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1.
Rev. bras. oftalmol ; 80(2): 146-150, Mar.-Apr. 2021. graf
Article in English | LILACS | ID: biblio-1280111

ABSTRACT

ABSTRACT We propose a novel surgical technique in cases of aggressive recurrent pterygium non-subsidiary of treatment with conjunctival autografts or antimetabolites. Two presented cases were treated with surgical excision and a sutured plasma rich in growth factors membrane (mPRGF) followed by rich in growth factors (PRGF) eye drops treatment. After surgery, dexamethasone, tobramycin and PRGF eye drops were prescribed for 6 weeks. After a 12-month and 3-year post-surgical follow-up respectively, treated eyes with mPRGF did not present relapse, and visual acuity improved in both cases. No ocular complications, pain, eye discomfort nor other symptoms were observed. The combined use of PRGF eye drops and mPRGF seems an effective and safe therapy for recurrent pterygium.


RESUMO Nós propomos uma nova técnica cirúrgica em casos de pterígio agressivo recorrente não subsidiário de tratamento com autoenxertos conjuntivais ou antimetabólitos. Dois casos foram tratados com excisão cirúrgica e um plasma suturado rico em membrana de fatores de crescimento (mPRGF), seguido de tratamento com colírios ricos em fatores de crescimento (PRGF). Após a cirurgia, foram prescritos colírios de dexametasona, tobramicina e PRGF por 6 semanas. Após 12 meses e 3 anos de acompanhamento pós-cirúrgico respectivamente, os olhos tratados com mPRGF não apresentaram recidiva e a acuidade visual melhorou nos dois casos. Não foram observadas complicações oculares, dor, desconforto ocular ou outros sintomas. O uso combinado de colírios de PRGF e mPRGF parece uma terapia eficaz e segura para o pterígio recorrente.


Subject(s)
Humans , Male , Middle Aged , Aged , Pterygium/surgery , Platelet-Rich Plasma , Platelet-Rich Fibrin , Ophthalmic Solutions , Recurrence , Reoperation , Ophthalmologic Surgical Procedures/methods , Biological Dressings , Fibrin/therapeutic use , Platelet Activation , Tissue Transplantation/methods , Tissue Engineering
2.
Int. j. odontostomatol. (Print) ; 14(4): 602-609, dic. 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1134546

ABSTRACT

RESUMEN: Comparar mediante una revisión sistemática los resultados clínicos de los procedimientos de cirugía plástica periodontal/periimplantar (CP) con injerto de tejido blando autógeno (ITB) obtenido del área lateral del paladar (ALP) versus del área de la tuberosidad (AT). Se realizó una búsqueda electrónica de ensayos clínicos en la base de datos Medline/Pubmed, Cochrane y las revistas de Periodoncia e Implantes de mayor impacto según la Web of Science, para hallar artículos publicados hasta abril del 2020. Se valoró el riesgo de sesgo de los artículos añadidos según el manual Cochrane Versión 5.1.0 para ensayos clínicos aleatorizados y la escala Newcastle-Ottawa para ensayos clínicos controlados. De una muestra inicial de 930 artículos, cuatro ensayos clínicos (tres aleatorizados) fueron incluidos en el presente estudio, donde se realizaron un total de 87 CP alrededor de piezas e implantes dentales, de las cuales 42 cirugías fueron realizadas con ITB del ALP y 45 cirugías con ITB del AT, se evaluó los resultados desde las 8 semanas hasta los 12 meses. No se hallaron diferencias estadísticamente significativas en los resultados clínicos entre ambos grupos, se mejoró el fenotipo gingival en la zona receptora para el grupo que obtuvo el ITB del AT y el nivel del dolor del sitio donador del AT fue menor en las dos primeras semanas que el sitio donante del ALP. Los estudios incluidos manifestaron un bajo riesgo de sesgo en promedio. Ambas áreas donantes de injerto de tejido blando proporcionan resultados clínicos similares, el injerto del área de la tuberosidad mejora el fenotipo gingival de la zona receptora y reduce el dolor post operatorio en las primeras semanas del sitio donador.


ABSTRACT: The objective of the study was to compare, through a systematic review, the clinical results of periodontal / peri-implant plastic surgery (CP) procedures with autogenous soft tissue graft (ITB) obtained from the lateral palate area (ALP) versus the tuberosity area (AT). We conducted an electronic search of clinical trials in the Medline/Pubmed, Cochrane database and the journals of Periodontics and Implants with the greatest impact according to the Web of Science, to find articles published until April 2020. The risk of bias of the articles added was assessed according to the Cochrane Manual Version 5.1.0 for randomized clinical trials and the Newcastle-Ottawa scale for controlled clinical trials. From the initial sample of 930 articles, four clinical trials were included (three randomized) in the present study, where a total of 87 PC were performed around dental pieces and implants, of which 42 surgeries were performed with ITB of the ALP and 45 surgeries with ITB of the AT, the results were evaluated from the 8 weeks to 12 months. No statistically significant differences were found in the clinical results between the two groups, the gingival phenotype in the receiving area was improved for the group that obtained the ITB of the AT and the level of pain at the donor site was lower in the first two weeks than the ALP donor site. The studies showed a lowrisk of bias on average. Both soft tissue graft donor areas provide similar clinical results, grafting the tuberosity area improves the gingival phenotype of the recipient area and reduces post-operative pain of the donor site in the first few weeks.


