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1.
Rev. colomb. cancerol ; 24(3): 130-139, jul.-set. 2020. graf
Article in Spanish | LILACS | ID: biblio-1144332

ABSTRACT

Resumen El tumor desmoplásico de célula redonda y pequeña (TDCRP) es una patología neoplásica maligna agresiva y poco común. Afecta predominantemente a hombres entre la segunda y tercera década de la vida. Los pacientes que la padecen tienen un pronóstico pobre, con una supervivencia global a 5 años de hasta el 30%. Por lo general se presenta como una masa en la cavidad abdominal, frecuentemente multifocal. Para su tratamiento se recomienda un enfoque multimodal con cirugía, quimioterapia y radioterapia. Poco más de 20 casos de TDCRP a nivel testicular/paratesticular se han reportado en la literatura. A continuación, se presenta un caso ilustrativo en esta localización, se discute el caso y se realiza revisión de la literatura.


Abstract Desmoplastic small round cell tumor (DSRCT) is an aggressive and rare malignant neoplasm. It mainly affects young men in their twenties and thirties. Patients with it have a poor prognosis, with a 5-year survival rate of up to 30%. It generally presents as a mass in the abdominal cavity, often multifocal. A multimodal approach is recommended for its treatment, with surgery, chemotherapy, and radiotherapy. Just over 20 cases of testicular/paratesticular DSRCT have been reported in the literature. Below, we present an illustrative case in this location, we discuss the case and review the literature.


Subject(s)
Humans , Male , Adult , Retroperitoneal Neoplasms/diagnosis , Retroperitoneal Neoplasms/therapy , Desmoplastic Small Round Cell Tumor/diagnosis , Desmoplastic Small Round Cell Tumor/therapy , Genital Neoplasms, Male/diagnosis , Genital Neoplasms, Male/therapy , Testicular Neoplasms/diagnosis , Testicular Neoplasms/therapy , Ganglia
2.
Int. braz. j. urol ; 46(1): 101-107, Jan.-Feb. 2020. tab, graf
Article in English | LILACS | ID: biblio-1056359

ABSTRACT

ABSTRACT Purpose: To assess the relationship between testicular germ cell tumors (TGCT) and neutrophil to lymphocyte ratio (NLR) and to determine whether this ratio can be used as a serum tumor marker. Material and Methods: Sixty-one patients with testicular germ cell tumors were included into the study. Patients were grouped as localized and non-localized. Histologically patients were categorized as seminoma and nonseminomatous germ cell tumors. Complete blood cell count was measured the day before surgery and at the postoperative 1st month. Preoperative and postoperative mean NLR values were compared. Results: Thirty-six patients (59%) had seminomas and 25 patients (41%) had nonseminomatous testicular cancer. Forty-five patients (73.8%) had localized and 16 patients (26.2%) had non-localized testicular cancer. There was a statistically significant difference between preoperative and postoperative mean NLR of the localized patients (p=0.001) but no such difference was detected for non-localized patients (p=0.576). Nineteen patients with localized seminomas had normal preoperative serum tumor markers. There was a significant difference between preoperative and postoperative mean NLR in this group of patients (p=0.010). Twenty-six patients with localized tumors had preoperative increased serum tumor markers which normalized after orchiectomy. Mean NLR of these patients significantly decreased from 3.10±2.13 to 1.62±0.59 postoperatively (p=0.010). Conclusions: NLR appears to be a useful marker for TGCT. It is successful in predicting localized and non-localized disease in early postoperative period.


