Lesiones metastásicas a glándula tiroides. Una serie de casos / Metastatic lesions to the thyroid gland. Case series

Las lesiones metastásicas representan hasta un 3 % de los tumores malignos de la glándula tiroides. La mayoría de los casos se originan de tumores de células renales y de pulmón. El abordaje diagnóstico implica una alta sospecha clínica en pacientes con primarios conocidos, sin embargo, puede ser la manifestación inicial de una enfermedad maligna extensa no diagnosticada hasta en un 20 % a 40 % de los pacientes. La biopsia por aguja fina ha demostrado buen rendimiento para el diagnóstico de los nódulos metastásicos. El pronóstico y la opción del tratamiento quirúrgico dependen del control local del primario y del estado de la enfermedad sistémica asociada, por lo tanto, debe ser individualizado. Por lo general, hasta un 80 % de los pacientes con compromiso de la tiroides tienen enfermedad metastásica multiorgánica, y la intención del tratamiento quirúrgico es con fines paliativos para prevenir las complicaciones derivadas de la extensión local de la enfermedad a las estructuras del tracto aerodigestivo superior en el cuello. Se presenta a continuación, una serie de seis casos de pacientes con lesiones metastásicas a glándula tiroides con primarios en riñón, mama y de melanomas

Metastatic lesions represent up to 3% of malignant tumors of the thyroid gland. Most cases originate from lung and renal cell tumors. The diagnostic approach implies a high clinical suspicion in patients with known primaries, however, it can be the initial manifestation of an extensive undiagnosed malignant disease in up to 20% to 40% of patients. Fine-needle biopsy has shown good performance for the diagnosis of metastatic nodules. The prognosis and the option of surgical treatment depend on the local control of the primary condition and the state of the associated systemic disease, therefore it must be individualized. In general, up to 80% of patients with thyroid involvement have multi-organ metastatic disease and surgical treatment is intended to be palliative to prevent complications resulting from local extension of the disease to structures of the upper aerodigestive tract in the neck. A case series of six patients with metastatic lesions to the thyroid gland with primaries in the kidney, breast and melanomas is presented below

Tuberculosis cutánea esporotricoide en la Amazonía peruana: reporte de caso / Sporotrichoid cutaneous tuberculosis in the peruvian amazon: case report

RESUMEN La tuberculosis cutánea es una presentación rara de la infección por Mycobacterium tuberculosis. Se presenta el caso de una mujer sin antecedentes médicos de importancia, con un tiempo de enfermedad de año y medio, caracterizado por lesiones tipo esporotricoide, con diseminación linfocutánea en miembro superior derecho, de evolución lentamente progresiva. Se realizó un estudio histopatológico encontrándose células gigantes tipo Langhans y escasa necrosis. El paciente recibió terapia de esquema sensible antituberculoso, con evolución favorable.

ABSTRACT Cutaneous tuberculosis is a rare presentation of Mycobacterium tuberculosis infection. We present the case of a woman without important medical history, with a disease period of one year and a half, characterized by sporotrichoid-like lesions, with lymphocutaneous dissemination in the right upper limb, and with slowly progressive evolution. The histopathological tests revealed Langhans type giant cells and scarce necrosis. The patient received therapy with a sensitive antituberculous scheme, and evolved favorably.

Síndrome de la mano inútil con astereognosia secundaria a un astrocitoma cervical / Useless hand syndrome with astereognosis secondary to a cervical astrocytoma

Resumen El presente caso es un ejemplo del síndrome de la mano inútil de Oppenheim secundario a un astrocitoma cervical alto. La pérdida sensorial propioceptiva y discriminativa suspendida con conservación de la termoalgesia y el tacto crudo en ambas extremidades superiores es secundaria al daño a la entrada de la raíz dorsal y al núcleo cuneiforme. La torpeza y las dificultades para una prensión precisa con la mano se deben al daño del núcleo proprioespinal en las astas dorsales a nivel C3-C4. Este núcleo integra influencias excitadoras descendentes del tracto corticoespinal e interneuronas inhibitorias controladas por los sistemas descendentes y las aferencias de las extremidades anteriores. Probablemente la pérdida de las aferentes cervicales propioceptivas inhibitorias sea la culpable de las dificultades para agarrar con las manos.

The present case is an example of the useless hand syndrome of Oppenheim secondary to a high cervical astrocytoma. The suspended proprioceptive and discriminative sensory loss with conservation of thermoalgesia and crude touch in both upper extremities is secondary to damage to dorsal root entry and cuneate nucleus. The clumsiness and difficulties in precise grasping with the hand are due to damage of the propriospinal nucleus in the dorsal horns at C3-C4 level. This nucleus integrates descending excitatory influences from corticospinal tract and inhibitory interneurons controlled by descending systems and the forelimb afferents. Probably the loss of the inhibitory proprioceptive cervical afferents is the culprit of the difficulties in grasping by the hands.

Effect of concurrent training (aerobic+resistance) more static stretching on flexibility in women with breast cancer / Efeito do treinamento concorrente (aeróbio + resistência) mais alongamento estático na flexibilidade em mulheres com câncer de mama

Objective. was to assess flexibility in women with breast cancer who underwent concurrent training (aerobic+resistance) (CT) more static stretching. Methods. This was a controlled pilot study, with 31 women (age 30 to 59) under breast cancer treatment, 14 women were allocated to a training group (TG) who underwent CT more static stretching, concomitant to hospital treatment and 17 women for the control group (CG) who only underwent hospital treatment. The CT more static stretching was performed in 12 weeks with 5 sessions per week, three sessions (aerobic+resistance) and two sessions (stretching exercises) on alternate days. The flexibility of the shoulder was measured by means of the 360º Sanny pendulum goniometer and the flexibility of the lower limbs was assessed through the sit-and-reach test. Data were analyzed using repeated measures ANOVA Test and Bonferroni Post-hoc using SPSS 21 software, with α of 5%. Results. The TG presented increased flexibility in the horizontal abduction of the right shoulder (p=0.001) and in the lower limbs (p<0.001), but the CG showed a reduction in the horizontal abduction of the right shoulder (p=0.003). The effect size for horizontal abduction of the right shoulder was medium (p=0.508) and for the lower limbs was large (p=0.839). Conclusion. CT more static stretching may be a therapeutic intervention to increase flexibility of upper and lower limbs in women with breast cancer. (AU)

