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1.
Enferm. foco (Brasília) ; 11(2): 29-34, jul. 2020. graf, tab
Article in Portuguese | LILACS (Americas), BDENF | ID: biblio-1104006

ABSTRACT

Objetivo: descrever a prevalência dos tipos de feridas com indicação para oxigenoterapia hiperbárica. Método: estudo transversal, quantitativo e retrospectivo. Foram analisados prontuários de pacientes atendidos no setor de medicina hiperbárica referentes ao período de janeiro a dezembro de 2015. Empregou-se estatística descritiva e analítica. Resultados: Nos 60 prontuários analisados foram prevalentes: idade entre 19-49 anos e 61-72 anos (ambas com 27,1%), sexo masculino (68,3%), Diabetes Mellitus (44,1%) e deiscência cirúrgica (20,3%). Pessoas com idade de 61-72 anos tiveram maior tempo de sessões (mediana = 40 sessões). A regressão por modelagem linear utilizando como preditor a variável tempo de tratamento pela doença, demonstrou significância estatística do tabagismo e doença hematológica. Discussão: Os achados corroboram com estudos sobre a ocorrência de feridas. Conclusão: O estudo de prevalência poderá contribuir para a elaboração de um plano de cuidados de enfermagem individualizado ao portador de feridas que realizam tratamento no setor de oxigenoterapia hiperbárica. (AU)


Objective: Describe the prevalence of types of wounds indicated for hyperbaric oxygen therapy. Method: cross-sectional, quantitative and retrospective study. Were analyzed medical records of patients seen in the hyperbaric medicine sector for the period from January to December 2015. Descriptive and analytical statistics were used. Results: In the 60 medical records analyzed, the following were prevalent: age between 19-49 years and 61-72 years (both with 27,1%), male (68,3%), Diabetes Mellitus (44,1%) and surgical dehiscence (20,3%). People aged 61-72 years had longer sessions (median = 40 sessions). Regression by linear modeling using the variable duration of treatment for the disease as a predictor, demonstrated statistical significance of smoking and hematological disease. The findings corroborate with studies on the occurrence of wounds. Conclusion: The prevalence study may contribute to the development of an individualized nursing care plan for patients with wounds undergoing treatment in the hyperbaric oxygen therapy sector. (AU)


Objetivo: describir la prevalencia de los tipos de heridas indicadas para la oxigenoterapia hiperbárica. Método: estudio transversal, cuantitativo y retrospectivo. Se analizaron los registros médicos de pacientes atendidos en el sector de la medicina hiperbárica para el período de enero a diciembre de 2015. Se utilizaron estadísticas descriptivas y analíticas. Resultados: en los 60 registros médicos analizados, prevalecieron los siguientes: edad entre 19-49 años y 61-72 años (ambos con 27.1%), hombres (68.3%), diabetes mellitus (44.1%) y dehiscencia quirúrgica ( 20,3%). Las personas de 61 a 72 años tuvieron sesiones más largas (mediana = 40 sesiones). La regresión por modelado lineal utilizando la duración variable del tratamiento de la enfermedad como predictor, demostró la importancia estadística del tabaquismo y la enfermedad hematológica. Los hallazgos corroboran con los estudios sobre la aparición de heridas. Conclusión: El estudio de prevalencia puede contribuir al desarrollo de un plan de atención de enfermería individualizado para pacientes con heridas que reciben tratamiento en el sector de oxigenoterapia hiperbárica. (AU)


Subject(s)
Hyperbaric Oxygenation , Wound Healing , Wounds and Injuries , Prevalence , Nursing
2.
J. nurs. health ; 10(2): 20102008, mai.2020.
Article in Portuguese | LILACS (Americas), BDENF | ID: biblio-1104136

ABSTRACT

Objetivo: descrever a avaliação nutricional subjetiva global em pacientes com úlcera venosa acompanhados em Unidades de Saúde da Família. Método: pesquisa quantitativa, descritiva, com 30 pacientes de cinco unidades do distrito sanitário do Subúrbio Ferroviário, em Salvador, Bahia, que estiveram em atendimento de março a junho de 2019. Para realização do estudo, foi utilizada a técnica de amostra não probabilística por conveniência. Resultados: pela avaliação subjetiva global, os pacientes foram classificados como bem nutridos, porém percebe-se um percentual alto de obesidade, sendo necessária uma educação em saúde para que a escolha do alimento seja de acordo com o teor calórico. Conclusões: é de fundamental importância que o profissional de saúde ofereça um cuidado integral ao paciente com úlcera venosa, realizando intervenções precisas e evidenciando a atenção ao estado nutricional durante todo tratamento, uma vez que a nutrição pode reduzir o tempo de tratamento das lesões.(AU)


Objective: to describe the subjective global nutritional assessment of patients with venous ulcers attended at a Family Health Unit. Method: a quantitative, descriptive study with 30 patients from five family health units in the health district of Subúrbio Ferroviário, in Salvador, Bahia, who were in care from March to June 2019. To conduct the study, the non-probabilistic for convenience sample was used. Results: in accordance with the Subjective Global Assessment, the patients were classified as well nourished, however, a high percentage of obesity was observed, verifying the need for health education in order for the choice of food to be in accordance with its nutritional contents. Conclusions: it is of fundamental importance that the health professionals offer comprehensive care to patients with venous ulcers, performing precise interventions and evidencing attention to the nutritional status during the whole treatment, once nutrition can reduce the treatment time for the lesions.(AU)


Objetivo: describir la evaluación nutricional global subjetiva de pacientes con úlcera venosa asistidos en Unidades de Salud de la Familia. Método: investigación cuantitativa, descriptiva con 30 pacientes de cinco unidades en el distrito de salud de Subúrbio Ferroviário, en Salvador, Bahía, que estuvieron bajo cuidado de marzo a junio de 2019. La técnica de muestra fue no probabilística por conveniencia. Resultados: por la Evaluación Subjetiva Global los pacientes fueron clasificados en bien nutridos, pero se percibe un alto porcentaje de obesidad, verificando que es necesaria una educación en salud para que la elección del alimento sea de acuerdo con el contenido nutricional. Conclusiones: es de fundamental importancia que el profesional de saludo frezcaun cuidado integral al paciente con úlceras venosas, realizando intervenciones precisas y evidenciando la atención al estado nutricional durante todo el tratamiento, una vez que la nutrición puede reducir el tiempo de tratamiento de las lesiones.(AU)


Subject(s)
Varicose Ulcer , Wound Healing , Nutritional Status
3.
Int. j. morphol ; 38(2): 492-498, abr. 2020. graf
Article in Spanish | LILACS (Americas) | ID: biblio-1056467

