Neutrophil phagocytic power in diabetes mellitus

It was found that the phagocytic activity of the neutrophils in diabetic patients was significantly impaired when compared to the control group. But on comparing the 2 uncontrolled groups with each other, we found no significant difference which can explain the presence or abscence of infection. A significant defect in the serum of the uncontrolled diabetics was observed when compared with the serum of controlled diabetics. Also, there was inverse correlation between the phagocytic activity and blood glucose level. Although insulin treatment does not restore the phagocytic power to normal level, but this lowering of blood surgar offers some support to their defensive mechanisms