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1.
J Cancer Res Ther ; 2020 Jul; 16(3): 661-664
Artículo | IMSEAR | ID: sea-213678

RESUMEN

The present case report is a case of peripheral dentinogenic ghost cell tumor (PDGCT), an extremely rare solid benign neoplastic variant of calcifying cystic odontogenic tumor of the gingiva mimicking clinically as pyogenic granuloma, fibroma, peripheral ossifying fibroma, and peripheral giant-cell granuloma. A 24-year-old male reported with painless, firm, solitary, sessile, smooth-surfaced, nonulcerative, nonpulsatile, well-defined swelling measuring ≈12 mm × 9 mm in the interdental gingiva of the teeth #13 and #14 extending to the mucogingival junction. Intraoral periapical radiographic showed a normal trabecular pattern with mild radiolucency without bony expansion, periapical lesion, and resorption of the adjacent teeth. The diagnosis was established by histopathologic examination. Very few cases of this entity have been documented in the literature. The present case report aims to document this rare entity and emphasizes on the fact that histopathological examination of every localized gingival growth should be included in the treatment planning to differentiate with other commonly found lesions

2.
J Cancer Res Ther ; 2019 May; 15(3): 615-619
Artículo | IMSEAR | ID: sea-213393

RESUMEN

Background: Micronucleus (MN) has been proved to be an important biomarker of genomic damage. Leishman Giemsa (LG) cocktail, being a relatively new staining technique, has not been used in exfoliative cytology. The aim of this study is to observe and compare the micronuclei (MN) frequency in potentially malignant disorders (PMDs) and also to compare the staining efficacy of May-Grünwald Giemsa (MGG), LG cocktail, and Papanicolaou (PAP) for micronuclei in exfoliated oral mucosal cells. Materials and Methods: Three smears were prepared from each 30 controls (buccal mucosa) and 120 patients (40 oral submucous fibrosis, 40 lichen planus, and 40 leukoplakia) clinically diagnosed with having one of the PMDs of the oral cavity stained with PAP, MGG, and LG cocktail stains. MN frequency (No. of MN/1000 cells) was evaluated and compared between the cases and the controls. Comparison between the three different stained smears was also made to determine the clarity and efficacy of the stains. Results: LG cocktail gave comparatively better results followed by PAP and MGG. Statistically significant results (P < 0.05) were obtained, using Mann–Whitney test for comparison of MN frequency between cases and controls. Conclusion: LG cocktail is an easy, cost- effective, and one step technique comparable to PAP staining; however, it warrants further study in its potential application in screening of oral cancer.

3.
J Ayurveda Integr Med ; 2015 Jan-Mar; 6(1): 45-49
Artículo en Inglés | IMSEAR | ID: sea-173652

RESUMEN

The aim of the present study was to investigate the clinical efficacy of herbal medicines (1 gm tulsi and 1 gm turmeric mixed in glycerine base) for the treatment of oral submucous fibrosis (OSMF). Forty‑one patients in the age group of 17- 56 years without any systemic complications were included in the study. The patients were treated with medicines, which were to be applied 3-4 times a day. Blood samples were collected before and after treatment to screen for any systemic changes due to these medications. Burning sensation and mouth opening were recorded before and after treatment. Patients were followed up on monthly subsequent visits for three months. Changes in the burning sensation on visual analogue scale (VAS) scale and difference in the mouth opening were analyzed statistically. A statistically significant improvement was seen in both burning sensation and mouth opening. Tulsi and turmeric offers a safe and efficacious combination of natural products available for symptomatic treatment of OSMF.

4.
Artículo en Inglés | IMSEAR | ID: sea-153042

RESUMEN

Background: Refractive error is the most common cause of blindness which can be corrected easily using simple modality like spectacles but because of ignorance, stigmas and cost related issues it is underutilized. Aims & Objective: Study to assess the psychosocial aspects of refractive error and effectiveness of health education in correcting stigmas related to spectacle use in high-school students of rural India. Material and Methods: This was a cross sectional study in which total of 255 high school students from a school near Bhopal were included. The responses were recorded on a pre-designed and pre-tested questionnaire. The health education was provided to all the participants and they were reassessed after one month using same questionnaire. The researcher used the STATA version 12.1 for data entry and analysis. Results: Amongst total of 255 students, 165 were males and 90 were females. During initial phase most of the respondents believed that common reasons for low vision were nutritional deficiency (68%) and bad eye care (56%). The respondents refused to use spectacles at all if needed as spectacles are cosmetically unacceptable (62%) , fear of rejection from opposite sex (54%) and likely teasing from colleagues (36%).Following health education there were statistically significant changes in the knowledge, attitude and care seeking behaviour of spectacle use. Only two parameters i.e. cosmetic acceptance of spectacles and that traditional methods were more than spectacles did not changed significantly. Conclusion: Prevalent stigmas regarding spectacle use among students of rural India were effectively corrected with health education.

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