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1.
Rev. Pesqui. (Univ. Fed. Estado Rio J., Online) ; 12: 440-446, jan.-dez. 2020. tab
Article in English, Portuguese | LILACS (Americas), BDENF | ID: biblio-1052977

ABSTRACT

Objetivo: analisar o rastreamento do câncer do colo do útero de um município do Sul do Brasil. Método: realizou-se um estudo quantitativo descritivo retrospectivo pela análise dos laudos dos exames citopatológicos registrados no Sistema de Informação do Câncer. Resultados: identificou-se que a maioria dos exames foram realizados em mulheres alvo do programa, apesar da baixa cobertura do rastreamento. O reduzido número de amostras insatisfatórias representa um aspecto positivo. Em contrapartida, um número considerável das amostras não obteve representatividade da junção escamo-colunar, este constitui um ponto crítico a ser melhorado na eficácia do exame, uma vez que, verificou-se associação significativa entre a representação dos epitélios e alterações anormais. Conclusão: os achados deste estudo reforçam a importância da avaliação e do monitoramento constante da qualidade dos exames coletados, para que sejam efetivos no rastreamento das lesões que são precursoras do câncer do colo do útero


Objective: to analyze the cervical cancer screening of a municipality in the South of Brazil. Method: A retrospective descriptive quantitative study was performed by analyzing the reports of the cytopathological exams registered in the Cancer Information System. Results: It was identified that the majority of the exams were performed in women targeted by the program, despite the low coverage of the screening. The small number of unsatisfactory samples represents a positive aspect. In contrast, a considerable number of samples obtained not representative of the squamocolumnar junction, this is a critical point to be improved in the efficiency of the examination, since it was found a significant association between the representation and the abnormal changes epithelia. Conclusion: the findings of this study reinforce the importance of the evaluation and constant monitoring of the quality of the exams collected, so that they are effective in tracking the lesions that are precursors of cervical cancer


Objetivo: analizar el rastreo del cáncer del cuello del útero de un municipio del sur de Brasil. Método: se realizó un estudio cuantitativo descriptivo retrospectivo por el análisis de los laudos de los exámenes citopatológicos registrados en el Sistema de Información del Cáncer. Resultados: se identificó que la mayoría de los exámenes se realizaron en las mujeres objetivo del programa, a pesar de la baja cobertura del rastreo. El reducido número de muestras insatisfactorias es un aspecto positivo. En cambio, un número considerable de muestras no obtuvo representatividad de la unión escamoso-colunar, éste constituye un punto crítico que debe mejorarse en la eficacia del examen, ya que se ha observado una asociación significativa entre la representación de los epitelios y las alteraciones anormales. Conclusión: los hallazgos de este estudio refuerzan la importancia de la evaluación y del monitoreo constante de la calidad de los exámenes recogidos, para que sean efectivos en el rastreo de las lesiones que son precursoras del cáncer del cuello del útero


Subject(s)
Humans , Female , Adult , Middle Aged , Aged , Uterine Cervical Neoplasms/nursing , Uterine Cervical Neoplasms/prevention & control , Uterine Cervical Neoplasms/epidemiology , Papanicolaou Test/statistics & numerical data , Women's Health Services , Retrospective Studies , Family Health Strategy
2.
Rev. Bras. Saúde Mater. Infant. (Online) ; 19(3): 641-649, Jul.-Sept. 2019. tab
Article in English | LILACS (Americas) | ID: biblio-1041084

ABSTRACT

Abstract Objectives: to determine the incidence of the main high oncogenic risk types of the human papillomavirus (HPV) ( 16, 18, 31 and 33) and the risk factors for cervical adenocarcinoma. Methods: a case-control study was carried out with 324 women (69 with adenocarcinoma and 260 healthy controls) between 2001 and 2014. Information on risk factors associated with adenocarcinomawere collected and the detection performed on HPVby using Polymerase Chain Reaction (PCR) method. Results: adenocarcinoma was associated with age ≥40 years old (OR=2.95; 95%CI=1.13-7.71), ≤3 years of schooling (OR=2.34; 95%CI=1.02-5.37), presence of HPV (OR=6.75; 95%CI=2.41-18.91),women in menopausal status (OR=4.76; 95%CI:1.70-13.31) black race (OR=6.71; 95%CI= 2.11-21.32) and never had undergone cervical cancer screening (OR=9.92; 95%CI:2.41-40.81). Andamong the HPV types detected, HPV 18 was observed to be strongly associated with adenocarcinoma of the cervix (OR=99.1; 95%CI=12.96-757.78). Conclusions: the factors associated with cervical adenocarcinoma were ≥40 years old, ≤3 years of schooling, black race, menopausal status, never had undergone cervical cancer screening and the presence of HPV.


Resumo Objetivos: determinar a incidência dos principais Papilomavirus Humano (HPV) de alto risco oncogênico (16, 18, 31 e 33) e os fatores associados ao adenocarcinoma do colo uterino. Métodos: realizado estudo de caso-controle com 324 mulheres (69 com adenocarcinoma e 260 controles saudáveis), de 2001 a 2014. Foram colhidas informações sobre fatores de risco associados ao adenocarcinoma e realizada a detecção do HPV pelo método da Reação em Cadeia da Polimerase (PCR). Resultados: o adenocarcinoma foi associado à idade >40 anos (OR=2,95; IC95%=1,13 - 7,71), escolaridade <3 anos (OR=2,34; IC95%=1,02 - 5,37), presença do HPV (OR=6,75; IC95%=2,41 - 18,91), mulher no estado menopausal (OR=4,76; IC 95%=1,70 - 13,31), raça negra (OR=6,71; IC95%=2,11 - 21,32) e nunca ter feito o exame de prevenção de Papanicolau (OR=9,92; IC95%=2,41 - 40,81). Entre os tipos de HPV encontrados observou-se que HPV 18 teve forte associação (OR=99,1; IC95%=12,96 - 757,78) com o adenocarcinoma de colo uterino. Conclusões: os fatores associados ao adenocarcinoma de colo uterino foram idade >40 anos, escolaridade <3 anos, raça negra, estado menopausal, nunca ter realizado o Papanicolau e presença do HPV.