Subject(s)
Humans , Dental Implants/statistics & numerical data , Oral Surgical Procedures , Dental Implantation, Endosseous , Palate , Transplantation, Autologous , Selection Bias , Tissue Transplantation , Connective Tissue/transplantation , Gingival Recession
3.
Rev. colomb. cardiol ; 27(5): 461-468, sep.-oct. 2020. tab, graf
Article in Spanish | LILACS, COLNAL | ID: biblio-1289256

ABSTRACT

Resumen Introducción: ¿Cuál es la situación actual técnica y productiva de los cuatro bancos que están certificados en buenas prácticas para tejido cardiovascular en Colombia si se comparan con estándares internacionales? Objetivo: Caracterizar la capacidad técnica y la actividad de los bancos certificados del país para tejido cardiovascular durante el periodo de tiempo 2014 a 2016. Metodología: Mediante una encuesta realizada por vía teleconferencia a cada banco, se evaluaron ítems de donación, extracción, procesamiento, almacenamiento, distribución y capacidad de producción de los tejidos cardiovasculares. La información referida por las instituciones fue complementada con actas de certificación de buenas prácticas del INVIMA y la suministrada por el INS de las estadísticas reportadas por los mismos bancos durante el periodo 2014 a 2016. Resultados: El tejido cardiovascular procesado por los bancos colombianos procede principalmente de donantes con muerte encefálica y es extraído directamente en el quirófano; la edad de los donantes va desde recién nacidos hasta los 60 años. Cuando se requiere, el antibiótico de elección es la vancomicina. El almacenamiento más usado es la criopreservación y su distribución se hace principalmente a grupos quirúrgicos preestablecidos e intrainstitucionales. Conclusiones: El desarrollo del banqueo de este tipo de tejido está muy rezagado en Colombia respecto a otros países, debido a las dificultades de donación, extracción y utilización por grupos con alta experticia; adicionalmente, la normativa utilizada para evaluar estas instituciones está muy desactualizada.


Abstract Introduction: A study is performed to determine if the current technical and productive situation of the four cardiovascular tissue banks that have Good Practice Certificates in Colombia compare with international standards. Objective: To determine the technical capacity and activity of the banks certified by the country for cardiovascular tissue during the period from 2014 to 2016. Methodology: The items analysed using a questionnaire completed by teleconference to each bank were, donation, extraction, processing, storage, distribution, and production capacity of the cardiovascular tissues. The information provided by the institutions was complemented with the Minutes of Good Practice Certification of the Colombia National Food and Drug Surveillance Institute (INVIMA) as well as the statistics reported by the banks themselves and provided by the National Health Institute (INS) during the period 2014 to 2016. Results: The cardiovascular tissue processed by Colombian tissue banks mainly comes from donors with brain death, and is extracted directly in the operating theatre. The age of the donors go from newborn up to 60 years-old. When used, the antibiotic of choice is vancomycin. The most used storage method is cryopreservation, and is mainly distributed to established and institutional surgical groups. Conclusions: The development of this type of tissue bank is lagging behind in Colombia compared to other countries. This is due to the difficulties in donation, extraction, and use by groups with high expertise. Furthermore, the guidelines used to evaluate these institutions are very out of date.


Subject(s)
Tissue Banks , Tissue Donors , Tissue Transplantation
4.
Rev. cuba. estomatol ; 57(1): e2199, ene.-mar. 2020. tab
Article in Spanish | LILACS, CUMED | ID: biblio-1126481

ABSTRACT

RESUMEN Objetivo: Comparar los cambios dimensionales de los tejidos peri-implantarios en la zona estética, después de la segunda etapa quirúrgica de injertos de tejido conectivo autógeno comparados con una matriz de colágeno xenogénica, después de 3 meses de cicatrización. Métodos: En una serie de casos de seis pacientes con defectos del reborde alveolar, se realizó un procedimiento de aumento de volumen de tejidos blandos, asignando al azar dos modalidades de tratamiento: injerto de tejido conectivo subepitelial y matriz de colágeno dérmica acelular. Para evaluar los cambios dimensionales se tomaron impresiones antes del aumento y a los 90 días; estas fueron vaciadas para obtener modelos de yeso que fueron digitalizados; las dos imágenes fueron superpuestas; y tras la definición de tres puntos de interés, se calculó mediante un Software (D500 3D dental scanner - 3Shape, Copenhague, Dinamarca), los cambios dimensionales en milímetros. Se indagó por el dolor experimentado por los pacientes usando una escala visual análoga. Resultados: A los 90 días de realizada la cirugía, se observó un aumento en el grosor de los tejidos blandos peri-implantarios de 0,77 mm (rango 0,0-1,3) para el injerto de tejido conectivo, y 0,89 mm (rango 0,3-1,5) para la matriz dérmica acelular. No se encontraron diferencias estadísticamente significativas entre las dos modalidades de tratamiento, en ninguno de los tres puntos evaluados por paciente (p= 0,83; p= 0,83; p= 0,51). En cuanto al dolor experimentado entre el primer y séptimo días, no se encontraron diferencias estadísticamente significativas en la zona receptora intergrupo (p= 0,07; p= 0,12); intragrupo, injerto (p= 0,11) y matriz (p= 0,32); ni en la zona donante del grupo del injerto (p= 0,11). Conclusiones: El aumento en el grosor de los tejidos peri-implantarios fue similar después de 90 días en los dos grupos del estudio(AU)


