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1.
Diagn. tratamento ; 26(3): 93-6, jul-set. 2021. Este editorial foi previamente publicado em inglês no periódico São Paulo Medical Journal, volume 139, edição número 4, julho e agosto de 2021 (https://doi.org/10.1590/1516-3180.2021.139420052021)
Article in Portuguese | LILACS | ID: biblio-1291192
2.
Rev. med. Risaralda ; 27(1): 28-34, ene.-jun. 2021. tab, graf
Article in Spanish | LILACS, COLNAL | ID: biblio-1280490

ABSTRACT

Resumen Introducción: La Enfermedad de Chagas también conocida como Tripanosomiasis americana es un problema de salud pública. Se calcula que en el mundo hay entre 6 y 7 millones de personas infectadas por Trypanosoma cruzi, la mayoría de ellas en América Latina. Objetivo: Identificar la prevalencia de infección por Trypanosoma cruzi en donantes de un banco de sangre del departamento de Boyacá 2016-2018. Materiales y métodos: Estudio descriptivo retrospectivo realizado en 25.920 donantes de sangre del departamento de Boyacá. La fuente de información fue secundaria. Se determinó la prevalencia de la infección por Trypanosoma cruzi y se compararon según sexo, grupo etario y tipo de donante a través de análisis de frecuencias. Resultados: Se evaluaron 9187 donantes durante el año 2016; 8517 en el 2017 y 8216 en el 2018, de los cuales 56,1% eran de sexo femenino y 43,9% masculino. La prevalencia de la infección por Trypanosoma cruzi fue 0,17 % en la tamización y 0,08 % con las pruebas confirmatorias de las cuales el 70,0% eran mujeres, el 85,0% donantes voluntarios por primera vez, el rango de edad en el que se presentó mayor prevalencia de este marcador serológico fue de 41 a 50 y de 51 a 65 años con un 35,0% cada uno . La prevalencia de la infección de Chagas presentó asociación estadísticamente significativa con la edad (p < 0,05). Conclusiones: Los bancos de sangre resultan ser una de las fuentes de información disponibles para monitorear el comportamiento de la enfermedad de Chagas y evaluar la toma de decisiones en salud pública, teniendo en cuenta que la enfermedad se caracteriza de manera asintomática y sin compromiso clínico en la mayoría de los casos.


Abstract Introduction: Chagas Disease, also known as American Trypanosomiasis, is a public health problem. It is estimated that in the world there are between 6 and 7 million people infected with Trypanosoma cruzi, most of them in Latin America. Objectives: To identify the prevalence of Trypanosoma cruzi infection in donors from a blood bank in the department of Boyacá 2016-2018. Materials and methods: Retrospective-descriptive study carried out in 25,920 blood donors from the department of Boyacá (Colombia). The source of information was secondary. The prevalence of Trypanosoma cruzi infection was determined and compared according to sex, age group and type of donor through frequency analysis. Results: 9187 donors were evaluated during 2016; 8,517 in 2017 and 8,216 in 2018, of which 56.1% were female and 43.9% male. The prevalence of Trypanosoma cruzi infection was 0.17% in screening and 0.08% with confirmatory tests of which 70.0% were women, 85.0% first-time volunteer donors, the range of The age at which the highest prevalence of this serological marker was found was 41 to 50 and 51 to 65 years with 35.0% each. The prevalence of Chagas infection showed a statistically significant association with age (p <0.05). Conclusions: Blood banks turn out to be one of the sources of information available to monitor the behavior of Chagas disease and evaluate decision-making in public health, taking into account the characteristics of the disease in which the majority of cases they are asymptomatic and without clinical compromise.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Trypanosoma cruzi , Blood Banks , Blood Donors , Chagas Disease , Tissue Donors , Volunteers , Blood , Mass Screening , Prevalence , Infections
3.
Rev. cuba. hematol. inmunol. hemoter ; 37(2): e1261, 2021. tab
Article in Spanish | LILACS, CUMED | ID: biblio-1289430

ABSTRACT

Introducción: La búsqueda de alternativas para disminuir el tiempo de cicatrización y de hospitalización constituye uno de los aspectos fundamentales de la investigación actual. Los factores de crecimiento plaquetarios son capaces de potenciar la cicatrización. Objetivo: Determinar los beneficios de la aplicación del lisado de plaquetas homólogo sobre la zona donante del injerto autólogo de piel. Método: Se realizó un estudio longitudinal prospectivo en 20 pacientes tratados en el Hospital Hermanos Ameijeiras entre agosto de 2016 y mayo de 2019, que requirieron de injerto autólogo de piel en las zonas cruentas. Se realizaron dos tomas de injerto en el mismo paciente y región anatómica; una fue tratada con lisado plaquetario (zona de intervención) y otra con tratamiento convencional (zona control). La selección de pacientes fue intencional. Para estudiar las variables cualitativas se utilizaron números absolutos y proporciones y en las cuantitativas medidas de tendencia central y dispersión. Para la comparación de los resultados se aplicó la prueba de Friedman con un nivel de significación p ≤ 0,05. Resultados: La quemadura fue la principal causa de zona cruenta (75 por ciento), el grupo de edad más afectado fue el de mayores de 55 años. El porcentaje de cicatrización fue mayor en el grupo de intervención, con un tiempo de epitelización significativamente menor (p < 0,01), y el dolor en la zona intervenida fue menor. No hubo complicaciones. Conclusiones: Los beneficios encontrados en la zona intervenida con lisado plaquetario fueron significativos con una cicatrización más rápida y menor dolor(AU)


Introduction: The search for treatment alternatives that allow reducing wound healing and hospitalization time are fundamental aspects in research nowadays. Platelet growth factors are capable of enhancing wound healing. Objective: Determine the benefits of applying homologous platelet lysate on the donor area of autologous skin graft. Methods: A prospective longitudinal-section study was conducted in 20 patients with bloody areas that required autologous skin graft at the Hospital Hermanos Ameijeiras between August 2016 and May 2019. Two graft intakes were made in the same patient and anatomical region, one of them treated with platelet lysate (intervention zone) and one with conventional treatment (control zone). Patients selection was intentional. Absolute numbers and proportions were used to study the qualitative variables, and measures of central tendency and dispersion were used in the quantitative variables. To compare de results, the Friedman test was applied, setting a level of significance p < 0,05. Results: The main cause of bloody area was burns (75 percent), the most affected age group was those over 55 years, the healing percentage was greater in the intervention group with a statistically significant shorter epithelization time (p < 0,01) and there was less pain in the intervention zone. There were no complications. Conclusions: The benefits found in the intervened area with platelet lysate were significant with faster healing and less pain(AU)


Subject(s)
Humans , Tissue Donors , Wound Healing , Blood Platelets
4.
Rev. cuba. invest. bioméd ; 40(1): e813, ene.-mar. 2021. graf
Article in Spanish | LILACS, CUMED | ID: biblio-1289455