Subject(s)
Humans , Male , Adult , Aged , Young Adult , Testicular Neoplasms/blood , Lymphocytes , Seminoma/blood , Neoplasms, Germ Cell and Embryonal/blood , Neutrophils , Postoperative Period , Reference Values , Testicular Neoplasms/surgery , Testicular Neoplasms/diagnosis , Preoperative Care , Orchiectomy , Biomarkers, Tumor/blood , Reproducibility of Results , Retrospective Studies , Sensitivity and Specificity , Seminoma/surgery , Seminoma/diagnosis , Neoplasms, Germ Cell and Embryonal/surgery , Neoplasms, Germ Cell and Embryonal/diagnosis , Statistics, Nonparametric , Lymphocyte Count , Middle Aged
3.
Rev. cir. (Impr.) ; 71(2): 157-161, abr. 2019. ilus
Article in Spanish | LILACS | ID: biblio-1058249

ABSTRACT

INTRODUCCIÓN: Los tumores paratesticulares representan del 7%-10% de las masas intraescrotales. Los sarcomas abarcan el 90% de las lesiones malignas del cordón espermático y de éstas, aproximadamente, el 3%-7% son liposarcomas. CASO CLÍNICO: Presentamos el caso de un varón de 45 años, que consultó en urgencias por una masa inguinoescrotal derecha no reductible, diagnosticándose de hernia inguinal incarcerada. Se realizó cirugía urgente evidenciando una gran tumoración de aspecto lipomatoso, dependiente de cordón espermático. Se realizó orquiectomía y hernioplastía inguinal. La anatomía patológica, reveló un liposarcoma bien diferenciado de cordón espermático. Posteriormente, se realizó estudio de extensión, sin afectación a distancia y no precisó tratamiento adyuvante. Actualmente, tras dos años de seguimiento no ha presentado recidiva. DISCUSIÓN: Sólo alrededor de 200 casos han sido comunicados previamente en la literatura y sólo 61 de éstos se presentaron simulando una hernia inguinal incarcerada. Debido a la baja incidencia de esta patología es difícil de conocer la historia natural y llegar a conclusiones sobre los resultados del tratamiento, el cual hasta el momento sigue siendo la orquiectomía radical, con escisión amplia de los tejidos locales. El papel de la radio y quimioterapia aun es controvertido. CONCLUSIONES: Los sarcomas del cordón espermático son neoplasias raras con alta tasa de recurrencia local. Su manejo inicial es quirúrgico. Se requiere de un alto índice de sospecha clínica para el diagnóstico ya que las implicaciones oncológicas varían en función del tratamiento que, en ocasiones, es llevado a cabo por cirujanos generales al simular una hernia inguinal.


INTRODUCTION: Paratesticular tumors represent 7%-10% of intraescrotal masses. Sarcomas account for 90% of malignant lesions of the spermatic cord and of these approximately 3%-7% are liposarcomas. CLINICAL CASE: This is the case of a 45 year old male who consulted in the emergency department for a non-reducible right inguino-scrotal mass and was diagnosed with an incarcerated inguinal hernia. Emergency surgery was performed which revealed a large lipomatous tumor, originating from the spermatic cord. Orchiectomy and hernioplasty were performed. Histopathology revealed a well-differentiated liposarcoma of the spermatic cord. Later extension study was conducted, without distant affectation, and did not require adjuvant treatment. Today, after two years of monitoring has been no recurrence. DISCUSSION: Only about 200 cases have been previously reported in the literature and only 61 of these were presented mimicking an incarcerated inguinal hernia. Due to the low incidence of this disease it is difficult to know the natural history and draw conclusions on the results of treatment, which so far remains the radical orchiectomy with wide local excision of the tissue. The role of radiotherapy and chemotherapy is still controversial


Subject(s)
Humans , Male , Middle Aged , Testicular Neoplasms/surgery , Liposarcoma/surgery , Spermatic Cord , Spermatic Cord/pathology , Testicular Neoplasms/diagnosis , Orchiectomy/methods , Tomography, X-Ray Computed , Diagnosis, Differential , Hernia, Inguinal/surgery , Hernia, Inguinal/diagnosis , Liposarcoma/diagnosis
4.
Rev. cuba. med. gen. integr ; 34(2)abr.-jun. 2018. ilus
Article in Spanish | LILACS, CUMED | ID: biblio-1093438

