ABSTRACT
Objective: To evaluate the effect of polidocanol foam sclerotherapy in patients with venous ulcers (VU) undergoing clinical treatment with elastocompression. Method: This will be a randomized, prospective, single-center, exploratory clinical trial with two parallel groups and 1:1 allocation. Participants aged 18-80 years with active VU and vascular Doppler ultrasound findings indicating chronic superficial venous insufficiency in both sexes will be included. Participants will be randomized into two groups: the Clinical group (undergoing conservative treatment with elastocompression) and Foam group (undergoing treatment of varicose veins with polidocanol foam associated with elastocompression). Thirty-four patients will be selected for each group. Participants in the Foam group will undergo superficial vein sclerotherapy using the Tessari technique, with the aid of ultrasound. Patients will be reassessed 30, 90, and 180 days after the intervention. The primary outcome will be lesion healing within 180 days. The secondary outcomes will be the VU healing time, rate of lesion area reduction, side effects, pain, quality of life (QOL) using the EQ-5D, and the Venous Clinical Severity Score. The data will be subjected to inferential tests and Kaplan-Meier survival analysis, assuming a significance level of 5%.
Subject(s)
Humans , Adult , Middle Aged , Aged , Aged, 80 and over , Varicose Ulcer , Varicose Veins , Venous Insufficiency , Sclerotherapy , Ultrasonography, Doppler , Polidocanol , Patients , Quality of Life , Therapeutics , Veins , Volition , Survival Analysis , Insemination, Artificial, Heterologous , MethodsABSTRACT
The article discusses mitral regurgitation (MI), a heart condition characterized by incomplete closure of the mitral valve, which causes regurgitation of blood into the left atrium. This problem can be due to various etiologies, such as degenerative or ischemic diseases, and is mainly evaluated with Doppler echocardiography, which makes it possible to measure the severity of regurgitation and study functional parameters of the heart. We present a clinical case of a 69-year-old man who was evaluated for chronic dyspnea. Initial echocardiographic studies suggested possible severe aortic stenosis, but detailed analysis revealed that the observed discharge was caused by a regurgitating stream of severe mitral regurgitation secondary to mitral vela prolapse. This simulated an elevated gradient in the aortic valve. The correct diagnosis allowed a mitral valve replacement with a favorable evolution. The coexistence of mitral regurgitation and other valvular diseases may complicate the diagnosis due to hemodynamic interactions. The use of advanced imaging techniques, such as transesophageal echocardiography, is critical to differentiate between conditions, ensure an accurate diagnosis, and guide appropriate treatment.
El artículo trata sobre la insuficiencia mitral (IM), un trastorno cardíaco caracterizado por el cierre incompleto de la válvula mitral, que causa regurgitación de sangre hacia la aurícula izquierda. Este problema puede deberse a varias etiologías, como enfermedades degenerativas o isquémicas, y se evalúa principalmente con ecocardiografía Doppler, que permite medir la severidad de la regurgitación y estudiar parámetros funcionales del corazón. Se presenta un caso clínico de un hombre de 69 años que fue evaluado por disnea crónica. Los estudios ecocardiográficos iniciales sugirieron una posible estenosis aórtica severa, pero el análisis detallado reveló que el flujo observado era causado por un chorro regurgitante de una insuficiencia mitral severa secundaria a prolapso de un velo mitral. Esto simulaba un gradiente elevado en la válvula aórtica. El diagnóstico correcto permitió realizar un reemplazo de la válvula mitral con evolución favorable. La coexistencia de insuficiencia mitral y otras valvulopatías puede complicar el diagnóstico debido a interacciones hemodinámicas. El uso de técnicas avanzadas de imagen, como la ecocardiografía transesofágica, es fundamental para diferenciar entre condiciones, garantizar un diagnóstico preciso y guiar el tratamiento adecuado.
Subject(s)
Humans , Male , Aged , Heart Failure/physiopathology , Mitral Valve/physiopathology , Mitral Valve Insufficiency/physiopathology , Aortic Valve/surgery , Aortic Valve Stenosis/surgery , Aortic Valve Stenosis/diagnosis , Aortic Valve Stenosis/physiopathology , Aortic Valve Stenosis/therapy , Echocardiography, Transesophageal , Ultrasonography, Doppler , Mitral Valve/diagnostic imaging , Mitral Valve Insufficiency/etiology , Mitral Valve Insufficiency/therapy , Mitral Valve Insufficiency/diagnostic imagingABSTRACT
Introducción: El ultrasonido Doppler es una herramienta muy útil para medir el flujo de las arterias uterinas en el primero y segundo trimestre del embarazo. Objetivo: La relación existente entre la flujometría Doppler patológica y la predicción de preeclampsia. Métodos: Se realizó una investigación de cohorte, observacional y analítica prospectiva. De 113 embarazadas con Doppler patológico en el primer trimestre y de seguimientos, se seleccionó una muestra de n = 65 correspondiente a todas las gestantes sanas que culminaron su parto y puerperio. Se analizaron variables como edad, tiempo gestación, peso fetal, tipo o vía del parto, así como la validez como predictor de preeclampsia. Los datos se procesaron para su análisis utilizando la estadística descriptiva. Las variables cualitativas se resumieron según frecuencias absolutas y relativas porcentuales, se calculó la media de la edad y su desviación estándar. Resultados: La relación entre Doppler patológico y preeclampsia fue de 15,3 por ciento y se relacionó más con Doppler a las 24 semanas y de la arteria uterina, predominaron las edades de 20-34 años, edad promedio = 27,2 años, coincidió con mayor porcentaje de preeclampsia, el 9,2 por ciento con preeclampsia requirió de cesárea, predominaron los embarazos a término y el recién nacido con peso mayor de 2500 gramos, la morbilidad más asociada fue la anemia, seguido de crecimiento uterino retardado Conclusiones: El uso del Doppler en esta investigación no demostró su valor predictivo en el pesquizaje de la preeclampsia(AU)