ABSTRACT

Introducción: La encía queratinizada es un componente importante del complejo mucogingival. Su ausencia puede deberse a recesiones gingivales, traumas, caries radicular, entre otras. La técnica de injerto gingival libre es considerada el estándar de oro, por ser una técnica óptima para aumentar la extensión del vestíbulo y el ancho del tejido queratinizado por sus altas tasas de éxito y predictibilidad clínica. Objetivo: El propósito de este caso clínico fue evaluar el uso de una modificación de la técnica del injerto gingival libre. Presentación de caso: El caso clínico incluyó aumento de la profundidad del vestíbulo y de la encía queratinizada en ambas zonas del sector anteroinferior, para lo cual se utilizaron las dos hemiarcadas del paladar como la zona dadora del injerto (doble injerto). El caso utilizó un doble injerto gingival libre como técnica novedosa para el aumento gingival. Después de dos meses de cicatrización, se observó reducción de la recesión gingival y un aumento notorio del ancho de la encía queratinizada. Conclusiones: La técnica modificada de doble injerto gingival libre, es una buena alternativa para aumentar el grosor de la encía queratinizada en el sector anteroinferior, además de reducir el tiempo posoperatorio y generar una cicatrización uniforme a nivel de la línea mucogingival(AU)


Introduction: Keratinized gingiva is an important component of the mucogingival complex. Its absence may be due to gingival recessions, trauma, root caries, among others. The free gingival graft technique is considered the gold standard, as it is an optimal technique to increase the extension of the vestibule and the width of the keratinized tissue due to its high success rates and clinical predictability. Objective: The purpose of this clinical case was to evaluate the use of a modification of the free gingival graft technique. Case report: The clinical case included an increase in the depth of the vestibule as well as the keratinized gingiva in both areas of the anteroinferior sector, for which the two hemiarchates of the palate were used as the graft donor area (double graft). The case used a free double gingival graft as a novel technique for gingival augmentation. After two months of healing, a reduction in the gingival recession was observed, as well as a noticeable increase in the width of the keratinized gingiva. Conclusions: The modified free double gingival graft technique is a good alternative to increase the thickness of the keratinized gingiva in the anteroinferior sector, in addition to reducing the post-operative time and generating uniform healing at the level of the mucogingival line(AU)


Subject(s)
Humans , Tissue Donors , Wounds and Injuries , Operative Time , Gingival Recession , Herpes Zoster
6.
Nursing (Säo Paulo) ; 24(272): 5128-5147, jan.2021.
Article in Portuguese | LILACS, BDENF | ID: biblio-1148453

ABSTRACT

OBJETIVO: Conhecer os cuidados de enfermagem dispensadas ao potencial doador de órgãos em morte encefálica. MÉTODO: Revisão integrativa que se dividiu em seis etapas. Os critérios de inclusão foram os artigos disponíveis completos e gratuitos, em qualquer idioma visto a grande escassez de estudos na área, publicados entre os anos de 2010 a 2016. RESULTADOS: Foram encontrados 179 artigos dos quais 17 cumpriram aos critérios estabelecidos e foram incluídos na presente revisão. O conhecimento é essencial para a realização das condutas normalmente realizadas. A abordagem familiar dos potenciais doadores também faz parte das condutas de enfermagem, visto ser uma abordagem multiprofissional. Esse ponto é um dos mais críticos do processo de doação, visto o grande obstáculo interposto pelos familiares. CONCLUSÃO: É de grande importância que o profissional de enfermagem tenha sistematizada as ações que adotará frente a um caso de morte encefálica, principalmente relacionado a conduta com familiares.(AU)


OBJETIVO: Conhecer os cuidados de enfermagem dispensadas ao potencial doador de órgãos em morte encefálica. MÉTODO: Revisão integrativa que se dividiu em seis etapas. Os critérios de inclusão foram os artigos disponíveis completos e gratuitos, em qualquer idioma visto a grande escassez de estudos na área, publicados entre os anos de 2010 a 2016. RESULTADOS: Foram encontrados 179 artigos dos quais 17 cumpriram aos critérios estabelecidos e foram incluídos na presente revisão. O conhecimento é essencial para a realização das condutas normalmente realizadas. A abordagem familiar dos potenciais doadores também faz parte das condutas de enfermagem, visto ser uma abordagem multiprofissional. Esse ponto é um dos mais críticos do processo de doação, visto o grande obstáculo interposto pelos familiares. CONCLUSÃO: É de grande importância que o profissional de enfermagem tenha sistematizada as ações que adotará frente a um caso de morte encefálica, principalmente relacionado a conduta com familiares.(AU)


OBJETIVO: Conocer la atención de enfermería proporcionada al potencial donante de órganos en la muerte cerebral. METODO: Revisión integrativa que se dividió en seis etapas. Los criterios de inclusión fueron los artículos disponibles completos y gratuitos, en cualquier idioma visto por la gran escasez de estudios en la zona, publicados entre los años 2010 y 2016. RESULTADOS: Encontramos 179 artículos, 17 de los cuales cumplieron con los criterios establecidos y fueron incluidos en esta revisión. El conocimiento es esencial para realizar las conductas que normalmente se realizan. El enfoque familiar de los donantes potenciales también forma parte de las conductas de enfermería, ya que es un enfoque multiprofesional. Este punto es uno de los más críticos del proceso de donación, dado el gran obstáculo que traen los miembros de la familia. CONCLUSION: Es de gran importancia que el profesional de enfermería haya sistematizado las acciones que adoptará ante un caso de muerte cerebral, principalmente relacionadas con la conducta con los miembros de la familia.(AU)


Subject(s)
Humans , Tissue Donors , Tissue and Organ Procurement , Brain Death , Nursing Care , Advance Care Planning
7.
Epidemiol. serv. saúde ; 30(1): e2020754, 2021. tab, graf
Article in English, Portuguese | LILACS, ColecionaSUS, SES-SP | ID: biblio-1142940

ABSTRACT

Objetivo Descrever as doações e os transplantes de órgãos no Ceará, Brasil, após a declaração da pandemia da COVID-19. Métodos Estudo descritivo, com dados da Associação Brasileira de Transplantes de Órgãos. O número de doadores e transplantes do período de abril a junho de 2020 foi comparado ao mesmo período de 2019 e ao primeiro trimestre de 2020. Resultados No primeiro semestre de 2020, o estado registrou 72 doadores efetivos. Destes, 17 (23,6%) no segundo trimestre. Dos 352 transplantes do primeiro semestre de 2020, 37 (10,7%) foram realizados no segundo trimestre. Em comparação ao período de abril a junho de 2019, houve redução de 67,9% e 89,3% no número de doadores e transplantes, respectivamente, no mesmo período de 2020. Conclusão Os números de doadores e transplantes do Ceará apresentaram importante declínio nos três meses seguintes ao decreto da pandemia da COVID-19, especialmente os das modalidades de rim, coração e córneas.


