Natural antioxidants in the management of Parkinson's disease: Review of evidence from cell line and animal models / 中西医结合学报

Parkinson's disease (PD) is a chronic progressive neurodegenerative disease. It results from the death of dopaminergic neurons. The pathophysiological mechanisms in idiopathic PD include the production of α-synuclein and mitochondrial respiratory function-affecting complex I, caused by reactive oxygen species. Therefore, the use of natural antioxidants in PD may provide an alternative therapy that prevents oxidative stress and reduces disease progression. In this review, the effects of hydroxytyrosol, Ginkgo biloba, Withania somnifera, curcumin, green tea, and Hypericum perforatum in PD animal and cell line models are compared and discussed. The reviewed antioxidants show evidence of protecting neural cells from oxidative stress in animal and cell models of PD. However, the clinical efficacy of these phytochemicals needs to be optimised and further investigated.

A Rehabilitation of Missing Maxillary Anterior Teeth in a Severe Skeletal Class III Malocclusion Patient Requiring Implants

@#Management of traumatic dental injuries (TDI) in a young patient may range from simple to complex. In a situation where teeth are lost, a reliable and conservative treatment option is an implant-supported fixed dental prosthesis (i-FDP), as this treatment option negates the need to prepare sound abutment teeth as in the case of conventional fixed bridges. However, the placement of implants is usually prosthetically driven to allow for a 3D functional and aesthetic restoration. In the presence of severe skeletal Class III malocclusion, treatment may incorporate pre-surgical orthodontic treatment, followed by jaw surgery to correct the skeletal discrepancies and finally post-surgical orthodontic treatment before the rehabilitation with implants. A multidisciplinary treatment approach in a stepwise manner is required to address the patient’s overall treatment needs. This case report presents a joint prosthodontics, orthodontics and oral maxillofacial surgical management of a young adult male patient with a Skeletal Class III malocclusion who required rehabilitation of avulsed missing anterior teeth sustained from childhood TDI. The severity of the skeletal relationship required a Le Fort I maxillary advancement and a bilateral sagittal split osteotomy for the setback of the mandible in combination with orthodontics for correction of malocclusion and arch relationship prior to implant placement. Correction of the malocclusion and jaw deformity allowed the functional and aesthetic rehabilitation of the missing teeth using an i-FDP.

Management of Laryngopharyngeal Reflux in Asia

Objectives@#. This study was conducted to investigate the current practices of Asian otolaryngologists for laryngopharyngeal reflux (LPR). @*Methods@#. An online survey about LPR was sent to 2,000 members of Asian otolaryngological societies, and a subgroup analysis was performed between Western and Eastern Asian otolaryngologists. The survey was conducted by the Laryngopharyngeal Reflux Study Group of Young Otolaryngologists of the International Federation of Oto-rhino-laryngological Societies. @*Results@#. Among approximately 1,600 Asian otolaryngologists, 146 completed the survey (62 from Western Asian countries, 84 from Eastern Asian countries). A substantial majority (73.3%) of the otolaryngologists considered LPR and gastroesophageal reflux disease to be different diseases. The symptoms thought to be closely related to LPR were coughing after lying down, throat clearing, and globus sensation. The findings thought to be closely related to LPR were posterior commissure granulations and hypertrophy, arytenoids, and laryngeal erythema. The respondents indicated that they mostly diagnosed LPR (70%) after an empirical therapeutic trial of proton pump inhibitors (PPIs). Although multichannel intraluminal impedance-pH (MII-pH) monitoring is a useful tool for diagnosing nonacid or mixed LPR, 78% of Asian otolaryngologists never or very rarely used MII-pH. Eastern Asian otolaryngologists more frequently used once-daily PPIs (64.3% vs. 45.2%, P=0.021), whereas Western Asian otolaryngologists preferred to use twice-daily PPIs (58.1% vs. 39.3%, P=0.025). The poor dietary habits of patients were considered to be the main reason for therapeutic failure by Asian otolaryngologists (53.8%). Only 48.6% of Asian otolaryngologists considered themselves to be adequately knowledgeable and skilled regarding LPR. @*Conclusion@#. Significant differences exist between Western and Eastern Asian otolaryngologists in the diagnosis and treatment of LPR. Future consensus statements are needed to establish diagnostic criteria and therapeutic regimens.