Subject(s)
Humans , Female , Adult , Papillomaviridae/genetics , Adenocarcinoma/epidemiology , Uterine Cervical Neoplasms/epidemiology , Papillomaviridae/classification , Brazil , Case-Control Studies , Polymerase Chain Reaction , Incidence , Risk Factors
3.
Rev. medica electron ; 41(4): 914-927, jul.-ago. 2019. tab
Article in Spanish | LILACS (Americas), CUMED | ID: biblio-1094098

ABSTRACT

RESUMEN Introducción: entre las enfermedades crónicas no transmisibles se encuentra el cáncer cérvico uterino, el cual constituye una de las principales causas de muerte en la actualidad. En los últimos años la morbilidad de este tipo de cáncer ha influido notablemente en los indicadores de salud y la calidad de vida de la población femenina mundial. Objetivo: diseñar una intervención educativa para la prevención del cáncer cérvico uterino, en estudiantes de primer año de la carrera de Medicina en la Universidad de Ciencias Médicas de Matanzas. Materiales y métodos: investigación de Desarrollo la cual requiere un estudio observacional, descriptivo, que se inserta en el Programa Ramal Enfermedades Crónicas no Transmisibles. El universo de estudio 740 adolescentes la muestra 246 alumnos, seleccionada mediante un muestreo sistemático. Resultados: la mayoría de los estudiantes reflejan como estado civil solteros o bajo unión consensual, el comienzo de las relaciones sexuales tiene mayor incidencia en las edades de 14 a 15 años aunque es significativa la cifra de adolescentes que entre los 16 y 17 años que inician las relaciones sexuales. En cuanto a la presencia de los factores de riesgo del cáncer cérvico uterino como múltiples compañeros sexuales, uso de tabletas anticonceptivas, presencia del hábito de fumar así como infecciones de transmisión sexual se evidenciaron con cifras más significativas múltiples compañeros sexuales y el uso de tabletas anticonceptivas, en cuanto a la distribución de motivos que impulsaron al inicio de las relaciones sexuales, se destacan los motivos de experimentar sensaciones nuevas, el hecho de complacer a la pareja y la presión grupal respectivamente, solo 5.28% responde a una búsqueda de placer. Conclusiones: los estudiantes presentan factores de riesgo de considerable magnitud de padecer cáncer cérvico uterino. Se diseñó la propuesta de intervención educativa.


ABSTRACT Introduction: cervical cancer is one of the non-communicable chronic diseases. It is currently one of the main causes of death. During the last years, this kind of cancer morbidity has notably struck on health and life quality indicators of female population around the world. Objective: to design an educative intervention for preventing cervical cancer in students of the first year of Medicine studies in the University of Medical Sciences of Matanzas. Materials and methods: development research demanding a descriptive, observational study, inserted in the Branch Program Non-communicable Chronic Diseases. The universe of study is 740 teenagers, and the sample, systematically sampled, 246 students. Results: most of students gave the category of single or consensual union as marital status; the beginning of sexual relationships has higher incidence at the age of 14-15 years, although it is significant the quantity of adolescents beginning sexual relationships at the ages of 16 and 17 years. In order to the presence of cervical cancer risk factors like multiple sexual partners, contraceptive tablets use, smoking habit and sexually transmitted infections (STI), multiple sexual partners and the use of contraceptive tablets showed the most significant quantities; and about the distribution of the motives boosting the beginning of sexual relationships are highlighted the motives of experimenting new sensations, the fact of pleasing the sexual partner and the group pressure, respectively; just 5.28 % answered it was looking for pleasure. Conclusions: students have considerable risk factors of suffering cervical cancer. A proposal of educative intervention was designed.


Subject(s)
Humans , Female , Adolescent , Sex Education , Uterine Cervical Neoplasms/diagnosis , Uterine Cervical Neoplasms/mortality , Uterine Cervical Neoplasms/prevention & control , Uterine Cervical Neoplasms/epidemiology , Health Knowledge, Attitudes, Practice , Risk Factors , Students, Public Health , Early Medical Intervention , Preventive Health Services , Research , Smoking , Sexually Transmitted Diseases , Epidemiology, Descriptive , Contraceptives, Oral/therapeutic use , Unsafe Sex , Education , Observational Study , Healthy Lifestyle
4.
Mem. Inst. Invest. Cienc. Salud (Impr.) ; 17(1): 6-15, abr. 2019. ilus, tab
Article in Spanish | LILACS (Americas), BDNPAR | ID: biblio-1007859

ABSTRACT

En Paraguay la incidencia de cáncer de cuello uterino (CCU) es superior a las observadas en otros países de la región. El agente etiológico asociado al CCU es el virus papiloma humano (VPH), esencialmente tipos de alto riesgo oncogénicos. El objetivo es describir aspectos epidemiológicos de la infección genital por el virus papiloma humano de alto riesgo (VPH-AR) en mujeres de 25 a 64 años que consultaron en servicios de Patología Cervical del MSPyBS, de mayo a diciembre de 2013. Se utilizó el Cobas 4800 HPV Test (Roche) que permite la detección individual de VPH-16 y VPH-18 y un pool de otros VPH-AR que incluye 12 genotipos de alto riesgo. Los otros VPH-AR fueron tipificados por hibridación reversa en línea (RLB). Entre las 495 mujeres incluidas, se detectaron 72 casos positivos (14,5%) de VPH-AR. Se identificaron 19 tipos virales; siendo el más frecuente VPH-16 (2,1%), seguido del VPH-31, 33, 58 y 66; el VPH-18 aparece en sexto lugar. Este trabajo aporta los primeros datos sobre la implementación de técnicas moleculares para detección y tipificación de VPH como parte del sistema de salud pública de Paraguay. El predominio de VPH-16, confirma su amplia circulación a nivel mundial y dado su mayor potencial oncogénico, representa una alerta a considerar, en especial en las mujeres mayores de 30 años portadoras de una infección persistente. Estos resultados apoyan la importancia de la implementación criteriosa y la utilización apropiada de las pruebas moleculares actualmente disponibles para la prevención y control del CCU(AU)


Subject(s)
Humans , Female , Adult , Middle Aged , Papillomaviridae/genetics , Uterine Cervical Neoplasms/epidemiology , Uterine Cervical Neoplasms/virology , Papillomavirus Infections/epidemiology , Papillomavirus Infections/virology , Paraguay/epidemiology , Cross-Sectional Studies , Human papillomavirus 16/genetics , Human papillomavirus 18/genetics , Genotyping Techniques
5.
Rev. salud pública ; 21(2): 161-167, ene.-abr. 2019. tab, graf
Article in English | LILACS (Americas), Inca | ID: biblio-1101852

ABSTRACT

ABSTRACT Objective To describe cervical cancer mortality rates and their corresponding trends, and to analyze the spatial correlations of this type of cancer in Natal-RN, Brazil, between 2000 and 2012. Materials and Methods The simple linear regression model, the empirical Bayes method and the Global Moran's index were used for the statistical analysis. Results The mortality coefficient of cervical cancer in Natal, standardized by age range, was 5.5 per 100 000 women. All historical series for the coefficients studied were classified as stable. The Global Moran's index obtained was 0.048, with a p-value for the spatial test correlation between neighborhoods of 0.300. The average family income by neighborhood showed no significant correlation to cervical cancer mortality rates. Conclusion This study found a temporal stabilization and spatial independence trend of cervical cancer mortality rates in women from Natal, as well as the absence of correlation between these rates and the average family income of the of the participating women distributed by neighborhoods. In view of this, changes in the public policies should be made aimed at preventing the disease; adopting these measures could positively impact the screening program, improving the coverage of Pap smears and immunization campaigns against HPV, in order to reverse this trend and achieve a reduction of mortality rates.(AU)