Objetivo. Avaliar a flexibilidade em mulheres com câncer de mama que realizaram treinamento concorrente (aeróbio + resistência) (TC) mais alongamento estático. Métodos. Este foi um estudo piloto controlado, com 31 mulheres (de 30 a 59 anos) em tratamento para câncer de mama, 14 mulheres foram alocadas em um grupo de treinamento (GT) que realizaram TC mais alongamento estático, concomitante a tratamento hospitalar e 17 mulheres para o grupo de controle (GC) que somente realizaram tratamento hospitalar. O TC mais alongamento estático foram realizados em 12 semanas com 5 sessões semanais, três sessões (aeróbia + resistência) e duas sessões (exercícios de alongamento) em dias alternados. A flexibilidade do ombro foi medida por meio do goniômetro de pêndulo 360º Sanny e a flexibilidade de membros inferiores foi avaliada por meio do teste de sentar e alcançar. Os dados foram analisados usando o Teste ANOVA de medidas repetidas e Post-hoc de Bonferroni no software SPSS 21, com α de 5%. Resultados. O GT apresentou aumento da flexibilidade na abdução horizontal do ombro direito (p=0,001) e nos membros inferiores (p<0,001), mas o GC apresentou redução da abdução horizontal do ombro direito (p=0,003). O tamanho do efeito para abdução horizontal do ombro direito foi médio (p=0,508) e para membros inferiores foi grande (p=0,839). Conclusão. O TC mais alongamento estático podem ser uma intervenção terapêutica para aumentar a flexibilidade de membros superiores e inferiores em mulheres com câncer de mama. (AU)

Are craniocervical flexion test and the pectoralis minor index useful tests for patients with subacromial pain syndrome? / Are craniocervical flexion test and the pectoralis minor index useful tests for patients with subacromial pain syndrome?

Cervical disorders and the shortening of the pectoralis minor are advocated to play an important role in patients with subacromial pain syndrome, despite the absence of evidence. This study aimed to compare the deep cervical flexor muscle function and the shortening of the pectoralis minor between patients with subacromial pain syndrome and controls. Secondarily, this study aimed to analyze the relationship of clinical tests with pain and disability among patients. This is a case-control study with 32 patients with subacromial pain syndrome [mean age: 33 ± 6.9 years; sex: 22 (65.6%) men; right dominance: 31 (96.9%)] and 32 controls matched for age, sex, handedness, and affected side. Participants filled the Numerical Pain Rating Scale, the Shoulder Pain and Disability Index; and performed the clinical tests which were compared between patients and controls. Pectoralis minor length of the patient's group (median = 9.0) was similar to the controls (median = 9.7) (U = 421.5; p = 0.22). The deep neck muscle function presented no statistical difference between patients and controls (χ2 = 4.319; p = 0.504). There was no statistically significant correlation between clinical tests and patient self-reported measures. Therefore, deep cervical flexor muscle and the pectoralis minor muscle were not impaired in patients with subacromial pain syndrome and did not show a relationship with self-reported measures.

Distúrbios cervicais e o encurtamento do músculo peitoral menor são apontados como tendo um papel importante em pacientes com síndrome da dor subacromial, apesar da ausência de evidências. Este estudo teve como objetivo comparar a função dos músculos flexores cervicais profundos e o encurtamento do músculo peitoral menor entre pacientes com síndrome da dor subacromial e controles. Secundariamente, este estudo objetivou analisar a relação dos testes clínicos com a dor e incapacidade entre os pacientes com síndrome da dor subacromial. Trata-se de um estudo caso-controle com 32 pacientes com síndrome da dor subacromial [idade: 33 ± 6,9 anos; sexo: 22 (65,6%) homens; dominância direita: 31 (96,9%)] e 32 controles pareados por idade, sexo, lateralidade e lado afetado. Os participantes preencheram a Numerical Pain Rating Scale, o Shoulder Pain and Disability Index, realizaram os testes clínicos e os resultados dos pacientes e controles foram comparados. O comprimento do músculo peitoral menor no grupo de pacientes (mediana = 9,0) foi semelhante ao grupo controle (mediana = 9,7) (U = 421,5; p = 0,22). A função do músculo flexor cervical profundo não apresentou diferença estatística entre pacientes e controles (χ2 = 4,319; p = 0,504). Não houve correlação estatisticamente significativa entre os testes clínicos e as medidas relatadas pelos pacientes. Portanto, o músculo flexor cervical profundo e o músculo peitoral menor não foram prejudicados em pacientes com síndrome da dor subacromial e não mostraram relação com medidas autorreferidas.

