RESUMEN
Background: nerve agents are among the chemicals used for military purposes. These agents belong to a group of Phosphoric acid organic esters that are extremely toxic and may cause severe damages or morbidity in human beings, animals and plants. This family includes G [Tabun, Sarin. Soman] and V [VE, VM, VX] agents
Materials and methods: in this review article, we reviewed resources available online and paper based libraries. Key words used in the search included: Cardiovascular effect, Management, Morbidity, Mortality, Nerve agent, Treatment. Total of 30 articIes were reviewed and data was extracted from 14 ones
Results: nerve agents have CNS and cardiovascular effects. Cardiovascular effects and manifestations of these agents are mainly related to muscarinic and nicotinic receptor action. Arrhythmias associated with these agents range from bradycardia to atrioventricular block and AV dissociation. The effect of the above mentioned agents on heart rate is in the form of bradycardia which is not clinically documented
Conclusion: treatment includes pre and post exposure measures. Resuscitation, source decontamination, ventilation, suction, atropine injection and use of oxygen and anticonvulsants are principles of treatment