RESUMEN Objetivo Describir las tasas de mortalidad por cáncer de cuello uterino y sus tendencias, así como analizar las correlaciones espaciales de este tipo de cáncer en Natal-RN, Brasil, entre 2000 y 2012. Materiales y Métodos Para el análisis estadístico se utilizaron el modelo de regresión lineal simple, la estimación empírica de Bayes y el índice Moran Global. Resultados La tasa de mortalidad por cáncer de cuello uterino en Natal, estandarizado por rango de edad, fue 5.5 por cada 100 000 mujeres. Todas las series históricas para los coeficientes estudiados se clasificaron como estables. El índice Moran Global obtenido fue 0.048, con un valor p de 0.300 para la correlación de prueba espacial entre vecindarios. El ingreso familiar promedio por vecindario no mostró correlación significativa con las tasas de mortalidad por cáncer de cuello uterino. Conclusión En este estudio se observó una tendencia temporal de estabilización e independencia espacial de la tasa de mortalidad por cáncer cervical en mujeres de Natal, así como la ausencia de correlación entre estas tasas y el ingreso familiar promedio de las mujeres participantes, distribuidas por vecindarios de la ciudad. En vista de esto, se sugiere que se adopten cambios en las políticas públicas dirigidas a la prevención de la enfermedad que apunten a medidas que puedan tener un impacto positivo en el programa de monitoreo, mejorando la cobertura de la prueba de Papanicolaou, así como de las campañas de vacunación contra el VPH, con el objetivo de revertir esta tendencia y lograr una reducción en las tasas de mortalidad de la enfermedad.(AU)


Subject(s)
Humans , Female , Uterine Cervical Neoplasms/mortality , Uterine Cervical Neoplasms/prevention & control , Uterine Cervical Neoplasms/epidemiology , Immunization Programs/supply & distribution , Papanicolaou Test/instrumentation , Statistical Analysis , Bayes Theorem , Spatio-Temporal Analysis
6.
Femina ; 47(1): 55-60, 20190131. ilus
Article in Portuguese | LILACS (Americas) | ID: biblio-1046493

ABSTRACT

O câncer do colo do útero é o câncer mais comum na gravidez, com uma estimativa de 1 a 12 casos por 10.000 gestações. Com a melhora do rastreio do câncer do colo do útero e uma tendência feminina de engravidar em idade mais avançada, observa-se que cerca de 43% das pacientes diagnosticadas com câncer do colo do útero têm menos de 45 anos e 20% a 28% são menores de 40 anos. O diagnóstico e o tratamento da doença na gravidez são difíceis e desafiadores, pois geram angústia para a gestante, sua família e os profissionais de saúde. Novos estudos destacam que a preservação da fertilidade e a qualidade de vida estão se tornando preocupações cada vez mais importantes de mulheres jovens com câncer e que os procedimentos cirúrgicos devem ser menos invasivos. O comitê de oncologia da FIGO revisou o sistema de estadiamento do câncer do colo do útero. Este artigo discute o diagnóstico e tratamento do câncer do colo do útero com base no estágio da doença, incluindo atenção a questões de fertilidade e qualidade de vida.(AU)


Cervical cancer is the most common cancer in pregnancy, with an estimated 1-12 cases per 10,000 pregnancies. With improved cervical cancer screening and a tendency to become pregnant at a later age, it is noted that about 43% of patients diagnosed with cervical cancer are younger than 45 and 20-28% are younger than 40 years. Diagnosis and treatment of the disease in pregnancy are difficult and challenging, as they create distress for pregnant women, their families and health professionals. New studies highlight that preserving fertility and quality of life are becoming increasingly important concerns for young women with cancer and that surgical procedures should be less invasive. The FIGO oncology committee reviewed the staging system for cervical cancer. This article discusses the diagnosis and treatment of cervical cancer based on the stage of the disease, including attention to issues of fertility and quality of life.(AU)


Subject(s)
Humans , Female , Pregnancy , Pregnancy Complications, Neoplastic/pathology , Uterine Cervical Neoplasms/surgery , Uterine Cervical Neoplasms/diagnosis , Uterine Cervical Neoplasms/radiotherapy , Uterine Cervical Neoplasms/diagnostic imaging , Prognosis , Uterine Cervical Neoplasms/mortality , Uterine Cervical Neoplasms/epidemiology , Pregnancy, High-Risk
7.
Revista Digital de Postgrado ; 8(3): e179, 2019. tab
Article in Spanish | LILACS (Americas), LIVECS | ID: biblio-1094822

ABSTRACT

Determinar la prevalencia de las lesiones intraepiteliales cervicales de bajo y alto grado en pacientes de edad fértil en la consulta de ginecología del centro Materno pediatrico Zulia, en el período comprendido febrero 2016 -febrero 2018 Maracaibo, Estado Zulia. Métodos: Se realizó un estudio descriptivo retrospectivo en el que se incluyeron mujeres entre los 15 y 44 años, que acudieron a la consulta de Ginecología obstetricia del centro materno pediátrico Zulia para el periodo comprendido febrero 2016 ­ febrero 2018. Se evaluó la normalidad de las variables cuantitativas, empleándose la mediana o el promedio con sus varianzas según su distribución, y frecuencias y proporciones para las variables categóricas. Resultados: Se incluyeron 150 pacientes. La mediana de la edad fue 29 años con rango (R: 15-43 años), la mediana del número de partos 1 (R: 0-3). Uso de métodos anticonceptivos, la mayoría utilizaba ACO. El 60% de las citologías se reportaron como negativas, 20 % lesión de bajo grado (LSIL), 10% células escamosas atípicas de significado indeterminado (ASC-US), 2% lesiones de alto grado (HSIL), 2,3% células escamosas atípicas de significado indeterminado de alto grado ASC-H, 3,3% células glandulares atípicas de significado incierto (ASGUS) y 2% carcinoma invasor. Conclusión: La prevalencia de las anormalidades citológicas fue alta en todos los grupos analizados, sin embargo, existe un mayor número de LSIL hacia la tercera década de la vida y en aquellas que iniciaron su vida sexual después de los 40 años. De igual manera se encontró una relación inversa entre el número de partos, planificación familiar hormonal y aparición de lesiones pre neoplásicas(AU)


To determine the prevalence of cervical intraepithelial lesions of low and high grade in patients of fertile age in the gynecology clinic of the Zulia maternity center, in the period February 2016-February 2018 Maracaibo, Zulia State. Methods: A retrospective descriptive study was carried out that included women between 15 and 44 years old, who attended the obstetrics gynecology clinic of the Zulia pediatric maternity center for the period February 2016-February 2018. The normality of the quantitative variables, using the median or average with their variances according to their distribution, and frequencies and proportions for the categorical variables. Results: 150 patients were included. the median age was 29 years with range (R: 15-43 years), the median number of births 1 (R: 0-3). Using contraceptive methods, most used ACO. 60% of cytologies were reportedas negative, 20% low grade lesion (LSIL), 10% atypical squamous cells of undetermined significance (ASC-US), 2% high grade lesions (HSIL), 2.3% cells Atypical squamous of indeterminate significance of high grade ASC-H, 3.3% atypical glandular cells of uncertain significance (ASGUS) and 2% invasive carcinoma. Conclusion: The prevalence of cytological abnormalities was high in all the groups analyzed, however, there is a greater number of LSIL in the third decade of life and in those who began their sexual life their 40 years. Likewise, an inverse relationship was found between the number of births, hormonal family planning and the appearance of pre-neoplastic lesions(AU)