Efeitos do treinamento resistido nos músculos escapulares nas epicondilalgias: revisão sistemática e metanálise / Effects of resistant training on scapular muscles in epicondylalgia: systematic review and meta-analysis

As epicondilalgias medial e lateral são as causas mais frequentes de sintomas dolorosos nos membros superiores. Observa-se um aumento no número de publicações sobre os efeitos do treino da musculatura escapular no manejo clínico das epicondilalgias, porém desconhecemos uma revisão sistemática que avalie os efeitos do treinamento resistido nos músculos escapulares nessa condição. Objetivo: revisar sistematicamente os efeitos do treinamento resistido nos músculos escapulares nas epicondilalgias. Metodologia: foi realizada uma busca científica (SciELO, PubMed, LILASCS, PEDro) de estudos clínicos controlados sobre os efeitos do treinamento resistido nos músculos escapulares nas epicondilalgias publicados até maio 2021. A escala de PEDro foi aplicada para avaliação da qualidade metodológica. Resultados: foram encontrados 266 artigos e 3 foram incluídos na revisão sistemática. Os estudos inclusos enfatizaram o treinamento dos músculos trapézio médio, trapézio inferior e serrátil anterior associados a reabilitação convencional. Através da análise individual dos estudos observa-se efeitos positivos do treino escapular na dor, na função (Patient Rated Tennis Elbow Evaluation Questionnaire ­ PRTEE) e na força de preensão manual em indivíduos com epicondilalgias lateral. A metanálise revela que adicionar exercícios escapulares a fisioterapia convencional reduz a dor (EVA 0-10) em 1.23 (95% IC, 2,00-0,47, p=0,002, I2=47%, p para heterogeidade = 0.17) e aumenta a função (PRTEE 0-100) em 5.47 (95% IC, 10,00-0,93, p=0,02, I2=0%, p para heterogeidade = 0.84) na epicondilalgias lateral. A média de pontuação da escala PEDro foi de 6,33/10. Conclusão: o treinamento resistido dos músculos escapulares associados a reabilitação reduzem dor e aumentam função em indivíduos com epicondilalgia lateral. Sugere-se a realização de mais estudos com melhor qualidade metodológica para avaliar a importância do fortalecimento dos músculos escapulares em indivíduos com epicondilalgias. (AU)

Medial and lateral epicondylalgia are the most requente causes of painful symptoms in the upper limbs. There is na increase in the number of publications on the effects of scapular muscle training in the clinical management of epicondylalgia, but we do not know of a systematic review that assesses the effects of resistance training on scapular muscles in this condition. The aim of the study was to systematically review the effects of resistance training on scapular muscles in epicondylalgia. A scientific search (SciELO, PubMed, LILASCS, PEDro) of controlled clinical studies on the effects of resistance training for the scapular muscles in epicondylagias published until May 2021 was performed. The PEDro scale was applied to assess the methodological quality. 266 articles were found and 3 were included in the systematic review. The included studies emphasized the training of the middle trapezius, lower trapezius and serratus anterior muscles associated with conventional rehabilitation. Through the individual analysis of the studies, positive effects of scapula training on pain, function Patient Rated Tennis Elbow Evaluation Questionnaire ­ PRTEE) and handgrip strength were observed in individuals with lateral epicondylalgia. The meta-analysis reveals that adding scapular exercises to conventional physical therapy reduces pain (VAS 0-10) by 1.23 (95% CI, 2.00-0.47, p=0.002, I2=47%, p for heterogeneity = 0.17) and increases function (PRETEE 0-100) by 5.47 (95% CI, 10.00- 0.93, p=0.02 I2=0%, p for heterogeneity = 0.84) in lateral epicondylalgia. The average score of the studies on the PEDro scal e was 6.33 out 10. In conclusion, resistance training of scapular muscles associated with rehabilitation reduces pain the increases function in individuals with lateral apicondylalgia. It is suggested that more studies be carried out with better methodological quality to assess the importance of strengthening the scapular muscles in individuals with epicondylalgia. (AU)

Tratamento endovascular de doença oclusiva venosa central com fístula arteriovenosa funcionante / Endovascular treatment of central vein occlusion in patients with functioning arteriovenous fistulas

Resumo Contexto A maior sobrevida dos doentes dialíticos somada à incapacidade de obtenção de órgãos suficientes para atender a demanda, bem como à dificuldade de acesso aos serviços de saúde, levou ao aumento da fila para transplante e ao prolongamento do tempo de utilização do acesso venoso central para hemodiálise. A etiologia mais comum de estenose de veia central é o acesso venoso central prolongado, pelas lesões intimais decorrentes da presença do cateter. Objetivos Avaliar resultados de angioplastia para tratamento de doença oclusiva venosa central com fístula arteriovenosa periférica funcionante. Métodos Estudo tipo coorte retrospectivo com revisão de prontuários de 47 doentes com lesões estenóticas ou oclusivas. A avaliação dos doentes foi realizada em 30 dias, 6 meses e 1 ano após a recanalização ou correção da estenose com ATP ou ATP/aplicação de stent. Resultados Lesões estenóticas foram encontradas em 25 doentes (53%), e oclusões, em 22 (47%) doentes. A angioplastia percutânea transluminal (ATP) com stent foi utilizada em 64% dos doentes, e angioplastia isolada com balão, em 36% deles. A análise de resultados clínicos mostrou elevada taxa de melhora clínica precoce (30 dias) em 82% dos doentes (intervalo de confiança [IC] 71-93%). Após 1 ano de seguimento, a taxa de perviedade primária foi de 57%, e a taxa de perviedade primária assistida foi de 72% (IC 57-84%). Conclusão O tratamento endovascular das estenoses ou oclusões de veia central sugere melhora clínica dos sintomas e taxas adequadas de perviedade no período de 1 ano, apesar da limitação no tamanho amostral.

Abstract Background The increased survival of dialysis patients and the inability to obtain sufficient organs to meet demand for transplantation, compounded by poor access to health services, have caused the transplant waiting lists to grow, extending the time spent using central venous accesses for hemodialysis. The most common etiology of central vein stenosis is prolonged central venous access, due to intimal injuries caused by the presence of the catheter. Objectives To assess the results of angioplasty to treat central vein occlusion in patients with functioning peripheral arteriovenous fistulas. Methods Retrospective cohort study with review of medical records from 47 patients with stenotic or occlusive lesions. Patients were assessed at 30 days, 6 months, and 1 year after recanalization or correction of stenosis with transluminal percutaneous angioplasty (TPA) or TPA/stenting. Results Stenotic lesions were detected in 25 patients (53%) and occlusions were found in 22 (47%) patients. TPA with stenting was used in 64% of patients and balloon angioplasty in isolation was used in 36%. Analysis of clinical results showed a high rate of early clinical improvement (30 days), seen in 82% of patients (confidence interval [CI] 71-93%). After 1 year of follow-up, the primary patency rate was 57% and the assisted primary patency rate was 72% (CI 57-84%). Conclusions Endovascular treatment of central vein stenosis or occlusions suggests clinical improvement of symptoms and adequate rates of patency at 1 year, notwithstanding the limited sample size.