Incidence of Atrial Fibrillation (AF) in Patients of Acute Coronary Syndrome

Introduction: Atrial fibrillation is common among patients withcardiovascular disease and is a frequent complication of theacute coronary syndrome.Objective: In this study our main goal is to assess theincidence of AF in patients of acute coronary syndrome.Method: This retrospective observational cohort study wasdone at Dhaka medical college and hospital from December2010 to December 2011 where 100 patients (male=73,female=27) were diagnosed with of ACS and AF. All data wereentered on the Statistical Package for Social Science (SPSS)and analyzed.Results: During the study most of the patients were belong to51-60 age group (53%) and 53% patients developed atrialfibrillation after admission. Also new onset AF patient’s hospitalstay rate was higher.Conclusion: After many analyses we can said that, incidenceof new-onset AF was more common in patients presenting withACS.

Prevalence of Hepatitis B Infection Among Kidney Patient Attending for Haemodialysis in Gazi Medical College Centre, Khulna, Bangladesh

Kidney disease is increasing day by day in the form of AKD orCKD. CKD patients who have developing end stage renaldisease (ESRD) required haemodialysis for survival. There is apotential risk of increasing blood borne viral infectionparticularly Hepatitis B infection. The proportion of hepatitis Binfection increasing with increased frequency of dialysis. Therisk is 1.47 times more in the patients receiving haemodialysis.We have a retrospective study. The study times was January2017 to December 2017 all the patients attendinghaemodialysis unit at Gazi Medical College. A total 236patients were selected. Among them 151 patients werevaccinated and 67 patients vaccinated during dialysis and 18patients were not vaccinated. There was a history of bloodtransfusion of 145 patients and 91 patients have no history ofblood transfusion. There were 30 patients were HbsAg positiveout of 236 patients. 12 patients were vaccinated before thediagnosis of CKD and 18 were not vaccinated. The finding ofthe study will help the doctor and policy maker totake appropriate measurement to decrease the morbidity andmortality from Hep B infection who are receivinghaemodialysis.

Awareness Regarding Neonatal Jaundice Treatment Among Mothers: A Descriptive Study in Tertiary Level Hospital

Background: Neonatal Jaundice (NNJ) is a major publichealth problem worldwide and is present among 50 – 60 % offull term and 80% of preterm newborns. This study wascarried out in order to assess the knowledge on neonataljaundice treatment among the mothers in a selected tertiarylevel hospital of Jessore district town.Methodology: It was a descriptive type of cross – sectionalstudy. 110 samples were selected by non – randomizedpurposive sampling technique with the administration of apretested modified and semi – structured questionnaire by faceto face interview.Results: Study found that majority of the respondents(54.55%) was in the age group 20 – 25 years. Regardingknowledge on preventive measures of NNJ 95.45%respondents had knowledge on ‘‘putting jaundiced baby underdirect sun light’’, 41.82% had knowledge on ‘phototherapy’.97.27% indicated’’ consult with doctor` A significant associationwas also found between age and `consultation with doctor`(p=0.025).Conclusion: Awareness should be created among theexpecting mothers about neonatal jaundice and encouragethem to take preventive measures to reduced neonatalmortality and morbidity.

Malaysian consensus statement for the diagnosis and management of acromegaly / Journal of the ASEAN Federation of Endocrine Societies

@#<p style="text-align: justify;">In Malaysia, acromegaly is under-recognised with only 10-15% of the expected number of cases from prevalence estimates, having been diagnosed and managed in established endocrine centres with access to multidisciplinary care. This is mainly due to lack of awareness and standardised approach in diagnosing this disease resulting in delay in diagnosis and management with suboptimal treatment outcomes. This first Malaysian consensus statement on the diagnosis and management of acromegaly addresses these issues and is based on current best practices and latest available evidence so as to reduce the disease burden on acromegaly patients managed in the Malaysian healthcare system.</p>

Comparative study between the corneal volume in mild and severe keratoconic eyes using pentacam tomography

Background: Keratoconus is the most common corneal ectasia. It usually appears in the second decade of the life and affects both genders and all ethnicities. Tomographic-based data have added significantly more information to the screening of corneal ectasia. In addition to anterior corneal analysis, tomography also provides information about the posterior cornea and the pachymetric distribution, which can increase our ability to identify early and subtle corneal changes

Aim of the Work: The main aim is to determine how the corneal volume measurement changes in different diameters of corneal tissue, in the central 3 mm and 5 mm in mild and severe cases of keratoconus; in an attempt to quantify the loss of corneal tissue in keratoconus