ABSTRACT Objective: Compare the dimensional changes of peri-implant tissues from the esthetic zone after the second surgical stage of autogenous connective tissue grafting vs. a xenogenic collagen matrix after three months' healing. Methods: A case-series of six patients with alveolar ridge defects underwent a soft tissue volume augmentation procedure, randomly assigning two treatment modes: subepithelial connective tissue graft and acellular dermal collagen matrix. Impressions were taken before augmentation and at 90 days to evaluate the dimensional changes. These were then emptied to obtain plaster models which were then digitalized. The two images were superimposed, and upon definition of three points of interest, the dimensional changes were estimated in millimeters with the software D500 3D dental scanner (3Shape, Copenhagen, Denmark). Inquiries were made about the pain experienced by patients using a visual analogue scale. Results: Ninety days after surgery, increase in thickness of peri-implant soft tissues was 0.77 mm (range 0.0-1.3) for the connective tissue graft and 0.89 mm (range 0.3-1.5) for the acellular dermal matrix. No statistically significant differences were found between the two treatment modes at any of the three points evaluated per patient (p= 0.83, p= 0.83, p= 0.51). With respect to the pain experienced between the first and the seventh days, no statistically significant differences were found in the recipient zone intergroup (p= 0.07, p= 0.12), the graft intragroup (p= 0.11) and the matrix (p= 0.32), or in the donor zone of the graft group (p= 0.11). Conclusions: Increase in the thickness of peri-implant tissues after 90 days was similar in the two study groups(AU)


Subject(s)
Humans , Dental Implants/adverse effects , Tissue Transplantation/methods , Alveolar Ridge Augmentation/methods , Epidemiology, Descriptive , Observational Studies as Topic
5.
Arq. odontol ; 56: 1-7, jan.-dez. 2020. ilus
Article in Portuguese | LILACS, BBO | ID: biblio-1097355

ABSTRACT

Objetivo:O objetivo desta revisão foi realizar uma análise crítica da literatura quanto à utilização do procedimento enxerto de tecido conjuntivo e da membrana de fibrina rica em plaquetas para recobrimento da raiz exposta, frisando os benefícios e previsibilidade de sucesso de cada uma. Métodos:Foi realizada uma busca nas bases PubMed, SciELO e BIREME em março de 2019, sendo incluídos estudos relevantes relacionados ao tema para síntese deste trabalho. Resultados: Foram selecionados 5 artigos para serem incluídos nessa revisão crítica, sendo 3 ensaios clínicos controlados randomizados, 1 ensaio clínico e 1 um relato de caso. Conclusão:O recobrimento radicular com uso de enxerto de tecido conjuntivo e fibrina rica em plaquetas apresentou resultados satisfatórios, devolvendo estética, saúde e regeneração dos tecidos gengivais e periodontais. Em relação à fibrina rica em plaquetas, há poucos casos na literatura quanto aos resultados clínicos a longo prazo.


Aim: This review sought to perform a critical analysis of the literature regarding the use of the graft procedure of connective tissue and Platelet-rich fibrin to cover the exposed root, emphasizing the benefits and predictability of success of each. Methods: This study performed a search on the PubMed, SciELO, and BIREME databases, and included relevant studies related to the topic for the synthesis of this work. Results:Five articles were selected to be included in this critical review, three randomized controlled clinical trials, one clinical trial, and one case report. Conclusion:The root covering using a subepithelial connective tissue graft and platelet-rich fibrin presents satisfactory results, restoring esthetics and health, and regenerating the gingival and periodontal tissues. Regarding platelet-rich fibrin, there are few cases in the literature regarding long-term clinical outcomes.


Subject(s)
Connective Tissue , Linings , Platelet-Rich Fibrin , Gingival Recession , Transplantation, Autologous , Tissue Transplantation
6.
Article in Spanish | LILACS | ID: biblio-1058328

ABSTRACT

RESUMEN: Se describe el caso clínico de una paciente de 60 años, sexo femenino, sana, la cual presentaba en el diente 1.1 una recesión de 6 mm de longitud con extensa pérdida ósea en vestibular correspondiente a una clase 3 de Elian. En el presente reporte se expone los pasos que se siguieron para llegar a una Clase 2 de Elian, mediante un colgajo desplazado lateral con injerto de tejido conjuntivo subepitelial.


ABSTRACT: We describe the clinical case of a 60-year-old female patient, healthy, who presented a 6mm-long recession on tooth 1.1 with extensive vestibular bone loss corresponding to an Elian class 3. In the present report, the steps followed to reach an Elian class 2,by means of a laterally moved flap with subepithelial connective tissue graft, are shown.


Subject(s)
Humans , Female , Middle Aged , Regeneration , Tissues , Tooth , Tissue Transplantation
7.
Rev. cuba. estomatol ; 56(4): e2137, oct.-dez. 2019. graf
Article in Spanish | LILACS | ID: biblio-1093259

ABSTRACT

RESUMEN Introducción: La recesión periodontal es un problema mucogingival frecuente, de origen multifactorial que usualmente se asocia a hipersensibilidad dentinaria, caries radicular y problemas estéticos. La cobertura radicular es parte integral de su tratamiento quirúrgico. Las técnicas bilaminares con injerto de tejido conectivo subepitelial son las más predecibles. Objetivo: Describir los resultados clínicos obtenidos al realizar en recesiones periodontales múltiples, injerto de tejido conectivo subepitelial cubierto por colgajo reposicionado coronal modificado. Presentación del caso: Paciente masculino, blanco, obrero, de 43 años, con antecedentes personales y familiares de salud que acudió al Servicio de Periodoncia de la Clínica Estomatológica "III Congreso del PCC", Matanzas, Cuba, por "cambio de posición de la encía en algunos dientes". Clínicamente existía exposición radicular en los dientes 13, 53 y 14, ausencia del 12, higiene bucal adecuada, no presencia de bolsas periodontales. Se diagnosticó recesión periodontal clase I de Miller localizada en dichos dientes. Para su tratamiento quirúrgico se realizó injerto de tejido conectivo subepitelial y colgajo desplazado coronal sin incisiones verticales de 11 a 15. A la semana, se retiró sutura de zona donante, se observó buena cicatrización. Se citó a los siete días para retirar cemento quirúrgico y sutura de la zona injertada; existía discreto edema, materia alba, biopelícula y cobertura radicular completa del 13, 53 y 14. Al año del procedimiento, las superficies expuestas estaban completamente cubiertas con tejido gingival posicionado en 13 y 53, ganancia de encía insertada y armonía de color entre sitio injertado y área adyacente. El 14 mostró 1 mm de raíz expuesta. Conclusiones: La técnica empleada, cubrió totalmente la superficie radicular del 13, del 53 y parcialmente la raíz del 14. Se obtuvo incremento de encía queratinizada, óptimo aspecto estético y buena evolución posoperatoria(AU)