Prevention from PICC-related venous thrombosis in the upper limbs of malignant tumor patients with moxibustion combined with plucking at Jiquan (HT 1): a randomized controlled trial / 中国针灸

OBJECTIVE@#To observe the clinical effect of moxibustion combined with plucking technique at Jiquan (HT 1) for preventing peripherally inserted central catheter (PICC)-related venous thrombosis in the upper limbs of malignant tumor patients.@*METHODS@#A total of 80 malignant tumor patients undergoing PICC were randomized into an observation group and a control group, 40 cases in each one. In the control group, the routine care for PICC was exerted. In the observation group, besides the routine care, moxibustion combined with plucking technique at Jiquan (HT 1) was added. Mild moxibustion was exerted along the venous distribution of PICC (avoiding the entry site) for 10 to 15 min, and then, the circling moxibustion was applied to Quchi (LI 11), Xuehai (SP 10) and Tianfu (LU 3), 3 to 5 min at each acupoint. Finally, plucking technique was given at Jiquan (HT 1) for 5 to 10 min. This combined therapy was intervened since the 2nd day of PICC placement, once daily, 5 times a week, for 3 weeks totally. The incidence of the PICC-related venous thrombosis in the upper limbs was compared between the two groups on day 42 of placement. On day 2, 7, 14, 21, 28, 35 and 42 of PICC placement, the peak systolic velocity (PSV) and the end-diastolic velocity (EDV) of the subclavicular vein on the placement side were observed separately in the two groups.@*RESULTS@#The incidence of the PICC-related venous thrombosis in the upper limbs in the observation group was lower than that in the control group (2.5% [1/40] vs 17.5% [7/40], P<0.05). From day 7 to 35 of PICC placement, PSV of the subclavicular vein on the placement side was higher than that on the day 2 of PICC placement in the observation group (P<0.05). On day 28 and 42 of PICC placement, PSV of the subclavicular vein on the placement side was lower than that on the day 2 of PICC placement in the control group (P<0.05). In the observation group, EDV of the subclavicular vein on the placement side was higher than that on the day 2 of PICC placement from day 7 to 28 of PICC placement (P<0.05). In the control group, EDV of the subclavicular vein on the placement side from day 28 to 42 of PICC placement was lower than that on the day 2 of PICC placement (P<0.05). From day 7 to 42 of PICC placement, PSV and EDV of the subclavicular vein on the placement side in the observation group were all higher than those in the control group (P<0.01, P<0.05).@*CONCLUSION@#The combined treatment of moxibustion with plucking technique at Jiquan (HT 1) can effectively prevent PICC-related venous thrombosis in the upper limbs and improve venous blood flow velocity in malignant tumor patients.

Clinical observation on wrist-ankle acupuncture for shoulder-hand syndrome phaseⅠafter stroke / 中国针灸

OBJECTIVE@#To compare the clinical efficacy between wrist-ankle acupuncture and conventional acupuncture on shoulder-hand syndrome (SHS) phaseⅠafter stroke.@*METHODS@#A total of 64 patients with SHS phaseⅠafter stroke were randomized into a wrist-ankle acupuncture group and a conventional acupuncture group, 32 cases in each group. On the basis treatment of internal medicine and conventional rehabilitation, wrist-ankle acupuncture was applied at upper 4 area, upper 5 area and upper 6 area on the affected side in the wrist-ankle acupuncture group, while acupuncture was applied at Jianyu (LI 15), Quchi (LI 11), Shousanli (LI 10), etc. on the affected side in the conventional acupuncture group. The treatment was given 30 min each time, once a day, 5 days a week for 3 weeks in both groups. Before and after treatment, the visual analogue scale (VAS) score, degree of hand swelling, shoulder-hand syndrome scale (SHSS) score, Fugl-Meyer assessment for upper extremity (FMA-UE) score and modified Barthel index (MBI) score were observed, and the clinical therapeutic effect was evaluated in both groups.@*RESULTS@#After treatment, the VAS scores, degree of hand swelling and SHSS scores were decreased (P<0.05), and the FMA-UE scores and MBI scores were increased (P<0.05) compared before treatment in both groups; in the wrist-ankle acupuncture group, the VAS score, degree of hand swelling and SHSS score were lower (P<0.05), and the FMA-UE score and MBI score were higher (P<0.05) than those in the conventional acupuncture group. The total effective rate was 96.9% (31/32) in the wrist-ankle acupuncture group, which was superior to 90.6% (29/32) in the conventional acupuncture group (P<0.05).@*CONCLUSION@#Wrist-ankle acupuncture can effectively relieve pain and hand swelling, improve motor function of upper extremity and self-care ability of daily life in patients with shoulder-hand syndrome phaseⅠafter stroke, the therapeutic effect is superior to conventional acupuncture.

