Toxicity of chloroform administered to rats at a sublethal dose

This study was undertaken to determine some physiological, haematological and biochemical toxic effects of chlorofom in an animal model. Chloroform administered at a sublethal dose resulted in recognizable disturbances in serum alanine aminotransferase and lactic dehydrogenase activities, blood glucose and cholesterol levels, haemoglobin concentration, haematocrit value, erythrocyte count as well as Ca[2]+ and Fe[2]+ concentrations in whole blood and liver

Influence of zinc pretreatment on lymphocyte transformation during cadmium exposure in rats

The present study shows that in vivo exposure of rats to a lethal dose of cadmium [96 hours LD 50] significantly diminished lymphocyte blastogenic transformation by PHA, in the whole blood and spleen. pre-treatment with zinc [131.25 mg Zn+**2 /kg] protected rats from the inhibitory effect of Cd administered 24 hours later, as lymphocyte blastogenic transformation values recorded were changed when compared with controls