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Background: Preeclampsia is a multisystem disorder of pregnancy, which complicates 3%-5% of pregnancies in the western world. It is a major cause of maternal morbidity and mortality worldwide. The cardinal clinical features of the condition are hypertension and proteinuria occurring after 20 weeks gestation in women who were not previously known to be hypertensive
Objective: This study was aimed to assess the efficacy of C3 estimation and measurement of bilateral uterine artery Doppler before 20 weeks of pregnancy for prediction of preeclampsia in primigravida
Methods: The study was performed at the Antenatal Care Unit, Obstetrics and Gynecology Department, Sayed Galal Hospital, Al Azhar University on 131 pregnant women at 14-20 gestational weeks during period from July 2017 to December 2017 gestation attending
Results: On follow up the population of the study 131 pregnant women had completed the study that were classified to 119 [90.8%] with no pre-eclampsia and 12 [9.2%] developed preeclampsia, As regards the Patients characteristics there was no statistical significant difference between the two groups as regard age, height, weight, gestational age, SBP and DPB at enrollment [p-value>0.05]. There was a significant difference regarding BMI as [p value < 0.05], with more increasing BMI and decreasing gestational age at delivery in preeclampsia group in comparison with the no preeclampsia group. As regards the C3, there was statistically highly significant difference between the two groups regarding serum C3 level as p value <0.05, with lower levels of C3 serum levels in preeclampsia group. Receiver operator characteristics [ROC] curves were constructed for estimating the association between pre-eclampsia and serum C3 level. A significant association was found with serum C3 level being a significant predictor with lower values in cases with pre-eclampsia than in normal cases [area under the curve [AUC] = 0.935, 95% CI [0.878 to 0.9711.35], best cut off [
Conclusion: This study demonstrates that lower level of maternal serum C3 in the early second trimester [14-20 weeks gestation] and abnormal increasing in uterine artery indices [PI and RI] are associated with developing pre-eclampsia several months later in pregnancy
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OBJECTIVE@#To investigate the protective effects of aqueous seed extracts of fennel "Foeniculum vulgare" (FVE) and caraway "Carum carvi" (CCE) on liver, kidney and reproductive organs in female rats against cadmium chloride (CC) intoxication.@*METHODS@#A total of 36 adult female rats were divided into six groups, six in each group. Control group (fed normal diet), CC-treated group (50 mg CC/kg diet), CCE-treated group (150 mg CCE/kg diet), CCE + CC group, FVE (150 mg/kg diet) and FVE + CC. One month later, all rats were sacrificed and all samples were collected at proestrus phase.@*RESULTS@#The toxic effects of CC were confirmed biochemically by significant increase of serum concentration of liver enzymes (P < 0.05), and creatinine (P < 0.001). Moreover, CC increased significantly the serum level of malondialdehyde (MDA) and decreased the total antioxidant capacity (TAC) (P < 0.001). In addition, serum concentrations of estrogen, progesterone, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) were significantly decreased (P < 0.01). Histopathologically, CC-treated group revealed marked pathological changes in renal, hepatic, ovarian and uterine tissues. All toxic findings observed in liver and kidney with CC treatment were found to be ameliorated markedly after co-treatments with FVE or CCE. Furthermore, co-treatment of FVE with CC improved significantly all studied reproductive parameters (P < 0.01).@*CONCLUSIONS@#Both FVE and CCE could be used as efficient treatments for liver and kidney against CC intoxication. Moreover, FVE could be utilized as a potent treatment to protect and improve female fertility from cadmium intoxication.
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Objective To investigate the protective effects of aqueous seed extracts of fennel “Foeniculum vulgare” (FVE) and caraway “Carum carvi” (CCE) on liver, kidney and reproductive organs in female rats against cadmium chloride (CC) intoxication. Methods A total of 36 adult female rats were divided into six groups, six in each group. Control group (fed normal diet), CC-treated group (50 mg CC/kg diet), CCE-treated group (150 mg CCE/kg diet), CCE + CC group, FVE (150 mg/kg diet) and FVE + CC. One month later, all rats were sacrificed and all samples were collected at proestrus phase. Results The toxic effects of CC were confirmed biochemically by significant increase of serum concentration of liver enzymes (P < 0.05), and creatinine (P < 0.001). Moreover, CC increased significantly the serum level of malondialdehyde (MDA) and decreased the total antioxidant capacity (TAC) (P < 0.001). In addition, serum concentrations of estrogen, progesterone, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) were significantly decreased (P < 0.01). Histopathologically, CC-treated group revealed marked pathological changes in renal, hepatic, ovarian and uterine tissues. All toxic findings observed in liver and kidney with CC treatment were found to be ameliorated markedly after co-treatments with FVE or CCE. Furthermore, co-treatment of FVE with CC improved significantly all studied reproductive parameters (P < 0.01). Conclusions Both FVE and CCE could be used as efficient treatments for liver and kidney against CC intoxication. Moreover, FVE could be utilized as a potent treatment to protect and improve female fertility from cadmium intoxication.