ABSTRACT Introduction: periodontal recession is a frequent mucogingival problem, of multifactorial origin that is usually associated to dentin hypersensibility, radicular caries and esthetic problems. Root coverage is an integral part of its surgical treatment, considering bilaminar techniques with subepithelial connective tissue graft as the most predictable ones. Objective: to describe the clinical results obtained when making a sub epithelial connective tissue graft covered by a modified coronal repositioned flap, in multiple periodontal recessions. Case presentation: a male, white, worker patient, aged 43 years, with health personal and family antecedents, who assisted the Periodontics service of the Dental Clinic "III Congreso del Partido", of Matanzas, Cuba, for "a change of the gum position in some teeth". Clinically, there it was a root exposition of the 13, 53 and 14 teeth, lack of the 12 one, adequate oral hygiene and absence of periodontal´s pockets. A Miller´s Class I periodontal recession located in those teeth was diagnosed. A subepithelial connective tissue graft and coronally advanced flap was performed without vertical incisions from 11 to 15 teeth. After a week, the suture of the donor zone was retired, showing good healing. He was cited at the seventh day to retire surgical cement and suture form the grafted zone, observing a discrete edema, debris, biofilm and complete root coverage of the 13, 53 and 14 teeth. At the year after the procedure, the exposed surface was completely covered with gingival tissue positioned in the 13 and 53 teeth, with a gaining of inserted gum and color harmony between the grafted site and adjacent areas. The 14 tooth showed 1 mm of exposed root. Conclusions: the used technique totally covered the root of the 13 and the 53, and most of the root of the 14 tooth, reaching an increase of the keratinized gum, and optimal esthetic aspect and post-surgery evolution(AU)


Subject(s)
Humans , Male , Adult , Surgical Flaps/surgery , Tissue Transplantation/adverse effects , Gingival Recession/diagnostic imaging
8.
Article in Spanish | LILACS | ID: biblio-1020670

ABSTRACT

RESUMEN: Este caso clínico de boca dividida tiene como objetivo comparar los resultados clínicos obtenidos a 6 meses mediante el uso de técnica VISTA, en combinación con injerto de tejido conectivo (ITC) versus Mucograft® en el tratamiento de recesiones gingivales III de Miller, con fenotipo gingival fino. El resultado muestra que ambos injertos logran mejorar el fenotipo gingival y un mayor porcentaje de cobertura radicular, sin embargo, el ITC provee mayor volumen gingival. No obstante, el Mucograft® proporciona mejores resultados estéticos y menor morbilidad.


ABSTRACT: The aim of this split mouth study, is to compare the results obtained in 6 month follow-up by using VISTA technique in combination with connective tissue graft (CTG) versus Mucograft® in the treatment of Miller´s III gingival recessions, with thin gingival phenotype. The results show that both grafts improve the gingival phenotype and provide higher root coverage percentage, however, CTG provides more gingival volume. Nevertheless, Mucograft® shows better aesthetic results and lower morbidity.


Subject(s)
Humans , Female , Middle Aged , Surgery, Oral , Therapeutics , Tissue Transplantation , Connective Tissue , Gingival Recession
9.
Rev. ecuat. pediatr ; 20(1): 60-62, Agosto2019.
Article in Spanish | LILACS | ID: biblio-1010315

ABSTRACT

Los defectos óseos secundarios de la tibia en los niños, por procesos infecciosos como la osteomielitis, representan un reto en su tratamiento 1, 2. Históricamente, los defectos en la tibia han sido tratados con un injerto óseo 3. Desde 1983 el uso del injerto autólogo vascularizado con regeneración de los tejidos ha dado resultados favorables 4. La forma más eficaz de estimular la osteogénesis se consigue con un injerto autólogo acompañado de una vascularidad óptima y una conexión con los tejidos blandos.


The bone defects of the tibia in children related to infectious processes such as osteomyelitis, represent a treatment challenge.1,2 Historically, defects in the tibia have been treated with a bone graft.3 Since 1983 use of vascularized autologous graft, with tissue regeneration has met with favorable results.4 The most effective form of osteogenesis is accomplished with an autologous graft accompanied by optimal vascularization and a connection with the soft tissues.


Subject(s)
Humans , Child , Osteomyelitis , Pseudarthrosis , Tibia , Blood Vessels , Tissue Transplantation , Focal Infection
10.
Article in English | WPRIM | ID: wpr-766102