Subject(s)
Humans , Female , Adolescent , Adult , Uterine Cervical Neoplasms/diagnosis , Uterine Cervical Neoplasms/pathology , Uterine Cervical Neoplasms/epidemiology , Cervical Intraepithelial Neoplasia/diagnosis , Papillomavirus Infections/diagnosis , Biopsy/instrumentation , Biopsy/statistics & numerical data , Retrospective Studies , Colposcopy/instrumentation , Papanicolaou Test/statistics & numerical data , Squamous Intraepithelial Lesions of the Cervix/pathology
8.
Rev. salud pública ; 20(6): 718-724, nov.-dic. 2018. tab
Article in Portuguese | LILACS (Americas) | ID: biblio-1020849

ABSTRACT

RESUMO Objetivo Caracterizar aspectos sociodemográficos e clínicos de idosas com câncer do colo do útero no Maranhão, Brasil. Método Estudo retrospectivo, descritivo de base secundária. Resultados 553 idosas com câncer do colo do útero no período de 2009 a 2013, cadastrados no registro de base hospitalar de câncer. Apresentavam média de idade 69,91 anos, com predomínio de mulheres de cor parda 46%, ensino fundamental incompleto com 42%, estado civil casadas 45,4%, e nunca terem tido hábitos etilista e tabagista com 58,3% e 39,4%. O carcinoma de células escamosas foi o mais frequente 80,5%, com estadiamento tardio 3B 29,0%. Ao final do primeiro tratamento, 43,6% encontravam-se sem evidência de doença ou em remissão completa. Conclusão Os resultados apontam necessidade de buscar melhorar as campanhas para a faixa etária estudada. Melhorando a cobertura por meio de campanhas de estímulo à realização do exame citopatológico, e estimulem os profissionais da área da saúde a identificar as mulheres em atraso na realização desse exame, quando do seu comparecimento aos serviços de saúde, evitando, assim, a perda de oportunidades de prevenção.(AU)


ABSTRACT Objective To characterize sociodemographic and clinical aspects of elderly women with cervical cancer in Maranhão, Brazil. Materials and Method Retrospective and descriptive study of secondary sources. Results 559 elderly women with cervical cancer from 2009 to 2013 and registered in the hospital-based cancer registry were included in the study. The mean age was 69.91 years, with a predominance of brown women (46%), with incomplete primary education (42%), married (45.4%), and without drinking and smoking habits (58.3% and 39.4%, respectively). Squamous cell carcinoma was the most frequent type pf cancer (80.5%) with advanced stage 3B in 29.0% of the cases. At the end of the first treatment, 43.6% did not show any evidence of disease or complete remission. Conclusion Results point to the need to improve campaigns for the age group studied, as well as the coverage through campaigns to promote cytopathological examination. Also health professionals should be encouraged to identify women who are behind in the examination when attending health services, thus avoiding the loss of prevention opportunities.(AU)


RESUMEN Objetivo Caracterizar aspectos sociodemográficos y clínicos de ancianos con cáncer de cuello de útero en Maranhão, Brasil. Método Estudio retrospectivo, descriptivo de fuente secundaria. Resultados Se incluyeron 559 ancianos con cáncer del cuello del útero en el período de 2009 a 2013, del registro de base hospitalaria de cáncer. En el caso de las mujeres, eran de color pardo 46%, con educación básica incompleta 42%, casadas el 45,4%. El carcinoma de células escamosas fue el más frecuente (80,5%) con estadío tardío 3B el 29,0%, Al final del primer tratamiento, el 43,6% se encontraba sin evidencia de enfermedad o en remisión completa. Conclusión Los resultados apuntan a la necesidad de mejorar las campañas para el grupo de edad estudiado y la cobertura por medio de campañas de estímulo a la realización del examen citopatológico, así mismo, estimular a los profesionales del área de la salud a identificar a las mujeres atrasadas en la realización de ese examen durante su comparecencia a los servicios de salud, evitando así la pérdida de oportunidades de prevención.(AU)


Subject(s)
Humans , Female , Aged , Aging , Uterine Cervical Neoplasms/epidemiology , Women's Health , Brazil/epidemiology , Hospital Records/statistics & numerical data , Epidemiology, Descriptive , Retrospective Studies
9.
Rev. cuba. enferm ; 34(3): e1480, jul.-set. 2018. tab
Article in Spanish | LILACS (Americas), CUMED | ID: biblio-1099053

ABSTRACT

RESUMEN Introducción: El diagnóstico precoz del cáncer cérvicouterino es de importante práctica para mantener la salud. Objetivo: Identificar los factores de riesgo de lesiones precursoras del cuello de útero. Métodos: Estudio observacional de casos y controles en el Policlínico "Manuel Piti Fajardo" durante 2015. El universo estuvo constituido por 46 mujeres entre 25 y 59 años con citologías alteradas (grupo estudio) y, por muestreo aleatorio simple, se seleccionaron 46 mujeres de similar edad a las del estudio con citología negativa para el grupo control. La información se obtuvo aplicando una encuesta y de las tarjetas de citología orgánica, se utilizó el análisis porcentual, la media aritmética y la prueba de Chi-cuadrado para determinar asociaciones entre variables. Resultados: En el grupo estudio predominó el hábito de fumar (73,91 por ciento con X²= 35,28); el 60,87 por ciento con relaciones sexuales antes de los 15 años (X²=26,67); el condón fue utilizado por el 8,70 por ciento de las enfermas; el 36,96 % tuvo más de cuatro parejas sexuales y el 34,78 por ciento presentó papiloma humano (X²=134,08). Conclusiones: Se identificaron como factores de riesgo de lesiones precursoras del cuello de útero, el hábito de fumar, el inicio precoz de relaciones sexuales, no utilizar condón, tener varios compañeros sexuales y tener antecedentes de infecciones de transmisión sexual(AU)


ABSTRACT Introduction: Early diagnosis of uterine cervical cancer is an important practice to maintain health. Objective: To identify risk factors for precursor lesions of the cervix. Methods: An observational study of cases and controls in the Policlinico "Manuel Piti Fajardo" during 2015. The universe, consisting of 46 women between 25 and 59 years old with altered cytologies (study group), for the control group, by simple random sampling Selected 46 women of similar age to the negative cytology study. The information was obtained by applying a survey and the organic cytology cards, the percentage analysis, the arithmetic mean and the Chi-square test were used to determine associations between variables. Results: Smoking was predominant in the Study Group (73.91 percent with X² = 35.28); 60.87 percent with sexual intercourse before 15 years and (X² = 26.67); the condom was used by the 8.70 percent of the patients; 36.96 percent had more than four sexual partners and 34.78 % had human papilloma (X² = 134.08). Conclusions: Smoking factors, early onset of sexual intercourse, no condom use, multiple sexual partners, and a history of sexually transmitted infections were identified as risk factors for precursor cervical lesions(AU)


Subject(s)
Humans , Female , Adult , Carcinoma in Situ/diagnosis , Uterine Cervical Neoplasms/prevention & control , Uterine Cervical Neoplasms/epidemiology , Risk Factors , Case-Control Studies , Observational Studies as Topic
10.
Rev. salud pública Parag ; 8(2): [P15-P20], Jul - Dic 2018.
Article in Spanish | LILACS (Americas) | ID: biblio-980457

