Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 1.788
Filter
1.
Enferm. foco (Brasília) ; 12(4): 767-772, dez. 2021. tab
Article in Portuguese | LILACS, BDENF | ID: biblio-1353330

ABSTRACT

Objetivos: Identificar, descrever e analisar a Infecção do Trato Urinário e sua recorrência em internação. Caracterizar os aspectos sociodemográficos, laboratoriais e clínicos dos idosos com ITU. Método: Estudo transversal com delineamento descritivo, abordagem quantitativa do tipo analítica, realizada nos prontuários eletrônicos dos idosos que foram internados no ano de 2017 e reinternaram em 2018, na unidade de Geriatria de um hospital de ensino. Na estatística foi usado Teste Exato de Fisher, considerado p<0,05. Resultados: Dos 1.835 prontuários, foram selecionados 550 (29,97%) idosos, destes, foram investigados 121 (22%) com ITU. A maioria foi do sexo masculino com idade entre 80 e 89 anos. Dentre eles, 51,2% usaram algum tipo de sonda vesical e 52,9% usaram frauda. Os exames alterados foram os de creatinina, Proteina-C-Reativa, urina I (proteínas e leucócitos), além de urocultura positiva para Escherichia Coli. Dos 121 pacientes investigados, 50,4% tiveram reinternação por Infecção urinária, destes, 42,6% morreram e, dos que não tiveram recorrência, foram 18,3% óbitos (p= 0,00054).Conclusão: O idoso tem predisposição maior para adquirir infeção urinária, além de apresentar recidivas, principalmente os que fazem uso de sonda vesical e fralda, o que ocasiona aumento da frequência de hospitalizações, do estadiamento no hospital e da mortalidade. (AU)


Objective: Analyze the Urinary Tract Infection and its recurrence in hospitalization in the elderly, characterizing the sociodemographic, laboratory and clinical aspects. Methods: Cross sectional study with descriptive design, quantitative approach of an analytical type, carried out on the electronic medical records of the elderly who were hospitalized in 2017 and readmitted in 2018, in the Geriatrics unit of a teaching hospital. Fisher's exact test was used in statistics, considered p <0.05. Results: Of the 1,835 records, 550 (29.97%) elderly were selected, of these, 121 (22%) with Urinary Tract Infection were investigated. The majority were male aged between 80 and 89 years. Among them, 51.2% used some type of bladder catheter and 52.9% used fraud. The altered tests were those of creatinine, C-Reactive Protein, urine I (proteins and leukocytes), in addition to positive urine culture for Escherichia Coli. Of the 121 patients investigated, 50.4% had readmission for urinary tract infection, of these, 42.6% died and, of those who did not have recurrence, 18.3% died (p = 0.00054). Conclusion: The elderly is predisposed greater to acquire urinary infection, in addition to relapses, especially those who use a bladder catheter and diaper, which causes an increase in the frequency of hospitalizations, hospital stay and mortality. (AU)


Objetivo: Analizar la Infección del Tracto Urinario y su recurrencia en la hospitalización del anciano, caracterizando los aspectos sociodemográficos, de laboratorio y clínicos. Métodos: Estudio transversal con diseño descriptivo, abordaje cuantitativo de tipo analítico, realizado sobre la historia clínica electrónica de los ancianos que fueron hospitalizados en 2017 y readmitidos en 2018, en la unidad de Geriatría de un hospital universitario. En estadística se utilizó la prueba exacta de Fisher, considerada p <0,05. Resultados: De las 1.835 historias clínicas, se seleccionaron 550 (29,97%) ancianos, de estos se investigaron 121 (22%) con Infección del Tracto Urinario. La mayoría eran hombres de entre 80 y 89 años. Entre ellos, el 51,2% utilizó algún tipo de sonda vesical y el 52,9% utilizó fraude. Las pruebas alteradas fueron las de creatinina, proteína C reactiva, orina I (proteínas y leucocitos), además de urocultivo positivo para Escherichia Coli. De los 121 pacientes investigados, el 50,4% tuvo reingreso por infección del tracto urinario, de estos, el 42,6% falleció y, de los que no presentaron recidiva, falleció el 18,3% (p = 0,00054). Conclusión: Los ancianos tienen mayor predisposición a adquirir urinaria infección, además de recaídas, especialmente en quienes utilizan sonda vesical y pañal, lo que provoca un aumento en la frecuencia de hospitalizaciones, estancia hospitalaria y mortalidad. (AU)


Subject(s)
Old Age Assistance , Recurrence , Urinary Tract , Cross Infection
3.
Rev. enferm. Inst. Mex. Seguro Soc ; 29(3): 150-159, 04-oct-2021. tab
Article in Spanish | LILACS, BDENF | ID: biblio-1357925

ABSTRACT

Introducción: las infecciones de las vías urinarias relacionadas con la instalación de catéter vesical son de las infecciones asociadas a la atención sanitaria más comunes en México y el mundo. Representan un riesgo latente para el desarrollo de complicaciones y pueden ocasionar la muerte. Objetivo: analizar los factores de riesgo que se asocian directamente a la infección del tracto urinario en la instalación del catéter vesical. Metodología: estudio observacional, descriptivo y transversal, con muestra de 90 pacientes de un hospital de segundo nivel de atención en el que se identificaron los factores de riesgo de infección de vías urinarias asociadas a la instalación de sonda vesical. Resultados: se observó un tipo de cumplimiento de los indicadores de calidad durante la instalación de sonda vesical con frecuencia en el 52.22% de los participantes. Un tipo de cumplimiento con frecuencia en el 48.90% de los participantes durante el mantenimiento de la sonda vesical, y un tipo de cumplimiento con frecuencia del 47.78% al momento del retiro de la sonda. Los principales factores de riesgo identificados asociados a la infección del tracto urinario fueron: a) que la sonda sea instalada por un médico interno, b) una estancia mayor a 3 días en urgencias y c) que la sonda sea instalada por una enfermera general. Conclusiones: se encontraron indicadores de cumplimiento cercano al 50%, lo que se considera muy bajo en la medición de los indicadores de calidad durante la instalación, mantenimiento y retiro de la sonda vesical, incluso estos están por debajo del porcentaje nacional.


Introduction: Urinary tract infections related to the installation of a bladder catheter are the most common infections associated with health care in Mexico and the world. They represent a latent risk for the development of complications and can cause death. Objective: To analyze the risk factors that are directly associated with urinary tract infection in the installation of the bladder catheter. Methods: Observational, descriptive and cross-sectional study; with a sample of 90 patients from a second-level care hospital in which the risk factors for urinary tract infection associated with the installation of a urinary catheter were identified. Results: A type of compliance with the quality indicators was observed during the urinary catheter installation with a frequency of 52.22% of the participants. A type of compliance with a frequency of 48.90% of the participants during the maintenance of the urinary catheter, and a type of compli- ance with a frequency of 47.78% at the time of catheter removal. The main risk factors identified associated with urinary tract infection were: a) that the catheter is installed by an intern, b) a stay of more than 3 days in the emergency room, and c) that the catheter is installed by a general nurse. Conclusions: Compliance indicators were found close to 50%, which is considered very low in the measurement of quality indicators during the installation, maintenance and removal of the urinary catheter, even these are below the national percentage.