Introduction: Doppler ultrasound is a very useful tool for measuring uterine artery flow in the first and second quarters of pregnancy. Objective: The relationship between pathological Doppler flowmetry and the prediction of preeclampsia. Methods: A prospective, observational and analytical cohort study was performed. From 113 pregnant women with pathological Doppler in the first quarters and follow-up, a sample of 65 was selected, corresponding to all healthy pregnant women who completed their delivery and puerperium. Variables such as age, gestation time, fetal weight, type or route of delivery, as well as validity as a predictor of preeclampsia, were analyzed. The data were processed for analysis using descriptive statistics. Qualitative variables were summarized according to absolute and relative percentage frequencies, while mean age and its standard deviation were calculated. Results: The relationship between pathologic Doppler and preeclampsia was 15.3 percent. It was more related to Doppler at 24 weeks and uterine artery Doppler. Ages 20-34 years predominated. The mean age (27.2 years) coincided with a higher percentage of preeclampsia. The 9.2 percent with preeclampsia required cesarean section. There was a predominance of term pregnancies and newborns weighing more than 2500 grams. The most associated morbidity was anemia, followed by delayed uterine growth. Conclusions: The use of Doppler in this research did not demonstrate its predictive value in the screening for preeclampsia(AU)
Subject(s)
Humans , Female , Pregnancy , Adolescent , Adult , Pre-Eclampsia/prevention & control , Maternal Mortality/trends , Laser-Doppler Flowmetry/methods , Ultrasonography, Doppler/methods , Prospective Studies , Observational StudyABSTRACT
Introducción: La oclusión de la arteria central de la retina o de alguna de sus ramas constituye un accidente vascular agudo que amenaza la visión del paciente. Esta es la causa más frecuente de pérdida brusca e indolora de la visión. Objetivo: Presentar un caso de oclusión de la arteria central de la retina diagnosticado mediante ultrasonido Doppler. Métodos: Se consideró una combinación de métodos clínicos e imagenológicos. Presentación del caso: Se presenta un paciente masculino, de raza blanca y 55 años que acudió a Consulta Externa del Servicio De Oftalmología del Hospital Clínico Quirúrgico "Lucia Iñiguez Landín", de Holguín. Refirió pérdida visual súbita en el ojo izquierdo, motivo por el cual fue tratado mediante ultrasonido Doppler y puesto bajo seguimiento. Conclusiones: Un acertado enfoque diagnóstico ha sido siempre un reto intelectual fascinante para los médicos, y una fuente inagotable de satisfacciones en su vida profesional, siempre y cuando se dominen sus bases y procedimientos, sirva esto como singularidad y novedad de la obra que se presenta(AU)
Introduction: Occlusion of the central retinal artery or any of its branches is an acute vascular accident that threatens the patient's vision. This is the most frequent cause of sudden and painless loss of vision. Objective: To present a case of central retinal artery occlusion diagnosed by Doppler ultrasound. Methods: A combination of clinical and imaging methods was considered. Case presentation: The case is presented of a 55-year-old white male patient, who attended the outpatient department of the ophthalmology service at Hospital Clínico Quirúrgico Lucia Íñiguez Landín, in Holguín. He reported sudden loss of vision in the left eye, for which he was treated by Doppler ultrasound and received follow-up. Conclusions: An accurate diagnostic approach has always been a fascinating intellectual challenge for physicians, as well as an inexhaustible source of satisfactions in their professional life, as long as its bases and procedures are mastered; let this serve as singularity and novelty of the presented work(AU)
Subject(s)
Humans , Female , Middle Aged , Retinal Artery Occlusion , Ultrasonography, Doppler , Outpatients , AftercareABSTRACT
Introducción: La enfermedad aterotrombótica de las arterias cérvico-cerebrales representa el 40 % de las causas de infarto cerebral. Objetivo: Determinar la asociación entre el tamaño del infarto cerebral aterotrombótico de territorio anterior y la aterosclerosis carotídea bilateral. Métodos: Se realizó un estudio observacional y transversal a 63 pacientes que acudieron al hospital "Dr. Carlos J. Finlay" con diagnóstico de ictus aterotrombótico reciente de territorio carotídeo en el período comprendido entre 2011 y 2013, a quienes se les realizó tomografía de cráneo y eco-Doppler carotídeo. Resultados: El tamaño del infarto presentó asociación estadísticamente significativa (p = 0,034) con la estenosis predominante de la placa de ateroma en el eje carotídeo homolateral. La estabilidad (p = 0,039) y la cantidad de placas (p = 0,017) del eje homolateral tuvo significación estadística tanto con la estenosis homolateral como con el infarto grande. En el eje contralateral con la estabilidad (p = 0,000), el contorno (p = 0,029) y la cantidad de placas (p = 0,008) pasó igual. Conclusiones: Se relacionan con el infarto cerebral grande y la presencia de estenosis en los ejes carotídeos, el contorno de la placa de ateroma del eje contralateral, la cantidad de placas de ateroma y la estabilidad de ambos ejes. La estenosis significativa bilateral se asocia a la cantidad de placas de ateroma en ambos ejes carotídeos, lo cual es indicativo de que traen consigo una notable repercusión en la hemodinámica cerebral y, consecuentemente, en el tamaño del infarto(AU)