ABSTRACT

Para promover la reparación y regeneración muscular, se han desarrollado diferentes estrategias, sin embargo, aún no existe un tratamiento único aceptado. Investigaciones relacionan los efectos terapéuticos de la miel en el proceso de cicatrización de heridas de diversas etiologías. Considerando lo anterior, el propósito de este estudio fue evaluar los efectos de una formulación basada en miel nativa (Ulmoplus®) en la reparación de lesiones musculares por incisión quirúrgica. A cinco conejos (Oryctolagus cuniculus) se les realizó una incisión de 20 mm de largo y 3 mm de ancho en la región anterior de cada pierna, atravesando la epidermis, dermis y el músculo tibial anterior, hasta alcanzar el periostio de la tibia. La pierna izquierda de cada animal fue clasificada como grupo sutura (S) y la derecha como grupo sutura más Ulmoplus® (S+U). Posteriormente, al grupo S+U se le aplicó Ulmoplus® en toda la extensión de la herida. Luego, en ambos grupos, la incisión fue suturada con cuatro puntos intradérmicos (vicryl 2/0). Un animal fue considerado como control para obtener imágenes histológicas del músculo tibial anterior sin injuria. A los 10 días post incisión, fueron tomadas las biopsias del músculo y posteriormente fueron procesadas para su observación en microscopio de luz. El estudio se llevó a cabo considerando las recomendaciones de la Guía para el Cuidado y Uso de Animales de Laboratorio. A los 10 días post incisión, las injurias, en ambos grupos de animales, se encontraban cerradas y sin signos de infección. El músculo tibial anterior de los especímenes del grupo S se encontraba en la fase de reparación, con procesos concomitantes de fagocitosis del tejido necrotizado, regeneración de miofibras y formación de tejido conectivo cicatrizal. El músculo tibial anterior de los animales del grupo S+U se encontraba en la fase de remodelación, ya que la arquitectura muscular se evidenciaba restablecida. Ulmoplus®, como coadyuvante en el proceso de cierre de heridas quirúrgicas de músculo esquelético utilizando sutura convencional, es una buena alternativa, ya que acelera el proceso de reparación muscular, y reduce el tejido conectivo cicatrizal.


To promote muscle repair and regeneration, different strategies have been developed, however, there is still no single accepted treatment. Research relates the therapeutic effects of honey in the wound healing process of various etiologies. The aim of this study was to evaluate the effects of native honey formulation (Ulmoplus®) in the repair of muscle injuries by surgical incision. In five rabbits (Oryctolagus cuniculus) were made an incision 20 mm long and 3 mm wide in the anterior region of each leg, crossing the epidermis, dermis and anterior tibial muscle, until reaching the tibia periosteum. The left leg of each animal was classified as a suture group (S) and the right leg as a suture group plus Ulmoplus® (S + U). Subsequently, Ulmoplus® was applied to the entire S + U group throughout the entire length of the wound. Then, in both groups, the incision was sutured with four intradermal points (vicryl 2/0). An animal was considered as a control to obtain histological images of the anterior tibial muscle without injury. At 10 days post incision, muscle biopsies were taken and subsequently processed for observation under light microscopy. The study was carried out considering the recommendations of the Guide for the Care and Use of Laboratory Animals. At 10 days post incision, the injuries, in both groups of animals, were closed and without signs of infection. The anterior tibial muscle of the S group specimens was in the repair phase, with concomitant processes of phagocytosis of the necrotized tissue, myofiber regeneration and formation of scar connective tissue. The anterior tibial muscle of the animals of the S + U group was in the remodeling phase, since the muscular architecture was evidenced restored. Ulmoplus®, as an adjunct in the process of closing surgical wounds of skeletal muscle using conventional suture, is a good alternative, since it accelerates the muscle repair process and reduces scar connective tissue.


Subject(s)
Animals , Rabbits , Wound Healing/drug effects , Surgical Wound/drug therapy , Honey , Muscles/injuries , Sutures , Disease Models, Animal
4.
Rev. Asoc. Odontol. Argent ; 108(1): 19-24, ene.-abr. 2020. ilus
Article in Spanish | LILACS (Americas) | ID: biblio-1096713

ABSTRACT

Objetivo: Presentar la terapia regenerativa como una al- ternativa para la resolución de un caso de traumatismo denta- rio en un diente permanente incompletamente desarrollado. Caso clínico: Se realizó el tratamiento de un incisivo central superior con mortificación pulpar y periodontitis api- cal aguda subsecuente a trauma dental en un paciente de 8 años de edad. Se aplicó el protocolo de regeneración pulpar recomendado por la Asociación Americana de Endodoncia. Se estimuló la formación de un coágulo en el interior del con- ducto a partir de los tejidos periapicales, previa desinfección con la pasta triple antibiótica, y finalmente se colocó mineral trióxido agregado coronal a este. Se obtuvo así una matriz es- teril que permitió el crecimiento de nuevo tejido y se realiza- ron controles periódicos durante 4 años. Se constató silencio clínico. Radiográficamente, se observó la formación de tejido sobre las paredes del conducto y el cierre apical. Conclusión: La terapia regenerativa como alternativa de tratamiento, en este caso, permitió la disminución de la luz del conducto por el depósito de tejidos calcificados y el cierre del foramen apical, mejorando el pronóstico de la pieza dentaria (AU)


Aim: To present pulp regeneration therapy as an alter- native to resolve dental trauma in immature permanent teeth. Clinical case: We report a clinical case of an immature central superior incisor with pulp mortification and acute api- cal periodontitis subsequent to dental trauma, in an 8 year old patient. The pulp Regeneration protocol recommended by the American Endodontics Association was applied. We stimulated a clot formation inside the duct from periapical tissues and after disinfection with a mixture of three antibi- otics mineral trioxide aggregated was finally place coronal to the clot. Thus a sterile matrix was obtained that allowed new tissue's growth. Periodic check-up visits were carried out over a 4 years period. Clinical silence was observed. Tissue formation on duct walls and apical closure were radiograph- ically detected (AU) Conclusion: Regenerative therapy is an alternative for the treatment of immature permanent teeth, in ths clinical case it allowed the reduction of the width of the duct by the opposition of hard tissues and the closure of the apical fora- men improving the forecast of these teeth.