Subject(s)
Humans , Urinary Tract , Urinary Tract Infections , Cross-Sectional Studies , Urinary Catheters , Secondary Care , Mexico
4.
Fisioter. Bras ; 22(3): 442-455, Jul 15, 2021.
Article in Portuguese | LILACS | ID: biblio-1290536

ABSTRACT

Introdução: A fibromialgia é uma síndrome crônica, com etiologia desconhecida, frequente em mulheres e com sintomas que afetam a qualidade de vida. Tem se discutido que essa condição afete inclusive a musculatura do assoalho pélvico. Objetivo: Verificar o conhecimento a respeito do períneo, a presença de sintomas de perdas urinárias e o nível de satisfação sexual em mulheres fibromiálgicas. Métodos: Participaram dessa abordagem 7 fibromiálgicas atendidas semanalmente pela fisioterapia. Para avaliação inicial, utilizamos um Questionário de Consciência Perineal e o Índice de Satisfação Sexual Feminina (FSFI). Durante os dois meses de intervenção, foram realizadas 2 palestras educativas e 8 encontros para a realização de exercícios perineais. Depois da intervenção, o FSFI foi aplicado novamente e os dados foram analisados por estatística simples. Resultados: As participantes demonstraram conhecer a localização das estruturas do sistema urinário, porém 4 das mulheres (57,1%) relataram não saber contrair a musculatura do assoalho pélvico. Todas relataram urgência miccional, raras perdas urinárias ao esforço e insatisfação sexual, antes da intervenção melhorando na reavaliação. Conclusão: As participantes pouco conhecem sobre a musculatura do assoalho pélvico, sua contração adequada e a atuação da fisioterapia nessa condição. A satisfação sexual encontrou-se prejudicada inicialmente apresentando melhora após as intervenções. (AU)


Introduction: Fibromyalgia is a chronic syndrome, with unknown etiology, common in women and with symptoms that affect quality of life. It has been argued that this condition affects even the pelvic floor musculature. Objective: To verify the knowledge about the perineum, the presence of symptoms of urinary loss and the level of sexual satisfaction in fibromyalgia women. Methods: Seven fibromyalgia patients attended weekly by physical therapy participated in this approach. For initial assessment, we used Perineal Awareness Questionnaire and Female Sexual Satisfaction Index (FSFI). During two months of intervention, 2 educational lectures and 8 meetings were held to perform perineal exercises. After intervention, FSFI was applied again, and the data were analyzed using simple statistics. Results: The participants demonstrated to know the location of the structures of the urinary system, however 4 of the women (57.1%) reported not knowing how to contract the pelvic floor muscles. All of them reported urinary urgency, rare urinary losses on exertion and sexual dissatisfaction, before the intervention, improving the reassessment. Conclusion: The participants know little about the musculature of the pelvic floor, its adequate contraction, and the role of physical therapy in this condition. Sexual satisfaction was initially impaired, showing improvement after the interventions. (AU)


Subject(s)
Humans , Female , Fibromyalgia , Physical Therapy Modalities , Orgasm , Quality of Life , Urinary Tract , Pelvic Floor , Consciousness
5.
Cambios rev. méd ; 20(1): 10-14, 30 junio 2021. tabs.
Article in Spanish | LILACS | ID: biblio-1292684

ABSTRACT

INTRODUCCIÓN. Las infecciones del tracto urinario son causa de mayor morbilidad en la población adulta y afectan con frecuencia a la mujer. Al ser un problema prevalente, fue fundamental realizar estudios sobre perfiles de susceptibilidad locales para establecer medidas de vigilancia y control de uso de antibióticos. OBJETIVO. Determinar el perfil de farmacorresistencia microbiana en adultos con infección del tracto urinario. MATERIALES Y MÉTODOS. Estudio descriptivo, transversal. La población fue de 437 urocultivos y una muestra de 176 positivos con su antibiograma, realizados en el laboratorio del Hospital Básico de Sangolquí entre enero de 2017 hasta abril de 2018. Los criterios de inclusión fueron: pacientes mayores de 15 años de edad de ambos sexos, ambulatorios y hospitalizados, que presentaron urocultivos positivos definidos por una cuenta mayor a 100 000 Unidades Formadoras de Colonia. RESULTADOS. Del 40,27% (176; 437) de urocultivos positivos, la bacteria aislada con frecuencia fue Escherichia coli. 69,31% (122; 176), con resistencia a ampicilina 77,97% (92; 118), trimetropim-sulfametoxazole 62,26% (66; 106), norfloxacino 37,50% (42; 112), ciprofloxacino 35,65 % (41; 115), ampicilina/sulbactam 32,20% (38; 118) y con susceptibilidad a: fosfomicina, ceftriaxona, amikacina y nitrofurantoina. CONCLUSIÓN. Se determinó el perfil de farmacorresistencia microbiana en adultos con infección del tracto urinario; donde Escherichia coli. fue aislada con frecuencia, con susceptibilidad favorable para nitrofurantoína y fosfomicina.


INTRODUCTION. Urinary tract infections are the cause of greater morbidity in the adult population and it often affects women. As it is a prevalent problem, it was essential to carry out studies on local susceptibility profiles to establish surveillance measures and control of antibiotic use. OBJECTIVE. To determine the microbial drug resistance profile in adults with urinary tract infection. MATERIALS AND METHODS. Descriptive, cross-sectional study. The population was 437 urine cultures and a sample of 176 positive with their antibiogram, carried out in the laboratory of the Hospital Básico de Sangolquí between january 2017 and april 2018. Inclusion criteria were: patients older than 15 years of age of both sexes, ambulatory and hospitalized, who presented positive urine cultures defined by a count greater than 100 000 Colony Forming Units. RESULTS. Of the 40,27% (176; 437) of positive urine cultures, the bacterium frequently isolated was Escherichia coli. 69,31% (122; 176), with resistance to ampicillin 77,97% (92; 118), trimethoprim-sulfamethoxazole 62,26% (66; 106), norfloxacin 37,50% (42; 112), ciprofloxacin 35,65% (41; 115), ampicillin / sulbactam 32,20% (38; 118) and with susceptibility to: fosfomycin, ceftriaxone, amikacin and nitrofurantoin. CONCLUSION. The microbial drug resistance profile was determined in adults with urinary tract infection; where Escherichia coli. was frequently isolated, with favorable susceptibility to nitrofurantoin and fosfomycin.