Introduction: Atherothrombotic disease of the cerebrospinal arteries accounts for 40% of the causes of cerebral infarction. Objective: To determine the association between the size of atherothrombotic stroke of the anterior territory and bilateral carotid atherosclerosis. Methods: An observational and cross-sectional study was carried out in 63 patients who attended Dr. Carlos J. Finlay Hospital with a diagnosis of recent atherothrombotic stroke of the carotid territory in the period between 2011 and 2013, who underwent cranial tomography and carotid Doppler ultrasound. Results: Infarction size presented statistically significant association (p = 0.034) with predominant atheroma plaque stenosis in the homolateral carotid axis. The stability (p = 0.039) and number of plaques (p = 0.017) of the homolateral axis had a statistical significance with both homolateral stenosis and large infarction. In the contralateral axis, the same phenomenon occurred with stability (p = 0.000), contour (p = 0.029) and number of plaques (p = 0.008). Conclusions: The contralateral axis atheroma plaque contour, the number of atheroma plaques and the stability of both axes are associated with large cerebral infarction and the presence of carotid axis stenosis. Bilateral significant stenosis is associated with the number of atheroma plaques in both carotid axes, a phenomenon indicative of the fact that they bring about a notable impact on cerebral hemodynamics and, consequently, on infarction size(AU)
Subject(s)
Humans , Carotid Artery Diseases , Ultrasonography, Doppler , Stroke/etiology , Atherosclerosis , Cross-Sectional StudiesABSTRACT
Introducción: El síndrome de Paget-Schroetter (SPS) es una trombosis venosa profunda primaria del complejo venoso subclavio-axilar que ocurre después del uso repetitivo y extenuante de los hombros y los brazos. Muestra una incidencia de 1 por 100 000 personas al año. Se informa con mayor frecuencia en atletas jóvenes. Objetivo: Presentar un caso inusual de síndrome de Paget-Schroetter en un individuo joven no deportista. Caso clínico: Varón militar activo de 24 años de edad, sin antecedentes patológicos personales, que ingresó con inflamación del miembro superior izquierdo de 24 horas de evolución. Presentó una trombosis de la vena cefálica izquierda después de un esfuerzo físico de carga y descarga. Tras descartar trastornos secundarios de hipercoagulabilidad se le diagnosticó un SPS. Se le informó de la opción de intervención quirúrgica, pero la rechazó. El diagnóstico fue confirmado con ecografía Doppler y tratado con anticoagulación endovenosa al inicio y luego por vía oral durante 6 meses. Durante el seguimiento no se evidenció trombosis crónica de la vena cefálica izquierda ni formación de intervalo de colaterales vasculares. Conclusiones: El SPS es una condición clínica que necesita un alto índice de sospecha y un diagnóstico oportuno, por tanto, los médicos deben estar atentos a esta rara entidad para su reconocimiento temprano y derivación oportuna a cirugía vascular(AU)
Introduction: Paget-Schroetter syndrome (PSS) is a primary deep vein thrombosis of the subclavian-axillary venous complex that occurs after repetitive and strenuous use of the shoulders and arms. It shows an incidence of 1 per 100,000 people per year. It is reported more frequently in young athletes. Objective: To present an unusual case of Paget-Schroetter syndrome in a young non-athlete individual. Clinical case: 24-year-old active military man with no personal pathological history is presented, who was admitted with inflammation of the left upper limb of 24 hours of evolution. He presented a thrombosis of the left cephalic vein after a physical effort of loading and unloading. After ruling out secondary hypercoagulability disorders, he was diagnosed with SPS. He was informed of the option of surgical intervention, but he declined it. The diagnosis was confirmed with Doppler ultrasound and treated with intravenous anticoagulation at the beginning, and then orally for 6 months. During the follow-up of the patient, there was no evidence of chronic thrombosis of the left cephalic vein or interval formation of vascular collaterals. Conclusions: SPS is a clinical condition that requires a high index of suspicion and prompt diagnosis, therefore, physicians must be attentive to this rare entity for early recognition and timely referral to vascular surgery(AU)
Subject(s)
Humans , Male , Adult , Ultrasonography, Doppler/methods , Physical Exertion , Upper Extremity Deep Vein Thrombosis/diagnostic imaging , Heparin/administration & dosage , Military Personnel , Anticoagulants/therapeutic useABSTRACT
Objetivo: Determinar los hallazgos por ecografía Doppler arterial oftálmica en pacientes con enfermedad renal crónica avanzada. Métodos: Se efectuó un estudio observacional descriptivo y transversal con 212 órbitas de 106 pacientes con enfermedad renal crónica avanzada (estadios 4 y 5 en tratamiento dialítico). Por interrogatorio y examen físico se identificaron los factores de riesgo aterosclerótico. Además, se realizó ultrasonido orbitario y Doppler carotídeo, y solo en caso de resultar normales, se procedió a evaluar mediante ecografía Doppler las arterias oftálmicas. Resultados: Predominaron los pacientes mayores de 50 años, el sexo masculino, el color mestizo de piel y los normopesos; mientras que la hipertensión arterial, el tabaquismo y la diabetes mellitus tipo 2 fueron los factores de riesgo aterosclerótico mayoritarios. En todos los enfermos renales crónicos se demostró un incremento de la velocidad del flujo y de la resistencia vascular a nivel de las arterias oftálmicas, en tanto los casos con hipertensión arterial y diabetes mellitus tipo 2, así como los hipertensos exclusivos, mostraron los valores hemodinámicos más elevados. Conclusiones: La evaluación de las arterias oftálmicas mediante ecografía Doppler permite hacer un estudio y seguimiento más integral de los pacientes con enfermedad renal crónica avanzada(AU)