Effect of electroacupuncture at antagonistic muscle and agonistic muscle on motor function in patients with upper-extremity spasticity after stroke / 中国针灸

OBJECTIVE@#To compare the improvement effect between simultaneous electroacupuncture at antagonistic muscle and agonistic muscle and simple electroacupuncture at antagonistic muscle on spasticity degree, upper-extremity motor function and activity of daily living in patients with upper-extremity spasticity after stroke.@*METHODS@#A total of 60 patients with upper-extremity spasticity after stroke were randomized into a comprehensive group (30 cases, 1 case dropped off) and an antagonistic muscle group (30 cases, 2 cases dropped off). In the antagonistic muscle group, acupuncture was applied at Jianyu (LI 15), Binao (LI 14), Zhouliao (LI 12), Shousanli (LI 10), Waiguan (TE 5) and Houxi (SI 3), electric stimulation was attached to Jianyu (LI 15)-Binao (LI 14), Zhouliao (LI 12)-Shousanli (LI 10) and Waiguan (TE 5)-Houxi (SI 3), with discontinuous wave, 15 Hz in frequency. On the basis of the treatment in the antagonistic muscle group, acupuncture was applied at Tianquan (PC 2), Chize (LU 5), Jianshi (PC 5) and Daling (PC 7) in the comprehensive group, electric stimulation was attached to Tianquan (PC 2)-Chize (LU 5) and Jianshi (PC 5)-Daling (PC 7), with continuous wave, 5 Hz in frequency. The treatment was given once a day, 6 days a week for 4 weeks in the two groups. Before and after treatment, the scores of modified Ashworth scale (MAS), Fugl-Meyer assessment upper extremity scale (FMA-UE) and modified Barthel index (MBI) scale were observed in the two groups.@*RESULTS@#Compared before treatment, the MAS scores of elbow flexors and wrist flexors after treatment were decreased (P<0.05), the scores of FMA-UE and MBI scale after treatment were increased in the two groups (P<0.05). The scores of FMA-UE and MBI scale after treatment in the comprehensive group were higher than those in the antagonistic muscle group (P<0.05).@*CONCLUSION@#Simultaneous electroacupuncture at antagonistic muscle and agonistic muscle and simple electroacupuncture at antagonistic muscle can both improve the spasticity degree in patients with upper-extremity spasticity after stroke, however, the former can better restore motor function and improve activity of daily living.

Research progress on intelligent assessment system for upper limb function of stroke patients / 生物医学工程学杂志

At present, the upper limb function of stroke patients is often assessed clinically using a scale method, but this method has problems such as time-consuming, poor consistency of assessment results, and high participation of rehabilitation physicians. To overcome the shortcomings of the scale method, intelligent upper limb function assessment systems combining sensors and machine learning algorithms have become one of the hot research topics in recent years. Firstly, the commonly used clinical upper limb functional assessment methods are analyzed and summarized. Then the researches on intelligent assessment systems in recent years are reviewed, focusing on the technologies used in the data acquisition and data processing parts of intelligent assessment systems and their advantages and disadvantages. Lastly, the current challenges and future development directions of intelligent assessment systems are discussed. This review is hoped to provide valuable reference information for researchers in related fields.

Mechanical Design and Research of Wearable Exoskeleton Assisted Robot for Upper Limb Rehabilitation / 中国医疗器械杂志

Based on the biomechanical mechanism of human upper limb, the disadvantages of traditional rehabilitation training and the current status of upper limb rehabilitation robot, a six degree of freedom, flexible adjustment, wearable upper limb rehabilitation exoskeleton design scheme is proposed. Firstly, the mechanics of each joint of the upper limb is analyzed, and the virtual prototype design of the whole mechanical structure of the upper limb rehabilitation wearable exoskeleton is carried out by using CATIA three-dimensional software. The tooth transmission of the forearm and the upper arm single row four point contact ball bearing with internal/external rotation and the shoulder flexible passive adjustment mechanism (viscoelastic damper) are innovatively designed. Then, the joints of the upper limb rehabilitation exoskeleton are analyzed, theoretical analysis and calculation of the driving torque, the selection of the motor and gearbox of each driving joint are carried out. Finally, the whole finite element analysis of the upper limb exoskeleton is carried out. The research and experimental results showed that the design scheme of the upper limb exoskeleton assist structure is highly feasible, which can help the patients with upper limb paralysis and motor dysfunction self-rehabilitation.

Fatigue analysis of upper limb rehabilitation based on surface electromyography signal and motion capture / 生物医学工程学杂志

At present, fatigue state monitoring of upper limb movement generally relies solely on surface electromyographic signal (sEMG) to identify and classify fatigue, resulting in unstable results and certain limitations. This paper introduces the sEMG signal recognition and motion capture technology into the fatigue state monitoring process and proposes a fatigue analysis method combining an improved EMG fatigue threshold algorithm and biomechanical analysis. In this study, the right upper limb load elbow flexion test was used to simultaneously collect the biceps brachii sEMG signal and upper limb motion capture data, and at the same time the Borg Fatigue Subjective and Self-awareness Scale were used to record the fatigue feelings of the subjects. Then, the fatigue analysis method combining the EMG fatigue threshold algorithm and the biomechanical analysis was combined with four single types: mean power frequency (MPF), spectral moments ratio (SMR), fuzzy approximate entropy (fApEn) and Lempel-Ziv complexity (LZC). The test results of the evaluation index fatigue evaluation method were compared. The test results show that the method in this paper has a recognition rate of 98.6% for the overall fatigue state and 97%, 100%, and 99% for the three states of ease, transition and fatigue, which are more advantageous than other methods. The research results of this paper prove that the method in this paper can effectively prevent secondary injury caused by overtraining during upper limb exercises, and is of great significance for fatigue monitoring.

Endovascular Repair of Primary Thoracic Aortic Mural Thrombus Following Upper Limb Embolization

Abstract We report the case of a 41-year-old female who presented with left upper limb embolization due to primary thoracic aortic mural thrombus; this latter represented an uncommon condition with difficult diagnosis and a high rate of life-threatening complications. Upper extremities embolization is extremely rare because it usually occurs in the lower limbs. Management strategy is still controversial, and no clear guidelines indicate superiority of either conservative or invasive treatment approach to date. Our report illustrates how endovascular exclusion of thoracic aortic mural thrombus has the advantage to be a low-risk procedure that represents a definitive therapy.

