RESUMEN
Bone substitute biomaterials can prevent severe root resorptions during orthodontic treatments by induction of new bone formation leading in more healthy periodontal status after treatment. Furthermore, NanoBone[TM] graft offers several advantages to be applied in the surgery defects due to its nanocrystalline hydroxy apatite components and nanosized biomaterial structures. The purpose of this study was to evaluate the tissue reactions in the socket preservation using NanoBone[TM] following orthodontic tooth movement. In this experimental study, 4 dogs were selected of the mixed race following defects preparations in the mesial aspect of the first premolar in each quadrant of the animals. NanoBone[TM] was applied in one side as a case region while the opposite side remained hollow as a control side. The first premolar was moved mesially using orthodontic forces and the orthodontic tooth movement was calculated at different time intervals. When the teeth reached half the way, the animals were sacrificed and the sections were subjected to histopathologic assessments. The orthodontic tooth movement values were analyzed using three-way ANOVA test. The mean overall premolar movement towards canine in the socket filled with NanoBone[TM] was 1.076mm while it was 1.203mm in the control side. No significant differences were noted regarding the graft material, the time and jaw position. Root resoprtion was evident in the pressure regions of both groups and new bone formation was noted in the defects filled using NanoBone[TM]. It was concluded that NanoBone[TM] has osteoconductive properties with the decreased root resoprtion due to the limited tooth movements. Therefore, the tooth can be moved into the NanoBone[TM] graft material and the graft can be used as a substitution for autogenous bone during orthodontic tooth movements