Relationship between obesity and cardiovascular risk factors in adults living in central Iran: results of Isfahan healthy heart program

As previous studies on the association between obesity and cardiovascular [CVD] risk factors have been made in limited populations, this study was performed to determine the association in 3 cities in the central parts of Iran. In this cross-sectional study, data collected in the1st phase of the Isfahan Healthy Heart Program [IHHP], involving 12514 subjects "19 years old, conducted during 2000-2001, in Isfahan and the Central Provinces of Iran, were analyzed. Fasting blood sugar [FBS], 2-hour post-load plasma glucose [2hpp], serum lipid profile, anthropometric parameters and blood pressure were determined by standard methods. FBS, 2hpp, serum lipids fractions [except for HDL-C] and blood pressure had significant positive relations with body mass index [BMI] and waist circumference [WC] [all p-values < 0.001]. As compared to the 1st quartile of WC, odds ratios [OR; 95% CI] of hypertension, diabetes and dyslipidemia in the 4th quartile were 2.8 [1.2-3.3], 3 [1.6-4.3] and 2.4 [1.9-3.1] in men and 2.5 [1.8-3.4], 2.7 [1.3-3.8] and 2.5 [2-3.2] in women, respectively. Also, ORs [95% CI] of hypertension, diabetes and dyslipidemic in 4th quartile of BMI, as compared to the 1st, were 1.6 [1.2-2], 2.8 [1.7-3.9] and 3 [2.4-3.8] in men and 1.9 [1.4-2.4], 2.6 [1.4-3.7] and 1.6 [1.2-2] in women, respectively. ORs of these risk facrors increased with increasing WC and BMI. Therefore, it is concluded that both obesity indicators increase the chance of CVD risk factors

Giant chondroid syringoma of the upper nasal orbital rim

The present study describes clinical manifestation, histopathologic findings and differential diagnosis of a first-reported case of giant chondroid syringoma [CS] of the upper nasal orbital rim. A 35-yr-old man with cranial palsy [CP] and a tumor of 3x3x4 cm in the upper nasal orbital rim of the left eye was referred to the eye clinic. The tumor was reported to have developed gradually over the years. It was removed under general anesthesia and no recurrence was observed during the one-year follow-up without any complaint from the patient. Macroscopic examination showed a whitish, irregular and relatively soft nodule of 3x2.5x 2 cm. and with calcificated spots on its section. Microscopically, tubules of various sizes were observed which were surrounded by cellular stroma and distinct areas of chondroid proliferation with no malignant changes. CS may assume a giant size, appearing as hard, slow-developing cutaneous and subcutaneous nodules on differential diagnosis. Despite favorable prognosis, the recurrence of CS is reported only in those patients whose tumors are not completely removed