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged , Young Adult , Urinary Tract , Urinary Tract Infections , Drug Resistance, Microbial , Anti-Bacterial Agents , Staphylococcus , Bacteriuria , Ampicillin Resistance , Microbial Sensitivity Tests , Drug Resistance, Bacterial , Escherichia coli
6.
Infectio ; 25(1): 71-74, ene.-mar. 2021. graf
Article in Spanish | LILACS, COLNAL | ID: biblio-1154407

ABSTRACT

Resumen La bacteremia por Streptococcus gordonii es infrecuente. Su aislamiento en hemocultivo traduce alta significancia clínica y debe dirigir el abordaje diagnóstico hacia la búsqueda de entidades subyacentes como neoplasias hematológicas, cardiopatías valvulares, neumonía, alteraciones estructurales de cabeza y cuello, inmunosupresión, y otras condiciones asociadas. No se han identificado reportes en pacientes con neoplasia de vías urinarias como posible condicionante de bacteremia por este agente. Se describe el caso de un paciente que, durante el estudio de bacteremia por este microorganismo, fue diagnosticado de carcinoma urotelial de alto grado.


Abstract Streptococcus gordonii bacteremia is rare. Its isolation in blood culture translates into high clinical significance and the diagnostic approach should be directed towards the search for underlying entities such as hematologic malignancies, valvular heart disease, pneumonia, structural changes of the head and neck, immunosuppression and other related conditions. No reports have been identified in patients with urinary tract neoplasia as a possible condition of bacteremia by this agent. The case of a patient who was diagnosed with high-grade urothelial carcinoma during the study of bacteremia by this microorganism is described.


Subject(s)
Humans , Male , Aged, 80 and over , Carcinoma , Bacteremia , Streptococcus gordonii , Urinary Tract , Immunosuppression , Sepsis , Hematologic Neoplasms , Neoplasms
7.
Rev. cuba. invest. bioméd ; 40(1): e599, ene.-mar. 2021. tab
Article in Spanish | LILACS, CUMED | ID: biblio-1289439

ABSTRACT

Introducción: Las infecciones de tracto urinario se encuentran entre las infecciones de mayor prevalencia en la parte clínica. Son un problema de salud global y se pueden presentar con o sin síntomas. Los agentes bacterianos aislados en mayor frecuencia son Escherichia coli, Klebsiella spp y Proteus spp. Objetivo: Caracterizar las infecciones de tracto urinario producidas por enterobacterias productoras de betalactamasas de espectro extendido en pacientes hospitalizados, Lima 2016-2018. Métodos: Se realizó un estudio descriptivo en 2 instituciones prestadoras de salud, en Lima, Perú, durante el periodo 2016-2018, a partir de los aislamientos de patógenos blee asociados a infecciones de tracto urinario. Se tuvieron en cuenta variables sociodemográficas, enfermedades asociadas, agentes aislados, tratamiento y respuesta clínica. Resultados: Se obtuvo un registro de 117 pacientes, con edad promedio de 58,18 ± 11,8 años; 65,0 por ciento fueron mujeres y 89,74 por ciento provenían del área urbana de Lima. Las enfermedades asociadas más frecuentes fueron diabetes (39,3 por ciento) y enfermedad renal moderada o grave (12,8 por ciento), con índice de Charlson medio de 2,70 ± 1,21. Los agentes aislados más comunes fueron Escherichia coli (92,3 por ciento), Klebsiella spp (6,0 por ciento) y Proteus spp (1,7 por ciento). Los tratamientos empíricos usados fueron ampicilina/sulbactam (18,9 por ciento), ciprofloxacino (49,6 por ciento) y nitrofurantoína (16,7 por ciento). El 49,2 por ciento de los pacientes recibió tratamiento dirigido, 22,8 por ciento ertapenem y 13,9 por ciento piperacilina/tazobactam. Conclusiones: Las personas con diabetes y enfermedad renal son un grupo vulnerable a las infecciones de tracto urinario. El agente causal aislado en mayor frecuencia fue Escherichia coli blee+. Los tratamientos de inicio luego de la identificación clínica de la infección urinaria fueron ciprofloxacino y cefalosporinas. Una vez obtenidos los resultados microbiológicos se modificó el tratamiento antibiótico a carbapenémicos y penicilinas. La revaloración de los antibióticos usados en pacientes con enfermedades asociadas es importante para el éxito del tratamiento(AU)


Introduction: Urinary tract infections are among the most prevalent infections in clinical practice. They are a global health problem and may present with or without symptoms. The bacterial agents most commonly isolated are Escherichia coli, Klebsiella spp. and Proteus spp. Objective: Characterize urinary tract infections caused by extended-spectrum betalactamase producing enterobacteria in hospitalized patients from Lima in the period 2016-2018. Methods: A descriptive study was conducted at two health institutions from Lima, Peru, in the period 2016-2018, based on isolation of ESBL pathogens associated to urinary tract infections. Attention was paid to sociodemographic variables, associated conditions, agents isolated, treatment and clinical response. Results: A sample was selected of 117 patients; mean age was 58.18 ± 11.8 years; 65.0 percent were women and 89.74 percent came from the urban area of Lima. The most common associated conditions were diabetes (39.3 percent) and moderate or serious kidney disease (12.8 percent), with a mean Charlson index of 2.70 ± 1.21. The most common isolated agents were Escherichia coli (92.3 percent), Klebsiella spp. (6.0 percent and Proteus spp. (1.7 percent). The empirical treatments used were ampicillin/sulbactam (18.9 percent), ciprofloxacin (49.6 percent) and nitrofurantoin (16.7 percent). 49.2 percent of the patients received targeted treatment, 22.8 percent ertapenem and 13.9 percent piperacillin/tazobactam. Conclusions: People with diabetes and kidney disease are vulnerable to urinary tract infections. The causative agent most commonly isolated was ESBL Escherichia coli. The initial treatments indicated after clinical identification of urinary infection were ciprofloxacin and cephalosporins. When microbiological results were obtained, antibiotic therapy was changed to carbapenems and penicillins. Reassessment of the antibiotics used in patients with associated conditions is important for the success of the treatment(AU)


Subject(s)
Humans , Male , Female , Urinary Tract , Carbapenems , Kidney Diseases/drug therapy , Anti-Bacterial Agents
9.
Article in English | LILACS | ID: biblio-1359846

ABSTRACT

Introduction: Urinary tract infections (UTI) are common in women and can cause systemic repercussions. In pregnant women, for example, the occurrence of UTI or asymptomatic bacteriuria (AB) can lead to premature birth and fetal death. The generalized immune depletion caused by HIV is related to the exacerbation of infections, and may be related to UTI. Objective: The objective of this review was to evaluate the characteristics of UTI in pregnant and non-pregnant HIV-positive women as well as the factors that interfere in its occurrence. Methods: By searching the databases PubMed, Web of Science, Scielo and Lilacs, we selected eleven articles that correlated UTI and HIV infection in women. Results: Our analysis showed that HIV-positive pregnant women have a higher predisposition to UTI than HIV-negative ones. The Viral Load (VL) is directly related to UTI and AB in HIV-positive nonpregnant women. TCD4 lymphocyte levels (TCD4) lower than 200 cells/mL and VL over 10,000 copies/mL are correlated with higher UTI and AB rates in HIV-positive pregnant women. There is a tendency for greater variability of pathogens in HIV-positive women and a predisposition to higher rates of antibiotic resistance in HIV-positive pregnant women. Conclusion: HIV-positive pregnant women have higher predisposition to urinary tract infection and its incidence is correlated with a high viral load and a low TCD4 count.