Subject(s)
Regeneration , Dentition, Permanent , Incisor/injuries , Periapical Periodontitis , Argentina , Root Canal Filling Materials/therapeutic use , Wound Healing/physiology , Tooth Injuries/complications , Dental Pulp Necrosis , Tooth Apex/growth & development , Dental Service, Hospital
6.
Int. j. morphol ; 38(1): 186-192, Feb. 2020. graf
Article in English | LILACS (Americas) | ID: biblio-1056419

ABSTRACT

As a result of their intense physical activity, racehorses suffer high tendon stress which may result in various pathologies. One of these is tendonitis in the tendon of the superficial digital flexor muscle (TSDFM). Conventional treatment with rest, has not shown to be very effective, and regenerative medicine through the application mesenchymal stem cells appears to be a promising therapy. The objective of this work was to assess the effect of the application of autologous MSC on reduction of the scar length in recurrent TSDFM tendinitis in Holsteiner horses, using image analysis. This study included two groups of five animals each: A control group that received conventional treatment (CG) and an experimental group which was also treated with intralesional injections of MSC (EG). Scar evolution was assessed by echographic analysis, with measurements taken of the scar length over a four month period; the length at month zero, was taken as the initial value of 100 %. During the first month, the mean scar length diminished to 81.14 % (EG) and 95.85 % (CG); after the second month, lengths were 64.4 % (EG) and 92.3 % (CG); following the third month lengths were 51.92 % (EG) and 87.42 % (CG); finally at the end of the fourth month the lengths recorded were 26.7 % (EG) and 83.92 % (CG). These results show that treatment with autologous MSC helps TSDFM scar length was significantly reduced, as compared to conventional treatment.


Reducción de la cicatriz de tendinitis recidivante mediante células Madre mesenquimales autólogas derivadas de tejido adiposo de la base de la cola en equinos Holsteiner (Equus ferus caballus). En equinos deportistas, la actividad física intensa ocasiona gran estrés en los tendones, pudiendo ocasionar diversas patologías como la tendinitis del tendón del músculo flexor digital superficial (TMFDS). El tratamiento convencional con reposo es poco eficaz, siendo la medicina regenerativa a través de la aplicación de células madres mesenquimáticas (MSC) una promisoria terapia. El objetivo de este trabajo, fue evaluar el efecto de la aplicación de MSC autólogas, sobre la reducción de la longitud de la cicatriz en tendinopatías recidivantes del TMFDS en equinos Holsteiner, a través del análisis de imagen. Este estudio conto con dos grupos de cinco animales cada uno, el grupo control mantuvo el tratamiento convencional (GC) y el grupo experimental fue tratado adicionalmente con inyección interlesional de MSC (GE). El análisis ecográfico permitió evaluar la evolución de la cicatriz, a través de la medición de su longitud durante los cuatros meses, tomando la longitud del mes cero como la medición inicial del 100 %. Durante el primer mes, la longitud de la cicatriz se redujo a un 81,14 % (GE) y 95,85 % (GC), al segundo mes la longitud fue de un 64,4 % (GE) y de 92,3 % (GC), al tercer mes, la longitud fue de 51,92 (GE) y un 87,42 (GC), finalmente al cuarto mes la longitud fue de 26,7 % (GE) y del 83,92 % (GC). Estos resultados muestran que el tratamiento con MSC autólogas favorece a la disminución de la longitud de la cicatriz del TMFDS de forma significativa respecto al tratamiento convencional.


Subject(s)
Animals , Wound Healing , Adipose Tissue , Tendinopathy/therapy , Mesenchymal Stem Cells , Recurrence , Disease Models, Animal , Tendinopathy/complications , Horses
7.
Nursing (Säo Paulo) ; 23(264): 3966-3973, maio.2020.
Article in Portuguese | LILACS (Americas), BDENF | ID: biblio-1102665

ABSTRACT

A Síndrome de Fournier é um processo infeccioso severo que atinge os tecidos moles com avanço acelerado, possui etiologia polimicrobiana, com presença predominante de micro-organismos aeróbicos e anaeróbicos gram positivos e negativos. A finalidade deste trabalho é identificar por meio de revisão bibliográfica o conhecimento e atuação do enfermeiro sobre a síndrome de founier para que a sistematização de enfermagem seja executada de uma forma eficaz, prestando um atendimento eficiente ao paciente. Foi realizada revisão literária entre os anos de 2009 a 2019. Foram enfatizados a aplicabilidade da sistematização da assistência de enfermagem no tratamento, diagnóstico, complicações de acordo com a atuação do enfermeiro. Verificou-se que o tratamento incluiu a antibioticoterapia de amplo espectro e a cobertura mais indicada e utilizada foi à papaína. A oxigenoterapia hiperbárica foi aliada ao tratamento, porém questionada por alguns autores. Conclui- se que, de acordo com a revisão bibliográfica, não há dados publicados suficientes para realizar a análise.(AU)


Fournier syndrome is a severe infectious process that affects fast-advancing soft tissues, has a polymicrobial etiology, with predominant presence of aerobic and anaerobic gram positive and negative microorganisms. The purpose of this study is to identify through literature review the knowledge and performance of nurses about the Fournier syndrome so that nursing systematization is performed effectively, providing efficient care to the patient. A literature review was conducted between 2009 and 2019. The applicability of the systematization of nursing care in the treatment, diagnosis, and complications according to the nurse's performance was emphasized. The treatment was found to include broad spectrum antibiotic therapy and the most appropriate coverage used was papain. Hyperbaric oxygen therapy was combined with treatment but questioned by some authors. It is concluded that, according to the literature review, there are not enough published data to perform the analysis.(AU)


El síndrome de Fournier es un proceso infeccioso severo que afecta los tejidos blandos con un progreso acelerado, tiene una etiología polimicrobiana, con una presencia predominante de microorganismos gram positivos y negativos aerobios y anaerobios. El objetivo de este trabajo es identificar, mediante una revisión bibliográfica, el conocimiento y el desempeño de las enfermeras sobre el síndrome de Founier para que la sistematización de enfermería se realice de manera efectiva, brindando una atención eficiente al paciente. Se realizó una revisión literaria entre los años 2009 a 2019. Se enfatizó la aplicabilidad de la sistematización de la atención de enfermería en el tratamiento, diagnóstico, complicaciones según el desempeño de la enfermera. Se descubrió que el tratamiento incluía antibióticos de amplio espectro y la cobertura más indicada y utilizada fue la papaína. La oxigenoterapia hiperbárica se combinó con el tratamiento, pero algunos autores la cuestionaron. Se concluye que, según la revisión de la literatura, no hay suficientes datos publicados para realizar el análisis.(AU)


Subject(s)
Humans , Fournier Gangrene , Necrosis/prevention & control , Nursing Care/methods , Wound Healing , Wounds and Injuries/complications
8.
Fisioter. Mov. (Online) ; 33: e003318, 2020. tab, graf
Article in English | LILACS (Americas) | ID: biblio-1090390