ABSTRACT

PURPOSE: To evaluate the effects of intra-alveolar socket grafting, subepithelial connective tissue grafts, and individualized abutments on peri-implant hard and soft tissue outcomes following immediate implant placement. METHODS: This randomized experimental study employed 5 mongrel dogs, with 4 sites per dog (total of 20 sites). The mesial roots of P3 and P4 were extracted in each hemimandible and immediate dental implants were placed. Each site was randomly assigned to 1 of 4 different treatment groups: standardized healing abutment (control group), alloplastic bone substitute material (BSS) + standardized healing abutment (SA group), BSS + individualized healing abutment (IA group), and BSS + individualized healing abutment + a subepithelial connective tissue graft (IAG group). Clinical, histological, and profilometric analyses were performed. The intergroup differences were calculated using the Bonferroni test, setting statistical significance at P<0.05. RESULTS: Clinically, the control and SA groups demonstrated a coronal shift in the buccal height of the mucosa (0.88±0.48 mm and 0.37±1.1 mm, respectively). The IA and IAG groups exhibited an apical shift of the mucosa (−0.7±1.15 mm and −1.1±0.96 mm, respectively). Histologically, the SA and control groups demonstrated marginal mucosa heights of 4.1±0.28 mm and 4.0±0.53 mm relative to the implant shoulder, respectively. The IA and IAG groups, in contrast, only showed a height of 2.6 mm. In addition, the height of the mucosa in relation to the most coronal buccal bone crest or bone substitute particles was not significantly different among the groups. Volumetrically, the IA group (−0.73±0.46 mm) lost less volume on the buccal side than the control (−0.93±0.44 mm), SA (−0.97±0.73 mm), and IAG (−0.88±0.45 mm) groups. CONCLUSIONS: The control group demonstrated the most favorable change of height of the margo mucosae and the largest dimensions of the peri-implant soft tissues. However, the addition of a bone substitute material and an individualized healing abutment resulted in slightly better preservation of the peri-implant soft tissue contour.


Subject(s)
Animals , Bone Substitutes , Connective Tissue , Dental Implants , Dogs , Mucous Membrane , Shoulder , Tissue Transplantation , Transplants
11.
Rev. latinoam. enferm. (Online) ; 27: e3196, 2019. tab
Article in Portuguese | LILACS, BDENF | ID: biblio-1043060

ABSTRACT

Objetivo identificar os motivos da recusa de córneas. Método estudo transversal, retrospectivo, descritivo e correlacional, composto por 5.560 córneas ópticas. As informações foram extraídas do banco de dados da Central de Notificação, Captação e Doação de Órgãos (CNCDO), bem como de prontuários de doadores. A estatística descritiva foi utilizada para a análise das variáveis categóricas e testes específicos, com nível de significância de 5% para avaliar as associações entre as variáveis. Este estudo atendeu aos aspectos éticos da pesquisa científica. Resultados 60% dos doadores eram do sexo masculino e 40% morreram por problemas circulatórios. Os principais motivos de recusa informados pelas equipes de transplante são a idade do doador e a contagem de células endoteliais. Para cada ano adicionado à idade do doador, há uma redução de 1% na chance de que essa córnea seja usada para transplante, e para cada acréscimo de 100 células por mm2 aumenta as chances de que essa córnea seja usada em 9%. Conclusão a principal causa de recusa na aceitação do tecido corneano está relacionada à idade e à contagem de células endoteliais.


Objective to identify the reasons for refusal of corneas. Method this was a cross-sectional, retrospective, descriptive and correlational study composed of 5,560 optical corneas. The information was taken from the notification, organ procurement and distribution centers database as well as donor records. Descriptive statistics were used for the analysis of categorical variables and specific tests with a significance level of 5% for assessing the associations between variables. This study met the ethical aspects of scientific research. Results 60% of the donors were male and 40% died by circulatory problems. The main reason for refusal as informed by transplant teams is the donor's age and the endothelial cell count. For each year added to the donor's age, there is a 1% decrease in the chance that this cornea will be used for transplantation, and the increase of 100 cells per mm2 increases the chances that this cornea will be used by 9%. Conclusion the main cause of refusal in the acceptance of corneal tissue is related to the age and the endothelial cell count.


Objetivo identificar los motivos para el rechazo de córneas. Método estudio transversal, retrospectivo, descriptivo y correlacional, compuesto por 5.560 córneas ópticas. La información se obtuvo de la bases de datos de Centros de Notificación, Obtención de Órganos y Distribución, así como de los registros de los donantes. Se utilizaron estadísticas descriptivas para analizar las variables categóricas y pruebas específicas con un nivel de significación de 5%, para evaluar las asociaciones entre variables. Este estudio contempla los aspectos éticos de una investigación científica. Resultados el 60% de los donantes eran hombres y el 40% falleció por problemas circulatorios. La principal razón del rechazo, informada por los equipos de trasplante, es la edad del donante y el recuento de las células endoteliales. Por cada año agregado a la edad del donante, existe una disminución de 1% en la probabilidad de que la córnea pueda ser utilizada para trasplante; el aumento de 100 células por mm2 aumenta la posibilidad de que esta córnea será usada por 9%. Conclusión la principal causa de rechazo en la aceptación del tejido corneal está relacionada con la edad y el recuento de células endoteliales.


Subject(s)
Humans , Male , Female , Child, Preschool , Child , Adolescent , Adult , Aged , Aged, 80 and over , Young Adult , Tissue Transplantation/standards , Corneal Transplantation/standards , Cornea/anatomy & histology , Organ Preservation/standards , Quality Control , Time Factors , Tissue Donors/statistics & numerical data , Brazil , Cross-Sectional Studies , Retrospective Studies , Medical Waste Disposal , Tissue and Organ Harvesting/standards , Correlation of Data , Middle Aged
12.
Pesqui. vet. bras ; 38(9): 1818-1823, set. 2018. tab, graf
Article in English | LILACS, VETINDEX | ID: biblio-976511