Objective: To determine ophthalmic arterial Doppler ultrasound findings in patients with advanced chronic kidney disease. Methods: A descriptive and cross-sectional observational study was carried out with 212 orbits of 106 patients with advanced chronic kidney disease (stages 4 and 5 in dialysis treatment). Atherosclerotic risk factors were identified by interrogation and physical examination. In addition, orbital ultrasound and carotid Doppler were performed, and only if they were normal, the ophthalmic arteries were evaluated by Doppler ultrasound. Results: Patients older than 50 years, male sex, mestizo skin color and normal weight predominated, while arterial hypertension, smoking and type 2 diabetes mellitus were the main atherosclerotic risk factors. An increase in flow velocity and vascular resistance at the level of the ophthalmic arteries was demonstrated in all chronic renal patients, while cases with arterial hypertension and type 2 diabetes mellitus, as well as exclusive hypertensives, showed the highest hemodynamic values. Conclusions: The evaluation of the ophthalmic arteries by Doppler ultrasound allows a more comprehensive study and follow-up of patients with advanced chronic kidney disease(AU)
Subject(s)
Humans , Male , Middle Aged , Ultrasonography, Doppler/methods , Epidemiology, Descriptive , Cross-Sectional Studies , Observational Studies as TopicABSTRACT
Introducción: Los paragangliomas de cuerpo carotideo son tumores neuroendocrinos hipervascularizados raros. Aunque su presentación clínica es frecuentemente asintomática, con el transcurso de los años puede manifestarse como tumores cervicales con o sin déficit neurológico. Objetivo: Presentar el caso de una paciente con tumoración cervical pulsátil de 10 años de evolución que requirió tratamiento quirúrgico. Presentación de caso: Mujer de 42 años procedente del Cusco, Perú, sin antecedentes médicos ni personales de importancia. La paciente acude al Servicio de Cirugía de Cabeza y Cuello por presentar tumoración cervical pulsátil de crecimiento lento progresivo, cefalea y disfagia. Tras realizar ultrasonografía Doppler y angiotomografía se pesquisa tumor cervical derecho hipervascularizado a nivel de la bifurcación de arteria carótida común. Se propone tratamiento quirúrgico de tumoración cervical con resultado anatomopatológico de paraganglioma de cuerpo carotideo. Tuvo una evolución posquirúrgica favorable sin evidencia de recurrencias en el seguimiento. Conclusión: El paraganglioma del cuerpo carotideo es una tumoración rara, de presentación clínica frecuentemente asintomática. Una evaluación minuciosa clínica e imagenológica permiten un diagnóstico adecuado para una planificación quirúrgica óptima(AU)
Introduction: Carotid body paragangliomas are rare hypervascularized neuroendocrine tumors. Although their clinical presentation is frequently asymptomatic, they may manifest as cervical tumors with or without neurological deficit over the years. Objective: To present the case of a patient with a pulsatile cervical tumor of 10 years' evolution that required surgical treatment. Case presentation: A 42-year-old woman from Cusco, Peru, with no medical or personal history of importance. The patient came to the head and neck surgery service for presenting a pulsatile cervical tumor with slow progressive growth, as well as headache and dysphagia. After performing Doppler ultrasonography and angiotomography, a hypervascularized right cervical tumor was observed at the level of the common carotid artery bifurcation. Surgical treatment of the cervical tumor was proposed, whose anatomopathological result was carotid body paraganglioma. Postoperative evolution was favorable, with no evidence of relapses during follow-up. Conclusion: Carotid body paraganglioma is a rare tumor of frequently asymptomatic clinical presentation. A thorough clinical and imaging-based assessment allows an adequate diagnosis for optimal surgical planning(AU)
Subject(s)
Humans , Female , Adult , Paraganglioma/diagnostic imaging , Carotid Body Tumor/surgery , Ultrasonography, Doppler/methodsABSTRACT
Background@#Gestational trophoblastic neoplasia (GTN) presents as vascular mass of varying morphology on ultrasound and confirmed through quantitative serum β subunit human chorionic gonadotrophin (β‑hCG). In regions with limited access to β‑hCG, ultrasound plays a crucial role in the initial diagnosis for timely management.@*Objectives@#This study aimed to investigate the associations between ultrasound vascular morphologic features, serum β‑hCG levels, and histopathology in GTN cases.@*Methodology@#A cross‑sectional review was conducted on 113 cases with ultrasound impression of GTN over an 8‑year period. The patient data were extracted from case records, and ultrasound images were categorized based on the distinct features. Associations with β‑hCG levels and histopathology were analyzed using the Chi‑square test and Mann–Whitney U‑test. Statistical significance was set at P < 0.05.@*Results@#A significant association was observed between ultrasound category and serum β‑hCG (P < 0.0001). The compact and diffuse types were more prevalent with β‑hCG levels between 104 to <105 mIU/mL, while the lacunar type was common among patients with ≥105 mIU/mL. However, there was no significant association between ultrasound categories and mean β‑hCG levels. Regarding histopathology, the lacunar type was more common in invasive moles, whereas the compact and diffuse types tended to be seen with choriocarcinoma, although these were not statistically significant (P = 0.182).@*Conclusions@#Morphologic types of GTN by gray scale and Doppler ultrasound vary across the different levels of serum β‑hCG and may suggest the histopathological diagnosis. This study provides valuable insights into the ultrasonographic characteristics of GTN, which can aid in its diagnosis and management.
