RESUMEN
To study the epidemiology, etiology and management of maxillary sinus tumors, using parameters like age, sex, socio-economic status, extent of spread, treatment offered and survival rate, and observe if there were any disease outcomes i.e. prognostic factors.Retrospective, descriptive study from Oct. 1997 to Sept. 2003.Dept. of ENT-Head and Neck Surgery, Jinnah Postgraduate Medical Centre, Karachi.45 cases with Maxillary Sinus Carcinoma.The data of all the patients was collected and analyzed.This study revealed that out of the 45 cases, 66% were in the 5th and 6th decade of life. Two-thirds of cases were males, with main presenting symptoms of cheek swelling and nasal obstruction. Most patients presented in Stage 3 with no nodes. Treatment with combined modality i.e. surgery followed by radiotherapy gave a 50% two year survival rate in these cases
RESUMEN
The objective of this clinical trial was to asses the efficacy of topical quinolones and compare it with the most commonly used aminoglycoside [gentamicin hydrocortisone] ear drops. Patients and methods: One hundred and twenty patients were recruited in this comparative clinical trial and divided into two groups: aminoglycoside group of 60 patients were treated with gentamycin hydrocortisone ear drops and quinolone group of 60 patients were prescribed norfloxacin topical solution with a dose of 6 drops in the affected ear twice daily for two weeks. In the aminoglycoside group 30 patients had complete cessation of the discharge, in 12 discharge decreased in amount and mucoid in nature and 18 had no change in the amount and nature of discharge. In the quinolone group in 43 patients discharge stopped completely, in 12 discharge reduced and became mucoid whereas in 5 no change in the amount and nature of the discharge occurred. We recommend that in the medical management of chronic suppurative otitis media, the topical quinolones should be considered first line of treatment as there are no ototoxic effects of quinolones, which can be used safely in the presence of tympanic membrane perforation