Patients and methods: This cross-sectional study included 20 eyes of keratoconic patients, from 15 to 36 years old. They were divided into 2 groups, each group included 10 eyes: Group A: mild keratoconic cases with steepest keratometry reading lower than 45 D. Group B: severe cases with steepest keratometry greater than 52 D, All cases were diagnosed as keratoconus using pentacam parameters

Results: Corneal volume at 3 and 5 mm diameter was significantly lower in the severe keratoconic cases than in mild cases [P<0.01]

Conclusion: based on the data in our study, we think the effect of keratoconus is not limited to corneal thickness. Rather, it affects all anterior segment parameters of the eye and results in significant alternations with the progression of the disease. There is a clear reduction of corneal volume in early keratoconus, and such reduction increases significantly with the severity of the disease. Measurement of corneal volume could prove to be a useful tool to monitor the progression of the disease and in other applications, such as assessing the effect of treatments including corneal collagen crosslinking and implatation of Intacs

Recommendations: Further studies on a larger scale of patients are needed to confirm the results obtained by this work

Frame by frame analysis of glottic closure in fasting subjects

Objective: The purpose of the study is to examine vocal fold closure in fasting subjects using frame by frame analysis

Subjects and Methods: Twenty-two male subjects were recruited for this study. All subjects were evaluated while fasting and non fasting. Frame by frame analysis of at least three glottic cycles was performed and reported as a mean closed quotient. The degree of phonatory effort and vocal fatigue was also reported

Results: The mean closed quotient for all subjects while non fasting was 0.427 +/- 0.098 and while fasting 0.441 +/- 0.073, with no significant difference between the two [p value 0.417]. There was a significant increase in the phonatory effort while fasting [0.23 non fasting vs. 0.77 fasting, p value 0.036]

Conclusion: There is no change in the mean closed quotient in male subjects while fasting. However, most subjects exhibit a significant increase in phonatory effort

Epidemiological and clinical features of salmonella typhi infection among adult patients in qatar: a hospital-based study

Objectives: We sought to describe the epidemiological and clinical features of typhoid fever in Qatar

Methods: We conducted a retrospective study of adult patients treated for typhoid fever at Hamad General Hospital and Alkhor Hospital between 2005 and 2012

Results: The mean age of the 354 patients enrolled in the study was 28.4+/-9.3 years; 296 [83.6%] were males. There were 42, 48, 39, 44, 46, 47, 52, and 36 cases of adults with typhoid fever in 2005, 2006, 2007, 2008, 2009, 2010, 2011, and 2012, respectively. Overall, 343 [96.9%] patients had a history of travel to endemic areas. Among them, 93.0% acquired typhoid fever in the Indian subcontinent. Fever was observed in all cases, and the other predominant symptoms were abdominal pain [38.1%], diarrhea [35.6%], and headache [33.1%]. Salmonella typhi, showed high resistance to ciprofloxacin [n = 163; 46.0%], and low resistance to ceftriaxone [n = 2; 0.6%]. Four patients developed intestinal perforation, which was surgically repaired in two cases. Two patients [0.6%] died

Conclusions: Typhoid fever was frequent among immigrants to endemic areas. Travelers returning from endemic areas with suspected typhoid fever should be treated empirically with third-generation cephalosporin after obtaining appropriate cultures. Moreover, preventive measurements such as education on food and water hygiene, and effective vaccination of travelers should be practiced widely among travelers to endemic areas to reduce morbidity and mortality

Safety of conscious sedation in patients undergoing endoscopic retrograde cholangio pancreatography

Objective: to assess the safety of conscious sedation in patients undergoing endoscopic retrograde cholangio pancreaticography [ERCP]

Study Design: an observational study

Place and Duration of Study: department of Gastroenterology, Liaquat National Hospital, Karachi, from April 2010 to April 2015

Methodology: all patients underwent ERCP procedure under midazolam and/or nalbuphine were included. Safety was assessed by monitoring the hemodynamics and complications during procedure till discharge from hospital. SPSS version 20 was used for descriptive analysis

Results: a total of 550 procedures were enrolled for the study. The mean age of the patients was 50.85 +/- 15.66 years. There were 197 [35.8%] males. Out of 550 procedures, only 2 [0.4%] reported complications. The study reports a success rate of 531 [96.5%] procedures who underwent ERCP with conscious sedation. Only 19 [3.5%] cases could not be completed successfully under conscious sedation and were converted to general aneasthesia

Conclusion: the present study shows that ERCP technique is safe under conscious sedation as it delivers balanced tranquillity