Subject(s)
Gestational Trophoblastic Disease , Ultrasonography, DopplerABSTRACT
Background@#Pelvic arteriovenous malformations (AVMs) are rare but carries life-threatening consequences.@*Case Report@#A 47-year-old multipara who had previously undergone four cesarean sections came for re-evaluation of a malignant ovarian new growth. She was asymptomatic. Repeat ultrasound revealed normal ovaries, and a cystic structure at the left adnexa with abundant mixing of colors, turbulent flow and pulsative waveforms on spectral Doppler. It arises from serpentine tubular structures from the uterine isthmus. Uterine artery aneurysm was considered. Magnetic resonance angiography confirmed the findings of aneurysm and pelvic arteriovenous malformation. The patient underwent a hysterectomy with ligation and excision of aneurysm. Histopathologic findings showed pelvic AVM and a true aneurysm of the uterine artery.@*Conclusion@#Ultrasound with color Doppler is a low-cost and readily available tool for gynecologists for the diagnosis and management of pelvic AVM.
Subject(s)
Ultrasonography, DopplerABSTRACT
ABSTRACT BACKGROUND: Liver transplantation represents the best therapeutic modality in end-stage chronic liver disease, severe acute hepatitis, and selected cases of liver tumors. AIMS: To describe a double retransplant in a male patient diagnosed with Crohn's disease and complicated with primary sclerosing cholangitis, severe portal hypertension, and cholangiocarcinoma diagnosed in the transplanted liver. METHODS: A 48-year-old male patient diagnosed with Crohn's disease 25 years ago, complicated with primary sclerosing cholangitis and severe portal hypertension. He underwent a liver transplantation in 2018 due to secondary biliary cirrhosis. In 2021, a primary sclerosing cholangitis recurrence was diagnosed and a liver retransplantation was indicated. Recipient's hepatectomy was very difficult by reason of complex portal vein thrombosis requiring extensive thromboendovenectomy. Intraoperative ultrasound with liver doppler evaluation was performed. Two suspicious nodules were incidentally diagnosed in the donor's liver and immediately removed for anatomopathological evaluation. RESULTS: After pathological confirmation of carcinoma, probable cholangiocarcinoma, at frozen section, the patient was re-listed as national priority and a new liver transplantation was performed within 24 hours. The patient was discharged after 2 weeks. CONCLUSIONS: The screening for neoplasms in donated organs should be part of our strict daily diagnostic arsenal. Moreover, we argue that, for the benefit of an adequate diagnosis and the feasibility of a safer procedure, the adoption of imaging tests routine for the liver donor is essential, allowing a reduction of the costs and some potential risks of liver transplant procedure.
RESUMO RACIONAL: O transplante de fígado representa a melhor modalidade terapêutica na doença hepática crônica terminal, hepatite aguda grave e casos selecionados de tumores hepáticos. OBJETIVOS: Descrever um retransplante duplo em paciente do sexo masculino, diagnosticado com doença de Crohn e complicado com colangite esclerosante primária, hipertensão portal grave e colangiocarcinoma diagnosticado no fígado transplantado. MÉTODOS: Paciente do sexo masculino, 48 anos, diagnosticado com doença de Crohn há 25 anos e complicado com colangite esclerosante primária e hipertensão portal grave. Foi submetido a um transplante de fígado em 2018 devido a cirrose biliar secundária. Em 2021, foi diagnosticada recidiva de colangite esclerosante primária e indicado retransplante hepático. A hepatectomia do receptor foi de alta complexidade devido à trombose complexa da veia porta, exigindo extensa tromboendovenectomia. Foi realizada ultrassonografia intraoperatória com doppler hepático. Dois nódulos suspeitos foram diagnosticados incidentalmente no fígado do doador e imediatamente removidos para avaliação anatomopatológica. RESULTADOS: Após confirmação patológica de carcinoma, provável colangiocarcinoma, pela congelação, o paciente foi relistado como prioridade nacional, e novo transplante hepático foi realizado em 24 horas. O paciente teve alta após 2 semanas. CONCLUSÕES: O rastreamento de neoplasias em órgãos doados deve fazer parte de nosso estrito arsenal diagnóstico diário. Além disso, defendemos que, em benefício de um diagnóstico correto e da viabilidade de um procedimento mais seguro, a adoção de uma rotina de exames de imagem é essencial em doadores hepáticos, permitindo a redução dos custos e alguns riscos potenciais do procedimento de transplante hepático.
