the development of TMD. Conclusion: Majority of the TMD patients showed elevated TNF-α levels, and a possible explanation for this could be the presence of the -308G/A polymorphism.
RESUMO Introdução: A disfunção temporomandibular (DTM) é definida como um grupo de alterações que comprometem a articulação temporomandibular, os músculos mastigatórios e as estruturas associadas. A etiopatogenia da DTM é multifatorial, e o papel dos fatores genéticos permanece obscuro. Objetivo: A presente revisão teve como objetivo descrever as contribuições de estudos que avaliaram os níveis de TNF-α e o polimorfismo -308 G/A em pacientes com DTM. Esse estudo enfatizou a importância de um tratamento mais completo envolvendo os inibidores do TNF-α que podem potencialmente reduzir a inflamação e a dor, contribuindo para melhorar a qualidade de vida do paciente. Métodos: As pesquisas foram realizadas nas bases de dados MEDLINE/PubMed, Cochrane Library e Web of Science, em busca de estudos de caso-controle publicados até setembro de 2020 que avaliassem os níveis de TNF-α e seu polimorfismo -308 G/A nos pacientes com DTM e em controles saudáveis. Resultados: Seis estudos de caso-controle foram identificados, com um total de 398 pacientes com DTM, e a idade variou de 12 a 78 anos. O grupo controle consistiu de 149 indivíduos e sua idade variou, aproximadamente, de 18 a 47 anos. O sexo feminino foi predominante. A maioria das pesquisas encontrou níveis elevados de TNF-α nos pacientes, em comparação com os controles. Um estudo encontrou uma associação positiva entre o genótipo GA e o desenvolvimento de DTM. Conclusão: A maioria dos pacientes com DTM demonstrou predisposição a uma maior produção de TNF-α, e isso poderia ser explicado pela presença do polimorfismo -308 G/A.