[Light chains type multiple myeloma and amyloid intestinal obstruction]

A case of light chain type multiple myeloma is diagnosed in a 26 year-old patient who presented a gastrointestinal amyloidosis revealed by an intestinal obstruction. The authors recall the diagnostic difficulties of non typical multiple myeloma, the links between multiple myeloma and amyloidosis and emphasize their bad prognosis when associated

Alpha heavy chains disease: an intermediate stage

The authors report a case of alpha heavy chains disease associated with a lambliasis affecting a forty-year-old Moroccan women. Histologically, the stage of this case has not been described yet. It is intermediate between the stage A and B: there is a transparietal and plasmocytic infiltration of the small bowel as well as a ganglionic and periganglionic mesenteric infiltration and without any immunoblastic participation. This particularity warrents the tetracycline and cyclophosphamid association. This study is completed with a review of literature dealing with the alpha heavy chains disease