ABSTRACT

Abstract Introduction: Photobiomodulation (PBM) assists in the processes of angiogenesis and cellular mitosis after skin lesion, contributing to tissue repair. Objective: to investigate the effects of photobiomodulation (during the proliferative phase) of 658 nm, 830 nm and 904 nm in the repair of skin lesions in an animal model. Method: 658 nm (G658), 830 nm (G830), 904 nm (G904) PBM, and control group (CG) integrated the research. We submitted the animals to an excisional wound and treatment at different wavelengths for 14 days. On the seventh and 14-1485004059th postoperative days, we calculated the area and percentage of lesion contraction. The animals were sacrificed on the 14-1485004056th postoperative day and cutaneous section of the injured region was collected for histomorphometric evaluation of the cellularity, neovascularization, thickness of the epidermis and volume density of collagen fibers colored with H&E and Picross Sirius respectively. For the statistical analysis, we applied the ANOVA test. Results: the G658 presented higher cellularity than GC (p = 0.03). The animals in the G658 group showed a significant increase in the neovascularization in relation to the CG (p = 0.01). Type III collagen significantly increased in G904 compared to G830 (p < 0.0001) and CG (p < 0.0001). The G658 had a significant increase in type III collagen fibers compared to G830 (p < 0.0001) and GC (p < 0.0001). We found no significant difference in the thickness of the epidermis, wound area, and in the percentage wound of contraction between the analyzed groups. Conclusion: PBM was effective to stimulate the tissue repair process, with better results for the 658 nm wavelength.


Resumo Introdução: A Fotobiomodulação (FBM) auxilia nos processos de angiogênese e mitose celular após lesão cutânea, contribuindo para reparo do tecido. Objetivo: investigar os efeitos da fotobiomodulação (durante a fase proliferativa) com comprimento de onda de 658 nm, 830 nm e 904 nm no reparo de lesões cutâneas em modelo animal. Método: FBM 658 nm (G658), 830 nm (G830), 904 nm (G904) e controle (GC) integraram a pesquisa. Os animais foram submetidos a uma ferida excisional e receberam tratamento em diferentes comprimentos de por 14 dias. No 7º e 14º dia pós-operatório, calculou-se a área e a porcentagem de contração da lesão. Os animais foram sacrificados no 14º dia pós-operatório e a secção cutânea da região lesada foi coletada para avaliação histomorfométrica da celularidade, neovascularização, espessura da epiderme e densidade volumétrica das fibras colágenas, corados com H&E e Picross Sirius respectivamente. Para a análise estatística, foi aplicado o teste ANOVA. Resultados: o G658 apresentou maior celularidade que GC (p = 0,03). Os animais do grupo G658 apresentaram aumento significativo da neovascularização em relação ao GC (p = 0,01). Houve aumento significativo do colágeno tipo III no G904 em relação ao G830 (p < 0,0001) e GC (p < 0,0001). O G658 teve um aumento significativo nas fibras colágenas tipo III em comparação ao G830 (p < 0,0001) e GC (p < 0,0001). Nenhuma diferença significativa foi encontrada na espessura da epiderme, área da ferida e na porcentagem de contração da ferida entre os grupos analisados. Conclusão: a PBM foi efetiva para estimular o processo de reparo tecidual, com melhores resultados para o comprimento de onda de 658 nm.


Resumen Introducción: La fotobiomodulación (FBM) auxilia en los procesos de angiogénesis y mitosa celular después de lesión cutánea, contribuyendo para la reparación. Objetivo: investigar los efectos de la fotobiomodulación (durante la fase proliferativa) con longitud de onda de 658 nm, 830 nm y 904 nm en la reparación de lesiones cutáneas en modelo animal. Método: grupos de FBM 658 nm (G658), 830 nm (G830), 904 nm (G904) y control (GC) integraron la investigación. Los animales fueron sometidos a una herida excisional y recibieron tratamiento 14 días. En el 7º y 14º día postoperatorio, se calculó el área y el porcentaje de contracción de la lesión. Los animales fueron sacrificados en el 14º día postoperatorio y la sección cutánea de la región lesada fue recolectada para evaluación histomorfométrica de la celularidad, neovascularización, espesor de la epidermis y densidad volumétrica de las fibras colágenas, colorados con H & E y Picross Sirius respectivamente. Para el análisis estadístico, se aplicó la prueba ANOVA. Resultados: G658 presentó mayor celularidad que GC (p = 0,03). G658 presentaron un aumento significativo de la neovascularización en relación al GC (p = 0,01). Se observó un aumento significativo del colágeno tipo III en el G904 con respecto al G830 (p < 0,0001) y GC (p < 0,0001). El G658 tuvo un aumento significativo en las fibras colágenas tipo III en comparación con el G830 (p < 0,0001) y GC (p < 0,0001). Ninguna diferencia significativa se encontró en el espesor de la epidermis, área de la herida entre los grupos. Conclusión: la PBM fue efectiva para estimular el proceso de reparación del tejido, con mejores resultados para grupo 658 nm.


Subject(s)
Animals , Low-Level Light Therapy , Wound Healing , Models, Animal
9.
Article in English, Portuguese | LILACS (Americas), BDENF | ID: biblio-1051356

ABSTRACT

Objetivo: Avaliar a evolução da cicatrização de úlceras nos membros inferiores de pacientes em uso de bota de Unna associada ao shiatsu. Método: Estudo de caso realizado na Policlínica Regional no interior de Minas Gerais com sete indivíduos portadores de úlceras nos membros inferiores. A coleta de dados foi realizada durante o tratamento associado a terapia alternativa/complementar shiatsu. Os dados foram analisados por estatística descritiva. Resultados: A média de idade foi de 61,5 anos, dentre as patologias de base, seis tinham diabetes mellitus, quatro eram hipertensos. Na avaliação dos membros inferiores, observou-se: área média inicial da ferida: 73 cm2 área média final 24 cm2 . PUSH inicial 14,8 e final 8,8. Dor inicial 2,7 e final 0,14. Conclusão: Percebeu-se redução na área das feridas, na intensidade da dor, e no número de feridas, indicando que o tratamento convencional associado a terapia alternativa complementar pode ser benéfico


Objective: To evaluate the evolution of healing ulcers in the lower limbs of patients using Unna boot associated with shiatsu. Method: A case study carried out in the Regional Polyclinic in the interior of Minas Gerais, Brazil, with seven individuals with ulcers in the lower limbs. Data collection was performed during treatment associated with alternative/complementary shiatsu therapy. Data were analyzed by descriptive statistics. Results: The mean age was 61.5 years, among the underlying pathologies, six had diabetes mellitus, four were hypertensive. In the evaluation of the lower limbs, we observed: initial mean wound area: 73 cm2 final mean area 24 cm2 . Initial PUSH 14.8 and final 8.8. Initial pain 2.7 and final 0.14. Conclusion: Reduction in wound area, pain intensity, and number of wounds was observed, indicating that conventional treatment associated with complementary alternative therapy may be beneficial