ABSTRACT

Introducción: El cáncer de cuello uterino es una de las patologías más graves en la vida de las mujeres. Causó 266 000 muertes en mujeres por esta patología en el año 2012, un 85% en los países de ingresos bajos y medianos. Objetivo: Determinar la prevalencia de lesiones precursoras de cáncer de cuello uterino y antecedentes sexuales/reproductivos de indígenas de Caaguazú durante los años 2015 a 2017. Materiales y métodos: Se realizó un estudio observacional, descriptivo, de corte transversal con muestreo no probabilístico. Se estudió a indígenas que se encuentran registrados en el Programa de Patología Cervical. Los datos obtenidos se ingresaron en Microsoft Excel© 2016, para el análisis se utilizó STATA® 14.0. Los resultados fueron presentados en tablas y gráficos. Resultados: Ingresaron en el estudio 129 indígenas con una edad media de 26±10 años. La prevalencia de lesiones precursoras de cáncer de cuello uterino fue de 13,18%. Las lesiones más frecuentemente encontradas en orden de frecuencia fueron ASCUS 10,08%; CIN I 2,32%; CIN II 0,77%; no se observó CIN III, ni carcinoma in situ. Las edades en las que se presentaron con mayor frecuencia fueron entre 25 a 44 años en un 70,59%. El 58,8% de las que presentaron lesiones cervicales tuvo menarca< 12 años; 76,5% relaciones sexuales < 15 años y el 82,35 % son gran multíparas. Conclusión: La prevalencia de lesiones precursoras de cáncer de cuello uterino es similar a estudios de otros países y menor a algunos estudios que se realizaron en Paraguay en población no indígena. Se encontró mayor porcentaje de lesiones en las edades medias, menarca temprana, inicio precoz de vida sexual y en multíparas. Palabras clave: Lesión intraepitelial cervical; cáncer de cérvix; citología; Paraguay; Servicios de Salud del Indígena.


Introduction: Cervical cancer is one of the most serious pathologies in the life of women. It caused 266 000 deaths in women due to this pathology in 2012, 85% in low and middle income countries. Objective: To determine the prevalence of precursor lesions of cervical cancer and sexual/reproductive antecedents of natives of Caaguazú during the years 2015 to 2017. Materials and methods: An observational, descriptive, cross-sectional study with non-probabilistic sampling was carried out. Indigenous people registered in the Cervical Pathology Program were studied. The data obtained were entered in Microsoft Excel © 2016, STATA® 14.0 was used for the analysis. The results were presented in tables and graphs. Results: The study included 129 indigenous people with an average age of 26 ± 10 years. The prevalence of precursor lesions of cervical cancer was 13.18%. The most frequently found lesions in order of frequency were ASCUS 10.08%; CIN I 2.32%; CIN II 0.77%; no CIN III was observed, nor carcinoma in situ. The ages in which they occurred most frequently were between 25 and 44 years in 70.59%. 58.8% of those who presented cervical lesions had menarche <12 years; 76.5% sexual intercourse <15 years and 82.35% are large multiparous. Conclusion: The prevalence of precursor lesions of cervical cancer is similar to studies from other countries and less than some studies that were conducted in Paraguay in a non-indigenous population. A higher percentage of lesions was found in the middle ages, early menarche, and early onset of sexual life and in multiparous women. Keywords: Cervical intraepithelial lesion; cervical cancer; cytology; Paraguay; Indigenous Health Services.


Subject(s)
Humans , Female , Child , Adolescent , Adult , Middle Aged , Precancerous Conditions/epidemiology , Uterine Cervical Neoplasms/epidemiology , Health of Indigenous Peoples , Paraguay/epidemiology , Sexual Behavior , Prevalence , Cross-Sectional Studies
11.
Arch. Health Sci. (Online) ; 25(2): 38-41, 20/07/2018.
Article in Portuguese | LILACS (Americas) | ID: biblio-1046455

ABSTRACT

Introdução: O câncer de colo do útero ainda é um sério problema de saúde pública em nosso país. Aparece em terceiro lugar entre os tipos de câncer mais comum entre as mulheres. Vários são os fatores envolvidos na etiologia desse câncer e suas lesões precursoras. Objetivo: Verificar os principais cofatores associados às alterações cervicouterinas. Casuística e Métodos: Trata-se de um estudo analítico e documental, realizado em um laboratório do município de Surubim-PE, incluindo resultados de exames citopatológicos do período de janeiro de 2014 a dezembro de 2015. Os dados foram avaliados pelo programa PRISM versão 7.0, por meio do teste Qui-quadrado, com intervalo de confiança 95% e razão de prevalência (RP). Resultados: Foram incluídos 1.200 resultados de exames de mulheres na faixa etária entre 14 e 78 anos. Quarenta e três por cento das mulheres pertenciam à faixa etária entre 31 e 47 anos e 86,6% haviam realizado seu último exame citopatológico a menos de três anos. A faixa etária entre 14 e 30 anos esteve associada a um maior risco para o desenvolvimento das anormalidades cervicais (p< 0,001 e OR 2,9). Mulheres que realizaram o exame citopatológico a menos de três anos apresentaram uma maior associação com a presença de lesões intraepiteliais escamosas de baixo grau (LSIL) e atipias escamosas (p < 0,0001 e OR 11,3). A lesão intraepitelial escamosa de baixo grau foi a anormalidade cervical de maior frequência, correspondendo a 46,3%. Mulheres com presença de Gardnerella vaginalis e/ou Mobiluncus spp. apresentaram associação com a presença de anormalidades cervicais (p< 0,0001). Conclusão: Mulheres abaixo de 30 anos, que realizaram exame citopatológico a menos de três anos ou apresentam Gardnerella vaginalis e/ou Mobiluncus spp.devem ser acompanhadas quanto aos possíveis riscos associados ao desenvolvimentode alterações cervicouterinas.


Introduction: Cervical cancer is still a serious public health problem in our country. It appears third among the most common types of cancer among women. Several are the factors involved in the etiology of this cancer and its precursor lesions. Objective: Verify the main cofactors associated with the changes in the cervix of the uterus. Patients and Methods:This is an analytical and documentary study, carried out in a laboratory in the municipality of Surubim-PE, including results of cytopathological exams from January 2014 to December 2015. Data were evaluated using the software PRISM version 7.0, by the Chi-square test, with 95% confidence interval and prevalence ratio (PR). Results: We included 1,200 tests results of women in the age between 14 and 78 years. Forty-three percent of the women were in the age group from 31 to 47 years and 86.6% had performed their last cytopathological examination less than three years. The age group ranging from 14 to 30 years was associated with a higher risk for the development of cervical abnormalities (p< 0.001 and OR 2.9). Women who underwent cytopathological examination less than three years presented a greater association with the presence of low squamous intraepithelial lesions (LSIL) and squamous atypia (p< 0.0001 and OR 11.3). The low-grade squamous intraepithelial lesion was the most frequent cervical abnormality, corresponding to 46.3%. Conclusion: Women under 30 years, who performed cytopathological examination at less than three years or present Gardnerella vaginalis and / or Mobiluncus spp. should be accompanied for the possible risks associated with the development of the changes in the cervix of uterus.


