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1.
Cad. Saúde Pública (Online) ; 37(5): e00078820, 2021. tab, graf
Article in English | LILACS | ID: biblio-1249447

ABSTRACT

Abstract: Historically, human migrations have determined the spread of many infectious diseases by promoting the emergence of temporal outbreaks between populations. We aimed to analyze health indicators, expenditure, and disability caused by tuberculosis (TB) and HIV/AIDS burden under the Colombian-Venezuelan migration flow focusing on the Northeastern border. A retrospective study was conducted using TB and HIV/AIDS data since 2009. We consolidated a database using official reports from the Colombian Surveillance System, World Health Organization, Indexmundi, the Global Health Observatory, IHME HIV atlas, and Joint United Nations Programme on HIV/AIDS (UNAIDS). Disability metrics regarding DALYs (disability adjusted life years) and YLDs (years lived with disability), were compared between countries. Mapping was performed on ArcGIS using official migration data of Venezuelan citizens. Our results indicate that TB profiles from Colombia and Venezuela are identical in terms of disease burden, except for an increase in TB incidence in the Colombian-Venezuelan border departments in recent years, concomitantly with the massive Venezuelan immigration since 2005. We identified a four-fold underfunding for the TB program in Venezuela, which might explain the low-testing rates for cases of multidrug-resistant TB (67%) and HIV/AIDS (60%), as well as extended hospital stays (150 days). We found a significant increase in DALYs of HIV/AIDS patients in Venezuela, specifically, 362.35 compared to 265.37 observed in Colombia during 2017. This study suggests that the Venezuelan massive migration and program underfunding might exacerbate the dual burden of TB and HIV in Colombia, especially towards the Colombian‐Venezuelan border.


Resumen: Históricamente, las migraciones humanas han determinado la expansión de muchas enfermedades infecciosas, promoviendo el surgimiento de brotes temporales en la población. Nuestro objetivo fue analizar indicadores de salud, gastos, así como la discapacidad causada por la tuberculosis (TB) y la carga del VIH/SIDA ante el flujo migratorio entre Colombia-Venezuela, centrándose en los departamentos fronterizos del nordeste. Se realizó un estudio retrospectivo usando datos sobre TB y VIH/SIDA desde 2009. Consolidamos una base de datos usando informes oficiales del Sistema de Vigilancia Colombiano, Organización Mundial de la Salud, Indexmundi, Observatorio Global de la Salud, IHME HIV atlas, y Programa Conjunto de las Naciones Unidas sobre el VIH/SIDA (ONUSIDA). Se midió la discapacidad en términos del DALYs (incapacidad ajustada por años de vida) y YLDs (años vividos con discapacidad) y se compararon entre ambos países. El mapeo se realizó en ArcGIS, usando datos oficiales de migración de ciudadanos venezolanos. Nuestros resultados indican que los perfiles de TB de Colombia y Venezuela son idénticos, en lo que se refiere a la carga de la enfermedad, excepto por el incremento en la incidencia de TB en los departamentos fronterizos de la frontera entre Colombia y Venezuela en años recientes, concomitantemente con la inmigración masiva venezolana desde 2005. Identificamos una cuadruplicación de la subfinanciación para el programa de TB en Venezuela, que podría explicar las bajas tasas de test para los casos multirresistentes a medicamentos contra la TB (67%) y VIH/SIDA (60%), al igual que las estancias prolongadas en el hospital (150 días). Hallamos un incremento significativo en DALYs de pacientes con VIH/SIDA en Venezuela, específicamente, 362,35 comparados con los 265,37 observados en Colombia durante 2017. Este estudio sugiere que la migración venezolana masiva y la subfinanciación del programa podrían haber exacerbado la doble carga de la TB y el VIH en Colombia, especialmente a través de la frontera entre Colombia y Venezuela.


Resumo: Historicamente, as migrações humanas determinaram a propagação de muitas doenças infecciosas ao facilitar surtos temporais entre populações. O estudo buscou analisar os indicadores sanitários e os gastos e taxas de incapacidade relacionados à tuberculose (TB) e à carga de HIV/aids no fluxo migratório entre Colômbia e Venezuela, com destaque para os departamentos (estados) da fronteira nordeste. Foi realizado um estudo retrospectivo de dados sobre TB e HIV/aids desde 2009. Consolidamos uma base de dados a partir de relatórios do Sistema de Vigilância da Colômbia, Organização Mundial da Saúde, Indexmundi, Observatório de Saúde Global, IHME HIV Atlas e Programa Conjunto das Nações Unidas sobre HIV/AIDS (UNAIDS). As métricas de incapacidade em termos de AVAIs (anos de vida ajustados para incapacidade) e AVIs (anos vividos com incapacidade) foram comparadas entre os dois países. O mapeamento foi realizado no ArcGIS, com dados oficiais sobre migração de cidadãos venezuelanos. Nossos resultados indicam que os perfis de TB da Colômbia e da Venezuela são idênticos em termos de carga de doença, exceto por um aumento da incidência de TB nos departamentos na fronteira entre os dois países em anos recentes, concomitantemente com a imigração venezuelana maciça desde 2005. Identificamos um subfinanciamento (por um fator de quatro) no programa de tuberculose da Venezuela, o que pode explicar as baixas taxas de testagem para casos de TB multirresistente (67%) e HIV/aids (60%), além das internações hospitalares prolongadas (150 dias). Encontramos um aumento significativo de AVAIs em pacientes de HIV/aids na Venezuela, especificamente 362,35 comparado com 265,37 na Colômbia em 2017. O estudo sugere que a migração maciça venezuelana e o subfinanciamento podem exacerbar a carga dupla de TB e HIV na Colômbia, principalmente na fronteira com a Venezuela.


Subject(s)
Humans , Tuberculosis/epidemiology , HIV Infections/epidemiology , Venezuela/epidemiology , Brazil , Retrospective Studies , Colombia/epidemiology , Emigration and Immigration
2.
Mem. Inst. Oswaldo Cruz ; 116: e210203, 2021. tab, graf
Article in English | LILACS | ID: biblio-1346579

ABSTRACT

BACKGROUND Paracoccidioidomycosis (PCM) is a systemic mycosis endemic to Latin America. Etiological agents are Paracoccidioides species that diverge phylogenetically throughout South America. OBJECTIVES This study aimed to document the epidemiology of PCM in Venezuela. METHODS We have performed a retrospective cross-sectional descriptive study in 31,081 clinical records of patients from two reference centres during 65 years (1954-2019). FINDINGS PCM diagnosis was confirmed in 745 patients. Chronic PCM was the most prevalent form (90.06% cases); 80.67% were male and the most affected age range was 41-60. Farming and construction were the most prevalent occupation and Miranda State had a higher prevalence. Lung and skin were the most affected organs, followed by oral manifestations. Direct examination, culture and serology showed a high sensibility, and no statistical difference was observed among the diagnostic tools. Out of 17 Paracoccidioides isolates genotyped from Venezuela, one was typed as Paracoccidioides americana and 16 as Paracoccidioides venezuelensis. MAIN CONCLUSIONS Clinical manifestations observed, information about the epidemiology and molecular profile is essential not only for diagnosis but also for understanding therapeutic responses to mycotic drugs and prognosis. Therefore, it is necessary to sequence all positive isolated strains in order to confirm the dominance of P. venezuelensis in Venezuela.