Introdução: As infecções do trato urinário (ITU) são comuns em mulheres e podem causar repercussões sistêmicas. Em mulheres grávidas, por exemplo, a ocorrência de ITU ou bacteriúria assintomática (BA) pode levar ao nascimento prematuro e à morte fetal. A depleção imunológica generalizada causada pelo HIV está relacionada à exacerbação de infecções e pode estar relacionada à ITU. Objetivo: O objetivo desta revisão foi avaliar as características da ITU em gestantes e não gestantes HIV-positivas, bem como os fatores que interferem na sua ocorrência. Métodos: Por meio de busca nas bases de dados PubMed, Web of Science, SciELO e LILACS, foram selecionados 11 artigos que correlacionavam ITU a infecção pelo HIV em mulheres. Resultados: Nossa análise mostrou que gestantes soropositivas têm maior predisposição à ITU do que gestantes soronegativas. A carga viral está diretamente relacionada a ITU e BA em mulheres não grávidas HIV-positivas. Os níveis de linfócitos TCD4 (TCD4) abaixo de 200 células/mL e a carga viral acima de 10.000 cópias/mL estão correlacionados a maiores taxas de ITU e BA em mulheres grávidas HIV-positivas. Há uma tendência para maior variabilidade de patógenos em mulheres HIV-positivas e uma predisposição para maiores taxas de resistência a antibióticos em mulheres grávidas HIV-positivas. Conclusão: Gestantes HIVpositivas apresentam maior predisposição à infecção do trato urinário e sua incidência está correlacionada com alta carga viral e baixa contagem de TCD4.


Subject(s)
Humans , Urinary Tract Infections , Women , Pregnant Women , Urinary Tract , HIV , HIV Seropositivity
10.
Rev. Méd. Paraná ; 79(1): 91-93, 2021.
Article in Portuguese | LILACS | ID: biblio-1282487

ABSTRACT

A herniação do ureter é uma condição médica extremamente rara e geralmente ocorre após transplantes ou ptose renal. A maioria dos casos relatados são identificados no momento da exploração cirúrgica para correção de hérnia inguinal, ou posteriormente como resultado de uma lesão operatória. Os pacientes comumente são assintomáticos até o agravamento do quadro, a idade média afetada é entre a quinta e sexta década de vida. O relato de caso destaca a importância de um diagnóstico precoce de um fenômeno incomum para evitar possíveis complicações. A herniação do ureter é uma causa importante de complicações no enxerto após transplantes renais, os sintomas dependem do grau de obstrução ureteral, localização e da presença de agravos. O procedimento de correção geralmente consiste em hernioplastia, inserção de stent e, em alguns casos, até mesmo ressecção do ureter e reanamastose. Devido ao risco de uropatia obstrutiva o tratamento deve ser realizado com cautela


Ureter herniation is an extremely rare medical condition and usually occurs after transplants or renal ptosis. Most of the reported cases are identified at the time of surgical exploration to correct an inguinal hernia, or later as a result of an operative injury. Patients are usually asymptomatic until the condition worsens, the average age affected is between the fifth and sixth decade of life. The case report highlights the importance of an early diagnosis of an unusual phenomenon to avoid possible complications. Herniation of the ureter is an important cause of graft complications after kidney transplants, the symptoms depend on the degree of ureteral obstruction, location, and the presence of injuries. The correction procedure usually consists of hernioplasty, stent insertion, and, in some cases, even resection of the ureter and resuscitation. Due to the risk of obstructive uropathy, treatment should be carried out with caution


Subject(s)
Humans , Urethra , Urinary Tract , Tomography, X-Ray Computed , Hernia , Diagnosis
11.
Rev. Pesqui. (Univ. Fed. Estado Rio J., Online) ; 13: 757-762, jan.-dez. 2021. graf, tab
Article in English, Portuguese | LILACS, BDENF | ID: biblio-1222817

ABSTRACT

Objective:To identify the prevalence of klebsiella pneumoniae and to analyze the factors related to the infection by this bacterium in a private hospital in northeastern Brazil. Method: descriptive retrospective documentary study, carried out with patients who developed infection in the year 2017 (n: 64). Sociodemographic and infection information was collected. The data was processed in SPSS 20.0. The project was approved by the ethics committee. Results: the most prevalent topographic site was the urinary tract (34; 56.7%). the main risk factor for triggering klebsiella pneumoniae infection was the use of mechanical ventilation, presenting a risk of 43.8% for the appearance of infections by this microorganism. Higher resistance was found for the piperacillin / tazobactam 52 antimicrobial (82.5%). Conclusion: because of the high resistance to antibiotics and the great potential of klebsiella contamination, measures should be taken to minimize the high level of contamination and, especially, the negative prognosis for the patient


Objetivo: Identificar a prevalência de Klebsiella pneumoniae e analisar os fatores relacionados à infecção por essa bactéria em hospital privado do nordeste brasileiro. Método: estudo descritivo retrospectivo documental, realizado com pacientes que desenvolveram infecção no ano de 2017 (n:64). Coletou-se informações sociodemográficas e referentes a infecção. Os dados foram processados no SPSS 20.0. O projeto foi aprovado pelo comitê de ética. Resultados: o sítio topográfico mais prevalente foi o trato urinário (34;56,7%). o principal fator de risco para desencadear infecção por Kebsiella pneumoniae foi a utilização de ventilação mecânica, apresentando risco de 43,8% para o aparecimento de infecções por esse microrganismo. Maior resistência foi encontrada para o antimicrobiano piperacilina/tazobactam 52 (82,5%). Conclusão: pela alta resistência aos antibióticos e o grande potencial de contaminação da klebsiella, medidas devem ser adotadas para minimizar o alto nível de contaminação e, principalmente do prognóstico negativo para paciente


Objetivo: Identificar la prevalencia de klebsiella pneumoniae y analizar los factores relacionados con la infección por esta bacteria en un hospital privado en el noreste de Brasil. Método: estudio descriptivo retrospectivo, realizado con pacientes que desarrollaron infección en el año 2017 (n: 64). Se recogió información sociodemográfica y de infección. Los datos fueron procesados en SPSS 20.0. El proyecto fue aprobado por el comité de ética. Resultados: el sitio topográfico más prevalente fue el tracto urinario (34; 56,7%). El principal factor de riesgo para desencadenar la infección por Klebsiella pneumoniae fue el uso de ventilación mecánica, que presenta un riesgo del 43.8% por la aparición de infecciones por este microorganismo. Se encontró una mayor resistencia para el antimicrobiano piperacilina / tazobactam 52 (82.5%). Conclusión: debido a la alta resistencia a los antibióticos y al gran potencial de contaminación por klebsiella, se deben tomar medidas para minimizar el alto nivel de contaminación y, especialmente, el pronóstico negativo para el paciente


