Detection of chlamydia trachomatis DNA by polymerase chain reaction in urine of women with tubal infertility as diagnosed by hysterosalpingography and laparoscopy

This study included 30 women with tubal infertility and 14 women with other causes of infertility documented by laparoscopy. The presence of C. trachomatis DNA in first void urine was determined using PCR assay and the presence of C. trachomatis-specific IgG in serum samples was also investigated using microimmunofluorescence [MIF] technique. C. trachomatis-specific IgG was present in 14 of 30 women with tubal infertility compared with seven of 14 with other causes of infertility. In conclusion, there was a strong association between the presence of C. trachomatis DNA and the development of chlamydial- associated infertility

Auto-immune laboratory tests profile of low frequency syndrome patients

Special form of sensori-neural hearing loss [low frequency syndrome] was studied for autoimmune profile. Routine laboratory tests and antigen nonspecific tests [IgG, IgA, IgM and Clq] were carried out. Detection of autoantibodies [ANA, AMA and ASMA] were also done. There was a striking hyperglobulinemia and detection of autoantibodies. The positive screening tests of an autoimmune profile suggested type II or type III immunologic mechanism of injury