Post-operative anticipation of outcome after cholecystectomy

Background: A substantial group of patients with gallstone disease experience negative outcome after surgical removal of the gallbladder [cholecystectomy]. Early identification of these patients is important

Purpose: The purpose of the study was to recognize predictors [trait anxiety and clinical symptoms] of negative symptomatic outcomes at 5 weeks after cholecystectomy

Materials and Methods: Consecutive patients [n=66], 18-60 years, with symptomatic gallstone disease, completed symptom checklists and the state-trait anxiety inventory preoperatively and at 6 weeks after cholecystectomy. Results: High trait anxiety was the only predictor of persistence of biliary symptoms at 6 weeks after cholecystectomy [OR=6.79]

Conclusion: In addition to clinical symptoms, high trait anxiety is a predictor of negative symptomatic outcome at 6 weeks after cholecystectomy. Trait anxiety should be evaluated to aim at a patient-tailored approach in gallstone disease

Vocal Symptoms and Acoustic Findings in Menopausal Women in Comparison to Pre-menopause Women with Body Mass Index as a Confounding Variable

OBJECTIVES: To compare the prevalence of phonatory symptoms in menopausal women compared to pre-menopause women with body mass index (BMI) as a confounding variable. METHODS: A total of 69 women, 34 menopausal and 35 pre-menopausal were invited to participate in this study. Demographic variables included age, smoking, and BMI. All subjects were asked about the presence hoarseness, loss of high or low frequencies, pitch breaks, throat clearing, dryness in the throat and vocal fatigue. Acoustic analysis was performed and the Voice Handicap Index (VHI)-10 was filled by all the subjects. RESULTS: There was a significantly higher prevalence of throat clearing and dryness in the menopausal group compared to the pre-menopause group with a P value of 0.035 and 0.032 respectively. When BMI was taken into account, there was no statistically significant difference in the prevalence of any of the phonatory symptoms in menopausal women with high BMI and pre-menopause. There was no statistically significant difference in the means of any of the acoustic parameters between the menopausal group and pre-menopausal group. There was no significant difference in the mean VHI-10 between the menopause group and the pre-menopause (P = 0.652). CONCLUSIONS: The results of this investigation substantiate the importance of fat as an alternative source of estrogen which can mask some of the phonatory symptoms.

Impacts Of Three Different Relaxation Techniques On Mood States Among Athletes

Relaxation technique is a method, process, procedure or activity that helps a person to relax. There are several methods of relaxation techniques that can be used proven beneficial to improve the individual state of relaxation. Relaxation can be performed individually or in a group. With suitable technique of relaxation, it will improve quality of life as well as emotional and physical. This study aims to investigate the impact of three different relaxation techniques, namely Autogenic (AGR), Progressive Muscle (PMR) and Music Relaxation (MR) on mood states among Universiti Sultan Zainal Abidin (UniSZA) athletes. Eighty UniSZA athletes aged between 18 to 25 years old were randomly assigned into four groups which were AGR, PMR, MR and control group. Each groups consisted of 20 subjects which were male and female athletes with multidiscipline of the sports involvement. The mood states were determined by Brunel Mood Scale (BRUMS) during pre and post-intervention. The subjects in the three intervention groups received relaxation training twice a week for four weeks, 30 minutes per sessions. While, a control group not received any relaxation training during the intervention time. Repeated measure ANOVA conducted showed that the two parameters in BRUMS significantly changes in post-intervention such vigour (F=16.083, p<0.0001) and confusion (F=3.412, p=0.022). Other negative mood scores showed no significant changes such; (anger; F=2.235, p=0.091, depression; F=0.960, p=0.416, fatigue; F=0.724, p=0.540, tension; F=16.083, p=0.913).The results of Pairwise Comparison revealed that the three types of relaxation techniques (AGR, PMR and MR) effective to enhance vigour (positive mood) score among the adult subjects. In this study, PMR was the most effective relaxation technique followed by AGR and MR to regulate the mood state among adults.