Subject(s)
Humans , Male , Paracoccidioides/genetics , Paracoccidioidomycosis/genetics , Paracoccidioidomycosis/epidemiology , Venezuela/epidemiology , Cross-Sectional Studies , Retrospective Studies
3.
Medwave ; 20(10): e8064, 18 nov. 2020.
Article in English, Spanish | LILACS | ID: biblio-1145807

ABSTRACT

Introducción La psoriasis es una enfermedad crónica que compromete la piel, padecida por cerca de 125 millones de personas en todo el mundo. En un grupo determinado de pacientes, también puede afectar el sistema articular. Para el control y seguimiento de los pacientes con psoriasis se estableció la aplicación de los índices de severidad del área de psoriasis y de calidad de vida dermatológica. Ambos parámetros son necesarios para el inicio de terapia biológica, según lo establecido en la guía de manejo de psoriasis (2015) del comité nacional de enfermedades reumatológicas, inmunológicas y de metabolismo óseo del Instituto Venezolano de los Seguros Sociales. Objetivo Caracterizar las variables clínicas, epidemiológicas y la prescripción de terapia biológica en los pacientes con psoriasis que acceden al programa de dispensación de alto costo de la farmacia del Instituto Venezolano de los Seguros Sociales. Método Es un estudio descriptivo, transversal. Resultados Se evaluaron 374 expedientes, donde el sexo masculino fue más frecuente con 56,1% (p < 0,001), provenientes en su mayoría de la ciudad de Caracas, en la comparación de los grupos de edad con el sexo, se observó que existía una diferencia entre estos (p < 0,05). El 57,5% usó previamente metotrexato; 6,68% biológicos; 3,2% esteroides tópicos y 31% no reportó qué tipo de terapia previa recibía. Dentro de las presentaciones clínicas, 70% correspondió a la psoriasis en placa. El 79% de los pacientes presentaba actividad moderada según el índice de la severidad del área de psoriasis, y al 11% se les realizó el índice de calidad de vida dermatológica, de los cuales 39% presentaban un efecto extremadamente importante. El rango anérgico de la prueba de Mantoux representó 70,9% de los casos, donde al 0,3% le fue realizado la prueba de Booster, y la radiografía de tórax se reportó normal en 95%. El medicamento biológico más demandado fue el etanercept con 52% de los casos. Conclusiones El sexo masculino y su relación con la psoriasis fue un hallazgo de importancia, como también se evidenció la necesidad de mejorar los componentes administrativos en la gestión de los formatos de solicitud de medicamentos y fortalecer la aplicación de la clinimetría con elemento de buena práctica médica.


Introduction Psoriasis is a chronic disease that affects the skin. One hundred twenty-five million people around the world suffer from this condition. In specific groups of patients, the joints may also be involved. To control and follow-up patients with psoriasis, psoriasis area severity and dermatological quality of life measurements were established. Both parameters are necessary for the initiation of biological therapy, as specified in the psoriasis management guide (2015) of the national committee of rheumatological, immunological, and bone metabolism diseases of the Venezuelan Institute of Social Security. Objective To characterize the clinical and epidemiological variables and the prescription of biological therapy in patients with psoriasis who access the high-cost dispensing program of the Venezuelan Institute Social Security (IVSS) pharmacy. Methods This is a descriptive, cross-sectional study. Results A total of 374 patient records were assessed. The male gender was more frequent, with 56.1% (p <0.001), mostly from Caracas city. In comparing age groups with sex, a difference among these was observed (p <0.05). 57.5% previously used methotrexate, 6.68% biological, 3.2% topical steroids, and 31% did not report which type of previous therapy they had received. Amongst the clinical presentations, 70% corresponded to plaque psoriasis. 79% of the patients presented moderate activity according to the Psoriasis Area and Severity Index (PASI): Eleven percent were assessed with the Dermatology Life Quality Index (DLQI); 39% of them reported an extremely important effect. The anergic range of the Mantoux test represented 70.9% of the cases, and 0.3% took the booster evaluation. Chest X-ray was reported normal in 95% of the cases. The most demanded biological medicine was etanercept, in 52% of the cases. Conclusions Male gender and its association with psoriasis was an important finding. The need to improve the administrative components in completing the medication request formats and strengthen clinical measurements and good medical practice was also found.


Subject(s)
Humans , Male , Psoriasis/drug therapy , Psoriasis/epidemiology , Quality of Life , Biological Therapy , Venezuela/epidemiology , Severity of Illness Index , Cross-Sectional Studies , Prescriptions
4.
Salud bienestar colect ; 4(2): 2-9, may.-ago. 2020.
Article in Spanish | LILACS | ID: biblio-1254370

ABSTRACT

En el presente trabajo se realiza una reflexión de la experiencia venezolana frente a la pandemia del COVID-19. Se parte del análisis del contexto económico previo y de las políticas públicas en salud y los cambios ocurridos en los últimos 20 años. La situación existente al inicio de la pandemia coloca al país en una gran vulnerabilidad, siendo una nación asediada con un bloqueo al acceso de cuentas en divisas fuera del país. Bloqueo en la venta e incautación de los recursos petroleros y de las finanzas públicas venezolanas existente en otros países. Déficit de combustibles como la gasolina. Caída de los precios del petróleo y con la imposibilidad de importar y exportar bienes y servicios. Las medidas tomadas ante la pandemia fueron: Decreto Presidencial de estado de alarma, cuarentena nacional consiente, distanciamiento social, uso obligatorio del tapaboca. Suspensión de la actividad laboral y la escolar presencial en todos los niveles. Detección precoz de posibles casos con la aplicación de pruebas rápidas masivamente. Control fronterizo con cuarentena obligatoria por 14 días y aplicación de pruebas de detección del COVID-19. Protección del empleo, suspensión de pago de alquileres de vivienda y locales comerciales entre otros. Se concluye que las decisiones tomadas por el gobierno nacional han sido exitosas para contener la propagación de la pandemia y mantener una baja mortalidad. El comportamiento de la población ha sido ejemplar. Finalmente en un mundo globalizado es necesario globalizar la solidaridad, fortalecer los estados nación versus las leyes del mercado para atender la salud.