Objetivo Describir las donaciones y trasplantes de órganos en Ceará, Brasil, después de la declaración de la pandemia COVID-19. Métodos estudio descriptivo con datos de la Asociación Brasileña de Trasplantes de Órganos. Se comparó el número de donantes y trasplantes de abril a junio de 2020 con el mismo período de 2019 y el primer trimestre de 2020. Resultados El primer semestre de 2020, Ceará registró 72 donantes efectivos. De estos, 17 (23,6%) en el segundo trimestre. De 352 trasplantes realizados en el primer semestre de 2020, 37 (10.7%) fueron realizados en el segundo trimestre. En comparación al período de abril a junio de 2019, hubo reducción de 67,9% y 89,3% en el número de donantes y trasplantes, respectivamente, en el mismo período de 2020. Conclusión El número de donantes y trasplantes en Ceará mostró importante disminución en los tres meses siguientes al decreto pandémico COVID-19, especialmente las modalidades renal, cardíaca y córneas.


Objective To describe organ donations and transplants in Ceará state, Brazil, following the declaration of the COVID-19 pandemic. Methods This was a descriptive study using data from the Brazilian Organ Transplantation Association. The number of donors and transplants from April to June 2020 was compared to the same period in 2019 and to the first quarter of 2020. Results In the first half of 2020, the state registered 72 effective donors, just 17 (23.6%) of whom related to the second quarter. Of the 352 transplants in the first half of 2020, 37 (10.7%) were performed in the second quarter. Compared with the period from April to June 2019, there was a reduction of 67.9% and 89.3% in the number of donors and transplants, respectively, in the same period of 2020. Conclusion The number of donors and transplants in Ceará showed an important fall in the three months following the declaration of the COVID-19 pandemic, especially for kidney, heart and cornea transplants.


Subject(s)
Humans , Tissue Donors/statistics & numerical data , Tissue and Organ Procurement/statistics & numerical data , Organ Transplantation/trends , Organ Transplantation/statistics & numerical data , Brazil , Coronavirus Infections , Pandemics , Health Services Research/statistics & numerical data
8.
Medicina (B.Aires) ; 80(6): 611-621, dic. 2020. graf
Article in English | LILACS | ID: biblio-1250283

ABSTRACT

Abstract Infections are frequent complications of kidney transplants. We aimed at determining the frequency and type of infections that occur in renal transplant recipients during the early (0-1 month), intermediate (1-6 months) and late (6-12 months) post-transplant period and analyzing the risk factors for infection. To this aim, we conducted a retrospective cohort study on 1-year post-transplant follow-up in two third-level university hospitals in Cordoba city. All consecutive recipients of renal transplants performed between 2009 and 2015 were included, except those with multiple solid organ transplantation and pediatric patients. We included 375 recipients, of which 235 (62.7%) had at least one episode of infection during follow-up. There were 504 episodes of infection, of which 131 (26%) occurred in the early, 272 (53.9%) in the intermediate, and 101 (20.1%) in the late post-transplant period. The most frequent infections in all periods were caused by bacteria (mainly urinary tract infections), and the most frequent viral infection was caused by Cytomegalovirus (mainly in the second and third period). In the multivariate analysis, infection risk factors were: age > 60 years (adjusted odds ratio [aOR] = 1.92; 95% CI = 1.05-3.49), organ transplantation from deceased donor (aOR = 8.19; 95% CI = 2.32-28.9), use of pigtail catheter for urinary tract drainage (aOR = 4.06; 95% CI = 1.27-12.9), and number of days in hospital after transplant (aOR = 1.05; 95% CI = 1.01-1.11). In conclusion, infections in renal transplant recipients represent a very frequent health problem in our hospitals. Understanding the local epidemiology of infection and the potential risk factors for infection acquires utmost importance.


Resumen Las infecciones son complicaciones frecuentes de los trasplantes renales. Los objetivos del estudio fueron determinar la frecuencia y el tipo de infecciones que ocurren en el período post-trasplante temprano (0-1 mes), intermedio (1-6 meses) y tardío (6-12 meses) en nuestro medio y analizar los factores de riesgo de infección. Se realizó un estudio de cohorte retrospectivo que incluyó todos los pacientes con trasplantes renales realizados entre 2009 y 2015 en dos hospitales universitarios de tercer nivel de la ciudad de Córdoba, excluidos los receptores de trasplante simultáneo de múltiples órganos sólidos y los menores de 18 años. Fueron incluidos 375 pacientes, de los cuales 235 (62.7%) tuvieron al menos un episodio de infección. Hubo 504 episodios de infección: 131 (26%) ocurrieron en el período temprano, 272 (53.9%) en el intermedio y 101 (20.1%) en el tardío. La mayoría de las infecciones fueron de origen bacteriano (principalmente del tracto urinario). La mayoría de las infecciones virales ocurrieron en el segundo y el tercer período y Citomegalovirus fue el responsable más frecuente. En el análisis multivariado, los factores de riesgo de infección post-transplante renal fueron: edad > 60 años (odds ratio ajustado [aOR] 1.92; IC95% 1.05-3.49), donante cadavérico (aOR 8.19; IC95% 2.32-28.9), uso de catéter pigtail (aOR 4.06; IC95% 1.27-12.9) y número de días internado postrasplante (aOR 1.05; IC95% 1.01-1.11). En conclusión, confirmamos que las infecciones en pacientes con trasplante renal son muy frecuentes en nuestro medio, por lo cual es importante conocer la epidemiología local y los factores de riesgo.


Subject(s)
Humans , Child , Urinary Tract Infections , Kidney Transplantation/adverse effects , Tissue Donors , Retrospective Studies , Risk Factors
9.
Cambios rev. méd ; 19(2): 6-11, 2020-12-29. ^eVIDEO: https://youtu.be/kIDnpec0mnkilus.
Article in Spanish | LILACS | ID: biblio-1179137

ABSTRACT

INTRODUCCIÓN. El primer trasplante hepático en el mundo se realizó en Estados Unidos en 1963 por Thomas Starzl, hasta la década de los 90 la supervivencia al año fue de 73% y a los 5 años de 64%, según diferentes series que abarcaron más de 1 000 trasplantes realizados hasta 1989. El Ecuador requiere de estas estadísticas. El Hospital de Especialidades Carlos Andrade Marín inició la actividad del programa en mayo del 2016. OBJETIVO. Conocer la supervivencia global de los pacientes sometidos a trasplante hepático. MATERIALES Y MÉTODOS. Estudio observacional, descriptivo, con una población igual a la muestra de 62 datos de Historias Clínicas del Programa de Trasplante Hepático en la Unidad Técnica de Trasplante del Hospital de Especialidades Carlos Andrade Marín en el período mayo 2016 a diciembre 2019. Criterios de inclusión: pacientes so-metidos a trasplante hepático, con seguimiento durante 43 meses. La información se obtuvo de la base de datos del sistema AS400; se analizaron en el programa estadístico International Business Machines Statistical Package for the Social Sciences, versión 23.0. RESULTADOS. La supervi-vencia global a los 12 meses fue 72% (17; 62) y a los 43 meses fue 69% (19; 62). DISCUSIÓN. Se evidenció similares resultados descritos de supervivencia en centros con actividad en periodos cortos, menor a 5 años. CONCLUSIÓN. Se pudo conocer la supervivencia global de los pacientes trasplantados del hospital, cuya expectativa motiva a potenciar el programa para mejorar la calidad de vida de los pacientes candidatos a trasplante.