Subject(s)
Humans , Male , Female , Infection Control/statistics & numerical data , Klebsiella pneumoniae/drug effects , Anti-Infective Agents/therapeutic use , Anti-Bacterial Agents/therapeutic use , Piperacillin/therapeutic use , Urinary Tract/microbiology , Prevalence , Risk Factors , Hospitals, Private , Tazobactam/therapeutic use
12.
Ciênc. cuid. saúde ; 20: e57337, 2021. tab, graf
Article in Portuguese | LILACS, BDENF | ID: biblio-1356118

ABSTRACT

RESUMO Introdução: A Disfunção do Trato Urinário Inferior (DTUI) é uma complicação do Diabetes Mellitus (DM) e embora cause impacto negativo na qualidade de vida, não é contemplada nos programas de atenção a essa população. Objetivo: Levantar a ocorrência de DTUI em uma população com DM Tipo 2e avaliar sua associação com a história clínica. Método: Estudo transversal. Entrevista com 60 pacientes de um centro privado de DM por meio de instrumento contendo dados sociodemográficos, clínicos e sintomas de armazenamento e esvaziamento vesical apresentados nos últimos 30 dias. Análise estatística por meio do programa computacional IBM SPSS Statistics, v20.0. Resultados: Amostra predominantemente aposentada com alta escolaridade, bom padrão alimentar e intestinal, sedentária, obesa ou em sobrepeso, com taxas de hemoglobina glicada elevadas. Do total, 25% apresentavam incontinência urinária aos esforços, 60% pelo menos um sintoma de bexiga hiperativa, 41,7% pelo menos um sintoma de esvaziamento vesical incompleto, 70,1% pelo menos um sintoma de DTUI. Foi encontrada associação entre os sintomas urinários e o tempo de diagnóstico de DM. Conclusão: A população com DM tipo 2 apresenta alta ocorrência de DTUI, com predominância de sintomas de bexiga hiperativa, associada ao tempo de diagnóstico de DM.


RESUMEN Introducción: la Disfunción del Tracto Urinario Inferior (DTUI) es una complicación de la Diabetes Mellitus (DM) y aunque cause impacto negativo en la calidad de vida, no es contemplada en los programas de atención a esa población. Objetivo: obtener la incidencia de DTUI en una población con DM Tipo 2 y evaluar su asociación con la historia clínica. Método: estudio transversal. Entrevista con 60 pacientes de un centro privado de DM a través de un instrumento que contiene datos sociodemográficos, clínicos y síntomas de almacenamiento y vaciado vesical presentados en los últimos 30 días. Análisis estadístico por medio del programa computacional IBM SPSS Statistics, v20.0. Resultados: muestra predominantemente jubilada con alta escolaridad, buen patrón alimentario e intestinal, sedentaria, obesa o en sobrepeso, con niveles de hemoglobina glicosilada elevados. Del total, el 25% presentaba incontinencia urinaria a los esfuerzos, el 60% por lo menos un síntoma de vejiga hiperactiva, el 41,7% por lo menos un síntoma de vaciado vesical incompleto, el 70,1% por lo menos un síntoma de DTUI. Se encontró asociación entre los síntomas urinarios y el tiempo de diagnóstico de DM. Conclusión: la población con DM tipo 2 presenta alta incidencia de DTUI, con predominancia de síntomas de vejiga hiperactiva, asociada al tiempo de diagnóstico de DM.


ABSTRACT Introduction: Lower Urinary Tract Symptoms(LUTS) are a complication of Diabetes Mellitus (DM) and although it negatively impactsthe quality of life, it is not considered in care programs for this population. Objective: To survey the occurrence of LUTS in a population with Type 2 DM and assess its association with clinical history. Method: Cross-sectional study. Interview with 60 patients from a private DM clinic using a tool with sociodemographic and clinical data and symptoms of bladder storage and voiding in the last 30 days. Statistical analysis was performed using the computer program IBM SPSS Statistics, v20.0. Results: Most of the participants were retired with high education, good dietary, and intestinal pattern, sedentary, obese, or overweight, with high glycated hemoglobin rates. Of the total, 25% had stress urinary incontinence, 60% had at least one symptom of overactive bladder, 41.7% had at least one symptom of incomplete bladder voiding, 70.1% had at least one LUTsymptom. An association was found between urinary symptoms and time since DM diagnosis. Conclusion: The population with type 2 DM has a high occurrence of LUTS, with a predominance of symptoms of overactive bladder, associated with the time of DM diagnosis.


Subject(s)
Humans , Male , Female , Urinary Tract , Diabetes Mellitus, Type 2 , Patients , Quality of Life , Urinary Incontinence , Urinary Bladder , Glycated Hemoglobin A , Urinary Retention , Nursing , Diet , Disease Prevention , Overweight , Urinary Bladder, Overactive , Sedentary Behavior
13.
Rev. cient. Esc. Univ. Cienc. Salud ; 7(2): 63-64, jun.-dic. 2020. ilus.
Article in Spanish | LILACS, BIMENA | ID: biblio-1343967

ABSTRACT

Imagen: Signo de la Cobra (flecha #1) hallazgo compatible con ureterocele, y en su interior imagen hiperecoica con sombra acústica posterior en relación con cálculo (flecha #2)...(AU)


Subject(s)
Humans , Male , Ureterocele/diagnostic imaging , Gallstones , Ureter , Urinary Tract
14.
Infectio ; 24(4): 217-223, oct.-dic. 2020. tab, graf
Article in Spanish | LILACS, COLNAL | ID: biblio-1114872

ABSTRACT

Resumen Candida spp. es un agente etiológico importante en infecciones del tracto urinario, principalmente en población con terapia antimicótica de amplio espectro y con catéteres urinarios. Candida albicans es la especie más frecuente, pero otras especies han surgido como patógenos emergentes. En este trabajo se recolectaron aislamientos de Candida spp. de urocultivos de pacientes que consultaron en Dinamica IPS entre enero 2016 y noviembre 2017. Para estimar la frecuencia de las especies y observar los patrones de sensibilidad, se realizó la identificación fenotípica y su perfil de sensibilidad con el sistema comercial Vitek 2® (BioMérieux, Inc.), adicionalmente se evaluaron mediante análisis de las secuencia y filogenética ITS1-5.8S-ITS2. En el estudio se incluyeron 78 aislamientos de Candida spp. Las frecuencias de especies de Candida identificadas empleando las herramientas moleculares fueron: C. albicans (38,5%), C. tropicalis (23,1%), C. glabrata (21,8%), C. parapsilosis (10,3%), C. metapsilosis y C. krusei (2,5%) y C. guillermondi (1,3%). La identificación por métodos moleculares y por el sistema Vitek 2 fue: C. albicans (93,3%), C. glabrata (94,1%), C. tropicalis (83,3%), C. parapsilosis (75%) C. guilliermondii y C. krusei (100%). La sensibilidad de todos los aislamientos al fluconazol fue 93,6%.