Impacts Of Three Different Relaxation Techniques On Mood States Among Athletes

@#Relaxation technique is a method, process, procedure or activity that helps a person to relax. There are several methods of relaxation techniques that can be used proven beneficial to improve the individual state of relaxation. Relaxation can be performed individually or in a group. With suitable technique of relaxation, it will improve quality of life as well as emotional and physical. This study aims to investigate the impact of three different relaxation techniques, namely Autogenic (AGR), Progressive Muscle (PMR) and Music Relaxation (MR) on mood states among Universiti Sultan Zainal Abidin (UniSZA) athletes. Eighty UniSZA athletes aged between 18 to 25 years old were randomly assigned into four groups which were AGR, PMR, MR and control group. Each groups consisted of 20 subjects which were male and female athletes with multidiscipline of the sports involvement. The mood states were determined by Brunel Mood Scale (BRUMS) during pre and post-intervention. The subjects in the three intervention groups received relaxation training twice a week for four weeks, 30 minutes per sessions. While, a control group not received any relaxation training during the intervention time. Repeated measure ANOVA conducted showed that the two parameters in BRUMS significantly changes in post-intervention such vigour (F=16.083, p<0.0001) and confusion (F=3.412, p=0.022). Other negative mood scores showed no significant changes such; (anger; F=2.235, p=0.091, depression; F=0.960, p=0.416, fatigue; F=0.724, p=0.540, tension; F=16.083, p=0.913).The results of Pairwise Comparison revealed that the three types of relaxation techniques (AGR, PMR and MR) effective to enhance vigour (positive mood) score among the adult subjects. In this study, PMR was the most effective relaxation technique followed by AGR and MR to regulate the mood state among adults.

Risk factors of diabetic foot Charcot arthropathy: a case-control study at a Malaysian tertiary care centre

<p><b>INTRODUCTION</b>This study aimed to determine the risk factors of diabetic Charcot arthropathy of the foot among diabetic patients with and without foot problems.</p><p><b>METHODS</b>This was a case-control study involving diabetic patients attending the Diabetic Foot Care and Wound Management Clinic at University Malaya Medical Centre, Kuala Lumpur, Malaysia, from June 2010 to June 2011. Data on sociodemographic profiles, foot factors and diabetes characteristics was collected and analysed.</p><p><b>RESULTS</b>A total of 48 diabetic patients with Charcot arthropathy of the foot were identified. Data from these 48 patients was compared with those of 52 diabetic patients without foot problems. Up to 83.3% of patients with diabetic Charcot arthropathy presented with unilateral Charcot foot, most commonly located at the midfoot (45.8%). Patients with a history of foot problems, including foot ulcer, amputation, surgery or a combination of problems, had the highest (26-time) likelihood of developing Charcot arthropathy (odds ratio 26.4; 95% confidence interval 6.4-109.6). Other significant risk factors included age below 60 years, more than ten years' duration of diabetes mellitus and the presence of nephropathy.</p><p><b>CONCLUSION</b>A history of prior diabetic foot problems is the greatest risk factor for developing diabetic Charcot arthropathy, compared with other risk factors such as diabetes characteristics and sociodemographic profiles. Preventive management of diabetic foot problems in the primary care setting and multidisciplinary care are of paramount importance, especially among chronic diabetic patients.</p>

Prevalence of anxiety and depression among doctors; the unscreened and undiagnosed clientele in Lahore, Pakistan

Objectives: To analyze prevalence of anxiety and depression among doctors serving in a tertiary care hospital in Lahore, with a study of impact of relevant demographic features

Methods: A cross sectional study was conducted at Combined Military Hospital, Lahore, from February 2014 to Jan 2015. Participants were doctors serving in subject hospital for at least six months duration. Standardized Hospital Anxiety Depression Score [HADS] inventory was selected as inventory. Formal approval from hospital ethical committee and written informed consent from participants were obtained. Demographic characteristics of participants were recorded as independent variables; anxiety and depression scores being outcome variables. Data analysis was done via descriptive statistics [SPSS-20], qualitative data expressed as frequencies, percentages; quantitative as mean +/- standard deviation[SD]. Cross tabulation was done via chi-square, p-value < 0.05 considered as significant

Results: Out of 203 volunteers, 97[47.78%] responded. Score of anxiety was 7.04 +/- 4.470, maximum being 19, scores of depression was 4.94 +/- 3.605, maximum score being 15. Mild to moderate anxiety and depression were revealed in 33[34%] and 24[24.8%] respectively, while 7[7.2%] and 1[1.0%] had severe anxiety and depression respectively. There was strong positive relation between anxiety and depression[p<0.001]. There was significant impact of service years on depression[p-0.011] and gender on anxiety[p-0.002],9[17.31%] males and 24[53.33%] females had mild to moderate anxiety while 4[7.69%] males and 3[6.66%] females revealed severe anxiety and other variables did not reveal significant impact on HADS scores