This paper reflects on the Venezuelan experience in the face of the COVID-19 pandemic. It starts from the analysis of the previous economic context and of public health policies and the changes that have occurred in the last 20 years. The situation that existed at the beginning of the pandemic places the country in a highly vulnerable position, being a nation under siege with a block to the access of foreign currency accounts outside the country. Blockade in the sale and seizure of Venezuelan oil resources and public finances existing in other countries. Fuel deficit such as gasoline. Fall in oil prices and the impossibility of importing and exporting goods and services. The measures taken in the face of the pandemic were: Presidential Decree of alarm status, consenting national quarantine, social distancing, compulsory use of the mask. Suspension of work and school activity at all levels. Early detection of possible cases with the application of mass rapid tests. Border control with mandatory 14-day quarantine and application of COVID-19 screening tests. Protection of employment, suspension of payment of rent for housing and commercial premises, among others. It is concluded that the decisions made by the national government have been successful in containingthe spread of the pandemic and maintaining low mortality. The behavior of the population has been exemplary. Finally, in a globalized world it is necessary to globalize solidarity, strengthen nation states versus market laws to care for health.


Subject(s)
Humans , Socioeconomic Factors , Pandemics/economics , COVID-19/economics , Venezuela/epidemiology
5.
Acta toxicol. argent ; 28(1): 13-18, Apr. 2020. graf
Article in Spanish | LILACS | ID: biblio-1248664

ABSTRACT

Resumen Se describe un accidente causado por Tityus falconensis González-Sponga, 1974 (Scorpiones, Buthidae) en un indi viduo masculino de 48 años de edad. El evento catalogado clínicamente como un envenenamiento sin compromiso sistémico, con solo síntomas y signos locales (edema e hiperemia en halux y parestesia del área plantar del pie derecho); ocurrió en el ambiente antrópico (área de dormitorio) en la localidad rural de La Peña, Sierra de San Luis, estado Falcón, región nor-occidental de Venezuela.


Abstract We report an accident produced by Tityus falconensis González-Sponga, 1974 (Scorpiones, Buthidae) in a 48 years old male patient. The accident was considered clinically as an envenomation with no systemic compliance, with just local signs and symptoms (oedema and hyperemia in the halux and paresthesia of the plantar part of the right foot). The accident took place within the human environment (in dormitory) in the rural community of La Peña, Sierra de San Luis, Falcon state, North-Western region from Venezuela.


Subject(s)
Humans , Male , Middle Aged , Scorpion Venoms/toxicity , Scorpion Stings/epidemiology , Venezuela/epidemiology
6.
Rev. salud pública ; 22(2): e486366, mar.-abr. 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1127226

ABSTRACT

RESUMEN Objetivos Dimensionar la migración humana en la frontera sur entre Colombia y Venezuela (Departamento de Guainía), y caracterizar las condiciones sociales, de acceso y de atención en salud frente a la pandemia de COVID-19. Métodos Estudio mixto, epidemiológico y etnográfico. Se calcularon: tasa de migrantes venezolanos (según Migración Colombia al 31 de diciembre de 2019), acceso efectivo a atención médica y dotación en puestos de salud (según datos recolectados entre junio de 2017 y julio de 2019, en todos los puestos de salud de Guainía, mediante entrevistas semiestructuradas, observación participante y el uso de Google Earth™ y Wikiloc™). Los tiempos medianos se calcularon y graficaron en Stata™. Se describieron dinámicas culturales y de atención en salud a partir del trabajo de campo y de una permanente revisión documental. Resultados Guainía ocupa el puesto 23 en número total de venezolanos, pero es el cuarto departamento en densidad de venezolanos (14,4%). En ausencia del centro de salud de San José, en el río Guainía los tiempos medianos hasta la institución de referencia real son de 8,7 horas en invierno y 12,3 en verano y los casos complejos requieren remisión aérea. En el río Inírida, sin el centro de Chorro Bocón, los tiempos reales son de 11,9 horas en invierno y 16,1 en verano. Solo el 57% de los puestos de salud tenía insumos para manejar infección respiratoria aguda. Conclusiones Ante la llegada de COVID-19 a territorios sur-fronterizos, es necesario fortalecer inmediatamente servicios médicos y de salud pública para evitar elevadas tasas de letalidad.(AU)


ABSTRACT Objectives To size human migration on the southern border between Colombia and Venezuela (Guainía department), and characterize the social, access and health care conditions relevant to the COVID-19 pandemic. Methods Mixed epidemiological and ethnographic study. Rate of Venezuelan migrants was calculated according to Migration Colombia data until December 31st, 2019, also effective access to medical care, and provision of health posts were calculated, with information from each Guainía health post collected from June 2017 to June 2019, through semi-structured interviews, participant observations, Google Earth™ and Wikiloc™. Stata™ was used to calculate and graph median times of effective access. Cultural dynamics and health care conditions were described by the field work information and a permanent documentary review. Results Guainía is the 23rd department, according to the total number of Venezuelans, but the fourth in Venezuelans density (14,4%). In the Guainía river, the median times to the real reference health institution were 8,7 hours in winter and 12,3 in summer, and complex cases require air referrals. In the Inírida river, the median times to the real reference health institution were 11,9 hours in winter and 16,1 in summer. Only 57% of the health posts had supplies for acute respiratory infections. Conclusions Facing COVID-19 in south border territories, it is necessary to immediately strengthen medical and public health services to avoid high fatality rates.(AU)


Subject(s)
Humans , Health Infrastructure , Coronavirus Infections/epidemiology , Emigration and Immigration , Effective Access to Health Services/organization & administration , Venezuela/epidemiology , Epidemiologic Studies , Colombia/epidemiology , Health Services, Indigenous/organization & administration , Anthropology, Cultural
7.
Rev. salud pública ; 22(2): e211, mar.-abr. 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1139440

