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1.
Journal of the Egyptian National Cancer Institute. 1984; 1 (3): 17-31
en Inglés | IMEMR | ID: emr-106128

RESUMEN

The sera of 25 patients suffering from advanced stages [T3 and T4] of carcinoma of the bilharzial urinary bladder were examined for serum proteins and immunoglobulin levels. In addition, sera of 16 bilharzial cystitis patients and of 16 normal healthy individuals were included in the study. While there was a reduction in the albumin level and an increase in alpha-1, alpha-2, and gamma globulin levels in the sera of the 25 cancer patients, the beta globulins remained apparently unchanged and the alpha-2/beta ratio had therefore inverted values [1.5] as compared to normal controls [0.9]. A definite increase in IgG, IgA, IgM and IgE fractions in bilharzial bladder cancer patients was found. The immunoglobulin levels were higher in patients with T3 than with T4 lesions. On the other hand, there was a marked decrease in the non-immunoglobulin component[s] in sera of the cancer patients. This decrease was noted more in patients with T4 than in those with T3 lesions. Serum proteins and immunoglobulins in the bilharzial cystitis patients had intermediate values more or less midway between the bladder cancer patients and the normal controls


Asunto(s)
Humanos , Masculino , Esquistosomiasis , Inmunoglobulinas/sangre , Proteínas/sangre , Electroforesis de las Proteínas Sanguíneas
2.
Journal of the Egyptian National Cancer Institute. 1984; 1 (3): 45-56
en Inglés | IMEMR | ID: emr-106130

RESUMEN

The sera of 90 lymphoma and 60 leukemic patients were studied for the presence of either HBsAg or anti-HBs using counter-electrophoresis. In addition, the study included 40 breast cancer patients and 20 normal healthy subjects as controls. The findings indicated a close and specific association between hepatitis B infection and leukemia. The frequency of exposure in leukemia patients was 17% compared to 5% in the other groups. Acute leukemia cases with positive HBsAg or anti-HBs reactions indicated a group with very bad prognosis. The causal relationship of hepatitis B virus to certain types of leukemias was discussed


Asunto(s)
Humanos , Masculino , Femenino , Antígenos de Superficie de la Hepatitis B/sangre , Incidencia , Linfoma , Leucemia , Neoplasias de la Mama
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