ABSTRACT

Introducción: Conocemos como microlitiasis testicular a la afección en la cual se da la formación de calcificaciones en el interior del testículo. Su etiología es desconocida, y presenta mayor prevalencia en la edad adulta que en la pediátrica. Esta patología muestra su diagnóstico por medio de estudios imagenológicos. Caso clínico: Paciente de 17 años, el cual acude por dolor pélvico de un mes de evolución, y al cual se le diagnostica esta entidad tras los estudios complementarios. En el siguiente estudio se realiza una revisión bibliográfica de los aspectos relevantes de la patología y tratamiento, así como, la relación que existe entra la microlitiasis testicular y la neoplasia de testículo, infertilidad y patologías de base genética, tópicos de sumo interés para el médico general de atención en nivel primario de salud, considerando el manejo de control y prevención que debe aplicarse día a día en la consulta médica. Conclusiones: El conocimiento de las complicaciones que podrían presentarse en el paciente portador de microlitiasis testicular, obligan al médico a mostrar una actitud prudente ante esta patología, considerando el aspecto preventivo de la atención primaria de salud(AU)


Introducción: Conocemos como microlitiasis testicular a la afección en la cual se da la formación de calcificaciones en el interior del testículo. Su etiología es desconocida, y presenta mayor prevalencia en la edad adulta que en la pediátrica. Esta patología muestra su diagnóstico por medio de estudios imagenológicos.m Caso clínico: Paciente de 17 años, el cual acude por dolor pélvico de un mes de evolución, y al cual se le diagnostica esta entidad tras los estudios complementarios. En el siguiente estudio se realiza una revisión bibliográfica de los aspectos relevantes de la patología y tratamiento, así como, la relación que existe entra la microlitiasis testicular y la neoplasia de testículo, infertilidad y patologías de base genética, tópicos de sumo interés para el médico general de atención en nivel primario de salud, considerando el manejo de control y prevención que debe aplicarse día a día en la consulta médica. Conclusiones: El conocimiento de las complicaciones que podrían presentarse en el paciente portador de microlitiasis testicular, obligan al médico a mostrar una actitud prudente ante esta patología, considerando el aspecto preventivo de la atención primaria de salud(AU)


Subject(s)
Humans , Male , Adolescent , Primary Health Care , Testicular Neoplasms/complications , Testicular Neoplasms/diagnosis , Testicular Neoplasms/epidemiology , Ultrasonography/methods
6.
Rev. chil. pediatr ; 87(6): 494-499, Dec. 2016. ilus, tab
Article in Spanish | LILACS | ID: biblio-844571

ABSTRACT

Introducción: El síndrome H es una enfermedad genética extremadamente rara de compromiso multisistémico, el cual clínicamente puede ser reconocido de forma precoz, ofreciendo de manera oportuna un seguimiento, tratamiento específico y asesoramiento genético. Objetivo: Presentar un caso con características «típicas del síndrome H¼ para favorecer su identificación precoz. Caso clínico: Varón de 8 años de edad, evaluado por tumoraciones testiculares, lesiones dérmicas tipo hiperpigmentación con hipertricosis, retraso del lenguaje, talla baja, deformidades articulares, hipoacusia neurosensorial bilateral, anemia, hipergammaglobulinemia y alteraciones óseas. En los estudios histológicos de la piel y las masas testiculares se observó infiltración linfoplasmocitaria. El secuenciamiento del gen SLC29A3 detectó una mutación homocigota c.1087 C>T (p.Arg363Trp; rs387907067) concluyente con el síndrome H, la cual ha sido reportada previamente. Conclusiones: Este es el primer caso reportado en Latinoamérica del síndrome H, cuyas características descritas son parte del espectro clínico. El hallazgo clínico principal, que orienta al diagnóstico, es la hiperpigmentación acompañada de hipertricosis.