ABSTRACT

RESUMEN Objetivos Dimensionar la migración humana en la frontera sur entre Colombia y Venezuela (Departamento de Guainía), y caracterizar las condiciones sociales, de acceso y de atención en salud frente a la pandemia de COVID-19. Métodos Estudio mixto, epidemiológico y etnográfico. Se calcularon: tasa de migrantes venezolanos (según Migración Colombia al 31 de diciembre de 2019), acceso efectivo a atención médica y dotación en puestos de salud (según datos recolectados entre junio de 2017 y julio de 2019, en todos los puestos de salud de Guainía, mediante entrevistas semiestructuradas, observación participante y el uso de Google Earth™ y Wikiloc™). Los tiempos medianos se calcularon y graficaron en Stata™. Se describieron dinámicas culturales y de atención en salud a partir del trabajo de campo y de una permanente revisión documental. Resultados Guainía ocupa el puesto 23 en número total de venezolanos, pero es el cuarto departamento en densidad de venezolanos (14,4%). En ausencia del centro de salud de San José, en el río Guainía los tiempos medianos hasta la institución de referencia real son de 8,7 horas en invierno y 12,3 en verano y los casos complejos requieren remisión aérea. En el río Inírida, sin el centro de Chorro Bocón, los tiempos reales son de 11,9 horas en invierno y 16,1 en verano. Solo el 57% de los puestos de salud tenía insumos para manejar infección respiratoria aguda. Conclusiones Ante la llegada de COVID-19 a territorios sur-fronterizos, es necesario fortalecer inmediatamente servicios médicos y de salud pública para evitar elevadas tasas de letalidad.(AU)


ABSTRACT Objectives To size human migration on the southern border between Colombia and Venezuela (Guainía department), and characterize the social, access and health care conditions relevant to the COVID-19 pandemic. Methods Mixed epidemiological and ethnographic study. Rate of Venezuelan migrants was calculated according to Migration Colombia data until December 31st, 2019, also effective access to medical care, and provision of health posts were calculated, with information from each Guainía health post collected from June 2017 to June 2019, through semi-structured interviews, participant observations, Google Earth™ and Wikiloc™. Stata™ was used to calculate and graph median times of effective access. Cultural dynamics and health care conditions were described by the field work information and a permanent documentary review. Results Guainía is the 23rd department, according to the total number of Venezuelans, but the fourth in Venezuelans density (14,4%). In the Guainía river, the median times to the real reference health institution were 8,7 hours in winter and 12,3 in summer, and complex cases require air referrals. In the Inírida river, the median times to the real reference health institution were 11,9 hours in winter and 16,1 in summer. Only 57% of the health posts had supplies for acute respiratory infections. Conclusions Facing COVID-19 in south border territories, it is necessary to immediately strengthen medical and public health services to avoid high fatality rates.(AU)


Subject(s)
Humans , Health Infrastructure , Coronavirus Infections/epidemiology , Emigration and Immigration/trends , Effective Access to Health Services/organization & administration , Venezuela/epidemiology , Epidemiologic Studies , Colombia/epidemiology
8.
Article in English | LILACS, BBO | ID: biblio-1135487

ABSTRACT

Abstract Objective: To determine the prevalence of nasal septum perforation associated to Histoplasma sp. Material and Methods: A retrospective descriptive study was conducted with patients who developed nasal septum perforation associated to histoplasmosis. The diagnosis was made based on clinical manifestations and confirmed with mycological direct examination with Giemsa stain, culture, serologic tests (immunodiffusion method), and histopathology with hematoxylin-eosin, Grocott methenamine (GMS) and Periodic Acid-Schiff stain (PAS). Results: Out of 1654 medical records reviewed with diagnosis of histoplasmosis in the study period, we found 22 cases with nasal septum perforation. Autoimmune disease was present in 6 patients; all six were on immunosuppressive treatment. Two patients had HIV/AIDS, one of them had also paracoccidiodomycoses and the remaining had no apparent underlying disease or conditions. Conclusion: Physicians of endemic areas such as Venezuela, must consider this entity in the differential diagnosis with other diseases.


Subject(s)
Humans , Male , Female , Acquired Immunodeficiency Syndrome/pathology , Diagnosis, Differential , Nasal Septal Perforation/diagnostic imaging , Immunosuppressive Agents/therapeutic use , Mycoses/pathology , Autoimmune Diseases/pathology , Venezuela/epidemiology , Medical Records , Epidemiology, Descriptive , Retrospective Studies
9.
Rev. chil. salud pública ; 24(1): 30-39, 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1121731

ABSTRACT

INTRODUCCIÓN: Las infecciones de transmisión sexual (ITS) se expresan con mayor frecuencia en poblaciones marginadas, como lo son los ciudadanos que se encuentran en situación de calle y con problemas de drogadicción. MATERIALES Y MÉTODOS: Mediante un estudio de campo descriptivo retrospectivo, se determinó la prevalencia de las ITS que se detallan en los ciudadanos residentes de un Centro de Inclusión Social en Venezuela durante los años 2013 a 2018. Para ello, suero de 280 individuos fue analizado mediante la prueba ELISA de diferentes compañías biotecnológicas. RESULTADOS: 50 casos (17,8%) fueron reactivos a cualquiera de las enfermedades investigadas. El biomarcador de mayor prevalencia durante el lapso estudiado fue el antiHBc con 13,9% y las menores fueron HBsAg con 0,75%, VHC con 0,71% y Treponema pallidum con 2,85%, así como 2,14% para VIH. No se detectó ningun caso de HTLV. Del mismo modo, se observó una tasa de co-infección entre hepatitis B y VIH de 2,32%, entre hepatitis C y VIH de 1,5% y en dos años se consiguió co-infeccion de hepatitis B y Sífilis con 1,5% y 5,8% en el 2014 y 2018 respectivamente. DISCUSIÓN: Se encontró que los sujetos acogidos en el Centro de Inclusión Social son un grupo vulnerable a las ITS y las coinfecciones, por lo que deben llevarse a cabo campañas de preven-ción y pruebas de detección de estas enfermedades en dicha población.


INTRODUCTION: Sexually Transmitted Infections (STIs) are most frequently expressed in marginalized populations, such as as homeless individuals or those with substance abuse issues. MATERIALS AND METHODS: Through a retrospective descriptive study, the prevalence of various STDs was determined among residents of a Social Inclusion Center in Venezuela from 2013 to 2018. For this purpose, serum from 280 individuals were analyzed with ELISA tests from different biotech companies. RESULTS: 50 cases (17.86%) were sero-reactive to any of the STIs investigated. The most preva-lent biomarker during the study period studied was antiHBc (13.9%) and the lowest prevalen-ces were HBsAg with 0.75%, HCV with 0.71%, and Treponema pallidum with 2.85%, as well as 2.14% for HIV. No cases of HTLV were detected. Similarly, there was coinfection between hepatitis B and HIV in 2.32% of cases, between hepatitis C and HIV in 1.5%, and between syphillis and hepatitis in 1,5% and 5,8% of cases (in 2014 and 2018 respectively). DISCUSSION: Individuals in Centers for Social Inclusion are at risk of presenting STIs and co-infections; therefore, STI prevention campaigns and screenings should be conducted in this vulnerable group.