INTRODUCTION. The first liver transplant in the world was performed in the United States in 1963 by Thomas Starzl, until the 90s the survival at one year was 73% and at 5 years it was 64%, accor-ding to different series that included more than 1 000 transplants carried out until 1989. Ecuador re-quires these statistics. The Carlos Andrade Marín Specialty Hospital began program activity in May 2016. OBJECTIVE. To know the overall survival of patients undergoing liver transplantation. MATE-RIALS AND METHODS. Observational, descriptive study, with a population equal to the sample of 62 data from the Medical Records of the Liver Transplant Program in the Technical Transplant Unit of the Carlos Andrade Marín Specialty Hospital in the period May 2016 to December 2019. Inclusion criteria: patients submitted to liver transplantation, with follow-up for 43 months. The information was obtained from the AS400 system database; were analyzed in the statistical program Internatio-nal Business Machines Statistical Package for the Social Sciences, version 23.0. RESULTS. Ove-rall survival at 12 months was 72% (17; 62) and at 43 months it was 69% (19; 62). DISCUSSION. Similar survival results described were evidenced in centers with activity in short periods, less than 5 years. CONCLUSION. It was possible to know the overall survival of the transplanted patients at the hospital, whose expectation motivates us to promote the program to improve the quality of life of the transplant candidates.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Transplantation , Survival Analysis , Liver Transplantation , Hemochromatosis , Liver , Liver Cirrhosis , Quality of Life , Survival , Tissue Donors , Medical Records , Aftercare , Survivorship
10.
Rev. bras. ortop ; 55(6): 736-741, Nov.-Dec. 2020. tab, graf
Article in English | LILACS | ID: biblio-1156197

ABSTRACT

Abstract Objective To describe and demonstrate the outcomes of the modified Monteiro (1991) technique for lower limb reconstruction with a fasciocutaneous flap of the distal pedicle in a series of 15 cases. Method We present the technique and outcomes from a series of 15 cases of the modified technique using a fasciocutaneous flap of the distal pedicle to repair the lower third of the leg and the foot. Results Outcomes were satisfactory since these flaps provided good cutaneous and subcutaneous tissue coverage in cases with bone exposure and skin loss. The donor area was closed 3 days after surgery with a partial skin graft to provide better graft viability. Conclusion The fasciocutaneous flap of the distal pedicle proved to be a good option for reconstruction of the middle and lower thirds of the leg, offering good bone coverage.


Resumo Objetivo Descrever e demonstrar o desfecho da técnica modificada de Monteiro (1991) para a reconstrução do membro inferior com retalho fasciocutâneo de pedículo distal numa série de 15 casos. Método Com uma série de 15 casos, apresentamos a técnica e o desfecho da técnica modificada do retalho fasciocutâneo de pedículo distal com para a reparação do terço inferior da perna e do pé. Resultados Os resultados foram satisfatórios porque os retalhos proporcionaram boa cobertura de pele e tecido celular subcutâneo nos casos de exposição óssea e perda cutânea. A área doadora foi fechada 3 dias após a cirurgia, com enxerto de pele de espessura parcial, proporcionando uma melhor viabilidade do enxerto. Conclusão O retalho fasciocutâneo de pedículo distal mostrou-se como uma boa opção para a reconstrução do terço médio e inferior da perna, oferecendo boa cobertura óssea.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Surgical Flaps , Tissue Donors , Bereavement , Skin Transplantation , Lower Extremity , Fascia , Foot , Leg
11.
Arq. ciências saúde UNIPAR ; 24(3): 169-177, set-dez. 2020.
Article in Portuguese, French | LILACS | ID: biblio-1129443

ABSTRACT

Objetivou-se mapear as estratégias educativas utilizadas para estudantes do ensino básico, quanto ao processo de doação e transplante de órgãos e tecidos humanos. Realizou-se uma metassíntese, por meio de uma revisão integrativa da literatura de estudos publicados entre 1990 a 2018, veiculados no portal da Public Medical e nas bases de dados: Scopus, Cumulative Index to Nursing & Allied Health Literature, Embase Subject Headings, Web of Science, Literatura Latino-Americana e do Caribe em Ciências da Saúde, Base de Dados em Enfermagem e Biblioteca Virtual em Saúde do Adolescente. Resultando em 1.331 registros, que após levantamento efetivo, resultaram em 14 artigos selecionados, os quais foram submetidos à leitura criteriosa quanto à metodologia utilizada, ferramentas educativas aplicadas, resultados obtidos e conclusões. Processaram-se sínteses, construídas da análise temática dos resultados, o que permitiu identificar 11 intervenções educativas, representadas, por: dinâmica em grupo (25,0%); palestras com profissionais da área (16,6%); vídeo educativo (13,8%); palestras com candidatos, receptores e familiares que doaram os órgãos para transplante (11,1%); Website interativo (8,3%); Folder explicativo, peça de teatro e intervenção educativa realizada pelos professores em sala de aula, cada um apresenta 5,5% das ferramentas educativas; literatura sobre a temática (fábula), criação de desenhos e premiações como incentivo, representam 2,7%, individualmente. Os estudos demonstram a importância da aplicação de diferentes estratégias educativas e discussões realizadas em sala de aula, quanto ao processo de doação e transplante de órgãos e tecidos humanos, sendo imprescindível a participação dos escolares no processo de construção do conhecimento acerca do tema.


This study aimed at mapping the educational strategies used for students of elementary education regarding the process of donation and transplantation of human organs and tissue. Qualitative meta-synthesis was carried out through an integrative literature review of studies published between 1990 and 2018 published on the Public Medical portal and on the following databases: Scopus; Cumulative Index to Nursing & Allied Health Literature; Embase Subject Headings; Web of Science; Latin American and Caribbean Literature on Health Sciences; Nursing Database and Virtual Library on Adolescent Health. This search resulted in 1,331 records, which after effective survey, resulted in 14 selected articles. Those selected articles were then subjected to thorough reading as to the methodology used, educational tools applied, results obtained and conclusions. Syntheses were processed, constructed from thematic analysis of the results, which allowed the identification of 11 educational interventions, represented by group dynamics (25.0%); lectures with professionals in the area (16.6%); educational video (13.8%); lectures with candidates, recipients and family members who donated the organs for transplant (11.1%); interactive website (8.3%); explanatory folder, play and educational intervention carried out by teachers in the classroom, each one representing 5.5% of the educational tools; literature on the theme (fable), creation of drawings and awards as an incentive, represent 2.7%, individually. The studies demonstrate the importance of the active participation of the students in the teaching-learning process, as well as the propagation, for their families, of the discussions held in the classroom.


