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1.
Goiânia; SES-GO; 26 out. 2020. 1-5 p. tab, graf.
Non-conventional in Portuguese | LILACS, ColecionaSUS, CONASS, SES-GO | ID: biblio-1141389

ABSTRACT

A febre amarela é uma doença febril aguda de curta duração (no máximo 12 dias) e de gravidade variável. Apesar da erradicação da febre amarela urbana no Brasil, a febre amarela silvestre é endêmica em nosso país devido à manutenção do vírus na natureza, pela transmissão entre primatas não humanos (PNH) e mosquitos silvestres arbóreos. Acidentalmente, seres humanos susceptíveis são infectados ao penetrar o ciclo enzoótico natural. Por isso é importante atenção aos "eventos sentinela", situações em que um número maior de PNH adoece e morre alertando a comunidade na forma de epizootia. Nessa situação definem-se estratégias de intensificação da vacinação nos moradores das regiões afetadas (BRASIL, 2018).


Yellow fever is a short-term acute febrile disease (maximum 12 days) and of varying severity. Despite the eradication of urban yellow fever in Brazil, wild yellow fever is endemic in our country due to the maintenance of the virus in nature, due to the transmission between non-human primates (NHP) and wild tree mosquitoes. Accidentally, susceptible humans are infected by penetrating the natural enzootic cycle. Therefore, it is important to pay attention to "sentinel events", situations in which a greater number of NHP gets sick and dies alerting the community in the form of epizootics. This situation defines strategies for intensifying vaccination in residents of the affected regions (BRASIL, 2018).


Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Aged , Aged, 80 and over , Yellow Fever/prevention & control , Yellow Fever/therapy
2.
Bol. latinoam. Caribe plantas med. aromát ; 19(1): 142-148, ene. 2020. ilus, tab
Article in English | LILACS | ID: biblio-1103091

ABSTRACT

The research of new substances capable of controlling the Aedes aegypti mosquito is urgent due to the increase in the transmission of the diseases such as dengue, chikungunya and Zika virus by the vector. Thus, the aim of this study was to evaluate the larvicidal activity of crude extract of Piper corcovadensis roots, a native plant from Brazil, and of the isolated compound piperovatine against larvae of A. aegypti by the larval immersion test. The lethal concentration that killed 50% (LC50) and 99% (LC99) of larvae was determined by Probit analysis. The results indicated high larvicidal activity on A. aegypti larvae for crude extract of Piper corcovadensis roots with LC50 of 4.86 µg/mL and LC99 of 15.50 µg/mL and piperovatine with LC50 of 17.78 µg/mL and LC99 of 48.55 µg/mL. This work opens new perspectives to the development of future products with crude extract of Piper corcovadensis roots and piperovatine that can be applied to mosquito control.


La investigación de nuevas sustancias capaces de controlar el mosquito Aedes aegypti es urgente debido al aumento en la transmisión de enfermedades como el dengue, el chikungunya y el virus Zika por el vector. Por lo tanto, el objetivo de este estudio fue evaluar la actividad larvicida del extracto crudo de las raíces de Piper corcovadensis, una planta nativa de Brasil, y del compuesto aislado piperovatine contra larvas de A. aegypti mediante la prueba de inmersión larvaria. La concentración letal que mató al 50% (LC50) y al 99% (LC99) de larvas se determinó mediante análisis Probit. Los resultados indicaron una alta actividad larvicida en larvas de A. aegypti para extracto crudo de las raíces de Piper corcovadensis con LC50 de 4.86 µg/mL y LC99 de 15.50 µg/mL y piperovatine con LC50 de 17.78 µg/mL y LC99 de 48.55 µg/mL. Este trabajo abre nuevas perspectivas para el desarrollo de futuros productos con extracto crudo de las raíces de Piper corcovadensis y piperovatine que pueden aplicarse al control de mosquitos.


