Haloperidol induced variations in hematological indices

It is essential for the effective management of drug action to understand the underlying pathogenesis of hematological dyscrasias. Hematological side effects of neuroleptic drugs occur infrequently but remain a potential cause of serious toxicity. The risk of butyrophenone induced blood dyscrasias seems to be underestimated in the literature, therefore we decided to report this as an animal model evaluation. The present work was undertaken to investigate the effect of typical antipsychotic drug [Haloperidol- 0.2mg/Kg], both as purified and commercially available form administered to rats [n=15], on hematological indices. Data of the present study suggests that the chronic administration of haloperidol may cause iron deficiency anemia. Although the morphological changes were more obvious in case of purified haloperidol treated rats as compared to the commercially available injections

Fishhook injury of the eye: a case report

Eye injuries caused by fishhooks are rare but there have been reports in the past with the hook either abrading the cornea or piercing the lid, orbital tissues or the eyeball. This is a case report of an Omani boy admitted with a penetrating injury of the left eyeball caused by a fishhook. The hook was successfully removed after surgically extending the wound. The wound was anterior and damage to the choroid and retina was minimal which helped in the restoration of normal vision, the child was followed up for a period of more than two years without any complications