Subject(s)
Humans , Male , Sexually Transmitted Diseases/diagnosis , Sexually Transmitted Diseases/epidemiology , Venezuela/epidemiology , Enzyme-Linked Immunosorbent Assay , Biomarkers/analysis , Serotyping , HIV Infections/epidemiology , Epidemiology, Descriptive , Prevalence , Retrospective Studies , Hepatitis C/epidemiology , Vulnerable Populations , Coinfection , Hepatitis B/epidemiology
10.
Bol. méd. postgrado ; 35(2): 35-39, Jul.-Dec. 2019. graf
Article in Spanish | LILACS, LIVECS | ID: biblio-1120206

ABSTRACT

La infección por virus Zika es transmitida por la picadura del Aedes sp, aunque también se ha descrito la transmisión transplacentaria a los fetos. La microcefalia congénita es el primer hallazgo relacionado con la enfermedad y se asocia a defectos en la proliferación neuronal y muerte de las células progenitoras corticales que tiene como consecuencia una disminución de la producción neuronal y que resulta en una serie de trastornos cerebrales que comprometen la motricidad, visión, audición y funciones cognitivas. La presente investigación describió las características epidemiológicas, clínicas e imagenológicas en pacientes pediátricos con microcefalia secundario a la sospecha de infección por el virus Zika, que acudieron a la consulta de Neuropediatría del Servicio Desconcentrado Hospital Pediátrico Dr. Agustín Zubillaga de la ciudad de Barquisimeto, estado Lara durante el lapso diciembre 2016- septiembre 2017(AU)


Zika virus infection is transmitted by the bite of Aedes sp, although transplacental transmission to the fetuse has also been described. Congenital microcephaly is the first finding related to the disease and is associated with defects in neuronal proliferation and death of cortical progenitor cells, which result in a decrease in neuronal production and a group of brain disorders which compromise motor skills, vision, hearing and cognitive functions. The present study describes the epidemiological, clinical and imaging characteristics in pediatric patients with microcephaly secondary to suspected Zika virus infection who attended the Neuropediatric consultation of the Servicio Desconcentrado Hospital Pediátrico Dr. Agustín Zubillaga during the December 2016-September 2017 period(AU)


Subject(s)
Humans , Male , Female , Infant , Placental Circulation , Zika Virus/pathogenicity , Microcephaly/epidemiology , Microcephaly/diagnostic imaging , Venezuela/epidemiology , Tomography, X-Ray Computed , Reflex, Abnormal
11.
Rev. Inst. Nac. Hig ; 50(1-2): 30-37, Diciembre 2019. tab
Article in Spanish | LILACS, LIVECS | ID: biblio-1118387

ABSTRACT

Objetivo General: Determinar el riesgo de Tromboembolismo pulmonar (TEP) y Trombosis venosa profunda (TVP) en un grupo pacientes con patologías médicas. Métodos: Se realizó un estudio, unicéntrico, descriptivo, longitudinal, en pacientes > 18 años, ingresados por un periodo mayor de 72 horas en el servicio de medicina interna del Hospital Central del IVSS "Dr. Miguel Pérez Carreño", aplicando los modelos de evaluación de riesgos de Padua y Caprini. Resultados: La muestra estuvo representada por 114, el promedio de edad fue de 51 años ± 23, de mayoría femenino con 55 %, el principal diagnóstico de ingreso hospitalario, fue de origen infeccioso con 42,2 %. La escala Padua clasificó como bajo riesgo al 88,6 % y Caprini en alto riesgo al 36,8 %. El primer factor de riesgo fue la edad > 40 años con 82,46 %. El 3,51% de los pacientes presentaron un evento tromboembólico, teniendo positividad en el Dímero D con una media de 733,7 ± 181,3, al igual el eco-doppler venoso y en el caso de TEP, el angiotac pulmonar evidenció trombo de la rama derecha de la arteria pulmonar. Los dos factores de riesgo en este grupo estuvo dado por la edad (>65 años) y tasa de filtración glomerular <90 mL/min/1.73m2. El modelo de evaluación de riesgos de Padua presentó mayor capacidad predictiva (p < 0,05). Conclusión: La presencia de ETEV fue baja, a pesar que la muestra evaluada presentaba factores de riesgo y sin terapia trombo profiláctica, que evidencia la necesidad de evaluar los modelos de riesgos en pacientes con patologías médicas hospitalizados


General Objective: To determine the risk of pulmonary thromboembolism (PET) and deep vein thrombosis (DVT) in a group of patients with medical pathologies. Methods: A longitudinal, descriptive, single-center study was conducted in patients > 18 years, admitted for a period of more than 72 hours in the internal medicine service of the Central Hospital of the IVSS "Dr. Miguel Pérez Carreño", applying the Padua and Caprini risk assessment models. Results: The sample was represented by 114, the average age was 51 years ± 23, mostly female with 55 %, the main diagnosis of hospital admission, was of infectious origin with 42,2 %. The Padua scale classified 88,6 % as low risk and Caprini as high risk 36.8 %. The first risk factor was age > 40 years with 82,46 %. 3,51% of the patients presented a thromboembolic event, having a D-Dimer positivity with a mean of 733,7 ± 181,3, like venous echo-Doppler and, in the case of PET, pulmonary angiotac showed thrombus of the right branch of the pulmonary artery. The two risk factors for this group were given by age (> 65 years) and glomerular filtration rate <90 mL / min / 1.73m2. The Padua risk assessment model showed greater predictive capacity (p < 0.05). Conclusion: The presence of VTE was low, despite the fact that the sample evaluated presented risk factors and without thromboprophylactic therapy, which shows the need to evaluate the risk models in patients with hospitalized medical conditions


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Pulmonary Embolism/epidemiology , Venous Thrombosis/epidemiology , Hospitalization , Venezuela/epidemiology , Risk Factors , Longitudinal Studies
12.
Int. j. cardiovasc. sci. (Impr.) ; 31(6): 603-609, nov.- dez. 2018. tab, ilus
Article in English | LILACS | ID: biblio-979878

ABSTRACT

Background: No previous study has evaluated the prevalence of metabolic syndrome (MS) in more than one region in Venezuela.Objective: To determine the prevalence of MS in three Venezuelan regions. Methods: From 2006 to 2010, a total of 1,320 subjects aged ≥ 20 years were selected by multistage stratified random sampling from the regions of Lara State (western region), Mérida State (the Andean region), and Capital District (Capital Region). Anthropometric measurements, blood pressure, and biochemical analysis were obtained from each participant. MS was defined according to the harmonized Joint Interim Statement (2009) definition.Results: Mean age was 44.8 ± 0.39 years and 68.5% of the participants were female. The overall prevalence of MS was 35.7% (95% confidence interval 32.2 ­ 39.2%), while the prevalence was 42.5% (95% CI 38.8 ­ 46.1%) among men and 32.6% (95% CI 29.1 ­ 36.0%) among women (p < 0.001). In women, the prevalence of MS increased at almost every decade of life, while in men, the prevalence was similar from the age of 30 years onwards. The most prevalent abnormalities were low HDL-c levels (58.6%, 95% CI 54.9 ­ 62.1%), abdominal obesity (52.0%, 95% CI 48.4 ­ 55.7%), and elevated triglycerides levels (39.7%, 95% CI 36.1 ­ 43.2%). The prevalence of MS increased with increasing body mass index categories. Conclusion: In Venezuela, MS is a highly prevalent condition, which increases the risk of type 2 diabetes and cardiovascular disease in a large number of subjects