Subject(s)
Humans , Male , Middle Aged , Bile Duct Neoplasms/surgery , Cholangitis, Sclerosing/surgery , Crohn Disease/complications , Liver Transplantation , Cholangiocarcinoma/surgery , Cholangiocarcinoma/diagnostic imaging , Reoperation , Bile Duct Neoplasms/pathology , Bile Duct Neoplasms/diagnostic imaging , Bile Ducts, Intrahepatic , Cholangitis, Sclerosing/etiology , Cholangiocarcinoma/pathology , Ultrasonography, Doppler , Living Donors , Hypertension, Portal/etiologyABSTRACT
Abstract Objectives: to evaluate the relationship between the ductus venosus (DV) and the variables of fetal growth in the first trimester in a Colombian pregnant population. Methods: a descriptive cross-sectional study was carried out with secondary data obtained from a multicenter study.526 patients were included between weeks 11 and 14 for gestational ultrasound follow-up attended in three health care institutions in Bogotá, Colombia, between May 2014 and October 2018. A bivariate descriptive analysis was carried out where the relationship between the characteristics of the DV in the first trimester and ultrasound findings. Results: the flow wave of the DV in the first trimester was normal in the entire sample, with a pulsatility index of the ductus venosus (DVPI) of 0.96±0.18. In addition, a negative correlation was found between the crown-rump length (CRL) and the DVPI (p<0.05). Conclusion: there is a relationship between the DVPI regarding the CRL, indicating an interest in this early marker in relation to fetal growth alterations; however, more studies are required to determine the usefulness of this variable with respect to fetal growth.
Resumen Objetivos: evaluar la relación entre el ductus venoso (DV) y las variables del crecimiento fetal en primer trimestre en una población de gestantes colombianas. Métodos: se realizó un estudio transversal descriptivo con datos secundarios obtenidos de un estudio multicéntrico. Se incluyeron 526 pacientes entre las semanas 11 a 14 para seguimiento ecográfico gestacional atendidas en tres instituciones prestadoras de salud en Bogotá, Colombia, entre mayo del 2014 y octubre del 2018. Se realizó un análisis descriptivo bivariado donde se evaluó la relación entre las características del DV en primer trimestre y los hallazgos ecográficos. Resultados: la onda de flujo del DV en primer trimestre fue normal en la totalidad de la muestra, con un índice medio de pulsatilidad del ductus venoso (IPDV) de 0,96±0.18. Se encontró una correlación negativa entre la longitud cefalocaudal (LCC) y el IPDV (p<0.05). Conclusión: existe una relación entre el IPDV respecto a la LCC, señalando un interés de este marcador temprano en relación con las alteraciones del crecimiento fetal, sin embargo, se requieren más estudios para determinar la utilidad entre esta variable respecto al crecimiento fetal
Subject(s)
Humans , Female , Pregnancy , Placental Insufficiency , Pregnancy Trimester, First , Ultrasonography, Doppler/methods , Pregnancy, High-Risk , Crown-Rump Length , Fetal Growth Retardation/diagnostic imaging , Hemodynamic Monitoring , Cross-Sectional Studies , ColombiaABSTRACT
Na gestação várias mudanças pelas quais as mulheres passam são capazes de intervir no seu estado de saúde. Estudos relatam que a incapacidade do corpo de algumas gestantes de acomodarem o crescimento uterino estaria na raiz de problemas na hemodinâmica materno-fetal. A busca por terapêuticas não medicamentosas vem crescendo dentro da área da saúde nos últimos anos. O tratamento manipulativo osteopático é uma terapêutica integrativa complementar de saúde reconhecida pela organização mundial de saúde e aceita pelo sistema único de saúde brasileiro. Método: Trata-se de uma coorte prospectiva realizada com 80 pacientes do ambulatório de pré-natal e da enfermaria de gestantes do Instituto Fernandes Figueira/Fiocruz entre julho de 2021 e setembro de 2022. Foram realizados dois estudos, um estudo transversal com 51 grávidas para avaliar os efeitos hemodinâmicos materno-fetais após o tratamento manipulativo osteopático através da dopplervelocimetria nas gestantes e um estudo prospectivo com 64 gestantes para avaliar a influência do tratamento manipulativo osteopático sobre a intensidade das dores lombar e pélvica, assim como mudanças na sua qualidade de vida. População: foram investigadas gestantes no terceiro trimestre de gestação, acima de 18 anos, e excluídas as gestantes com ruptura prematura de membrana, com malformações fetais, com fetos múltiplos e trabalho de parto ativo. Resultados: Os resultados do estudo transversal após o tratamento manipulativo não foram significantes estatisticamente. No estudo prospectivo, as gestantes foram divididas em dois grupos ≤ 3 e ≥ 4. Observou-se uma melhora significante estatisticamente na intensidade das dores lombar e pélvica em ambos os grupos. Houve melhora nos dois grupos nos índices de qualidade de vida, sendo que no grupo≥ 4 atendimentos todos os resultados foram estatisticamente significativos. Conclusão: a análise dos dados do estudo considerou que o tratamento manipulativo osteopático é seguro para o feto e para gestantes portadoras de comorbidades, não afetando os sinais vitais maternos e nem a circulação uteroplacentária e feto-placentária. Os dados também apontaram que o tratamento osteopático foi eficaz na redução da intensidade da dor lombar e pélvica e efetivo na melhora da qualidade de vida das gestantes.