Objetivo: Evaluar la evolución de la cicatrización de úlceras en los miembros inferiores de pacientes en uso de bota de Unna asociada al shiatsu. Método: Estudio de caso realizado en la Policlínica Regional en el interior de Minas Gerais con siete individuos portadores de úlceras en los miembros inferiores. La recolección de datos fue realizada durante el tratamiento asociado a shiatsu. Los datos fueron analizados por estadística descriptiva. Resultados: El promedio de edad fue de 61,5 años, entre las patologías de base, seis tenían diabetes mellitus, cuatro eran hipertensos. En la evaluación de los miembros inferiores, se observó: área media inicial de la herida: 73 cm2 área media final 24 cm2 . PUSH inicial 14,8 y final 8,8. Dolor inicial 2,7 y final 0,14. Conclusión: Se percibió reducción en el área de las heridas, en la intensidad del dolor, y en el número de heridas, indicando que el tratamiento convencional asociado a terapia alternativa complementaria puede ser benéfico


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Diabetic Foot/therapy , Acupressure/methods , Compression Bandages , Varicose Ulcer/therapy , Wound Healing , Complementary Therapies , Risk Factors
10.
Article in English | WPRIM (Western Pacific) | ID: wprim-811272

ABSTRACT

OBJECTIVES: The need for proper wound closure is of paramount importance after any intra-oral surgery. Various wound closure techniques have been described in literature using traditional non-absorbable suture materials. These include like synthetic absorbable sutures, surgical staples and tissue adhesives. Cyanoacrylates are among the most commonly used biocompatible tissue adhesives. To evaluate and compare intraoral wound healing using 3-0 silk sutures and n-butyl-2-cyanoacrylate after alveoloplasty.MATERIALS AND METHODS: A total of 20 patients requiring bilateral alveoloplasty in the same arch (upper or lower) were included in this study. Patients with any pre-existing pathology or systemic disease were excluded. After alveoloplasty was performed, the wound was closed using 3-0 braided silk sutures on one side, and using n-butyl-2-cyanoacrylate bio adhesive on the other side. Patients were evaluated based on the following parameters: time required to achieve wound closure; the incidence of immediate and postoperative hemostasis; the time to the use of the first rescue medication; the side where pain first arises; and the side where wound healing begins first.RESULTS: Compared to 3-0 silk sutures, cyanoacrylate demonstrated better hemostatic properties, reduced operative time, reduced postoperative pain and better wound healing.CONCLUSION: These data suggest that cyanoacrylate glue is an adequate alternative to conventional sutures to close the surgical wound after alveoloplasty, and better than are 3-0 silk sutures.


Subject(s)
Adhesives , Alveoloplasty , Cyanoacrylates , Enbucrilate , Hemostasis , Humans , Incidence , Operative Time , Pain, Postoperative , Pathology , Silk , Sutures , Tissue Adhesives , Wound Closure Techniques , Wound Healing , Wounds and Injuries
11.
Article in English | WPRIM (Western Pacific) | ID: wprim-811113

ABSTRACT

BACKGROUND: Platelet-rich plasma (PRP) is a plasma component of autologous blood containing a high concentration of platelets. PRP is used to promote healing of damaged tissues. However, there are not many studies on the composition and expression patterns of active proteins in PRP. The purpose of this study was to identify unknown factors that contribute to tissue healing by proteomic analysis of proteins in PRP.METHODS: Three men in their 30s with no basal disease participated in this study. All identified proteins were classified for tissue healing-related functions on the basis of the gene ontology analysis of adhesion molecule with Ig-like domain 2 (AmiGO2). PRP was prepared by using the ACP kit and GPS III kit.RESULTS: We identified a total of 125 proteins related to wound healing, along with three proteins for angiogenesis involved in wound healing, two proteins for fibroblast migration, four proteins for collagen biosynthesis process, two proteins for glycosaminoglycan biosynthesis process, and 13 proteins for glycosaminoglycan binding. So, in addition to the growth factors that have been already known to be involved in tissue healing, 25 new proteins were identified.CONCLUSIONS: We identified the unknown proteins associated with tissue healing in PRP. Our findings may serve as a foundation for the establishment of basic medical evidence for PRP applications.


Subject(s)
Classification , Collagen , Fibroblasts , Gene Ontology , Humans , Intercellular Signaling Peptides and Proteins , Male , Plasma , Platelet-Rich Plasma , Proteome , Wound Healing
12.
Article in English | WPRIM (Western Pacific) | ID: wprim-811429

ABSTRACT

OBJECTIVES: This study aimed to evaluate the cell viability and migration of Endosequence Bioceramic Root Canal Sealer (BC Sealer) compared to MTA Fillapex and AH Plus.MATERIALS AND METHODS: BC Sealer, MTA Fillapex, and AH Plus were placed in contact with culture medium to obtain sealers extracts in dilution 1:1, 1:2 and 1:4. 3T3 cells were plated and exposed to the extracts. Cell viability and migration were assessed by 3-(4,5-dimethyl-thiazoyl)-2,5-diphenyl-tetrazolium bromide (MTT) and Scratch assay, respectively. Data were analyzed by Kruskal-Wallis and Dunn's test (p < 0.05).RESULTS: The MTT assay revealed greater cytotoxicity for AH Plus and MTA Fillapex at 1:1 dilution when compared to control (p < 0.05). At 1:2 and 1:4 dilutions, all sealers were similar to control (p > 0.05) and MTA Fillapex was more cytotoxic than BC Sealer (p < 0.05). Scratch assay demonstrated the continuous closure of the wound according to time. At 30 hours, the control group presented closure of the wound (p < 0.05). At 36 hours, only BC Sealer presented the closure when compared to AH Plus and MTA Fillapex (p < 0.05). At 42 hours, AH Plus and MTA Fillapex showed a wound healing (p > 0.05).CONCLUSIONS: All tested sealers demonstrated cell viability highlighting BC Sealer, which showed increased cell migration capacity suggesting that this sealer may achieve better tissue repair when compared to other tested sealers.