Abstract Candida spp is an important etiologic agent in urinary tract infections, mainly in patients in broad-spectrum antifungal therapy, with urinary catheters. Candida albicans is the most frequent specie; but other species have arised as emerging pathogens. In this study, isolates of Candida spp. of urine cultures from patients who consulted in Dinamica IPS between January 2016 and November 2017 were evaluated. To estimate the frequency of the species and to observe the sensitivity patterns, the phenotypic identification and its sensitivity profile was performed employed the Vitek 2® commercial system. (BioMérieux, Inc) In addition the isolates were evaluated by sequence analysis and phylogenetics ITS1-5.8S-ITS2. This study included 78 isolates of Candida spp. The frequencies of Candida species identified using the molecular tools were: C. albicans (38.5%), C. tropicalis (23.1%), C. glabrata (21.8%), C. parapsilosis (10.3%), C. guillermondi (1.3%) and C. metapsilosis and C. krusei (2.5%). The identification by molecular methods and by Vitek 2 system were: C. albicans (93.3%), for C. glabrata (94.1%), C. tropicalis (83.3%), C. parapsilosis (75%) and 100% for C. guilliermondii and C. krusei.. fluconazole sensitivity of all isolates was 93.6%


Subject(s)
Humans , Male , Female , Child , Adolescent , Adult , Middle Aged , Aged , Candida , Diagnostic Techniques, Urological , Candida parapsilosis , Laboratories , Urinary Tract , Urinary Tract Infections , Candida albicans , Fluconazole , Sequence Analysis , Urinary Catheters , Infections
15.
Bol. méd. postgrado ; 36(2): 43-47, dic.2020. tab, graf
Article in Spanish | LILACS, LIVECS | ID: biblio-1117899

ABSTRACT

La uroflujometría es un estudio no invasivo del tracto urinario inferior que entrega información objetiva del flujo urinario y es ampliamente recomendado por las guías europeas en el estudio de pacientes con sintomatología urinaria baja. Se realizó un estudio descriptivo transversal cuyo propósito fue describir el uso de la uroflujometría en el estudio de síntomas del tracto urinario bajo en pacientes masculinos que acudieron a la consulta de Servicio de Urología del Hospital Central Universitario Dr. Antonio María Pineda de la ciudad de Barquisimeto, estado Lara durante el lapso 2018- 2019. La muestra estuvo conformada por 150 pacientes. Los resultados indican que el 62% de la muestra corresponde a pacientes entre 60 y 70 años de edad de los cuales 52% manifestaron síntomas urinarios leves. La uroflujometría evidenció que 56% de los pacientes tienen un flujo máximo entre 10 y 20 ml/seg lo cual sugiere una probable obstrucción al flujo de salida; 78% de los pacientes presentan un flujo promedio entre 0 a 10 ml/seg. El 53% de los pacientes mostró un volumen de vaciado < 300 ml y 49% un tiempo de flujo máximo entre 30 y 50 segundos. En conclusión, la uroflujometría es un examen simple y rápido que proporciona información útil sobre la salud de las vías urinarias inferiores(AU)


Uroflowmetry is a non-invasive study of the lower urinary tract that provides objective information on urinary flow and is widely recommended by European guidelines for the study of patients with lower urinary tract symptoms. We performed a cross-sectional descriptive study to describe the use of uroflowmetry for the study of lower urinary tract symptoms in males who attended the Servicio de Urología of the Hospital Central Universitario Dr. Antonio María Pineda (Barquisimeto, Lara state) during the 2018- 2019 period. The sample was made up of 150 males. The results show that 62% of the sample included males between 60 and 70 years old and 52% complained of mild urinary symptoms. Uroflowmetry results showed that 56% of patients had a maximum flow between 10 and 20 ml/sec suggestive of urinary tract obstruction; 78% had an average flow between 0 and 10 ml/sec while 53% had a micturition volume < 300 ml and 49% had a maximum flow time between 30 and 50 seconds. Uroflowmetry is a simple and fast test which provides useful information about the health of lower urinary tract(AU)


Subject(s)
Humans , Male , Middle Aged , Aged , Urethral Obstruction , Urinary Tract , Prostatism/diagnostic imaging , Conservative Treatment/methods , Urination , Urologic Diseases , Ultrasonography
16.
Rev. cuba. pediatr ; 92(4): e977, oct.-dic. 2020. tab, graf
Article in Spanish | LILACS, CUMED | ID: biblio-1144516

ABSTRACT

Introducción: Las malformaciones congénitas del riñón y del tracto urinario representan entre 20 y 30 por ciento de todas las malformaciones reconocidas en humanos. Objetivo: Identificar los antecedentes patológicos familiares y las enfermedades durante el embarazo asociados a la aparición de defectos congénitos renales. Métodos: Estudio descriptivo prospectivo transversal realizado en 672 niños nacidos entre julio de 2014 y junio de 2015 en Santa Clara, con ultrasonido prenatal normal. A todos los niños durante la consulta médica se les hizo examen físico detallado y previo consentimiento informado del familiar acompañante, se aplicó a estos una encuesta y se registraron variables epidemiológicas, antecedentes familiares de enfermedades renales, morbilidad de la madre durante el embarazo y se realizó un ultrasonido renal para identificar las alteraciones sonográficas sugerentes de algún tipo de anomalías del desarrollo renal. Resultados: En 40 (5,95 por ciento) pacientes se detectó alteración sonográfica. El 27,50 por ciento eran hijos de madres que presentaron alguna enfermedad durante el embarazo. La glucemia elevada afectó 10 por ciento de las madres de los niños con anomalías del desarrollo renal, seguida del bajo peso materno (7,5 por ciento). El hecho de presentar antecedente patológico familiar de enfermedad renal aportó un riesgo de 1,88 y en las de tipo obstructivo el riesgo fue de 5,08. Conclusiones: Las alteraciones sonográficas sugestivas de malformación congénita renal son más frecuentes en los lactantes cuyas madres presentaron concentraciones elevadas de glucosa y bajo peso durante el embarazo. Los niños con antecedentes familiares de malformación renal tienen mayor riesgo de presentar una anomalía del desarrollo renal(AU)


Introduction: Kidney and urinary tract´s malformations represent among 20 and 30 percent of all malformations known in humans. Objective: To identify during pregnancy family pathological history and diseases associated to the onset of renal congenital malformations. Methods: Prospective, descriptive, cross-sectional study carried out to 672 children with normal prenatal ultrasound whom were born from July, 2014 to June 2015 in Santa Clara province. All children during the medical consultation had a detailed physical examination and previous informed concent; it was applied also a survey and the epidemiologic variables, family history of renal diseases, morbility of the mother during pregnancy were recorded, and it was made a renal ultrasound to identify sonographic alterations suggesting any kind of anomaly in the renal development. Results: In 40 patients (5,95 percent), it was detected any sonographic alteration. 27,50 percent were children of mothers that presented any disease during pregnancy. High glycemia affected the 10 percent of mothers of children with anomalies in the renal development, followed by low maternal weight (7,5 percent). The fact of presenting a family pathological history of renal disease implied a risk of 1,88 percent and the risk was of 5,08 percent in the obstructive kind of diseases. Conlusions: Sonographic alterations suggesting renal congenital malformations are more frequent in newborns whose mothers had high concentrations of glycemia and low weight during pregnancy. Children with family history of renal malformations have higher risk of presenting an anomaly of the renal development(AU)