Subject(s)
Humans , Male , Female , Students , Organ Transplantation/statistics & numerical data , Health Strategies , Education, Primary and Secondary , Education , Research/statistics & numerical data , Awareness , Tissue Donors/statistics & numerical data , Health Education/statistics & numerical data , Learning
12.
Rev. colomb. cardiol ; 27(5): 461-468, sep.-oct. 2020. tab, graf
Article in Spanish | LILACS, COLNAL | ID: biblio-1289256

ABSTRACT

Resumen Introducción: ¿Cuál es la situación actual técnica y productiva de los cuatro bancos que están certificados en buenas prácticas para tejido cardiovascular en Colombia si se comparan con estándares internacionales? Objetivo: Caracterizar la capacidad técnica y la actividad de los bancos certificados del país para tejido cardiovascular durante el periodo de tiempo 2014 a 2016. Metodología: Mediante una encuesta realizada por vía teleconferencia a cada banco, se evaluaron ítems de donación, extracción, procesamiento, almacenamiento, distribución y capacidad de producción de los tejidos cardiovasculares. La información referida por las instituciones fue complementada con actas de certificación de buenas prácticas del INVIMA y la suministrada por el INS de las estadísticas reportadas por los mismos bancos durante el periodo 2014 a 2016. Resultados: El tejido cardiovascular procesado por los bancos colombianos procede principalmente de donantes con muerte encefálica y es extraído directamente en el quirófano; la edad de los donantes va desde recién nacidos hasta los 60 años. Cuando se requiere, el antibiótico de elección es la vancomicina. El almacenamiento más usado es la criopreservación y su distribución se hace principalmente a grupos quirúrgicos preestablecidos e intrainstitucionales. Conclusiones: El desarrollo del banqueo de este tipo de tejido está muy rezagado en Colombia respecto a otros países, debido a las dificultades de donación, extracción y utilización por grupos con alta experticia; adicionalmente, la normativa utilizada para evaluar estas instituciones está muy desactualizada.


Abstract Introduction: A study is performed to determine if the current technical and productive situation of the four cardiovascular tissue banks that have Good Practice Certificates in Colombia compare with international standards. Objective: To determine the technical capacity and activity of the banks certified by the country for cardiovascular tissue during the period from 2014 to 2016. Methodology: The items analysed using a questionnaire completed by teleconference to each bank were, donation, extraction, processing, storage, distribution, and production capacity of the cardiovascular tissues. The information provided by the institutions was complemented with the Minutes of Good Practice Certification of the Colombia National Food and Drug Surveillance Institute (INVIMA) as well as the statistics reported by the banks themselves and provided by the National Health Institute (INS) during the period 2014 to 2016. Results: The cardiovascular tissue processed by Colombian tissue banks mainly comes from donors with brain death, and is extracted directly in the operating theatre. The age of the donors go from newborn up to 60 years-old. When used, the antibiotic of choice is vancomycin. The most used storage method is cryopreservation, and is mainly distributed to established and institutional surgical groups. Conclusions: The development of this type of tissue bank is lagging behind in Colombia compared to other countries. This is due to the difficulties in donation, extraction, and use by groups with high expertise. Furthermore, the guidelines used to evaluate these institutions are very out of date.


Subject(s)
Tissue Banks , Tissue Donors , Tissue Transplantation
13.
Rev. cir. (Impr.) ; 72(5): 482-491, oct. 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1138744

ABSTRACT

Resumen La donación de órganos en Chile es insuficiente, con una tasa histórica de alrededor de seis donantes por millón de habitantes. Las reformas legales, mejoras organizacionales y campañas comunicacionales han permitido hacer del año 2019 el más exitoso en cuanto a donación de órganos y trasplantes. El trasplante hepático en Chile fue realizado por primera vez en el año 1969 en el Hospital Naval de Valparaíso, falleciendo el receptor precozmente. El primer trasplante exitoso fue realizado en el año 1985 en el Hospital Militar de Santiago. Desde esa fecha hasta la actualidad se han realizado 1.812 trasplantes de hígado, el 43,6% en hospitales universitarios, el 35,1% en clínicas privadas y un 21,5% en hospitales estatales. El 23,1% en la Pontificia Universidad Católica (PUC), el 20,6% en el Hospital Clínico de la Universidad de Chile (HCUCH), el 15,9% en el Hospital Luis Calvo Mackenna (HLCM), el 15,9% en Clínica Las Condes (CLC), el 14,3% en Clínica Alemana de Santiago (CA), el 5,6% en el Hospital del Salvador (HdS), 2% en Clínica Dávila (CD), 2% en el Sanatorio Alemán de Concepción (SA) y 0,9% en Clínica Santa María (CSM) De este total, 455 son en pacientes pediátricos, de ellos 63,3% en Hospital Luis Calvo Mackenna el 21,1% en la Clínica Las Condes el 7,7% en la Pontificia Universidad Católica de Chile, el 6,4% en la Clínica Alemana y 1,5% en el Sanatorio Alemán. Desde el 2015, aproximadamente el 80% de los trasplantes pediátricos se realizan en el HLCM. Sobrevidas reportadas en adultos van del 75% a 85% al año y de 75% a 92% al año en pacientes pediátricos dependiendo el período. Hay centros que nunca han reportado sus resultados. Se espera mejorar la educación en pro de una sociedad proclive en la donación, mejorar la organización de detección, mantención y procuramiento, aumentar la utilización de órganos, potenciar la utilización los de donantes cadáveres, con técnica Split o hígado dividido y, mientras no tengamos un sistema de donación que dé cuenta de las necesidades del país, mantener los programas de donante vivo. Finalmente debe motivarse a generaciones jóvenes para que se dediquen a esta importante actividad.


