Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 11 de 11
Filter
1.
Ciênc. Saúde Colet ; 27(3): 861-870, mar. 2022. tab
Article in Portuguese | LILACS | ID: biblio-1364676

ABSTRACT

Resumo A epidemia zika trouxe ao cenário o nascimento de crianças com necessidades desconhecidas e inesperadas que exigem acompanhamento longitudinal, fortalecimento do vínculo, integralidade e coordenação do cuidado, atributos essenciais da atenção primária em saúde (APS). Este artigo tem o objetivo de avaliar a orientação da APS utilizando o instrumento PCATool-Brasil. Os dados foram coletados entre 2016 e 2019 por meio de entrevistas com responsáveis de crianças que nasceram em uma maternidade pública do Recife-PE no período crítico do surto de microcefalia, sobretudo no Nordeste do Brasil. Participaram do inquérito 109 responsáveis, dos quais 15,6% tiveram diagnóstico confirmado de microcefalia para suas crianças. Evidenciou-se a suficiência do grau de afiliação e acesso, mas a insuficiência da coordenação de cuidado, longitudinalidade, integralidade, orientação familiar e comunitária. No contexto da síndrome congênita da zika, esses atributos são imprescindíveis para o cuidado integral de crianças e famílias. A produção de saúde a partir desses domínios depende da orientação dos modelos de atenção e gestão com fortes investimentos estaduais e federal. A defesa da vida depende da capacidade de colocar a vida acima de todas as outras racionalidades.


Abstract The Zika epidemic brought to the fore the birth of children with unknown and unexpected needs that demand longitudinal follow-up, strengthening the bond, comprehensiveness and coordination of care in health, which are essential attributes of primary health care (PHC). This article aims to evaluate the orientation of PHC care, using the PCATool-Brasil. The data were collected between 2016 and 2019, by means of interviews with parents of children who were born in a public maternity hospital in Recife (state of Pernambuco) between October 2015 and February 2016, a critical period of the microcephaly outbreak, especially in the Northeast of Brazil. The parents of 109 children participated in the survey, 15.6% of which had a confirmed microcephaly diagnosis. The degree of affiliation and access was sufficient, but the aspects of coordination of care, longitudinality, comprehensiveness, family and community orientation were insufficient. In the context of congenital Zika syndrome, these attributes are essential for the care of children and families. The fostering of health from these domains depends on the orientation of the models of care and their management with state and federal investments. The defense of life depends on the ability to place life above all other rationalities.


Subject(s)
Humans , Female , Pregnancy , Child , Zika Virus , Zika Virus Infection/congenital , Zika Virus Infection/therapy , Microcephaly/therapy , Microcephaly/epidemiology , Primary Health Care , Brazil/epidemiology
2.
Ciênc. Saúde Colet ; 27(3): 881-894, mar. 2022. tab, graf
Article in English, Portuguese | LILACS | ID: biblio-1364707

ABSTRACT

Resumo A correlação do aumento na incidência de casos de microcefalia em 2015, simultaneamente ao surto do zika vírus, levou ao reconhecimento de uma epidemia pela síndrome congênita pelo vírus zika (SCVZ), que ressaltou as já conhecidas fragilidades nas ações do cuidado em saúde. O objetivo do artigo é analisar a rede virtual de informações sobre a oferta de serviços de saúde para crianças com SCVZ no Rio de Janeiro. A partir da análise de redes sociais, foram coletados dados de fontes virtuais sobre informações de serviços e instituições de atendimento, utilizando o buscador Google, a fim de avaliar as relações entre esses atores em 2018. Os resultados apresentaram uma rede fragmentada, com centralização em fontes virtuais e serviços públicos da atenção secundária e terciária, destacando-se a proximidade das fontes de imprensa com os serviços públicos. Destacou-se também o isolamento dos serviços privados e a não interlocução entre os serviços filantrópicos e os serviços públicos. Além disso, as informações oferecidas mostraram-se insuficientes e superficiais, apesar da lacuna da rede formal de reabilitação. Consequentemente, as evidências apontam para a importância de uma rede bem estabelecida de serviços, bem como a necessidade de fomentar a comunicação por meio de mídias virtuais.