Introduction: H Syndrome is an extremely rare genetic disease, with a multisystemic character and which can be identified in early childhood, offering the opportunity of specific treatment and genetic counselling. Objective: To present a clinical case with "typical" characteristics of H Syndrome. Clinical case: The case is presented of an 8-year-old male patient who presented with testicular tumours and skin lesions characterised by hyperpigmentation with hypertrichosis, language delay, short stature, and joint deformities. He also presented with bilateral sensorineural hearing loss, anaemia, hypergammaglobulinaemia, and bone disorders. Histopathology studies of the skin and testicular masses reported lymphoplasmacytic infiltration. Sequencing analysis of gene SLC29A3 showed the homozygote mutation c.1087 C>T (p.Arg363Trp; rs387907067). Conclusions: These findings are consistent with H syndrome, and this is the first reported case in Latin America. The key to the diagnosis is the finding of hyperpigmentation with hypertrichosis.


Subject(s)
Humans , Male , Child , Testicular Neoplasms/genetics , Hyperpigmentation/genetics , Nucleoside Transport Proteins/genetics , Hypertrichosis/genetics , Syndrome , Testicular Neoplasms/diagnosis , Testicular Neoplasms/pathology , Body Height/genetics , Hyperpigmentation/diagnosis , Hyperpigmentation/pathology , Hearing Loss, Sensorineural/genetics , Hypertrichosis/diagnosis , Hypertrichosis/pathology , Language Development Disorders/genetics , Latin America , Mutation
7.
Int. braz. j. urol ; 42(1): 53-59, Jan.-Feb. 2016. tab, graf
Article in English | LILACS | ID: lil-777319

ABSTRACT

ABSTRACT Purpose The aim of the study was to investigate white blood cell counts and neutrophil to lymphocyte ratio (NLR) as markers of systemic inflammation in the diagnosis of localized testicular cancer as a malignancy with initially low volume. Materials and Methods Thirty-six patients with localized testicular cancer with a mean age of 34.22±14.89 years and 36 healthy controls with a mean age of 26.67±2.89 years were enrolled in the study. White blood cell counts and NLR were calculated from complete blood cell counts. Results White blood cell counts and NLR were statistically significantly higher in patients with testicular cancer compared with the control group (p<0.0001 for all). Conclusions Both white blood cell counts and NLR can be used as a simple test in the diagnosis of testicular cancer besides the well-known accurate serum tumor markers as AFP (alpha fetoprotein), hCG (human chorionic gonadotropin) and LDH (lactate dehydrogenase).


Subject(s)
Humans , Male , Adult , Testicular Neoplasms/diagnosis , Testicular Neoplasms/blood , Lymphocytes , Neoplasms, Germ Cell and Embryonal/diagnosis , Neoplasms, Germ Cell and Embryonal/blood , Neutrophils , Prognosis , Reference Values , Testicular Neoplasms/pathology , Varicocele/blood , Hemoglobins/analysis , Biomarkers, Tumor/blood , Case-Control Studies , Reproducibility of Results , Retrospective Studies , ROC Curve , Neoplasms, Germ Cell and Embryonal/pathology , Statistics, Nonparametric , Lymphocyte Count , Tumor Burden , Middle Aged
9.
Rev. Soc. Bras. Med. Trop ; 48(4): 501-503, July-Aug. 2015. ilus
Article in English | LILACS | ID: lil-755977

ABSTRACT

Abstract

Despite its infrequent occurrence, testicular schistosomiasis forming pseudo-tumors can be considered in the differential diagnosis of testicular tumors, especially in areas where the parasitic disease is endemic. In this report, we present a case of testicular schistosomiasis caused by Schistosoma mansoni and mimicking a testicular neoplasm. We describe the patterns of a testicular nodule on ultrasonography and magnetic resonance images in a 46-year-old man. The nodule was removed after a pre-operative diagnosis of a non-malignant lesion. Histology demonstrated granulomas with epithelioid macrophages and eosinophils around S. mansoni eggs within a fibrous tissue that formed a nodular structure.