Organ donation in Chile is insufficient, with a historical rate of six donors per million inhabitants. Legal reforms, organizational improvements, and communications campaigns have made 2019 the most successful year in terms of organ donations and transplants. The first liver transplant in Chile was performed in 1969 at the Naval Hospital in Valparaíso. However, the patient passed away shortly after. The first successful transplant was performed in 1985 at the Militar Hospital in Santiago. As of that date to present day, 1.812 liver transplants have been performed: 43.6% of these in university hospitals, 35.1% in private clinics, and 21.5% in state hospitals. Of these, 23.1% were performed at the Pontificia Universidad Católica de Chile (PUC), 20.6% at the Universidad de Chile Clinical Hospital (HCUCH), 15.9% at the Luis Calvo Mackenna Hospital (HLCM), 15.9% at the Las Condes Clinic (CLC), 14.3% at the Alemana Clinic in Santiago (CA), 5.6% at the del Salvador Hospital (HdS), 2% at the Dávila Clinic (CD), 2% at the Alemán Sanatorium in Concepción (SA), and 0.9% at the Santa María Clinic (CSM). Of this total, 455 correspond to pediatric patients. Of these patients, 63.3% were at the Luis Calvo Mackenna Hospital, 21.1% at the Las Condes Clinic, 7.7% at the Pontificia Universidad Católica de Chile, 6.4% at the Alemana Clinic, and 1.5% at the Alemán Sanatorium. Since 2015, approximately 80% of pediatric transplants are performed at the HLCM. Reported one-year survival range from 75% to 85% in adults and 75% to 92% in pediatric patients per year, depending on the period. Some centers have never reported their results. It is expected that education of a society prone to organ donation improves, as well as improving the detection, maintenance, and procurement of potential donors, increasing the utilization of organs, enhancing the utilization of organs from deceased donors with Split technique, and, while we are building towards a donation system that responds to the needs of the nation, upholding live donor programs. Finally, younger generations are to be motivated so that they dedicate themselves to this important activity.


Subject(s)
Humans , Chile/epidemiology , Liver Transplantation/history , Transplants/statistics & numerical data , Survival , Tissue Donors/statistics & numerical data , Tissue and Organ Procurement/history , Tissue and Organ Procurement/statistics & numerical data
14.
Rev. bras. oftalmol ; 79(5): 296-301, set.-out. 2020. tab
Article in Portuguese | LILACS | ID: biblio-1137980

ABSTRACT

Resumo Objetivo: analisar a influência da escolaridade e do grau de parentesco na decisão familiar pela doação de córneas para transplantes. Método: desenho quantitativo, transversal e retrospectivo com amostra composta por 291 fichas das entrevistas realizadas com familiares de potenciais doadores de córneas de janeiro de 2015 a dezembro de 2017 de um hospital público, geral e de grande porte localizado no município de Porto Alegre, Rio Grande do Sul, Brasil. Resultados: entre os potenciais doadores deste tecido, 53,3% são do sexo masculino com idade média de 57 anos (57±11); 55,7% são casados e o turno mais frequente da ocorrência do óbito é o noturno com 29,6% dos casos. Em relação à decisão familiar, 60,8% dos entrevistados decidiram favoravelmente à doação. Existe associação entre doação e turno da entrevista, sendo a madrugada o menos favorável (p=0,04). O tempo médio entre o óbito e a realização da entrevista é de 1:39 (±1:20) e não influenciou na decisão familiar (p=0,63). Dos familiares entrevistados, 58,8% são do sexo feminino e 53,3% são descendentes do potencial doador. O parentesco descendente decide sobre a doação com maior frequência do que ascendentes, laterais ou cônjuges. A faixa etária do familiar entrevistado (41±13) tem diferença estatística em relação a do potencial doador. Há diferença entre decisão de doação e nível de escolaridade (p=0,03) sendo que familiares com maior escolaridade decidem com maior frequência favoravelmente a doação. Conclusões: escolaridade do familiar, grau de parentesco e turno da entrevista influenciam na decisão positiva para a doação de córneas para transplantes.


Abstract Objective: analyzing the influence of schooling and kinship on families' decision to donate corneas for transplants. Method: quantitative, cross-sectional and retrospective study whose sample comprised 291 records of interviews conducted with family members of potential corneal donors from January 2015 to December 2017, who were treated in a public, general and large-sized hospital in Porto Alegre City, Rio Grande do Sul State, Brazil. Results: 53.3% of the potential corneal donors were male at mean age of 57 years (57 ± 11); 55.7% were married and 29.6% of them died during the night shift, which was the shift when death took place more often. With respect to families' decision, 60.8% of interviewees decided for donation. There was association between donation and interview shift; dawn was the least favorable time (p = 0.04). The mean time between patients' death and the interview with family members was 1:39 (± 1: 20) and it did not influence families' decision (p = 0.63). Among the interviewed family members, 58.8% were women and 53.3% were descendants of the potential donor. Descendants decide about the donation more often than ascendants, siblings or spouses. The age group of the interviewed family members (41 ± 13) was statistically different from that of potential donors. There was association between schooling and decision to donate (p = 0.03); family members with higher schooling were more often favorable towards donation. Conclusions: Family members' schooling, degree of kinship and interview shift had positive influence on individuals' decision to donate corneal tissue for transplants.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Tissue Donors , Tissue and Organ Procurement , Interviews as Topic , Cornea , Educational Status , Family Relations , Cross-Sectional Studies , Retrospective Studies , Evaluation Studies as Topic
15.
Rev. cuba. hematol. inmunol. hemoter ; 36(3): e1277, jul.-set. 2020. tab, graf
Article in Spanish | LILACS, CUMED | ID: biblio-1156444

ABSTRACT

Introducción: La aplasia medular adquirida grave es una enfermedad hematológica infrecuente caracterizada por una disminución o ausencia de precursores hematopoyéticos en la médula ósea, lo cual se expresa con distintos grados de citopenias. Varios factores, infecciosos o no, pueden incidir en su origen. Su manejo es complejo y puede incluir tratamiento inmunosupresor y trasplante de progenitores hematopoyéticos alogénico. Objetivo: Demostrar la utilidad de la realización del trasplante de progenitores hematopoyéticos alogénico haploidéntico en pacientes con aplasia medular grave. Caso clínico: Paciente masculino de 21 años de edad, con antecedentes de salud, que en octubre del 2018 debutó con íctero, pancitopenia, lesiones purpúrico hemorrágicas en piel y mucosas, en el curso de una hepatitis aguda seronegativa. La biopsia de médula ósea mostró aplasia medular severa. Se inició tratamiento inmunosupresor con globulina antitimocίtica, ciclosporina A y metilprednisolona. Al cabo de los 6 meses mantenía trombocitopenia severa con necesidades transfusionales y en octubre de 2019 se decide realizar trasplante de progenitores hematopoyéticos alogénico con donante haploidéntico y empleando como tratamiento acondicionante globulina antitimocίtica, fludarabina, ciclofosfamida y bajas dosis de irradiación corporal total. En evaluación clίnica de julio de 2020 (dίa + 280 del trasplante) el paciente estaba asintomático y con parámetros hematológicos normales. Conclusiones: Se demostró que el trasplante de progenitores hematopoyéticos alogénico haploidéntico es un proceder realizable y útil en pacientes con aplasia medular grave, lo cual corrobora el beneficio clínico que puede aportar su ejecución en pacientes con esta enfermedad(AU)