Abstract In 2015 the correlation between increasing numbers of cases of microcephaly and a zika virus outbreak led to recognition of an epidemic of congenital zika virus syndrome (CZVS), highlighting well-known weaknesses in health care measures. This article examines the network of virtual information available on health service provision for children suffering from CZVS in Rio de Janeiro. Using social media analysis, data on information about services and care institutions were collected from virtual sources using the Google search engine, so as to assess relations among these actors in 2018. The results revealed a fragmented network centred on virtual sources and secondary and tertiary public care services, with striking proximity of press sources to public services. Also salient was the isolation of private services and the lack of dialogue between philanthropic and public services. Moreover, the information offered was found to be insufficient and superficial, despite the gaps in the formal rehabilitation network. The evidence thus suggested the importance of a well-established health care service network and the necessity of fostering communication through virtual media.


Subject(s)
Humans , Child , Zika Virus , Zika Virus Infection/complications , Zika Virus Infection/therapy , Zika Virus Infection/epidemiology , Microcephaly/epidemiology , Brazil/epidemiology , Social Network Analysis
3.
Medicina (B.Aires) ; 81(5): 817-836, oct. 2021. graf
Article in Spanish | LILACS | ID: biblio-1351056

ABSTRACT

Resumen El síndrome de Guillain-Barré (SGB) es una enfermedad inmunológica del nervio periférico y las raíces nerviosas, poco frecuente, potencialmente mortal y que suele desencadenarse por infecciones. La incidencia del SGB puede aumentar durante el brote de enfermedades infecciosas, tal como se observó en las epidemias del virus Zika en la Polinesia Francesa en 2013 y en América Latina en 2015. El diagnóstico y el manejo clínico del SGB pueden ser complicados ya que su presentación y el curso de la enfermedad son heterogéneos, y actualmente no se cuenta con guías clínicas internacionales. Para respaldar a los médicos, especialmente en el contexto de un brote de una enfermedad infecciosa, hemos desarrollado una guía clínica aplicable en todo el mundo para el diagnóstico y el tratamiento del SGB. La guía se basa en literatura actualizada y el consenso de expertos, y tiene una estructura de diez pasos para facilitar su uso en la práctica clínica. Inicialmente, brindamos una introducción a los criterios de diagnóstico, variantes clínicas y diagnósticos diferenciales del SGB. Los diez pasos luego abordan el reconocimiento y el diagnóstico temprano del SGB, la admisión a la unidad de cuidados intensivos, indicación y selección de tratamiento, seguimiento y tratamiento de la progresión de la enfermedad, predicción del curso clínico, resultados y tratamiento de complicaciones y secuelas.


Abstract Guillain-Barré syndrome (GBS) is a rare, but potentially fatal, immune-mediated disease of the peripheral nerves and nerve roots that is usually triggered by infections. The incidence of GBS can therefore increase during outbreaks of infectious diseases, as was seen during the Zika virus epidemics in 2013 in French Polynesia and in 2015 in Latin America. Diagnosis and management of GBS can be complicated as its clinical presentation and disease course are heterogeneous, and no international clinical guidelines are currently available. To support clinicians, especially in the context of an outbreak, we have developed a globally applicable guideline for the diagnosis and management of GBS. The guideline is based on current literature and expert consensus, and has a ten-step structure to facilitate its use in clinical practice. We first provide an introduction to the diag nostic criteria, clinical variants and differential diagnoses of GBS. The ten steps then cover early recognition and diagnosis of GBS, admission to the intensive care unit, treatment indication and selection, monitoring and treatment of disease progression, prediction of clinical course and outcome, and management of complications and sequelae.


Subject(s)
Humans , Guillain-Barre Syndrome/diagnosis , Guillain-Barre Syndrome/therapy , Guillain-Barre Syndrome/epidemiology , Zika Virus Infection/diagnosis , Zika Virus Infection/therapy , Zika Virus Infection/epidemiology , Incidence , Disease Outbreaks , Zika Virus
4.
Rev. Pesqui. (Univ. Fed. Estado Rio J., Online) ; 13: 692-697, jan.-dez. 2021. tab
Article in English, Portuguese | LILACS, BDENF | ID: biblio-1178219