Subject(s)
3T3 Cells , Animals , Calcium , Cell Movement , Cell Proliferation , Cell Survival , Dental Pulp Cavity , Endodontics , Fibroblasts , Mice , Pemetrexed , Wound Healing , Wounds and Injuries
13.
Article in Korean | WPRIM (Western Pacific) | ID: wprim-811297

ABSTRACT

Interstitial lung disease (ILD) is a rare condition characterized by extensive inflammation and fibrosis mainly involving the pulmonary interstitium or alveoli. Usually, patients with ILD clinically present with chronic cough and exertional dyspnea. ILD is classified into subtypes based on clinical characteristics, detailed history obtained from patients, and radiological, and/or histopathological features. The most common type of idiopathic interstitial pneumonia is idiopathic pulmonary fibrosis (IPF). IPF is a chronic progressive fibrosing ILD and is associated with poor prognosis. An exclusive diagnosis of IPF requires no known condition causing ILD and typical radiological and/or histopathological features of lung fibrosis. Fibrosis observed in this condition is attributable to repetitive epithelial injury with consequent abnormal wound healing in genetically susceptible and elderly individuals. Currently, pirfenidone and nintedanib are useful disease-modifying agents available to treat IPF. In this article, we review the concept, diagnosis, clinical course, and treatment of ILD.


Subject(s)
Aged , Cough , Diagnosis , Dyspnea , Fibrosis , Humans , Idiopathic Interstitial Pneumonias , Idiopathic Pulmonary Fibrosis , Inflammation , Lung , Lung Diseases, Interstitial , Prognosis , Wound Healing
14.
Arq. ciências saúde UNIPAR ; 23(3): [197-212], set-dez. 2019.
Article in Portuguese | LILACS (Americas) | ID: biblio-1046184

ABSTRACT

Objetivou-se comparar a evolução da cicatrização de feridas cirúrgicas com cinco protocolos de tratamento através de análise planimétrica. Grupos de 12 ratos Wistar, foram alocados em cinco estudos experimentais: A- controle negativo; B- ferida cirúrgica, tratada com ultrassom terapêutico (UST) desligado ; C- ferida tratada somente com citrato de sildenafila ; D- ferida tratada com citrato de sildenafila e UST e grupo E-ferida tratada somente com UST. A evolução cicatricial foi acompanhada diariamente e avaliada por imagem fotográfica computadorizada aos sete, 14 e 21 dias. A aplicação do UST pulsado, com doses 1MHZ e 0,4Wcm2 reduziu o tempo de cicatrização epitelial em condições experimentais, favorecendo precocemente a reparação tecidual com efeitos qualitativos superiores ao tratamento com citrato de sildenafila (CS). A mensuração computacional para evolução da cicatrização de ferida dérmica mostrou-se um recurso de fácil aplicação sendo de baixo custo e eficiente para a aplicabilidade na rotina médica veterinária.


This study aimed at comparing the evolution of healing of surgical wounds with five treatment protocols through planimetric measurement. Groups of 12 Wistar rats were allocated in five experimental studies: A ­ negative control; B ­ surgical wound treated with therapeutic ultrasound turned off; C ­ surgical wound treated with sildenafil citrate; D ­ wound treated with sildenafil citrate and therapeutic ultrasound; and group E ­ wound treated only with therapeutic ultrasound. The healing progress was monitored daily and assessed by computed photographic image at seven, 14 and 21 days. It was concluded that the application of pulsated therapeutic ultrasound on surgical wounds at 1 MHz and 0.4Wcm2 doses reduces the epithelial healing time in experimental conditions, favoring the early repair of tissue with qualitative effects superior than the ones found in the treatment with sildenafil citrate (SC). The computational measurement for the evolution of the dermal wound healing proved to be an easy-to-apply resource, with a low cost and great efficiency for the applicability in the veterinary medical routine.


Subject(s)
Animals , Male , Rats , Wound Healing , Phonophoresis , Cicatrix/therapy , Phosphodiesterase 5 Inhibitors/therapeutic use , Sildenafil Citrate/therapeutic use , Skin/injuries , Time Factors , Ultrasonic Therapy , Rats, Wistar
15.
Int. j. morphol ; 37(4): 1234-1244, Dec. 2019. graf
Article in Spanish | LILACS (Americas) | ID: biblio-1040118

ABSTRACT

La cicatrización de la piel es un proceso complejo y organizado que involucra tres fases: inflamatoria, proliferativa y de remodelación. Es indispensable el análisis de este proceso biomolecularmente para investigar y proponer nuevas estrategias terapéuticas que mejoren la cicatrización o promuevan la regeneración. El objetivo de este proyecto fue analizar histológica y biomolecularmente mediante microespectroscopía infrarroja por transformada de Fourier (MFTIR) y su función de mapeo bioquímico, muestras de lesiones excisionales de piel, comparando los cambios morfológicos y espectroscópicos entre piel sana y piel cicatrizada. Se estandarizó un modelo de lesión excisional de piel en ratones hembra de la cepa NIH de 8 semanas de edad (n=16), provocando una herida excisional de 1 cm2. Se analizó piel sana (día 0) y cicatrizada (día 15 post-lesión) morfométrica, histológica y biomolecularmente mediante análisis fotográfico, técnica histológica y MFTIR con su función de mapeo. El análisis morfométrico demostró una reducción del área de la herida en un 87,6 % al día 15 post-lesión. Histológicamente, en la piel cicatrizada se evidenció un adelgazamiento de la epidermis y menor celularidad en la dermis, observándose la formación de tejido de granulación y fibras de colágena desorganizadas. Espectroscópicamente, se apreciaron cambios entre los dos grupos de estudio, principalmente en las bandas de lípidos y en la región de proteínas. El cálculo de las áreas bajo la curva y el mapeo bioquímico mostraron menor concentración de queratina y colágena en la piel cicatrizada, así como desorganización de las fibras de colágena. Se demostró la capacidad de la MFTIR para caracterizar de forma precisa los cambios biomoleculares en la cicatrización, entre ellos la cantidad de queratina, colágena, y el depósito y ordenamiento de las fibras de colágena asociadas a su maduración.


The skin cicatrization is a complex and organized process that involves three phases: inflammatory, proliferative, and remodeling. It is essential to analyze this process biomolecularly, in order to investigate and propose new therapeutic strategies that improve the healing or promote regeneration. The objective of this project was to analyze histological and biomolecularly through Fourier Transform infrared microspectroscopy (FTIRM) and its biochemical mapping function, samples of an excisional skin wound, comparing the morphological and spectroscopic changes between healthy skin and scarred skin. An excisional skin wound healing model was standardized using female, NIH strain 8-week-old mice (n = 16), provoking an excisional wound of 1 cm2. Healthy skin (day 0) and scarring skin (day 15 post-injury) were morphometrical, histological, and biomolecularly analyzed by digital picture analysis, histological technique, and FTIRM with its mapping function. The morphometric analysis showed a reduction of the wound area of 87.6 % at day 15 after wound. Histologically, in the scarred skin a thinning of the epidermis was evidenced, besides reduced cellularity in the dermis, granulation tissue formation, and disorganized collagen fibers were observed. Spectroscopically, changes between the study groups were appreciated, mainly in the lipid bands and in the protein region. The calculation of the areas under the curve and the biochemical mapping showed a lower concentration of keratin and collagen in the scarred skin, as well as collagen fibers disorganization. The ability of the FTIRM to accurately characterize biomolecular changes in cicatrization process was demonstrated, such as the amount of keratin, collagen, and the deposition and ordering of the collagen fibers associated with their maturation.