ABSTRACT

The aim of the present study was to compare tissue repair of skin defects in rabbits submitted to autologous and homologous grafts treated or not with platelet-rich plasma (PRP). We selected nine rabbits and constituted four groups, designated as G1, in which were performed autologous graft treated with PRP; G2, autologous graft only; G3, homologous graft treated with PRP; and G4, homologous graft only. Macroscopic and histomorphometric evaluation was realized. The histomorphometric evaluation was performed by Hematoxylin/Eosin and Masson´s Trichrome staining with quantification of collagen fibers, macrophages, fibroblasts and vessels. The autologous graft treated with PRP showed positive influence on the early stage of the tissue repair process at the macroscopic evaluation, characterized by rosy color and cosmetic appearance. At the histomorphometric evaluation, there was no statistical difference in the number of macrophages and fibroblasts between the treated grafts or not with the PRP, as well as the quantification of vessels and collagen fibers. It can be concluded that PRP promotes a positive influence on the initial phase or "take" of the graft.(AU)


Objetiva-se com o presente estudo comparar a reparação tecidual de defeitos cutâneos em coelhos, submetidos a enxertos autólogos e homólogos, tratados ou não com plasma rico em plaquetas (PRP). Para isso, foram selecionados nove coelhos e constituídos quatro grupos experimentais, designados como G1, no qual foi realizado enxerto autólogo tratado com PRP; G2, enxerto autólogo; G3, enxerto homólogo tratado com PRP; e G4, enxerto homólogo. Foram realizadas avaliações macroscópica e histomorfométrica, por meio das colorações de Hematoxilina/Eosina e Tricômio de Masson, incluindo quantificação de fibras colágenas, contagem de macrófagos, fibroblastos e vasos. O uso do enxerto autólogo com PRP influenciou positivamente na fase inicial do processo de reparação tecidual à avaliação macroscópica, caracterizada por coloração rósea e de aspecto cosmético. À avaliação histomorfométrica, não houve diferença estatística quanto ao número de macrófagos e fibroblastos entre os enxertos tratados ou não com o PRP, bem como quanto às contagens de vasos e a quantificação das fibras colágenas. Conclui-se que o PRP sob a promoveu influência positiva na fase inicial ou de "pega" do enxerto autólogo.(AU)


Subject(s)
Animals , Rabbits , Rabbits/blood , Tissue Transplantation/veterinary
13.
ImplantNewsPerio ; 3(2): 247-253, mar.-abr. 2018.
Article in Portuguese | LILACS, BBO | ID: biblio-883496

ABSTRACT

Este artigo apresenta uma metodologia para tratamento de defeitos alveolares com ausência de uma ou duas paredes ósseas, em regiões de molares, sem o uso de barreiras de Regeneração Óssea Guiada (ROG). A metodologia e seus fundamentos são discutidos e um caso clínico é detalhado para melhor elucidação.


This article presents a special protocol for treatment of alveolar defects in molar regions where one ore two bone walls are absent without using Guided Bone Regeneration (GBR). Its methodological aspects and basic tenets are discussed in addition to a detailed clinica case for better comprehension of this interesting protocol.


Subject(s)
Humans , Bone Regeneration , Bone Transplantation/methods , Clinical Protocols , Dental Implantation, Endosseous , Tissue Transplantation , Tooth Fractures/therapy
14.
ImplantNewsPerio ; 3(2): 315-322, mar.-abr. 2018.
Article in Portuguese | LILACS, BBO | ID: biblio-883517

ABSTRACT

A manipulação adequada dos tecidos moles peri-implantares é de essencial importância para se preservar a saúde em longo prazo, bem como para se obter uma estética favorável após a reabilitação protética dos implantes dentários. Defeitos peri-implantares, como ausência de tecido ceratinizado e perda de espessura tecidual prejudicam o resultado final e a previsibilidade do tratamento, logo o conhecimento sobre intervenções nos tecidos moles para a Implantodontia é fundamental. Este trabalho teve como objetivo realizar uma revisão da literatura abordando a necessidade de se ter volume tecidual e gengiva ceratinizada ao redor dos implantes, e a utilização de enxerto gengival livre e de tecido conjuntivo como as alternativas mais utilizadas para correção destas situações.


Adequate peri-implant soft tissue management is fundamental to preserve its long-term health as well as to obtain a favorable esthetics after dental implant prosthetic rehabilitation. Peri-implant defects, such as the lack of keratinized tissue and the loss of structural support compromise the final outcome and treatment predictability; thus, the knowledge regarding soft tissue intervention in implant dentistry is very important. This paper aims to report a literature review on the need of tissue volume and keratinized gingiva around implants, and the use of free gingival and connective tissue grafts as the most prevalent alternatives to correct those situations.


Subject(s)
Connective Tissue/transplantation , Dental Implantation , Esthetics, Dental , Gingiva , Mouth Rehabilitation , Tissue Transplantation/rehabilitation
15.
ImplantNewsPerio ; 3(1): 58-64, jan.-fev. 2018. ilus
Article in Portuguese | LILACS, BBO | ID: biblio-881608

ABSTRACT

O objetivo deste trabalho foi apresentar o relato de um caso clínico no qual uma paciente de 52 anos, com ausência de tecido queratinizado na região de rebordo do elemento 46, previamente extraído, foi submetida à cirurgia de enxerto gengival livre para criar uma faixa de tecido queratinizado, antes da instalação do implante osseointegrado. Após três meses de cicatrização, foi constatado signifi cativo ganho de tecido queratinizado na região, tornando o sítio mais favorável à reabilitação com implante dentário. Dessa forma, foi seguido o planejamento inicial e instalado um implante na região, que foi reabilitado posteriormente. Diversos trabalhos têm mostrado que o selamento biológico proporcionado por uma adequada faixa de tecido queratinizado ao redor de implantes seria um pré-requisito para a saúde e o sucesso desses implantes no longo prazo. A revisão clínica e radiográfi ca com três anos de acompanhamento mostrou estabilidade do tecido peri-implantar e, consequentemente, o sucesso do tratamento proposto.