During pregnancy, several changes women undergo can affect their health status. Studies related to the inability of the body of some pregnant women to accommodate uterine growth would be at the root of problems in maternal-fetal hemodynamics. The search for non-drug treatments has grown in the health area recently. Manipulative osteopathic treatment is a complementary, integrative health therapy recognized by the world health organization and accepted by the Brazilian single health system. Method: This prospective cohort study was carried out with 80 patients from the prenatal clinic and the pregnant women's ward of Instituto Fernandes Figueira/Fiocruz between July 2021 and September 2022. Two studies were carried out, a cross-sectional study with 51 pregnant women to evaluate the maternal-fetal hemodynamic effects after osteopathic manipulative treatment through Doppler velocimetry in pregnant women and a prospective study with 64 pregnant women to evaluate the influence of osteopathic manipulative treatment on the intensity of lumbar and pelvic pain, as well as changes in their quality of life. Population: pregnant women in the third trimester of pregnancy, over 18 years old, were investigated, and pregnant women with premature membrane rupture, fetal malformations, multiple fetuses, and active labor were excluded. Results: The results of the cross-sectional study after manipulative treatment were not statistically significant. Pregnant women were divided into two groups ≤ 3 and ≥ 4 in the prospective study. There was a statistically significant improvement in lumbar and pelvic pain intensity in both groups. There was an improvement in both groups in the quality-of-life indices, and in the group≥ four consultations, all results were statistically achieved. Conclusion: an analysis of the study data found that osteopathic manipulative treatment is safe for the fetus and pregnant women with comorbidities, not affecting maternal signs or uteroplacental and fetal-placental circulation. The data also showed that osteopathic treatment effectively reduced the intensity of lumbar and pelvic pain and improved the quality of life of pregnant women.
Subject(s)
Humans , Female , Pregnancy , Pregnancy Complications, Cardiovascular , Pregnancy Trimester, Third , Quality of Life , Pain Measurement , Pregnancy , Ultrasonography, Doppler , Manipulation, Osteopathic/methods , Hemodynamics , Cohort StudiesABSTRACT
Objetivo: Determinar los hallazgos de retinopatía diabética por ecografía doppler arterial oftálmico en pacientes con diabetes mellitus tipo 2. Métodos: Se efectuó un estudio observacional descriptivo y transversal en 200 órbitas de 100 pacientes diabéticos, a los que se les realizó fondo de ojo para diagnóstico y gradación de la retinopatía diabética. Por interrogatorio y examen físico se determinó el tiempo de diagnóstico de la diabetes y la presencia o ausencia de obesidad. Además, se les hizo ultrasonido orbitario y Doppler carotídeo, y solo en caso de resultar normales, se procedió a evaluar mediante ecografía doppler a las arterias oftálmicas. Resultados: Predominaron los diabéticos entre 40 y 60 años, el sexo masculino, los casos sin retinopatía diabética, y el grupo de más de 10 años de diagnóstico de la diabetes. Se demostró una disminución de la velocidad del flujo y un incremento de la resistencia vascular a nivel de las arterias oftálmicas, en tanto se evidenció asociación significativa de estos parámetros hemodinámicos con el envejecimiento, la presencia o ausencia de obesidad, el tiempo de diagnóstico de la diabetes y la severidad de la retinopatía diabética. Sin embargo, no se encontró asociación significativa con el sexo. Conclusiones: La valoración mediante ecografía doppler de las arterias oftálmicas, haría más completo el estudio y seguimiento de los pacientes con diabetes mellitus tipo 2(AU)
Purpose: To determine the findings of diabetic retinopathy by ophthalmic arterial Doppler ultrasound in patients with type 2 diabetes mellitus. Methods: A descriptive and cross-sectional observational study was carried out in 200 orbits of 100 diabetic patients, who underwent fundus examination for diagnosis and grading of diabetic retinopathy. The time of diagnosis of diabetes and the presence or absence of obesity were determined by interrogation and physical examination. In addition, orbital ultrasound and carotid Doppler were performed, and only if they were normal, the ophthalmic arteries were evaluated by Doppler ultrasound. Results: Diabetic patients between 40 and 60 years of age, from the male gender, cases without diabetic retinopathy, and the group with more than 10 years of diagnosed diabetes predominated. A decrease in flow velocity and an increase in vascular resistance at the level of the ophthalmic arteries were demonstrated, while a significant association of these hemodynamic parameters with aging, presence or absence of obesity, time of diagnosis of diabetes and severity of diabetic retinopathy was evidenced. However, no significant association was found as to gender. Conclusions: Doppler ultrasound assessment of the ophthalmic arteries would make the study and follow-up of patients with type 2 diabetes mellitus more complete(AU)
Subject(s)
Humans , Male , Adult , Middle Aged , Ultrasonography, Doppler/methods , Epidemiology, Descriptive , Cross-Sectional Studies , Observational Studies as TopicABSTRACT
Introducción: La diabetes mellitus es la enfermedad crónica considerada como una de las mayores emergencias sanitarias del siglo XXI en el mundo, que puede desencadenar algunas complicaciones y problemas graves para la salud. Objetivo: Caracterizar a pacientes diabéticos con enfermedad arterial crónica en miembros inferiores según variables clínicas, hemodinámicas y ecográficas. Métodos: Se realizó un estudio observacional, descriptivo y transversal de los 178 pacientes diabéticos con diagnóstico clínico de enfermedad arterial crónica en miembros inferiores, quienes fueron atendidos en el Servicio de Imagenología del Hospital General Docente Dr. Juan Bruno Zayas Alfonso de Santiago de Cuba desde enero de 2017 hasta diciembre de 2019, a los cuales se les realizó examen hemodinámico mediante el índice tobillo-brazo y ecografía Doppler arterial. Resultados: En la investigación primaron los adultos mayores (41,6 %) del sexo femenino (54,0 %), la claudicación intermitente como principal síntoma (57,3 %), el sector femoropoplíteo (34,8 %) según la topografía exacta de las lesiones, así como la estenosis significativa (53,9 %) y la enfermedad arterial periférica moderada (58,3 %). Conclusiones: La mayoría de los pacientes presentó una estenosis significativa detectada por ecografía Doppler, en correspondencia con el diagnóstico de enfermedad arterial periférica moderada por el índice tobillo-brazo. La ecografía Doppler también aportó la topografía exacta de las lesiones.
