RESUMEN
Our aim was to investigate the possible relationship between myeloperoxidase [MPO] and myocardial damage markers such as heart-type fatty acid-binding protein [H-FABP] and troponin T [TnT] in patients with chronic heart failure [HF]. Materials and Forty-two consecutive patients [age range: 27-80 years] with chronic HF were enrolled in the study. Serum H-FABP, TnT and MPO levels were measured. Routine biochemical and clinical parameters were recorded. Echocardiographic examinations were performed on all patients. A linear regression analysis was performed to determine the correlates of serum H-FABP. The MPO, H-FABP and TnT levels were 255 +/- 227, 60.6 +/- 48.5 and 0.07 +/- 0.15 ng/ml, respectively. In multiple linear regression analysis, age [beta = -0.36, p = 0.006], creatinine level [beta = 0.3, p = 0.024] and serum MPO level [beta = 0.41, p = 0.009] were significant determinants of H-FABP levels. Bivariate predictors were not significantly associated with TnT levels in linear regression analyses. The MPO was significantly associated with serum H-FABP levels but not with TnT