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Aims: To locate the plane of mesh insertion whether it is onlay, inlay, sublay, or underlay. Design: Prospective study Place and Duration: Done at Bani suef hospital between May 2011 till May 2012 with follow till May 2014. Methodology: Twenty two patients, six were males sixteen were females with recurrent incisional hernias were included in the study with a mean age ± SD of 44 years ± 11.87, there were 14 patients presented after the first recurrence (Groups 1, 2), 7 patients after the second recurrence (Groups 3, 4) and only one for the third recurrence. There were no significant difference between patients presented by 1st and 2nd recurrence concerning the age, sex and level of hernia. To all patients a polypropylene mesh was applied, 12 onlay, 2 inlay, 5 sublay and 3 underlay. Results: There were two serosal lesions and only one perforation. There were 4(18%) patients with seroma, 1 (4.5%) with haematoma, 4 (18%) with infection, 3 (13.6%) with DVT, 1 (4.5%) with non fatal PE, and 1 (4.5%) respiratory failure. The highest incidence of complications were in the onlay repair, the lowest in the underlay repair. The patients were followed for two year, there were 6 recurrence (27.2%), most of them were in the onlay repair with the highest incidence in the inlay repair. The incidence of recurrence in the onlay to inlay was statistically non significant (P<0.5), the onlay to the sublay was significant (P<0.05) and the onlay to the underlay was highly significant (P<0.02). Conclusion: It is to be concluded that when a patient with recurrent incisional hernia is in need for repair, it is better to avoid inlay technique, not to do the underlay and the onlay techniques, and recommended to do the sublay approach.
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Objective: To assess the sequelae of unilateral chewing on muscles of mastication via comparing the approximatemuscular volume (AMV) of the masseter (MM), medial pterygoid (MPM), temporalis (TM),superior and inferior lateral pterygoid muscles (SLPM/ILPM) bilaterally using MRI. Materials and methods:Twenty patients (16 females and 4 males) were selected from outpatient dental clinics of Kaser AlAini Hospitals, Cairo University, complaining from being unilaterally edentulous for one year or more. Alsosix fully dentate individuals (2 males and 4 females) were selected as control group. Magnetic ResonanceImaging (MRI) of the masticatory muscles was performed followed by measuring the approximate musclevolume (AMV) for each muscle bilaterally using the planimetry method. Results: Showed increase in theapproximate muscular volume (AMV) of the dentate side in both right side and left side edentulous patients.Conclusion: Our study shows the effect of long term unilateral chewing on decreasing the AMV in the nonfunctioningside, suggesting that measuring the approximate masticatory muscle volume using MRI couldbe helpful in detection of long-term functional disability of each muscle in comparison to adjacent muscles.
Objetivo: Avaliar as sequelas da mastigação unilateral sobre os músculos da mastigação por meio da comparaçãodo volume aproximado muscular (AMV) do músculo masseter (MM), pterigóideo medial (MPM), temporal(TM), músculos pterigóideos laterais superior e inferior (SLPM/ILPM) bilateralmente usando ressonânciamagnética. Materiais e métodos: Vinte pacientes (16 mulheres e 4 homens) foram selecionados a partir deambulatórios odontológicos do Hospital Kaser Al Aini, Universidade do Cairo; todos os participantes eram unilateralmentedesdentados há um ano ou mais. Também, seis indivíduos totalmente dentados (2 homens e 4mulheres) foram selecionados como grupo controle. Imagem por Ressonância Magnética (RM) dos músculosmastigatórios foi realizada seguido pela medição do volume muscular aproximada (AMV) para cada músculobilateral utilizando o método de planimetria. Resultados: Foi observado aumento no volume aproximadomuscular (AMV) do lado dentado em ambos os lados direito e esquerdo de desdentados laterais. Conclusão:Este estudo mostra o efeito em longo prazo da mastigação unilateral na diminuição da AMV no lado nãofuncional, o que sugere que a medição do volume muscular mastigatório aproximado usando ressonânciamagnética pode ser útil na detecção de deficiência funcional de cada músculo em comparação com músculosadjacentes em longo prazo.
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Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Anodoncia/fisiopatología , Masticación/fisiología , Músculos Masticadores/fisiopatología , Análisis de Varianza , Espectroscopía de Resonancia MagnéticaRESUMEN
Renal stones are a life long disease characterized by formation of solid concretions within the kidney or its drainage system. The extra corporeal shock wave lithotripsy is widely used in the treatment of calyceal stones, for any given location within the calyceal system.stone, free rate varies with increasing stone size, stone composition and site of the stotne. This study was conducted to evaluate the eftectivenoss, stone free rate and complications of ESWLin the treatment of calyceal stones, also to evaluate the eftect of urinary tract infection on success rate.This study included 25 patients schoduled for ESWL for calyceal calculi exclusion crileria were body weight more than 120 Kg and stone diameter more than 2.5 cm. ESWL was done with the lithostar lithotripter. [SIEMENS LITHOSTAR II] Post ESWL assessment by plain x-ray [KUB] one day and 2 weeks after. Follow up was done by KUB monthly until patient is stone free or ESWL terminated it was found that in patients with upper calyceal stones, the success rate was 83.3%, in lower calyceal stones and in combined stones, it was 57.1%. Middle calyceal stones were all in combind cases lower calyceal stones have high success rate for the obtuse infundibulopelvic angle, wide calyceal neck and short calyx. According to number of stones, the success rate for multiple stones was 60%, while, in single stones, it was 86.6%. According to the stone burden the success rate for stones less than 1 cm was 84.6% but for stones more than 1 cm, it was 66.6%. According to the number of sessions, the mean number of sessions was 2.6 which is higher than other studies as the mean of loading voltage was 16.4 bkilovolt which is relatively low. According to stone composition, the best results were for uric acid dihydrate and calcium phosphate, the next result was for calcium oxalate dihydrate, the worst was for calcium oxalate monohydrate. According to urine culture and urosepsis, it was found that 8% of sterile cases become Infected post ESWL. Inspite of its few complications, ESWL, when properly done and when correctly indicated still provides a marvelous alternative way to solve the problem of urinary stones