ABSTRACT

Objetivo: Analisar o seguimento de crianças com microcefalia na Atenção Primária à Saúde, segundo relato de mães. Método: Pesquisa qualitativa, realizada com nove mães de crianças com microcefalia de um município de grande porte da Paraíba, por meio de entrevista semiestruturada. A interpretação dos dados seguiu os princípios da análise temática. Resultados: As mães relataram receber assistência pouco resolutiva devido à inexistência de uma rede articulada de cuidado em saúde; não valorizam o acompanhamento da Atenção Primária à Saúde para as crianças com microcefalia, preferindo consultar seus filhos com especialistas, comprometendo a oferta da atenção contínua e integral para a promoção da saúde infantil. Conclusão: É indispensável o fortalecimento da Rede de Atenção à Saúde, com construção de vínculo, tendo a Atenção Primária à Saúde como coordenadora e ordenadora do cuidado à criança com microcefalia


Objective: To analyse the follow-up of children with microcephaly in Primary Health Care, according to mothers report. Method: Qualitative research, conducted with nine mothers of children with microcephaly from a large city of Paraíba, through semi-structured interview. Data interpretation followed the principles of thematic analysis. Results: Mothers reported receiving poor care because of the lack of an articulated health care network; do not value the monitoring of Primary Health Care for children with microcephaly, choosing to consult their children with specialists, compromising the provision of continuous and comprehensive care for the promotion of child health. Conclusion: It is essential to strengthen the Health Care Network, with the construction of a bond, having Primary Health Care as coordinator and orderer of care for children with microcephaly


Objetivo: Comprender el seguimiento de los niños con microcefalia en atención primaria de salud, según el informe de las madres. Método: Investigación cualitativa, realizada con nueve madres de niños con microcefalia de una gran ciudad de Paraíba, por medio de una entrevista semiestructurada. La interpretación de los datos siguió los principios del análisis temático. Resultados: Las madres informaron que recibieron poca atención debido a la falta de una red articulada de atención médica; No valoramos el monitoreo de la Atención Primaria de Salud para niños con microcefalia, prefiriendo consultar a sus hijos con especialistas, comprometiendo la provisión de atención continua e integral para la promoción de la salud infantil. Conclusión: Es esencial fortalecer la Red de Atención Médica, con la construcción de un vínculo, teniendo la Atención Primaria de Salud como coordinador y encargado de la atención de niños con microcefalia


Subject(s)
Humans , Male , Female , Infant , Adult , Primary Health Care/methods , Zika Virus Infection/therapy , Microcephaly/therapy , Mother-Child Relations , Mothers/psychology , Child Health , Qualitative Research , Empathy
5.
Enferm. actual Costa Rica (Online) ; (36): 48-61, Jan.-Jun. 2019. tab, graf
Article in Portuguese | LILACS, BDENF | ID: biblio-1019829

ABSTRACT

Resumo O objetivo desta investigação foi identificar as orientações recebidas no pré-natal, as medidas preventivas utilizadas contra a infecção pelo Zika Vírus e o nível de ansiedade das gestantes com diagnóstico positivo de infecção por Zika. Realizou-se pesquisa descritiva e exploratória com abordagem quantitativa. Participaram 53 gestantes usuárias do serviço de pré-natal de Pontal do Araguaia-MT. Utilizou-se o Inventário de Ansiedade Traço-Estado instrumento validado para a coleta de dados. A análise dos dados foi realizada por meio da estatística descritiva simples. As gestantes receberam informações sobre o Zika Vírus com maior frequência de profissionais de saúde, durante as consultas de pré-natal, sendo os enfermeiros identificados como promotores de saúde, os maiores disseminadores do conhecimento e do empoderamento das gestantes. A maioria faz uso de medidas preventivas, sendo o uso do repelente e a limpeza do quintal as mais frequentes. As gestantes que tiveram diagnóstico positivo para Zika Vírus, apresentaram escores de ansiedade-Traço/Estado elevados. Concluise que a orientação qualificada sobre Zika Vírus no pré-natal é fundamental à redução da ansiedade, e que são os profissionais de saúde que capacitam as gestantes contra o ambiente repelente.