Introduction: Acquired severe marrow aplasia is a rare hematological disease characterized by decrease or absence of hematopoietic precursors in bone marrow, which is expressed with different degrees of cytopenias. Several factors, infectious or not, can influence its origin. Its management is complex and may include immunosuppressive treatment and allogeneic hematopoietic stem-cell transplantation. Objective: To demonstrate the usefulness of performing haploidentical allogeneic hematopoietic stem-cell transplantation in patients with severe medullary aplasia. Clinical case: A 21-year-old male patient, with medical history, who first presented, in October 2018, with icterus, pancytopenia, as well as purpuric hemorrhagic lesions on the skin and mucosa, in the course of acute seronegative hepatitis. The bone marrow biopsy showed severe marrow aplasia. Immunosuppressive treatment was started with antithymocytic globulin, cyclosporine A, and methylprednisolone. After six months, he maintained severe thrombocytopenia under transfusion requirements and, in October 2019, the decision was to perform allogeneic hematopoietic stem-cell transplantation with a haploidentical donor and using antithymocyte globulin, fludarabine, cyclophosphamide, and low doses of total body irradiation as conditioning treatment. In the clinical assessment carried out in July 2020 (day +280 after transplantation), the patient was asymptomatic and with normal hematological parameters. Conclusions: Transplantation of haploidentic allogeneic hematopoietic progenitors was shown to be a feasible and useful procedure in patients with severe marrow aplasia, which corroborates the clinical benefit that its execution can bring in patients with this disease(AU)


Subject(s)
Humans , Male , Young Adult , Tissue Donors/ethics , Methylprednisolone/therapeutic use , Whole-Body Irradiation/methods , Microscopy, Electron, Scanning Transmission/methods , Hematologic Diseases , Hematopoietic Stem Cell Transplantation/methods , Cuba , Transplantation, Haploidentical/methods , Anemia, Aplastic/therapy , Antilymphocyte Serum
16.
Caracas; Observatorio Nacional de Ciencia, Tecnología e Innovación; ago. 2020. 53-56 p. ilus.(Observador del Conocimiento. Revista Especializada en Gestión Social del Conocimiento, 5, 2).
Monography in Spanish | LILACS, LIVECS | ID: biblio-1118410

ABSTRACT

El uso de Plasma de Convaleciente de COVID-19 (PC-CoV19) como coadyuvante en el tratamiento de pacientes, tendría impacto socioeconómico importante al disminuir el periodo de estancia hospitalaria y letalidad por la enfermedad. La determinación de anticuerpos en plasma de potenciales donantes es criterio fundamental para su selección. Existe dificultad para disponer de pruebas serológicas certificadas que cuantifiquen anticuerpos específicos contra SARS-CoV-2. Las Pruebas de Diagnóstico Rápido (PDR) se convierten en herramienta útil y al alcance para la selección de pacientes recuperados, potenciales donantes de PC-CoV19. Este estudio evaluó el porcentaje de positividad de diferentes PDR en veintidós (22) muestras de pacientes con COVID-19 confirmada por RT-PCR. Las muestras se analizaron siguiendo el procedimiento descrito por cada fabricante. Se analizó el comportamiento de las PDR en pacientes sintomáticos y asintomáticos en diferentes momentos de la enfermedad. El porcentaje de positividad fue de 100% con dos de las tres pruebas utilizadas, una de las cuales discrimina IgM de IgG. Se concluye que la presencia de IgG se registra a partir de los 15 días del inicio de los síntomas y se mantiene presente a los 59 días de evolución en los pacientes sintomáticos, y que pacientes asintomáticos podrían ser considerados candidatos a donantes de PC-CoV19 pues se evidenció seroconversión para IgG. El porcentaje de positividad a IgG podría disminuir en los pacientes recuperados. Se sugiere que pacientes sintomáticos con criterio de alta médica sean considerados candidatos donantes en momento posterior a 28 días de la fecha de inicio de los síntomas. Se recomienda utilizar PDR que discriminen IgM de IgG como herramienta para la selección de donantes de PC-CoV19(AU)


The use of COVID-19 Convales-cent Plasma (PC-CoV19) as an ad-juvant for the treatment of patients, would have a significant socioeconomic impact by reducing the leng-th of hospital stay and lethality due to the disease. The determination of antibodies in plasma from potential donors is a fundamental criterion for their selection. There is dificulty in obtaining certified serological tests that quantify specific antibodies against SARS-CoV-2. Rapid Diagnostic Tests (PDR) become a useful and accessible tool in the selection of recovered patients, potential PC-CoV19 donors. This study evaluated the positivity rate of different PDRs in twenty two (22) samples from patients with COVID-19 confirmed by RT-PCR. The samples were analyzed following the procedure described by each manufacturer. The performance of PDRs was analyzed in symptomatic and asymptomatic patients at different times of the disease. The positivity rate was 100% with two of the three tests used, one of which discriminates IgM from IgG. It is concluded that the presence of IgG is recorded 15 days after the onset of symptoms and remains present at day 59 of evolution in symptomatic patients, and that asymptomatic patients could be considered candidates for PC-CoV19 donors since IgG se-reconversion was evident. The positivity rate to IgG could decrease in the recovered patients. It is suggested that symptomatic patients with medical discharge criteria be considered donor candidates after 28 days from the date of onset of symptoms. It is recommended to use PDRs that discriminate IgM from IgG as a tool for the selection of PC-CoV19 donors


Subject(s)
Humans , Plasma , Tissue Donors , Immunoglobulin G/therapeutic use , Immunoglobulin M , Serologic Tests , Coronavirus Infections , Diagnostic Tests, Routine
17.
Rev. bras. cir. cardiovasc ; 35(4): 484-489, July-Aug. 2020. tab, graf
Article in English | LILACS, SES-SP | ID: biblio-1137304

ABSTRACT

Abstract Objective: To investigate the effect of Shenfu (SF) injection on donor heart preservation. Methods: Twelve pigs were randomly divided into SF group (n=6) and control group (n=6). After eight hours of perfusion, the differences in hemoglobin, the expression of Bcl-2 and BAX, and changes in the myocardial ultrastructure were compared to illustrate the effects of SF injection in heart preservation. Results: The differences in free hemoglobin between the SF group and the control group were statistically significant (P=0.001), and there was significant interaction of groups with times (P=0.019), but the perfusion time may not be associated with the hemoglobin concentration (P=0.616). According to Western blotting analysis, the expression of Bcl-2 was higher in the SF group than in the control group, while the expression of BAX was not different between the two groups. As to ultrastructural changes, both groups exhibited mitochondrial swelling and myofilament lysis, but the degree of damage in the SF group was smaller. Conclusion: Our study suggests that the application of SF injection for heart preservation may protect against cardiomyocytes and erythrocytes apoptosis, and Bcl-2 protein may play a role in these physiological processes.