.


Subject(s)
Animals , Humans , Male , Middle Aged , Schistosoma mansoni/isolation & purification , Schistosomiasis mansoni/diagnosis , Testicular Diseases/parasitology , Chronic Disease , Diagnosis, Differential , Testicular Diseases/diagnosis , Testicular Neoplasms/diagnosis
10.
Int. braz. j. urol ; 41(3): 588-590, May-June 2015. ilus
Article in English | LILACS | ID: lil-755886

ABSTRACT

ABSTRACTBackground:

Testicular calculus is an extremely rare case with unknown etiology and pathogenesis. To our knowledge, here we report the third case of testicular calculus. A 31-year-old man was admitted to our clinic with painful solid mass in left testis. After diagnostic work-up for a possible testicular tumour, he underwent inguinal orchiectomy and histopathologic examination showed a testicular calculus.

Case hypothesis:

Solid testicular lesions in young adults generally correspond to testicular cancer. Differential diagnosis should be done carefully.

Future implications:

In young adults with painful and solid testicular mass with hyperechogenic appearance on scrotal ultrasonography, testicular calculus must be kept in mind in differential diagnosis. Further reports on this topic may let us do more clear recommendations about the etiology and treatment of this rare disease.

.


Subject(s)
Humans , Male , Adult , Testicular Diseases/pathology , Calculi/pathology , Rare Diseases/pathology , Testicular Diseases/surgery , Testicular Neoplasms/diagnosis , Calculi/surgery , Orchiectomy , Rare Diseases/surgery , Diagnosis, Differential
11.
Rev. AMRIGS ; 59(1): 28-29, jan.-mar. 2015. ilus
Article in Portuguese | LILACS | ID: biblio-836832

ABSTRACT

Mesoteliomas são tumores oriundos das células mesoteliais da pleura, peritônio, pericárdio ou túnica vaginal, sendo a exposição prolongada ao asbesto o principal fator de risco. Neoplasias mesoteliais benignas da região paratesticular são raras. Relata-se um caso de Mesotelioma de Túnica Vaginal associado à hidrocele, destacando a utilidade da ecografia na avaliação das massas escrotais (AU)


Mesotheliomas are tumors originating from the mesothelial cells of the pleura, peritoneum, pericardium or tunica vaginalis, with prolonged exposure to asbestos the main risk factor. Benign mesothelial neoplasms of the paratesticular region are rare. Here we report a case of tunica vaginalis mesothelioma associated with hydrocele, highlighting the usefulness of ultrasound in the evaluation of scrotal masses (AU)


Subject(s)
Humans , Male , Adult , Testicular Neoplasms/pathology , Mesothelioma/pathology , Testicular Neoplasms/surgery , Testicular Neoplasms/diagnosis , Mesothelioma/surgery , Mesothelioma/diagnosis
12.
Korean Journal of Urology ; : 318-323, 2015.
Article in English | WPRIM | ID: wpr-34595

ABSTRACT

PURPOSE: Testicular microlithiasis (TM) is a relatively rare clinical entity of controversial significance characterized by the existence of hydroxyapatite microliths located in the seminiferous tubules. The aim of this study was to observe the natural course of changes in the calcific density of pediatric TM. MATERIALS AND METHODS: We included a total of 23 TM patients undergoing scrotal ultrasound (US) on at least two occasions from July 1997 to August 2014. We retrospectively analyzed the patient characteristics, clinical manifestations, specific pathological features, and clinical outcomes. We measured the calcified area and compared the calcific density between the initial and final USs. RESULTS: The mean age at diagnosis was 11.3+/-4.6 years, and the follow-up period was 79.1+/-38.8 months (range, 25.4-152.9 months). During the follow-up period, no patients developed testicular cancer. Calcific density on US was increased in the last versus the initial US, but not to a statistically significant degree (3.74%+/-6.0% vs. 3.06%+/-4.38%, respectively, p=0.147). When we defined groups with increased and decreased calcification, we found that diffuse TM was categorized into the increased group to a greater degree than focal TM (10/20 vs. 4/23, respectively, p=0.049). In addition, five of eight cases of cryptorchidism (including two cases of bilateral cryptorchidism) were categorized in the increased calcification group. CONCLUSIONS: Diffuse TM and cryptorchidism tend to increase calcific density. Close observation is therefore recommended for cases of TM combined with cryptorchidism and cases of diffuse TM.