Resumen El objetivo de esta investigación fue identificar las orientaciones recibidas en el prenatal, las medidas preventivas utilizadas contra la infección por el Virus Zika y el nivel de ansiedad de las mujeres embazadas con diagnóstico positivo de infección por Zika. Se realizó una investigación descriptiva con abordaje cuantitativo. Participaron 53 gestantes usuarias del servicio de prenatal de Pontal do Araguaia-MT. Se utilizó la entrevista semiestructurada y el Inventario de Ansiedad Traza-Estado como instrumentos para la recolección de datos. El análisis de los datos fue realizado por medio de la estadística descriptiva simple. Las gestantes recibieron información sobre el virus Zika con mayor frecuencia de profesionales de salud, durante las consultas de prenatal, siendo los enfermeros identificados como promotores de salud, los mayores diseminadores del conocimiento y del empoderamiento de las gestantes. La mayoría hace uso de medidas preventivas, siendo el uso del repelente y la limpieza del quintal las más frecuentes. Las gestantes que tuvieron diagnóstico positivo para virus Zika, presentaron puntajes de ansiedad-Trazo / Estado elevados. Se concluye que la orientación cualificada sobre el virus Zika en el prenatal es fundamental para la reducción de la ansiedad, y que sean los profesionales de salud quienes empoderen a las gestantes frente al medio repelente.


Abstract The aim of this research was to identify the guidelines received in prenatal care, the preventive measures used against Zika virus infection and the level of anxiety of pregnant women with a positive diagnosis of Zika infection. A descriptive and exploratory research with a quantitative approach was carried out. Participants were 53 pregnant women users of the prenatal service of Pontal do Araguaia-MT. The semi-structured interview and theTrait-State Anxiety Inventory (IDATE) were used as instruments for data collection. Data analysis was performed using simple descriptive statistics. The pregnant women received information abou tthe Zika Virus in a higher frequency of health professionals during the prenatal consultations, with the nurses identified as health promoters, the greatest disseminators of knowledge and empowerment of pregnant women. Most make use of preventive measures, being the use of the repellent and the cleaning of the yard the most frequent ones. Pregnant women who had a positive diagnosis for Zika Virus had high anxiety / Trace / State scores. It was concluded that the qualified guidance on zika virus in prenatal care is fundamental to the reduction of anxiety, and that it is the health professionals who empower pregnant women against there pellent environment.


Subject(s)
Female , Adolescent , Adult , Anxiety/therapy , Prenatal Care , Brazil , Pregnancy , Pregnant Women , Zika Virus , Zika Virus Infection/therapy , Health Promotion
6.
Rev. Soc. Bras. Med. Trop ; 51(3): 261-269, Apr.-June 2018. tab, graf
Article in English | LILACS | ID: biblio-957430

ABSTRACT

Abstract The objective of this study was to integrate findings related to Zika virus from the scientific literature. An integrative review of Medline was conducted, and data search was performed using the Health Sciences Descriptor Zika virus and the following filters: full texts available; studies in humans; full articles; and publications in Portuguese, French, English, and Spanish. After application of the filters, followed by reading of the titles, abstracts, and full texts, 44 studies were included in the review, for which content analysis was performed. A large part of the literature comprised review articles (84%; N=37); the majority was in English (95%, N=42). In 2016, 84% (N=37) of our sample articles was published, while in 2017, 16% (N=7) was published. The main form of viral transmission was thorough the mosquito Aedes aegypti (N=30). In addition, sexual transmission (N=09), transmission through blood transfusion (N=16), vertical transmission (N=21) and transmission from occupational activities (N=03) occurred. It was possible to diagnose the disease by testing blood (N=22), urine (N=14), saliva (N=06), semen/sperm (N=03), cerebrospinal and amniotic fluid, and other tissues (N=02). Symptomatology occurred in 1-5 people (N=10) between 3 and 7 days after a mosquito bite (N=09). Complications observed were Guillain Barré syndrome (N=27); neurological Zika syndrome (N=27); meningitis, meningoencephalitis, and myelitis (N=07); deaths and/or newborns (N=03). The review provides scientific evidence that contributes to the care, planning and implementation of public policies.