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Venezuela/epidemiology , Prevalence , Metabolic Syndrome/epidemiology , Blood Pressure , Cardiovascular Diseases , Sex Factors , Data Interpretation, Statistical , Risk Factors , Diabetes Mellitus , Dyslipidemias , Obesity, Abdominal , Observational Study , Hypercholesterolemia , Cholesterol, HDL
13.
Int. j. med. surg. sci. (Print) ; 5(2): 75-79, jun. 2018. tab
Article in English | LILACS | ID: biblio-1254394

ABSTRACT

Objective: To describe the clinical and sociodemographic characteristics of patients with temporomandibular joint ( TMJ) dysfunction at the University Hospital of Maracaibo. Methods: A retrospective study was conducted by assessing the clinical history of patients with TMJ dysfunction who underwent orthopedic treatment in the Oral Surgery Unit of the Dentistry Service of the University Hospital of Maracaibo. Information was collected on socio-demographic characteristics (age, gender, origin, and occupation) and clinical findings related to the presence, location, area, beginning, frequency, cause, and duration of pain, and signs present during mandibular dynamics; additionally, a structural and functional diagnosis was made. The data were processed and analyzed using SPSS v.9. Results: 221 patients were included, with only 10% of the disorders observed in males. Regarding occupation, 39.1% worked at home and 28.3% were students. 97.2% of patients presented pain, and of these, pain was localized in 75%. During mandibular movement with maximum opening, 47.4% showed some difficulty, which was more significant in males. TMJ noises were noted in 74.9%, more often in females. In addition, the previous partial displacement of a disk with recapture presented an incidence of 66.4%. Conclusion: The prevalence of TMJ dysfunction was higher in female patients and in adulthood. Noises were present with a high frequency, as was limited mandibular movement.


Subject(s)
Humans , Temporomandibular Joint Disorders/epidemiology , Venezuela/epidemiology , Prevalence , Retrospective Studies , Age and Sex Distribution
14.
Medisan ; 22(6)jun. 2018. tab
Article in Spanish | LILACS | ID: biblio-955044

ABSTRACT

Se realizó un estudio descriptivo, observacional, longitudinal y retrospectivo, de todos los pacientes notificados en los registros estadísticos de las comunidades de pobreza extrema y las nuevas urbanizaciones del estado Carabobo, durante el primer semestre del 2016, con vistas a identificar las actividades desarrolladas en estos, de acuerdo a las siguientes variables: consultas estomatológicas, actividades de promoción de salud, otros procedimientos estomatológicos y las remisiones al segundo nivel de atención. Entre los resultados se obtuvo que el mayor porcentaje de consultas se realizara en el primer trimestre del año, con predominio de las consultas-convenios, así como de las actividades de promoción de la salud. El grupo etario de menores de 18 años fue el más beneficiado con las actividades afectivo-participativas impartidas, en tanto los procedimientos estomatológicos preponderaron también en el primer trimestre, a excepción de la aplicación de laca de flúor, y la enfermedad periodontal fue la causa más frecuente de remisión al segundo nivel de atención


A descriptive, observational, longitudinal and retrospective study, from all the patients notified in the statistical records of extreme poverty communities and from the new urbanizations of the state Carabobo was carried out during the first semester of 2016, with the objective of describing the activities developed in them, according to the following variables: estomatological visits, health promotion activities, other estomatological activities and referral at the second care level. Among the results it was obtained that the highest percentage of visits was carried out in the first trimester of the year, with prevalence of the visits-agreements, as well as of the health promotion activities. The age group younger than 18 years had the greatest benefits with the delivered affective-participative activities, while the estomatological procedures also prevailed in the first trimester, except the use of fluorine, and the periodontal disease was the most frequent cause of referral to the second care level


Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Venezuela/epidemiology , Oral Health , Comprehensive Dental Care , Health Promotion , Poverty , Urbanization , Retrospective Studies , Longitudinal Studies
15.
Arq. bras. cardiol ; 110(1): 30-35, Jan. 2018. tab, graf
Article in English | LILACS | ID: biblio-887997

ABSTRACT

Abstract Background: The prevalence of dyslipidemia in multiple regions of Venezuela is unknown. The Venezuelan Metabolic Syndrome, Obesity and Lifestyle Study (VEMSOLS) was undertaken to evaluate cardiometabolic risk factors in Venezuela. Objective: To determine the prevalence of dyslipidemia in five populations from three regions of Venezuela. Methods: During the years 2006 to 2010, 1320 subjects aged 20 years or older were selected by multistage stratified random sampling from all households in five municipalities from 3 regions of Venezuela: Lara State (Western region), Merida State (Andean region), and Capital District (Capital region). Anthropometric measurements and biochemical analysis were obtained from each participant. Dyslipidemia was defined according to the NCEP/ATPIII definitions. Results: Mean age was 44.8 ± 0.39 years and 68.5% were females. The prevalence of lipids abnormalities related to the metabolic syndrome (low HDL-c [58.6%; 95% CI 54.9 - 62.1] and elevated triglycerides [39.7%; 36.1 - 43.2]) were the most prevalent lipid alterations, followed by atherogenic dyslipidemia (25.9%; 22.7 - 29.1), elevated LDL-c (23.3%; 20.2 - 26.4), hypercholesterolemia (22.2%; 19.2 - 25.2), and mix dyslipidemia (8.9%; 6.8 - 11.0). Dyslipidemia was more prevalent with increasing body mass index. Conclusion: Dyslipidemias are prevalent cardiometabolic risk factors in Venezuela. Among these, a higher prevalence of low HDL is a condition also consistently reported in Latin America.