Pseudoaneurisma humeral secundario a punción arterial inadvertida / Brachial artery pseudoaneurysm secondary to inadvertent arterial puncture

RESUMEN Los pseudoaneurismas de la arteria humeral son infrecuentes, pero pueden asociarse a complicaciones de alta morbilidad como la isquemia de miembro superior. Comunicamos un caso de pseudoaneurisma humeral en el pliegue del codo, que se presentó como tumor pulsátil con leve disminución de la temperatura y parestesias en la mano homolateral de un año de evolución, debido a una punción arterial inadvertida durante la venopunción para extracción de sangre. Se trató con éxito mediante resección quirúrgica más reconstrucción vascular con bypass húmero-cubital y bypass húmero-radial ambos con vena safena. Se discuten las diversas opciones terapéuticas disponibles para los pseudoaneurismas humerales considerando las características anatómicas y la sintomatología del paciente.

ABSTRACT Brachial artery pseudoaneurysms are rare but can be associated with severe complications as ischemia of the upper extremity. We report a case of a brachial artery pseudoaneurysm in the crease of the elbow presenting as a pulsating mass with progressive growth over the past year. The ipsilateral hand was sightly cold and presented paresthesia. The lesion was due to inadvertent arterial puncture during venipuncture. The pseudoaneurysm was successfully treated with surgical resection and vascular reconstruction with a brachial to ulnar artery bypass and brachial to radial artery bypass with saphenous vein graft. The different therapeutic options available for brachial artery pseudoaneurysms are discussed, considering the anatomic characteristics and patients' symptoms.

Evaluación del tratamiento de linfangiomas con bleomicina en población pediátrica de 0 a 18 años / Evaluation of the treatment of lymphangiomas with bleomycin in a pediatric population aged 0 to 18 years

INTRODUCCIÓN. Los linfangiomas son una malformación infrecuente a escala mundial y constituye una preocupación para los padres del infante; está asociado a problemas estéticos y a posibles efectos deletéreos debido a la obstrucción o compresión de órganos vitales. Se ha descrito a la escleroterapia como la mejor opción de tratamiento. OBJETIVO. Determinar la eficiencia del tratamiento con bleomicina en linfangiomas en la población pediátrica de 0 a 18 años. MATERIALES Y MÉTODOS. Estudio transversal analítico retrospectivo. Población y muestra conocida de 20 datos de Historias Clínicas electrónicas de pacientes diagnosticados con linfangiomas y tratados con bleomicina en el Hospital de Especialidades Carlos Andrade Marín, desde enero 2015 a enero 2018. Criterios de inclusión: pacientes de 0 a 18 años de edad con diagnóstico de linfangioma mediante ecografía y angiotomografía computarizada. Criterios de exclusión: pacientes mayores de 18 años de edad o sospecha diagnóstica de linfangioma sin estudios de imagen, y/o que no acudieron a la cita de control, pacientes diagnosticados de linfangioma que no recibieron bleomicina para su tratamiento, niños con otras malformaciones vasculares. El análisis de datos se realizó en el programa estadístico International Business Machines Statistical Package for the Social Sciences. RESULTADOS. La mediana de edad en mujeres fue de 6,25 años y 3,8 años en hombres. 10 pacientes fueron hombres. El promedio de seguimiento fue de 26,86 +/- 16,78 meses. El tamaño promedio de los linfangiomas fue de 5,77 +/- 3,73 cm. La localización más frecuente fue cervical con un 52,38%. La mayoría fueron macronodulares con un 85,71%. La respuesta fue buena o excelente en el 81,00% de los casos con la primera infiltración y subió al 95,00% con la segunda y tercera, según requerimiento. CONCLUSIÓN. El tratamiento de los linfangiomas con bleomicina fue muy efectivo en la población estudiada.

INTRODUCTION. Lymphatic malformation is a rare malformation worldwide and is a concern for the parents of the infant; it is associated with aesthetic problems and possible deleterious effects due to obstruction or compression of vital organs. Sclerotherapy has been described as the best treatment option. OBJECTIVE. To determine the efficiency of bleomycin treatment in lymphangiomas in the pediatric population aged 0 to 18 years. MATERIALS AND METHODS. Retrospective analytical cross-sectional study. Population and known sample of 20 data from Electronic Medical Records of patients diagnosed with lymphangiomas and treated with bleomycin at the Carlos Andrade Marín Specialties Hospital, from January 2015 to January 2018. Inclusion criteria: patients aged 0 to 18 years with diagnosis of lymphangioma by ultrasound and computed angiotomography. Exclusion criteria: patients older than 18 years of age or diagnostic suspicion of lymphangioma without imaging studies, and/or who did not attend the control appointment, patients diagnosed with lymphangioma who did not receive bleomycin for treatment, children with other vascular malformations. Data analysis was performed in the statistical program International Business Machines Statistical Package for the Social Sciences. RESULTS. The median age in women was 6,25 years and 3,8 years in men. Ten patients were men. The average follow-up was 26,86 +/- 16,78 months. The average size of the lymphatic malformations was 5,77 +/- 3,73 cm. The most frequent location was cervical with 52,38%. Most were macronodular with 85,71%. The response was good or excellent in 81,00% of cases with the first infiltration and rose to 95,00% with the second and third, as required. CONCLUSION. The treatment of lymphangiomas with bleomycin was very effective in the population studied.