Subject(s)
Humans , Animals , Aedes/virology , Zika Virus Infection/complications , Zika Virus Infection/diagnosis , Zika Virus Infection/therapy , Mosquito Vectors/virology , Zika Virus , Zika Virus Infection
7.
Mem. Inst. Oswaldo Cruz ; 113(10): e180290, 2018. graf
Article in English | LILACS | ID: biblio-955105

ABSTRACT

BACKGROUND Zika has emerged as a new public health threat after the explosive epidemic in Brazil in 2015. It is an arbovirus transmitted mainly by Aedes aegypti mosquitoes. The knowledge of physiological, behavioural and biological features in virus-infected vectors may help the understanding of arbovirus transmission dynamics and elucidate their influence in vector capacity. OBJECTIVES We aimed to investigate the effects of Zika virus (ZIKV) infection in the behaviour of Ae. aegypti females by analysing the locomotor activity, egg production and viability. METHODOLOGY Ae. aegypti females were orally infected with ZIKV through an artificial feeder to access egg production, egg viability and locomotor activity. For egg production and viability assays, females were kept in cages containing an artificial site for oviposition and eggs were counted. Locomotor activity assays were performed in activity monitors and an average of 5th, 6th and 7th days after infective feeding was calculated. FINDINGS No significant difference in the number of eggs laid per females neither in their viability were found between ZIKV infected and non-infected females, regardless the tested pair of mosquito population and virus strain and the gonotrophic cycles. Locomotor activity assays were performed regardless of the locomotor activity in ZIKV infected females was observed, in both LD and DD conditions. MAIN CONCLUSIONS The lower locomotor activity may reduce the mobility of the mosquitoes and may explain case clustering within households reported during Zika outbreaks such as in Rio de Janeiro 2015. Nevertheless, the mosquitoes infected with ZIKV are still able to disseminate and to transmit the disease, especially in places where there are many oviposition sites.


Subject(s)
Animals , Zika Virus , Zika Virus Infection/diagnosis , Zika Virus Infection/therapy , Zika Virus Infection/transmission , Aedes
8.
Mem. Inst. Oswaldo Cruz ; 113(5): e170398, 2018. graf
Article in English | LILACS | ID: biblio-894919

ABSTRACT

Since the 1940s, French Guiana has implemented vector control to contain or eliminate malaria, yellow fever, and, recently, dengue, chikungunya, and Zika. Over time, strategies have evolved depending on the location, efficacy of the methods, development of insecticide resistance, and advances in vector control techniques. This review summarises the history of vector control in French Guiana by reporting the records found in the private archives of the Institute Pasteur in French Guiana and those accessible in libraries worldwide. This publication highlights successes and failures in vector control and identifies the constraints and expectations for vector control in this French overseas territory in the Americas.


Subject(s)
Humans , Chikungunya Fever/transmission , Zika Virus Infection/therapy , Mosquito Vectors/classification
9.
Rev. gaúch. enferm ; 39: e20180025, 2018.
Article in Portuguese | LILACS, BDENF | ID: biblio-978482

ABSTRACT

Resumo OBJETIVO Compreender os conhecimentos, as percepções e as práticas de cuidados de mulheres que contraíram o Zika vírus na gestação. MÉTODOS Estudo qualitativo, descritivo-exploratório. A coleta de dados ocorreu com 10 mulheres que contraíram o Zika vírus na gestação, através de entrevista aberta, em um município da Região Centro-Oeste, Brasil, em 2017. A análise de conteúdo temática permitiu apresentar duas categorias. O estudo respeitou os aspectos éticos para as pesquisas com seres humanos. RESULTADOS O conhecimento das gestantes infectadas se mostrou reduzido a poucas informações, sendo a fonte das informações a internet e a televisão, com pouca expressão dos serviços de saúde. Medo e a preocupação com o bebê estão presentes nos sentimentos influenciando as práticas de cuidado no período da gestação. CONCLUSÃO As gestantes recebem poucas informações dos serviços de saúde e suas práticas de prevenção se relacionam com o medo de transmitir a infecção para o bebê durante a gestação.