Subject(s)
Adolescent , Calcification, Physiologic , Calculi/complications , Child , Cryptorchidism/diagnosis , Densitometry/methods , Follow-Up Studies , Gonadoblastoma/diagnosis , Humans , Male , Republic of Korea , Scrotum/diagnostic imaging , Seminiferous Tubules/pathology , Testicular Diseases/complications , Testicular Neoplasms/diagnosis
13.
Korean Journal of Urology ; : 515-518, 2015.
Article in English | WPRIM | ID: wpr-171068

ABSTRACT

PURPOSE: It is well known that testicular germ cell tumors arise with increased frequency in patients with cryptorchidism. In addition, intratubular germ cell neoplasia (ITGCN) is a precursor lesion to testicular germ cell tumor. Approximately 50% of patients with ITGCN will develop an invasive of testicular germ cell tumors within 5 years. Therefore, we evaluated that the incidence of ITGCN in postpubertal cryptorchidism. MATERIALS AND METHODS: Between January 2002 and August 2012, orchiectomy specimens from 31 postpubertalpatients (aged 12 or over) with cryptorchid testis were reviewed. The specimens were evaluated for ITGCN using immunohistochemical stains of placental-like alkaline phosphatase and Oct 3/4 with routine hematoxylin-eosin stain. Additionally, the degree of spermatogenesis was assessed using the Johnsen score. RESULTS: Mean age was 34 years (range, 17 to 74 years) at surgery. All patients were diagnosed as unilateral cryptorchidism. One patient (3.2%) of 20-year-old had ITGCN in surgical specimen with all positive markers. Histological assessment of spermatogenesis showed that mean Johnsen score was 3.42 (range, 1 to 9). Majority of patients (27 of 31) presented impaired spermatogenesis with low Johnsen score lesser than 5. CONCLUSIONS: Considering the risk of malignancy and low spermatogenesis, we should perform immunohistochemical stains and discuss preventative orchiectomy for the postpubertal cryptorchidism.


Subject(s)
Adolescent , Adult , Aged , Alkaline Phosphatase/metabolism , Biomarkers, Tumor/metabolism , Carcinoma in Situ/diagnosis , Cryptorchidism/complications , Disease Progression , Humans , Infertility, Male/etiology , Isoenzymes/metabolism , Male , Middle Aged , Neoplasms, Germ Cell and Embryonal/diagnosis , Orchiectomy , Puberty , Retrospective Studies , Spermatogenesis , Testicular Neoplasms/diagnosis , Young Adult
14.
Article in English | IMSEAR | ID: sea-154433

ABSTRACT

Embryonal cell carcinoma affects young males in the prime of their life with majority of tumours already having metastasised at the time of diagnosis. Subcutaneous metastasis from embryonal carcinoma is rare and is associated with widespread disease and poor prognosis. We report a case of 22-year-old male who presented with haemoptysis and skin nodules. Fine needle aspiration cytology of skin nodules and the lung lesion led to the diognosis of testicular embryonal cell carcinoma.