Subject(s)
Animals , Sorbic Acid/analogs & derivatives , Plant Extracts/pharmacology , Aedes/drug effects , Piper/chemistry , Insecticides/pharmacology , Sorbic Acid/isolation & purification , Sorbic Acid/pharmacology , Yellow Fever/prevention & control , Brazil , Plant Roots , Dengue/prevention & control , Larvicides , Zika Virus Infection/prevention & control , Larva/drug effects , Methylene Chloride
3.
Mem. Inst. Oswaldo Cruz ; 115: e200284, 2020. tab, graf
Article in English | LILACS, SES-SP | ID: biblio-1135275

ABSTRACT

The coronavirus disease of 2019 (COVID-19) pandemic challenges public health systems around the world. Tropical countries will face complex epidemiological scenarios involving the simultaneous transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with viruses transmitted by Aedes aegypti. The occurrence of arboviral diseases with COVID-19 in the Latin America and the Caribbean (LAC) region presents challenges and opportunities for strengthening health services, surveillance and control programs. Financing of training, equipment and reconversion of hospital spaces will have a negative effect on already the limited resource directed to the health sector. The strengthening of the diagnostic infrastructure reappears as an opportunity for the national reference laboratories. Sharing of epidemiological information for the modeling of epidemiological scenarios allows collaboration between health, academic and scientific institutions. The fear of contagion by COVID-19 is constraining people with arboviral diseases to search for care which can lead to an increase in serious cases and could disrupt the operation of vector-control programs due to the reluctance of residents to open their doors to health personnel. Promoting intense community participation along with the incorporation of long lasting innovations in vector control offers new opportunities for control. The COVID-19 pandemic offers challenges and opportunities that must provoke positive behavioral changes and encourage more permanent self-care actions.


Subject(s)
Humans , Animals , Pneumonia, Viral/epidemiology , Yellow Fever/prevention & control , Coronavirus Infections/epidemiology , Coronavirus , Aedes/microbiology , Aedes/virology , Dengue/prevention & control , Pandemics , Americas , Caribbean Region , Mosquito Vectors , Betacoronavirus , SARS-CoV-2 , COVID-19
4.
Rev. bras. anal. clin ; 51(1): 25-28, 30/03/2019. tab
Article in Portuguese | LILACS | ID: biblio-1008146

ABSTRACT

A Febre Amarela é uma doença infecciosa aguda, caracterizada por febre. Não é transmissível e tem duração de no máximo 12 dias. As manifestações clínicas revelam as fases evolutivas da doença. Este trabalho consiste em um artigo de atualização, no qual foi realizado um estudo bibliográfico interpretativo e descritivo baseado na literatura atual sobre a Febre Amarela no Brasil. Esta doença é causada por um arbovírus que pertence à família Flaviviridae. A expansão da área de vacinação é muito discutida atualmente. Segundo o Ministério da Saúde, em 2016, foram confirmados seis casos de Febre Amarela no Brasil. Conforme a Sociedade Brasileira de Infectologia, a fisiopatologia desta doença é a mesma no ciclo urbano e no silvestre. O seu diagnóstico pode ser dividido em clínico e laboratorial, pois são as duas formas de confirmar a doença em indivíduos. As medidas preventivas consistem, principalmente, na imunização, medidas de proteção e no controle do vetor. Esta pesquisa fornece dados atuais em bases confiáveis, podendo ser utilizada para futuros trabalhos.


Yellow Fever is an acute infectious disease, characterized by fever. It is not transferable and lasts for a maximum of 12 days. The clinical manifestations reveal the evolutionary phases of the disease. This work consists of an update article, where an interpretative and descriptive bibliographic study was carried out based on the current literature on Yellow Fever in Brazil. This disease is caused by an arbovirus belonging to the family Flaviviridae. The expansion of the vaccination area is much discussed today. According to the Ministry of Health, in 2016, six cases of yellow fever were confirmed in Brazil. According to the Brazilian Society of Infectology, the pathophysiology of Yellow Fever is the same in the urban and wild cycle. The diagnosis of yellow fever can be divided into clinical and laboratory, as they are the two ways to confirm the disease in individuals. Preventive measures consist mainly of immunization, protective measures and vector control. This research provides current data on a reliable basis and can be used for future work


Subject(s)
Yellow Fever/diagnosis , Yellow Fever/etiology , Yellow Fever/epidemiology , Yellow Fever/physiopathology , Yellow Fever/prevention & control , Yellow Fever/therapy , Aedes
5.
Hist. ciênc. saúde-Manguinhos ; 26(1): 15-32, Jan.-Mar. 2019. tab, graf
Article in Portuguese | LILACS | ID: biblio-989872

ABSTRACT

Resumo A criação da Hospedaria de Imigrantes da Ilha das Flores, em 1883, esteve de acordo com os preceitos higienistas vigentes na época. O isolamento de imigrantes na costa leste da baía de Guanabara ocorreu em virtude das epidemias de febre amarela que retornavam à capital do Império todo verão, desde 1849-1850. Higienistas atribuíam a doença à precária condição sanitária da cidade do Rio de Janeiro, que propiciava a multiplicação do germe e infeccionava a atmosfera. Na medida em que os médicos reinterpretavam a doença à luz da teoria pasteuriana, foram sendo adotados novos procedimentos para a recepção de imigrantes, alterando a estrutura e o funcionamento da Hospedaria da Ilha das Flores.