Efeito de diferentes intensidades do exercício antagonista no desempenho de repetições dos agonistas em séries pareadas / Effect of different intensities of antagonist exercise on agonist repetitions performance in paired series

O objetivo do presente estudo foi verificar o efeito agudo de diferentes intensidades em séries pareadas agonistas e antagonistas sobre o desempenho de repetições máximas. Participaram de estudo, 12 homens recreacionalmente treinados (idade: 25.83 ± 3.43 anos; peso: 76.33 ± 5.58 kg; altura 1.72 ± 0.04 metros; IMC: 25.95 ± 1.34 kg/m²). Os procedimentos foram separados em cinco sessões: o primeiro encontro constou de anamnese, medidas antropométricas e teste de 10 repetições máximas (RM) nos exercícios rosca bíceps supinada com barra (RB) e tríceps no pulley (TP). Nos demais encontros, os participantes executaram o máximo de repetições no RB com 80% da carga de 10RM após realizarem, de maneira aleatória e em dias separados, um dos 4 protocolos de diferentes intensidades na musculatura antagonista (TP): Protocolo controle (PC), 10 repetições com 40% de 10RM (P40), 10 repetições com 60% de 10RM (P60) e 10 repetições com 80% de 10RM (P80). Para a análise estatística foi realizada uma ANOVA de medidas repetidas e o nível de significância adotado foi de p < 0.05. Os resultados demonstraram que maiores intensidades (P60 = 15.83 ± 0.94 repetições e P80 = 16.42 ± 0.79 repetições) possibilitaram um aumento significativo (p < 0.05) no desempenho de repetições quando comparado ao PC (14.83 ± 0.72 repetições). Além disso, P80 foi também superior ao P40 (15.25 ± 0.97 repetições, p = 0.00), mostrando existir uma dosagem mínima (60% de 10RM) para a melhora de desempenho no método pareado agonista e antagonista. (AU)

The aim of the present study was to verify the acute effect of different intensities of paired agonist and antagonist series on the performance of maximum repetitions. Twelve recreational trained men participated in the study (age: 25.83 ± 3.43 years; weigth: 76.33 ± 5.58 kg; height 1.72 ± 0.04 meters; IMC: 25.95 ± 1.34 kg/m²). The experimental procedure took place over five sessions: the first consisted of anamnesis, anthropometric measurements and a test of 10 maximum repetitions (RM) in the barbell curved supine (RB) and triceps pulley (TP) exercises. nother meetings, the participants performed maximum repetitions in the RB with 80% of the 10RM load after performing, in random order and on separate days, one of the 4 protocols of different intensities in the antagonist musculature (TP): Control protocol (PC), 10 repetitions with 40% of 10RM (P40), 10 repetitions with 60% of 10RM (P60) and 10 repetitions with 80% of 10RM (P80). For the statistical analysis, an ANOVA was performed and the level of significance adopted was p <0.05. The results showed that higher intensities (P60 = 15.83 ± 0.94 repetitions e P80 = 16.42 ± 0.79 repetitions) enabled a significant increase in repetition performance when compared to CP (14.83 ± 0.72 repetitions). In addition, P80 was also superior to P40 (15.25 ± 0.97 repetitions, p = 0.00), showing that there is a minimum dosage (60% of 10RM) to improve performance in the paired agonist and antagonist method. (AU)

Distribución de patrones espásticos en extremidad superior posterior a un daño de motoneurona superior / Distribution of spastic patterns in upper extremity after an upper motor neuron syndrome

ANTECEDENTES: la evidencia sobre personas que presentan daño de motoneurona superior y desarrollan un patrón de espasticidad en extremidad superior (EES) es limitada. Este signo positivo de disfunción o secundario al daño de la motoneurona superior se asocia con pérdida de función y disminución de la independencia, provocando discapacidad y alterando la calidad de vida. OBJETIVO: determinar la distribución de frecuencias de los patrones de EES, muñeca, dedos y pulgar posterior a un daño de motoneurona superior. MÉTODO: diseño descriptivo de corte transversal prospectivo. Se realizó una medición a 206 sujetos pertenecientes a 17 centros de salud, quienes cumplieron con los criterios de inclusión y firmaron el consentimiento. La evaluación incluyó datos clínicos y la evaluación del patrón de EES (Clasificación de Hefter), muñeca, dedos (Zancolli adaptado) y pulgar (Clasificación de House). RESULTADOS: El análisis consideró cada una de las taxonomías de los patrones de EES evaluados (Hefter I a V). La distribución de frecuencias fue investigada mediante la prueba χ2 de bondad de ajuste, seguida de la inspección post hoc de los residuos estandarizados (z) en cada celda. Se identificaron frecuencias significativamente mayores en: el patrón III de extremidad superior, el patrón cubitalizado neutro de muñeca, el patrón del flexor profundo y mixto de Zancolli adaptado, y en los patrones 3, 4 del pulgar. Ninguna taxonomía se asoció al tiempo de evolución y tipo de ACV. CONCLUSIÓN: El estudio aporta evidencia relevante sobre la distribución frecuencia de patrones espásticos, posterior a un daño de motoneurona superior. La información proporcionada busca apoyar el proceso de decisión terapéutica potenciando la recuperación funcional de la extremidad superior.

BACKGROUND: The evidence regarding people who present superior motor neuron damage and develop a pattern of spasticity in the upper limb (SUL) is limited. This positive sign of the superior motor neuron is associated with both the loss of function and the decreased independence, causing disability and altering life quality. OBJECTIVE: to determine the frequency distribution of SUL, wrist, finger and thumb patterns after superior motor neuron damage. METHOD: prospective cross-sectional descriptive design, the sample consisted of 206 patients belonging to 17 health centers, who met the inclusion criteria and signed the informed consent, approved by the committee of ethics. The study considered a measurement, including clinical data and evaluation of the pattern of SUL (Hefter´s classification), wrist, fingers (adapted Zancolli) and thumb (House Classification). RESULTS: The analysis considered each of the taxonomies of evaluated patterns (Hefter´s I-V). Frequency distribution was investigated by χ2 goodness of fit tests, followed by post hoc inspection of standardized residues (z) in each cell. Significantly higher frequencies were identified in the upper limb pattern III, the neutral cubitalized wrist pattern, the adapted Zancolli deep flexor pattern and in the thumb patterns 3, 4. No taxonomy was associated with the evolution time and type of stroke. CONCLUSION: The study provides with relevant scientific evidence regarding the frequency distribution of spasticity patterns after superior motor neuron damage. The information provided can support the therapeutic decision process by enhancing the functional recovery of upper limb.