Subject(s)
Bone Neoplasms/secondary , Carcinoma, Embryonal/diagnosis , Carcinoma, Embryonal/pathology , Hemoptysis/etiology , Humans , Lung Neoplasms/secondary , Male , Testicular Neoplasms/diagnosis , Testicular Neoplasms/pathology , Young Adult
15.
Korean Journal of Urology ; : 789-796, 2014.
Article in English | WPRIM | ID: wpr-219574

ABSTRACT

Prepubertal testicular tumors are rare compared with postpubertal testicular tumors. The incidence of prepubertal testicular tumors peaks at 2 years of age, tapers off after 4 years of age, and then begins to rise again at puberty. Prepubertal and postpubertal testicular tumors show many differences, including the typical tumor histology, molecular biological differences, and the malignant potential of tumors at different ages. Pediatric testicular tumors are classified as benign or malignant on the basis of their clinical behavior and histologically are divided into germ cell and gonadal stromal (nongerm cell) tumors. Many histological and biological studies have further confirmed the distinct nature of prepubertal and postpubertal testicular tumors. These differences have led to various management strategies for prepubertal and postpubertal tumors. Because overall about 75% of prepubertal testicular tumors are benign, a testis-sparing approach is becoming more common in children. Orchiectomy and observation with very selective use of chemotherapy has become the standard approach when a malignant tumor is identified. Retroperitoneal lymph node dissection and radiation therapy play very limited roles.


Subject(s)
Age Distribution , Child , Humans , Incidence , Male , Prognosis , Republic of Korea/epidemiology , Testicular Neoplasms/diagnosis
16.
Article in English | WPRIM | ID: wpr-70740

ABSTRACT

Sparganosis is a parasitic infestation of human by plerocercoid larvae. Sparganum is usually reported to be found in the subcutaneous tissues as well as other organs, including scrotum. However, testicular sparganosis is extremely rare, because of strong capsule of tunica albuginea. An urban-living 54-yr-old Korean man presented with left scrotal pain for 6 yr. Both testes look normal physically. Ultrasonography revealed poorly defined, heterogeneous mass with increased echogenicity in the left testis. This case was misdiagnosed as testicular tumor and underwent orchiectomy, but was diagnosed as testicular sparganosis by histopathology. Sparganosis should be included for differential diagnosis of testis tumor in countries where sparganosis is prevalent.


Subject(s)
Diagnosis, Differential , Diagnostic Errors , Humans , Male , Middle Aged , Orchiectomy , Sparganosis/diagnosis , Testicular Neoplasms/diagnosis , Testis/pathology
18.
Urology Annals. 2014; 6 (2): 173-175
in English | IMEMR | ID: emr-157499

ABSTRACT

Testicular neuroendocrine tumor is rare. It accounts for less than 1% of all testicular neoplasms. More than 60 cases have been published in the literature. A 27-year-old man presented with left testicular mass and underwent radical orchidectomy. Histological examination showed neuroendocrine tumor, confirmed by immunohistochemistry and electron microscopy. The patient showed no evidence of metastasis over 1-year follow-up post-orchidectomy in spite of extensive tumor necrosis


Subject(s)
Humans , Male , Testicular Neoplasms/diagnosis , Immunohistochemistry , Neoplasm Metastasis , Orchiectomy , Microscopy, Electron
19.
Rev. paul. pediatr ; 31(4): 554-558, dez. 2013. tab, graf
Article in English | LILACS | ID: lil-698046

ABSTRACT

OBJECTIVE: To discuss the relationship between testicular microlithiasis and testis tumors in children and to consider the chances of testis preserving surgery in specific cases. CASE DESCRIPTION: Pre-adolescent presenting testicular microlithiasis and a larger left testis, corresponding to a cystic testicular tumor. The tumor was excised, with ipsilateral testis preservation. Histology diagnosed a testis dermoid tumor. COMMENTS: The relationship between testis tumors and testicular microlithiasis is ill defined in children. Pediatric urologists need to develop specific follow-up protocols for pre-pubertal children. .


