Urinary FSH versus recombinant FSH in clomiphene citrate-resistant anovulatory patients, effectiveness and cost-effectiveness

Recombinant FSH [r-FSH] and urinary FSH [u-FSH] have been repeatedly compared in trials dealing with superovulation induction for IVF. 50 women, suffering WHO group II anovulatory mntertmlity and clomiphene citrate resistance were included in this study. Patients were divided into 2 groups: Group I [u-FSH group, n:25] and Group II [r-FSH group, n:25]. Details of ovarian response, FSH dose used and duration of the 100 stimulation cycles are presented. r-FSH may result in a better outcome in IUI cycles for unexplained infertility, while urinary FSH performed better in older women than recombinant FSH when associated with the long protocol