Subject(s)
Humans , Female , Adolescent , Adult , Middle Aged , Aged , Papillomaviridae , Pathology/statistics & numerical data , Uterine Cervical Neoplasms/epidemiology , Gardnerella vaginalis/pathogenicity , Squamous Intraepithelial Lesions of the Cervix/epidemiology
12.
Rev. pesqui. cuid. fundam. (Online) ; 10(3): 877-888, jul.-set. 2018. tab
Article in English, Portuguese | LILACS (Americas), BDENF | ID: biblio-906843

ABSTRACT

Objective: The leading purpose has been to identify the main publications related to social iniquity and mortality related to breast cancer (BC) and/or cervical cancer (CC), while investigating the type of association between the triggering factor and the case outcome. Methods: It is an Integrative Literature Review from the articles searching in the Medline, Lilacs, PubMed and Scielo databases. A total of 3,439 studies were obtained, from which only 85 have met the inclusion criteria. Results: The vast majority of the studies have found an association between high socioeconomic status and mortality by BC and also between low socioeconomic status and mortality by CC. The principal indicators used to evaluate these associations were as follows: education, income/poverty and labor market. Conclusion: Areas with high social iniquity have higher mortality rates related to CC, while those with higher socioeconomic status exhibit high mortality rates related to BC. These phenomena have several explanations: personal lifestyle, offer and accessibility to screening services and/or treatment, social stratification based on the economic model adopted in the country


Objetivo: Identificar as principais publicações relacionadas à iniquidade social e mortalidade por câncer de mama (CAM) e/ou colo do útero (CCU) e investigar o tipo de associação existente entre fator e desfecho. Método: Revisão Integrativa de Literatura a partir da busca de artigos nas bases Medline, Lilacs, PubMed e Scielo. Obteve-se 3.439 estudos, destes apenas 85 atendiam aos critérios de inclusão. Resultados: A maioria dos estudos encontrou associação entre alto nível socioeconômico e mortalidade CAM e entre baixo nível socioeconômico e mortalidade por CCU. Educação, renda/pobreza e mercado de trabalho foram os principais indicadores utilizados para avaliação dessas associações. Conclusão: Áreas com grande desigualdade social apresentam maior mortalidade por CCU enquanto aquelas com melhor nível socioeconômico exibem altas taxas de mortalidade por CAM. Estes fenômenos possuem várias explicações: estilo de vida dos indivíduos, oferta e acessibilidade aos serviços de rastreamento e/ou tratamento, estratificação social baseada no modelo econômico do país


Objetivo: Identificar las principales publicaciones relacionadas con la desigualdad social y la mortalidad por cáncer de mama (CAM) y/o el cuello uterino (CCU) e investigan el tipo de asociación entre el factor y el resultado. Método: una revisión integradora de la literatura de la búsqueda de artículos en el Medline, Lilacs, PubMed y Scielo. Obtenido 3.439 estudios, de éstos sólo 85 cumplieron con los criterios de inclusión. Resultados: La mayoría de los estudios encontraron una asociación entre el nivel socioeconómico alto y el CAM y la mortalidad entre el bajo nivel socioeconómico y la mortalidad por cáncer de cuello uterino. Educación, ingresos/pobreza y el mercado de trabajo fueron los principales indicadores utilizados para evaluar estas asociaciones. Conclusión: Las áreas con gran desigualdad social tienen mayores tasas de mortalidad por cáncer de cuello de útero, mientras que aquellos con mayor nivel socioeconómico presentan altas tasas de mortalidad por CAM. Estos fenómenos tienen varias explicaciones: el estilo de vida de los individuos, la oferta y la accesibilidad de los servicios de seguimiento y / o tratamiento, la estratificación social basada en el modelo económico del país


Subject(s)
Humans , Female , Breast Neoplasms/epidemiology , Health Status Disparities , Socioeconomic Factors , Uterine Cervical Neoplasms/epidemiology , Review Literature as Topic
13.
Medisan ; 22(5)mayo 2018. tab
Article in Spanish | LILACS (Americas) | ID: biblio-955036

ABSTRACT

Se realizó un estudio descriptivo y transversal de 125 pacientes, atendidas en la Consulta de Patología de Cuello, perteneciente al área de salud del Policlínico Universitario Municipal de Santiago de Cuba, durante el 2016, con vistas a describir los principales factores que propiciaron la aparición del cáncer cervicouterino. En la serie predominaron la neoplasia intracervical de grado I, la cervicitis crónica y las mujeres que comenzaron sus relaciones sexuales a los 15-19 años de edad (68,8 por ciento). Resultó significativa la presencia de leucorrea, sangrado poscoital y el virus del papiloma humano como antecedente de infección de transmisión sexual. Se destacó el papel negativo del cambio frecuente de pareja. Quedó demostrada la necesidad de que los profesionales de la salud consoliden sus conocimientos teóricos y prácticos sobre el cáncer cervicouterino, con énfasis en la educación sexual y reproductiva de las féminas, a través de la promoción y prevención de salud en la atención primaria


A descriptive and cross-sectional study of 125 patients, assisted in the Neck Pathology Service, belonging to the health area of the Municipal University Polyclinic in Santiago de Cuba, was carried out during 2016, aimed at describing the main factors that favored the emergence of cervical cancer. In the series there was a prevalence of grade I intracervical neoplasm, chronic cervicitis and women whose sexual relationships began at 15-19 years (68.8 percent). The presence of leukorrhea, postcoital bledding and human papilloma virus as history of sexual transmitted infection was significant. The necessity that health professionals consolidate their theoretical and practical knowledge on cervical cancer, with emphasis in the sexual and reproductive education of women, through the promotion and health prevention in primary care was demonstrated


Subject(s)
Humans , Female , Adolescent , Adult , Uterine Cervical Neoplasms/diagnosis , Uterine Cervical Neoplasms/prevention & control , Uterine Cervical Neoplasms/epidemiology , Primary Health Care , Cross-Sectional Studies , Risk Factors
15.
Rev. Bras. Saúde Mater. Infant. (Online) ; 17(4): 637-643, Oct.-Dec. 2017. tab
Article in English | LILACS (Americas) | ID: biblio-1013057

ABSTRACT

Abstract Objectives: to identify factors associated with abnormal cytopathological test uterine cervix. Methods: it is a analytical study with the participation of 390 women who presented abnormal cytopathological from a city in the state of Paraná in 2012. They were randomly selected through sampling plan. Sociodemographic information such as age, marital status, education level and ethnicity were considered independent variables while the high or low-grade cytological lesions as dependent variable. We analyzed the data statistically by Yates Corrected test, Fisher exact test and measures of association by odds ratio. For all analyzes was considered significance level of 5% and 95% confidence interval. Results: the mean age was 38.8 years, 72.9% were married or common-law marriage, 49.7% with low education level and 87.4% race/color white. HPV contamination was detected in 49.7% of women and high-grade cytological lesions in 18.2%. The low educa-tional level (95%OR=4.07) and non-white ethnicity (95%OR=2.22) were strongly associated with the development to cervical lesions (p<0.05). Conclusions: sociodemoghaphic characteristics were crucial to high-risk lesions and development of cervical cancer, especially in women with low educational level and race/color black or brown. These results confirm the persistence of diseases related to preventable and avoidable causes in the country.