The aim of this study was to present a clinical case report where a 52-year-old patient, with absence of keratinized tissue in the ridge region of the previously extracted element 46, received a free gingival graft surgery to create a tissue band before the osseointegrated implant installation. After 3 months of healing, a signifi cant gain of keratinized tissue was observed in the region, making the site more amenable to rehabilitation with a dental implant. In this way, the initial planning was followed and an implant was installed in the region and the restoration delivered afterwards. Several studies have shown that biological sealing provided by a suitable range of keratinized tissue around implants would be a prerequisite for the health and success of these implants in the long run. The clinical and radiographic review with 3 years of follow-up showed stability of the peri-implant tissue and, consequently, the success of the proposed treatment.


Subject(s)
Humans , Male , Female , Middle Aged , Connective Tissue/surgery , Connective Tissue/transplantation , Dental Implantation , Free Tissue Flaps/transplantation , Oral Surgical Procedures , Tissue Transplantation/methods
16.
ImplantNewsPerio ; 3(1): 77-94, jan.-fev. 2018. ilus
Article in Portuguese | LILACS, BBO | ID: biblio-881654

ABSTRACT

Os implantes imediatos têm sido utilizados com bastante frequência como uma forma de tratamento para a substituição de dentes condenados. Entretanto, quando a área a ser tratada pertence à zona estética, muito cuidado deve ser tomado. Nessa região, quando o objetivo é alcançar um peri-implante com estética satisfatória, o profissional deve utilizar técnicas que, associadas ao implante imediato, evitem a formação de um defeito decorrente da remodelação pós-exodontia, ou ainda, utilizar procedimentos de melhoria tecidual nos casos em que os dentes condenados já apresentem defeitos de tecido ósseo e/ou mole ao seu redor. O objetivo deste trabalho é, através da apresentação de um caso clínico de reposição do elemento 41 condenado, com perda óssea severa e defeito mucogengival, demonstrar e discutir uma modalidade de tratamento que utiliza o implante imediato de carga imediata não funcional associado ao enxerto de tecido conjuntivo e preenchimento com osso mineral bovino particulado.


Immediate implants have been used frequently as a treatment choice for the replacement of compromised teeth. However, when the area to be treated belongs to the aesthetic zone, great care must be exercised. In this region, when the objective is to reach a peri-implant with a satisfactory esthetics, the professional must use techniques that, associated to the immediate implant, prevent the formation of a defect due to the bone remodeling after tooth loss or to use procedures of tissue improvement for cases where the compromised teeth already have defects of bone and/or soft tissue around them. The objective of this study is to present a clinical case of replacement at tooth 41 with severe bone loss and mucogingival defect to demonstrate and discuss a treatment modality that uses the immediate implant with non-functional immediate loading associated with the connective tissue graft and particulate, deproteinized bovine bone filling.


Subject(s)
Humans , Male , Adult , Biocompatible Materials , Connective Tissue/transplantation , Dental Implantation/methods , Free Tissue Flaps/transplantation , Immediate Dental Implant Loading , Tissue Transplantation/methods
17.
ImplantNewsPerio ; 3(1): 95-104, jan.-fev. 2018. ilus
Article in Portuguese | LILACS, BBO | ID: biblio-881694

ABSTRACT

O sucesso de uma reabilitação com implantes depende não só de sua funcionalidade, mas também de uma estética que abranja desde a coroa sobre o implante ao tecido mole que o envolve, visando à manutenção das características teciduais de um dente natural. A cirurgia plástica peri-implantar passou a ser largamente utilizada para correções de defeitos ósseos e teciduais em áreas que sofreram remodelação tecidual extensa após a extração. Apesar da grande variedade de técnicas que podem ser utilizadas, existem limitações em relação à previsibilidade do resultado. No relato de caso apresentado, foram utilizadas três técnicas de cirurgia plástica para o ganho tecidual e a melhora estética do defeito de crista apresentado entre implantes anteriores.


The success of implant rehabilitation depends not only on its functionality, but also on an aesthetic that involves the implant crown and the soft tissue that surrounds it, aiming to maintain the tissue characteristics of a natural tooth. Perimplantar plastic surgery became widely used for corrections of bone and tissue defects in areas that underwent extensive tissue remodeling after extraction. Despite the wide range of techniques that can be used, there are limitations to the predictability of the outcome. In the case report presented, three techniques of plastic surgery were used for tissue gain and esthetic improvement of the crestal defect presented between adjacent implants in the anterior region.


Subject(s)
Humans , Male , Middle Aged , Dental Implantation/methods , Esthetics, Dental , Free Tissue Flaps , Oral Surgical Procedures , Surgery, Oral/methods , Tissue Transplantation/methods
18.
ImplantNewsPerio ; 3(1): 111-117, jan.-fev. 2018.
Article in Portuguese | LILACS, BBO | ID: biblio-881703

ABSTRACT

A doença periodontal causa uma perda na estrutura de suporte dos elementos dentários. Como consequência, ocorre o aparecimento de sequelas provenientes dessa doença. Por conta disso foram desenvolvidos materiais com a fi nalidade de regeneração tecidual na estrutura de suporte, para que houvesse maior sobrevida desses elementos, aumento na quantidade de gengiva inserida e melhor otimização estética para os pacientes. Dentre os inúmeros materiais, temos a Matriz Colágena Porcina, que simplesmente é uma membrana obtida a partir de suínos, sendo que esta passa por uma cadeia de procedimentos, com a fi nalidade de minimizar e/ou eliminar qualquer tipo de interação alergênica no ser humano. A sua utilização é dada principalmente no aumento de tecidos moles ao redor de dentes afetados com a doença periodontal e em implantes osseointegrados, trazendo como principal vantagem a redução de morbidade do paciente, evitando, assim, a necessidade de um segundo sítio cirúrgico.