Conclusion: Doctors showed high grades of anxiety and depression. They must be promptly screened and managed at all medical institutions

Allergic fungal rhinosinusitis: rhinosinusitis microbiologic and pathologic review

Objective: To observe the various aspects of allergic fungal rhinosinusitis [APRS]

Study Design: Prospective Study

Place and Duration of Study: This study was conducted at Department of Head and Neck Surgery, Civil Hospital Quetta and Chaudhary Rehmat Ali Memorial Trust Hospital, Lahore from 1[st] January 2015 to 30[th] June 2015

Materials and Methods: Sixty seven patients suffering from chronic rhinosinusitis with polyps were included in this study

They were assessed clinically, computed tomography and histopathologic and mycologic monitoring. Depending on the presence or absence of allergic mucin and mycelial elements in the sinus, the patients were studied for different parameters

Results: The mean age of 36.4 years with ranged from 14 to 51 and male to female ratio was 1.6:1. Out of these presumed 67 APRS patients, 8 had positive fungal cultures. Remaining 59 patients with EM either had negative fungal cultures and these patients were thought to have insufficient evidence for a pathologic diagnosis of APRS

Conclusion: For the diagnosis of APRS, the detection of fungal elements and allergic mucin should be considered

Serum concentration of zinc in healthy pregnant women versus pre-eclamptic pregnant women: a case control study in Lahore, Pakistan

Objective: To find out serum zinc level in healthy pregnant women and pre-eclemptic pregnant women

Study Design: Ramdomized controlled trial study

Place and Duration of Study: This study was conducted at Department of Pathology, Lady Willingdon Hospital, Lahore and at Lahore College for Women University, Lahore from March 2015 to September 2015

Materials and Methods: Size of sample was determined statistically by using table and119 [102 experimental group[51 pre-eclamptic pregnant women and 51 normal pregnant women] and 17 control group] blood samples were collected randomly

Results: The average zinc concentration in healthy pregnant group was found 1.44 +/- 0.14 mg/l as compared to pre- eclamptic pregnant group 0.25 +/- 0.02 mg/l. In pregnant women average zinc concentration was found to be decreasing with trimester. The average systolic blood pressure in healthy pregnant women was 113.83 +/- 1.74 mm/Hg as compared to the pre-eclamptic pregnant women was 145.34 +/- 1.68 mm/Hg. Average diastolic blood pressure in healthy pregnant women, was found 75.23 +/- 1.46 mm/Hg as compared to pre-eclamptic pregnant women, which was 92.76 +/- 1.80 mm/Hg

Conclusion: Zinc level in the blood serum of pre-eclamptic pregnant women was found lower as compared to healthy pregnant women. Low blood serum zinc level is associated with the elevated systolic and diastolic blood pressure also

Assessment of prevalence of the most common cancers at a tertiary care hospital in Al Ahsa, Kingdom of Saudi Arabia

Objective: To assess the prevalence of most common cancers

Study Design: Observational / analytic study

Place and Duration of Study: This study was conducted at King Fahd Hospital [KFH], Al Ahsa, Kingdom of Saudi Arabia [KSA] from January 2015 to December 2015

Materials and Methods: This study was conducted among 200 cancer patients, visited KFH, Al Ahsa. Total 200 patients were included in the study. Adult patients of age 15 to 85 years were included. The data was analyzed using SPSS 16

Results: Among total 200 cancer patients, males accounted for 108 [54%] and females for 92 [46%]. Age of the male patients at presentation was 45 to 85 [mean 65] years and age of the female patients was 49 to 83 [mean 66] years. Only 2 cases of Osteosarcoma were found in young age males [21 to 23 years], and only 2 cases of breast cancer were found in young age females [32 to 34 years]. Among males, the most frequent malignancies were colorectal carcinoma, lymphoma, leukemia, lung cancer, prostate cancer, urolithial cancer and other cancers [mesothelial, pancreas, stomach and osteosarcoma], respectively. Among females, the most frequent malignancies were breast cancer, thyroid cancer, colorectal carcinoma, lymphoma, leukemia, renal cell carcinoma and other cancers [gall bladder, pancreas, ovary and uterus], respectively

Conclusion: Among males, colorectal carcinoma, lymphoma, leukemia, lung cancer and prostate cancer were the most common cancers. Among females, breast cancer, thyroid cancer, colorectal carcinoma, lymphoma and leukemia were the most common cancers. Our results alarm to initiate the cancer control programs to decrease the cancer incidence in our region