Resumo Objetivos: identificar os fatores associados com alterações do exame citopatológico cérvico-uterino. Métodos: trata-se de um estudo analítico com participação de 390 mulheres que apresen-taram alterações citopatológicas em município do Estado do Paraná no período de 2012. Elas foram selecionadas aleatoriamente através de plano amostral. Informações sociode-mográficas como idade, estado civil, grau de escolaridade e etnia foram consideradas variáveis independentes enquanto que o alto ou baixo grau de lesão citológica como variável dependente. Analisaram-se os dados estatisticamente pelos Testes de Yates corrigido e Fisher e medidas de associação pela odds ratio. Para todas as análises considerou nível de significância de 5% e intervalo de confiança 95%. Resultados: a idade média foi de 38,8 anos sendo a maioria casada ou união estável (72,8%) e com baixa escolaridade (42,8%) e raça/cor branca (87,4%). A contaminação pelo HPV foi detectada em 49,7% das mulheres e lesões citológicas de alto grau em 18,2%. A baixa escolaridade (OR95%=4,07) e etnia não branca (OR95%=2,22) estiveram fortemente associadas ao desenvolvimento às lesões de colo uterino (p<0,05). Conclusão: características sociodemográficas foram determinantes para lesões de alto risco e desenvolvimento de câncer de colo uterino, especialmente nas mulheres de baixa escolaridade e raça/cor negra ou parda. Estes resultados confirmam a persistência de doenças por causas evitáveis e reduzíveis no país.


Subject(s)
Humans , Female , Uterine Cervical Neoplasms/epidemiology , Cervix Uteri/pathology , Papillomavirus Infections , Adenocarcinoma in Situ , Health Promotion , Socioeconomic Factors , Brazil , Cervical Intraepithelial Neoplasia , Early Detection of Cancer
16.
Rev. chil. obstet. ginecol ; 82(2): 144-152, abr. 2017.
Article in Spanish | LILACS (Americas) | ID: biblio-844559

ABSTRACT

El cáncer es un problema de salud pública mundial y su incidencia sigue elevándose. El 90 a 95% de las causas se deben a factores externos, de esos factores externos, el cigarrillo representa el 20 a 25%. La Agencia Internacional para la Investigación del Cáncer (IARC) han evaluado 62 de los 5.000 compuestos químicos del tabaco o cigarrillo, siendo considerados con suficientes evidencias como carcinogénicos tanto para humanos como para animales. Entre los canceres que han sido asociados con el consumo del cigarrillo, se encuentra el Cáncer del Cuello Uterino (CaCU). El CaCu está asociado a la infección del Virus del Papiloma Humano, sin embargo, hay fuerte evidencias que el cigarrillo es un factor de riesgo independiente en la origen y evolución del CaCU.


Cancer is a worldwide public health problem and its incidence is increasing. External factors are the 90-95% of the causes, cigarette represents the 20-25%. International Agency for Cancer Research has evaluated 62 of the 5.000 cigarette or tobacco chemical compounds; they have been considered with enough evidences as carcinogenic. Among the cancers that have been associated to the cigarette or tobacco, the Cancer of the Cervix (CaC) is one of them. The CaC is associated to the infection of the Human Papillomavirus, however, there are strong evidences that support the cigarette as an independent risk factor in the origin and evolution of the CaC.


Subject(s)
Humans , Female , Tobacco Products/adverse effects , Tobacco/adverse effects , Uterine Cervical Neoplasms/epidemiology
17.
Rev. chil. obstet. ginecol. (En línea) ; 82(2): 232-240, abr. 2017.
Article in Spanish | LILACS (Americas) | ID: biblio-899898

ABSTRACT

El cáncer es un problema de salud pública mundial y su incidencia sigue elevándose. El 90 a 95% de las causas se deben a factores externos, de esos factores externos, el cigarrillo representa el 20 a 25%. La Agencia Internacional para la Investigación del Cáncer (IARC) han evaluado 62 de los 5.000 compuestos químicos del tabaco o cigarrillo, siendo considerados con suficientes evidencias como carcinogénicos tanto para humanos como para animales. Entre los canceres que han sido asociados con el consumo del cigarrillo, se encuentra el Cáncer del Cuello Uterino (CaCU). El CaCu está asociado a la infección del Virus del Papiloma Humano, sin embargo, hay fuerte evidencias que el cigarrillo es un factor de riesgo independiente en la origen y evolución del CaCU.


Cancer is a worldwide public health problem and its incidence is increasing. External factors are the 90-95% of the causes, cigarette represents the 20-25%. International Agency for Cancer Research has evaluated 62 of the 5.000 cigarette or tobacco chemical compounds; they have been considered with enough evidences as carcinogenic. Among the cancers that have been associated to the cigarette or tobacco, the Cancer of the Cervix (CaC) is one of them. The CaC is associated to the infection of the Human Papillomavirus, however, there are strong evidences that support the cigarette as an independent risk factor in the origin and evolution of the CaC.


Subject(s)
Humans , Female , Tobacco/adverse effects , Uterine Cervical Neoplasms/epidemiology , Tobacco Products/adverse effects
18.
Rev. chil. obstet. ginecol ; 82(1): 26-34, feb. 2017. tab
Article in Spanish | LILACS (Americas) | ID: biblio-844534

ABSTRACT

Introducción: El cáncer de cuello uterino es un problema de salud pública mundial, y es la segunda causa de muerte en el Perú; su estudio se ha realizado más en poblaciones de grandes ciudades, dejando de lado otras poblaciones que podrían tener un riesgo significativo. Objetivo: Determinar la prevalencia y los factores asociados a los hallazgos citológicos anormales de cuello uterino en las mujeres de pescadores de una ciudad del norte peruano. Métodos: Investigación transversal analítica de datos secundarios, se realizó un muestreo por conveniencia en las mujeres con vida sexual activa de una población semi urbana del norte peruano. La variable principal fue el hallazgo de lesiones pre invasoras e invasoras del cuello uterino según la citología observada, se cruzó con otras variables sociales, ginecológicas y sexuales; encontrando estadísticos de asociación crudos y ajustados. Resultados: De las 144 encuestadas, el 20% tuvo una alteración citológica y el 26% no se habían realizado la prueba hace más de 3 años. El 14% fue positivo para lesión escamosa intra epitelial de bajo grado, el 1% tuvo un carcinoma escamoso invasor. Al realizar el análisis multivariado, se obtuvo una asociación entre lesión citológica y VPH (p<0,001), el tener inflamación severa (p<0,001), el tener un germen (p=0,001) y el haber iniciado las relaciones sexuales a los 14 años o menos (p=0,024), ajustado por el usar anticonceptivos y el haberse realizado un Papanicolaou. Conclusiones: Se reporta algunos factores asociados en una población sexualmente activa, que reflejan una gran prevalencia de lesiones asociada a factores que deben ser intervenidos.