Resumen OBJETIVO Comprender los conocimientos, las percepciones y las prácticas de cuidado de las mujeres que contrajeron el Zika virus en la gestación. MÉTODOS Estudio cualitativo, descriptivo-exploratorio. Se recolectaron datos de 10 mujeres que contrajeron el Zika virus en la gestación, a través de una entrevista abierta, en un municipio de la Región Centro-Oeste, Brasil, en 2017. El análisis de contenido temático permitió presentar dos categorías. El estudio respetó los aspectos éticos para las investigaciones con seres humanos. RESULTADOS El conocimiento de las gestantes infectadas se mostró reducido a pocas informaciones, siendo la fuente de informaciones internet y la televisión, con poca expresión de los servicios de salud. El miedo y la preocupación con el bebé están presentes en los sentimientos, influenciando las prácticas de cuidado en el período de la gestación. CONCLUSIÓN Las gestantes reciben poca información de los servicios de salud y sus prácticas de prevención se relacionan con el miedo de transmitir la infección al bebé durante la gestación.


Abstract OBJECTIVE To understand the knowledge, perceptions and care practices of women who have contracted the Zika virus during pregnancy. METHODS Qualitative, descriptive-exploratory study. The data collection was carried out with 10 women who contracted the Zika virus during pregnancy, through an open interview in a municipality of the Central-West Region, Brazil, in 2017. The analysis of the thematic content allowed to present two categories. The study respected the ethical aspects for research with human beings. RESULTS The knowledge of infected pregnant women was reduced to little information, being the source of the information the Internet and the television, with little expression of the health services. Fear and concern about the baby are present in the feelings influencing the care practices in the gestation period. CONCLUSION Pregnant women receive little information from the health services and their prevention practices are related to the fear of transmitting the infection to the baby during pregnancy.


Subject(s)
Humans , Female , Pregnancy , Adolescent , Adult , Young Adult , Pregnancy Complications, Infectious/therapy , Attitude to Health , Health Knowledge, Attitudes, Practice , Zika Virus Infection/therapy
10.
Rev. bras. ginecol. obstet ; 39(5): 235-248, May 2017. tab, graf
Article in English | LILACS | ID: biblio-898859

ABSTRACT

Abstract From the discovery of the Zika virus (ZIKV) in 1947 in Uganda (Africa), until its arrival in South America, it was not known that it would affect human reproductive life so severely. Today, damagetothe central nervous system is known to be multiple, and microcephaly is considered the tip of the iceberg. Microcephaly actually represents the epilogue of this infection's devastating process on the central nervous system of embryos and fetuses. As a result of central nervous system aggression by the ZIKV, this infection brings the possibility of arthrogryposis, dysphagia, deafness and visual impairment. All of these changes of varying severity directly or indirectly compromise the future life of these children, and are already considered a congenital syndrome linked to the ZIKV. Diagnosis is one of the main difficulties in the approach of this infection. Considering the clinical part, it has manifestations common to infections by the dengue virus and the chikungunya fever, varying only in subjective intensities. The most frequent clinical variables are rash, febrile state, non-purulent conjunctivitis and arthralgia, among others. In terms of laboratory resources, there are also limitations to the subsidiary diagnosis. Molecular biology tests are based on polymerase chain reaction (PCR)with reverse transcriptase (RT) action, since the ZIKV is a ribonucleic acid (RNA) virus. The RT-PCR shows serum or plasma positivity for a short period of time, no more than five days after the onset of the signs and symptoms. The ZIKVurine test is positive for a longer period, up to 14 days. There are still no reliable techniques for the serological diagnosis of this infection. If there are no complications (meningoencephalitis or Guillain-Barré syndrome), further examination is unnecessary to assess systemic impairment. However, evidence is needed to rule out other infections that also cause rashes, such as dengue, chikungunya, syphilis, toxoplasmosis, cytomegalovirus, rubella, and herpes. There is no specific antiviral therapy against ZIKV, and the therapeutic approach to infected pregnant women is limited to the use of antipyretics and analgesics. Anti-inflammatory drugs should be avoided until the diagnosis of dengue is discarded. There is no need to modify the schedule of prenatal visits for pregnant women infected by ZIKV, but it is necessary to guarantee three ultrasound examinations during pregnancy for low-risk pregnancies, and monthly for pregnant women with confirmed ZIKV infection. Vaginal delivery and natural breastfeeding are advised.


