RESUMEN
Omental cysts are rare and usually present with painless abdominal distension. Complete excision of the cyst is the treatment of choice. We report a three year old boy who presented with the complaints of vague abdominal pain and distension. He had an uneventful laparotomy with complete excision of the cyst
RESUMEN
Two promising antibiotics, JF-A and JF-B were isolated from the chloroform extract of a Banglaeshi Streptomyces strain. The mean zones of inhibition produced by the chloroform extract [400 ug/disc], JF-A [200 ug/disc] and JF-B [200 ug/disc] against 19 pathogenic bacteria were found to be 9-50, 12-38 and 10-41 mm while those produced by a standard antibiotic, kanamycin were 11-40 mm at 30 ug/disc. MICs of JF-A and JF-B were determined to be 64 ug/ml against Bacillus subtilis and 64 and 128 ug/ml against Shigella sonnei, respectively. The extract and the antibiotics were also tested for cytotoxicity against Artemia salina nauplii and LC50 values of 23.26, 18.05 and 32.27 ug/ml were obtained. 90% mortality of shrimp nauplii was observed at 69.18, 50.12 and 110.91 ug/ml, respectively. In a potato disc bioassay, the chloroform extract at 25 ug/disc demonstrated 37.39% inhibition of crown gall tumour induced by G -ve Agrobacterium tumefaciens B6 and the result was statistically significant [P < 0.05]. The sub-acute toxicity studies on the JF-A and JF-B reflected innocuous nature of these antibiotics on hepatic, renal and haemopoietic system of rats at 1 mg/kg b.w. on daily administration for 21 consecutive days. This is also confirmed by detailed histopathological studies. No mortality was observed in experimental animals