Subject(s)
Humans , Male , Female , Infant , Congenital Abnormalities/diagnosis , Renal Insufficiency, Chronic/etiology , Kidney/abnormalities , Urinary Tract/abnormalities , Epidemiology, Descriptive , Cross-Sectional Studies , Prospective Studies
17.
Rev. cuba. pediatr ; 92(2): e1070, abr.-jun. 2020. tab, graf
Article in Spanish | LILACS, CUMED | ID: biblio-1126750

ABSTRACT

Introducción: El ultrasonido prenatal aporta una magnífica forma de introducirnos en la patofisiología renal humana, pero es incapaz de detectar todas las anomalías. Objetivos: Identificar las principales anomalías de riñón y tracto urinario en pacientes con diagnóstico prenatal o posnatal de estas anomalías. Métodos: Se incluyeron en el estudio todos los pacientes que llegaron remitidos al servicio de Nefrología del Hospital Pediátrico Docente William Soler entre el 1ero. de octubre de 2015 y el 30 de septiembre de 2017, por haberse detectado alteraciones en el ultrasonido prenatal durante el seguimiento de un embarazo normal y aquellos en los que después del nacimiento se comprobó alguna anormalidad en forma incidental o por síntomas relacionados. Se programó seguimiento clínico, imagenológico y terapéutico de acuerdo con la anomalía detectada. Resultados: El estudio incluyó 81 pacientes, 65 con diagnóstico prenatal y 16 con hallazgo posnatal. El sexo masculino estuvo representado por el 66,7 por ciento y la anomalía más frecuente estudiada resultó la displasia renal multiquística (23,4 por ciento). En segundo lugar, el diagnóstico morfológico correspondió a dilataciones del tracto urinario, que en su estudio posnatal se clasificaron como hidronefrosis (20,9 por ciento), pielectasias (17,4 por ciento) y reflujo vesicoureteral (7,4 por ciento). Conclusiones: El ultrasonido prenatal para la detección de anomalías de riñón y tracto urinario es un proceder diagnóstico de gran utilidad porque permite prepararnos para enfrentar estas anomalías antes que presente síntomas relacionados y además puede proporcionar una adecuada información a los padres. No todas las anomalías congénitas se detectan mediante ecografía prenatal(AU)


Introduction: The prenatal ultrasound provides a great way to introduce us to the human renal pathophysiology, but is unable to detect all of the anomalies. Objectives: To identify the main anomalies of the kidney and urinary tract in patients with prenatal or postnatal diagnosis of those. Methods: There were included in the study all the patients who were referred to the Nephrology Service of William Soler Pediatric Teaching Hospital from October 1, 2015 to September 30, 2017 being detected alterations in the prenatal ultrasound during the follow-up of a normal pregnancy and those in which after birth any abnormality was found incidentally or by related symptoms. Clinical, imaging and therapeutic follow-up were scheduled in accordance with the anomaly detected. Results: The study included 81 patients, 65 with prenatal diagnosis and 16 with post-natal finding. The male sex was represented by the 66.7 percent and the most common anomaly studied was the multicystic dysplastic kidney (23.4 percent). Secondly, the morphological diagnosis corresponded to dilations of the urinary tract, which in the post-natal study were classified as hydronephrosis (20.9 percent), pyelectasis (17.4 percent) and vesicoureteral reflux (7.4 percent). Conclusions: The prenatal ultrasound for the detection of kidney and urinary tract´s anomalies is a diagnosis of great utility because it allows us to prepare to face these anomalies before they present related symptoms and it can also provide adequate information to parents. Not all congenital anomalies are detected by prenatal ultrasound(AU)


Subject(s)
Humans , Male , Female , Pregnancy , Infant, Newborn , Urinary Tract/abnormalities , Urinary Tract/diagnostic imaging , Kidney/abnormalities , Kidney/diagnostic imaging , Postnatal Care/methods , Epidemiology, Descriptive , Cross-Sectional Studies , Prospective Studies , Ultrasonography, Prenatal/methods
18.
Rev. colomb. nefrol. (En línea) ; 7(1): 70-83, ene.-jun. 2020. tab
Article in Spanish | LILACS, COLNAL | ID: biblio-1144375

ABSTRACT

Resumen Las infecciones en personas con enfermedad renal crónica son una causa importante de morbimortalidad. Los pacientes renales presentan factores de riesgo específicos para la adquisición de infecciones, que además suelen ser más graves, de progresión más rápida y de resolución más lenta que en sujetos sanos. La infección del tracto urinario en esta población es a menudo complicada debido a la presencia de diabetes, microorganismos multirresistentes, anomalías anatómicas o funcionales del tracto urinario, alteraciones metabólicas y el uso frecuente de sonda vesical. Las infecciones urinarias ocasionan una de las tasas más altas de hospitalización en diálisis y son muy prevalentes en el trasplante renal. Este trabajo tiene como objetivo revisar la literatura publicada sobre la etiología, el diagnóstico microbiológico y el tratamiento de las infecciones del tracto urinario en pacientes con enfermedad renal crónica.


Abstract Infections in chronic kidney disease patients are a major cause of morbidity and mortality. Renal patients have specific risk factors for acquiring infections, which also tend to be more severe and have a more rapid progression and slower resolution than in the healthy individuals. Urinary tract infection in renal patients is often complicated due to the presence of diabetes, multiresistant microorganisms, anatomic or functional abnormalities of the urinary tract, metabolic disturbances and the frequent use of urinary catheters. It causes one of the highest rates of hospitalization among dialysis patients and is highly prevalent in kidney transplantation. The aim of this work is to review the etiology, microbiological diagnosis and treatment of urinary tract infections in chronic kidney disease patients.


Subject(s)
Humans , Male , Female , Urinary Tract Infections , Renal Insufficiency, Chronic , Spain , Urinary Tract , Morbidity , Renal Replacement Therapy , Urinary Catheters , Literature
19.
Int. j. morphol ; 38(2): 292-298, abr. 2020. tab, graf
Article in English | LILACS | ID: biblio-1056437

ABSTRACT

Trans-obturator tape (TOT) and tension free vaginal tape (TVT) procedures are efficient treatment options, which reduce the surgical complications and provide adequate support to urethra in case of increased abdominal pressure to prevent stress urinary incontinence (SUI). The aim of this study is to evaluate the effect and efficacy of 3D printed female anatomical model on the training of TOT and TVT procedures. A 3D printed female anatomical model was produced for MedTRain3DModSim, Erasmus+ European Union project led by Turkey with the participation of Greece, Italy, Czech Republic and South Korea. Face and content validities of the model evaluated by the participants and the experts respectively. During two learning & teaching & training activities and a multiplier event of the project between 2016 and 2018; 41 medical students, 30 residents and 19 specialists of urology and gynecology were educated and performed TOT and TVT procedures with this model under the mentorship of 3 experts. All participants were assessed and scored for their achievement on both procedures with model according to 7 parameters by the experts. There was no statistical difference between the students and residents for each parameter. All the parameters of the students and specialists were statistically different. 3D anatomical models produced from real data and mimicking different types of tissues are suitable for basic anatomy education of students and residents, hands on training for junior surgeons before cadaveric courses in hybrid education system, surgical planning of the surgeons and informing the patients before the operation.