Abstract The Hospedaria de Imigrantes (Immigrant Lodgings) da Ilha das Flores was established in 1883 in accordance with the hygienist thinking of the time. Immigrants were isolated on the east coast of Guanabara Bay because of the epidemics of yellow fever which returned to the Imperial capital every summer since 1849-1850. Hygienists attributed the disease to the precarious health conditions in the city of Rio de Janeiro, which enabled germs to multiply and infect the atmosphere. As physicians reinterpreted the disease in light of Pasteurian theory, new procedures were adopted to receive immigrants, changing the structure and function of the facility on Ilha das Flores.


Subject(s)
Humans , History, 19th Century , Yellow Fever/history , Public Health Practice/history , Hygiene/history , Emigrants and Immigrants/history , Hospitals, Special/history , Yellow Fever/prevention & control , Yellow Fever/epidemiology , Brazil/epidemiology , Facility Design and Construction/history , Epidemics/history
6.
Adv Rheumatol ; 59: 17, 2019. tab, graf
Article in English | LILACS | ID: biblio-1088607

ABSTRACT

Abstract Background: In Brazil, we are facing an alarming epidemic scenario of Yellow fever (YF), which is reaching the most populous areas of the country in unvaccinated people. Vaccination is the only effective tool to prevent YF. In special situations, such as patients with chronic immune-mediated inflammatory diseases (CIMID), undergoing immunosuppressive therapy, as a higher risk of severe adverse events may occur, assessment of the risk-benefit ratio of the yellow fever vaccine (YFV) should be performed on an individual level. Main body of the abstract: Faced with the scarcity of specific orientation on YFV for this special group of patients, the Brazilian Rheumatology Society (BRS) endorsed a project aiming the development of individualized YFV recommendations for patients with CIMID, guided by questions addressed by both medical professionals and patients, followed an internationally validated methodology (GIN-McMaster Guideline Development). Firstly, a systematic review was carried out and an expert panel formed to take part of the decision process, comprising BRS clinical practitioners, as well as individuals from the Brazilian Dermatology Society (BDS), Brazilian Inflammatory Bowel Diseases Study Group (GEDIIB), and specialists on infectious diseases and vaccination (from Tropical Medicine, Infectious Diseases and Immunizations National Societies); in addition, two representatives of patient groups were included as members of the panel. When the quality of the evidence was low or there was a lack of evidence to determine the recommendations, the decisions were based on the expert opinion panel and a Delphi approach was performed. A recommendation was accepted upon achieving ≥80% agreement among the panel, including the patient representatives. As a result, eight recommendations were developed regarding the safety of YFV in patients with CIMID, considering the immunosuppression degree conferred by the treatment used. It was not possible to establish recommendations on the effectiveness of YFV in these patients as there is no consistent evidence to support these recommendations. Conclusion: This paper approaches a real need, assessed by clinicians and patient care groups, to address specific questions on the management of YFV in patients with CIMID living or traveling to YF endemic areas, involving specialists from many areas together with patients, and might have global applicability, contributing to and supporting vaccination practices. We recommended a shared decision-making approach on taking or not the YFV.


Subject(s)
Humans , Yellow Fever/prevention & control , Chronic Disease , Yellow Fever Vaccine/administration & dosage , Brazil/epidemiology , Efficacy/standards , Treatment Outcome
10.
Rev. Asoc. Méd. Argent ; 131(3): 14-16, Sept. 2018.
Article in Spanish | LILACS | ID: biblio-1009230

ABSTRACT

Se describen la biología y la epidemiología de la fiebre amarilla (FA), haciendo referencia a la historia de la patología en Argentina y su situación en consonancia con los países vecinos de Brasil, Paraguay y Perú. Se describe su incidencia de los dos últimos años hasta la fecha en Brasil y Perú y su dispersión por infección humana a Chile y algunos países de Europa. Se recomienda para su prevención la implementación de mecanismos de vigilancia epidemiológica, que incluyan educación sanitaria, considerando que la toma de conciencia de la comunidad es trascendente para un adecuado control. (AU)