Subject(s)
Animals , Female , Mice , Skin/injuries , Wound Healing/physiology , Spectroscopy, Fourier Transform Infrared , Skin/pathology , Skin Physiological Phenomena , Disease Models, Animal
17.
Pesqui. vet. bras ; 39(10): 837-842, Oct. 2019. ilus
Article in English | LILACS (Americas), VETINDEX | ID: biblio-1056907

ABSTRACT

Chitosan has been successfully used as a biomaterial with several purposes in many species. In this study, chitosan membranes were produced with six different types of materials, and their behavior were evaluated upon implantation in the subcutaneous tissue of the flank of twelve healthy horses. We assessed chitosan membranes obtained from commercial chitosan, impregnated or not with silver nanoparticles, sterilized with ethylene oxide (CCEO, n=3; CCSNEO, n=3) or by ultraviolet radiation (CCUR, n=3; CCSNUR, n=3), and chitosan membranes obtained from squid gladius, sterilized with ethylene oxide (SCEO, n=6) or by ultraviolet radiation (SCUR, n=6). The same animals were randomly used in two experimental groups, with a minimum interval of 60 days between procedures, respecting the fact of only one flank side, left or right, be under evaluation by experimental period. After preparation of the membranes and implantation in the flank subcutaneous tissue of the horses, macroscopic and ultrasonographic evaluations of the implant regions were performed, as well as physical examination, blood count and fibrinogen measurement. No clinical or laboratory abnormalities were observed. All animals that received commercial chitosan membranes, regardless of the preparation technique, showed rejection to the biomaterials, considering that 100% of the surgical wounds presented dehiscence of suture and expulsion of the implants. The animals that received squid gladius chitosan membranes showed success in the treatment, with healing by primary intention of the surgical wound. We conclude that squid gladius chitosan membranes are biocompatible and biodegradable when implanted in the subcutaneous tissue of the flank of healthy horses.(AU)


A quitosana tem sido utilizada, com sucesso, como biomaterial para diversas espécies e finalidades. Neste estudo foi avaliada a confecção de membranas de quitosana, produzidas a partir de seis tipos de materiais diferentes e foi estudado seu comportamento quando implantadas no tecido subcutâneo do flanco de doze equinos sadios. Foram avaliadas membranas de quitosana obtidas de quitosana comercial, impregnadas ou não com nanopartículas de prata, esterilizadas com óxido de etileno (QCOE, n=3; QCNPOE, n=3) ou por radiação ultravioleta (QCRU, n=3; QCNPRU, n=3) e membranas de quitosana obtidas do gládio de lula, esterilizadas com óxido de etileno (GLOE, n=6) ou por radiação ultravioleta (GLRU, n=6). Os mesmos animais foram utilizados em dois grupos experimentais, de forma aleatória, com um intervalo mínimo de sessenta dias entre os procedimentos, respeitando-se o fato de apenas um lado do flanco, esquerdo ou direito, estar em avaliação por período experimental. Após preparo das membranas e implantação no tecido subcutâneo do flanco dos equinos, foram realizadas avaliações macroscópicas e ultrassonográficas das regiões de implante, além de exames físicos, hemogramas e fibrinogênio. Não foram observadas alterações clínicas e laboratoriais. Todos os animais que receberam membranas de quitosana comercial, independente da técnica de preparo, demonstraram rejeição dos biomateriais, uma vez que 100% das feridas cirúrgicas apresentaram deiscência da sutura e expulsão dos implantes. Os animais que receberam as membranas de quitosana de gladio de lula demonstraram sucesso no tratamento, com cicatrização das feridas cirúrgicas por primeira intenção. Conclui-se que membranas de quitosana de gládio de lula são biocompatíveis e biodegradáveis, quando implantadas no tecido subcutâneo do flanco de equinos sadios.(AU)


Subject(s)
Animals , Wound Healing , Chitosan/adverse effects , Chitosan/therapeutic use , Horses , Drug Implants
18.
Rev. Pesqui. (Univ. Fed. Estado Rio J., Online) ; 11(5): 1219-1225, out.-dez. 2019. tab
Article in English, Portuguese | LILACS (Americas), BDENF | ID: biblio-1022336

ABSTRACT

Objetivo: Avaliar os efeitos da irradiação ultrassônica de baixa frequência no tratamento de úlcera venosa. Método: Estudo de aplicação de tecnologia em saúde, realizado com indivíduos com lesões venosas, no ano de 2017 entre os meses de abril a agosto, utilizado formulário estruturado para coleta, analisados no programa Excel e representados em tabela e estatística descritiva. Resultados: Participaram cinco pacientes, três mulheres entre 65 e 88 anos de idade. Os participantes apresentaram cinco úlceras venosas, maioria localizada na porção inferior da perna. Houve redução mínima de 2,5% e máxima de 35,8% sobre a área das lesões. Um participante apresentou 100,0% de epitelização e os demais apresentaram tecido de granulação maior ou igual a 70,0%. Encontrou-se redução máxima de 10 pontos na PUSH, redução mínima de 2 pontos. Conclusão: A terapia ultrassônica traz aspectos positivos para o processo de reparação tecidual


Objective: The study's purpose has been to assess the effects of low-frequency ultrasound irradiation in the treatment of venous ulcer. Methods: It is a health technology application study, which was performed with individuals bearing venous lesions. The research was carried out over 2017 from April to August, using a structured form for data collection, where such data was analyzed in the Excel program and represented through tables and descriptive statistics. Results: Five patients have participated, being three women within the age group from 65 to 88 years old. The participants had five venous ulcers, predominantly located in the leg's lower portion. There was a reduction in the lesion area ranging from 2.5% (minimum) to 35.8% (maximum). One participant achieved 100% epithelization, and the others showed granulation tissue greater or equal to 70.0%. There was a maximum reduction of 10 points in the Pressure Ulcer Scale for Healing (PUSH), and a minimum reduction of 2 points. Conclusion: The low-frequency ultrasound therapy produces positive aspects to the tissue healing process