Resumo Fundamento: A prevalência de dislipidemia em várias regiões da Venezuela é desconhecida. A Síndrome Metabólica venezuelana, Obesidade e Estilo de Vida Estudo (VEMSOLS) foram realizados para avaliar os fatores de risco cardiometabólico na Venezuela. Objetivo: Determinar a prevalência de dislipidemia em cinco populações de três regiões da Venezuela. Métodos: Durante os anos de 2006 a 2010, 1320 indivíduos com 20 anos ou mais foram selecionados por amostragem aleatória estratificada de vários estágios de todas as famílias em cinco municípios a partir de 3 regiões da Venezuela: Estado Lara (região Oeste), Estado de Mérida (região andina) e Capital Distrito (região Capital). medidas antropométricas e análise bioquímica foram obtidas de cada participante. Dislipidemia foi definida de acordo com as definições NCEP / ATPIII. Resultados: A idade média foi de 44,8 ± 0,39 anos, e 68,5% eram do sexo feminino. A prevalência de lípidos anormalidades relacionadas à síndrome metabólica (HDL-c baixo [58,6%; IC95% 54,9-62,1] e triglicerídeos elevados [39,7%; 36,1-43,2]) foram as alterações lipídicas mais prevalente, seguida pela dislipidemia aterogênica ( 25,9%; 22,7-29,1), LDL-C elevado (23,3%; 20,2-26,4), hipercolesterolêmica (22,2%; 19,2-25,2), e misturar dislipidemia (8,9%; 6,8-11,0). Dislipidemia foi mais prevalente com o aumento do índice de massa corporal. Conclusão: As dislipidemias são fatores de risco cardiometabólico prevalentes na Venezuela. Entre elas, uma maior prevalência de baixo HDL é uma condição também consistentemente relatada na América Latina.


Subject(s)
Humans , Male , Female , Adult , Dyslipidemias/epidemiology , Venezuela/epidemiology , Prevalence , Cross-Sectional Studies , Risk Factors , Spatial Analysis , Life Style
16.
Med. interna (Caracas) ; 34(4): 224-236, 2018. tab
Article in Spanish | LILACS, LIVECS | ID: biblio-1005878

ABSTRACT

Analizar las características clínicas y epidemiológicas de los pacientes que presentan insuficiencia cardíaca aguda. Métodos: Se realizó un estudio de casos, transversal, y descriptivo en 400 pacientes que cumplían con criterios de inclusión y con diagnóstico de insuficiencia cardíaca aguda atendidos en el servicio de Medicina Interna del Hospital General del Este Dr. Domingo Luciani, durante el periodo mayo 2016 ­ junio 2017. Resultados: 55 % de la población correspondía al género femenino con un promedio de edad de 64,96 años. La presencia de enfermedades subyacentes se registró en un 77%, la HTA como la más frecuente seguida de diabetes mellitus (28,3%). La principal causa de descompensación fue omisión de tratamiento (52,3%) seguido de etiología infecciosa (33%). Los síntomas más frecuentes fueron disnea (88 %) y edema (85%). El signo clínico más frecuente fueron crepitantes (94%) y Pulso venoso yugular >5cmH2O (73%). Las alteraciones electrocardiográficas más frecuentes fueron: anomalía auricular izquierda (36,25 %), hipertrofia del ventrículo izquierdo (43,1 %) y extrasístoles ventriculares (6,87 %) mientras que las alteraciones ecocardiográficas más frecuentes fueron fracción de eyección <40 % (77,5%) dilatación moderada de cavidades. La mortalidad en las primeras 24 horas fue 9,5% Conclusiones: Predominó el género femenino con edades reportadas en la literatura y la etiología más frecuente la HTA. Los estudios ecocardiográficos coinciden con los descritos en la literatura. La mortalidad a las 24 horas fue alta(AU)


Objectives: to analyze the clinical and epidemiological characteristics of patients with acute heart failure. Methods: this is a descriptive and transversal case study of 400 patients who had criteria for acute heart failure. They were hospitalized at the Hospital Dr. Domingo Luciani, Venezuela from may 2016 to june 2017. Results: 55% of patients were female gender, and the mean age was 64,96 years old. 77% of patients had concomitant illness; arterial hypertension was the most frequent illness followed by diabetes (28,3%). The mean reason for decompensation was medicament´s interruption(52,3%) and infections illness was registered in 33%. The most frequent symptoms were dyspnea (880%), limb edema (85%). The more prominent clinical signs were pulmonary rales (94%) and jugular venous pulse >5cmH2O (73%). Electrocardiographic findings were left atrial enlargement (36,25%), left ventricular hypertrophy (43,12%) and ventricular extrasystolia (6,87%). Echocardiographic findings were ejection fraction <40% (77,5%) and left cavities with moderate dilatation (36,58%).The first 24 hours mortality was 9,5%. Conclusions: Female gender was predominant with a mean age similar to previous studies; the more frequent etiology was arterial hypertension. Echocardiographic findings were similar to those described in the literature. Mortality in the first 24 hours was high(AU)


Subject(s)
Humans , Male , Female , Heart Failure/pathology , Heart Failure/epidemiology , Hypertension/physiopathology , Venezuela/epidemiology , Clinical Laboratory Techniques
17.
Med. interna (Caracas) ; 34(1): 30-31, 2018. tab
Article in Spanish | LILACS, LIVECS | ID: biblio-1007897

ABSTRACT

Ningún estudio ha evaluado la prevalencia nacional de factores de riesgo cardiometabólico en Venezuela. Objetivo: El EVESCAM (Estudio Venezolano de Salud Cardio-Metabólica) fue diseñado para evaluar la prevalencia de los factores de riesgo cardiometabólico en sujetos con ≥ 20 años de las 8 regiones del país. Métodos: Estudio transversal, fueron reclutados un total de 4,454 participantes entre julio de 2014 y febrero de 2017, usando un muestreo multi-etápico estratificado por conglomerados. Fueron evaluados 3,445 (tasa de respuesta 77,3%), con una pérdida de datos de sólo 0,7%, para una muestra final de 3,420 participantes. Los datos fueron recolectados en los hogares y en centros de campo de la comunidad por personal entrenado. Luego de firmar el consentimiento informado, se aplicaron cuestionarios (clínicos, demográficos, actividad física, nutricionales y psicológicos), medidas antropométricas (peso, altura y circunferencia abdominal), grasa corporal por bioimpedancia, fuerza de aprehensión de la mano, presión arterial, electrocardiograma y mediciones bioquímicas (Prueba de tolerancia a la glucosa oral y perfil lipídico(AU)


Subject(s)
Humans , Male , Female , Cardiovascular Diseases/complications , Cardiovascular Diseases/epidemiology , Metabolic Diseases/complications , Venezuela/epidemiology , Public Health , Internal Medicine
19.
Rev. argent. endocrinol. metab ; 54(4): 176-183, dic. 2017. graf, tab
Article in English | LILACS | ID: biblio-957985