The biology and the epidemiology of yellow fever are described, with reference to the history of the disease in Argentina and its situation in line with the neighbouring countries of Brazil, Paraguay and Peru. It describes its incidence over the last two years to date in Brazil and Peru and its spread by human infection to Chile and some European countries. Epidemiological surveillance mechanisms are recommended for prevention, including heatlh education, considering that community awareness is important for adequate control. (AU)


Subject(s)
Humans , Animals , Yellow Fever/prevention & control , Yellow Fever/epidemiology , Health Education , Yellow Fever Vaccine , Epidemiological Monitoring , Paraguay , Peru , Argentina , Brazil , Chile , Public Health , Incidence , Europe
12.
Hist. ciênc. saúde-Manguinhos ; 25(1): 261-279, jan.-mar. 2018.
Article in Portuguese | LILACS | ID: biblio-892598

ABSTRACT

Resumo Em 1923, o doutor Sebastião Barroso, chefe do Serviço de Saneamento e Profilaxia Rural da Bahia, apresenta um relatório das atividades desenvolvidas no ano anterior. O documento reúne informações sobre as iniciativas coordenadas pela autoridade no tocante às epidemias e à profilaxia rural, acompanhadas de uma compilação dos relatórios dos profissionais responsáveis pelos postos de profilaxia rural e de tabelas contendo dados sobre os trabalhos nas diferentes regiões do estado, as notificações recebidas e as despesas realizadas. O trecho desse documento aqui apresentado permite uma aproximação das discussões em relação ao papel do Estado no enfrentamento dos problemas de saúde pública, num contexto marcado pela recorrente eclosão de surtos epidêmicos, dentre os quais se destacam os surtos de febre amarela.


Abstract In 1923, Doctor Sebastião Barroso, head of the Rural Sanitation and Prophylaxis Service of Bahia, submitted a report on the previous year's activities. The document contains information on initiatives coordinated by the entity on rural epidemics and prophylaxis, accompanied by a compilation of the reports by the professionals responsible for the rural prophylaxis units and tables containing data on the different regions in the state, notifications received, and expenses. The section of this document presented here enables us to investigate the state's role in addressing public health issues in a context marked by recurring outbreaks of epidemics, especially yellow fever.


Subject(s)
Humans , History, 20th Century , Public Health Administration/history , Yellow Fever/history , Public Health Practice/history , Sanitation/history , Yellow Fever/prevention & control , Yellow Fever/epidemiology , Brazil/epidemiology , Disease Outbreaks/history , Disease Outbreaks/prevention & control
13.
RECIIS (Online) ; 12(1): 1-5, jan.-mar. 2018.
Article in Portuguese | LILACS | ID: biblio-884962

ABSTRACT

Esta nota apresenta um breve histórico da origem da febre amarela no Brasil, das medidas de controle e das dificuldades para que orientações de saúde pública cheguem à população. Nela analisam-se alguns episódios de geração de boatos, assim como informações mentirosas e suas consequências muitas vezes danosas.Aponta-se a necessidade de oferecer e divulgar fontes confiáveis para os profissionais e a comunidade, em especial por meio do fortalecimento das instituições e de suas áreas de comunicação social. Assinala-se também a importância do trabalho de campo das equipes de atenção básica, para localizar pessoas expostas a risco, levando-lhes informações e vacinas.(AU)


This paper presents a brief history of yellow fever origin in Brazil, of the control measures and of the difficulties to the public health guidance to reach the population. It analyzes some cases of rumour propagation, as wellas fake information and its often damaging consequences. It points out the need to offer and disseminatereliable sources to professionals and the community, especially through the strengthening of institutions and their areas of social communication. It also highlights the importance of the fieldwork of the primary health care teams, so that they can find people at risk and bring information and vaccines to them.


Esta nota presenta una breve historia del origen de la fiebre amarilla en Brasil, de las medidas de control yde las dificultades de las orientaciones de salud pública para llegar a la población. Analiza algunos casos degeneración de rumores, así como informaciones falsas y sus consecuencias a menudo perjudiciales. Señalala necesidad de ofrecer y difundir fuentes confiables a los profesionales y a la comunidad, en especial a través del fortalecimiento de las instituciones y sus áreas de comunicación social. También destaca la importancia del trabajo de campo de los equipos de atención primaria de salud, para localizar personas expuestas alriesgo y así llevar a ellas informaciones y vacunas.