Objetivo: Evaluar los efectos de la irradiación ultrasónica de baja frecuencia en el tratamiento de úlcera venosa. Método: Estudio de aplicación de tecnología en salud, realizado con individuos con lesiones venosas, en el año 2017 entre los meses abril a agosto, utilizado formulario estructurado para recolección, analizados en el programa Excel y representados en tabla y estadística descriptiva. Resultados: Participaron cinco pacientes, tres mujeres entre 65 y 88 años de edad. Presentaron cinco úlceras venosas, mayoría localizada en la porción inferior de la pierna. Se observó una reducción mínima del 2,5% y una máxima del 35,8% sobre el área de las lesiones. Un participante presentó 100,0% de epitelización y los demás presentaron tejido de granulación mayor o igual al 70,0%. Se encontró reducción máxima de 10 puntos en la PUSH, reducción mínima de 2 puntos. Conclusión: La terapia ultrasónica trae aspectos positivos para el proceso de reparación del tejido


Subject(s)
Humans , Male , Female , Aged , Aged, 80 and over , Ultrasonic Therapy/nursing , Varicose Ulcer/therapy , Wound Healing , Wounds and Injuries/nursing , Wounds and Injuries/therapy , Biomedical Technology/methods
19.
Rev. bras. cir. plást ; 34(3): 399-404, jul.-sep. 2019. tab
Article in English, Portuguese | LILACS (Americas) | ID: biblio-1047163

ABSTRACT

Introdução: A Úlcera de Marjolin é definida como a malignização de cicatrizes, geralmente, crônicas, decorrentes de diversos tipos de lesão, sendo mais comum lesões por queimaduras. Métodos: Foi realizado levantamento bibliográfico nas plataformas BVS, PubMed, SciELO e Cochrane, tendo como critério de inclusão estudos publicados nos últimos 5 anos, que envolvem a espécie humana, disponíveis na web nos idiomas inglês ou português. Resultados: Analisados um total de 31, dos quais apenas 6 compuseram a amostra final. Discussão: As úlceras de Marjolin são encontradas em cicatrizes antigas de queimaduras, podem ocorrer em qualquer local, sendo mais comuns em membros superiores e inferiores. O diagnóstico inicia-se com a suspeita clínica baseada em características das lesões: lesões ulcerativas crônicas que não cicatrizam, com bordas elevadas e endurecidas e odor desagradável, podendo apresentar descarga purulenta. Esse só pode ser efetivado, entretanto, por meio do histopatológico da lesão. O período de latência entre a injúria da lesão e a sua malignização é, em média, de 30 a 35 anos. O tratamento deve ser individualizado, uma vez que depende de diversos fatores. Contudo, considera-se o padrão ouro a excisão cirúrgica. Conclusão: O conhecimento dos profissionais de saúde acerca dessa condição faz-se imprescindível para o melhor prognóstico do paciente. De modo que possíveis casos de malignização não tenham o seu diagnóstico subestimado, permita a terapêutica adequada à minimização das recidivas, e medidas profiláticas sejam efetivadas, no que tange à prevenção da queimadura e à minoração de fatores de risco para a malignização.


Introduction: Marjolin's ulcer is defined as a malignancy within scars that is usually chronic and results from several lesion types, with burn injuries being the most common. Methods: A bibliographic survey was conducted of the Virtual Health Library, PubMed, Scientific Electronic Library Online, and Cochrane databases using the inclusion criteria of studies published in the last 5 years, human studies, and published in English or Portuguese. Results: A total of 31 studies were analyzed, of which only 6 were included in the final sample. Discussion: Marjolin's ulcer is found in old burn scars and can occur anywhere, but it is more common in the upper and lower limbs. The diagnosis begins with the clinical suspicion based on lesion characteristics: chronic unhealed ulcerative lesions with high and hardened edges, an unpleasant odor, and purulent discharge. However, the diagnosis can only be made histopathologically. The latency period between injury and malignancy is 30­35 years. Although treatment should be individualized since it depends on several factors, surgical excision is considered the gold standard. Conclusion: Knowledge about this condition is essential to better patient prognosis and prevent underestimation of possible cases of malignancy, allowing for appropriate therapy to minimize recurrence and enabling prophylactic measures to prevent burn injury and reduce risk factors for malignancy.


Subject(s)
Humans , Female , Adult , History, 21st Century , Skin Ulcer , Surgery, Plastic , Wound Healing , Burns , Burns, Electric , Carcinoma , Skin Ulcer/surgery , Surgery, Plastic/adverse effects , Surgery, Plastic/methods , Burns/surgery , Burns/complications , Carcinoma/surgery , Carcinoma/complications
20.
Rev. bras. cir. plást ; 34(3): 384-390, jul.-sep. 2019. ilus, tab
Article in English, Portuguese | LILACS (Americas) | ID: biblio-1047160

ABSTRACT

Introdução: O tratamento de grandes e médias feridas é um desafio para os cirurgiões quando precisam fechálas e, normalmente, são utilizadas técnicas cirúrgicas de enxertias ou retalhos, que podem deixar sequelas e até mesmo mutilações. Ao longo do tempo desenvolveu-se a técnica de "sutura elástica" que promove a cicatrização em curto espaço de tempo com sequelas menores, entretanto o procedimento tem sido realizado com material improvisado. Objetivo: Desenvolver um fio de sutura elástico cirúrgico que possa ser esterilizado e confeccionado nos moldes dos produtos médicos cirúrgicos. Métodos: Revisão das patentes existentes por meio da busca de anterioridade e comparação com o dispositivo do estudo. Pesquisa de materiais com as características necessárias como elasticidade e tensão. Teste destas características em laboratórios especializados. Resultados: O produto desenvolvido é um fio elástico com duplo agulhamento para suturas, com matéria prima de silicone que apresenta elasticidade e resistência a tensão. Conclusão: O fio de sutura elástico, com duplo agulhamento, para feridas de médio e grande porte foi desenvolvido.


Introduction: Closing large and medium wounds is challenging for surgeons and often leads to the use of graft or flap surgical techniques. These procedures can leave sequelae and even mutilations. An "elastic suture" technique was developed to promote wound healing in a short time span with minor sequelae; however, improvised materials have been used in this procedure. Objective: To develop a surgical elastic suture thread that can be manufactured and sterilized following the standards of surgical medical products. Methods: We conducted a patent search, compared the findings with the study device, and researched materials with necessary characteristics such as elasticity and tension. Testing these characteristics in specialized laboratories. Results: The developed device is a double-needled elastic suture made of silicone that presents tensile strength. Conclusion: Here, we developed a double-needled elastic suture for medium and large wounds.


Subject(s)
Humans , History, 21st Century , Surgery, Plastic , Surgical Instruments , Sutures/standards , Wound Healing , Suture Techniques/instrumentation , Wound Closure Techniques , Surgery, Plastic/instrumentation , Surgery, Plastic/methods , Surgical Instruments/standards , Sutures , Wound Healing/ethics , Wounds and Injuries , Wound Closure Techniques/instrumentation
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