Resumo Desde a descoberta do vírus Zika (VZIK) em 1947 em Uganda, na África, até sua chegada na América do Sul, não se tinha notícia de que ele seria capaz de comprometer a vida reprodutiva emhumanos de forma tão severa.Hoje, sabe-se que os danos sobre o sistema nervoso central são múltiplos, e a microcefalia é considerada a ponta do iceberg, visto que na realidade ela representa o epílogo de um processo devastador desta infecção sobre o sistema nervoso central do embrião e do feto. Em decorrência da agressão do sistema nervoso central pelo VZIK, esta infecção pode provocar artrogripose, disfagia, surdez e comprometimento visual. Todas estas alterações, de gravidade variável, direta ou indiretamente comprometem a vida futura dessas crianças, já sendo considerada uma síndrome congênita ligada aoVZIK. Uma das principais dificuldades na abordagemdessa infecção é relativa ao diagnóstico. Considerando a parte clínica, observa-se que ela apresenta manifestações comuns às infecções pelos vírus da dengue e da febre chikungunya, variando apenasemsuas intensidades subjetivas. As variáveis clínicas mais frequentes são o exantema, febrícula, conjuntivite não purulenta e artralgia. No tocante aos recursos laboratoriais, também existem limitações ao diagnóstico subsidiário. As provas de biologia molecular se fundamentam na reação em cadeia da polimerase (RCP) com ação da transcriptase reversa (TT), visto que o VZIK é umvírus ácido ribonucleico (ARN). ATRRCP apresenta positividade sérica ou plasmática por um período curto de tempo, não ultrapassando cinco dias após início dos sinais e sintomas. Esta pesquisa do VZIK na urina fica positiva por período mais prolongado, chegando a 14 dias. Ainda não existem técnicas seguras para diagnóstico sorológico dessa infecção. Não havendo complicações (meningoencefalite ou síndrome de Guillain-Barré), dificilmente são necessários mais exames complementares para avaliar o comprometimento sistêmico.No entanto, são necessáriasprovaspara descartar as outras infecções que causam exantema, como dengue, chikungunya, sífilis, toxoplasmose, citomegalovírus, rubéola e herpes. Sabe-se que não existe terapia antiviral específica contra o VZIK, e a abordagem terapêutica de gestantes portadoras da infecção limita-se ao uso de antitérmicos e analgésicos. Orienta-se evitar anti-inflamatórios até que o diagnóstico de dengue seja descartado. Sobre a condução do pré-natal, não há necessidade de modificar o cronograma de consultas pré-natais para gestantes que foram infectadas pelo VZIK, mas é necessária a garantia de três exames ecográficos durante a gravidez para gestantes de baixo risco, emensais para a gestante cominfecção confirmada pelo VZIK. Avia de parto é vaginal, e está liberado o aleitamento natural.


Subject(s)
Humans , Female , Pregnancy , Infant, Newborn , Pregnancy Complications, Infectious/diagnosis , Pregnancy Complications, Infectious/therapy , Zika Virus Infection/diagnosis , Zika Virus Infection/therapy , Zika Virus Infection/transmission , Microcephaly/virology , Prenatal Care , Microcephaly/diagnosis , Microcephaly/embryology , Microcephaly/therapy
11.
Rev. Hosp. Clin. Univ. Chile ; 26(4): 277-284, 2015. ilus
Article in Spanish | LILACS | ID: biblio-831260

ABSTRACT

Zika virus is an arbovirus that was first discovered in Africa in 1947. Until some time ago, it was an unnoticed emergent virus, due to its low epidemiological impact and its mild flu-like symptoms. However, from 2007 on, Zika virus started to propagate throughout the world and was first locally transmitted in America in 2015. Since then, autochthonous cases of Zika infection have been reported on 33 countries of the Americas. The most relevant impact of the Zika virus outspread is its supposed link to the increase in birth defects and microcephaly in newborns in regions with high Zika virus infection incidence during the past two years. Therefore, the World Health Organization declared Zika virus a public health emergency of international concern. This review describes Zika virus epidemiology, transmission mechanisms and pathogeny, such as its clinical presentation, adverse fetal outcomes, diagnosis, treatment and current recommendations for transmission prevention.


Subject(s)
Humans , Male , Female , Zika Virus Infection/epidemiology , Zika Virus Infection/parasitology , Zika Virus Infection/prevention & control , Zika Virus Infection/therapy , Zika Virus Infection/transmission , Zika Virus/pathogenicity
SELECTION OF CITATIONS
SEARCH DETAIL