Subject(s)
Humans , Animals , Fraud/trends , Persuasive Communication , Yellow Fever/epidemiology , Yellow Fever/history , Brazil , Disease Outbreaks , Health Knowledge, Attitudes, Practice , Insect Vectors , Vaccination , Yellow Fever/drug therapy , Yellow Fever/prevention & control
15.
Rev. Assoc. Med. Bras. (1992) ; 64(2): 106-113, Feb. 2018. tab, graf
Article in English | LILACS | ID: biblio-1041014

ABSTRACT

Summary The yellow fever (YF) virus is a Flavivirus, transmitted by Haemagogus, Sabethes or Aedes aegypti mosquitoes. The disease is endemic in forest areas in Africa and Latin America leading to epizootics in monkeys that constitute the reservoir of the disease. There are two forms of YF: sylvatic, transmitted accidentally when approaching the forests, and urban, which can be perpetuated by Aedes aegypti. In Brazil, the last case of urban YF occurred in 1942. Since then, there has been an expansion of transmission areas from the North and Midwest regions to the South and Southeast. In 2017, the country faced an important outbreak of the disease mainly in the states of Minas Gerais, Espírito Santo and Rio de Janeiro. In 2018, its reach extended from Minas Gerais toward São Paulo. Yellow fever has an incubation period of 3 to 6 days and sudden onset of symptoms with high fever, myalgia, headache, nausea/vomiting and increased transaminases. The disease ranges from asymptomatic to severe forms. The most serious forms occur in around 15% of those infected, with high lethality rates. These forms lead to renal, hepatic and neurological impairment, and bleeding episodes. Treatment of mild and moderate forms is symptomatic, while severe and malignant forms depend on intensive care. Prevention is achieved by administering the vaccine, which is an effective (immunogenicity at 90-98%) and safe (0.4 severe events per 100,000 doses) measure. In 2018, the first transplants in the world due to YF were performed. There is also an attempt to evaluate the use of active drugs against the virus in order to reduce disease severity.


Subject(s)
Humans , Animals , Yellow Fever/diagnosis , Yellow Fever/prevention & control , Yellow Fever/transmission , Yellow Fever/epidemiology , Aedes , Insect Vectors , Brazil/epidemiology , Disease Outbreaks/prevention & control , Yellow Fever Vaccine/standards
16.
Mem. Inst. Oswaldo Cruz ; 113(2): 135-137, Feb. 2018.
Article in English | LILACS | ID: biblio-1040589

ABSTRACT

The yellow fever (YF) vaccine has been used since the 1930s to prevent YF, which is a severe infectious disease caused by the yellow fever virus (YFV), and mainly transmitted by Culicidae mosquitoes from the genera Aedes and Haemagogus . Until 2013, the World Health Organization (WHO) recommended the administration of a vaccine dose every ten years. A new recommendation of a single vaccine dose to confer life-long protection against YFV infection has since been established. Recent evidence published elsewhere suggests that at least a second dose is needed to fully protect against YF disease. Here, we discuss the feasibility of administering multiple doses, the necessity for a new and modern vaccine, and recommend that the WHO conveys a meeting to discuss YFV vaccination strategies for people living in or travelling to endemic areas.


Subject(s)
Humans , Yellow Fever/prevention & control , Yellow fever virus/immunology , Immunization Schedule , Antibodies, Neutralizing/immunology , Yellow Fever Vaccine/administration & dosage , Yellow Fever Vaccine/immunology
19.
Rev. chil. infectol ; 35(5): 587-590, 2018. tab
Article in Spanish | LILACS | ID: biblio-978074

ABSTRACT

Resumen La aparición de fiebre amarilla en las costas brasileñas, lugares de alto interés turístico, ha provocado una alta demanda de vacunación. Este articulo entrega respuestas a las principales consultas sobre la vacuna de fiebre amarilla y puede servir como guía para médicos no expertos en Medicina del Viajero.


Due to the recent yellow fever outbreak affecting the costal region of Brazil, including main touristic destinations, there is a high demand of yellow fever vaccination. This publication addresses the most relevant practical issues regarding this vaccine for tourists visiting Brazil and aims to serve as a guideline for non-expert physicians in Chile and elsewhere.


Subject(s)
Humans , Travel , Yellow Fever/prevention & control , Yellow Fever Vaccine/administration & dosage , Brazil , Chile
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