Subject(s)
Animals , Male , Drugs, Chinese Herbal , Heart Transplantation , Swine , Swine, Miniature , Tissue Donors
18.
Int. j. morphol ; 38(4): 831-837, Aug. 2020. tab
Article in English | LILACS | ID: biblio-1124862

ABSTRACT

The aim of this study was to evaluate the awareness, knowledge level and attitudes of the community in I˙zmir/ Turkey about cadaver donation in medical education. A cross-sectional study was carried out. Randomly chosen 245 participants answered twenty items in the questionnaire providing information about their demographics (5 items), awareness and knowledge (10 items), and attitudes (5 items) about body donation. The questionnaire was applied face-to-face. Descriptive statistics presented. Student T test and One-Way ANOVA test were used for statistical analysis. 123 (50.2 %) participants were male and 159 (64.9 %) were between 30 to 59 years old. 185 (75.5 %) respondents knew what the word "cadaver" means. When asked where they would apply if they decided to donate their body, 104 (42.4 %) of the participants gave the answer "state hospital". The mean score of awareness and knowledge about importance of cadaver and body donation (AWKL-Score) was 0.41±0.24 (min:0.00, max:0.90). AWKL-Score was statistically higher in the youngest (18-29 y) and oldest (>60 y) compared to the other age groups (F:4.115; p:0.007). AWKL-Score increased as the level of education increased. The highest AWKL-Score was at post-graduate level (Level 7,8) (F:22.997; p<0.001). The AWKL-Score was higher in public employees and students compared to other occupational groups (F:5.930; p<0,001). The answers to the questionnaire were important indicators of how much society needs to be informed regarding body donation.


El objetivo de este estudio fue evaluar el nivel de conciencia, conocimiento y las actitudes de la comunidad en Izmir / Turquía sobre la donación de cadáveres en la educación médica. Se realizó un estudio transversal de 245 participantes elegidos al azar, que respondieron veinte ítems en el cuestionario proporcionando información sobre su demografía (5 ítems), conciencia y conocimiento (10 ítems) y actitudes (5 ítems) sobre la donación de cuerpos. El cuestionario fue administrado directamente en persona; la prueba T de Student y la prueba ANOVA de una vía se utilizaron para el análisis estadístico. De los participantes 123 (50,2 %) eran hombres y 159 (64,9 %) tenían entre 30 y 59 años. 185 (75,5 %) encuestados sabían lo que significa la palabra "cadáver". Cuando se les preguntó dónde se registrarían, en caso de decidir donar su cuerpo, 104 (42,4 %) de los participantes respondieron "hospital estatal". La puntuación media de conciencia y conocimiento sobre la importancia del cadáver y la donación de cuerpos (puntuación AWKL) fue de 0,41 ± 0,24 (mínimo: 0,00, máximo: 0,90). Estadísticamente el puntaje AWKL fue más alto en los más jóvenes (18-29 años) y mayores (> 60 años) en comparación con los otros grupos etarios (F: 4,115; p: 0.007). AWKL-Score aumentó a medida que aumentó el nivel de educación. El puntaje AWKL más alto fue en el nivel de posgrado (Nivel 7,8) (F: 22,997; p <0,001). El puntaje AWKL fue mayor en empleados públicos y estudiantes en comparación con otros grupos ocupacionales (F: 5,930; p <0,001). Las respuestas al cuestionario fueron indicadores importantes de cuánto necesita la sociedad estar informada sobre la donación de cuerpos.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Tissue Donors/psychology , Cadaver , Health Knowledge, Attitudes, Practice , Anatomy/education , Turkey , Cross-Sectional Studies , Surveys and Questionnaires , Analysis of Variance , Conscience , Education, Medical
19.
Rev. bras. ortop ; 55(4): 410-414, Jul.-Aug. 2020. tab, graf
Article in English | LILACS | ID: biblio-1138056

ABSTRACT

Abstract Objective To evaluate different decontaminants for tendon grafts, proposing an antiseptic protocol for contaminated grafts. Methods A total of 25 patients were tissue donors for the study. Each participant donated a 2.5-cm tendon sample, which was divided into 5 fragments with 5 mm each during anterior cruciate ligament (ACL) reconstruction surgery. The collected material was divided into 5 groups, totaling 125 samples. In total, four fragments of each patient were placed on the operating room floor for one minute for contamination, simulating the fall of the graft on the floor during surgery. The other fragment was immediately placed in a sterile container (group 1). One of the contaminated fragments was placed in the sterile container without being previously immersed in decontaminating solution (group 2). The remaining fragments were immersed for ten minutes in decontaminating solution: 0.5% chlorhexidine (group 3), 0.9% saline (group 4) and 0.55% ortho-phthalaldehyde (group 5), and, after this time, they were individually placed in a sterile container. The samples from the 5 groups were submitted to microbiological examination. Results Bacteria were detected in 26% of the total samples in the microbiological tests, and in group 1 there was no growth of microorganisms. In group 2, bacterial growth was observed in 16 samples. Considering the evaluation of test groups 3, 4 and 5, the percentage of decontamination was higher than the growth of microorganisms in the respective cultures. Conclusion The protocol suggested by the study showed that intraoperative graft decontamination is possible.


Resumo Objetivo Avaliar diferentes descontaminantes para enxertos de tendões, propondo um protocolo de antissepsia para o enxerto contaminado. Métodos Um total de 25 pacientes foram doadores de tecido para o estudo. Cada participante doou uma amostra de 2,5 cm de tendão, a qual foi dividida em 5 fragmentos de 5 mm durante cirurgia de reconstrução do ligamento cruzado anterior (LCA). O material coletado foi dividido em 5 grupos, totalizando 125 amostras. Ao todo, quatro fragmentos de cada paciente foram colocados sobre o piso da sala cirúrgica, durante um minuto, para contaminação, simulando a queda do enxerto no chão durante o ato operatório. O outro fragmento foi, imediatamente, colocado em um recipiente esterilizado (grupo 1). Um dos fragmentos contaminados foi colocado no recipiente esterilizado sem ser previamente imerso em solução descontaminante (grupo 2). Os demais fragmentos foram imersos, por dez minutos, em solução descontaminante: clorexidina 0,5% (grupo 3), soro fisiológico 0,9% (grupo 4) e ortoftaldeído 0,55% (grupo 5), e, após esse tempo, foram colocados individualmente em um recipiente esterilizado. As amostras dos 5 grupos foram submetidas a exame microbiológico. Resultados Houve detecção de bactérias em 26% do total de amostras nos testes microbiológicos, sendo que no grupo 1 não houve crescimento de micro-organismos. No grupo 2, observou-se crescimento bacteriano em 16 amostras. Avaliando-se os grupos de teste 3, 4 e 5, o percentual de descontaminação foi superior ao crescimento de micro-organismos nas respectivas culturas. Conclusão O protocolo sugerido pelo estudo mostrou que é possível a descontaminação transoperatória do enxerto.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Operating Rooms , Tendons , Tissue Donors , Chlorhexidine , Antisepsis , Decontamination , Anterior Cruciate Ligament , Determination , Transplants , Autografts
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