Introduction: Cervical cancer is a global public health problem, and is the second leading cause of death in Peru; the study was conducted more in populations of large cities, leaving aside other populations that could have a significant risk. Objective: To determine the prevalence and factors associated with abnormal cervical cytologic findings in women of fishermen in a city in northern Peru. Methods: Cross-sectional analytical research of secondary data, convenience sampling was performed in women with active sex life in a semi urban population of northern Peru. The principal variable was the finding of pre invasive and invasive cervical lesions observed by cytology, crossed with other social, gynecological and sexual variables; statistical finding of crude and adjusted association. Results: Of the 144 respondents, 20% had a cytological alteration and the 26% had not taken the test over 3 years ago. 14% were positive for squamous intra epithelial lesion low grade, 1% had an invasive squamous carcinoma. When performing multivariate analysis, an association between cytological lesion and HPV (p<0.001), having severe inflammation (p<0.001), having a germ (p=0.001) and initiating sexual intercourse at age 14 or less (p=0.024), adjusted for contraceptive use and Pap tests have been done. Conclusions: Some associated factors in a sexually active population, reflecting a high prevalence of injury associated with factors that have to be operated.


Subject(s)
Humans , Female , Adolescent , Adult , Young Adult , Cervix Uteri/pathology , Papanicolaou Test , Uterine Cervical Neoplasms/epidemiology , Uterine Cervical Neoplasms/pathology , Cross-Sectional Studies , Fisheries , Multivariate Analysis , Peru/epidemiology , Prevalence , Risk Factors , Surveys and Questionnaires
19.
Medicina (Ribeiräo Preto) ; 50(1)jan.-fev. 2017.
Article in Portuguese | LILACS (Americas) | ID: biblio-833773

ABSTRACT

Modelo do estudo: Estudo de Prevalência. Objetivo do estudo: Conhecer a prevalência dos resultados alterados dos exames preventivos para câncer do colo do útero e a sua regularidade na coleta. Metodologia: Estudo observacional, transversal e retrospectivo. Foram estudadas 3.425 mulheres usuárias do Sistema Único de Saúde e 9.436 exames citopatológicos de novembro de 2003 a janeiro de 2014. Resultados: A mediana da idade foi de 35 anos (25,0 - 46,0, percentil 25 a 75%). No primeiro exame citopatológico, 2,7% das mulheres apresentaram alterações em células epiteliais. As Células escamosas atípicas de significado incerto (ASC-US) (n=54; 1,7%) e as lesões intra-epiteliais de baixo grau (LIEBG) (n=24; 0,7%) foram as mais frequentes. Ao longo do período observado houveram 87 novas alterações citopatológicas, totalizando 173 exames alterados em 9.436 analisados. Quanto a regularidade, 58,5% pacientes repetiram a segunda coleta. Conclusões: Houve um perfil predominante de mulheres jovens, sendo o diagnóstico de ASC-US o mais frequente. A flora bacteriana mais frequente foi Lactobacillus principalmente em mulheres jovens. (AU)


Study Model: Prevalence Study. Study objective: To determine the prevalence of the abnormal cervical cancer screening test (PAP) and regularity in repeat it. Methods: An observational, cross-sectional and retrospective study. 3,425 women, users of the Brazilian Unified Health System, and 9,436 cytopathology, conducted from November 2003 to January 2014, were studied. Results: The median age was 35 years (25.0 to 46.0, 25 to 75% percentile). In the first PAP, 2.7% of women examined had alterations in epithelial cells. The atypical squamous cells of uncertain significance (ASC-US) (n = 54; 1.7%), and low-grade intraepithelial lesion (LSIL) (n = 24; 0.7%) were the most frequent alterations found. During the observed period, 87 new abnormal PAPs were found, totalling 173 altered tests in 9436 analysed. Regarding regularity of test, 58.5% patients repeated the second PAP. Conclusions: There was a preferential profile of young women, and the diagnosis of ASC-US was the most frequently found. Lactobacillus, especially in young women, was the main bacterial flora. (AU)


Subject(s)
Humans , Female , Adult , Middle Aged , DNA Probes, HPV , Uterine Cervical Neoplasms/epidemiology , Vaginal Smears
20.
Rev. chil. obstet. ginecol. (En línea) ; 82(1): 26-34, feb. 2017. tab
Article in Spanish | LILACS (Americas) | ID: biblio-899873

ABSTRACT

Introducción: El cáncer de cuello uterino es un problema de salud pública mundial, y es la segunda causa de muerte en el Perú; su estudio se ha realizado más en poblaciones de grandes ciudades, dejando de lado otras poblaciones que podrían tener un riesgo significativo. Objetivo: Determinar la prevalencia y los factores asociados a los hallazgos citológicos anormales de cuello uterino en las mujeres de pescadores de una ciudad del norte peruano. Métodos: Investigación transversal analítica de datos secundarios, se realizó un muestreo por conveniencia en las mujeres con vida sexual activa de una población semi urbana del norte peruano. La variable principal fue el hallazgo de lesiones pre invasoras e invasoras del cuello uterino según la citología observada, se cruzó con otras variables sociales, ginecológicas y sexuales; encontrando estadísticos de asociación crudos y ajustados. Resultados: De las 144 encuestadas, el 20% tuvo una alteración citológica y el 26% no se habían realizado la prueba hace más de 3 años. El 14% fue positivo para lesión escamosa intra epitelial de bajo grado, el 1% tuvo un carcinoma escamoso invasor. Al realizar el análisis multivariado, se obtuvo una asociación entre lesión citológica y VPH (p<0,001), el tener inflamación severa (p<0,001), el tener un germen (p=0,001) y el haber iniciado las relaciones sexuales a los 14 años o menos (p=0,024), ajustado por el usar anticonceptivos y el haberse realizado un Papanicolaou. Conclusiones: Se reporta algunos factores asociados en una población sexualmente activa, que reflejan una gran prevalencia de lesiones asociada a factores que deben ser intervenidos.


Introduction: Cervical cancer is a global public health problem, and is the second leading cause of death in Peru; the study was conducted more in populations of large cities, leaving aside other populations that could have a significant risk. Objective: To determine the prevalence and factors associated with abnormal cervical cytologic findings in women of fishermen in a city in northern Peru. Methods: Cross-sectional analytical research of secondary data, convenience sampling was performed in women with active sex life in a semi urban population of northern Peru. The principal variable was the finding of pre invasive and invasive cervical lesions observed by cytology, crossed with other social, gynecological and sexual variables; statistical finding of crude and adjusted association. Results: Of the 144 respondents, 20% had a cytological alteration and the 26% had not taken the test over 3 years ago. 14% were positive for squamous intra epithelial lesion low grade, 1% had an invasive squamous carcinoma. When performing multivariate analysis, an association between cytological lesion and HPV (p<0.001), having severe inflammation (p<0.001), having a germ (p=0.001) and initiating sexual intercourse at age 14 or less (p=0.024), adjusted for contraceptive use and Pap tests have been done. Conclusions: Some associated factors in a sexually active population, reflecting a high prevalence of injury associated with factors that have to be operated.


Subject(s)
Humans , Female , Uterine Cervical Neoplasms/pathology , Uterine Cervical Neoplasms/epidemiology , Peru/epidemiology , Cervix Uteri/cytology , Prevalence , Cross-Sectional Studies , Multivariate Analysis , Surveys and Questionnaires , Risk Factors , Fisheries , Papanicolaou Test/methods
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