OBJETIVO: Discutir las implicaciones de la microlitíasis testicular en el niño con relación al riesgo oncológico implicado y la posibilidad de cirugía de preservación testicular en casos elegidos. DESCRIPCIÓN DEL CASO: Pre-adolescente presentando aumento microlitíasis testicular y aumento del testículo izquierdo, con lesión tumoral quística. La lesión fue resecada, con preservación del testículo y diagnóstico histológico de tumor dermatoide testicular. COMENTARIOS: La relación entre tumores de testículo y microlitíasis testicular es mal definida en niños y hay la necesidad de desarrollar protocolos de seguimiento específicos para esa franja de edad. .


OBJETIVO: Discutir as implicações da microlitíase testicular na criança com relação ao risco oncológico envolvido e a possibilidade de cirurgia de preservação testicular em casos escolhidos. DESCRIÇÃO DO CASO: Pré-adolescente apresentava microlitíase testicular e aumento do testículo esquerdo, correspondendo a tumor testicular cístico. Ressecou-se o tumor, com preservação do testículo. O diagnóstico histológico foi de tumor dermoide testicular. COMENTÁRIOS: A relação entre tumores de testículo e microlitíase testicular é mal definida em crianças e há a necessidade de desenvolver protocolos de seguimento específicos para essa faixa etária. .


Subject(s)
Child , Humans , Male , Calculi/complications , Dermoid Cyst/complications , Testicular Diseases/complications , Testicular Neoplasms/complications , Calculi/diagnosis , Calculi/surgery , Dermoid Cyst/diagnosis , Dermoid Cyst/surgery , Testicular Diseases/diagnosis , Testicular Diseases/surgery , Testicular Neoplasms/diagnosis , Testicular Neoplasms/surgery
20.
West Indian med. j ; 62(6): 557-560, July 2013. ilus, tab
Article in English | LILACS | ID: biblio-1045698

ABSTRACT

Brucellosis is a zoonosis caused by gram negative coccobacilli and it is an endemic infectious disease in Turkey. Infection is usually acquired as a result of direct contact with infected animals or by consuming milk or cheese freshly made from them. There exists a wide spectrum of clinical signs and symptoms in brucellosis. Many systems including musculoskeletal, gastrointestinal, cardiovascular and genitourinary may be involved in brucellosis. The genitourinary system is affected in 2% to 20% of the cases with brucellosis. The most common forms of brucellosis are epididymo-orchitis, testicular abscess and atrophy. The serum agglutination test to detect the presence of antibodies is a reliable test in patients with urogenital symptoms. Long-term and combined antibacterial therapy have been found to be effective in brucellosis. We present two cases undergoing orchiectomy because of testicular mass before the diagnosis ofbrucellosis was made.


La brucelosis es una zoonosis causada por cocobacilos gram negativos, y es una enfermedad infecciosa endémica en Turquía. La infección generalmente se adquiere como resultado del contacto directo con animales infectados o por consumo de leche o queso recién producidos a partir de ellos. Existe un amplio espectro de signos y síntomas clínicos de la brucelosis. Muchos sistemas, incluyendo los sistemas musculoesquelético, cardiovascular, gastrointestinal y génitourinario, pueden estar implicados en la brucelosis. El sistema génitourinario se ve afectado en 2% a 20% de los casos con brucelosis. Las formas más comunes de brucelosis son la epidídimo-orquitis, el absceso testicular, y la atrofia. La prueba de aglutinación de suero para detectar la presencia de anticuerpos es una prueba confiable en pacientes con síntomas urogenitales. Se ha hallado que la terapia antibacteriana combinada y a largo plazo son eficaces en la brucelosis. Presentamos dos casos sometidos a orquiectomía debido a una masa testicular antes de que se realizara el diagnóstico de brucelosis.


Subject(s)
Humans , Male , Young Adult , Orchitis/diagnosis , Testicular Neoplasms/diagnosis , Brucellosis/diagnosis , Orchiectomy , Orchitis/surgery , Brucellosis/surgery , Diagnosis, Differential
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