ABSTRACT

Aim: Visceral obesity is one of the most intensely researched cardiometabolic risk factors in recent years; nonetheless, its accurate assessment remains a challenge in regions were socioeconomic conditions hinder the widespread use of diagnostic methods for this purpose, such as imaging tests. In this setting, Visceral Adiposity Index (VAI) may be a useful tool. Thus, the objective of this study was to determine the VAI cutoff in adult population from Maracaibo City, Venezuela. Methods: This is a descriptive, cross-sectional study with multi-staged sampling; 2026 subjects of both genders aged ≥18 years were selected from this database and had their VAI calculated. In order to determine VAI cutoffs, subsamples of metabolically healthy and sick individuals were determined, with 599 and 286 subjects, respectively. Gender-specific and general ROC curves were plotted in order to identify the most suitable cutoff according to sensitivity and specificity. Results: Median VAI in the selected sample was 1.67 (0.97-2.78). The optimal cutoff was determined to be 1.91, with 70.3% sensitivity, 70.3% specificity [AUC = 0.777 (0.745-0.808)]. No differences were found between genders. Analysis by age revealed VAI to have greater predictive power among subjects aged < 30 years (cutoff: 1.53), 78.6% sensitivity, 72.8% specificity [AUC = 0.797 (0.709-0.884)]. Conclusion: We suggest a VAI cutoff of 1.9 for define dysfunctional adiposity in our population, with age being an important factor in the epidemiologic behavior of this variable, particularly in younger individuals.


Objetivo: La obesidad central es uno de los factores de riesgo cardiometabólicos emergente más evaluado durante los últimos años, sin embargo, su medición de forma precisa resulta un reto en aquellas poblaciones cuyas condiciones económicas dificultan la realización de métodos diagnósticos complejos, como pruebas de imagen. Por ello el objetivo de este estudio es determinar el punto de corte del índice de adiposidad visceral (VAI) en sujetos adultos de la ciudad de Maracaibo, Venezuela. Métodos: Se seleccionó a 2.026 individuos de ambos sexos, mayores de 18 años, de la base de datos del Estudio de prevalencia de síndrome metabólico en la ciudad de Maracaibo, un estudio descriptivo, transversal, con muestreo multietápico. El VAI se calculó para cada sexo y para la estimación del punto corte se seleccionó a 599 sujetos sanos y 286 enfermos, realizándose curvas COR para identificar el mejor valor de acuerdo con la sensibilidad y la especificidad. Resultados: El promedio de VAI en la muestra seleccionada fue 1,67 (0,97-2,78). El punto de corte fue 1,91 (70,3% de sensibilidad y 70,3% de especificidad) con AUC = 0,777 (0,745-0,808), sin diferencias en el punto de corte según sexo. En el análisis por grupos etarios la mayor capacidad predictiva fue para el grupo < 30 años con AUC = 0,797 (0,709-0,884), con un punto de corte de 1,53 (78,6% de sensibilidad y 72,8% de especificidad). Conclusión: El punto de corte indicado para VAI en nuestra población es de 1,9; considerando la edad como un factor importante en su comportamiento, especialmente en los grupos más jóvenes.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Metabolic Syndrome/epidemiology , Obesity, Abdominal/complications , Venezuela/epidemiology , Cross-Sectional Studies/statistics & numerical data , Obesity, Abdominal/diagnosis
20.
Cad. Saúde Pública (Online) ; 33(10): e00050216, oct. 2017. tab, graf
Article in Spanish | LILACS | ID: biblio-952323

ABSTRACT

Resumen: El objetivo del presente estudio fue determinar la seroprevalencia de la infección por Trypanosoma cruzi en el estado Sucre (Venezuela) y su asociación con factores de riesgo epidemiológicos. El diseño muestral por conglomerados permitió seleccionar 96 centros poblados y 576 viviendas en los 15 municipios del estado. Asimismo, se evaluaron un total de 2.212 muestras de sueros, a través de las pruebas de ELISA, HAI e IFI. La seroprevalencia en el estado Sucre fue de 3,12%. Los factores de riesgo asociados a la infección por T. cruzi fueron: deposición de basura, materiales predominantes en el piso y paredes, tipo de vivienda, vivir en casas con paredes de bahareque y/o techos de palmas, vivir en casa con paredes y techos de riesgo, construcciones de riesgo y anexos de bahareque, aves dentro de la vivienda y la presencia de leña. La infección se encontró asociada a la edad de los individuos, se detectaron tres casos seropositivos en menores de 15 años. En el estado Sucre existen variables epidemiológicas que favorecen el riesgo a contraer la infección por T. cruzi.


Abstract: The current study aimed to determine the seroprevalence of Trypanosoma cruzi infection in Sucre State, Venezuela, and its association with epidemiological risk factors. The cluster sampling design allowed selecting 96 villages and 576 dwellings in the State's 15 municipalities. A total of 2,212 serum samples were analyzed by ELISA, HAI, and IFI. Seroprevalence in Sucre State was 3.12%. Risk factors associated with T. cruzi infection were: accumulated garbage, flooring and wall materials, type of dwelling, living in a house with wattle and daub walls and/or straw roofing, living in a house with risky walls and roofing, risky buildings and wattle and daub outbuildings, poultry inside the human dwelling, and presence of firewood. Infection was associated with individual age, and three seropositive cases were found in individuals less than 15 years of age. Sucre State has epidemiological factors that favor the risk of acquiring T. cruzi infection.


Resumo: O estudo teve como objetivo determinar a soroprevalência da infecção pelo Trypanosoma cruzi no Estado de Sucre, Venezuela, e a associação com fatores de risco epidemiológicos. O delineamento da amostragem em clusters permitiu a seleção de 96 vilarejos e 576 moradias nos 15 municípios do Estado. No total, 2.212 amostras de soro foram analisadas com ELISA, HAI e IFI. O estudo mostrou uma soroprevalência de 3,12% no Estado de Sucre. Os seguintes fatores de risco estiveram associados à infecção pelo T. cruzi: acúmulo de lixo, materiais de piso e paredes impróprios, tipo de moradia, moradias com paredes de pau-a-pique e/ou teto de palha, moradias em situação de risco e construções anexas feitas de pau-a-pique, aves dentro das moradias e presença de lenha. A infecção esteve associada à idade individual, e três casos soropositivos foram identificados em indivíduos com menos de 15 anos de idade. O Estado de Sucre apresenta fatores epidemiológicos que aumentam o risco de infecção pelo T. cruzi.


Subject(s)
Humans , Animals , Male , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Aged , Aged, 80 and over , Young Adult , Trypanosoma cruzi , Rural Health/statistics & numerical data , Chagas Disease/blood , Chagas Disease/epidemiology , Venezuela/epidemiology , Seroepidemiologic Studies , Residence Characteristics , Cross-Sectional Studies , Risk Factors , Chagas Disease/transmission , Middle Aged
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