Los procedimientos de cinta transobturadora (TOT) y cinta vaginal sin tensión (TVT) son opciones de tratamiento eficientes, que reducen las complicaciones quirúrgicas y proporcionan un soporte adecuado a la uretra en caso de aumento de la presión abdominal para prevenir la incontinencia urinaria de esfuerzo (IUE). El objetivo de este estudio fue evaluar el efecto y la eficacia del modelo anatómico femenino impreso en 3D en el entrenamiento de los procedimientos TOT y TVT. Se produjo un modelo anatómico femenino impreso en 3D para MedTRain3DModSim, proyecto Erasmus + de la Unión Europea dirigido por Turquía con la participación de Grecia, Italia, la República Checa y Corea del Sur. Validez facial y de contenido del modelo fueron evaluados por los participantes y los expertos respectivamente. Durante dos actividades de aprendizaje, enseñanza y capacitación y un evento multiplicador del proyecto entre 2016 y 2018; 41 estudiantes de medicina, 30 residentes y 19 especialistas en urología y ginecología fueron capacitados y realizaron procedimientos TOT y TVT de este modelo bajo la tutoría de 3 expertos. Todos los participantes fueron evaluados y calificados por los expertos, por su logro en ambos procedimientos con el modelo de acuerdo con 7 parámetros. No hubo diferencia estadística entre los estudiantes y los residentes para cada parámetro. Todos los parámetros de los estudiantes y especialistas fueron estadísticamente diferentes. Los modelos anatómicos en 3D producidos a partir de datos reales e imitando diferentes tipos de tejidos son adecuados para la educación básica de anatomía de estudiantes y residentes. Además de ofrecer una capacitación práctica para los cirujanos antes de los cursos cadavéricos en el sistema educativo, y una planificación quirúrgica de los cirujanos e información para los pacientes antes de la cirugía.


Subject(s)
Humans , Female , Urinary Incontinence, Stress , Urinary Tract/anatomy & histology , Suburethral Slings , Models, Anatomic , Printing, Three-Dimensional
20.
Infectio ; 24(1): 9-14, ene.-mar. 2020. tab, graf
Article in English | LILACS, COLNAL | ID: biblio-1090537

ABSTRACT

Abstract Objective: To evaluate the cost-effectiveness of ceftolozane/tazobactam + metronidazole (C/T+M) and ceftolozane/tazobactam (C/T) compared with 8 alternatives used in the treatment of complicated intraabdominal infection (cIAI) and complicated urinary tract infection (cUTI) respectively. Methods: A Monte Carlo simulation decision model was used for the estimation and comparison of treatment-related costs, and quality adjusted life years for patients with cIAI treated with C/T+M in comparison with cefepime + metronidazole, ciprofloxacin + metronidazole, doripenem, levofloxacin + metronidazole, meropenem, piperacillin/tazobactam, ceftazidime + metronidazole or imipenem/cilastatin and patients with cUTI treated with C/T in comparison with cefepime, ciprofloxacin, doripenem, levofloxacin, meropenem, piperacillin/tazobactam, ceftazidime or imipenem/cilastatin. Local costs were estimated using base cases identified by experts and consulting local databases. Sensitivity values of the PACTS (Program to Assess Ceftolozane/Tazobactam Susceptibility) study in Latin America were used in the model. Results: C/T+M and C/T obtained incremental cost-effectiveness ratios (ICER) that were below the Colombian cost-effectiveness threshold (3 GDP per capita) in most comparisons, and were dominated by meropenem, considering only gram-negative microorganisms. Sensitivity assessments were also carried out, in which only the population with P. aeruginosa infections was considered, showing positive results for C/T+M and C/T (cost-effective or dominant with regards to all comparators). Conclusions: C/T+M and C/T could be cost-effective alternatives in the treatment of CIAI and CUTI in Colombia, when there is an adequate and rational use of antibiotics. The results of the sensitivity analyses showed dominance and cost-effectiveness with regards to every comparator in patients infected with P. aeruginosa


Resumen Objetivo: Evaluar la costo-efectividad de ceftolozano/tazobactam + metronidazol (C/T + M) y ceftolozano/tazobactam (C/T) en comparación con 8 alternativas utilizadas en el tratamiento de las infecciones intraabdominales complicadas (IAAc) e infecciones del tracto urinario complicadas (ITUc) respectivamente. Métodos: Se usó un modelo de decisión de simulación de Monte Carlo para la estimación y comparación de los costos relacionados con el tratamiento y los años de vida ajustados por calidad para pacientes con IAAc tratados con C/T + M, en comparación con cefepima + metronidazol, ciprofloxacina + metronidazol, doripenem , levofloxacina + metronidazol, meropenem, piperacilina / tazobactam, ceftazidima + metronidazol o imipenem/cilastatina, y pacientes con ITUc tratados con C/T en comparación con cefepime, ciprofloxacina, doripenem, levofloxacina, meropenem, piperacilina / tazobactam, ceftazidima o imipenem/cilastatina . Los costos locales se estimaron por medio de casos base identificados por expertos y consultando bases de datos locales. Se utilizaron los valores de sensibilidad bacteriana del estudio PACTS (Programa para evaluar la susceptibilidad al ceftolozano/tazobactam) en América Latina para poblar el modelo. Resultados: C/T + M y C/T obtuvieron razones de costo-efectividad incrementales (RCEI) que estaban por debajo del umbral de costo-efectividad colombiano (3 PIB per cápita) en la mayoría de las comparaciones, y fueron dominados por meropenem, considerando solo microorganismos gran-negativos También se llevaron a cabo análisis de sensibilidad, en los que solo se consideró la población con infecciones por P. aeruginosa, mostrando resultados positivos para C/T + M y C/T (costo efectivo o dominante con respecto a todos los comparadores). Conclusiones: C/T + M y C/T podrían ser alternativas costo efectivas en el tratamiento de IAAc e ITUc en Colombia, cuando existe un uso adecuado y racional de antibióticos. Los resultados de los análisis de sensibilidad mostraron dominio y costo-efectividad en relación con todos los comparadores en pacientes infectados con P. aeruginosa.


Subject(s)
Humans , Female , Urinary Tract , Intraabdominal Infections , Tazobactam , Cost-Benefit Analysis , Colombia , Sepsis , Metronidazole/pharmacology , Anti-Bacterial Agents/pharmacology
SELECTION OF CITATIONS
SEARCH DETAIL