Introduction: The diabetes mellitus is the chronic disease considered as one of the highest sanitary emergencies in the XXI century in the world that can trigger some complications and serious health problems. Objective: To characterize diabetic patients with arterial chronic disease in lower limbs according to clinical, hemodynamic and ultrasound variables. Methods: An observational, descriptive and cross-sectional study of the 178 diabetic patients with clinical diagnosis of arterial chronic disease in lower limbs was carried out, who were assisted in the Imaging Service of Dr. Juan Bruno Zayas Alfonso General Hospital in Santiago de Cuba from January, 2017 to December, 2019, to whom hemodynamic exam by means of the ankle-brachial index and arterial Doppler ultrasound was carried out. Results: In the investigation there was a prevalence of the elderly (41.6 %) from the female sex (54.0 %), the intermittent abandonment as main symptom (57.3 %), the femoropopliteal sector (34.8 %) according to the exact topography of the lesions, as well as the significant stenosis (53.9 %) and the moderate peripheral arterial disease (58.3 %). Conclusions: Most of the patients presented a significant stenosis according to Doppler ultrasound, in correspondence with the diagnosis of moderated peripheral arterial disease by the ankle-brachial index. The Doppler ultrasound also contributed the exact topography of the lesions.
Subject(s)
Diabetes Mellitus , Peripheral Arterial Disease , Ultrasonography, Doppler , Lower ExtremityABSTRACT
The evaluation of labor is the clinical process by which variables are analyzed in order to determine whether the patient is in labor, which by definition includes regular uterine contractions that increase in frequency and intensity, associated with dilation cervical. This is done through the anamnesis and physical examination, specifically through the evaluation of contractions and vaginal examination, the latter is intended to specify the degree of dilation, cervical effacement that the patient presents and also allows to a certain degree, establish the presentation, attitude and variety of position in which the fetus is located. From this premise, it is proposed that vaginal examination, since it is operator dependent, is not an objective evaluation, therefore, there is a need to reach consensus on the evaluation, and in order to carry it out, evaluation with ultrasound is proposed, which has as a purpose to objectify the variety of position and presentation of the fetus. Due to the above, this article aims to capture the knowledge that is currently possessed about the uses and methodology that intrapartum ultrasound presents.
Subject(s)
Humans , Female , Pregnancy , Umbilical Arteries/diagnostic imaging , Cesarean Section , Placenta/diagnostic imaging , Pregnancy Outcome , Ultrasonography, Prenatal , Ultrasonography, Doppler , Middle Cerebral Artery/diagnostic imagingABSTRACT
Objetivo: Determinar los hallazgos por ecografía Doppler arterial oftálmica en pacientes con hipertensión arterial primaria. Métodos: Se efectuó un estudio observacional descriptivo y transversal con 202 órbitas de 101 pacientes hipertensos, a los que se les realizó fondo de ojo para diagnóstico y gradación de la retinopatía hipertensiva. Por interrogatorio y examen físico se identificaron como factores de riesgo aterosclerótico el consumo excesivo de alcohol y la obesidad. Además, se les hizo ultrasonido orbitario y Doppler carotídeo, y solo en caso de resultar normales, se procedió a evaluar mediante ecografía Doppler las arterias oftálmicas. Resultados: Predominaron los hipertensos entre 40 y 60 años de edad, el sexo masculino, el color mestizo de piel, los casos sin retinopatía hipertensiva, y el grupo entre 10 y 20 años de diagnosticada la hipertensión. Se demostró un incremento de la velocidad del flujo y de la resistencia vascular a nivel de las arterias oftálmicas. En tanto, se evidenció asociación significativa de estos parámetros hemodinámicos con el envejecimiento y el tiempo de diagnóstico de la hipertensión. Sin embargo, no se comprobó asociación significativa con el sexo, el color de la piel, y la presencia o ausencia de obesidad, consumo excesivo de alcohol, y retinopatía hipertensiva independientemente de su gravedad. Conclusiones: La evaluación de las arterias oftálmicas mediante ecografía Doppler permite hacer un estudio y seguimiento más integral de los pacientes con hipertensión arterial primaria(AU)
Objective: To determine ophthalmic arterial Doppler ultrasound findings in patients with primary arterial hypertension. Methods: A descriptive and cross-sectional observational study was carried out with 202 orbits of 101 hypertensive patients, who underwent fundus examination for diagnosis and grading of hypertensive retinopathy. By interrogation and physical examination, excessive alcohol consumption and obesity were identified as atherosclerotic risk factors. In addition, orbital ultrasound and carotid Doppler were performed, and only if they were normal, the ophthalmic arteries were evaluated using Doppler ultrasound. Results: Hypertensive patients between 40 and 60 years of age, male, mixed skin color, cases without hypertensive retinopathy, and the group between 10 and 20 years after hypertension diagnosis predominated. An increase in flow velocity and vascular resistance at the level of the ophthalmic arteries was demonstrated. Meanwhile, a significant association of these hemodynamic parameters with aging and time of diagnosis of hypertension was evidenced. However, no significant association was found with gender, skin color, and the presence or absence of obesity, excessive alcohol consumption, and hypertensive retinopathy regardless of its severity. Conclusions: Evaluation of the ophthalmic arteries using Doppler ultrasound allows a more comprehensive study and follow-up of patients with primary arterial hypertension(AU)