Periodontal disease results in the loss of structural support on dental elements. As such, sequels can be seen in the mouth. For this, materials were develop for tissue regeneration in order to increase the amount of attached gingiva and to optimize patient esthetics. The porcine collagen matrix is a product were the collagen undergoes a series of several treatments to minimize any type of allergic reaction to the human body. For example, it can be used for soft tissue augmentation around affected teeth and dental implants. Also, the porcine collagen matrix can reduce patient morbidity because it avoids autologous soft tissue harvesting.


Subject(s)
Humans , Biocompatible Materials , Gingival Recession/therapy , Guided Tissue Regeneration, Periodontal , Heterografts , Tissue Transplantation/methods , Transplantation, Heterologous
19.
ImplantNewsPerio ; 3(1): 148-157, jan.-fev. 2018. ilus
Article in Portuguese | LILACS, BBO | ID: biblio-881732

ABSTRACT

A recessão gengival é uma queixa relativamente comum entre os pacientes quando procuram o cirurgião-dentista, e os motivos desse incômodo são sensibilidade e estética. Os autores relatam que o tratamento de recessões gengivais posteriores bilaterais são realizados a partir do transplante do tecido conjuntivo subepitelial. Já a técnica operatória utilizada nesse caso, para o posicionamento do tecido conjuntivo, foi a de Langer, com reposicionamento coronário do retalho. Houve um aumento considerável com relação ao recobrimento radicular, sugerindo um processo de reparação da recessão gengival bilateral, com a interposição do tecido conjuntivo na área receptora. Em relação à praticidade, a técnica de Langer mostra-se mais fácil de ser realizada com relação ao aspecto estético, recobrimento, ganho em altura e espessura. O objetivo desse trabalho é relatar um caso clínico de resolução estética para recessão gengival. A terapia inicial do presente caso consistiu em instruções de higiene oral acompanhado de raspagem dos dentes nos 30 dias anteriores à cirurgia. Os procedimentos cirúrgicos foram feitos seguindo técnica consagrada pela ciência. O enxerto de tecido do palato foi transplantado para a região de recessão, a fim de recobrir as áreas de exposição radicular. O paciente recebeu instruções de cuidados de higiene. Após 14 dias do pós-cirúrgico, realizou-se a remoção dos pontos e uma instrução para higiene permanente do local. O resultado clínico foi uma boa estética para o paciente. Geralmente não possui recidiva mediante cuidados no controle de higiene oral e hábitos.


Gingival recession is a relatively common complaint for patients seeking treatment due to sensitivity and esthetics. The authors report that the treatment of bilateral posterior gingival recessions is performed using the subepithelial connective tissue grafting. The operative technique used in this case was the Langer's method with coronary flap repositioning. There was a considerable increase regarding root coverage, suggesting repair process of the bilateral gingival recession with the interposition of connective tissue in the recipient area. In relation to clinical aspects, the Langer's technique is easier to be performed in relation to the esthetic aspect, coverage, and gains in height and thickness. The purpose of this paper is to report a clinical case to solve the gingival recession. The initial therapy consisted of oral hygiene instructions and root planning 30 days prior to surgery. Afterwards, the surgical procedures were performed accordingly. The graft was harvested from the palate and transplanted to the recession area to cover the areas of root exposure. After 14 days, sutures were removed and oral hygiene instruction was recommended. The clinical results were excellent in terms of esthetics. Generally, no relapse was observed after good oral hygiene and habits.


Subject(s)
Humans , Female , Adult , Connective Tissue/surgery , Connective Tissue/transplantation , Esthetics, Dental , Gingival Recession/therapy , Oral Surgical Procedures , Tissue Transplantation/methods
20.
Article in English | WPRIM | ID: wpr-715710

ABSTRACT

Adolescent and young adult (AYA) patients are generally defined as being from 15 to 39 years old. For preservation of fertility in AYA cancer patients, the best-known guideline in this field was released by the American Society of Clinical Oncology (ASCO) in 2006. However, the ASCO guideline is not necessarily applicable to Japanese cancer patients. The Japan Society for Fertility Preservation (JSFP) was formed in 2012, and a system and guideline for fertility preservation in Japanese AYA cancer patients plus children was released in July 2017. According to this guideline, patients should receive psychological and social support from health care providers such as doctors, nurses, psychologists, pharmacists, and social workers. In 2013, the American Society for Reproductive Medicine stated that freezing oocytes is a method that has passed beyond the research stage. However, freezing ovarian tissue is still a research procedure. While slow freezing of ovarian tissue is generally performed, rapid freezing (vitrification) is more popular in Japan. We have developed a new closed technique for ovarian tissue cryopreservation. It has been suggested that optical coherence tomography might be applied clinically to measure the true ovarian reserve and localize follicles in patients undergoing ovarian tissue transplantation. Combining gonadotropin-releasing hormone agonist therapy with anticancer agents might be useful for ovarian protection and it is expected that discussion of such combined treatment will continue in the future. This article outlines practical methods of fertility preservation using assisted reproductive techniques for AYA cancer patients in Japan.


Subject(s)
Adolescent , Antineoplastic Agents , Asian Continental Ancestry Group , Child , Cryopreservation , Fertility Preservation , Fertility , Freezing , Gonadotropin-Releasing Hormone , Health Personnel , Humans , Japan , Medical Oncology , Methods , Oocytes , Ovarian Reserve , Pharmacists , Psychology , Reproductive Medicine , Reproductive Techniques, Assisted , Social Work , Social Workers , Tissue Transplantation , Tomography, Optical Coherence , Transplants , Vitrification , Young Adult
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