Comportamento da temperatura da pele no exercício por meio da termografia infravermelha: uma revisão integrativa / Behaviour of skin temperature in exercise via infrared thermography: an integrative review

O objetivo foi realizar uma análise crítica sobre os principais aspectos metodológicos empregados nas pesquisas sobre a resposta da temperatura da pele por termografia infravermelha, bem com seu comportamento durante diferentes formas de exercício, além de descrever as alterações que ocorrem no decorrer do processo de recuperação de até uma hora. Foi realizada uma busca sistemática nas bases de dados MEDLINE/Pubmed, Scielo e Science Direct, utilizando os termos "thermography" and "exercise", no período de janeiro de 2012 a outubro de 2021, sendo incluídos apenas estudos realizados em laboratório. Os principais resultados indicam que a maior parte dos estudos são realizados com homens, adultos, com número amostral restrito. A região de membros inferiores é a mais estudada. O treinamento de força compreendeu 54% dos estudos. Durante exercício progressivo, existe uma clara tendência de redução da temperatura, enquanto no exercício de carga contínua isso somente ocorre nos momentos iniciais. Como conclusão, têm-se uma carência de estudos com mulheres e grupos com faixas etárias extremas, e os procedimentos de análise de imagens não são uniformes entre os estudos. A resposta da temperatura da pele é diferente em função do tipo de exercício realizado (progressivo ou constante), bem como da região exercitada. (AU)

The objective was critically to analyze the main methodological aspects employed in research studies investigating the response of skin temperature to exercise measured via thermography, as well as to describe the behaviour of during and until 1 h after different modes of exercise. A systematic search was performed in the MEDLINE/Pubmed, Scielo, and Science Direct databases using the keywords thermography AND exercise, between January 2012 to October 2021. Only laboratory studies were included. The main results indicate that most studies were performed with male adults, with small sample size. Lower limbs represent the body region more studied. Regarding exercise mode, strength training abranged 54% of studies. During progressive exercise there is clearly a skin temperature reduction, and during continuous exercise of constant load the decrease occur at initial moments of exercise. In conclusion, there is a lack of studies analyzing female and broader age groups, and procedures for analyzing images are not uniform across studies. The skin temperature response to exercise is different according with the mode of exercise performed (constant or progressive load) and exercised body region. (AU)

Efeitos de um macrociclo de treinamento sobre a aptidão física em atletas de futsal feminino durante uma temporada / Effects of a training macrocycle on the physical fitness in female futsal athletes during a season

O objetivo do presente estudo foi analisar os efeitos de macrociclo de treinamento sobre variáveis de aptidão física em atletas semiprofissionais de futsal feminino. Foram avaliadas quatorze atletas (21,1 ± 4,8 anos) semiprofissionais durante 27 semanas de treinamento, correspondentes a: período pré-competitivo e período competitivo. Foram realizadas avaliações antropométricas (massa corporal, estatura e percentual de gordura corporal), testes de potência de membros inferiores (salto vertical e salto horizontal) e membros superiores (arremesso de medicine ball), de força de membros inferiores (1RM de agachamento e legpress) e de membros superiores (supino) e de velocidade (linear e com troca de direção) antes e após o período pré-competitivo e após a primeira fase do período competitivo. ANOVA para medidas repetidas foi utilizada para comparação das variáveis entre os três momentos de avaliação com post hoc de Bonferroni (α = 0,05). Potência de membros inferiores, velocidade linear e força de membros inferiores e superiores (1RM legpress e supino) apresentaram melhora no desempenho nos três momentos (p < 0,001). Percentual de gordura corporal, potência de membros superiores, força de membros inferiores (1RM agachamento) (p < 0,001) e velocidade com troca de direção (p = 0,002) melhoraram o desempenho do momento pré para o momento pós período pré-competitivo e mantiveram este desempenho no momento pós período competitivo. A massa corporal não apresentou diferença significativa entre os momentos. Conclui-se que, os resultados encontrados indicam que as atletas responderam positivamente quanto às variáveis de aptidão física, comprovando a eficácia do treinamento. Ainda, destaca-se a importância do planejamento dos treinos para o sucesso da equipe. (AU)

The aim of the present study was to analyze the macrocycle training effects on physical fitness variables in semiprofessional female futsal athletes. Fourteen semiprofessional athletes (21.1 ± 4.8 years) were measured during 27 weeks of training, corresponding to: precompetitive period and competitive period. The anthropometric variables (body mass, height and body fat percentage), lower limb (vertical and horizontal jump) and upper limb (medicine ball throw) muscle power, lower limb (1RM squat and legpress) and upper limb (1RM bench press) strength and speed (linear and with change of direction) tests were performed pre and post the pre-competitive period and post the first phase of the competitive period. ANOVA for repeated measures plus Bonferroni post hoc were used to compare the variables between the three evaluation moments (α = 0.05). Performance of the lower limb muscle power, linear speed and lower and upper limbs strength (1RM legpress and bench press) were improved at the three moments (p < 0.001). Body fat percentage, upper limb muscle power, lower limb strength (1RM squat) (p <0.001) and speed with change of direction (p = 0.002) improved the performance from pre to post pre-competitive period moment and kept this performance in the post competitive period. Body mass presented no significant difference between the moments. We concluded that the athletes improved physical fitness variables, proving the effectiveness of the training. Still, it is highlighted the importance of the training planning for the team success. (AU)